Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ubiquitin-like protein ligase activity	AMFR FBXO40 RNF7 RNF31 MYCBP2 ZNF451 RNFT1 RNF8 RNF122 RNF139 TRIP12 UBR7 FBXO30 SIAH3	2.10e-09	398	88	14	GO:0061659
GeneOntologyMolecularFunction	ubiquitin protein ligase activity	AMFR FBXO40 RNF7 RNF31 MYCBP2 RNFT1 RNF8 RNF122 RNF139 TRIP12 UBR7 FBXO30 SIAH3	8.99e-09	372	88	13	GO:0061630
GeneOntologyMolecularFunction	ubiquitin-like protein transferase activity	AMFR FBXO40 RNF7 RNF31 MYCBP2 ZNF451 RNFT1 RNF8 RNF122 RNF139 TRIP12 UBR7 FBXO30 SIAH3	5.03e-08	512	88	14	GO:0019787
GeneOntologyMolecularFunction	aminoacyltransferase activity	AMFR FBXO40 RNF7 RNF31 MYCBP2 ZNF451 RNFT1 RNF8 RNF122 RNF139 TRIP12 UBR7 FBXO30 SIAH3	8.08e-08	532	88	14	GO:0016755
GeneOntologyMolecularFunction	ubiquitin-protein transferase activity	AMFR FBXO40 RNF7 RNF31 MYCBP2 RNFT1 RNF8 RNF122 RNF139 TRIP12 UBR7 FBXO30 SIAH3	1.50e-07	473	88	13	GO:0004842
GeneOntologyMolecularFunction	acyltransferase activity	AMFR FBXO40 RNF7 RNF31 MYCBP2 ZNF451 RNFT1 RNF8 RNF122 RNF139 TRIP12 UBR7 FBXO30 SIAH3	7.01e-06	775	88	14	GO:0016746
GeneOntologyMolecularFunction	insulin-like growth factor I binding	IGF1R LRP2 ITGB3	2.29e-05	13	88	3	GO:0031994
GeneOntologyMolecularFunction	low-density lipoprotein particle receptor activity	LRP1 LRP2 SORL1	4.44e-05	16	88	3	GO:0005041
GeneOntologyMolecularFunction	insulin-like growth factor binding	IGF1R LRP2 ITGB3	7.62e-05	19	88	3	GO:0005520
GeneOntologyMolecularFunction	lipoprotein particle receptor activity	LRP1 LRP2 SORL1	1.04e-04	21	88	3	GO:0030228
GeneOntologyMolecularFunction	growth factor binding	IGF1R NTRK3 LRP2 TWSG1 ITGB3	6.35e-04	156	88	5	GO:0019838
GeneOntologyMolecularFunction	vascular endothelial growth factor receptor 2 binding	VEGFD ITGB3	8.44e-04	10	88	2	GO:0043184
GeneOntologyMolecularFunction	ubiquitin binding	AMFR RNF31 RNFT1 RNF8	1.29e-03	107	88	4	GO:0043130
GeneOntologyMolecularFunction	zinc ion binding	FBXO40 RNF7 RNF31 MYCBP2 PRIM1 RNF8 ADAMTS5 RNF139 TRIP12 UBR7 FBXO30	1.82e-03	891	88	11	GO:0008270
GeneOntologyMolecularFunction	transition metal ion binding	ADCY10 FBXO40 RNF7 RNF31 MYCBP2 PRIM1 RNF8 ADAMTS5 RNF139 MUC2 TRIP12 UBR7 FBXO30	2.06e-03	1189	88	13	GO:0046914
GeneOntologyMolecularFunction	ubiquitin-like protein binding	AMFR RNF31 RNFT1 RNF8	2.48e-03	128	88	4	GO:0032182
GeneOntologyMolecularFunction	vascular endothelial growth factor receptor binding	VEGFD ITGB3	2.50e-03	17	88	2	GO:0005172
GeneOntologyMolecularFunction	platelet-derived growth factor receptor binding	VEGFD ITGB3	2.50e-03	17	88	2	GO:0005161
GeneOntologyMolecularFunction	transmembrane receptor protein tyrosine kinase activity	IGF1R NTRK3 RYK	2.97e-03	65	88	3	GO:0004714
GeneOntologyMolecularFunction	intracellularly calcium-gated channel activity	ANO6 ANO5	3.46e-03	20	88	2	GO:0141147
GeneOntologyMolecularFunction	intracellularly calcium-gated chloride channel activity	ANO6 ANO5	3.46e-03	20	88	2	GO:0005229
GeneOntologyMolecularFunction	coreceptor activity	LRP1 ITGB3 RYK	3.96e-03	72	88	3	GO:0015026
GeneOntologyMolecularFunction	3',5'-cyclic-AMP phosphodiesterase activity	PDE7A PDE7B	4.19e-03	22	88	2	GO:0004115
GeneOntologyMolecularFunction	phospholipid scramblase activity	ANO6 ANO5	4.57e-03	23	88	2	GO:0017128
GeneOntologyBiologicalProcess	enzyme-linked receptor protein signaling pathway	DOK6 SFRP1 IGF1R MEGF8 ZNF451 NTRK3 CNMD LRP1 LRP2 PLAUR TWSG1 DMRT1 VEGFD ITGB3 RYK GAB1 SORL1	1.08e-05	1186	89	17	GO:0007167
GeneOntologyBiologicalProcess	chemotaxis	MEGF8 MYCBP2 ANO6 NTRK3 LRP1 LRP2 PLAUR VEGFD ITGB3 RYK GAB1	1.38e-05	517	89	11	GO:0006935
GeneOntologyBiologicalProcess	taxis	MEGF8 MYCBP2 ANO6 NTRK3 LRP1 LRP2 PLAUR VEGFD ITGB3 RYK GAB1	1.43e-05	519	89	11	GO:0042330
GeneOntologyBiologicalProcess	positive regulation of axon extension involved in regeneration	NTRK3 LRP1	1.84e-05	2	89	2	GO:0048691
GeneOntologyBiologicalProcess	positive regulation of axon regeneration	IGF1R NTRK3 LRP1	5.05e-05	17	89	3	GO:0048680
GeneOntologyBiologicalProcess	positive regulation of sprouting of injured axon	NTRK3 LRP1	5.51e-05	3	89	2	GO:0048687
GeneOntologyBiologicalProcess	positive regulation of neuron projection regeneration	IGF1R NTRK3 LRP1	6.05e-05	18	89	3	GO:0070572
GeneOntologyBiologicalProcess	cellular response to growth factor stimulus	SFRP1 IGF1R MEGF8 ZNF451 NTRK3 CNMD LRP1 LRP2 TWSG1 VEGFD ITGB3 GAB1 SORL1	7.00e-05	850	89	13	GO:0071363
GeneOntologyBiologicalProcess	regulation of cellular response to growth factor stimulus	SFRP1 ZNF451 CNMD LRP1 LRP2 TWSG1 VEGFD ITGB3 SORL1	7.20e-05	412	89	9	GO:0090287
GeneOntologyBiologicalProcess	regulation of axon extension	ADCY10 MEGF8 NTRK3 LRP1 RYK	8.78e-05	104	89	5	GO:0030516
GeneOntologyBiologicalProcess	positive regulation of axon extension	ADCY10 MEGF8 NTRK3 LRP1	9.34e-05	55	89	4	GO:0045773
GeneOntologyBiologicalProcess	protein modification by small protein conjugation or removal	AMFR RNF7 RNF31 MEGF8 MYCBP2 ZNF451 RNFT1 RNF8 RNF122 RNF139 TRIP12 ZRANB1 UBR7 FBXO30	1.02e-04	1009	89	14	GO:0070647
GeneOntologyBiologicalProcess	response to growth factor	SFRP1 IGF1R MEGF8 ZNF451 NTRK3 CNMD LRP1 LRP2 TWSG1 VEGFD ITGB3 GAB1 SORL1	1.03e-04	883	89	13	GO:0070848
GeneOntologyBiologicalProcess	regulation of axon extension involved in regeneration	NTRK3 LRP1	1.10e-04	4	89	2	GO:0048690
GeneOntologyBiologicalProcess	protein modification by small protein conjugation	AMFR RNF7 RNF31 MEGF8 MYCBP2 ZNF451 RNFT1 RNF8 RNF122 RNF139 TRIP12 UBR7 FBXO30	1.15e-04	893	89	13	GO:0032446
GeneOntologyBiologicalProcess	transcytosis	IGF1R LRP1 LRP2	1.47e-04	24	89	3	GO:0045056
GeneOntologyBiologicalProcess	cAMP metabolic process	ADCY10 PDE7A PDE7B	1.67e-04	25	89	3	GO:0046058
GeneOntologyBiologicalProcess	positive regulation of lysosomal protein catabolic process	LRP1 LRP2	1.83e-04	5	89	2	GO:1905167
GeneOntologyBiologicalProcess	chemoattraction of axon	LRP1 LRP2	1.83e-04	5	89	2	GO:0061642
GeneOntologyBiologicalProcess	axon extension involved in regeneration	NTRK3 LRP1	1.83e-04	5	89	2	GO:0048677
GeneOntologyBiologicalProcess	regulation of sprouting of injured axon	NTRK3 LRP1	1.83e-04	5	89	2	GO:0048686
GeneOntologyBiologicalProcess	protein ubiquitination	AMFR RNF7 RNF31 MEGF8 MYCBP2 RNFT1 RNF8 RNF122 RNF139 TRIP12 UBR7 FBXO30	1.85e-04	811	89	12	GO:0016567
GeneOntologyBiologicalProcess	regulation of extent of cell growth	ADCY10 MEGF8 NTRK3 LRP1 RYK	1.86e-04	122	89	5	GO:0061387
GeneOntologyBiologicalProcess	post-translational protein modification	AMFR RNF7 RNF31 MEGF8 MYCBP2 ZNF451 RNFT1 RNF8 RNF122 RNF139 TRIP12 ZRANB1 UBR7 FBXO30	1.95e-04	1074	89	14	GO:0043687
GeneOntologyBiologicalProcess	sprouting of injured axon	NTRK3 LRP1	2.73e-04	6	89	2	GO:0048682
GeneOntologyBiologicalProcess	axon extension	ADCY10 MEGF8 NTRK3 LRP1 RYK	2.98e-04	135	89	5	GO:0048675
GeneOntologyBiologicalProcess	positive chemotaxis	NTRK3 LRP1 LRP2 VEGFD	3.12e-04	75	89	4	GO:0050918
GeneOntologyBiologicalProcess	protein autoubiquitination	AMFR RNFT1 RNF8 RNF122	3.62e-04	78	89	4	GO:0051865
GeneOntologyBiologicalProcess	negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	SFRP1 ZNF451 LRP1 LRP2 TWSG1 SORL1	3.64e-04	218	89	6	GO:0090101
GeneOntologyBiologicalProcess	cell surface receptor protein tyrosine kinase signaling pathway	DOK6 IGF1R NTRK3 CNMD LRP1 PLAUR VEGFD ITGB3 RYK GAB1 SORL1	3.65e-04	747	89	11	GO:0007169
GeneOntologyBiologicalProcess	positive regulation of protein catabolic process in the vacuole	LRP1 LRP2	3.81e-04	7	89	2	GO:1904352
GeneOntologyBiologicalProcess	negative regulation of BMP signaling pathway	SFRP1 LRP2 TWSG1 SORL1	3.99e-04	80	89	4	GO:0030514
GeneOntologyBiologicalProcess	regulation of osteoblast proliferation	SFRP1 IGF1R ITGB3	4.22e-04	34	89	3	GO:0033688
GeneOntologyBiologicalProcess	regulation of cell size	ADCY10 MEGF8 ANO6 NTRK3 LRP1 RYK	4.31e-04	225	89	6	GO:0008361
GeneOntologyBiologicalProcess	negative regulation of cellular response to growth factor stimulus	SFRP1 CNMD LRP2 TWSG1 SORL1	4.83e-04	150	89	5	GO:0090288
GeneOntologyBiologicalProcess	regulation of chemotaxis	MEGF8 MYCBP2 ANO6 NTRK3 VEGFD RYK	6.32e-04	242	89	6	GO:0050920
GeneOntologyBiologicalProcess	cAMP catabolic process	PDE7A PDE7B	6.50e-04	9	89	2	GO:0006198
GeneOntologyBiologicalProcess	transforming growth factor beta receptor superfamily signaling pathway	SFRP1 MEGF8 ZNF451 LRP1 LRP2 TWSG1 DMRT1 SORL1	6.77e-04	445	89	8	GO:0141091
GeneOntologyBiologicalProcess	regulation of axon regeneration	IGF1R NTRK3 LRP1	6.84e-04	40	89	3	GO:0048679
GeneOntologyBiologicalProcess	amyloid-beta clearance	IGF1R LRP1 LRP2	6.84e-04	40	89	3	GO:0097242
GeneOntologyBiologicalProcess	positive regulation of response to wounding	IGF1R ANO6 NTRK3 LRP1	7.06e-04	93	89	4	GO:1903036
GeneOntologyBiologicalProcess	osteoblast proliferation	SFRP1 IGF1R ITGB3	7.35e-04	41	89	3	GO:0033687
GeneOntologyBiologicalProcess	axonogenesis	ADCY10 IGF1R MEGF8 MYCBP2 NTRK3 LRP1 LRP2 LAMB3 RYK	7.49e-04	566	89	9	GO:0007409
GeneOntologyBiologicalProcess	regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	SFRP1 ZNF451 LRP1 LRP2 TWSG1 DMRT1 SORL1	7.59e-04	347	89	7	GO:0090092
GeneOntologyBiologicalProcess	cyclic purine nucleotide metabolic process	ADCY10 PDE7A PDE7B	9.05e-04	44	89	3	GO:0052652
GeneOntologyBiologicalProcess	regulation of vascular endothelial growth factor receptor signaling pathway	CNMD VEGFD ITGB3	9.05e-04	44	89	3	GO:0030947
GeneOntologyBiologicalProcess	protein catabolic process	AMFR RNF7 MYCBP2 RNFT1 RNF8 LRP1 LRP2 RNF122 RNF139 TRIP12 ZRANB1 SORL1 SIAH3	9.62e-04	1115	89	13	GO:0030163
GeneOntologyBiologicalProcess	cyclic nucleotide metabolic process	ADCY10 PDE7A PDE7B	9.67e-04	45	89	3	GO:0009187
GeneOntologyCellularComponent	mucus layer	MUC2 MUC5AC	5.24e-05	3	88	2	GO:0070701
GeneOntologyCellularComponent	alphav-beta3 integrin-IGF-1-IGF1R complex	IGF1R ITGB3	1.05e-04	4	88	2	GO:0035867
GeneOntologyCellularComponent	Derlin-1 retrotranslocation complex	AMFR RNF139	4.83e-04	8	88	2	GO:0036513
MousePheno	petechiae	MEGF8 ITGB3 GAB1	1.93e-05	11	70	3	MP:0008816
Domain	EGF-like_CS	MEGF8 PAMR1 LRP1 LRP2 LAMA4 LAMB3 ADAM11 ITGB3 SORL1	3.19e-06	261	86	9	IPR013032
Domain	zf-TRAF_2	FBXO40 FBXO30	2.10e-05	2	86	2	PF15965
Domain	F-box_4	FBXO40 FBXO30	2.10e-05	2	86	2	PF15966
Domain	Fbxo30/Fbxo40	FBXO40 FBXO30	2.10e-05	2	86	2	IPR031890
Domain	EGF_1	MEGF8 PAMR1 LRP1 LRP2 LAMA4 LAMB3 ADAM11 ITGB3	2.29e-05	255	86	8	PS00022
Domain	EGF_2	MEGF8 PAMR1 LRP1 LRP2 LAMB3 ADAM11 ITGB3 SORL1	3.02e-05	265	86	8	PS01186
Domain	TIL_dom	LRP2 MUC2 MUC5AC	3.31e-05	14	86	3	IPR002919
Domain	Ldl_recept_b	LRP1 LRP2 SORL1	3.31e-05	14	86	3	PF00058
Domain	LDLRB	LRP1 LRP2 SORL1	3.31e-05	14	86	3	PS51120
Domain	LDLR_class-A_CS	LRP1 LRP2 CORIN SORL1	3.37e-05	40	86	4	IPR023415
Domain	LY	LRP1 LRP2 SORL1	4.12e-05	15	86	3	SM00135
Domain	LDLR_classB_rpt	LRP1 LRP2 SORL1	4.12e-05	15	86	3	IPR000033
Domain	Ldl_recept_a	LRP1 LRP2 CORIN SORL1	5.41e-05	45	86	4	PF00057
Domain	-	LRP1 LRP2 CORIN SORL1	5.90e-05	46	86	4	4.10.400.10
Domain	ZF_RING_2	AMFR RNF7 RNF31 MYCBP2 RNFT1 RNF8 RNF122 RNF139	6.90e-05	298	86	8	PS50089
Domain	LDLRA_1	LRP1 LRP2 CORIN SORL1	6.99e-05	48	86	4	PS01209
Domain	LDLRA_2	LRP1 LRP2 CORIN SORL1	7.58e-05	49	86	4	PS50068
Domain	LDrepeatLR_classA_rpt	LRP1 LRP2 CORIN SORL1	7.58e-05	49	86	4	IPR002172
Domain	LDLa	LRP1 LRP2 CORIN SORL1	7.58e-05	49	86	4	SM00192
Domain	RING	AMFR RNF7 RNF31 MYCBP2 RNFT1 RNF8 RNF122 RNF139	8.12e-05	305	86	8	SM00184
Domain	zf-RING_2	AMFR MYCBP2 RNF122 RNF139	9.58e-05	52	86	4	PF13639
Domain	EGF	MEGF8 PAMR1 LRP1 LRP2 LAMA4 ADAM11 SORL1	1.05e-04	235	86	7	SM00181
Domain	Znf_RING	AMFR RNF7 RNF31 MYCBP2 RNFT1 RNF8 RNF122 RNF139	1.29e-04	326	86	8	IPR001841
Domain	EGF-like_dom	MEGF8 PAMR1 LRP1 LRP2 LAMA4 ADAM11 SORL1	1.51e-04	249	86	7	IPR000742
Domain	TRAF-like	FBXO40 FBXO30 SIAH3	1.78e-04	24	86	3	IPR008974
Domain	ZF_RANBP2_1	TEX13C RNF31 ZRANB1	1.78e-04	24	86	3	PS01358
Domain	Znf_RanBP2	TEX13C RNF31 ZRANB1	2.01e-04	25	86	3	IPR001876
Domain	-	AMFR RNF7 MYCBP2 ZFYVE21 RNFT1 RNF8 RNF122 RNF139 UBR7	2.21e-04	449	86	9	3.30.40.10
Domain	Znf_RING/FYVE/PHD	AMFR RNF7 MYCBP2 ZFYVE21 RNFT1 RNF8 RNF122 RNF139 UBR7	2.60e-04	459	86	9	IPR013083
Domain	WxxW_domain	MUC2 MUC5AC	3.11e-04	6	86	2	IPR025155
Domain	Mucin2_WxxW	MUC2 MUC5AC	3.11e-04	6	86	2	PF13330
Domain	EGF_LAM_2	MEGF8 LAMA4 LAMB3	3.50e-04	30	86	3	PS50027
Domain	EGF_LAM_1	MEGF8 LAMA4 LAMB3	3.50e-04	30	86	3	PS01248
Domain	ZF_RING_1	AMFR RNF31 MYCBP2 RNFT1 RNF8 RNF122 RNF139	3.90e-04	291	86	7	PS00518
Domain	Anoct_dimer	ANO6 ANO5	4.34e-04	7	86	2	PF16178
Domain	Anoct_dimer	ANO6 ANO5	4.34e-04	7	86	2	IPR032394
Domain	Laminin_EGF	MEGF8 LAMA4 LAMB3	5.55e-04	35	86	3	PF00053
Domain	EGF_Lam	MEGF8 LAMA4 LAMB3	5.55e-04	35	86	3	SM00180
Domain	zf-C3HC4	AMFR RNF7 RNFT1 RNF8 RNF122 RNF139	5.75e-04	223	86	6	PF00097
Domain	Laminin_EGF	MEGF8 LAMA4 LAMB3	7.08e-04	38	86	3	IPR002049
Domain	Integin_beta_N	MEGF8 ITGB3	7.39e-04	9	86	2	IPR033760
Domain	PSI_integrin	MEGF8 ITGB3	7.39e-04	9	86	2	PF17205
Domain	EGF_3	MEGF8 PAMR1 LRP1 LRP2 ADAM11 SORL1	7.56e-04	235	86	6	PS50026
Domain	-	LRP1 LRP2 SORL1	7.64e-04	39	86	3	2.120.10.30
Domain	-	THOC1 TNFRSF25 NLRP8 NLRP13	8.96e-04	93	86	4	1.10.533.10
Domain	-	TEX13C ZRANB1	9.21e-04	10	86	2	4.10.1060.10
Domain	Anoctamin	ANO6 ANO5	9.21e-04	10	86	2	PF04547
Domain	Anoctamin	ANO6 ANO5	9.21e-04	10	86	2	IPR007632
Domain	Tyr_kinase_rcpt_2_CS	IGF1R NTRK3	1.12e-03	11	86	2	IPR002011
Domain	DEATH-like_dom	THOC1 TNFRSF25 NLRP8 NLRP13	1.13e-03	99	86	4	IPR011029
Domain	Znf_C3HC4_RING-type	AMFR RNFT1 RNF8 RNF122 RNF139	1.19e-03	172	86	5	IPR018957
Domain	6-blade_b-propeller_TolB-like	LRP1 LRP2 SORL1	1.24e-03	46	86	3	IPR011042
Domain	TIL	MUC2 MUC5AC	1.34e-03	12	86	2	PF01826
Domain	RECEPTOR_TYR_KIN_II	IGF1R NTRK3	1.34e-03	12	86	2	PS00239
Domain	Znf_TRAF	FBXO40 FBXO30	1.34e-03	12	86	2	IPR001293
Domain	C8	MUC2 MUC5AC	1.34e-03	12	86	2	PF08742
Domain	Unchr_dom_Cys-rich	MUC2 MUC5AC	1.58e-03	13	86	2	IPR014853
Domain	C8	MUC2 MUC5AC	1.58e-03	13	86	2	SM00832
Domain	ZF_TRAF	FBXO40 FBXO30	1.58e-03	13	86	2	PS50145
Domain	-	FBXO40 FBXO30	1.84e-03	14	86	2	3.90.890.10
Domain	SIAH-type	FBXO40 FBXO30	2.41e-03	16	86	2	IPR013323
Domain	VWD	MUC2 MUC5AC	2.41e-03	16	86	2	SM00216
Domain	VWF_type-D	MUC2 MUC5AC	2.41e-03	16	86	2	IPR001846
Domain	VWFD	MUC2 MUC5AC	2.41e-03	16	86	2	PS51233
Domain	VWD	MUC2 MUC5AC	2.41e-03	16	86	2	PF00094
Domain	EGF_CA	MEGF8 PAMR1 LRP1 LRP2	2.44e-03	122	86	4	SM00179
Domain	EGF-like_Ca-bd_dom	MEGF8 PAMR1 LRP1 LRP2	2.58e-03	124	86	4	IPR001881
Domain	EGF_extracell	LRP2 ADAM11 ITGB3	2.67e-03	60	86	3	IPR013111
Domain	EGF_2	LRP2 ADAM11 ITGB3	2.67e-03	60	86	3	PF07974
Domain	EGF	PAMR1 LRP1 LRP2 ITGB3	2.74e-03	126	86	4	PF00008
Domain	CTCK_1	MUC2 MUC5AC	3.06e-03	18	86	2	PS01185
Domain	VWC_out	MUC2 MUC5AC	3.41e-03	19	86	2	SM00215
Domain	PDEase	PDE7A PDE7B	3.41e-03	19	86	2	IPR023088
Domain	FRI	SFRP1 CORIN	3.77e-03	20	86	2	SM00063
Domain	PDEase_I	PDE7A PDE7B	4.16e-03	21	86	2	PF00233
Domain	-	SFRP1 CORIN	4.16e-03	21	86	2	1.10.2000.10
Domain	PDEASE_I	PDE7A PDE7B	4.16e-03	21	86	2	PS00126
Domain	PDEase_CS	PDE7A PDE7B	4.16e-03	21	86	2	IPR023174
Domain	zf-RanBP	RNF31 ZRANB1	4.56e-03	22	86	2	PF00641
Domain	DAPIN	NLRP8 NLRP13	4.56e-03	22	86	2	PS50824
Domain	PYRIN	NLRP8 NLRP13	4.56e-03	22	86	2	PF02758
Domain	DAPIN	NLRP8 NLRP13	4.56e-03	22	86	2	IPR004020
Domain	TNFR_c6	TNFRSF25 LTBR	4.56e-03	22	86	2	PF00020
Domain	PYRIN	NLRP8 NLRP13	4.56e-03	22	86	2	SM01289
Domain	-	PDE7A PDE7B	4.56e-03	22	86	2	1.10.1300.10
Domain	CT	MUC2 MUC5AC	4.56e-03	22	86	2	SM00041
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	CFH THADA IGF1R ADSL MEGF8 MYCBP2 ANO6 RNFT1 LRP1 ARFGEF2 LAMA4 LAMB3 PLAUR TWSG1 LTBR TANGO6 SORL1	1.30e-08	1201	91	17	35696571
Pubmed	Interaction of the apolipoprotein E receptors low density lipoprotein receptor-related protein and sorLA/LR11.	LRP1 LRP2 SORL1	1.73e-07	5	91	3	19047013
Pubmed	Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.	AMFR IGF1R NTRK3 LRP1 LRP2 ITGB3	2.82e-07	101	91	6	23382219
Pubmed	Development of a monoclonal anti-ADAMTS-5 antibody that specifically blocks the interaction with LRP1.	LRP1 ADAMTS5	6.77e-06	2	91	2	28306378
Pubmed	The soluble form of LR11 protein is a regulator of hypoxia-induced, urokinase-type plasminogen activator receptor (uPAR)-mediated adhesion of immature hematological cells.	PLAUR SORL1	6.77e-06	2	91	2	23486467
Pubmed	uPAR isoform 2 forms a dimer and induces severe kidney disease in mice.	PLAUR ITGB3	6.77e-06	2	91	2	30730305
Pubmed	LRP-1-mediated endocytosis regulates extracellular activity of ADAMTS-5 in articular cartilage.	LRP1 ADAMTS5	6.77e-06	2	91	2	23064555
Pubmed	Mucolytic activity of bacterial and human chitinases.	MUC2 MUC5AC	6.77e-06	2	91	2	17321686
Pubmed	Altered expression of MUC2 and MUC5AC in progression of colorectal carcinoma.	MUC2 MUC5AC	6.77e-06	2	91	2	20731025
Pubmed	LR11, an LDL receptor gene family member, is a novel regulator of smooth muscle cell migration.	PLAUR SORL1	6.77e-06	2	91	2	14764453
Pubmed	Choroid plexus megalin is involved in neuroprotection by serum insulin-like growth factor I.	IGF1R LRP2	6.77e-06	2	91	2	16306401
Pubmed	Negative regulation of urokinase receptor activity by a GPI-specific phospholipase C in breast cancer cells.	GDPD2 PLAUR	6.77e-06	2	91	2	28849762
Pubmed	Studies of mucus in mouse stomach, small intestine, and colon. II. Gastrointestinal mucus proteome reveals Muc2 and Muc5ac accompanied by a set of core proteins.	MUC2 MUC5AC	6.77e-06	2	91	2	23832517
Pubmed	Studies of mucus in mouse stomach, small intestine, and colon. III. Gastrointestinal Muc5ac and Muc2 mucin O-glycan patterns reveal a regiospecific distribution.	MUC2 MUC5AC	6.77e-06	2	91	2	23832516
Pubmed	Intestinal MUC2 and gastric M1/MUC5AC in preneoplastic lesions induced by 1,2-dimethylhydrazine in rat: a sequential analysis.	MUC2 MUC5AC	6.77e-06	2	91	2	17203232
Pubmed	LRP1 regulates remodeling of the extracellular matrix by fibroblasts.	LRP1 PLAUR	6.77e-06	2	91	2	19699300
Pubmed	Endocytic Protein Defects in the Neural Crest Cell Lineage and Its Pathway Are Associated with Congenital Heart Defects.	LRP1 LRP2	6.77e-06	2	91	2	34445520
Pubmed	Direct binding of occupied urokinase receptor (uPAR) to LDL receptor-related protein is required for endocytosis of uPAR and regulation of cell surface urokinase activity.	LRP1 PLAUR	6.77e-06	2	91	2	11359936
Pubmed	Methylation status of promoters and expression of MUC2 and MUC5AC mucins in pancreatic cancer cells.	MUC2 MUC5AC	6.77e-06	2	91	2	12527922
Pubmed	Clathrin and LRP-1-independent constitutive endocytosis and recycling of uPAR.	LRP1 PLAUR	6.77e-06	2	91	2	19008962
Pubmed	In vivo glycosylation of mucin tandem repeats.	MUC2 MUC5AC	6.77e-06	2	91	2	11445551
Pubmed	Temporal analysis of goblet cells and mucin gene expression in murine models of allergic asthma.	MUC2 MUC5AC	6.77e-06	2	91	2	14594655
Pubmed	Abnormal subcellular distribution of mature MUC2 and de novo MUC5AC mucins in adenomas of the rectum: immunohistochemical detection using non-VNTR antibodies to MUC2 and MUC5AC peptide.	MUC2 MUC5AC	6.77e-06	2	91	2	12820724
Pubmed	A comprehensive framework of E2-RING E3 interactions of the human ubiquitin-proteasome system.	AMFR RNFT1 RNF8 RNF122 RNF139	1.52e-05	118	91	5	19690564
Pubmed	Low density lipoprotein receptor-related protein 1 (LRP1)-mediated endocytic clearance of a disintegrin and metalloproteinase with thrombospondin motifs-4 (ADAMTS-4): functional differences of non-catalytic domains of ADAMTS-4 and ADAMTS-5 in LRP1 binding.	LRP1 ADAMTS5	2.03e-05	3	91	2	24474687
Pubmed	Differences in the expression of mucins in various forms of cystitis glandularis.	MUC2 MUC5AC	2.03e-05	3	91	2	17659847
Pubmed	Cadherin-catenin adhesion system and mucin expression: a comparison between young and older patients with gastric carcinoma.	MUC2 MUC5AC	2.03e-05	3	91	2	18825309
Pubmed	Downstream of tyrosine kinase/docking protein 6, as a novel substrate of tropomyosin-related kinase C receptor, is involved in neurotrophin 3-mediated neurite outgrowth in mouse cortex neurons.	DOK6 NTRK3	2.03e-05	3	91	2	20565848
Pubmed	Adenomatous and foveolar gastric dysplasia: distinct patterns of mucin expression and background intestinal metaplasia.	MUC2 MUC5AC	2.03e-05	3	91	2	18300795
Pubmed	Expression of aberrant mucins in lobular carcinoma with histiocytoid feature of the breast.	MUC2 MUC5AC	2.03e-05	3	91	2	17333267
Pubmed	Dimerization leads to changes in APP (amyloid precursor protein) trafficking mediated by LRP1 and SorLA.	LRP1 SORL1	2.03e-05	3	91	2	28799085
Pubmed	Mucin gene polymorphisms in otitis media patients.	MUC2 MUC5AC	2.03e-05	3	91	2	19718741
Pubmed	Gene expression profiling of colorectal mucinous adenocarcinomas.	MUC2 MUC5AC	2.03e-05	3	91	2	20485009
Pubmed	uPAR enhances malignant potential of triple-negative breast cancer by directly interacting with uPA and IGF1R.	IGF1R PLAUR	2.03e-05	3	91	2	27502396
Pubmed	THADA fusion is a mechanism of IGF2BP3 activation and IGF1R signaling in thyroid cancer.	THADA IGF1R	2.03e-05	3	91	2	28193878
Pubmed	Factor H binds to platelet integrin alphaIIbbeta3.	CFH ITGB3	2.03e-05	3	91	2	18979363
Pubmed	Clinicopathological and prognostic significance of MUC-2, MUC-4 and MUC-5AC expression in japanese gastric carcinomas.	MUC2 MUC5AC	2.03e-05	3	91	2	23464473
Pubmed	Meconium ileus in cystic fibrosis is not linked to central repetitive region length variation in MUC1, MUC2, and MUC5AC.	MUC2 MUC5AC	2.03e-05	3	91	2	24920497
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	UNC13B CFH TNFRSF25 DMXL2 PDE7A MYCBP2 ZNF451 LRP1 LRP2 ARFGEF2 PLAUR TRIP12 DOP1B	2.97e-05	1285	91	13	35914814
Pubmed	Mannose 6-phosphate/insulin-like growth factor 2 receptor limits cell invasion by controlling alphaVbeta3 integrin expression and proteolytic processing of urokinase-type plasminogen activator receptor.	PLAUR ITGB3	4.05e-05	4	91	2	19037107
Pubmed	Dependence receptors: the trophic theory revisited.	IGF1R NTRK3	4.05e-05	4	91	2	21139137
Pubmed	Disabled-2 is essential for endodermal cell positioning and structure formation during mouse embryogenesis.	LRP1 LRP2	4.05e-05	4	91	2	12413896
Pubmed	Increased expression of MUC5AC and MUC5B promoting bacterial biofilm formation in chronic rhinosinusitis patients.	MUC2 MUC5AC	4.05e-05	4	91	2	25638393
Pubmed	Expression of MUC1, MUC2, MUC5AC and MUC5B in mucinous lesions of the breast.	MUC2 MUC5AC	4.05e-05	4	91	2	22269464
Pubmed	Notch3 and Jagged2 contribute to gastric cancer development and to glandular differentiation associated with MUC2 and MUC5AC expression.	MUC2 MUC5AC	4.05e-05	4	91	2	22691042
Pubmed	Munc13-2-/- baseline secretion defect reveals source of oligomeric mucins in mouse airways.	UNC13B MUC5AC	4.05e-05	4	91	2	18258655
Pubmed	Identification of the low density lipoprotein receptor-related protein (LRP) as an endocytic receptor for thrombospondin-1.	LRP1 LRP2	4.05e-05	4	91	2	7775583
Pubmed	Interleukin-1beta induces MUC2 and MUC5AC synthesis through cyclooxygenase-2 in NCI-H292 cells.	MUC2 MUC5AC	4.05e-05	4	91	2	12391274
Pubmed	Expression of MUC2, MUC5AC, MUC5B, and MUC6 mucins in colorectal cancers and their association with the CpG island methylator phenotype.	MUC2 MUC5AC	4.05e-05	4	91	2	23807779
Pubmed	A tripartite complex composed of ETV6-NTRK3, IRS1 and IGF1R is required for ETV6-NTRK3-mediated membrane localization and transformation.	IGF1R NTRK3	4.05e-05	4	91	2	21804605
Pubmed	Associations between the expression of mucins (MUC1, MUC2, MUC5AC and MUC6) and clinicopathologic parameters of human breast carcinomas.	MUC2 MUC5AC	4.05e-05	4	91	2	33154304
Pubmed	The direct binding of insulin-like growth factor-1 (IGF-1) to integrin alphavbeta3 is involved in IGF-1 signaling.	IGF1R ITGB3	4.05e-05	4	91	2	19578119
Pubmed	Gastric mucin expression in first-degree relatives of gastric cancer patients.	MUC2 MUC5AC	4.05e-05	4	91	2	24901817
Pubmed	Evaluation of MUC1, MUC2, MUC5AC, and MUC6 Expression Differences in Lung Adenocarcinoma Subtypes by Using a Final Immunoreactivity Score (FIRS).	MUC2 MUC5AC	4.05e-05	4	91	2	36367122
Pubmed	Expression and function of the urokinase type plasminogen activator during mouse hemochorial placental development.	LRP1 PLAUR	4.05e-05	4	91	2	9733098
Pubmed	Epigenetic regulation (DNA methylation, histone modifications) of the 11p15 mucin genes (MUC2, MUC5AC, MUC5B, MUC6) in epithelial cancer cells.	MUC2 MUC5AC	4.05e-05	4	91	2	17471237
Pubmed	The mouse secreted gel-forming mucin gene cluster.	MUC2 MUC5AC	4.05e-05	4	91	2	14984930
Pubmed	Trabid inhibits hepatocellular carcinoma growth and metastasis by cleaving RNF8-induced K63 ubiquitination of Twist1.	RNF8 ZRANB1	4.05e-05	4	91	2	29748601
Pubmed	Effects of the Helicobacter pylori Virulence Factor CagA and Ammonium Ion on Mucins in AGS Cells.	MUC2 MUC5AC	4.05e-05	4	91	2	29869461
Pubmed	[Expression and clinical significance of Mucin and E-cadherin in colorectal tumors].	MUC2 MUC5AC	4.05e-05	4	91	2	17991319
Pubmed	Mucins in neoplastic spectrum of colorectal polyps: can they provide predictions?	MUC2 MUC5AC	4.05e-05	4	91	2	20929551
Pubmed	Role of Formyl Peptide Receptors and β-Arrestin-1 in suPAR Signal Transduction in Mouse Podocytes: Interactions with αVβ3-Integrin.	PLAUR ITGB3	4.05e-05	4	91	2	38247863
Pubmed	Role of apolipoprotein E receptors in regulating the differential in vivo neurotrophic effects of apolipoprotein E.	LRP1 LRP2	4.05e-05	4	91	2	11421580
Pubmed	Stromal factors SDF1α, sFRP1, and VEGFD induce dopaminergic neuron differentiation of human pluripotent stem cells.	SFRP1 VEGFD	4.05e-05	4	91	2	22535492
Pubmed	MUC1, MUC2, MUC5AC, and MUC6 in colorectal cancer: expression profiles and clinical significance.	MUC2 MUC5AC	4.05e-05	4	91	2	27298226
Pubmed	A tripartite complex of suPAR, APOL1 risk variants and αvβ3 integrin on podocytes mediates chronic kidney disease.	PLAUR ITGB3	4.05e-05	4	91	2	28650456
Pubmed	PGE(2) induces MUC2 and MUC5AC expression in human intrahepatic biliary epithelial cells via EP4/p38MAPK activation.	MUC2 MUC5AC	4.05e-05	4	91	2	23619266
Pubmed	Mucin expression profile in Barrett's, dysplasia, adenocarcinoma sequence in the esophagus.	MUC2 MUC5AC	4.05e-05	4	91	2	17401217
Pubmed	MMP-13 is constitutively produced in human chondrocytes and co-endocytosed with ADAMTS-5 and TIMP-3 by the endocytic receptor LRP1.	LRP1 ADAMTS5	4.05e-05	4	91	2	27084377
Pubmed	Characterization of mouse muc6 and evidence of conservation of the gel-forming mucin gene cluster between human and mouse.	MUC2 MUC5AC	4.05e-05	4	91	2	12676567
Pubmed	The pro-neurotrophin receptor sortilin is a major neuronal apolipoprotein E receptor for catabolism of amyloid-β peptide in the brain.	LRP1 SORL1	4.05e-05	4	91	2	23283348
Pubmed	Alpha-enolase (ENO1) controls alpha v/beta 3 integrin expression and regulates pancreatic cancer adhesion, invasion, and metastasis.	PLAUR ITGB3	4.05e-05	4	91	2	28086938
Pubmed	Expression profile of mucins (MUC1, MUC2, MUC5AC, and MUC6) in ovarian mucinous tumours: changes in expression from benign to malignant tumours.	MUC2 MUC5AC	4.05e-05	4	91	2	25298197
Pubmed	Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.	CFH SFRP1 PAMR1 LAMA4 ADAMTS5 VEGFD	4.97e-05	248	91	6	24006456
Pubmed	Cul3-KLHL20 E3 ubiquitin ligase plays a key role in the arms race between HIV-1 Nef and host SERINC5 restriction.	AMFR MYCBP2 TRIP12	5.41e-05	28	91	3	35474067
Pubmed	Polymorphism of human mucin genes in chest disease: possible significance of MUC2.	MUC2 MUC5AC	6.74e-05	5	91	2	11062147
Pubmed	Cloning and characterization of a novel UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase, pp-GalNAc-T14.	MUC2 MUC5AC	6.74e-05	5	91	2	12507512
Pubmed	Molecular cloning and characterization of a novel member of the UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase family, pp-GalNAc-T12.	MUC2 MUC5AC	6.74e-05	5	91	2	12135769
Pubmed	Degradation of internalized αvβ5 integrin is controlled by uPAR bound uPA: effect on β1 integrin activity and α-SMA stress fiber assembly.	PLAUR ITGB3	6.74e-05	5	91	2	22470492
Pubmed	High level of cannabinoid receptor 1, absence of regulator of G protein signalling 13 and differential expression of Cyclin D1 in mantle cell lymphoma.	RGS13 SORL1	6.74e-05	5	91	2	12970790
Pubmed	Differential expression of MUC genes in endometrial and cervical tissues and tumors.	MUC2 MUC5AC	6.74e-05	5	91	2	16188033
Pubmed	MUC1, MUC2, MUC4, MUC5AC and MUC6 expression in the progression of prostate cancer.	MUC2 MUC5AC	6.74e-05	5	91	2	16475027
Pubmed	Interaction of coagulation factor VIII with members of the low-density lipoprotein receptor family follows common mechanism and involves consensus residues within the A2 binding site 484-509.	LRP1 LRP2	6.74e-05	5	91	2	18685438
Pubmed	ApoER2 is endocytosed by a clathrin-mediated process involving the adaptor protein Dab2 independent of its Rafts' association.	LRP1 LRP2	6.74e-05	5	91	2	16101684
Pubmed	Sterol-induced degradation of HMG CoA reductase depends on interplay of two Insigs and two ubiquitin ligases, gp78 and Trc8.	AMFR RNF139	6.74e-05	5	91	2	22143767
Pubmed	Modification of kidney barrier function by the urokinase receptor.	PLAUR ITGB3	6.74e-05	5	91	2	18084301
Pubmed	Overexpression of malignancy-associated laminins and laminin receptors by angiotropic human melanoma cells in a chick chorioallantoic membrane model.	LAMA4 ITGB3	6.74e-05	5	91	2	19469865
Pubmed	Apolipoprotein A-V interaction with members of the low density lipoprotein receptor gene family.	LRP1 SORL1	6.74e-05	5	91	2	17326667
Pubmed	SHARPIN at the nexus of integrin, immune, and inflammatory signaling in human platelets.	RNF31 ITGB3	6.74e-05	5	91	2	30804189
Pubmed	pS2/TFF1 interacts directly with the VWFC cysteine-rich domains of mucins.	MUC2 MUC5AC	6.74e-05	5	91	2	10611155
Pubmed	Divergent expression of MUC5AC, MUC6, MUC2, CD10, and CDX-2 in dysplasia and intramucosal adenocarcinomas with intestinal and foveolar morphology: is this evidence of distinct gastric and intestinal pathways to carcinogenesis in Barrett Esophagus?	MUC2 MUC5AC	6.74e-05	5	91	2	22261707
Pubmed	A neurogenomics approach to gene expression analysis in the developing brain.	CFH SLCO1C1 ZNF451 CNMD TRIP12	8.71e-05	170	91	5	15582152
Pubmed	Endocytic receptor LRP together with tPA and PAI-1 coordinates Mac-1-dependent macrophage migration.	LRP1 PLAUR	1.01e-04	6	91	2	16601674
Pubmed	Expression of Muc19/Smgc gene products during murine sublingual gland development: cytodifferentiation and maturation of salivary mucous cells.	MUC2 MUC5AC	1.01e-04	6	91	2	19110483
Pubmed	Interaction of cytosolic adaptor proteins with neuronal apolipoprotein E receptors and the amyloid precursor protein.	LRP1 LRP2	1.01e-04	6	91	2	9837937
Pubmed	Expression of mucin core proteins, trefoil factors, APC and p21 in subsets of colorectal polyps and cancers suggests a distinct pathway of pathogenesis of mucinous carcinoma of the colorectum.	MUC2 MUC5AC	1.01e-04	6	91	2	16142311
Pubmed	Biosynthesis of gastrokine-2 in the human gastric mucosa: restricted spatial expression along the antral gland axis and differential interaction with TFF1, TFF2 and mucins.	MUC2 MUC5AC	1.01e-04	6	91	2	17982272
Pubmed	Identification and characterization of TMEM16E and TMEM16F genes in silico.	ANO6 ANO5	1.01e-04	6	91	2	15067359
Pubmed	Direct integrin binding to insulin-like growth factor-2 through the C-domain is required for insulin-like growth factor receptor type 1 (IGF1R) signaling.	IGF1R ITGB3	1.01e-04	6	91	2	28873464
Pubmed	Ancient ubiquitous protein-1 mediates sterol-induced ubiquitination of 3-hydroxy-3-methylglutaryl CoA reductase in lipid droplet-associated endoplasmic reticulum membranes.	AMFR RNF139	1.01e-04	6	91	2	23223569
Cytoband	2p23.2	SPDYA WDR43	2.99e-04	13	91	2	2p23.2
GeneFamily	Ring finger proteins	AMFR RNF7 RNF31 RNFT1 RNF8 RNF122 RNF139	5.72e-05	275	65	7	58
GeneFamily	Receptor Tyrosine Kinases\|CD molecules	IGF1R NTRK3 RYK	3.98e-04	40	65	3	321
GeneFamily	Anoctamins	ANO6 ANO5	5.62e-04	10	65	2	865
GeneFamily	Laminin subunits	LAMA4 LAMB3	8.21e-04	12	65	2	626
GeneFamily	Low density lipoprotein receptors	LRP1 LRP2	9.68e-04	13	65	2	634
GeneFamily	Zinc fingers RANBP2-type \|RNA binding motif containing	RNF31 ZRANB1	2.56e-03	21	65	2	89
GeneFamily	CD molecules\|Mucins	MUC2 MUC5AC	2.56e-03	21	65	2	648
GeneFamily	Phosphodiesterases	PDE7A PDE7B	3.34e-03	24	65	2	681
GeneFamily	NLR family	NLRP8 NLRP13	3.62e-03	25	65	2	666
GeneFamily	Pyrin domain containing\|Pyrin and HIN domain family	NLRP8 NLRP13	3.62e-03	25	65	2	994
GeneFamily	CD molecules\|Tumor necrosis factor receptor superfamily\|Death inducing signaling complex	TNFRSF25 LTBR	4.85e-03	29	65	2	782
GeneFamily	Cyclins\|F-boxes other	FBXO40 FBXO30	8.66e-03	39	65	2	560
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CFH SFRP1 PAMR1 LRP1 LAMA4 SPDYA PTGFR PDE7B	4.65e-09	186	91	8	f07e0c0d9c80ac9d8d679950e7d0c812becb85a3
ToppCell	facs-Trachea-nan-3m-Mesenchymal-fibroblast\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH PAMR1 LRP1 LAMA4 TWSG1 ADAMTS5 PTGFR	1.70e-07	198	91	7	0dc7d59a07428a7b7e8bdc81f0e2417dd4ce3cf2
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CFH SFRP1 PAMR1 LRP1 LAMA4 ADAMTS5 VEGFD	1.82e-07	200	91	7	6f7f015b5fa1f52374f2c7d9ba339012395eda5f
ToppCell	Control_saline-Mesenchymal_myocytic-Myofibroblastic\|Control_saline / Treatment groups by lineage, cell group, cell type	SFRP1 PAMR1 LRP1 LAMA4 ADAMTS5 PTGFR PDE7B	1.82e-07	200	91	7	9d5b3c2dcfa55d50acc2ce2c319d51aa525d4cd1
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-fibroblastic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CFH SFRP1 PAMR1 LRP1 LAMA4 ADAMTS5 VEGFD	1.82e-07	200	91	7	3a164e3971bcd62b148b813171c103adb81f972e
ToppCell	P07-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CFH SFRP1 LRP1 ADAMTS5 VEGFD PTGFR	2.15e-06	184	91	6	01257e5c12e38b849fd3d9496c43ded666249ba5
ToppCell	droplet-Kidney-nan-21m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH LRP1 LAMA4 ADAMTS5 MDFIC2 VEGFD	2.15e-06	184	91	6	3bffadb0cb2e0d825bdb6cfc5d23f5436cbc3efd
ToppCell	droplet-Kidney-nan-21m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH LRP1 LAMA4 ADAMTS5 MDFIC2 VEGFD	2.22e-06	185	91	6	33cc0e9d8b54cb7408b51235f2a70e044ebae04d
ToppCell	droplet-Kidney-nan-21m-Mesenchymal-Stroma____fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH LRP1 LAMA4 ADAMTS5 MDFIC2 VEGFD	2.22e-06	185	91	6	9954fc85b183c1cc45c3c24e3dadc7984ee6f649
ToppCell	facs-Lung-18m-Mesenchymal\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH PAMR1 LRP1 LAMA4 TWSG1 VEGFD	2.52e-06	189	91	6	bdf8db938aa0863c4fed6fa99dcffd63c8c20c31
ToppCell	facs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH SFRP1 PAMR1 LRP1 ADAMTS5 PTGFR	2.67e-06	191	91	6	2b73fcd592d16cae8ded5e45c8fbf2d9adc8caad
ToppCell	facs-Lung-nan-3m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH PAMR1 LRP1 LAMA4 ADAMTS5 PTGFR	2.75e-06	192	91	6	a2c31390da4962bda9a936470b0b68fa1f5d47d1
ToppCell	facs-Lung-nan-3m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH PAMR1 LRP1 LAMA4 ADAMTS5 PTGFR	2.75e-06	192	91	6	eeab1cef7c36ae824381952c5b2c982368c379fd
ToppCell	facs-Lung-3m-Mesenchymal\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH PAMR1 LRP1 LAMA4 TWSG1 VEGFD	2.75e-06	192	91	6	8df15085b35b86f39debd933284cb703c5dd63c2
ToppCell	facs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH SFRP1 PAMR1 LRP1 ADAMTS5 PTGFR	2.75e-06	192	91	6	011634a24b0c61d9b463fe755502edbc5cd70b7a
ToppCell	(2)_5-FU-(2)_LEPR+_perivascular_cells_and_VE-Cad+_vascular_cells_(mixed)\|World / Stress and Cell class	CFH EPHX2 SFRP1 LRP1 LAMA4 LARS2	2.84e-06	193	91	6	f31398dad5321a7bcb27e208bd73630e9756e897
ToppCell	PND28-Mesenchymal-Mesenchymal_structural\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFH PAMR1 LRP1 LAMA4 TWSG1 VEGFD	2.84e-06	193	91	6	ec81c1afdae2e0433a22c8c1fa1c6232526ff7e7
ToppCell	facs-Heart-RV-3m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH SFRP1 LRP1 TWSG1 ADAMTS5 RYK	2.84e-06	193	91	6	76f0f8569255d6cdf1e3b8e954cae72e71f87157
ToppCell	facs-Lung-EPCAM-18m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH SFRP1 PAMR1 LRP1 ADAMTS5 PTGFR	2.84e-06	193	91	6	92048d2e9e43513e6185e09553be3ee47d7e5207
ToppCell	facs-Lung-nan-3m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH PAMR1 LRP1 LAMA4 TWSG1 ADAMTS5	2.84e-06	193	91	6	d9c20a092b507c43fcf7ccb04073fecd27d1749c
ToppCell	facs-Lung-24m-Mesenchymal-fibroblast-adventitial_fibroblast\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH SFRP1 PAMR1 LRP1 ADAMTS5 PTGFR	2.84e-06	193	91	6	e27885a9e1a2a3e165c5366d4cfcda05c5454483
ToppCell	facs-Lung-EPCAM-18m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH SFRP1 PAMR1 LRP1 ADAMTS5 PTGFR	2.84e-06	193	91	6	ac088c8f27b5b1888610e461ff45870ca60da886
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFH PAMR1 LRP1 LAMA4 TWSG1 VEGFD	2.84e-06	193	91	6	30481fb01c7acf85beae10213f038da86bed6777
ToppCell	droplet-Trachea-nan-3m-Mesenchymal-mesenchymal_progenitor_cell\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH PAMR1 LRP1 LAMA4 VEGFD PTGFR	2.92e-06	194	91	6	3d25d6ebec8d1b6001f602257cd15b3ba04cf0c1
ToppCell	droplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH PAMR1 LRP1 LAMA4 VEGFD PTGFR	2.92e-06	194	91	6	ff19fb5bc7feae3e774ef4ab720beb9dec219f45
ToppCell	facs-Lung-3m-Mesenchymal-myofibroblast-myofibroblast_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PAMR1 NTRK3 LAMA4 CORIN TWSG1 PDE7B	3.01e-06	195	91	6	c6bb16c0076639c6ddef1a15d8cba44bc29c077d
ToppCell	facs-Lung-3m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PAMR1 NTRK3 LAMA4 CORIN TWSG1 PDE7B	3.01e-06	195	91	6	ea89f80d3d7e9f737442f7c1aa1791d277ffc90c
ToppCell	PND28-Mesenchymal\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFH PAMR1 LRP1 LAMA4 TWSG1 VEGFD	3.10e-06	196	91	6	119265efd2219f328d8152dbee52af8327aec89c
ToppCell	facs-Lung-nan\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAMR1 LRP1 LAMA4 TWSG1 ADAMTS5 LARS2	3.10e-06	196	91	6	b05f77f3990b662682ffeaf0e4c2fb190e0a6e65
ToppCell	facs-Lung-nan-3m\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAMR1 LRP1 LAMA4 TWSG1 ADAMTS5 LARS2	3.10e-06	196	91	6	787c6cd92035e0b1108c2c086c42a229016e476b
ToppCell	3'-Pediatric_IBD-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CFH SFRP1 LRP1 LAMA4 ADAMTS5 PTGFR	3.39e-06	199	91	6	6139687a3a5025cb98da4dba0183f95fcae3dc61
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CFH SFRP1 PAMR1 LRP1 LAMA4 ADAMTS5	3.48e-06	200	91	6	933b5b400e48a511ba0a056be1d33d3610b5f10d
ToppCell	Control_saline-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|Control_saline / Treatment groups by lineage, cell group, cell type	SFRP1 PAMR1 LAMA4 ADAMTS5 PTGFR PDE7B	3.48e-06	200	91	6	c5e051f1aac8dda376c342a9932785a23450e073
ToppCell	5'-Adult-SmallIntestine-Mesenchymal\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CFH SFRP1 PAMR1 LAMA4 ADAMTS5 VEGFD	3.48e-06	200	91	6	a637281d91e95734ee4f8510b3780e0272b16fda
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CFH SFRP1 PAMR1 LRP1 ADAMTS5 VEGFD	3.48e-06	200	91	6	cfea2f9d85646c9b722150551ff2e8fc4f6cc98a
ToppCell	3'-Adult-LargeIntestine-Mesenchymal-fibroblastic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CFH SFRP1 PAMR1 LRP1 LAMA4 ADAMTS5	3.48e-06	200	91	6	cbf6a6c3db88bac37bd084a3a914b12b3af524eb
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CFH PAMR1 NTRK3 LRP1 LAMA4	2.45e-05	168	91	5	4b2d29a7843bf45922038c093ca7ec0600756adc
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CFH PAMR1 NTRK3 LRP1 LAMA4	2.67e-05	171	91	5	5d31fc9b60329d4ae3c77e4ca679359d9314397d
ToppCell	343B-Fibroblasts-Fibroblast-H-\|343B / Donor, Lineage, Cell class and subclass (all cells)	SFRP1 PAMR1 LAMA4 ADAMTS5 PTGFR	2.90e-05	174	91	5	2627c3983009839fedbc5e3f628739dc026447f4
ToppCell	343B-Fibroblasts-Fibroblast-H\|343B / Donor, Lineage, Cell class and subclass (all cells)	SFRP1 PAMR1 LAMA4 ADAMTS5 PTGFR	2.90e-05	174	91	5	507a33e58f62e2b72f0bcc743e84dbd0bf705a15
ToppCell	tumor_Lymph_Node_/_Brain-Fibroblasts-COL13A1+_matrix_FBs\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	CFH LINC00473 PAMR1 LAMA4 ADAMTS5	3.07e-05	176	91	5	510f9a14dc1c151d24d079e0cc004cdf4f86336c
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CFH PAMR1 LRP1 LAMA4 ADAMTS5	3.50e-05	181	91	5	c6d2a13df3b74fade3b0c71e285b4c14c8e52413
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CFH PAMR1 LRP1 LAMA4 ADAMTS5	3.50e-05	181	91	5	c62b0a2422377ffadaab63edd538e87a06fa5017
ToppCell	facs-Lung-nan-3m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH LRP1 TWSG1 VEGFD FBXO30	3.60e-05	182	91	5	c557de6ccd327c46e0a5423cd9936d78e0abae5f
ToppCell	facs-Lung-nan-3m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH LRP1 TWSG1 VEGFD FBXO30	3.60e-05	182	91	5	dbe4b2557cf19e0682ed446f8397d3a1153642f0
ToppCell	droplet-Kidney-nan-21m-Epithelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMC1 NTRK3 CNMD GDPD2 ADAMTS5	3.69e-05	183	91	5	f55081068213cc1cdb2acad58ff10f6b48b44c72
ToppCell	facs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH PAMR1 LAMA4 ADAMTS5 VEGFD	3.89e-05	185	91	5	3cd0686a14e734a0f243070ab939adcb4c454478
ToppCell	facs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH PAMR1 LAMA4 ADAMTS5 VEGFD	3.89e-05	185	91	5	00258f458cbf6d36449db95528a6b5038d731d2d
ToppCell	facs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH PAMR1 LAMA4 ADAMTS5 VEGFD	3.89e-05	185	91	5	a94694e226856bc5b168464f52d76004145717a5
ToppCell	E17.5-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SFRP1 NTRK3 LRP1 ADAMTS5 VEGFD	3.89e-05	185	91	5	c85bba1210f1d389add3e40be9b96abac40cf8c1
ToppCell	CV-Moderate-7\|Moderate / Virus stimulation, Condition and Cluster	NBAS DMXL2 MYCBP2 WDR43 DOP1B	3.89e-05	185	91	5	a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCell	(2)_5-FU-(2)_LEPR+_perivascular_cells_and_VE-Cad+_vascular_cells_(mixed)\|(2)_5-FU / Stress and Cell class	CFH SFRP1 MYCBP2 LRP1 LARS2	4.09e-05	187	91	5	6bbf0f7fe203274dae8d582652f35cd3187c0065
ToppCell	droplet-Lung-18m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PAMR1 LAMA4 CORIN TWSG1 ADAMTS5	4.09e-05	187	91	5	8bd635abdee5d5a12a3f7bf74eab4282e8e40741
ToppCell	droplet-Lung-18m-Mesenchymal-myofibroblast-myofibroblast_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PAMR1 LAMA4 CORIN TWSG1 ADAMTS5	4.09e-05	187	91	5	3cb8cd7f7a4306ff74d1f7f9964014008ec1c6a0
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFH LRP2 PTGFR MUC5AC SORL1	4.09e-05	187	91	5	f5a202d5f8eb57b57d80815ce98774e04c387383
ToppCell	droplet-Lung-21m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EPHX2 SFRP1 PAMR1 NTRK3 CORIN	4.31e-05	189	91	5	cd42ce4aa217d0bd95e0cc0ba357bdfeb3e55a48
ToppCell	droplet-Lung-21m-Mesenchymal-myofibroblast-myofibroblast_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EPHX2 SFRP1 PAMR1 NTRK3 CORIN	4.31e-05	189	91	5	102501eee7760d5882dec41ea9d00147b3f4fb73
ToppCell	RV-04._Ventricular_Cardiomyocyte_I\|RV / Chamber and Cluster_Paper	FBXO40 PDE7A CORIN ANO5 GAB1	4.31e-05	189	91	5	9c1debd65c13d63fd4f3158917d621b44b714c26
ToppCell	droplet-Lung-immune-endo-depleted\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH PAMR1 LAMA4 TWSG1 VEGFD	4.31e-05	189	91	5	c3fb363bb0156ffb3367c200f548faebda64ab4a
ToppCell	droplet-Lung-immune-endo-depleted-3m\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH PAMR1 LAMA4 TWSG1 VEGFD	4.31e-05	189	91	5	2a2953f6b1b7d070d739dcaf7285fce6e097d9e4
ToppCell	droplet-Mammary_Gland-nan-21m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH PAMR1 LRP1 LAMA4 ADAMTS5	4.31e-05	189	91	5	bc54ffd7bd1627a36747a80ce5139e4a69928400
ToppCell	facs-Lung-18m-Mesenchymal-fibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH PAMR1 LRP1 TWSG1 VEGFD	4.31e-05	189	91	5	40cbd679dc0548bf5207e1b033c0597886ad6fe1
ToppCell	droplet-Lung-3m\|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH PAMR1 LAMA4 TWSG1 VEGFD	4.31e-05	189	91	5	5a636e952da9b1fd26aa17f7b129054f2da322b5
ToppCell	droplet-Lung-21m-Mesenchymal-myofibroblast\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EPHX2 SFRP1 PAMR1 NTRK3 CORIN	4.31e-05	189	91	5	6e83bf855d4771885b60bb8992df2f9b508eef97
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CFH PAMR1 NTRK3 LRP1 LAMA4	4.41e-05	190	91	5	efb757f11c2809e66ddb48a5c84f5433f111cb7c
ToppCell	droplet-Lung-immune-endo-depleted-3m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH PAMR1 LAMA4 TWSG1 VEGFD	4.41e-05	190	91	5	9cd147a174017ebda23cc47b6d4552d898acd092
ToppCell	facs-GAT-Fat-24m-Mesenchymal\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SFRP1 PAMR1 LRP1 ADAMTS5 VEGFD	4.41e-05	190	91	5	3720e64129f3f3268b1dc14031a76f41c38241c2
ToppCell	facs-GAT-Fat-24m-Mesenchymal-mesenchymal_progenitor\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SFRP1 PAMR1 LRP1 ADAMTS5 VEGFD	4.41e-05	190	91	5	73a50426f972f08f9bb525ad5c0b774187ab5d6a
ToppCell	droplet-Mammary_Gland-nan-21m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH PAMR1 LRP1 LAMA4 ADAMTS5	4.41e-05	190	91	5	f3ca94a31a35eed5fecf3c4b8c957e1bc4150158
ToppCell	facs-GAT-Fat-24m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SFRP1 PAMR1 LRP1 ADAMTS5 VEGFD	4.41e-05	190	91	5	b55cf1fb586b724295b7b038483249847bb344fc
ToppCell	droplet-Mammary_Gland-nan-21m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH PAMR1 LRP1 LAMA4 ADAMTS5	4.41e-05	190	91	5	c2cd1eb674162ee40502c3380b7245c85079c7ce
ToppCell	droplet-Heart-nan-3m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH SFRP1 LRP1 CORIN TWSG1	4.41e-05	190	91	5	96a92212ea3fb35fa3d0da495e504edc61c71c23
ToppCell	droplet-Lung-immune-endo-depleted-3m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH PAMR1 LAMA4 TWSG1 VEGFD	4.53e-05	191	91	5	a261f0738d974784bbdd60f23092bfbcca464459
ToppCell	droplet-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EPHX2 THADA SFRP1 SPDYA ADAMTS5	4.53e-05	191	91	5	b51e0f5d1b93f526160c904e9091313a5364f3a7
ToppCell	droplet-Limb_Muscle-nan-24m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH SFRP1 LRP1 ADAMTS5 VEGFD	4.53e-05	191	91	5	83d1915835df6f2eb23f87986d695e71398edb9d
ToppCell	droplet-Lung-30m-Mesenchymal-fibroblast\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SFRP1 PAMR1 LAMA4 ADAMTS5 VEGFD	4.53e-05	191	91	5	cd497abed9e00e4e0becd9dbc036c6e7a60ae791
ToppCell	droplet-Lung-immune-endo-depleted-3m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH PAMR1 LAMA4 TWSG1 VEGFD	4.53e-05	191	91	5	6594398cc8151c73696391a43ac110c10283dab1
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH SFRP1 CNMD LRP1 ADAMTS5	4.53e-05	191	91	5	1efb47743b6834b64cb0f61721ddbe875b1a66ca
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH LRP1 LAMA4 TWSG1 VEGFD	4.53e-05	191	91	5	997abf0cc5873bed0372c4a333ed307fa72774d2
ToppCell	droplet-Lung-1m-Mesenchymal\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH PAMR1 LAMA4 TWSG1 VEGFD	4.64e-05	192	91	5	01433bd4794b8bcc51fe4249124a0f4289b9d6e2
ToppCell	facs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SFRP1 LRP1 LAMA4 TWSG1 ADAMTS5	4.64e-05	192	91	5	671d4e1eee5aba03c43dbc98f4b51ce42b3df5d5
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH SFRP1 CNMD LRP1 ADAMTS5	4.64e-05	192	91	5	5e6f8206ee0b10cdba79a7c4a05452cb025a5512
ToppCell	facs-Trachea-3m-Mesenchymal-fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH PAMR1 LRP1 LAMA4 ADAMTS5	4.64e-05	192	91	5	321850b0f881420c2d57d3e825e365c82fa511ab
ToppCell	droplet-Kidney-KIDNEY-30m-Mesenchymal-Stroma____fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH LRP1 LAMA4 ADAMTS5 VEGFD	4.64e-05	192	91	5	d2c03490c5e835d0f0a732803093c64b8d4b4029
ToppCell	droplet-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH SFRP1 PAMR1 LAMA4 TWSG1	4.64e-05	192	91	5	1b228f0929b505de82a39bf64c837887b0e56701
ToppCell	droplet-Lung-3m-Mesenchymal\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH LRP1 LAMA4 TWSG1 VEGFD	4.64e-05	192	91	5	086b47f87283cd41139cd56686011f8b5821b0da
ToppCell	facs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SFRP1 LRP1 LAMA4 TWSG1 ADAMTS5	4.64e-05	192	91	5	840a34c1b82d218be999ab5e1bcafd6370d7a4b1
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell\|Adult / Lineage, Cell type, age group and donor	CFH DOK6 PAMR1 LAMA4 ADAMTS5	4.64e-05	192	91	5	d21f0f577156f17c899b08871046a26b88aea011
ToppCell	facs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH PAMR1 LRP1 LAMA4 ADAMTS5	4.64e-05	192	91	5	cf2765d8bc074f7f9ee864eae632a3b705175842
ToppCell	Mesenchymal-matrix_fibroblast_2_cell\|World / Lineage, Cell type, age group and donor	CFH DOK6 PAMR1 NTRK3 LAMA4	4.64e-05	192	91	5	a769158c49d2b208c4224d85e7ae68c85cc372ed
ToppCell	facs-Aorta-Heart-3m-Mesenchymal\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CNMD TWSG1 LARS2 PTGFR SORL1	4.64e-05	192	91	5	0dc1f46e40346ed0b286e53b106a812441575100
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH SFRP1 CNMD LRP1 ADAMTS5	4.64e-05	192	91	5	136af0186c70c14c5f2b33ed7a148156de5b478c
ToppCell	facs-Heart-RV-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH SFRP1 LRP1 TWSG1 ADAMTS5	4.76e-05	193	91	5	735a72fac16397edde95e8eefa6f83caeb5ee5df
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	CFH DOK6 LAMA4 VEGFD GAB1	4.76e-05	193	91	5	9f69edc97b868d23998abc98928a2e89a885ef8a
ToppCell	droplet-Lung-30m-Mesenchymal-fibroblast-adventitial_fibroblast\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SFRP1 PAMR1 LAMA4 ADAMTS5 VEGFD	4.76e-05	193	91	5	9d0b966d13cbce97beb43de6dc77f006c363a181
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFH LRP1 LAMA4 TWSG1 VEGFD	4.76e-05	193	91	5	4c74a3f69b2cbdf139e7e66b44bd86869ac34dc0
ToppCell	facs-Lung-EPCAM-3m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH LAMA4 ANO5 TWSG1 VEGFD	4.76e-05	193	91	5	027e098ad018e782287f84eee0f77551018f2196
ToppCell	facs-MAT-Fat-3m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH LRP1 LAMA4 TWSG1 ADAMTS5	4.76e-05	193	91	5	f95b95c58a6edb8a03dd15ae166f47f9f33d8bd6
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFH LRP1 LAMA4 TWSG1 VEGFD	4.76e-05	193	91	5	ff8ceeb3cfd1bef7239df490c19d181091750833
ToppCell	facs-Lung-EPCAM-3m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH LAMA4 ANO5 TWSG1 VEGFD	4.76e-05	193	91	5	c5463a87f20b3a7f7ffda677b2f5a0e9e49d6685
Disease	cystitis (is_marker_for)	MUC2 MUC5AC	8.20e-06	2	85	2	DOID:1679 (is_marker_for)
Disease	sputum mucin-5B amount	MUC2 MUC5AC	2.46e-05	3	85	2	OBA_2050332
Disease	delta and Notch-like epidermal growth factor-related receptor measurement	CFH TRIP12	2.46e-05	3	85	2	EFO_0802458
Disease	Sensorineural Hearing Loss (disorder)	DMXL2 TMC1 LRP2	3.92e-05	23	85	3	C0018784
Disease	endoglin measurement	CFH PLAUR	4.90e-05	4	85	2	EFO_0008118
Disease	mucinous adenocarcinoma (is_marker_for)	MUC2 MUC5AC	8.15e-05	5	85	2	DOID:3030 (is_marker_for)
Disease	Autism Spectrum Disorders	EPHX2 PTCHD1 TRIP12 ITGB3	1.09e-04	85	85	4	C1510586
Disease	Autistic Disorder	FBXO40 PTCHD1 ADSL RNF8 PLAUR ITGB3	1.10e-04	261	85	6	C0004352
Disease	secreted frizzled-related protein 1 measurement	CFH SFRP1	1.22e-04	6	85	2	EFO_0020718
Disease	glutathione s-transferase p measurement	CFH NDUFV1	1.71e-04	7	85	2	EFO_0020410
Disease	bringing up phlegm, sputum or mucus on most days, self-reported	MUC2 MUC5AC	2.91e-04	9	85	2	EFO_0009824
Disease	Headache, glucose measurement	IGF1R GATAD2A	2.91e-04	9	85	2	EFO_0004468, HP_0002315
Disease	membranous glomerulonephritis (biomarker_via_orthology)	CFH LRP2	7.30e-04	14	85	2	DOID:10976 (biomarker_via_orthology)
Disease	pancreatic ductal carcinoma (is_marker_for)	IGF1R NTRK3 MUC5AC	7.36e-04	61	85	3	DOID:3587 (is_marker_for)
Disease	waist-hip ratio	CFH DMXL2 THADA IGF1R MEGF8 MYCBP2 PRIM1 LAMA4 TRIP12 ITGB3 CFAP65	7.77e-04	1226	85	11	EFO_0004343
Disease	Graves' disease (is_marker_for)	IGF1R ITGB3	8.40e-04	15	85	2	DOID:12361 (is_marker_for)
Disease	Colorectal Carcinoma	UNC13B SFRP1 LRP1 LRP2 LAMB3 FBXO30 NLRP8 SORL1	9.49e-04	702	85	8	C0009402
Disease	Schizophrenia	EPHX2 NTRK3 LRP1 LRP2 LARS2 ITGB3 PDE7B NDUFV1 CFAP65	9.98e-04	883	85	9	C0036341
Disease	alcoholic liver cirrhosis	GATAD2A PDE7B	1.08e-03	17	85	2	EFO_1000802
Disease	glaucoma (is_marker_for)	CFH MUC5AC	1.51e-03	20	85	2	DOID:1686 (is_marker_for)
Disease	exploratory eye movement measurement	DMRT1 NLRP8 NLRP13	1.67e-03	81	85	3	EFO_0007700
Disease	nephrosis (biomarker_via_orthology)	CFH LRP2	1.82e-03	22	85	2	DOID:2527 (biomarker_via_orthology)
Disease	blood urea nitrogen measurement	IGF1R PDE7A LRP2 ZRANB1 GAB1 SORL1	1.97e-03	452	85	6	EFO_0004741
Disease	Immunologic Deficiency Syndromes	CFH NBAS	1.99e-03	23	85	2	C0021051
Disease	response to peginterferon alfa-2a	NBAS DMRT1	2.36e-03	25	85	2	EFO_0010103
Disease	diabetes mellitus (implicated_via_orthology)	IGF1R LRP1	2.55e-03	26	85	2	DOID:9351 (implicated_via_orthology)
Disease	myeloperoxidase measurement	CFH THADA	2.55e-03	26	85	2	EFO_0005243
Disease	colorectal health	PAMR1 NTRK3 ADAMTS5 MDFIC2	2.75e-03	201	85	4	EFO_0008460

Protein segments in the cluster

Peptide	Gene	Start	Entry
CKECMLCLGALWDEC	TWSG1	56	Q9GZX9
IMCPLCDQVCDYWRL	ANO5	351	Q75V66
SVCPGMDVCARLWCA	ADAMTS5	506	Q9UNA0
KFSPEVWDETCNCML	ARFGEF2	1461	Q9Y6D5
DCKCPDIWLGCIMED	ADAM11	391	O75078
MLWAICVAEDCNELP	CFH	11	P08603
FWKCCMEANPECNKS	DMXL2	1026	Q8TDJ6
PNCWQLCDRSMIEIE	ADCY10	191	Q96PN6
NCCMSLWVKQNNRCP	RNF7	86	Q9UBF6
MGQRNCDCSVRQCKW	LRRC9	591	Q6ZRR7
IMCPQCDRLCPFWKL	ANO6	346	Q4KMQ2
MCAQCKTDFTCRWRE	GATAD2A	416	Q86YP4
MDVSLCPAKCSFWRI	NTRK3	1	Q16288
SMCRVPVVCWMVCSG	NLRP8	391	Q86W28
SKVCVRSRCWDACMV	NADK2	396	Q4G0N4
EEEMNKWVRCICDIC	GAB1	101	Q13480
EVTNPCDRKKCEWLC	LRP1	4146	Q07954
EEDCTMCPSWCLTVR	CFAP65	746	Q6ZU64
PSWLKSLMTICCCVT	DOP1B	791	Q9Y3R5
WTTNRCQKMCPSTCG	IGF1R	206	P08069
CVSCICWSPFLVTMA	PTGFR	256	P43088
DYKIRVNCCWPMDKC	MUC2	1381	Q02817
MALKCADICNPCRTW	PDE7A	356	Q13946
CADICNPCRIWEMSK	PDE7B	321	Q9NP56
CEQCTREGKCMWTRQ	MEGF8	2001	Q7Z7M0
MAESPGCCSVWARCL	GDPD2	1	Q9HCC8
CPRERMQTSKCDCIW	GDPD2	26	Q9HCC8
RCIPQAWKCDVDNDC	LRP2	3646	P98164
RCIPKWAVCNGVDDC	LRP2	3691	P98164
TCDSRMWRCTDDPCL	MUC5AC	886	P98088
MWRCTDDPCLATCAV	MUC5AC	891	P98088
WCEELACRMVVEPNL	NBAS	801	A2RRP1
DMRWDLEACKSNCSP	FAM170B	161	A6NMN3
CCSSADICPKCWTLM	PRIM1	121	P49642
SQWIPLMEENCRKCS	EPHX2	61	P34913
EEWCKHLCMECLGTR	DOK6	101	Q6PKX4
CAGRCITMKNCARAW	LINC00473	76	A8K010
PLWVCQSCRKSMEED	FAM193B	126	Q96PV7
VCFEQCCPWTFMVKL	IGFL1	76	Q6UW32
CCPWTFMVKLINQNC	IGFL1	81	Q6UW32
GTWEEAMCPLCKRTR	C16orf90	161	A8MZG2
CKERDLWECPSNKQC	CORIN	616	Q9Y5Q5
MQDCWNCCKDLIFDL	DRC7	351	Q8IY82
QVCPASVVCCSMEWN	FBXO40	86	Q9UH90
QCLAVSPMCAWCSDE	ITGB3	41	P05106
EWQMKCCKCDSRQPH	LAMB3	61	Q13751
EMCPASVVCCTMEWN	FBXO30	81	Q8TB52
NCPDELFAVMACCWA	RYK	566	P34925
CSDAVWGMRKACAEC	PPP4R1L	211	Q9P1A2
MWRDCQCKKCNLIAE	DMRT1	96	Q9Y5R6
CQFWDCLLMLPGTCE	MDFIC2	116	A0A1B0GVS7
MGIIDKWTCCSKEVC	OTOGL	1921	Q3ZCN5
EACPGAEWNIMCREC	PAMR1	31	Q6UXH9
CWICKMCRDESKRPP	RGS13	6	O14921
MDCPTISCDKCVWDL	LAMA4	266	Q16363
CWTCLRMTNRCFKGE	IZUMO3	146	Q5VZ72
CLRKWLYIQDTCPMC	RNF139	571	Q8WU17
TVCVFWLMCMCRLNP	RTP5	551	Q14D33
DLIQDFLWMDCCCKI	SPDYA	81	Q5MJ70
VCISLIWKCDGMDDC	SORL1	1336	Q92673
TCDVTAQMVLVCCWR	THADA	1041	Q6YHU6
CINEWMKRKIECPIC	RNF8	426	O76064
AMASEWVNCSCPRCK	LARS2	496	Q15031
VDQWLAMSKKCPICR	RNF165	321	Q6ZSG1
CCSMQDCVRSKPWLG	PTCHD1	286	Q96NR3
QCTPCREGVDWMNKV	NDUFV1	381	P49821
RCCLWIQDLCMDLQN	ADSL	171	P30566
LCMCPLFSCQWEGRL	SIAH3	106	Q8IW03
WKLEQCMVCTVCGDC	MYCBP2	761	O75592
CLDLAASWMKCPLDR	ORC6	51	Q9Y5N6
KIMTCVRPNHTCCWT	WFDC9	56	Q8NEX5
WLCEAVRDSCEPVMQ	SFRP1	131	Q8N474
FQCWAVMCCNVPEAR	TMC1	611	Q8TDI8
CAICWDSMQAARKLP	AMFR	341	Q9UKV5
QGCRSACRVIMPCSW	CNMD	311	O75829
CAACAMLNEPWAVLC	RNF31	306	Q96EP0
MLNEPWAVLCVACDR	RNF31	311	Q96EP0
SPRGKWQCRICEDMF	ZNF451	601	Q9Y4E5
EECMTLWFNREKTCP	RNFT1	396	Q5M7Z0
CVPASWGLRCMQCKT	PLAUR	16	Q03405
WGLRCMQCKTNGDCR	PLAUR	21	Q03405
VKWLEVRCVCPMCNK	RNF122	121	Q9H9V4
CNSRCKCSETKWEPM	SLCO1C1	476	Q9NYB5
CTDVKTQMRCRAPAW	TANGO6	286	Q9C0B7
CPWCNAMNFPRNKVC	TEX13C	961	A0A0J9YWL9
SCACWCPLGRKIHMD	UNC13B	1541	O14795
CDWPRKMSLSCHVCR	TTTY12	71	Q9BZ98
DSLMEEKLECSLWCC	UBE2Q2L	41	H0YL09
SCPERCAAVCGWRQM	TNFRSF25	186	Q93038
KTQCRCQPGMFCAAW	LTBR	121	P36941
PLNWRSKLCTCQDCM	UBR7	306	Q8N806
WVPDKECRRCMQCDA	ZFYVE21	41	Q9BQ24
LCPIDMLWDSNKCKC	VEGFD	221	O43915
ADTWDAKTLMECCRP	TRIP12	1871	Q14669
ENWPSAIKCTMCRAQ	ZRANB1	16	Q9UGI0
LWNLCPDNMEACKSE	THOC1	441	Q96FV9
MCLVRDISNCWAPKV	WDR43	371	Q15061
HMLGKCPNRDCWSTC	ZC3HAV1L	111	Q96H79
MVCWTVCSCLKQPKV	NLRP13	426	Q86W25