Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	phospholipid binding	APBA1 NCF4 ARAP3 MAP1B ANXA1 ANXA4 SPTBN1	1.54e-04	548	43	7	GO:0005543
GeneOntologyMolecularFunction	phospholipase inhibitor activity	ANXA1 ANXA4	3.48e-04	13	43	2	GO:0004859
GeneOntologyBiologicalProcess	supramolecular fiber organization	ESPN SHH AP1AR CAMSAP1 MAP1B SPAG6 TNXB GFAP MYO19 SPTBN1	1.67e-05	957	42	10	GO:0097435
GeneOntologyBiologicalProcess	specification of axis polarity	SHH BCOR	4.03e-05	5	42	2	GO:0065001
GeneOntologyBiologicalProcess	ventricular system development	CELSR2 SPAG6 NME5	6.30e-05	38	42	3	GO:0021591
MousePheno	abnormal brain development	PIGN SHH CAMSAP1 BCOR MAP1B SPAG6 GFAP SPTBN1 NME5	1.17e-05	638	33	9	MP:0000913
Domain	-	ECHDC2 AUH	3.10e-05	4	43	2	1.10.12.10
Domain	Crontonase_C	ECHDC2 AUH	5.15e-05	5	43	2	IPR014748
Domain	Laminin_G_2	FAT4 NELL2 CELSR2	1.06e-04	40	43	3	PF02210
Domain	LamG	FAT4 NELL2 CELSR2	1.41e-04	44	43	3	SM00282
Domain	Enoyl-CoA_hyd/isom_CS	ECHDC2 AUH	1.44e-04	8	43	2	IPR018376
Domain	ENOYL_COA_HYDRATASE	ECHDC2 AUH	2.30e-04	10	43	2	PS00166
Domain	Laminin_G	FAT4 NELL2 CELSR2	3.21e-04	58	43	3	IPR001791
Domain	ANX	ANXA1 ANXA4	3.97e-04	13	43	2	SM00335
Domain	ANNEXIN	ANXA1 ANXA4	3.97e-04	13	43	2	PS00223
Domain	Annexin_repeat_CS	ANXA1 ANXA4	3.97e-04	13	43	2	IPR018252
Domain	Annexin	ANXA1 ANXA4	3.97e-04	13	43	2	PF00191
Domain	Annexin_repeat	ANXA1 ANXA4	3.97e-04	13	43	2	IPR018502
Domain	-	ANXA1 ANXA4	3.97e-04	13	43	2	1.10.220.10
Domain	Growth_fac_rcpt_	FAT4 NELL2 CELSR2 TNXB	4.49e-04	156	43	4	IPR009030
Domain	Annexin	ANXA1 ANXA4	4.63e-04	14	43	2	IPR001464
Domain	Crotonase_core_superfam	ECHDC2 AUH	6.89e-04	17	43	2	IPR001753
Domain	ECH_1	ECHDC2 AUH	6.89e-04	17	43	2	PF00378
Domain	-	ECHDC2 AUH	1.06e-03	21	43	2	3.90.226.10
Domain	ClpP/crotonase-like_dom	ECHDC2 AUH	1.06e-03	21	43	2	IPR029045
Domain	-	FAT4 NELL2 CELSR2	1.36e-03	95	43	3	2.60.120.200
Domain	ASX_HYDROXYL	FAT4 NELL2 CELSR2	1.57e-03	100	43	3	PS00010
Domain	EGF-type_Asp/Asn_hydroxyl_site	FAT4 NELL2 CELSR2	1.86e-03	106	43	3	IPR000152
Domain	hEGF	FAT4 CELSR2	1.88e-03	28	43	2	PF12661
Domain	EGF_3	FAT4 NELL2 CELSR2 TNXB	2.05e-03	235	43	4	PS50026
Domain	EGF	FAT4 NELL2 CELSR2 TNXB	2.05e-03	235	43	4	SM00181
Domain	EGF-like_dom	FAT4 NELL2 CELSR2 TNXB	2.53e-03	249	43	4	IPR000742
Domain	EGF_1	FAT4 NELL2 CELSR2 TNXB	2.76e-03	255	43	4	PS00022
Domain	EGF_CA	FAT4 NELL2 CELSR2	2.77e-03	122	43	3	SM00179
Domain	EGF-like_Ca-bd_dom	FAT4 NELL2 CELSR2	2.90e-03	124	43	3	IPR001881
Domain	EGF-like_CS	FAT4 NELL2 CELSR2 TNXB	3.00e-03	261	43	4	IPR013032
Domain	EGF_2	FAT4 NELL2 CELSR2 TNXB	3.17e-03	265	43	4	PS01186
Domain	LAM_G_DOMAIN	FAT4 CELSR2	3.45e-03	38	43	2	PS50025
Domain	EGF_extracell	NELL2 TNXB	8.42e-03	60	43	2	IPR013111
Pubmed	Autonomous and non-autonomous Shh signalling mediate the in vivo growth and guidance of mouse retinal ganglion cell axons.	SHH FUT4 GFAP	1.47e-07	9	43	3	18832395
Pubmed	Anxa4 mediated airway progenitor cell migration promotes distal epithelial cell fate specification.	SHH ANXA1 ANXA4	2.10e-07	10	43	3	30254199
Pubmed	The role of annexins I, II and IV in tumor development, progression and metastasis of human penile squamous cell carcinomas.	ANXA1 ANXA4	1.49e-06	2	43	2	20602103
Pubmed	ANXA4 Activates JAK-STAT3 Signaling by Interacting with ANXA1 in Basal-Like Breast Cancer.	ANXA1 ANXA4	1.49e-06	2	43	2	32552056
Pubmed	Transient expression of Dp140, a product of the Duchenne muscular dystrophy locus, during kidney tubulogenesis.	FUT4 GFAP	1.49e-06	2	43	2	9013927
Pubmed	The annexins: specific markers of midline structures and sensory neurons in the developing murine central nervous system.	ANXA1 ANXA4	8.94e-06	4	43	2	7706559
Pubmed	Cerebral hypoplasia and craniofacial defects in mice lacking heparan sulfate Ndst1 gene function.	SHH GFAP	8.94e-06	4	43	2	16020517
Pubmed	Suppression of MIP-2 or IL-8 production by annexins A1 and A4 during coculturing of macrophages with late apoptotic human peripheral blood neutrophils.	ANXA1 ANXA4	8.94e-06	4	43	2	22056994
Pubmed	Insm1 promotes differentiation of retinal progenitor cells toward photoreceptor cells in the developing retina through up-regulation of SHH.	SHH GFAP	1.49e-05	5	43	2	36260151
Pubmed	Heterogeneity and timing of translocation and membrane-mediated assembly of different annexins.	ANXA1 ANXA4	1.49e-05	5	43	2	18164291
Pubmed	XLMR candidate mouse gene, Zcchc12 (Sizn1) is a novel marker of Cajal-Retzius cells.	SHH GFAP	2.23e-05	6	43	2	21172456
Pubmed	A role for Sonic hedgehog in axon-to-astrocyte signalling in the rodent optic nerve.	SHH GFAP	2.23e-05	6	43	2	10357934
Pubmed	Characterization of Ca2(+)-dependent phospholipid binding, vesicle aggregation and membrane fusion by annexins.	ANXA1 ANXA4	2.23e-05	6	43	2	2138016
Pubmed	Sonic hedgehog regulates the growth and patterning of the cerebellum.	SHH GFAP	3.12e-05	7	43	2	10375501
Pubmed	Identification and characterization of the acidic pH binding sites for growth regulatory ligands of low density lipoprotein receptor-related protein-1.	ANXA1 ANXA4	3.12e-05	7	43	2	15226301
Pubmed	Transforming Growth Factor-Beta and Sonic Hedgehog Signaling in Palatal Epithelium Regulate Tenascin-C Expression in Palatal Mesenchyme During Soft Palate Development.	SHH TNXB	3.12e-05	7	43	2	32581832
Pubmed	Megalin mediates the influence of sonic hedgehog on oligodendrocyte precursor cell migration and proliferation during development.	SHH GFAP	3.12e-05	7	43	2	22354480
Pubmed	Chloride Accumulators NKCC1 and AE2 in Mouse GnRH Neurons: Implications for GABAA Mediated Excitation.	SLC4A3 GFAP	4.16e-05	8	43	2	26110920
Pubmed	Primary cilia are required for cerebellar development and Shh-dependent expansion of progenitor pool.	SHH GFAP	4.16e-05	8	43	2	18353302
Pubmed	Domains of regulatory gene expression and the developing optic chiasm: correspondence with retinal axon paths and candidate signaling cells.	SHH FUT4	4.16e-05	8	43	2	9886035
Pubmed	Analysis of Ku70 S155 Phospho-Specific BioID2 Interactome Identifies Ku Association with TRIP12 in Response to DNA Damage.	MSH6 MAP1B CDK12 SPTBN1	4.19e-05	156	43	4	37108203
Pubmed	The zinc finger transcriptional repressor Blimp1/Prdm1 is dispensable for early axis formation but is required for specification of primordial germ cells in the mouse.	SHH FUT4	5.35e-05	9	43	2	15750184
Pubmed	Control of oligodendrocyte differentiation by the Nkx2.2 homeodomain transcription factor.	SHH GFAP	5.35e-05	9	43	2	11526078
Pubmed	Hippocampal development and neural stem cell maintenance require Sox2-dependent regulation of Shh.	SHH GFAP	5.35e-05	9	43	2	19734891
Pubmed	Disruption of axo-glial junctions causes cytoskeletal disorganization and degeneration of Purkinje neuron axons.	GFAP SPTBN1	5.35e-05	9	43	2	16551741
Pubmed	Developmental regulation of various annexins in the embryonic palate of the mouse: dexamethasone affects expression of annexin-1.	ANXA1 ANXA4	5.35e-05	9	43	2	8719346
Pubmed	Growth and differentiation factor 10 (Gdf10) is involved in Bergmann glial cell development under Shh regulation.	SHH GFAP	6.68e-05	10	43	2	24963847
Pubmed	Diminished Ventral Oligodendrocyte Precursor Generation Results in the Subsequent Over-production of Dorsal Oligodendrocyte Precursors of Aberrant Morphology and Function.	SHH GFAP	6.68e-05	10	43	2	32450295
Pubmed	SOX2, a persistent marker for multipotential neural stem cells derived from embryonic stem cells, the embryo or the adult.	FUT4 GFAP	6.68e-05	10	43	2	15711057
Pubmed	Akhirin regulates the proliferation and differentiation of neural stem cells in intact and injured mouse spinal cord.	SHH GFAP	9.78e-05	12	43	2	25331329
Pubmed	Altered GLI3 and FGF8 signaling underlies acrocallosal syndrome phenotypes in Kif7 depleted mice.	SHH GFAP	9.78e-05	12	43	2	30445565
Pubmed	Congenital hydrocephalus in genetically engineered mice.	CELSR2 NME5	9.78e-05	12	43	2	21746835
Pubmed	Multifaceted Functions of Rab23 on Primary Cilium-Mediated and Hedgehog Signaling-Mediated Cerebellar Granule Cell Proliferation.	SHH GFAP	1.15e-04	13	43	2	34210780
Pubmed	Control of glial precursor cell development in the mouse optic nerve by sonic hedgehog from retinal ganglion cells.	SHH GFAP	1.15e-04	13	43	2	18625210
Pubmed	Ptch2/Gas1 and Ptch1/Boc differentially regulate Hedgehog signalling in murine primordial germ cell migration.	SHH FUT4	1.15e-04	13	43	2	32332736
Pubmed	High-mobility group nucleosomal binding domain 2 protects against microcephaly by maintaining global chromatin accessibility during corticogenesis.	FUT4 GFAP	1.15e-04	13	43	2	31699896
Pubmed	Different assemblies of Notch receptors coordinate the distribution of the major bronchial Clara, ciliated and neuroendocrine cells.	SHH FUT4	1.15e-04	13	43	2	23132245
Pubmed	Loss of Gli3 and Shh function disrupts olfactory axon trajectories.	SHH GFAP	1.35e-04	14	43	2	15065125
Pubmed	Mesenchymal Vangl1 and Vangl2 facilitate airway elongation and widening independently of the planar cell polarity complex.	SHH CELSR2	1.35e-04	14	43	2	39225402
Pubmed	The Hedgehog pathway promotes blood-brain barrier integrity and CNS immune quiescence.	SHH GFAP	1.35e-04	14	43	2	22144466
Pubmed	Gastrointestinal defects of the Gas1 mutant involve dysregulated Hedgehog and Ret signaling.	SHH GFAP	1.35e-04	14	43	2	23429478
Pubmed	A functional reference map of the RNF8 interactome in cancer.	MAP1B ANXA1 ANXA4 SPTBN1	1.53e-04	218	43	4	35831895
Pubmed	Overexpression of Pax6 results in microphthalmia, retinal dysplasia and defective retinal ganglion cell axon guidance.	SHH GFAP	1.55e-04	15	43	2	18507827
Pubmed	Lack of cadherins Celsr2 and Celsr3 impairs ependymal ciliogenesis, leading to fatal hydrocephalus.	CELSR2 GFAP	1.55e-04	15	43	2	20473291
Pubmed	The foxa2 gene controls the birth and spontaneous degeneration of dopamine neurons in old age.	SHH GFAP	1.55e-04	15	43	2	18076286
Pubmed	Prmt5 promotes ciliated cell specification of airway epithelial progenitors via transcriptional inhibition of Tp63.	SHH FUT4	1.55e-04	15	43	2	37364687
Pubmed	Disrupting hedgehog and WNT signaling interactions promotes cleft lip pathogenesis.	SHH FUT4	1.55e-04	15	43	2	24590292
Pubmed	The ventral hippocampus is the embryonic origin for adult neural stem cells in the dentate gyrus.	SHH GFAP	1.77e-04	16	43	2	23643936
Pubmed	Spatially distinct functions of PAX6 and NKX2.2 during gliogenesis in the ventral spinal cord.	SHH GFAP	1.77e-04	16	43	2	19258013
Pubmed	Motoneurons and oligodendrocytes are sequentially generated from neural stem cells but do not appear to share common lineage-restricted progenitors in vivo.	SHH GFAP	1.77e-04	16	43	2	16407399
Pubmed	MARVELD1 depletion leads to dysfunction of motor and cognition via regulating glia-dependent neuronal migration during brain development.	SHH GFAP	1.77e-04	16	43	2	30250269
Pubmed	Mouse thalamic differentiation: gli-dependent pattern and gli-independent prepattern.	SHH GFAP	1.77e-04	16	43	2	22371696
Pubmed	Suppressor of fused controls mid-hindbrain patterning and cerebellar morphogenesis via GLI3 repressor.	SHH GFAP	2.01e-04	17	43	2	21289193
Pubmed	Persistent Expression of VCAM1 in Radial Glial Cells Is Required for the Embryonic Origin of Postnatal Neural Stem Cells.	FUT4 GFAP	2.26e-04	18	43	2	28728023
Pubmed	The role of Sonic hedgehog of neural origin in thalamic differentiation in the mouse.	SHH GFAP	2.26e-04	18	43	2	19244520
Pubmed	Transcriptomic landscape of early hair follicle and epidermal development.	SHH NUP210	2.26e-04	18	43	2	37318953
Pubmed	Cellular fate decisions in the developing female anteroventral periventricular nucleus are regulated by canonical Notch signaling.	SHH GFAP	2.52e-04	19	43	2	29885287
Pubmed	Coordination of canonical and noncanonical Hedgehog signalling pathways mediated by WDR11 during primordial germ cell development.	SHH FUT4	2.52e-04	19	43	2	37516749
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	KCNS1 LCK FUT4 CDK12 PPP1R27 ARIH2	2.64e-04	730	43	6	34857952
Pubmed	Jagged and Delta-like ligands control distinct events during airway progenitor cell differentiation.	SHH FUT4	3.09e-04	21	43	2	31631837
Pubmed	Otx2 regulates the extent, identity and fate of neuronal progenitor domains in the ventral midbrain.	SHH GFAP	3.40e-04	22	43	2	15105370
Pubmed	Sprouty genes prevent excessive FGF signalling in multiple cell types throughout development of the cerebellum.	SHH GFAP	3.40e-04	22	43	2	21693512
Pubmed	Primary cilia regulate hippocampal neurogenesis by mediating sonic hedgehog signaling.	SHH GFAP	3.72e-04	23	43	2	18728187
Pubmed	A critical role for the protein kinase PKK in the maintenance of recirculating mature B cells and the development of B1 cells.	SHH FUT4	3.72e-04	23	43	2	26921474
Pubmed	Dnmt1 is required for proximal-distal patterning of the lung endoderm and for restraining alveolar type 2 cell fate.	SHH FUT4	3.72e-04	23	43	2	31242446
Pubmed	Cerebellar cortical lamination and foliation require cyclin A2.	SHH GFAP	3.72e-04	23	43	2	24184637
Pubmed	Transposon mutagenesis with coat color genotyping identifies an essential role for Skor2 in sonic hedgehog signaling and cerebellum development.	SHH GFAP	3.72e-04	23	43	2	21937600
Pubmed	Constitutive activation of hedgehog signaling adversely affects epithelial cell fate during palatal fusion.	SHH FUT4	3.72e-04	23	43	2	29981310
Pubmed	Primary cilia in murine palatal rugae development.	SHH CELSR2	3.72e-04	23	43	2	31226309
Pubmed	Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions.	SPHK2 LCK CDK12 ARIH2	3.75e-04	276	43	4	28319085
Pubmed	Proteomic analysis of the cellular responses induced in uninfected immune cells by cell-expressed X4 HIV-1 envelope.	ANXA1 ANXA4	4.05e-04	24	43	2	17676665
Pubmed	DDX3X Suppresses the Susceptibility of Hindbrain Lineages to Medulloblastoma.	SHH GFAP	4.05e-04	24	43	2	32553121
Pubmed	Snf2h-mediated chromatin organization and histone H1 dynamics govern cerebellar morphogenesis and neural maturation.	SHH GFAP	4.05e-04	24	43	2	24946904
Pubmed	Ezh2 represses the basal cell lineage during lung endoderm development.	SHH FUT4	4.05e-04	24	43	2	25516972
Pubmed	Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis.	MSH6 CHPF2 CAMSAP1 CDK12	4.24e-04	285	43	4	32838362
Pubmed	The ciliogenic transcription factor RFX3 regulates early midline distribution of guidepost neurons required for corpus callosum development.	SHH GFAP	4.40e-04	25	43	2	22479201
Pubmed	FGF/FGFR2 signaling regulates the generation and correct positioning of Bergmann glia cells in the developing mouse cerebellum.	SHH GFAP	4.40e-04	25	43	2	24983448
Pubmed	Identification of targets for calcium signaling through the copine family of proteins. Characterization of a coiled-coil copine-binding motif.	BCOR SPTBN1	4.40e-04	25	43	2	12522145
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	APBA1 CELSR2 CAMSAP1 MAP1B ANXA1 GFAP SPTBN1	4.56e-04	1139	43	7	36417873
Pubmed	Deficiency of Wdr60 and Wdr34 cause distinct neural tube malformation phenotypes in early embryos.	SHH CELSR2	4.76e-04	26	43	2	37228654
Pubmed	Activation of PI3K/p110α in the Lung Mesenchyme Affects Branching Morphogenesis and Club Cell Differentiation.	SHH FUT4	5.53e-04	28	43	2	35676931
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	PIGN FAT4 CHPF2 NELL2 CELSR2 MAP1B NUP210	6.25e-04	1201	43	7	35696571
Pubmed	Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.	TNXB ANXA1 ANXA4	6.30e-04	135	43	3	28675934
Pubmed	Gli3 controls corpus callosum formation by positioning midline guideposts during telencephalic patterning.	SHH GFAP	6.35e-04	30	43	2	23042737
Pubmed	Suppressor of fused controls cerebellar neuronal differentiation in a manner modulated by GLI3 repressor and Fgf15.	SHH GFAP	6.35e-04	30	43	2	28560839
Pubmed	Floor plate-derived sonic hedgehog regulates glial and ependymal cell fates in the developing spinal cord.	SHH GFAP	6.35e-04	30	43	2	23482494
Pubmed	Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.	MAP1B CDK12 ANXA1 GFAP SPTBN1	6.38e-04	564	43	5	21565611
Pubmed	SOX1 links the function of neural patterning and Notch signalling in the ventral spinal cord during the neuron-glial fate switch.	SHH GFAP	6.79e-04	31	43	2	19723505
Pubmed	Development and regeneration of Sox2+ endoderm progenitors are regulated by a Hdac1/2-Bmp4/Rb1 regulatory pathway.	SHH FUT4	6.79e-04	31	43	2	23449471
Pubmed	Liver X receptors and oxysterols promote ventral midbrain neurogenesis in vivo and in human embryonic stem cells.	SHH GFAP	6.79e-04	31	43	2	19796621
Pubmed	Expression of early developmental markers predicts the efficiency of embryonic stem cell differentiation into midbrain dopaminergic neurons.	SHH GFAP	6.79e-04	31	43	2	22889265
Pubmed	Visuomotor anomalies in achiasmatic mice expressing a transfer-defective Vax1 mutant.	SHH GFAP	7.23e-04	32	43	2	36737666
Pubmed	Discrete gene sets depend on POU domain transcription factor Brn3b/Brn-3.2/POU4f2 for their expression in the mouse embryonic retina.	SHH NELL2	7.23e-04	32	43	2	14973295
Pubmed	Onset of Spinal Cord Astrocyte Precursor Emigration from the Ventricular Zone Involves the Zeb1 Transcription Factor.	SHH GFAP	7.23e-04	32	43	2	27806288
Pubmed	The role of primary cilia in corpus callosum formation is mediated by production of the Gli3 repressor.	SHH GFAP	7.69e-04	33	43	2	26071364
Pubmed	Derepression of sonic hedgehog signaling upon Gpr161 deletion unravels forebrain and ventricular abnormalities.	SHH GFAP	7.69e-04	33	43	2	30914320
Pubmed	Histone arginine methylation by Prmt5 is required for lung branching morphogenesis through repression of BMP signaling.	SHH FUT4	7.69e-04	33	43	2	29950483
Pubmed	Integration-independent Transgenic Huntington Disease Fragment Mouse Models Reveal Distinct Phenotypes and Life Span in Vivo.	MAP1B GFAP	7.69e-04	33	43	2	26025364
Pubmed	The PRMT5/WDR77 complex regulates alternative splicing through ZNF326 in breast cancer.	CDK12 ANXA1 SPTBN1	8.07e-04	147	43	3	28977470
Pubmed	Microphthalmia/Anophthalmia/Coloboma Spectrum – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY	SHH BCOR	8.17e-04	34	43	2	20301552
GeneFamily	Annexins\|Endogenous ligands	ANXA1 ANXA4	1.92e-04	13	29	2	404
GeneFamily	Ankyrin repeat domain containing	ESPN ARAP3 BCOR PPP1R27	5.72e-04	242	29	4	403
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_T-CytoT_GZMK+-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	KCNS1 LCK MAP1B AUH	1.79e-05	162	43	4	19395bdb282b4a2d88cd33191af12c24a88c3d16
ToppCell	droplet-Liver-LIVER_HEP-30m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	APBA1 CELSR2 SLC4A3 NME5	2.48e-05	176	43	4	5e46a09a36b9645b1b1fcb0b64bd0898561af3a9
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-myocytic-myofibroblast\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DACT3 APBA1 MAP1B SLC4A3	2.77e-05	181	43	4	fc51468c74534b60b4e786bd512d0f1c5dc05de7
ToppCell	3'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Glia_2_(ELN+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NELL2 CELSR2 MAP1B GFAP	2.77e-05	181	43	4	a436e7e4c36403257ea90160a58ca0d6d7c0cdfc
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L3-4_RORB_RPS3P6\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KCNS1 FAT4 SPAG6 ANXA1	3.01e-05	185	43	4	10da5c2a92bfb3248d3f6f94a0933996326cf590
ToppCell	E12.5-Epithelial\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ESPN SHH ANXA1 ANXA4	3.14e-05	187	43	4	29ea5e14dac3321df76f6aa4f053068b49c4a4bf
ToppCell	E12.5-Epithelial-epithelial_progenitor_cell\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ESPN SHH NELL2 ANXA4	3.14e-05	187	43	4	ab6f4d387218b4651fdadbf269806c1ddc96a1d2
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAP1B TNXB ANXA1 SPTBN1	4.00e-05	199	43	4	bfc157be6e9f84739848eb19b718de5b17f3fa88
ToppCell	Hippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6\|Hippocampus / BrainAtlas - Mouse McCarroll V32	ESPN KCNS1 LCK	1.77e-04	113	43	3	6f270b7e59c18243e876311df721e948ce21e850
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Tshz2\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	KCNS1 NELL2 SPAG6	2.16e-04	121	43	3	05c40fd39e6b6275f35aaad835f95a81fcbb0990
ToppCell	VE-CD4-CD8_1\|VE / Condition, Cell_class and T cell subcluster	DACT3 LCK SPAG6	2.27e-04	123	43	3	bc0f509716bb71d6e3fa343f4920ecb80eb62794
ToppCell	facs-Aorta-Heart-3m-Mesenchymal-nan\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SHH KCNS1 NELL2	3.12e-04	137	43	3	587a369b148bb2600c06db39298feddfc99cb6ad
ToppCell	10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_dendritic-plasmacytoid_dendritic_cell\|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	PHKA1 SPAG6 SLC4A3	3.46e-04	142	43	3	7fa6b0f493634d25d68b4365b8c82cd43f5d31db
ToppCell	NS-control-d_0-4-Epithelial-Ciliated-diff\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	SPAG6 ANXA1 NME5	3.46e-04	142	43	3	1e57c75e9f28aae2ca99543448433fa7326398ad
ToppCell	Severe-B_naive-5\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	DACT3 MAP1B ANXA1	4.31e-04	153	43	3	44572f87d403e314050ab935d2cd676c33d9c287
ToppCell	-Hematopoietic_Mast\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANXA1 ANXA4	4.35e-04	32	43	2	ca3d87cac849c1b713acd984626f214f5c8e1433
ToppCell	-Hematopoietic_Mast-Mast_cells-Mast-cells\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANXA1 ANXA4	4.35e-04	32	43	2	c6b707107c661f81e5afa945dd62b37a73bfadf9
ToppCell	-Hematopoietic_Mast-Mast_cells\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANXA1 ANXA4	4.35e-04	32	43	2	de636b6fbdc9368ef6ce7157acbf84e28330cd94
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-lymphocytic-T_lymphocytic-naive_thymus-derived_CD4-positive,_alpha-beta_T_cell\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	NELL2 LCK ANXA1	4.39e-04	154	43	3	561d4d0481e47cf0dc86b09fba2b8f2b128377c9
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c08-GZMK-FOS_h\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	NELL2 SLC4A3 ANXA1	4.39e-04	154	43	3	89c9c9918af32f3952790b41f1471b2c80ffce2f
ToppCell	LPS-IL1RA-Hematopoietic_Meg-Ery-Mes-Epi-like\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SPHK2 BCOR SELENOO	4.64e-04	157	43	3	bd45590da540a557dc8096980a45220fccb99505
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Myeloid\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCF4 TNXB FAM83C	4.64e-04	157	43	3	7fdc0094dd5729990a91a30c1982a14c74650b52
ToppCell	LPS-IL1RA-Hematopoietic_Meg-Ery-Mes-Epi-like-Erythroid\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SPHK2 BCOR SELENOO	4.64e-04	157	43	3	00c9a58b033b8b95b0d838f233dd077b62d8b02a
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Myeloid-microglial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCF4 TNXB FAM83C	4.64e-04	157	43	3	c762b03e254c73222094725ca8ac1c8eb428bccb
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Myeloid-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCF4 TNXB FAM83C	4.64e-04	157	43	3	6b5b08bb5520fcf6f4c0560f7ed7645ec179806d
ToppCell	356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	AP1AR FUT4 TNXB	4.82e-04	159	43	3	1472536eea61d4f13033efe42f128bae1614fa74
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Pld5\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ESPN KCNS1 ECHDC2	4.82e-04	159	43	3	a082e770fa757c4a1d3ed13d53f83297e36faf05
ToppCell	E16.5-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	APBA1 NCF4 GFAP	5.09e-04	162	43	3	9d6931619f5eb847c79d00ff5ae031fef30fd55c
ToppCell	10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8\|blood / Manually curated celltypes from each tissue	KCNS1 NELL2 SPTBN1	5.09e-04	162	43	3	b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_Peritubular_Capilary_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ARAP3 TNXB SPTBN1	5.09e-04	162	43	3	5428c9fdb816f564395ebb4520448e5f3a42b025
ToppCell	10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_dendritic\|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	PHKA1 SPAG6 SLC4A3	5.09e-04	162	43	3	233011408f022647932c81ebab78f9813e3c6833
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c12-FOXP3\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	NELL2 LCK SPAG6	5.18e-04	163	43	3	453e0bb292baca2938d24582fedfd6a8bb1e78e9
ToppCell	droplet-Spleen-nan-3m-Lymphocytic-NK_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARAP3 LCK ANXA1	5.18e-04	163	43	3	2e1c1193c04620cc187b1567dfba025beef1e4e1
ToppCell	Endothelial-B-Donor_01\|World / lung cells shred on cell class, cell subclass, sample id	ARAP3 MAP1B TNXB	5.37e-04	165	43	3	b6893882472aeb0d18e26f47eaec9d53688afcde
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Lymphocytic-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCF4 LCK ANXA1	5.46e-04	166	43	3	b7027802cac6ebf3c4a19ef11c9164d92694a4eb
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Lymphocytic\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCF4 LCK ANXA1	5.46e-04	166	43	3	dbb73742db00982539b1800aef8af2801b3a0598
ToppCell	wk_20-22-Hematologic-Myeloid-GMP\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	ENGASE FUT4 PPP1R27	5.46e-04	166	43	3	d96e88e73a40205f32cebd7e54ca1ff09ee1e7e8
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPAG6 SLC4A3 GFAP	5.56e-04	167	43	3	cf6206c506715cd846799c62cf7c06e3fa99f7af
ToppCell	Int-URO-Lymphocyte-T_NK-CD4_TEM\|Int-URO / Disease, Lineage and Cell Type	NELL2 LCK ECHDC2	5.75e-04	169	43	3	5b2fb89cbc9b92d609994d6e5aa35a67c3cc8f22
ToppCell	TCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-6\|TCGA-Liver / Sample_Type by Project: Shred V9	DACT3 MAP1B TNXB	5.75e-04	169	43	3	e992530776cab922d0360b275fb9cb8bd0017b06
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPAG6 SLC4A3 GFAP	5.75e-04	169	43	3	30141f76e9bfc2b4586429857c72dbc85ba65cc9
ToppCell	control-Epithelial-Ciliated-diff\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	SPAG6 ANXA1 NME5	5.85e-04	170	43	3	334c4103eb6e021766f5638a4ab14b59ad085ac7
ToppCell	TCGA-Cervix\|World / Sample_Type by Project: Shred V9	KCNS1 FAM83C MYO19	5.85e-04	170	43	3	a6cbe253bc60f5d5cb361c7e85ed9928a3155ec8
ToppCell	control-dn_T\|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	LCK ECHDC2 SPTBN1	5.85e-04	170	43	3	839f62860b4a52d06e6a8fce7632195c7310b89d
ToppCell	wk_15-18-Hematologic-Myeloid-GMP\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	FUT4 PPP1R27 NUP210	5.95e-04	171	43	3	4b8b67c289898ae114a07a2147b5a6f8ec9dd308
ToppCell	Endothelial-B-Donor_08\|World / lung cells shred on cell class, cell subclass, sample id	ARAP3 MAP1B TNXB	5.95e-04	171	43	3	07ff7059071da83da1d8f266a586573920d75b58
ToppCell	E12.5-Epithelial-alveolar_epithelial_cell-type_II_pneumocyte\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ESPN SHH ANXA4	5.95e-04	171	43	3	a4d6b0f57eead11b01153688b06b2a45a3b488f2
ToppCell	Endothelial-B-Donor_06\|World / lung cells shred on cell class, cell subclass, sample id	ARAP3 MAP1B TNXB	6.06e-04	172	43	3	8a527dff06d841a86c7eb04a1dd9630787294da4
ToppCell	ASK440-Epithelial-Transformed_epithelium\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	PIGN CELSR2 SELENOO	6.06e-04	172	43	3	df3800bcd9777d02900eba0cfc26ab73de8a1d95
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NELL2 TNXB GFAP	6.16e-04	173	43	3	ee7d1429f23f1b89a9a9f7bc07a84a44cf7acd1c
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NELL2 TNXB GFAP	6.16e-04	173	43	3	3725525b99a6011eda2ff5459b4fd2e1eab1f090
ToppCell	356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	AP1AR FUT4 TNXB	6.16e-04	173	43	3	7e2149205e119cec4f5099c83c85d1e13470137a
ToppCell	wk_15-18-Mesenchymal-Chondrocyte-intermediate_chondrocyte\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	GAL3ST3 KCNS1 GFAP	6.37e-04	175	43	3	a84965d28438a4228d841b357c2cd75cf4b59a63
ToppCell	10x_5'_v1-Neoplastic-Differentiated-like-MES-like\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MAP1B SLC4A3 GFAP	6.37e-04	175	43	3	2dcb5145835c3872d0f92f3ece23730cf65487bd
ToppCell	10x_5'_v1-Neoplastic\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MAP1B SLC4A3 GFAP	6.37e-04	175	43	3	379f595be2273f662064c920d195a30491aa88d6
ToppCell	metastatic_Brain-T/NK_cells-Exhausted_Tfh\|metastatic_Brain / Location, Cell class and cell subclass	NELL2 LCK AUH	6.37e-04	175	43	3	b732c6a423c28856211002107d8c611dcfb6f265
ToppCell	10x_5'_v1-Neoplastic-Differentiated-like\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MAP1B SLC4A3 GFAP	6.37e-04	175	43	3	3c3cbaeec6ef2f61e6b177c95b999752c2d83ddb
ToppCell	TCGA-Thymus-Primary_Tumor-Thymoma-Type_AB\|TCGA-Thymus / Sample_Type by Project: Shred V9	DACT3 GAL3ST3 KCNS1	6.37e-04	175	43	3	50f9b994bdd389158f92f891944ea81b2fb15eef
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Hematopoietic-T_cells-ILCP\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PHKA1 LCK NUP210	6.37e-04	175	43	3	f2c3e0f728a43d6988e793c8a50c964f7447db82
ToppCell	10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MAP1B GFAP SPTBN1	6.37e-04	175	43	3	e99e145a152f534b75267ec492a252a0b814b4f8
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c04-ANXA2\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	ESPN ANXA1 SPTBN1	6.37e-04	175	43	3	5f5fc1bf29f07e086951d4f9486b5f07bdcc5d4f
ToppCell	droplet-Marrow-nan-21m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCF4 ANXA1 SELENOO	6.47e-04	176	43	3	f7d8eb90489a6d22240179abeb0aa16ac24615d3
ToppCell	P03-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SHH ANXA1 ANXA4	6.47e-04	176	43	3	f3a54038cde58326f1caed96ecca33c141bcc8b3
ToppCell	5'-Adult-LymphNode-Hematopoietic-Myeloid-Mast_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	APBA1 PHKA1 ANXA1	6.47e-04	176	43	3	0d203682c372411ba64e97a8eae6c4788e8b6ecf
ToppCell	facs-Skin-nan-18m-Lymphocytic-T_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCF4 ARAP3 LCK	6.58e-04	177	43	3	17065d37fd41f04f67282bee00365daa185e8355
ToppCell	3'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Differentiating_glia\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NELL2 CELSR2 GFAP	6.58e-04	177	43	3	0417460bdb012bc43d7254377fa53d79cdab3f34
ToppCell	facs-Skin-nan-18m-Lymphocytic-nan\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCF4 ARAP3 LCK	6.58e-04	177	43	3	6e45e1a5a894ca2e4ebc5cdb17fdf79e9e188185
ToppCell	facs-Skin-nan-18m-Lymphocytic\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCF4 ARAP3 LCK	6.58e-04	177	43	3	9ff3a77c5c62c8a950c46ca22cd7bde425b84c9a
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NELL2 SPAG6 ANXA1	6.69e-04	178	43	3	731e1e8eff2c4018c75dfc66632a316010a09a9a
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	NELL2 LCK SPTBN1	6.69e-04	178	43	3	31c847d7f7aa0f6d820afbb45d507992f5e9dc2f
ToppCell	droplet-Liver-LIVER_NPC-30m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARAP3 MAP1B TNXB	6.80e-04	179	43	3	025d414ec88d5680d99c8173e70ee3bb0b694f74
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Lymphocytic-T_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCF4 LCK ANXA1	6.80e-04	179	43	3	30efe1f0394c0edb27b91890b5c4637b73cbc5ec
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B-Branch_B2_(eMN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GAL3ST3 NELL2 MAP1B	6.80e-04	179	43	3	d96741c5c551e36421b2ad938072ab7d506c3835
ToppCell	ILEUM-non-inflamed-(7)_Lymphatics\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	NELL2 TNXB SPTBN1	6.80e-04	179	43	3	99777a8931356d1206b8ab22aaa1b1d5a600b809
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c08-GZMK-FOS_h\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	NELL2 LCK ANXA1	6.91e-04	180	43	3	05f14cd367021891166825a8aac171227e2bcd97
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	NELL2 LCK ANXA1	6.91e-04	180	43	3	f3d35b2ea78afef37a84232adf5e6e26712b618d
ToppCell	P03-Epithelial-alveolar_epithelial_cell\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SHH ANXA1 ANXA4	7.02e-04	181	43	3	c3dbf8850d3812fbb770798f4cf38908db8bb92b
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NELL2 SPAG6 ANXA1	7.02e-04	181	43	3	6e8c5460021d3999daec58e3d6661a6fa998fd16
ToppCell	3'-Pediatric_IBD-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DACT3 MAP1B NME5	7.02e-04	181	43	3	ab0f300d14b62cef57f1b0bdae143b8dfe8e6975
ToppCell	wk_15-18-Mesenchymal-Chondrocyte\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	GAL3ST3 KCNS1 GFAP	7.02e-04	181	43	3	8950844b3e65c7028d80da5787ae2ce509c3d52d
ToppCell	3'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-Monocytes\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NCF4 SPAG6 ANXA1	7.02e-04	181	43	3	bad77767e64cc093a827a6b0f3f401f3f108e457
ToppCell	E12.5-Epithelial-epithelial_progenitor_cell-epithelial_progenitor_cell\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ESPN SHH ANXA4	7.13e-04	182	43	3	204530444e35d4977a7239ac176f477e9e5c29ab
ToppCell	Ciliated_cells-B-Donor_04\|World / lung cells shred on cell class, cell subclass, sample id	MAP1B SPAG6 NME5	7.13e-04	182	43	3	e93968f800bfeb258e4e834fc8bf92d1cb72cd73
ToppCell	FLU-Healthy-0\|FLU / Virus stimulation, Condition and Cluster	NELL2 ANXA1 ANXA4	7.25e-04	183	43	3	058604ddb06b3bef131183d86b83b422dae8f6cb
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NELL2 SPAG6 ANXA1	7.25e-04	183	43	3	b5d041d0a3506c33de72bf14fa0443f4410fddf1
ToppCell	5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MAP1B TNXB SPTBN1	7.25e-04	183	43	3	4d16bfbadf2cd13008c35e23dd2b5b4ecf92ee11
ToppCell	E12.5-Epithelial-epithelial_progenitor_cell-epi_progenitor\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ESPN SHH ANXA4	7.25e-04	183	43	3	031b4ffd95114dc10d2932c67d2cfef139b3fd2e
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NELL2 SPAG6 ANXA1	7.25e-04	183	43	3	274076a0978bce2bd53a1732045f18ef0f2d9985
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-myocytic-myofibroblast\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DACT3 FAT4 MAP1B	7.25e-04	183	43	3	af8d86f15a549064530d94bd47081daf59d58ecd
ToppCell	FLU-Healthy-0\|Healthy / Virus stimulation, Condition and Cluster	NELL2 ANXA1 ANXA4	7.25e-04	183	43	3	7a6f18246c39864479e114f698581f667fa9c600
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DACT3 APBA1 MAP1B	7.36e-04	184	43	3	689a8af81a79a4bb3123cfa01958c953eab5de98
ToppCell	E12.5-Epithelial-airway_epithelial_cell-club_cell\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ESPN SHH ANXA1	7.36e-04	184	43	3	a69c3c57cd939b2888f548a0fbca3392ad310445
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KCNS1 NELL2 ANXA1	7.36e-04	184	43	3	6475a43201b136dcc9b113d2ca4cfa154ed9d65d
ToppCell	E12.5-Epithelial-airway_epithelial_cell\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ESPN SHH ANXA1	7.36e-04	184	43	3	3df78b17098b50e1a7f2c8791bf2d0806328330a
ToppCell	droplet-Liver-Hepatocytes-21m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT4 ARAP3 KIF13A	7.48e-04	185	43	3	efcfbf5a48b3ea9a425183e5c2eec6a9585415a0
ToppCell	cellseq-Epithelial-Epithelial_Glandular-MEC-MEC\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MAP1B SLC4A3 GFAP	7.48e-04	185	43	3	76304829fcfb5934188933ca20d33bc8c8b0dc91
ToppCell	ILEUM-inflamed-(7)_Lymphatics\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	NELL2 TNXB SPTBN1	7.48e-04	185	43	3	d711dd2e91cfee723dae1ccb2b910b8cf3becc3b
ToppCell	droplet-Liver-Hepatocytes-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT4 ARAP3 KIF13A	7.48e-04	185	43	3	642088ace9230d38b0579853c54ff4dd8b5d5df4
ToppCell	Ciliated_cells-A-Donor_04\|World / lung cells shred on cell class, cell subclass, sample id	NELL2 MAP1B SPAG6	7.48e-04	185	43	3	d77ca57b02125a3a57a37f4aed20c89803b7d551
ToppCell	cellseq-Epithelial-Epithelial_Glandular-MEC\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MAP1B SLC4A3 GFAP	7.48e-04	185	43	3	0595e7ab37eed690f6e3d16a9a4e9a4bce2b89db
Drug	Aztreonam [78110-38-0]; Down 200; 9.2uM; PC3; HT_HG-U133A	ENGASE AP1AR FUT4 AUH NUP210 ARIH2	1.66e-06	194	43	6	2118_DN
Drug	Tiratricol, 3,3',5-triiodothyroacetic acid [51-24-1]; Down 200; 6.4uM; MCF7; HT_HG-U133A	SPHK2 FUT4 CAMSAP1 MAP1B SPTBN1 NME5	1.82e-06	197	43	6	2259_DN
Drug	Diclofenac sodium [15307-79-6]; Up 200; 12.6uM; PC3; HT_HG-U133A	KCNS1 NCF4 CELSR2 KIF13A SLC4A3 SPTBN1	1.87e-06	198	43	6	5861_UP
Drug	Brompheniramine maleate [980-71-2]; Down 200; 9.2uM; MCF7; HT_HG-U133A	BET1L KCNS1 NCF4 NELL2 CAMSAP1 SPTBN1	1.87e-06	198	43	6	4131_DN
Drug	Cephaeline dihydrochloride heptahydrate [6487-30-5]; Down 200; 6uM; MCF7; HT_HG-U133A	CHPF2 CELSR2 CAMSAP1 MAP1B NUP210	2.20e-05	180	43	5	3290_DN
Drug	Epitiostanol [2363-58-8]; Up 200; 13uM; MCF7; HT_HG-U133A	FAM50B CELSR2 BCOR SPTBN1 NME5	2.93e-05	191	43	5	7342_UP
Drug	17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A	KCNS1 SPHK2 FUT4 CAMSAP1 SLC4A3	3.16e-05	194	43	5	5914_DN
Drug	Mecamylamine hydrochloride [826-39-1]; Up 200; 19.6uM; PC3; HT_HG-U133A	AP1AR KCNS1 MSH6 MAP1B ARIH2	3.32e-05	196	43	5	7263_UP
Drug	Chlorogenic acid [327-97-9]; Down 200; 11.2uM; MCF7; HT_HG-U133A	BET1L KCNS1 NELL2 CAMSAP1 SPTBN1	3.40e-05	197	43	5	4142_DN
Drug	Enalapril maleate [76095-16-4]; Down 200; 8.2uM; MCF7; HT_HG-U133A	CHPF2 SPHK2 CAMSAP1 ECHDC2 NUP210	3.40e-05	197	43	5	7026_DN
Drug	Retinoic acid [302-79-4]; Down 200; 13.4uM; MCF7; HT_HG-U133A	KCNS1 FUT4 KIF13A ANXA1 ARIH2	3.40e-05	197	43	5	3165_DN
Drug	Bumetanide [28395-03-1]; Up 200; 11uM; MCF7; HT_HG-U133A	AP1AR CHPF2 FUT4 SPTBN1 ARIH2	3.40e-05	197	43	5	7440_UP
Drug	Viomycin sulfate [37883-00-4]; Up 200; 5.2uM; PC3; HT_HG-U133A	FAM50B BET1L FAT4 CHPF2 SPTBN1	3.48e-05	198	43	5	7278_UP
Drug	Lidocaone hydrochloride [73-78-9]; Up 200; 14.8uM; MCF7; HT_HG-U133A	ENGASE PIGN KCNS1 KIF13A SPTBN1	3.48e-05	198	43	5	1499_UP
Drug	Hdmnkvldl	MAP1B ANXA1	1.90e-04	11	43	2	CID000159557
Drug	tributyl phosphate	SHH GFAP	1.90e-04	11	43	2	ctd:C009524
Drug	1,1-bis(4-hydroxyphenyl)-2-phenylbut-1-ene	LCK ANXA1	1.90e-04	11	43	2	ctd:C052383
Drug	AC1L9K72	PIGN SPHK2 ANXA1 ANXA4 SPTBN1	2.10e-04	290	43	5	CID000446872
Drug	AC1L4HUP	SPHK2 LCK NUP210	2.20e-04	62	43	3	CID000185960
Drug	methyl vinyl ether	ANXA4 SPTBN1	2.68e-04	13	43	2	CID000007861
Drug	Emetine dihydrochloride [316-42-7]; Down 200; 7.2uM; MCF7; HT_HG-U133A	CHPF2 CELSR2 CAMSAP1 NUP210	3.08e-04	172	43	4	2801_DN
Drug	Etoposide [33419-42-0]; Down 200; 6.8uM; HL60; HG-U133A	PIGN FUT4 SPTBN1 NUP210	3.66e-04	180	43	4	1626_DN
Drug	17-DMAG; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA	ENGASE CHPF2 MAP1B ANXA1	3.98e-04	184	43	4	1051_UP
Drug	Helveticoside [630-64-8]; Down 200; 7.4uM; PC3; HT_HG-U133A	ENGASE SPHK2 SLC4A3 NME5	4.07e-04	185	43	4	4327_DN
Drug	17-AAG; Up 200; 1uM; HL60; HT_HG-U133A	ENGASE CHPF2 ANXA1 ARIH2	4.23e-04	187	43	4	1147_UP
Drug	1pxm	FUT4 SLC4A3 GFAP	4.32e-04	78	43	3	CID000447959
Drug	Cimetidine [51481-61-9]; Up 200; 15.8uM; MCF7; HT_HG-U133A	BET1L KCNS1 GFAP NME5	4.50e-04	190	43	4	4144_UP
Drug	Promazine hydrochloride [53-60-1]; Down 200; 12.4uM; MCF7; HT_HG-U133A	CAMSAP1 KIF13A ARIH2 NME5	4.50e-04	190	43	4	3927_DN
Drug	pyrvinium pamoate; Down 200; 1.25uM; MCF7; HT_HG-U133A_EA	ENGASE MSH6 CHPF2 NUP210	4.50e-04	190	43	4	870_DN
Drug	Ethopropazine hydrochloride [1094-08-2]; Down 200; 11.4uM; MCF7; HT_HG-U133A	FAM50B ENGASE SPTBN1 NUP210	4.50e-04	190	43	4	5296_DN
Drug	Clonidine hydrochloride [4205-91-8]; Down 200; 15uM; MCF7; HT_HG-U133A	KCNS1 FUT4 CAMSAP1 ARIH2	4.50e-04	190	43	4	3172_DN
Drug	Digitoxigenin [143-62-4]; Down 200; 10.6uM; PC3; HT_HG-U133A	FAM50B AP1AR MSH6 FUT4	4.59e-04	191	43	4	4217_DN
Drug	Equilin [474-86-2]; Up 200; 15uM; MCF7; HT_HG-U133A	SPHK2 CELSR2 KIF13A SPAG6	4.68e-04	192	43	4	5620_UP
Drug	Ethoxyquin [91-53-2]; Down 200; 18.4uM; PC3; HT_HG-U133A	BET1L SPHK2 MAP1B NME5	4.77e-04	193	43	4	4321_DN
Drug	Methyl benzethonium chloride [25155-18-4]; Down 200; 8.6uM; MCF7; HT_HG-U133A	FAM50B NCF4 FUT4 ARIH2	4.77e-04	193	43	4	3943_DN
Drug	lactofen	APBA1 MSH6 CELSR2	4.83e-04	81	43	3	CID000062276
Drug	Cefaclor [70356-03-5]; Up 200; 10.4uM; MCF7; HT_HG-U133A	APBA1 NCF4 KIF13A NME5	4.86e-04	194	43	4	4967_UP
Drug	Spiramycin [8025-81-8]; Down 200; 4.8uM; MCF7; HT_HG-U133A	PIGN SPHK2 NELL2 KIF13A	4.86e-04	194	43	4	3938_DN
Drug	Doxazosin mesylate [77883-43-3]; Up 200; 7.4uM; MCF7; HT_HG-U133A	KCNS1 NELL2 FUT4 NME5	4.86e-04	194	43	4	3363_UP
Drug	Meclozine dihydrochloride [1104-22-9]; Up 200; 8.6uM; MCF7; HT_HG-U133A	APBA1 MAP1B KIF13A NME5	4.86e-04	194	43	4	3285_UP
Drug	Omeprazole [73590-58-6]; Up 200; 11.6uM; MCF7; HT_HG-U133A	KCNS1 NCF4 CAMSAP1 NME5	4.86e-04	194	43	4	4951_UP
Drug	Phentolamine hydrochloride [73-05-2]; Down 200; 12.6uM; PC3; HT_HG-U133A	BET1L SPHK2 CELSR2 SPTBN1	4.86e-04	194	43	4	3779_DN
Drug	Scoulerine [6451-73-6]; Down 200; 12.2uM; MCF7; HT_HG-U133A	ENGASE PIGN MAP1B SPTBN1	4.86e-04	194	43	4	2891_DN
Drug	Pergolide mesylate [66104-23-2]; Up 200; 9.8uM; MCF7; HT_HG-U133A	ENGASE CHPF2 FUT4 SPTBN1	4.96e-04	195	43	4	7434_UP
Drug	Prenylamine lactate [69-43-2]; Down 200; 9.6uM; PC3; HT_HG-U133A	SPHK2 SPTBN1 ARIH2 NME5	4.96e-04	195	43	4	5070_DN
Drug	Bupivacaine hydrochloride [18010-40-7]; Up 200; 12.4uM; MCF7; HT_HG-U133A	KCNS1 CHPF2 SPTBN1 NUP210	4.96e-04	195	43	4	7435_UP
Drug	Zomepirac sodium salt [64092-48-4]; Up 200; 12.8uM; MCF7; HT_HG-U133A	PIGN BET1L FUT4 NME5	4.96e-04	195	43	4	3454_UP
Drug	Ethionamide [536-33-4]; Up 200; 24uM; PC3; HT_HG-U133A	KCNS1 SPHK2 NELL2 KIF13A	4.96e-04	195	43	4	4593_UP
Drug	Amphotericin B [1397-89-3]; Up 200; 4.4uM; PC3; HT_HG-U133A	BET1L FUT4 CELSR2 SPTBN1	4.96e-04	195	43	4	6303_UP
Drug	Dextromethorphan hydrobromide monohydrate [6700-34-1]; Up 200; 10.8uM; MCF7; HT_HG-U133A	SPHK2 NCF4 CAMSAP1 SPTBN1	4.96e-04	195	43	4	5401_UP
Drug	Nafcillin sodium salt monohydrate [7177-50-6]; Down 200; 8.8uM; MCF7; HT_HG-U133A	NCF4 CAMSAP1 MAP1B MYO19	4.96e-04	195	43	4	4103_DN
Drug	Alverine citrate salt [5560-59-8]; Down 200; 8.4uM; PC3; HT_HG-U133A	FAM50B AUH SPTBN1 ARIH2	5.05e-04	196	43	4	2110_DN
Drug	(1)-Nipecotic acid [498-95-3]; Down 200; 31uM; HL60; HT_HG-U133A	KCNS1 CELSR2 CAMSAP1 ARIH2	5.05e-04	196	43	4	3121_DN
Drug	Enoxacin [74011-58-8]; Down 200; 12.4uM; HL60; HG-U133A	FAM50B KCNS1 CHPF2 NUP210	5.05e-04	196	43	4	1597_DN
Drug	Nicergoline; Up 200; 8.2uM; PC3; HT_HG-U133A	AP1AR FUT4 AUH NME5	5.05e-04	196	43	4	2058_UP
Drug	Sulfaguanidine [57-67-0]; Up 200; 18.6uM; MCF7; HT_HG-U133A	ENGASE SPHK2 NELL2 SPTBN1	5.05e-04	196	43	4	1495_UP
Drug	Tomatidine [77-59-8]; Up 200; 9.6uM; PC3; HT_HG-U133A	FAM50B KCNS1 CHPF2 ARIH2	5.05e-04	196	43	4	5808_UP
Drug	LY294002; Down 200; 10uM; MCF7; HT_HG-U133A	PIGN SPHK2 BCOR NME5	5.05e-04	196	43	4	5937_DN
Drug	0393-0188; Down 200; 10uM; MCF7; HT_HG-U133A	BET1L SPHK2 NELL2 CAMSAP1	5.05e-04	196	43	4	7531_DN
Drug	Sulfadimethoxine [122-11-2]; Up 200; 12.8uM; MCF7; HT_HG-U133A	KCNS1 KIF13A SPTBN1 NME5	5.05e-04	196	43	4	3441_UP
Drug	Mifepristone [84371-65-3]; Down 200; 9.4uM; HL60; HG-U133A	PIGN CHPF2 CAMSAP1 MYO19	5.05e-04	196	43	4	1569_DN
Drug	fluphenazine dihydrochloride; Down 200; 10uM; HL60; HT_HG-U133A	SPHK2 CELSR2 CAMSAP1 SPAG6	5.05e-04	196	43	4	2697_DN
Drug	Etidronic acid, disodium salt [7414-83-7]; Up 200; 16uM; PC3; HT_HG-U133A	SPHK2 NELL2 CAMSAP1 KIF13A	5.05e-04	196	43	4	4564_UP
Drug	Dehydroisoandosterone 3-acetate [853-23-6]; Down 200; 12.2uM; PC3; HT_HG-U133A	CAMSAP1 BCOR MAP1B NUP210	5.05e-04	196	43	4	6673_DN
Drug	Triprolidine hydrochloride [550-70-9]; Up 200; 12.8uM; MCF7; HT_HG-U133A	CHPF2 FUT4 SPTBN1 ARIH2	5.05e-04	196	43	4	7408_UP
Drug	Ampyrone [83-07-8]; Down 200; 19.6uM; MCF7; HT_HG-U133A	KCNS1 FUT4 CAMSAP1 KIF13A	5.05e-04	196	43	4	2249_DN
Drug	Menadione [58-27-5]; Down 200; 23.2uM; HL60; HT_HG-U133A	MSH6 FUT4 CELSR2 NUP210	5.15e-04	197	43	4	2439_DN
Drug	Sulfabenzamide [127-71-9]; Up 200; 14.4uM; MCF7; HT_HG-U133A	FAM50B NCF4 KIF13A NME5	5.15e-04	197	43	4	4979_UP
Drug	Gelsemine [509-15-9]; Up 200; 12.4uM; MCF7; HT_HG-U133A	KCNS1 SPHK2 KIF13A ARIH2	5.15e-04	197	43	4	2817_UP
Drug	Succinylsulfathiazole [116-43-8]; Down 200; 11.2uM; MCF7; HT_HG-U133A	MSH6 ANXA1 SPTBN1 ARIH2	5.15e-04	197	43	4	4847_DN
Drug	Pirenperone [ 75444-65-4]; Down 200; 10.2uM; PC3; HT_HG-U133A	FUT4 SPTBN1 NUP210 NME5	5.15e-04	197	43	4	4679_DN
Drug	Butylparaben [94-26-8]; Up 200; 20.6uM; MCF7; HT_HG-U133A	BET1L FAT4 CAMSAP1 SPTBN1	5.15e-04	197	43	4	5245_UP
Drug	Trioxsalen [3902-71-4]; Down 200; 17.6uM; MCF7; HT_HG-U133A	SPHK2 CAMSAP1 MAP1B AUH	5.15e-04	197	43	4	6216_DN
Drug	Kanamycin A sulfate [25389-94-0]; Up 200; 6.8uM; HL60; HG-U133A	KCNS1 NELL2 FUT4 CDK12	5.15e-04	197	43	4	1609_UP
Drug	Mafenide hydrochloride [138-37-4]; Down 200; 18uM; PC3; HT_HG-U133A	MSH6 SPTBN1 NUP210 ARIH2	5.15e-04	197	43	4	2124_DN
Drug	Deoxycorticosterone [64-85-7]; Up 200; 12.2uM; MCF7; HT_HG-U133A	ENGASE CHPF2 FUT4 MAP1B	5.15e-04	197	43	4	5357_UP
Drug	STOCK1N-35874; Down 200; 14uM; PC3; HT_HG-U133A	FAT4 SPHK2 SLC4A3 SPTBN1	5.15e-04	197	43	4	6583_DN
Drug	Pramoxine hydrochloride [637-58-1]; Down 200; 12.2uM; MCF7; HT_HG-U133A	ENGASE KCNS1 SPTBN1 NME5	5.15e-04	197	43	4	3894_DN
Drug	clozapine; Up 200; 10uM; MCF7; HT_HG-U133A	SPHK2 CAMSAP1 SPTBN1 ARIH2	5.15e-04	197	43	4	6947_UP
Drug	4-(fluoromethyl)phenyl phosphate	MSH6 SPTBN1	5.23e-04	18	43	2	CID000192584
Drug	AC1L9IU6	FUT4 GFAP	5.23e-04	18	43	2	CID000445952
Drug	Vitexin [3681-93-4]; Up 200; 9.2uM; HL60; HT_HG-U133A	FAT4 SPHK2 CAMSAP1 SPTBN1	5.25e-04	198	43	4	2155_UP
Drug	Bergenin monohydrate [477-90-7]; Up 200; 11.6uM; MCF7; HT_HG-U133A	PIGN BET1L GFAP NME5	5.25e-04	198	43	4	7224_UP
Drug	Dantrolene sodium salt [14663-23-1]; Up 200; 11.8uM; PC3; HT_HG-U133A	NELL2 CAMSAP1 MAP1B SPTBN1	5.25e-04	198	43	4	4343_UP
Drug	Bethanechol chloride [590-63-6]; Down 200; 20.4uM; MCF7; HT_HG-U133A	PIGN SPHK2 MAP1B KIF13A	5.25e-04	198	43	4	3537_DN
Drug	Hydrochlorothiazide [58-93-5]; Up 200; 13.4uM; PC3; HT_HG-U133A	BET1L KCNS1 NELL2 KIF13A	5.25e-04	198	43	4	6625_UP
Drug	Ethambutol dihydrochloride [1070-11-7]; Down 200; 14.4uM; PC3; HG-U133A	PIGN SPHK2 AUH NUP210	5.25e-04	198	43	4	1900_DN
Drug	Diphemanil methylsulfate [62-97-5]; Down 200; 10.2uM; PC3; HG-U133A	SPHK2 CAMSAP1 MYO19 NUP210	5.25e-04	198	43	4	1912_DN
Drug	Guaifenesin [93-14-1]; Down 200; 20.2uM; MCF7; HT_HG-U133A	PIGN FUT4 KIF13A NME5	5.25e-04	198	43	4	3897_DN
Drug	Meclofenoxate hydrochloride [3685-84-5]; Up 200; 13.6uM; MCF7; HT_HG-U133A	FUT4 CAMSAP1 SPTBN1 ARIH2	5.25e-04	198	43	4	3405_UP
Drug	Zoxazolamine [61-80-3]; Down 200; 23.8uM; PC3; HT_HG-U133A	FUT4 MYO19 SPTBN1 NUP210	5.25e-04	198	43	4	6290_DN
Drug	Ketotifen fumarate [34580-14-8]; Down 200; 9.4uM; HL60; HG-U133A	ENGASE PIGN CHPF2 CAMSAP1	5.25e-04	198	43	4	1583_DN
Drug	Zaprinast [37762-06-4]; Up 200; 14.8uM; PC3; HT_HG-U133A	SLC4A3 NUP210 ARIH2 NME5	5.25e-04	198	43	4	6749_UP
Drug	PF-00539758-00 [351321-34-1]; Down 200; 10uM; PC3; HT_HG-U133A	FAM50B NELL2 CELSR2 NUP210	5.25e-04	198	43	4	6421_DN
Drug	Trimethoprim [738-70-5]; Up 200; 13.8uM; MCF7; HT_HG-U133A	KCNS1 CHPF2 CAMSAP1 NME5	5.25e-04	198	43	4	4701_UP
Drug	Proparacaine hydrochloride [5875-06-9]; Down 200; 12uM; MCF7; HT_HG-U133A	PIGN SPHK2 FUT4 SPTBN1	5.25e-04	198	43	4	5433_DN
Drug	Diflunisal [22494-42-4]; Down 200; 16uM; MCF7; HT_HG-U133A	CAMSAP1 KIF13A SPTBN1 NUP210	5.25e-04	198	43	4	4794_DN
Drug	Orphenadrine hydrochloride [341-69-5]; Down 200; 13uM; MCF7; HT_HG-U133A	FAM50B ENGASE KCNS1 NME5	5.25e-04	198	43	4	3883_DN
Drug	Sulfapyridine [144-83-2]; Up 200; 16uM; PC3; HT_HG-U133A	FAM50B ARAP3 NUP210 ARIH2	5.25e-04	198	43	4	7151_UP
Drug	Nadolol [42200-33-9]; Down 200; 13uM; MCF7; HT_HG-U133A	APBA1 KCNS1 NELL2 CAMSAP1	5.25e-04	198	43	4	4139_DN
Disease	hypothyroidism (biomarker_via_orthology)	SHH MAP1B ANXA1	2.19e-04	80	43	3	DOID:1459 (biomarker_via_orthology)
Disease	hydrocephalus (implicated_via_orthology)	CELSR2 NME5	3.49e-04	19	43	2	DOID:10908 (implicated_via_orthology)
Disease	Squamous cell carcinoma of esophagus	FAT4 TNXB ANXA1	3.63e-04	95	43	3	C0279626
Disease	basophil count, eosinophil count	NCF4 AUH TNXB ARIH2	4.17e-04	241	43	4	EFO_0004842, EFO_0005090
Disease	Neoplasm of uncertain or unknown behavior of ovary	MSH6 CDK12	8.21e-04	29	43	2	C0496920
Disease	Ovarian Carcinoma	MSH6 CDK12	8.79e-04	30	43	2	C0029925
Disease	aortic stenosis	BET1L CELSR2	9.39e-04	31	43	2	EFO_0000266
Disease	coronary artery disease	BET1L FAT4 CELSR2 MAP1B CDK12 TNXB NUP210	1.57e-03	1194	43	7	EFO_0001645

Protein segments in the cluster

Peptide	Gene	Start	Entry
EAAYQADDRQDLLSA	SLC4A3	586	P48751
ADFGLARLYNSEESR	CDK12	876	Q9NYV4
RQDLEAREDAGYASL	ARAP3	236	Q8WWN8
DADEGTNADIRYRLQ	FAT4	276	Q6V0I7
DIDRDAEDQNRYLDG	BET1L	41	Q9NYM9
VERADSYDRGDLENQ	ARIH2	461	O95376
EEALYAAQREAARAA	AP1AR	106	Q63HQ0
DADAGDNARLEYRLA	CELSR2	531	Q9HCU4
DEGNYLDDALVRQDA	ANXA4	161	P09525
DYLNDLQGRNDDDAS	BCOR	1581	Q6W2J9
DGAADLVPLDRYDAA	CAMSAP1	21	Q5T5Y3
EDLADSDARALYEAG	ANXA1	196	P04083
RLDLAAYDQEGRRFD	NUP210	786	Q8TEM1
RRLLDDISNGYDDSE	MAP1B	1981	P46821
DGFRALREDNAYCED	NELL2	426	Q99435
GSDGQAREYLREDLQ	MYO19	11	Q96H55
NQEGDAAYRKALDLA	AUH	261	Q13825
RVLDYEEAAAAAEAL	FUT4	266	P22083
GLGLAYRKNADRDED	PHKA1	56	P46020
EGDAAYQRARALAQE	ECHDC2	216	Q86YB7
RDRDGYTAADLSDFN	ESPN	301	B1AK53
DSLRAIYGTDDLRNA	NME5	111	P56597
NYRDAEGDLVRLLSD	NCF4	286	Q15080
ARLIEDNEYTAREGA	LCK	386	P06239
EQARRLCDDYDEAAR	KCNS1	86	Q96KK3
AYRQEADEATLARLD	GFAP	171	P14136
AGFDSDYDQALADIR	MSH6	931	P52701
GDNERSPRDDAAYLA	GAL3ST3	211	Q96A11
DEDAAAARRAAAALE	DACT3	66	Q96B18
RLAADALLERGEAAY	FAM83C	46	Q9BQN1
DGLRLYEQERDEAAA	APBA1	211	Q02410
DEAAAYRQEALGARL	APBA1	221	Q02410
LAGDERSYQAVADRL	ENGASE	206	Q8NFI3
LQRGLDSYQRDDEDG	KIF13A	1066	Q9H1H9
AALALGRLANYNDDL	SPAG6	61	O75602
GDRVLAADDQGRLLY	SHH	221	Q15465
AYRARLDKDLEGAGD	SELENOO	561	Q9BVL4
DAARLQAAYAGDKAD	SPTBN1	1866	Q01082
NADYLAARARLAGEL	CHPF2	676	Q9P2E5
DIARYLISLGADRDA	PPP1R27	111	Q86WC6
RADGAATYEENRAEA	SPHK2	136	Q9NRA0
DLRAGDEAVFAQYDS	TNXB	4121	P22105
ADGLRADALYELDEN	PIGN	51	O95427
ADALYELDENGNSRA	PIGN	56	O95427
DLDDQADAAEARRAG	FAM50B	126	Q9Y247