Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ABC-type transporter activity	ABCG1 ABCA2 ABCD3 ATP13A3 ABCB4	2.04e-06	49	85	5	GO:0140359
GeneOntologyMolecularFunction	calmodulin binding	TRPV1 MYH8 EGFR PSG4 PIK3R1 SPTBN1 SCN3A RYR2	6.16e-06	230	85	8	GO:0005516
GeneOntologyMolecularFunction	ATPase-coupled transmembrane transporter activity	ATP6V1A ABCG1 ABCA2 ABCD3 ATP13A3 ABCB4	7.10e-06	109	85	6	GO:0042626
GeneOntologyMolecularFunction	transmembrane transporter activity	ATP6V1A TRPV1 ABCG1 ABCA2 MPC1L TRPM3 PSG4 SCN3A SCN4A SLC19A2 ABCD3 SLCO3A1 ATP13A3 RYR2 SLC6A14 ABCB4	3.29e-05	1180	85	16	GO:0022857
GeneOntologyMolecularFunction	floppase activity	ABCG1 ABCA2 ABCB4	4.01e-05	16	85	3	GO:0140328
GeneOntologyMolecularFunction	ceramide floppase activity	ABCA2 ABCB4	5.36e-05	3	85	2	GO:0099038
GeneOntologyMolecularFunction	transporter activity	ATP6V1A TRPV1 ABCG1 ABCA2 MPC1L TRPM3 PSG4 SCN3A SCN4A SLC19A2 ABCD3 SLCO3A1 ATP13A3 RYR2 SLC6A14 ABCB4	9.43e-05	1289	85	16	GO:0005215
GeneOntologyMolecularFunction	ribonucleoside triphosphate phosphatase activity	ATP6V1A MYH8 ABCG1 ABCA2 ENTPD3 ABCD3 ATP13A3 KATNA1 RAB14 SNRNP200 AGAP1 ABCB4	1.05e-04	775	85	12	GO:0017111
GeneOntologyMolecularFunction	sphingolipid floppase activity	ABCA2 ABCB4	1.07e-04	4	85	2	GO:0046623
GeneOntologyMolecularFunction	ATP hydrolysis activity	ATP6V1A MYH8 ABCG1 ABCA2 ABCD3 ATP13A3 KATNA1 SNRNP200 ABCB4	1.08e-04	441	85	9	GO:0016887
GeneOntologyMolecularFunction	primary active transmembrane transporter activity	ATP6V1A ABCG1 ABCA2 ABCD3 ATP13A3 ABCB4	1.13e-04	178	85	6	GO:0015399
GeneOntologyMolecularFunction	lipid transporter activity	ABCG1 ABCA2 PSG4 ABCD3 SLCO3A1 ABCB4	1.90e-04	196	85	6	GO:0005319
GeneOntologyMolecularFunction	pyrophosphatase activity	ATP6V1A MYH8 ABCG1 ABCA2 ENTPD3 ABCD3 ATP13A3 KATNA1 RAB14 SNRNP200 AGAP1 ABCB4	2.19e-04	839	85	12	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	ATP6V1A MYH8 ABCG1 ABCA2 ENTPD3 ABCD3 ATP13A3 KATNA1 RAB14 SNRNP200 AGAP1 ABCB4	2.22e-04	840	85	12	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	ATP6V1A MYH8 ABCG1 ABCA2 ENTPD3 ABCD3 ATP13A3 KATNA1 RAB14 SNRNP200 AGAP1 ABCB4	2.22e-04	840	85	12	GO:0016818
GeneOntologyMolecularFunction	ATPase-coupled intramembrane lipid transporter activity	ABCG1 ABCA2 ABCB4	2.26e-04	28	85	3	GO:0140326
GeneOntologyMolecularFunction	ferroxidase activity	FTH1 FTMT	2.66e-04	6	85	2	GO:0004322
GeneOntologyMolecularFunction	oxidoreductase activity, acting on metal ions, oxygen as acceptor	FTH1 FTMT	2.66e-04	6	85	2	GO:0016724
GeneOntologyMolecularFunction	lipid transmembrane transporter activity	ABCG1 PSG4 ABCD3 SLCO3A1	2.66e-04	73	85	4	GO:0170055
GeneOntologyMolecularFunction	ATP-dependent activity	ATP6V1A MYH8 ABCG1 ABCA2 EP400 ABCD3 ATP13A3 KATNA1 SNRNP200 ABCB4	2.76e-04	614	85	10	GO:0140657
GeneOntologyMolecularFunction	dolichyl-phosphate-mannose-protein mannosyltransferase activity	TMTC4 POMT1	4.93e-04	8	85	2	GO:0004169
GeneOntologyMolecularFunction	phosphatidylcholine floppase activity	ABCG1 ABCB4	4.93e-04	8	85	2	GO:0090554
GeneOntologyMolecularFunction	ferric iron binding	FTH1 FTMT	9.61e-04	11	85	2	GO:0008199
GeneOntologyMolecularFunction	active transmembrane transporter activity	ATP6V1A ABCG1 ABCA2 ABCD3 SLCO3A1 ATP13A3 SLC6A14 ABCB4	9.63e-04	477	85	8	GO:0022804
GeneOntologyMolecularFunction	intramembrane lipid transporter activity	ABCG1 ABCA2 ABCB4	1.34e-03	51	85	3	GO:0140303
GeneOntologyMolecularFunction	organic anion transmembrane transporter activity	MPC1L PSG4 SLC19A2 ABCD3 SLCO3A1 SLC6A14	1.57e-03	293	85	6	GO:0008514
GeneOntologyMolecularFunction	carboxylic acid transmembrane transporter activity	MPC1L PSG4 SLC19A2 ABCD3 SLC6A14	1.91e-03	207	85	5	GO:0046943
GeneOntologyMolecularFunction	organic acid transmembrane transporter activity	MPC1L PSG4 SLC19A2 ABCD3 SLC6A14	1.95e-03	208	85	5	GO:0005342
GeneOntologyMolecularFunction	hexosyltransferase activity	TMTC4 GALNT8 EXT1 POMT1 ALG13	2.08e-03	211	85	5	GO:0016758
GeneOntologyMolecularFunction	intracellularly gated calcium channel activity	TRPV1 RYR2	2.62e-03	18	85	2	GO:0015278
GeneOntologyMolecularFunction	oxidoreductase activity, acting on metal ions	FTH1 FTMT	2.62e-03	18	85	2	GO:0016722
GeneOntologyMolecularFunction	phosphatidylcholine transporter activity	ABCG1 ABCB4	3.24e-03	20	85	2	GO:0008525
GeneOntologyMolecularFunction	sphingolipid transporter activity	ABCA2 ABCB4	3.24e-03	20	85	2	GO:0046624
GeneOntologyMolecularFunction	monoatomic cation channel activity	ATP6V1A TRPV1 TRPM3 SCN3A SCN4A RYR2	3.45e-03	343	85	6	GO:0005261
GeneOntologyBiologicalProcess	circulatory system process	TRPV1 ABCA2 ADIPOQ EGFR PSG4 PIK3R1 SCN3A SCN4A SLCO3A1 FGF13 EXT1 RYR2	5.09e-05	733	86	12	GO:0003013
GeneOntologyBiologicalProcess	ceramide translocation	ABCA2 ABCB4	5.14e-05	3	86	2	GO:0099040
GeneOntologyBiologicalProcess	carbohydrate derivative biosynthetic process	ATP6V1A AMPD3 ABCA2 TMTC4 GALNT8 CHST9 EXT1 POMT1 ELOVL6 UST HACD1 ALG13	5.30e-05	736	86	12	GO:1901137
GeneOntologyBiologicalProcess	sulfur compound biosynthetic process	SLC19A2 CHST9 EXT1 ELOVL6 UST HACD1	1.01e-04	178	86	6	GO:0044272
GeneOntologyBiologicalProcess	small molecule biosynthetic process	NLN ABCG1 ABCA2 SPTSSA ADIPOQ PSG4 SLC19A2 ABCD3 ELOVL6 UST HACD1	1.13e-04	676	86	11	GO:0044283
GeneOntologyBiologicalProcess	glycoprotein biosynthetic process	ABCA2 TMTC4 GALNT8 CHST9 EXT1 POMT1 UST ALG13	1.22e-04	357	86	8	GO:0009101
GeneOntologyBiologicalProcess	sphingolipid translocation	ABCA2 ABCB4	1.70e-04	5	86	2	GO:0099039
GeneOntologyBiologicalProcess	actin-mediated cell contraction	MYH8 SCN3A SCN4A FGF13 RYR2	1.91e-04	127	86	5	GO:0070252
GeneOntologyBiologicalProcess	protein catabolic process	FEM1B PSMD6 CUL1 USP8 NLN ABCA2 EGFR PSG4 EXT1 UBE3C ATE1 MMP9 RNF139 HERPUD1	1.98e-04	1115	86	14	GO:0030163
GeneOntologyBiologicalProcess	heart contraction	TRPV1 PIK3R1 SCN3A SCN4A FGF13 EXT1 RYR2	2.48e-04	298	86	7	GO:0060047
GeneOntologyBiologicalProcess	monoatomic cation transport	ATP6V1A TRPV1 TRPM3 SCN3A SCN4A FTH1 FTMT CCR5 FGF13 FGF14 ATP13A3 MMP9 RYR2 SLC6A14	2.90e-04	1157	86	14	GO:0006812
GeneOntologyBiologicalProcess	heart process	TRPV1 PIK3R1 SCN3A SCN4A FGF13 EXT1 RYR2	3.09e-04	309	86	7	GO:0003015
GeneOntologyBiologicalProcess	carboxylic acid transport	TRPV1 MPC1L PSG4 SLC19A2 ABCD3 SLCO3A1 SLC6A14 ABCB4	3.12e-04	410	86	8	GO:0046942
GeneOntologyBiologicalProcess	organic acid transport	TRPV1 MPC1L PSG4 SLC19A2 ABCD3 SLCO3A1 SLC6A14 ABCB4	3.23e-04	412	86	8	GO:0015849
GeneOntologyBiologicalProcess	intracellular sequestering of iron ion	FTH1 FTMT	3.56e-04	7	86	2	GO:0006880
GeneOntologyBiologicalProcess	blood circulation	TRPV1 ADIPOQ EGFR PSG4 PIK3R1 SCN3A SCN4A FGF13 EXT1 RYR2	3.61e-04	648	86	10	GO:0008015
GeneOntologyBiologicalProcess	regulation of cholesterol transport	ABCG1 ABCA2 ADIPOQ ABCB4	4.03e-04	83	86	4	GO:0032374
GeneOntologyBiologicalProcess	regulation of sterol transport	ABCG1 ABCA2 ADIPOQ ABCB4	4.03e-04	83	86	4	GO:0032371
GeneOntologyBiologicalProcess	very long-chain fatty acid metabolic process	ABCD3 ELOVL6 HACD1	4.16e-04	35	86	3	GO:0000038
GeneOntologyBiologicalProcess	glycoprotein metabolic process	ABCA2 TMTC4 GALNT8 CHST9 EXT1 POMT1 UST ALG13	4.29e-04	430	86	8	GO:0009100
GeneOntologyBiologicalProcess	actin filament-based movement	MYH8 SCN3A SCN4A FGF13 RYR2	4.52e-04	153	86	5	GO:0030048
GeneOntologyBiologicalProcess	negative regulation of low-density lipoprotein receptor activity	ABCA2 ADIPOQ	4.73e-04	8	86	2	GO:1905598
GeneOntologyBiologicalProcess	sequestering of iron ion	FTH1 FTMT	4.73e-04	8	86	2	GO:0097577
GeneOntologyBiologicalProcess	cardiac muscle cell action potential	SCN3A SCN4A FGF13 RYR2	4.82e-04	87	86	4	GO:0086001
GeneOntologyBiologicalProcess	monoatomic ion transport	ATP6V1A TRPV1 TRPM3 SCN3A SCN4A FTH1 SLCO3A1 FTMT CCR5 FGF13 FGF14 ATP13A3 MMP9 RYR2 SLC6A14	5.15e-04	1374	86	15	GO:0006811
GeneOntologyBiologicalProcess	carbohydrate derivative metabolic process	ATP6V1A AMPD3 MYH8 ABCA2 TMTC4 GALNT8 CHST9 EXT1 POMT1 HSD11B1 ELOVL6 UST HACD1 ALG13	5.19e-04	1226	86	14	GO:1901135
GeneOntologyBiologicalProcess	monoatomic cation transmembrane transport	ATP6V1A TRPV1 TRPM3 SCN3A SCN4A CCR5 FGF13 FGF14 ATP13A3 MMP9 RYR2 SLC6A14	5.21e-04	942	86	12	GO:0098655
GeneOntologyCellularComponent	apical part of cell	FZD6 SPTBN5 ATP6V1A EGFR PSG4 SLCO3A1 HSD11B1 RAB14 SLC6A14 ABCB4	1.58e-04	592	86	10	GO:0045177
GeneOntologyCellularComponent	nuclear outer membrane-endoplasmic reticulum membrane network	FZD6 ABCG1 SPTSSA EGFR PIK3R1 EXT1 POMT1 HSD11B1 ELOVL6 RAB14 RNF139 HERPUD1 HACD1 RYR2 ALG13	3.10e-04	1327	86	15	GO:0042175
GeneOntologyCellularComponent	spectrin	SPTBN5 SPTBN1	5.91e-04	9	86	2	GO:0008091
GeneOntologyCellularComponent	Golgi membrane	ATP6V1A ABCG1 EGFR GALNT8 CHST9 EXT1 GPR108 RAB14 UST ABCB4	7.46e-04	721	86	10	GO:0000139
GeneOntologyCellularComponent	endoplasmic reticulum membrane	FZD6 ABCG1 SPTSSA EGFR PIK3R1 EXT1 POMT1 HSD11B1 ELOVL6 RNF139 HERPUD1 HACD1 RYR2 ALG13	7.69e-04	1293	86	14	GO:0005789
GeneOntologyCellularComponent	endoplasmic reticulum subcompartment	FZD6 ABCG1 SPTSSA EGFR PIK3R1 EXT1 POMT1 HSD11B1 ELOVL6 RNF139 HERPUD1 HACD1 RYR2 ALG13	8.05e-04	1299	86	14	GO:0098827
GeneOntologyCellularComponent	apical plasma membrane	FZD6 ATP6V1A EGFR PSG4 SLCO3A1 RAB14 SLC6A14 ABCB4	8.87e-04	487	86	8	GO:0016324
Domain	ABC_transporter_CS	ABCG1 ABCA2 ABCD3 ABCB4	4.10e-05	42	86	4	IPR017871
Domain	AAA+_ATPase	ABCG1 ABCA2 ABCD3 KATNA1 SNRNP200 ABCB4	5.36e-05	144	86	6	IPR003593
Domain	AAA	ABCG1 ABCA2 ABCD3 KATNA1 SNRNP200 ABCB4	5.36e-05	144	86	6	SM00382
Domain	EST1	SMG5 SMG6	6.27e-05	3	86	2	PF10374
Domain	EST1_DNA_bind	SMG5 SMG6	6.27e-05	3	86	2	PF10373
Domain	EST1	SMG5 SMG6	6.27e-05	3	86	2	IPR019458
Domain	LAMININ_IVB	LAMB4 LAMB1	6.27e-05	3	86	2	PS51116
Domain	Laminin_IV_B	LAMB4 LAMB1	6.27e-05	3	86	2	IPR013015
Domain	DNA/RNA-bd_Est1-type	SMG5 SMG6	6.27e-05	3	86	2	IPR018834
Domain	ABC_tran	ABCG1 ABCA2 ABCD3 ABCB4	6.99e-05	48	86	4	PF00005
Domain	ABC_TRANSPORTER_2	ABCG1 ABCA2 ABCD3 ABCB4	6.99e-05	48	86	4	PS50893
Domain	ABC_TRANSPORTER_1	ABCG1 ABCA2 ABCD3 ABCB4	7.58e-05	49	86	4	PS00211
Domain	ABC_transporter-like	ABCG1 ABCA2 ABCD3 ABCB4	8.21e-05	50	86	4	IPR003439
Domain	FERRITIN_1	FTH1 FTMT	1.25e-04	4	86	2	PS00540
Domain	Ferritin-like_diiron	FTH1 FTMT	1.25e-04	4	86	2	IPR009040
Domain	FERRITIN_2	FTH1 FTMT	1.25e-04	4	86	2	PS00204
Domain	Ferritin	FTH1 FTMT	1.25e-04	4	86	2	IPR001519
Domain	FERRITIN_LIKE	FTH1 FTMT	1.25e-04	4	86	2	PS50905
Domain	PIN_4	SMG5 SMG6	1.25e-04	4	86	2	PF13638
Domain	Ferritin	FTH1 FTMT	1.25e-04	4	86	2	PF00210
Domain	Ferritin_DPS_dom	FTH1 FTMT	1.25e-04	4	86	2	IPR008331
Domain	Ferritin_CS	FTH1 FTMT	1.25e-04	4	86	2	IPR014034
Domain	P-loop_NTPase	ATP6V1A PSTK MYH8 ABCG1 ABCA2 EP400 ABCD3 KATNA1 RAB14 UST SNRNP200 AGAP1 ABCB4	1.28e-04	848	86	13	IPR027417
Domain	Ion_trans_dom	TRPV1 TRPM3 SCN3A SCN4A RYR2	1.82e-04	114	86	5	IPR005821
Domain	Ion_trans	TRPV1 TRPM3 SCN3A SCN4A RYR2	1.82e-04	114	86	5	PF00520
Domain	-	FTH1 FTMT	2.08e-04	5	86	2	1.20.1260.10
Domain	Ferritin-rel	FTH1 FTMT	3.11e-04	6	86	2	IPR012347
Domain	PINc	SMG5 SMG6	3.11e-04	6	86	2	SM00670
Domain	PIN_dom	SMG5 SMG6	3.11e-04	6	86	2	IPR002716
Domain	IQ	MYH8 SCN3A SCN4A UBE3C	3.22e-04	71	86	4	PF00612
Domain	IQ	MYH8 SCN3A SCN4A UBE3C	5.32e-04	81	86	4	SM00015
Domain	Laminin_EGF	LAMB4 MEGF6 LAMB1	5.55e-04	35	86	3	PF00053
Domain	EGF_Lam	LAMB4 MEGF6 LAMB1	5.55e-04	35	86	3	SM00180
Domain	-	ATP6V1A PSTK ABCG1 ABCA2 EP400 ABCD3 KATNA1 RAB14 SNRNP200 AGAP1 ABCB4	6.13e-04	746	86	11	3.40.50.300
Domain	Laminin_EGF	LAMB4 MEGF6 LAMB1	7.08e-04	38	86	3	IPR002049
Domain	TPR-like_helical_dom	PSMD6 TMTC4 EIF3L SMG5 TTK SMG6	7.23e-04	233	86	6	IPR011990
Domain	PH_dom-spectrin-type	SPTBN5 SPTBN1	7.39e-04	9	86	2	IPR001605
Domain	IQ_motif_EF-hand-BS	MYH8 SCN3A SCN4A UBE3C	7.92e-04	90	86	4	IPR000048
Domain	IQ	MYH8 SCN3A SCN4A UBE3C	8.96e-04	93	86	4	PS50096
Domain	Na_channel_asu	SCN3A SCN4A	9.21e-04	10	86	2	IPR001696
Domain	MIR	POMT1 RYR2	9.21e-04	10	86	2	PS50919
Domain	MIR	POMT1 RYR2	9.21e-04	10	86	2	PF02815
Domain	MIR	POMT1 RYR2	9.21e-04	10	86	2	SM00472
Domain	MIR_motif	POMT1 RYR2	9.21e-04	10	86	2	IPR016093
Domain	Na_trans_assoc	SCN3A SCN4A	9.21e-04	10	86	2	IPR010526
Domain	Na_trans_assoc	SCN3A SCN4A	9.21e-04	10	86	2	PF06512
Domain	Sulfotransfer_2	CHST9 UST	1.34e-03	12	86	2	PF03567
Domain	Sulfotransferase	CHST9 UST	1.34e-03	12	86	2	IPR005331
Domain	Ferritin-like_SF	FTH1 FTMT	1.84e-03	14	86	2	IPR009078
Domain	Laminin_N	LAMB4 LAMB1	2.41e-03	16	86	2	IPR008211
Domain	LAMININ_NTER	LAMB4 LAMB1	2.41e-03	16	86	2	PS51117
Domain	Laminin_N	LAMB4 LAMB1	2.41e-03	16	86	2	PF00055
Domain	LamNT	LAMB4 LAMB1	2.41e-03	16	86	2	SM00136
Domain	FGF	FGF13 FGF14	4.56e-03	22	86	2	SM00442
Domain	FGF	FGF13 FGF14	4.56e-03	22	86	2	PF00167
Domain	HBGF_FGF	FGF13 FGF14	4.56e-03	22	86	2	PS00247
Domain	Fibroblast_GF_fam	FGF13 FGF14	4.56e-03	22	86	2	IPR002209
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	PSMD6 CUL1 ATP6V1A TRPV1 ABCG1 ABCA2 TRPM3 FTH1 ABCD3 SLCO3A1 FTMT RYR2 SLC6A14 ABCB4	1.40e-05	681	76	14	MM14985
Pathway	REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS	SPTBN5 SPTBN1 SCN3A SCN4A	2.20e-05	31	76	4	M877
Pathway	REACTOME_PHASE_0_RAPID_DEPOLARISATION	SCN3A SCN4A FGF13 FGF14	2.50e-05	32	76	4	M27455
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	PSMD6 CUL1 ATP6V1A TRPV1 ABCG1 ABCA2 TRPM3 FTH1 ABCD3 SLCO3A1 FTMT RYR2 SLC6A14 ABCB4	3.33e-05	736	76	14	M27287
Pathway	REACTOME_L1CAM_INTERACTIONS	SPTBN5 EGFR SPTBN1 SCN3A SCN4A LAMB1	4.73e-05	121	76	6	M872
Pathway	KEGG_ABC_TRANSPORTERS	ABCG1 ABCA2 ABCD3 ABCB4	8.99e-05	44	76	4	M11911
Pathway	REACTOME_ABC_TRANSPORTERS_IN_LIPID_HOMEOSTASIS	ABCG1 ABCA2 ABCD3	9.70e-05	17	76	3	MM14552
Pathway	REACTOME_ABC_TRANSPORTERS_IN_LIPID_HOMEOSTASIS	ABCG1 ABCA2 ABCD3	1.16e-04	18	76	3	M524
Pathway	REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT	PSMD6 ABCG1 ABCA2 ABCD3 ABCB4	1.92e-04	99	76	5	MM14986
Pathway	REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT	PSMD6 ABCG1 ABCA2 ABCD3 ABCB4	2.31e-04	103	76	5	M758
Pathway	REACTOME_IRON_UPTAKE_AND_TRANSPORT	CUL1 ATP6V1A FTH1 FTMT	2.32e-04	56	76	4	MM15638
Pathway	REACTOME_IRON_UPTAKE_AND_TRANSPORT	CUL1 ATP6V1A FTH1 FTMT	2.65e-04	58	76	4	M962
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_USP8_TO_EGFR_ERK_ACTH_SIGNALING_PATHWAY	USP8 EGFR	2.84e-04	5	76	2	M49028
Pathway	KEGG_PATHWAYS_IN_CANCER	FZD6 LAMB4 EGFR PIK3R1 LAMB1 FGF13 FGF14 MMP9	3.53e-04	325	76	8	M12868
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	USP8 NLN TMTC4 TM9SF3 SLC19A2 EXT1 ATP13A3 POMT1 UBE3C ATE1 ELOVL6 RAB14 DCBLD2 ALG13	3.27e-07	1061	86	14	33845483
Pubmed	Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations.	ABCG1 ADIPOQ PIK3R1 ABCD3 ELOVL6 MMP9 ABCB4	3.02e-06	250	86	7	18660489
Pubmed	MMP-9 activity is increased by adiponectin in primary human hepatocytes but even negatively correlates with serum adiponectin in a rodent model of non-alcoholic steatohepatitis.	ADIPOQ MMP9	6.04e-06	2	86	2	21791204
Pubmed	C-C chemokine receptor 5 on pulmonary fibrocytes facilitates migration and promotes metastasis via matrix metalloproteinase 9.	CCR5 MMP9	6.04e-06	2	86	2	18535183
Pubmed	Microglial-to-neuronal CCR5 signaling regulates autophagy in neurodegeneration.	CCR5 FGF14	6.04e-06	2	86	2	37105172
Pubmed	Unique iron binding and oxidation properties of human mitochondrial ferritin: a comparative analysis with Human H-chain ferritin.	FTH1 FTMT	6.04e-06	2	86	2	15755449
Pubmed	Increased co-expression of macrophage migration inhibitory factor and matrix metalloproteinase 9 is associated with tumor recurrence of meningioma.	MMP9 HERPUD1	6.04e-06	2	86	2	23372434
Pubmed	Tissue-specific expression of ferritin H regulates cellular iron homoeostasis in vivo.	FTH1 FTMT	6.04e-06	2	86	2	16448386
Pubmed	Structures of the PIN domains of SMG6 and SMG5 reveal a nuclease within the mRNA surveillance complex.	SMG5 SMG6	6.04e-06	2	86	2	17053788
Pubmed	GALNT8 suppresses breast cancer cell metastasis potential by regulating EGFR O-GalNAcylation.	EGFR GALNT8	6.04e-06	2	86	2	35220009
Pubmed	Association of tyrosine phosphatase epsilon with microtubules inhibits phosphatase activity and is regulated by the epidermal growth factor receptor.	PTPRE EGFR	6.04e-06	2	86	2	17709387
Pubmed	Regulation of epidermal growth factor receptor down-regulation by UBPY-mediated deubiquitination at endosomes.	USP8 EGFR	6.04e-06	2	86	2	16120644
Pubmed	Polarized localization of voltage-gated Na+ channels is regulated by concerted FGF13 and FGF14 action.	FGF13 FGF14	6.04e-06	2	86	2	27044086
Pubmed	EGFR and MMP-9 are associated with neointimal hyperplasia in systemic-to-pulmonary shunts in children with complex cyanotic heart disease.	EGFR MMP9	6.04e-06	2	86	2	36867212
Pubmed	FGF13 enhances the function of TRPV1 by stabilizing microtubules and regulates acute and chronic itch.	TRPV1 FGF13	6.04e-06	2	86	2	38733310
Pubmed	Ubiquitin-specific protease 8 is a novel prognostic marker in early-stage lung adenocarcinoma.	USP8 EGFR	6.04e-06	2	86	2	28544031
Pubmed	Inhibition of Ubiquitin-specific Peptidase 8 Suppresses Growth of Gefitinib-resistant Non-small Cell Lung Cancer Cells by Inducing Apoptosis.	USP8 EGFR	6.04e-06	2	86	2	25853104
Pubmed	Reaction of plasma adiponectin level in non-small cell lung cancer patients treated with EGFR-TKIs.	ADIPOQ EGFR	6.04e-06	2	86	2	23909081
Pubmed	UBPY-mediated epidermal growth factor receptor (EGFR) de-ubiquitination promotes EGFR degradation.	USP8 EGFR	6.04e-06	2	86	2	17121848
Pubmed	EGF receptor kinase suppresses ciliogenesis through activation of USP8 deubiquitinase.	USP8 EGFR	6.04e-06	2	86	2	29472535
Pubmed	Transient receptor potential vanilloid 1 promotes EGFR ubiquitination and modulates EGFR/MAPK signalling in pancreatic cancer cells.	TRPV1 EGFR	6.04e-06	2	86	2	31907951
Pubmed	Nav1.3 and FGF14 are primary determinants of the TTX-sensitive sodium current in mouse adrenal chromaffin cells.	SCN3A FGF14	6.04e-06	2	86	2	33651884
Pubmed	Splicing factor Srsf5 deletion disrupts alternative splicing and causes noncompaction of ventricular myocardium.	MYH8 MYOM1 MMP9	9.68e-06	17	86	3	34622152
Pubmed	Recurrent gain-of-function USP8 mutations in Cushing's disease.	USP8 EGFR	1.81e-05	3	86	2	25675982
Pubmed	EGFR signaling downstream of EGF regulates migration, invasion, and MMP secretion of immortalized cells derived from human ameloblastoma.	EGFR MMP9	1.81e-05	3	86	2	25099616
Pubmed	Transient receptor potential type vanilloid 1 suppresses skin carcinogenesis.	TRPV1 EGFR	1.81e-05	3	86	2	19155296
Pubmed	Gene expression analysis of an EGFR indirectly related pathway identified PTEN and MMP9 as reliable diagnostic markers for human glial tumor specimens.	EGFR MMP9	1.81e-05	3	86	2	19657395
Pubmed	Inflammation-induced hepatocellular carcinoma is dependent on CCR5 in mice.	CCR5 ABCB4	1.81e-05	3	86	2	23526353
Pubmed	TRPM3 is a nociceptor channel involved in the detection of noxious heat.	TRPV1 TRPM3	1.81e-05	3	86	2	21555074
Pubmed	Diacylglycerol kinase delta and protein kinase C(alpha) modulate epidermal growth factor receptor abundance and degradation through ubiquitin-specific protease 8.	USP8 EGFR	1.81e-05	3	86	2	20064931
Pubmed	Protein expression and significance of VEGF, EGFR and MMP-9 in non-small cell lung carcinomas.	EGFR MMP9	1.81e-05	3	86	2	22126484
Pubmed	Circulating fibrocytes prepare the lung for cancer metastasis by recruiting Ly-6C+ monocytes via CCL2.	CCR5 MMP9	1.81e-05	3	86	2	23536638
Pubmed	Pro-MMP-9 upregulation in HT1080 cells expressing CD9 is regulated by epidermal growth factor receptor.	EGFR MMP9	1.81e-05	3	86	2	24246676
Pubmed	The interplay between AR, EGF receptor and MMP-9 signaling pathways in invasive prostate cancer.	EGFR MMP9	1.81e-05	3	86	2	30134822
Pubmed	A TRP channel trio mediates acute noxious heat sensing.	TRPV1 TRPM3	1.81e-05	3	86	2	29539642
Pubmed	Interaction between dual specificity phosphatase-1 and cullin-1 attenuates alcohol-related liver disease by restoring p62-mediated mitophagy.	CUL1 ABCB4	1.81e-05	3	86	2	37063418
Pubmed	Activation of EGFR promotes squamous carcinoma SCC10A cell migration and invasion via inducing EMT-like phenotype change and MMP-9-mediated degradation of E-cadherin.	EGFR MMP9	1.81e-05	3	86	2	21557297
Pubmed	A human homolog of yeast Est1 associates with telomerase and uncaps chromosome ends when overexpressed.	SMG5 SMG6	1.81e-05	3	86	2	12676087
Pubmed	Conditional deletion of ferritin H in mice induces loss of iron storage and liver damage.	FTH1 FTMT	1.81e-05	3	86	2	19492434
Pubmed	FGF13 Selectively Regulates Heat Nociception by Interacting with Nav1.7.	TRPV1 FGF13	1.81e-05	3	86	2	28162808
Pubmed	Clinical significance of levels of molecular biological markers in zones of invasive front-line of colorectal cancer.	LAMB1 MMP9	1.81e-05	3	86	2	19526105
Pubmed	p85α promotes nucleolin transcription and subsequently enhances EGFR mRNA stability and EGF-induced malignant cellular transformation.	EGFR PIK3R1	1.81e-05	3	86	2	26918608
Pubmed	CCL5/CCR5 axis promotes the motility of human oral cancer cells.	CCR5 MMP9	1.81e-05	3	86	2	19334035
Pubmed	Matrix metalloproteinases 2 and 9 mediate epidermal growth factor receptor transactivation by gonadotropin-releasing hormone.	EGFR MMP9	1.81e-05	3	86	2	12963732
Pubmed	Upregulation of TRPM3 in nociceptors innervating inflamed tissue.	TRPV1 TRPM3	1.81e-05	3	86	2	32880575
Pubmed	MiR-129 regulates MMP9 to control metastasis of non-small cell lung cancer.	EGFR MMP9	1.81e-05	3	86	2	25716201
Pubmed	Activation of TRPM3 by a potent synthetic ligand reveals a role in peptide release.	TRPV1 TRPM3	1.81e-05	3	86	2	25733887
Pubmed	METTL3 protects METTL14 from STUB1-mediated degradation to maintain m6 A homeostasis.	PSMD6 SPTBN1 EIF3L ABCD3 SNRNP200 SMG6	2.43e-05	231	86	6	36597993
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	PSMD6 CUL1 ATP6V1A SPTBN1 EIF3L ABCD3 HAT1 UBE3C SNRNP200	2.91e-05	638	86	9	33239621
Pubmed	Obesity-related polymorphisms and their associations with the ability to regulate fat oxidation in obese Europeans: the NUGENOB study.	ADIPOQ HSD11B1 SLC6A14	3.23e-05	25	86	3	19876004
Pubmed	Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2.	SPTBN5 EGFR SPTBN1	3.23e-05	25	86	3	8493579
Pubmed	Essential role of ubiquitin-specific protease 8 for receptor tyrosine kinase stability and endocytic trafficking in vivo.	USP8 EGFR	3.61e-05	4	86	2	17452457
Pubmed	EGFR phosphorylation of DCBLD2 recruits TRAF6 and stimulates AKT-promoted tumorigenesis.	EGFR DCBLD2	3.61e-05	4	86	2	25061874
Pubmed	Apoptosis induced by knockdown of uPAR and MMP-9 is mediated by inactivation of EGFR/STAT3 signaling in medulloblastoma.	EGFR MMP9	3.61e-05	4	86	2	22984561
Pubmed	SMG7 is a 14-3-3-like adaptor in the nonsense-mediated mRNA decay pathway.	SMG5 SMG6	3.61e-05	4	86	2	15721257
Pubmed	Association of 1166A>C AT1R, -1562C>T MMP-9, ACE I/D, and CCR5Δ32 Polymorphisms with Abdominal Aortic Aneurysm in Croatian Patients.	CCR5 MMP9	3.61e-05	4	86	2	27533781
Pubmed	HLA class I loss in metachronous metastases prevents continuous T cell recognition of mutated neoantigens in a human melanoma model.	MMS22L HERPUD1	3.61e-05	4	86	2	28423700
Pubmed	SH2 domains of the p85 alpha subunit of phosphatidylinositol 3-kinase regulate binding to growth factor receptors.	EGFR PIK3R1	3.61e-05	4	86	2	1372092
Pubmed	Immunohistochemical study of MMP-2, MMP-9, EGFR and IL-8 in decidual and trophoblastic specimens of recurrent pregnancy loss cases.	EGFR MMP9	3.61e-05	4	86	2	37258409
Pubmed	Functional conservation of the telomerase protein Est1p in humans.	SMG5 SMG6	3.61e-05	4	86	2	12699629
Pubmed	ADAM17 targets MMP-2 and MMP-9 via EGFR-MEK-ERK pathway activation to promote prostate cancer cell invasion.	EGFR MMP9	3.61e-05	4	86	2	22200661
Pubmed	The Usp8 deubiquitination enzyme is post-translationally modified by tyrosine and serine phosphorylation.	USP8 EGFR	3.61e-05	4	86	2	23333852
Pubmed	Regulation of cellular immortalization and steady-state levels of the telomerase reverse transcriptase through its carboxy-terminal domain.	SMG5 SMG6	3.61e-05	4	86	2	16507993
Pubmed	A Fra-1-dependent, matrix metalloproteinase driven EGFR activation promotes human lung epithelial cell motility and invasion.	EGFR MMP9	3.61e-05	4	86	2	18288638
Pubmed	Mutations in the deubiquitinase gene USP8 cause Cushing's disease.	USP8 EGFR	3.61e-05	4	86	2	25485838
Pubmed	The CysLT2R receptor mediates leukotriene C4-driven acute and chronic itch.	CYSLTR2 TRPV1	3.61e-05	4	86	2	33753496
Pubmed	Phospho-dependent and phospho-independent interactions of the helicase UPF1 with the NMD factors SMG5-SMG7 and SMG6.	SMG5 SMG6	3.61e-05	4	86	2	25013172
Pubmed	Brain beta spectrin isoform 235 (Spnb-2) maps to mouse chromosome 11.	EGFR SPTBN1	3.61e-05	4	86	2	1638088
Pubmed	ABCG1 (ABC8), the human homolog of the Drosophila white gene, is a regulator of macrophage cholesterol and phospholipid transport.	ABCG1 ABCA2	3.61e-05	4	86	2	10639163
Pubmed	Osteopontin is linked to p65 and MMP-9 expression in pulmonary adenocarcinoma but not in malignant pleural mesothelioma.	EGFR MMP9	3.61e-05	4	86	2	17493236
Pubmed	Transforming growth factor-β-induced protein (TGFBI) suppresses mesothelioma progression through the Akt/mTOR pathway.	EGFR PIK3R1	3.61e-05	4	86	2	21701776
Pubmed	The kinase domain and membrane localization determine intracellular interactions between epidermal growth factor receptors.	EGFR PIK3R1	3.61e-05	4	86	2	7531698
Pubmed	Inhibition of matrix metalloproteinase-9 attenuated neural progenitor cell migration after photothrombotic ischemia.	EGFR MMP9	3.61e-05	4	86	2	18616932
Pubmed	Src phosphorylation of the epidermal growth factor receptor at novel sites mediates receptor interaction with Src and P85 alpha.	EGFR PIK3R1	3.61e-05	4	86	2	7797556
Pubmed	Insulin receptor substrate is a mediator of phosphoinositide 3-kinase activation in quiescent pancreatic cancer cells.	EGFR PIK3R1	3.61e-05	4	86	2	16230374
Pubmed	An anchor site-type defect in human telomerase that disrupts telomere length maintenance and cellular immortalization.	SMG5 SMG6	3.61e-05	4	86	2	15857955
Pubmed	PIM2 Induced COX-2 and MMP-9 expression in macrophages requires PI3K and Notch1 signaling.	PIK3R1 MMP9	3.61e-05	4	86	2	19290049
Pubmed	PEA3 is necessary for optimal epidermal growth factor receptor-stimulated matrix metalloproteinase expression and invasion of ovarian tumor cells.	EGFR MMP9	3.61e-05	4	86	2	17475671
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	PSMD6 ZNF609 SPTBN1 TM9SF3 EIF3L ABCD3 HAT1 RAB14 RFX1 DCBLD2 SNRNP200 HERPUD1	4.01e-05	1203	86	12	29180619
Pubmed	High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men.	FZD6 ADIPOQ MGP EGFR EXT1 HSD11B1 MMP9	4.73e-05	383	86	7	19453261
Pubmed	Systematic protein-protein interaction mapping for clinically relevant human GPCRs.	GPR161 CYSLTR2 ABCA2 FTH1 HAT1 CCR5 RAB14 UST HERPUD1	5.77e-05	697	86	9	28298427
Pubmed	Increased proliferation and altered growth factor dependence of human mammary epithelial cells overexpressing the Gab2 docking protein.	EGFR PIK3R1	6.01e-05	5	86	2	16253990
Pubmed	Synergistic inhibition of cell migration by tetraspanin CD82 and gangliosides occurs via the EGFR or cMet-activated Pl3K/Akt signalling pathway.	EGFR PIK3R1	6.01e-05	5	86	2	23968914
Pubmed	Dominance of ErbB-1 heterodimers in lung epithelial cells overexpressing ErbB-2. Both ErbB-1 and ErbB-2 contribute significantly to tumorigenicity.	EGFR PIK3R1	6.01e-05	5	86	2	10572067
Pubmed	Formation of distinct signalling complexes involving phosphatidylinositol 3-kinase activity with stimulation of epidermal growth factor or insulin-like growth factor-I in human skin fibroblasts.	EGFR PIK3R1	6.01e-05	5	86	2	9886492
Pubmed	The Sensory Coding of Warm Perception.	TRPV1 TRPM3	6.01e-05	5	86	2	32208171
Pubmed	EGFR-Phosphorylated Platelet Isoform of Phosphofructokinase 1 Promotes PI3K Activation.	EGFR PIK3R1	6.01e-05	5	86	2	29677490
Pubmed	PI3K inhibition results in enhanced HER signaling and acquired ERK dependency in HER2-overexpressing breast cancer.	EGFR PIK3R1	6.01e-05	5	86	2	21278786
Pubmed	Hck enhances the adherence of lipopolysaccharide-stimulated macrophages via Cbl and phosphatidylinositol 3-kinase.	EGFR PIK3R1	6.01e-05	5	86	2	10799548
Pubmed	Structure/function characterization of micro-conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels.	SCN3A SCN4A	6.01e-05	5	86	2	17724025
Pubmed	Ion channel TRPV1-dependent activation of PTP1B suppresses EGFR-associated intestinal tumorigenesis.	TRPV1 EGFR	6.01e-05	5	86	2	25083990
Pubmed	HER2 kinase domain mutation results in constitutive phosphorylation and activation of HER2 and EGFR and resistance to EGFR tyrosine kinase inhibitors.	EGFR PIK3R1	6.01e-05	5	86	2	16843263
Pubmed	Expression of c-erbB receptors, MMPs and VEGF in squamous cell carcinoma of the head and neck.	EGFR MMP9	6.01e-05	5	86	2	15254682
Pubmed	Grb2-associated binder-1 mediates phosphatidylinositol 3-kinase activation and the promotion of cell survival by nerve growth factor.	EGFR PIK3R1	6.01e-05	5	86	2	9356464
Pubmed	14-3-3-dependent inhibition of the deubiquitinating activity of UBPY and its cancellation in the M phase.	USP8 EGFR	6.01e-05	5	86	2	17720156
Pubmed	Common variants of inflammatory cytokine genes are associated with risk of nephropathy in type 2 diabetes among Asian Indians.	CCR5 MMP9	6.01e-05	5	86	2	19357773
Pubmed	Epidermal growth factor receptor-mediated tissue transglutaminase overexpression couples acquired tumor necrosis factor-related apoptosis-inducing ligand resistance and migration through c-FLIP and MMP-9 proteins in lung cancer cells.	EGFR MMP9	6.01e-05	5	86	2	21525012
Pubmed	FAK integrates growth-factor and integrin signals to promote cell migration.	EGFR PIK3R1	6.01e-05	5	86	2	10806474
Pubmed	Regulation of epidermal growth factor receptor ubiquitination and trafficking by the USP8·STAM complex.	USP8 EGFR	6.01e-05	5	86	2	20736164
Pubmed	Epidermal growth factor receptor (EGFR)-mediated positive feedback of protein-tyrosine phosphatase epsilon (PTPepsilon) on ERK1/2 and AKT protein pathways is required for survival of human breast cancer cells.	PTPRE EGFR	6.01e-05	5	86	2	22117074
GeneFamily	EF-hand domain containing\|Spectrins	SPTBN5 SPTBN1	2.48e-04	7	63	2	1113
GeneFamily	Sodium voltage-gated channel alpha subunits	SCN3A SCN4A	4.23e-04	9	63	2	1203
GeneFamily	Laminin subunits	LAMB4 LAMB1	7.71e-04	12	63	2	626
Coexpression	LE_EGR2_TARGETS_DN	ABCA2 ADIPOQ PIK3R1 FTH1 SLCO3A1 ELOVL6	1.26e-06	107	84	6	M15148
Coexpression	LE_EGR2_TARGETS_DN	ABCA2 ADIPOQ PIK3R1 FTH1 SLCO3A1 ELOVL6	2.13e-06	117	84	6	MM1139
ToppCell	LA-02._Fibroblast_II\|LA / Chamber and Cluster_Paper	MGP EGFR SPTBN1 EXT1 FGF14 UST AGAP1	1.00e-07	194	86	7	234d1494c114cce77c619708bbcd8d5ce805f19b
ToppCell	LPS-antiTNF-Epithelial_alveolar-Mes-like-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MMS22L MGP MEGF6 CHST9 HSD11B1 TTK	3.40e-07	142	86	6	5690eee2ce1ecd02e34eac4193578bd13c4228b9
ToppCell	droplet-Liver-HEPATOCYTES-1m-Epithelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EGFR ABCD3 C1S HSD11B1 ELOVL6 ABCB4	9.10e-07	168	86	6	b98af4043dfa5dfa4413e482879fad88de484675
ToppCell	droplet-Liver-HEPATOCYTES-1m-Epithelial-hepatocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EGFR ABCD3 C1S HSD11B1 ELOVL6 ABCB4	9.10e-07	168	86	6	073b53d4cee6bc8c5c6fce51cf6cd9c316478f69
ToppCell	droplet-Liver-HEPATOCYTES\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EGFR ABCD3 C1S HSD11B1 ELOVL6 ABCB4	9.42e-07	169	86	6	f195467438c589f87224bde7da720dea072d110c
ToppCell	droplet-Liver-HEPATOCYTES-1m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EGFR ABCD3 C1S HSD11B1 ELOVL6 ABCB4	9.42e-07	169	86	6	7785cab967a33560830c394c918d6ce625103858
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ABCG1 EGFR LAMB1 SLCO3A1 CHST9 PHYHIPL	1.65e-06	186	86	6	5c4ffe4e4d5536ae9f8794277fe032c693e7dd56
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MGP MEGF6 PIK3R1 C1S FGF14 UST	1.75e-06	188	86	6	ce85a56ac27a6432421dde93a1bafa8b943244b9
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MGP SCN3A FTH1 LAMB1 C1S HSD11B1	1.92e-06	191	86	6	44a9a6768084dafc641ad455b65862bfd4cc0cb9
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MGP LAMB1 SLCO3A1 C1S UST RYR2	1.98e-06	192	86	6	f4fc2b0121f879bab2bee99dfb5ff2c3ca1c0e1b
ToppCell	LPS_only-Stromal_mesenchymal\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MGP LAMB1 SLCO3A1 C1S UST RYR2	1.98e-06	192	86	6	162d8b5858d150ecbbd1c9bf2b19c6c9cd50a158
ToppCell	LPS-IL1RA-Stromal_mesenchymal\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MGP LAMB1 SLCO3A1 C1S UST RYR2	1.98e-06	192	86	6	4e47a02007f562f29ba5910df64d32a0167d0bd1
ToppCell	LPS_only-Stromal_mesenchymal-Matrix_Fibroblast\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MGP LAMB1 SLCO3A1 C1S UST RYR2	1.98e-06	192	86	6	ee085e04d5dcfb657522484ed20b8c1ddeccfe0c
ToppCell	LA-02._Fibroblast_II\|World / Chamber and Cluster_Paper	MGP EGFR EXT1 FGF14 UST AGAP1	2.16e-06	195	86	6	a78b605b49acd8c9d68716266ca269dafcd910b9
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	ZNF609 EGFR SLCO3A1 EXT1 UST AGAP1	2.36e-06	198	86	6	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Ntn1_Npy2r\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	MEGF6 EGFR FGF13 HSD11B1 UST	1.01e-05	148	86	5	5e738522d4ad35e08bc4ff8c41b7bea38ec6ef95
ToppCell	facs-Liver-Hepatocytes\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EGFR SLC19A2 ABCD3 C1S ABCB4	1.30e-05	156	86	5	e2cda3ad4e5f44a80133864c5a38b766afb952ce
ToppCell	5'-Airway_Nasal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.0.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NLN FTH1 ATP13A3 MMP9 ABCB4	1.43e-05	159	86	5	4b840da854390f8285c219314cff4434d7ffcacc
ToppCell	5'-Airway_Nasal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NLN FTH1 ATP13A3 MMP9 ABCB4	1.43e-05	159	86	5	d9e535cf9a0a2302268f2897b010dcecc6426e41
ToppCell	5'-Airway_Nasal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NLN FTH1 ATP13A3 MMP9 ABCB4	1.43e-05	159	86	5	29999c87f5823f734e5cbf8ea8b729ec017db9b3
ToppCell	facs-Spleen-nan-3m-Lymphocytic-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYSLTR2 PIK3R1 CCR5 HSD11B1 UST	1.87e-05	168	86	5	74dc46738f1d0a448df6c9b8288b515d92697792
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MGP MEGF6 PHYHIP C1S UST	2.21e-05	174	86	5	9c916af5eebd932f67dc9117e1d26ff194a2ff2c
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MGP MEGF6 PHYHIP C1S UST	2.21e-05	174	86	5	bc71521f44a5fe013af42b06b5d1bd2446ecf3b5
ToppCell	droplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Periportal)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EGFR C1S HSD11B1 ELOVL6 ABCB4	2.27e-05	175	86	5	5c38d4b6c03473d841e6203a7efaa6dcb2d59386
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TRPV1 MGP SLC19A2 LAMB1 C1S	2.40e-05	177	86	5	bd602db857f37869ef76d14c05ef522c509f08ee
ToppCell	356C-Fibroblasts-Fibroblast-G\|356C / Donor, Lineage, Cell class and subclass (all cells)	MGP LAMB1 C1S HSD11B1 RYR2	2.40e-05	177	86	5	8220cc2fc0ee8764a67a3be51d75248be2453040
ToppCell	356C-Fibroblasts-Fibroblast-G-\|356C / Donor, Lineage, Cell class and subclass (all cells)	MGP LAMB1 C1S HSD11B1 RYR2	2.40e-05	177	86	5	7617270f49cd6b7ba66db72d20560cee985012b2
ToppCell	10x5'v1-week_12-13-Mesenchymal_osteo-stroma-osteochondral_precursor\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	GPR161 EGFR ENTPD3 LAMB1 HSD11B1	2.53e-05	179	86	5	98c0c5c8034ae8a4b3ceea7fd1d0386ee5f89d09
ToppCell	human_hepatoblastoma-Tumor_cells-T6\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	CYSLTR2 TRPM3 FGF13 UST RYR2	2.53e-05	179	86	5	14fc8ccb6b215063d747643f47d780d2b237eb67
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF609 GPR22 PHYHIP FGF14 RYR2	2.60e-05	180	86	5	f6a2208960d0df1500c974cc44c3c054cd7475a9
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MGP LAMB1 C1S HSD11B1 RYR2	2.67e-05	181	86	5	b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCell	P28-Mesenchymal-mesenchymal_fibroblast\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	MGP FTH1 LAMB1 C1S HSD11B1	2.67e-05	181	86	5	091e7975badd1ffa463a8ec87908be20781ecfd6
ToppCell	P28-Mesenchymal\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	MGP FTH1 LAMB1 C1S HSD11B1	2.74e-05	182	86	5	69f9d44694fe4f55a971ae0ac5dc3e7448ee78f3
ToppCell	P28-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	MGP FTH1 LAMB1 C1S HSD11B1	2.89e-05	184	86	5	924400f47e6b2cdf7b0d538df75857935cf0209b
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MGP LAMB1 C1S HSD11B1 RYR2	3.04e-05	186	86	5	5473283fb95cee556b1f6934cf72169b676b5bcc
ToppCell	LA-01._Fibroblast_I\|World / Chamber and Cluster_Paper	MGP EGFR EXT1 FGF14 UST	3.12e-05	187	86	5	4ea486991f66c29728d127171a07b81404ec0b78
ToppCell	droplet-Bladder-Unstain-18m-Epithelial-bladder_mesenchymal_cell_(Scara5+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AMPD3 MGP SPTBN1 FTH1 C1S	3.12e-05	187	86	5	7beba2a5d5978f2ae7d8bde10815705cf2572211
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC-Vascular_SMC_1\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	MGP MEGF6 PHYHIP LAMB1 FGF13	3.12e-05	187	86	5	1aebf6fab40b96f2f5feb77a302bb805838fccf3
ToppCell	facs-Brain_Myeloid-Striatum-3m-Myeloid-nan\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	USP8 ABCG1 MGP TM9SF3 CCR5	3.28e-05	189	86	5	6dd4ec5ce4beb856f0d2d1654e3c4676d1d63736
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ABCG1 EGFR SLCO3A1 CHST9 PHYHIPL	3.28e-05	189	86	5	904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCell	droplet-Lung-immune-endo-depleted\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGP SCN3A LAMB1 C1S HSD11B1	3.28e-05	189	86	5	c3fb363bb0156ffb3367c200f548faebda64ab4a
ToppCell	facs-Lung-18m-Mesenchymal\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MGP SCN3A LAMB1 C1S HSD11B1	3.28e-05	189	86	5	bdf8db938aa0863c4fed6fa99dcffd63c8c20c31
ToppCell	droplet-Lung-immune-endo-depleted-3m\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGP SCN3A LAMB1 C1S HSD11B1	3.28e-05	189	86	5	2a2953f6b1b7d070d739dcaf7285fce6e097d9e4
ToppCell	facs-Lung-18m-Mesenchymal-fibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MGP SCN3A LAMB1 C1S HSD11B1	3.28e-05	189	86	5	40cbd679dc0548bf5207e1b033c0597886ad6fe1
ToppCell	facs-Brain_Myeloid-Striatum-3m-Myeloid\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	USP8 ABCG1 MGP TM9SF3 CCR5	3.28e-05	189	86	5	3ae479ec7e00c57127cbe51a398329b10ca9848c
ToppCell	facs-Brain_Myeloid-Striatum-3m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	USP8 ABCG1 MGP TM9SF3 CCR5	3.28e-05	189	86	5	875df61ee48baa5142ba4d2427bdec1c53e5a828
ToppCell	droplet-Lung-3m\|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MGP SCN3A LAMB1 C1S HSD11B1	3.28e-05	189	86	5	5a636e952da9b1fd26aa17f7b129054f2da322b5
ToppCell	facs-Brain_Myeloid-Striatum-3m\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	USP8 ABCG1 MGP TM9SF3 CCR5	3.28e-05	189	86	5	97ef5215d841ff366a3e3682cd9bd04100cbfde0
ToppCell	droplet-Lung-18m-Mesenchymal-fibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MGP SCN3A LAMB1 C1S HSD11B1	3.28e-05	189	86	5	e76dc36a01d8ad7590b3acc4c46abfcb76857448
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MGP MEGF6 C1S FGF14 UST	3.36e-05	190	86	5	efb757f11c2809e66ddb48a5c84f5433f111cb7c
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LAMB1 SLCO3A1 C1S UST RYR2	3.36e-05	190	86	5	45df8fee00f8949937863159d7aa042e72748d9b
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-A\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MGP EGFR FTH1 C1S HSD11B1	3.36e-05	190	86	5	ad0d9aed8c9c99551765d14730d70ebef1ea856b
ToppCell	droplet-Lung-18m-Mesenchymal\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MGP SCN3A LAMB1 C1S HSD11B1	3.36e-05	190	86	5	0b7200897b2c389632c9b1ee37e272b811555dbc
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast-alveolar_fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MGP SCN3A FTH1 LAMB1 HSD11B1	3.45e-05	191	86	5	509230f50568e5a8ecf08edc4d58f9e2aa96efe9
ToppCell	droplet-Lung-18m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MGP SCN3A LAMB1 C1S HSD11B1	3.45e-05	191	86	5	36467322096bc766cd777dae3bfb4e65511e492c
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MGP LAMB1 SLCO3A1 C1S RYR2	3.45e-05	191	86	5	b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCell	droplet-Lung-immune-endo-depleted-3m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGP SCN3A LAMB1 C1S HSD11B1	3.45e-05	191	86	5	a261f0738d974784bbdd60f23092bfbcca464459
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EGFR LAMB1 SLCO3A1 CHST9 PHYHIPL	3.45e-05	191	86	5	d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCell	facs-Lung-24m-Mesenchymal-fibroblast\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MGP SCN3A LAMB1 C1S HSD11B1	3.45e-05	191	86	5	094c9d3270fc1e487ccf10fb4936af5f081f6009
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ADIPOQ MGP MEGF6 PIK3R1 FGF14	3.45e-05	191	86	5	2c51850f5c559d665b8a27a12b75af9ed58dffe1
ToppCell	droplet-Lung-21m-Mesenchymal-fibroblast\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MGP SCN3A LAMB1 C1S HSD11B1	3.45e-05	191	86	5	8a73d2df079566fca4cbb5cdb85721c2e87134c8
ToppCell	droplet-Lung-18m-Mesenchymal-fibroblast-alveolar_fibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MGP SCN3A LAMB1 C1S HSD11B1	3.45e-05	191	86	5	94795daf05061baa3b72a1b01c9e940af86de044
ToppCell	droplet-Lung-immune-endo-depleted-3m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGP SCN3A LAMB1 C1S HSD11B1	3.45e-05	191	86	5	6594398cc8151c73696391a43ac110c10283dab1
ToppCell	droplet-Lung-1m-Mesenchymal-fibroblast\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MGP SCN3A LAMB1 C1S HSD11B1	3.45e-05	191	86	5	ce80f65bd24b1c4d2152bf45248449e7a1a97e56
ToppCell	facs-Lung-24m-Mesenchymal\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MGP SCN3A LAMB1 C1S HSD11B1	3.45e-05	191	86	5	ba02cbdfda6a94374a6472eb88499059979af472
ToppCell	facs-Lung-24m-Mesenchymal-fibroblast-alveolar_fibroblast\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MGP SCN3A LAMB1 C1S HSD11B1	3.45e-05	191	86	5	80484d39f34703a33b9bac09826b7a526e883cab
ToppCell	facs-Lung-18m-Mesenchymal-fibroblast-alveolar_fibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MGP SCN3A LAMB1 C1S HSD11B1	3.45e-05	191	86	5	d4f535b06ad483448ab692e9900c872c78cbed60
ToppCell	COPD-Endothelial-VE_Arterial\|Endothelial / Disease state, Lineage and Cell class	MGP EGFR EXT1 ATP13A3 HERPUD1	3.45e-05	191	86	5	ef16ad1c1cd2c0c0377957398c98775b62a81754
ToppCell	facs-Lung-24m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MGP SCN3A LAMB1 C1S HSD11B1	3.45e-05	191	86	5	5c4e4e9de14edfae072a2a2882220a31bebf51b2
ToppCell	droplet-Lung-1m-Mesenchymal-fibroblast-alveolar_fibroblast\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MGP SCN3A LAMB1 C1S HSD11B1	3.45e-05	191	86	5	d04e6292fef189b8d8ed0f4b0c310b2b250fd30e
ToppCell	5'-Adult-LymphNode-Mesenchymal\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MGP EGFR SLC19A2 LAMB1 C1S	3.45e-05	191	86	5	054e9a79bd1486fd812bc7418fb091664fe3a646
ToppCell	facs-Lung-18m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MGP SCN3A LAMB1 C1S HSD11B1	3.45e-05	191	86	5	b5210de890d338602857b5907135705a507bc2b0
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MGP SCN3A FTH1 LAMB1 HSD11B1	3.45e-05	191	86	5	0b3dbbc35d9970d3c749aef16dda59886b960e3d
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MGP EGFR LAMB1 C1S HSD11B1	3.45e-05	191	86	5	997abf0cc5873bed0372c4a333ed307fa72774d2
ToppCell	droplet-Lung-21m-Mesenchymal\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MGP SCN3A LAMB1 C1S HSD11B1	3.45e-05	191	86	5	10a9db1caa0fdb51ace8537f42b2c66f7c97e0f5
ToppCell	5'-Adult-LymphNode-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MGP EGFR SLC19A2 LAMB1 C1S	3.54e-05	192	86	5	9479e9859140ba98abfe88414de0b28fc2bf43b7
ToppCell	droplet-Lung-nan-18m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGP SCN3A LAMB1 C1S HSD11B1	3.54e-05	192	86	5	df56c3e3bb1aafc1126607f4426554c09c8c40cf
ToppCell	facs-BAT-Fat-24m-Mesenchymal-mesenchymal_progenitor\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGP EGFR LAMB1 C1S HSD11B1	3.54e-05	192	86	5	0b3161ce3add9f7457f4cfa5749dbb6501e3ad36
ToppCell	droplet-Lung-nan-18m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGP SCN3A LAMB1 C1S HSD11B1	3.54e-05	192	86	5	d22c1135867bcb9076435e2c6eb1cc1248990d0c
ToppCell	facs-BAT-Fat-24m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGP EGFR LAMB1 C1S HSD11B1	3.54e-05	192	86	5	61c7ec6171c519b2f3e9ce623669162c0c6ba9f5
ToppCell	RV-01._Fibroblast_I\|RV / Chamber and Cluster_Paper	MGP EGFR LAMB1 C1S UST	3.54e-05	192	86	5	356160b113c3305a61ceeaff33ce3c9da0be2878
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EGFR LAMB1 C1S UST DCBLD2	3.54e-05	192	86	5	beac6b3c191b11add8e39e8d04562b478ea8929e
ToppCell	droplet-Lung-nan-18m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGP SCN3A LAMB1 C1S HSD11B1	3.54e-05	192	86	5	c09966f4d63a739a56db4df7e0e0ee9ecacd21ad
ToppCell	facs-BAT-Fat-24m-Mesenchymal\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGP EGFR LAMB1 C1S HSD11B1	3.54e-05	192	86	5	24d682e3247a73d349e7776b9e564b6b57f4cb13
ToppCell	COVID-19-Heart-Fib_+_EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	MGP EGFR LAMB1 EXT1 AGAP1	3.54e-05	192	86	5	60b1312e84f6d6448365a952469c506c00b5fe93
ToppCell	facs-Lung-3m-Mesenchymal\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MGP EGFR LAMB1 C1S HSD11B1	3.54e-05	192	86	5	8df15085b35b86f39debd933284cb703c5dd63c2
ToppCell	5'-Adult-LymphNode-Mesenchymal-fibroblastic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MGP EGFR SLC19A2 LAMB1 C1S	3.54e-05	192	86	5	d7faa993f68e530ad55185505384ae155d36c222
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MGP LAMB1 SLCO3A1 C1S RYR2	3.54e-05	192	86	5	3d0cb19f037f604253d7d728689aeaa94251e92b
ToppCell	droplet-Limb_Muscle-nan-18m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EGFR FTH1 LAMB1 C1S HSD11B1	3.54e-05	192	86	5	2d9e2262f1342fe17735f21f733c029d1275e955
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF609 TRPM3 FGF13 EXT1 AGAP1	3.54e-05	192	86	5	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LAMB1 SLCO3A1 C1S UST RYR2	3.54e-05	192	86	5	deeecd26972241846b4cb998edf0c7a87ff0c4df
ToppCell	facs-Brain_Myeloid-Hippocampus-3m-Myeloid\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	USP8 MGP PIK3R1 TM9SF3 CCR5	3.62e-05	193	86	5	06b65110db974f4ef90d3511ff34428976a52c9c
ToppCell	BAL-Control-Myeloid-MoAM-MoAM3\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	AMPD3 PTPRE CCR5 ATP13A3 MMP9	3.62e-05	193	86	5	837c61408462c519912ecf3b83fdc72cd85fe88f
ToppCell	Control-Myeloid-MoAM3\|Control / Disease group,lineage and cell class （2021.01.30）	AMPD3 PTPRE CCR5 ATP13A3 MMP9	3.62e-05	193	86	5	97d2f12be43fc26efa84ac4c6119132928a123de
ToppCell	PND28-Mesenchymal-Mesenchymal_structural\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MGP SCN3A LAMB1 C1S HSD11B1	3.62e-05	193	86	5	ec81c1afdae2e0433a22c8c1fa1c6232526ff7e7
ToppCell	facs-Brain_Myeloid-Hippocampus-3m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	USP8 MGP PIK3R1 TM9SF3 CCR5	3.62e-05	193	86	5	9c16032bc03df8760ae199e8f19fdafa4c3f1827
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MGP FTH1 LAMB1 C1S HSD11B1	3.62e-05	193	86	5	a313541cedfcff8fb311b9bc60157359aa103830
ToppCell	droplet-Limb_Muscle-nan-18m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGP EGFR FTH1 C1S HSD11B1	3.62e-05	193	86	5	49600db68ed65cafc67bd45a285b364e4f5f88af
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MGP SCN3A LAMB1 C1S HSD11B1	3.62e-05	193	86	5	4c74a3f69b2cbdf139e7e66b44bd86869ac34dc0
ToppCell	facs-Lung-EPCAM-3m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGP SCN3A LAMB1 C1S HSD11B1	3.62e-05	193	86	5	027e098ad018e782287f84eee0f77551018f2196
Disease	Insulin Resistance	ADIPOQ EGFR PIK3R1 HSD11B1	2.90e-05	60	86	4	C0021655
Disease	Insulin Sensitivity	ADIPOQ EGFR PIK3R1 HSD11B1	2.90e-05	60	86	4	C0920563
Disease	coronary artery disease (biomarker_via_orthology)	CCR5 MMP9	5.02e-05	4	86	2	DOID:3393 (biomarker_via_orthology)
Disease	type 2 diabetes mellitus (biomarker_via_orthology)	ADIPOQ PIK3R1 CCR5 HSD11B1 MMP9	7.22e-05	147	86	5	DOID:9352 (biomarker_via_orthology)
Disease	response to silica exposure, pneumoconiosis	LAMB4 LAMB1	8.35e-05	5	86	2	EFO_0005853, MONDO_0015926
Disease	Alveolitis, Fibrosing	CYSLTR2 ADIPOQ LAMB1 MMP9	1.04e-04	83	86	4	C4721507
Disease	Pulmonary Fibrosis	CYSLTR2 ADIPOQ LAMB1 MMP9	1.14e-04	85	86	4	C0034069
Disease	Behcet's disease (is_marker_for)	ADIPOQ CCR5 MMP9	1.22e-04	33	86	3	DOID:13241 (is_marker_for)
Disease	allergic contact dermatitis (biomarker_via_orthology)	CCR5 MMP9	1.25e-04	6	86	2	DOID:3042 (biomarker_via_orthology)
Disease	epididymis-specific alpha-mannosidase measurement	MAN2B2 C1S	1.75e-04	7	86	2	EFO_0801577
Disease	cardiomyopathy (is_marker_for)	ADIPOQ MMP9	1.75e-04	7	86	2	DOID:0050700 (is_marker_for)
Disease	chronic obstructive pulmonary disease (is_marker_for)	ADIPOQ EGFR CCR5 MMP9	1.90e-04	97	86	4	DOID:3083 (is_marker_for)
Disease	dementia (is_marker_for)	ADIPOQ EGFR	2.32e-04	8	86	2	DOID:1307 (is_marker_for)
Disease	Coronavirus infectious disease (implicated_via_orthology)	EGFR CCR5	2.98e-04	9	86	2	DOID:0080599 (implicated_via_orthology)
Disease	generalized epilepsy with febrile seizures plus 2 (implicated_via_orthology)	SCN3A SCN4A	3.72e-04	10	86	2	DOID:0111294 (implicated_via_orthology)
Disease	Dravet syndrome (implicated_via_orthology)	SCN3A SCN4A	3.72e-04	10	86	2	DOID:0080422 (implicated_via_orthology)
Disease	pleural tuberculosis (is_marker_for)	CCR5 MMP9	3.72e-04	10	86	2	DOID:106 (is_marker_for)
Disease	multiple sclerosis (is_marker_for)	ADIPOQ CCR5 MMP9	4.00e-04	49	86	3	DOID:2377 (is_marker_for)
Disease	Inflammation	TRPV1 ADIPOQ MMP9 ABCB4	5.29e-04	127	86	4	C0021368
Disease	diabetic retinopathy (is_marker_for)	ADIPOQ EGFR MMP9	5.33e-04	54	86	3	DOID:8947 (is_marker_for)
Disease	endometrial carcinoma (is_implicated_in)	PIK3R1 POLE	5.44e-04	12	86	2	DOID:2871 (is_implicated_in)
Disease	generalized epilepsy with febrile seizures plus (implicated_via_orthology)	SCN3A SCN4A	5.44e-04	12	86	2	DOID:0060170 (implicated_via_orthology)
Disease	Congenital myopathy (disorder)	SCN4A HACD1	5.44e-04	12	86	2	C0270960
Disease	Candidemia	SPTBN5 SLCO3A1	5.44e-04	12	86	2	EFO_1001282
Disease	renal cell carcinoma (is_marker_for)	MGP EGFR PIK3R1 MMP9	5.45e-04	128	86	4	DOID:4450 (is_marker_for)
Disease	atrophic macular degeneration, age-related macular degeneration, wet macular degeneration	TRPM3 MMP9 HERPUD1	7.25e-04	60	86	3	EFO_0001365, EFO_0004683, EFO_1001492
Disease	Kawasaki disease (is_marker_for)	ADIPOQ MMP9	7.47e-04	14	86	2	DOID:13378 (is_marker_for)
Disease	pulmonary emphysema (is_marker_for)	CCR5 MMP9	7.47e-04	14	86	2	DOID:9675 (is_marker_for)
Disease	lysophosphatidylcholine measurement	FTH1 FGF14 HERPUD1	7.98e-04	62	86	3	EFO_0010224
Disease	rheumatoid arthritis (is_marker_for)	ADIPOQ PIK3R1 MMP9	1.09e-03	69	86	3	DOID:7148 (is_marker_for)
Disease	Mammary Neoplasms, Experimental	MGP EGFR PIK3R1 MMP9	1.11e-03	155	86	4	C0024668
Disease	Alcoholic Intoxication, Chronic	EGFR PIK3R1 SLCO3A1 MMP9 HERPUD1	1.14e-03	268	86	5	C0001973
Disease	osteoarthritis, knee	USP8 AMPD3 AGAP1 SMG6	1.19e-03	158	86	4	EFO_0004616
Disease	Malignant neoplasm of endometrium	EGFR POLE	1.25e-03	18	86	2	C0007103
Disease	Carcinoma in situ of endometrium	EGFR POLE	1.25e-03	18	86	2	C0346191
Disease	Sjogren's syndrome (is_implicated_in)	CCR5 MMP9	1.25e-03	18	86	2	DOID:12894 (is_implicated_in)
Disease	Colorectal Neoplasms	ABCG1 EGFR POLE ABCD3 ABCB4	1.32e-03	277	86	5	C0009404
Disease	cardiomyopathy (is_implicated_in)	ADIPOQ POMT1	1.39e-03	19	86	2	DOID:0050700 (is_implicated_in)
Disease	familial hyperlipidemia (biomarker_via_orthology)	ADIPOQ HSD11B1	1.39e-03	19	86	2	DOID:1168 (biomarker_via_orthology)
Disease	type 1 diabetes mellitus (biomarker_via_orthology)	EGFR CCR5	1.39e-03	19	86	2	DOID:9744 (biomarker_via_orthology)
Disease	glaucoma (is_marker_for)	CCR5 MMP9	1.54e-03	20	86	2	DOID:1686 (is_marker_for)
Disease	level of Phosphatidylcholine (16:0_18:2) in blood serum	FTH1 HERPUD1	1.54e-03	20	86	2	OBA_2045071
Disease	Glioma	EGFR PIK3R1 FTH1	2.12e-03	87	86	3	C0017638
Disease	systemic mastocytosis	ABCA2 MEGF6	2.41e-03	25	86	2	MONDO_0016586
Disease	interstitial lung disease (is_marker_for)	CCR5 MMP9	2.41e-03	25	86	2	DOID:3082 (is_marker_for)
Disease	cerebellum cortex volume change measurement, age at assessment	ABCG1 PIK3R1	2.61e-03	26	86	2	EFO_0008007, EFO_0021497
Disease	Adenocarcinoma of large intestine	EGFR PIK3R1 POLE	2.81e-03	96	86	3	C1319315

Protein segments in the cluster

Peptide	Gene	Start	Entry
AVYTRRKLDAVYYYM	SMG6	776	Q86US8
LTYTREDAYSMEYVY	EP400	2221	Q96L91
QKSDYMEYAGRQYYL	ALG13	481	Q9NP73
SFQTVYHYYSRMANY	AGAP1	151	Q9UPQ3
TYLQWMSYISYVRYG	ABCG1	591	P45844
YEEMLRFYSYYKQAT	ACBD4	36	Q8NC06
GLYYFAYHITVYMKD	ADIPOQ	156	Q15848
YYYYALAIVVMSIVS	ATP13A3	231	Q9H7F0
MDYQVSSPIYDINYY	CCR5	1	P51681
ILGLFMAYYYYSANE	HSD11B1	11	P28845
SYYLYYMYANIMVLN	AMPD3	556	Q01432
DIMQVSLYGYVYTLY	ENTPD3	241	O75355
YNYSYIFKYIIIGDM	RAB14	6	P61106
IYARQYYMQYLAATA	HERPUD1	176	Q15011
EEYLYRYGYTRVAEM	MMP9	46	P14780
DMQYTFIYQALLEYY	PTPRE	381	P23469
YHYFYMVTNTLFYVS	NTSR2	336	O95665
MAQSVQASRYLLYYY	MPC1L	91	P0DKB6
CQVTTYYYVGFAYLM	EIF3L	311	Q9Y262
DYGMRYYYQVYSILE	MMS22L	1166	Q6ZRQ5
NYDIIKTYHYLYLAM	FEM1B	266	Q9UK73
YNLKERYAAWMIYTY	MYH8	106	P13535
ENYYVIYSSMLYRQQ	FGF14	151	Q92915
EKYYYAVYDMVVRGN	LAMB1	256	P07942
SDAVATYYLYMKYVH	POLE	461	Q07864
MSAEGYQYRALYDYK	PIK3R1	1	P27986
GKILEEEMTRYAYYY	ABCB4	106	P21439
VFDEVYYGQYISFYM	POMT1	41	Q9Y6A1
NLELYASYVYLSMSY	FTH1	26	P02794
ASYVYLSMSYYFDRD	FTH1	31	P02794
YYSVCYSIVSLMYFI	FZD6	236	O60353
YGVHAVMYSYYALRA	ELOVL6	171	Q9H5J4
MYYENSYALAVLSNY	EGFR	111	P00533
FATVGYMTVYNYYVY	HAT1	216	O14929
YSMVLTGAAIYHKYY	EXT1	616	Q16394
RYMELYTHVYNYCTS	CUL1	41	Q13616
IMYYCHEFSSQNVYY	GALNT8	521	Q9NY28
FDYYYFLLITMASYI	HACD1	246	B0YJ81
VIRYTCEEPYYYMEN	C1S	381	P09871
YFLSYVPYMYVAIRE	ABCA2	821	Q9BZC7
YFYRNMTAQNYTYAI	MAN2B2	666	Q9Y2E5
EKTSQLSYYYMGFYI	ATE1	396	O95260
SVFENYYVTYSSMIY	FGF13	146	Q92913
IAIDRYYAVLYPMVY	GPR161	121	Q8N6U8
YALLGNYDSAMVYYQ	KATNA1	16	O75449
NDSLDKYYYALYEMI	LAMB4	246	A4D0S4
KYYYALYEMIVRGSC	LAMB4	251	A4D0S4
MVEHNYYVSAYRILY	DCBLD2	371	Q96PD2
NEYYTELGMYYHLLV	GPR22	201	Q99680
IWYKGQMTYLYHYIT	PSG4	66	Q00888
QMTYLYHYITSYVVD	PSG4	71	Q00888
YYSYIYSVVDLGMYQ	SLC19A2	141	O60779
DYDFLMQTSTYYYSV	RYR2	1416	Q92736
RYAMVYGYNAAYNRY	MGP	81	P08493
LELYASYVYLSMAYY	FTMT	86	Q8N4E7
SYVYLSMAYYFSRDD	FTMT	91	Q8N4E7
YELMDYKTFVTYTVY	PSMD6	211	Q15008
VCMYYTAVFYAYISP	OR13A1	266	Q8NGR1
HERRTVYYMGYRQVY	MEGF6	86	O75095
VYYMGYRQVYTTEAR	MEGF6	91	O75095
FYYSTRYVYLLVRHM	RNF139	201	Q8WU17
FYCMYTAYHYVILVI	PHYHIPL	271	Q96FC7
EQPQYEVNLYMYLYF	SCN4A	1261	P35499
LYDNVVYRYLYVSIA	SLCO3A1	616	Q9UIG8
LAGSKYYNVEAMYCY	SMG5	221	Q9UPR3
LYDEYMYYLIEHRVA	RFX1	881	P22670
HYYVMVICYVYFTRI	GPR108	446	Q9NPR9
YCMYTAYHYAILVLA	PHYHIP	226	Q92561
PVYEENLYMYLYFVI	SCN3A	1436	Q9NY46
FYYQYLLVTALYMLE	SPTSSA	16	Q969W0
DERSIMTYVSLYYHY	SPTBN5	266	Q9NRC6
KTYVYYIYGTDHQVY	SSUH2	346	Q9Y2M2
IITYVVTYYHYFSKM	SPTBN1	266	Q01082
YLYEEYLQAFTYYKM	ABCD3	161	P28288
ERQLIYDFYYLDYLM	CHST9	421	Q7L1S5
YSLYVNMYSSIYFLT	CYSLTR2	116	Q9NS75
LYYYMTQTEELKYSI	NLN	361	Q9BYT8
ILYQRMRYEYEFYHY	UST	336	Q9Y2C2
MRYEYEFYHYVKEQF	UST	341	Q9Y2C2
MLVRAVNYNYYYSLN	TMTC4	311	Q5T4D3
EMSAVYIEFTEYYYP	UHRF1BP1L	496	A0JNW5
VYCLYMIIFTMAAYY	TRPV1	441	Q8NER1
YTLAYIGYLMLFNYI	TRPM3	901	Q9HCF6
YQSMRYEVYQLARKY	PSTK	156	Q8IV42
NMYMQSLYYNQYAYV	ZNF609	966	O15014
LISYSKYMRALDEYY	ATP6V1A	451	P38606
SAASTAIYVYMYSFY	TM9SF3	521	Q9HD45
GMIAAYYYINYTTIE	SNRNP200	1816	O75643
YYYINYTTIELFSMS	SNRNP200	1821	O75643
IRLYDYEITDQYIYM	TTK	586	P33981
YYNVIIAYSLYYMFA	SLC6A14	131	Q9UN76
EERAYVLYMKYVTVY	USP8	56	P40818
YMIHNGYYRSLYLLI	UBE3C	201	Q15386
MGEYYEQYSAYVFVR	MYOM1	486	P52179