Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncytoskeletal protein binding

PROM1 ROCK1 DSTN PSTPIP1 KIF26B CFL1 CFL2 TPRN

1.25e-041099298GO:0008092
GeneOntologyMolecularFunctionactin filament binding

DSTN PSTPIP1 CFL1 CFL2

3.09e-04227294GO:0051015
GeneOntologyMolecularFunctionactin binding

DSTN PSTPIP1 CFL1 CFL2 TPRN

5.74e-04479295GO:0003779
GeneOntologyBiologicalProcessactin filament fragmentation

DSTN CFL1 CFL2

9.99e-094293GO:0030043
GeneOntologyBiologicalProcesspositive regulation of actin filament depolymerization

DSTN CFL1 CFL2

9.00e-0714293GO:0030836
GeneOntologyBiologicalProcessactin filament severing

DSTN CFL1 CFL2

2.01e-0618293GO:0051014
GeneOntologyBiologicalProcesspositive regulation of protein depolymerization

DSTN CFL1 CFL2

3.27e-0621293GO:1901881
GeneOntologyBiologicalProcessactin polymerization or depolymerization

KANK4 DSTN PSTPIP1 CFL1 CFL2

1.33e-05222295GO:0008154
GeneOntologyBiologicalProcesspositive regulation of protein-containing complex disassembly

DSTN CFL1 CFL2

2.57e-0541293GO:0043243
GeneOntologyBiologicalProcessregulation of actin filament organization

KANK4 ROCK1 DSTN CFL1 CFL2

5.61e-05300295GO:0110053
GeneOntologyBiologicalProcessactin filament organization

KANK4 ROCK1 DSTN PSTPIP1 CFL1 CFL2

6.43e-05509296GO:0007015
GeneOntologyBiologicalProcessregulation of actin filament depolymerization

DSTN CFL1 CFL2

8.51e-0561293GO:0030834
GeneOntologyBiologicalProcessregulation of actin polymerization or depolymerization

KANK4 DSTN CFL1 CFL2

1.05e-04177294GO:0008064
GeneOntologyBiologicalProcessactin filament depolymerization

DSTN CFL1 CFL2

1.08e-0466293GO:0030042
GeneOntologyBiologicalProcessregulation of actin filament length

KANK4 DSTN CFL1 CFL2

1.12e-04180294GO:0030832
GeneOntologyBiologicalProcessregulation of actin cytoskeleton organization

KANK4 ROCK1 DSTN CFL1 CFL2

1.79e-04384295GO:0032956
GeneOntologyBiologicalProcesscytokinesis

ROCK1 DSTN PSTPIP1 CFL1

1.82e-04204294GO:0000910
GeneOntologyBiologicalProcessregulation of anatomical structure size

KANK4 ROCK1 DSTN PPARD CFL1 CFL2

1.86e-04618296GO:0090066
GeneOntologyBiologicalProcessregulation of actin filament-based process

KANK4 ROCK1 DSTN CFL1 CFL2

3.29e-04438295GO:0032970
GeneOntologyBiologicalProcessregulation of supramolecular fiber organization

KANK4 ROCK1 DSTN CFL1 CFL2

3.29e-04438295GO:1902903
GeneOntologyBiologicalProcessregulation of protein depolymerization

DSTN CFL1 CFL2

4.25e-04105293GO:1901879
GeneOntologyBiologicalProcessphospholipid biosynthetic process

SLC44A2 SOCS6 PPARD CWH43

5.12e-04268294GO:0008654
GeneOntologyBiologicalProcessregulation of establishment of cell polarity

ROCK1 CFL1

5.61e-0425292GO:2000114
GeneOntologyBiologicalProcessregulation of actin filament bundle assembly

KANK4 ROCK1 CFL1

6.75e-04123293GO:0032231
GeneOntologyBiologicalProcessactin cytoskeleton organization

KANK4 ROCK1 DSTN PSTPIP1 CFL1 CFL2

7.53e-04803296GO:0030036
GeneOntologyBiologicalProcessregulation of establishment or maintenance of cell polarity

ROCK1 CFL1

8.10e-0430292GO:0032878
GeneOntologyBiologicalProcesspositive regulation of focal adhesion assembly

ROCK1 CFL1

8.65e-0431292GO:0051894
GeneOntologyBiologicalProcessprotein depolymerization

DSTN CFL1 CFL2

1.07e-03144293GO:0051261
GeneOntologyBiologicalProcessregulation of protein-containing complex disassembly

DSTN CFL1 CFL2

1.07e-03144293GO:0043244
GeneOntologyBiologicalProcessregulation of cytoskeleton organization

KANK4 ROCK1 DSTN CFL1 CFL2

1.16e-03579295GO:0051493
GeneOntologyBiologicalProcesspositive regulation of cell-substrate junction organization

ROCK1 CFL1

1.17e-0336292GO:0150117
GeneOntologyBiologicalProcessactin filament-based process

KANK4 ROCK1 DSTN PSTPIP1 CFL1 CFL2

1.46e-03912296GO:0030029
GeneOntologyBiologicalProcessnegative regulation of actin filament bundle assembly

KANK4 CFL1

1.82e-0345292GO:0032232
GeneOntologyBiologicalProcesssupramolecular fiber organization

KANK4 ROCK1 DSTN PSTPIP1 CFL1 CFL2

1.86e-03957296GO:0097435
GeneOntologyBiologicalProcessestablishment of cell polarity

ROCK1 KIF26B CFL1

1.93e-03177293GO:0030010
DomainADF/Cofilin

DSTN CFL1 CFL2

3.74e-093303IPR017904
DomainADF

DSTN CFL1 CFL2

4.45e-0710303SM00102
DomainCofilin_ADF

DSTN CFL1 CFL2

4.45e-0710303PF00241
DomainADF-H

DSTN CFL1 CFL2

4.45e-0710303IPR002108
DomainADF_H

DSTN CFL1 CFL2

4.45e-0710303PS51263
Domain-

DSTN CFL1 CFL2

7.40e-06243033.40.20.10
DomainADF-H/Gelsolin-like_dom

DSTN CFL1 CFL2

7.40e-0624303IPR029006
Domain-

KAT6B LARP7 EHF

5.05e-032183031.10.10.10
DomainWHTH_DNA-bd_dom

KAT6B LARP7 EHF

6.74e-03242303IPR011991
DomainPHD

KAT6B RAI1

8.96e-0389302SM00249
DomainZnf_PHD

KAT6B RAI1

9.35e-0391302IPR001965
DomainZF_PHD_2

KAT6B RAI1

1.02e-0295302PS50016
DomainZF_PHD_1

KAT6B RAI1

1.04e-0296302PS01359
DomainSAM

PPFIBP1 EHF

1.06e-0297302IPR001660
Domain-

PPFIBP1 EHF

1.25e-021063021.10.150.50
DomainSAM/pointed

PPFIBP1 EHF

1.51e-02117302IPR013761
PathwaySIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES

ROCK1 CFL1 CFL2

1.81e-0535213M16801
PathwayWP_G13_SIGNALING

ROCK1 CFL1 CFL2

2.32e-0538213M39606
PathwayWP_G13_SIGNALING_PATHWAY

ROCK1 CFL1 CFL2

2.52e-0539213MM15898
PathwaySIG_CHEMOTAXIS

ROCK1 CFL1 CFL2

3.88e-0545213M5193
PathwayREACTOME_RHO_GTPASES_ACTIVATE_ROCKS

ROCK1 CFL1

3.56e-0419212M27493
PathwayKEGG_MEDICUS_REFERENCE_CXCR4_GNB_G_RAC_SIGNALING_PATHWAY

CFL1 CFL2

6.72e-0426212M47561
PathwayKEGG_MEDICUS_PATHOGEN_HIV_GP120_TO_CXCR4_GNB_G_RAC_SIGNALING_PATHWAY

CFL1 CFL2

6.72e-0426212M47562
PathwayKEGG_AXON_GUIDANCE

ROCK1 CFL1 CFL2

8.83e-04129213M5539
PathwayWP_REGULATION_OF_ACTIN_CYTOSKELETON

ROCK1 CFL1 CFL2

1.36e-03150213M39520
PathwayWP_REGULATION_OF_ACTIN_CYTOSKELETON

ROCK1 CFL1 CFL2

1.42e-03152213MM15834
PathwayWP_SMITHMAGENIS_AND_POTOCKILUPSKI_SYNDROME_COPY_NUMBER_VARIATION

ROCK1 CFL2 RAI1

1.61e-03159213M48090
PathwayREACTOME_EPHB_MEDIATED_FORWARD_SIGNALING

ROCK1 CFL1

1.76e-0342212M27308
PathwayPID_RHOA_PATHWAY

ROCK1 CFL1

2.01e-0345212M12
Pubmed

The three mouse actin-depolymerizing factor/cofilins evolved to fulfill cell-type-specific requirements for actin dynamics.

DSTN CFL1 CFL2

5.79e-10330311809832
Pubmed

TIRF microscopy analysis of human Cof1, Cof2, and ADF effects on actin filament severing and turnover.

DSTN CFL1 CFL2

5.79e-10330326996939
Pubmed

ADF/Cofilin-Mediated Actin Turnover Promotes Axon Regeneration in the Adult CNS.

DSTN CFL1 CFL2

2.32e-09430331400829
Pubmed

Filamin-A regulates actin-dependent clustering of HIV receptors.

ROCK1 CFL1 CFL2

3.23e-08830317572668
Pubmed

ADF/cofilin-mediated actin retrograde flow directs neurite formation in the developing brain.

DSTN CFL1 CFL2

6.92e-081030323259946
Pubmed

Severe protein aggregate myopathy in a knockout mouse model points to an essential role of cofilin2 in sarcomeric actin exchange and muscle maintenance.

DSTN CFL1 CFL2

2.62e-071530324598388
Pubmed

Loss of endogenous thymosin β4 accelerates glomerular disease.

DSTN CFL1 CFL2

4.68e-071830327575556
Pubmed

Malignant progressive tumor cell clone exhibits significant up-regulation of cofilin-2 and 27-kDa modified form of cofilin-1 compared to regressive clone.

CFL1 CFL2

7.19e-07230224023293
Pubmed

Determining the differences in actin binding by human ADF and cofilin.

DSTN CFL1

7.19e-07230211812157
Pubmed

Differential expression of up-regulated cofilin-1 and down-regulated cofilin-2 characteristic of pancreatic cancer tissues.

CFL1 CFL2

7.19e-07230221894436
Pubmed

Mapping of human non-muscle type cofilin (CFL1) to chromosome 11q13 and muscle-type cofilin (CFL2) to chromosome 14.

CFL1 CFL2

7.19e-0723028800436
Pubmed

The ADF/cofilin proteins: stimulus-responsive modulators of actin dynamics.

CFL1 CFL2

7.19e-0723028589446
Pubmed

Mapping the ADF/cofilin binding site on monomeric actin by competitive cross-linking and peptide array: evidence for a second binding site on monomeric actin.

DSTN CFL1

7.19e-07230217196218
Pubmed

Solution structure of human cofilin: actin binding, pH sensitivity, and relationship to actin-depolymerizing factor.

DSTN CFL1

7.19e-07230214627701
Pubmed

The ADF/cofilin family: actin-remodeling proteins.

CFL1 CFL2

7.19e-07230212049672
Pubmed

ADF and cofilin-1 collaborate to promote cortical actin flow and the leader bleb-based migration of confined cells.

DSTN CFL1

7.19e-07230234169836
Pubmed

N-cofilin can compensate for the loss of ADF in excitatory synapses.

DSTN CFL1

7.19e-07230222046357
Pubmed

Proteomic profiling identifies an UV-induced activation of cofilin-1 and destrin in human epidermis.

DSTN CFL1

7.19e-07230215816841
Pubmed

Differential involvement of destrin and cofilin-1 in the control of invasive properties of Isreco1 human colon cancer cells.

DSTN CFL1

7.19e-07230217583572
Pubmed

Cofilin hyperactivation in HIV infection and targeting the cofilin pathway using an anti-α4β7 integrin antibody.

CFL1 CFL2

7.19e-07230230662943
Pubmed

Characterization of a novel cofilin isoform that is predominantly expressed in mammalian skeletal muscle.

CFL1 CFL2

7.19e-0723028195165
Pubmed

ADF and Cofilin1 Control Actin Stress Fibers, Nuclear Integrity, and Cell Survival.

DSTN CFL1

7.19e-07230226655907
Pubmed

Actin-depolymerizing factor and cofilin-1 play overlapping roles in promoting rapid F-actin depolymerization in mammalian nonmuscle cells.

DSTN CFL1

2.16e-06330215548599
Pubmed

ADF/cofilin regulates secretory cargo sorting at the TGN via the Ca2+ ATPase SPCA1.

DSTN CFL1

2.16e-06330221571222
Pubmed

Biophysics of actin filament severing by cofilin.

CFL1 CFL2

2.16e-06330223395798
Pubmed

A study of the expression and interaction of Destrin, cofilin, and LIMK in Debakey I type thoracic aortic dissection tissue.

DSTN CFL1

2.16e-06330220873970
Pubmed

Attention-Deficit/Hyperactivity Disorder-like Phenotype in a Mouse Model with Impaired Actin Dynamics.

DSTN CFL1

2.16e-06330224768258
Pubmed

How to engage Cofilin.

CFL1 CFL2

2.16e-06330218808680
Pubmed

ADF/n-cofilin-dependent actin turnover determines platelet formation and sizing.

DSTN CFL1

2.16e-06330220530287
Pubmed

Dephosphorylation of serine 3 regulates nuclear translocation of cofilin.

CFL1 CFL2

2.16e-0633028824278
Pubmed

Actin-Depolymerizing Factor and Cofilin-1 Have Unique and Overlapping Functions in Regulating Intestinal Epithelial Junctions and Mucosal Inflammation.

DSTN CFL1

2.16e-06330226878213
Pubmed

HIV-1 Nef interferes with host cell motility by deregulation of Cofilin.

CFL1 CFL2

2.16e-06330219683683
Pubmed

Actin filament turnover drives leading edge growth during myelin sheath formation in the central nervous system.

DSTN CFL1

2.16e-06330226166299
Pubmed

Prolyl hydroxylase domain (PHD) 2 affects cell migration and F-actin formation via RhoA/rho-associated kinase-dependent cofilin phosphorylation.

ROCK1 CFL2

4.31e-06430220801873
Pubmed

Cofilin weakly interacts with 14-3-3 and therefore can only indirectly participate in regulation of cell motility by small heat shock protein HspB6 (Hsp20).

CFL1 CFL2

4.31e-06430222450169
Pubmed

Expression of cofilin isoforms during development of mouse striated muscles.

CFL1 CFL2

4.31e-06430210813634
Pubmed

Control of growth cone motility and morphology by LIM kinase and Slingshot via phosphorylation and dephosphorylation of cofilin.

CFL1 CFL2

4.31e-06430212684437
Pubmed

Rho-associated coiled-coil kinase (ROCK) protein controls microtubule dynamics in a novel signaling pathway that regulates cell migration.

ROCK1 CFL1

7.18e-06530223093407
Pubmed

N-cofilin is associated with neuronal migration disorders and cell cycle control in the cerebral cortex.

DSTN CFL1

7.18e-06530217875668
Pubmed

Actin depolymerizing factors cofilin1 and destrin are required for ureteric bud branching morphogenesis.

DSTN CFL1

7.18e-06530221060807
Pubmed

Actin at stereocilia tips is regulated by mechanotransduction and ADF/cofilin.

DSTN CFL1

7.18e-06530233400922
Pubmed

Cofilin phosphorylation and actin reorganization activities of testicular protein kinase 2 and its predominant expression in testicular Sertoli cells.

DSTN CFL1

1.08e-05630211418599
Pubmed

Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase.

ROCK1 CFL1

1.08e-05630210436159
Pubmed

Nf1 RasGAP inhibition of LIMK2 mediates a new cross-talk between Ras and Rho pathways.

ROCK1 CFL1

1.08e-05630223082153
Pubmed

Control of actin reorganization by Slingshot, a family of phosphatases that dephosphorylate ADF/cofilin.

DSTN CFL1

1.08e-05630211832213
Pubmed

Rho-kinase-dependent actin turnover and actomyosin disassembly are necessary for mouse spinal neural tube closure.

ROCK1 CFL1

1.08e-05630226040287
Pubmed

Cofilin phosphorylation by LIM-kinase 1 and its role in Rac-mediated actin reorganization.

CFL1 CFL2

1.08e-0563029655398
Pubmed

Wdr1-mediated cell shape dynamics and cortical tension are essential for epidermal planar cell polarity.

DSTN CFL1

1.08e-05630225915128
Pubmed

The actin depolymerizing factor n-cofilin is essential for neural tube morphogenesis and neural crest cell migration.

DSTN CFL1

1.08e-05630215649475
Pubmed

A generic approach for the purification of signaling complexes that specifically interact with the carboxyl-terminal domain of G protein-coupled receptors.

DSTN CFL1 CFL2

1.47e-055530318448421
Pubmed

The actin-binding protein CAP1 represses MRTF-SRF-dependent gene expression in mouse cerebral cortex.

DSTN CFL1

1.51e-05730238713765
Pubmed

Activation of LIM kinases by myotonic dystrophy kinase-related Cdc42-binding kinase alpha.

ROCK1 CFL1

2.01e-05830211340065
Pubmed

HIV envelope-CXCR4 signaling activates cofilin to overcome cortical actin restriction in resting CD4 T cells.

CFL1 CFL2

2.58e-05930218775311
Pubmed

Autotaxin/lysophospholipase D-mediated lysophosphatidic acid signaling is required to form distinctive large lysosomes in the visceral endoderm cells of the mouse yolk sac.

ROCK1 CFL1

2.58e-05930219808661
Pubmed

HERC5 is an IFN-induced HECT-type E3 protein ligase that mediates type I IFN-induced ISGylation of protein targets.

DSTN CFL1

3.94e-051130216815975
Pubmed

N-terminal Slit2 inhibits HIV-1 replication by regulating the actin cytoskeleton.

CFL1 CFL2

3.94e-051130223294842
Pubmed

Cofilin and Vangl2 cooperate in the initiation of planar cell polarity in the mouse embryo.

DSTN CFL1

4.72e-051230223406901
Pubmed

Planar cell polarity genes Celsr1 and Vangl2 are necessary for kidney growth, differentiation, and rostrocaudal patterning.

DSTN CFL1

5.58e-051330227597235
Pubmed

Loss of ARHGEF6 Causes Hair Cell Stereocilia Deficits and Hearing Loss in Mice.

CFL1 CFL2

5.58e-051330230333726
Pubmed

Clarifying the role of G protein signaling in HIV infection: new approaches to an old question.

CFL1 CFL2

8.57e-051630220842205
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

CHST12 BCKDHA DSTN PSTPIP1 PPFIBP1 CFL1 EHF

8.88e-05128430717353931
Pubmed

A cardiomyocyte-specific Wdr1 knockout demonstrates essential functional roles for actin disassembly during myocardial growth and maintenance in mice.

CFL1 CFL2

1.09e-041830224840128
Pubmed

HSPB7 is indispensable for heart development by modulating actin filament assembly.

CFL1 CFL2

1.09e-041830229078393
Pubmed

The tumour suppressor PTEN mediates a negative regulation of the E3 ubiquitin-protein ligase Nedd4.

DSTN CFL1 CFL2

1.17e-0411030318307411
Pubmed

Modifications in the human T cell proteome induced by intracellular HIV-1 Tat protein expression.

CFL1 CFL2

1.64e-042230216526095
Pubmed

Role of the focal adhesion protein TRIM15 in colon cancer development.

ROCK1 CFL1

2.13e-042530225450970
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

QSER1 ATP11B KAT6B DNAH14 ANKAR RAI1 EHF

2.22e-04148930728611215
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

ROCK1 NBEAL1 KIF26B PPFIBP1 TPRN

2.84e-0468930536543142
Pubmed

Secretory pathway calcium ATPase 1 (SPCA1) controls mouse neural tube closure by regulating cytoskeletal dynamics.

ROCK1 CFL1

2.88e-042930230228103
Pubmed

Targeted ubiquitination and degradation of G-protein-coupled receptor kinase 5 by the DDB1-CUL4 ubiquitin ligase complex.

UBTF PPFIBP1 CFL1

3.29e-0415630322952844
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

BCKDHA ARHGEF33 KAT6B TPRN LARP7 RAI1

3.30e-04111630631753913
Pubmed

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.

ROCK1 SOCS6 ATP11B UBTF PPFIBP1

3.46e-0471930535337019
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

TIGD4 ARHGEF33 KIF26B DNAH14 RAI1

3.85e-0473630529676528
Pubmed

CRISPR activation screen identifies BCL-2 proteins and B3GNT2 as drivers of cancer resistance to T cell-mediated cytotoxicity.

DSTN UBTF PPFIBP1 CFL1

4.40e-0441830435338135
Pubmed

Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.

NBEAL1 TPRN ANKAR EHF TAFA2

6.08e-0481430523251661
Pubmed

Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense.

PROM1 CFL1

7.27e-044630219190083
Pubmed

Rewiring of the Human Mitochondrial Interactome during Neuronal Reprogramming Reveals Regulators of the Respirasome and Neurogenesis.

PROM1 BCKDHA DSTN CFL1 CFL2

7.75e-0485930531536960
Pubmed

An atlas of combinatorial transcriptional regulation in mouse and man.

TIGD4 PPARD UBTF RAI1 EHF

8.51e-0487730520211142
InteractionLDHAL6A interactions

DSTN CFL1 CFL2

3.05e-0541303int:LDHAL6A
InteractionCFL2 interactions

DSTN CFL1 CFL2 LARP7

3.10e-05122304int:CFL2
CytobandEnsembl 112 genes in cytogenetic band chr11p13

QSER1 EHF

8.37e-0465302chr11p13
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

BRINP3 CWH43 KIF26B EHF

6.40e-06181304b7c85fbef3c06d5dc32a2a58f8d3dfabf1d79d9f
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

BRINP3 CWH43 KIF26B EHF

7.59e-06189304c9565e962a13a7713056ec3dbb1b67d24f9889c7
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

PROM1 BRINP3 KIF26B CFL1

7.59e-06189304f75cebd4c3e54e297557449ba67ccc8d1a2a14f5
ToppCellILEUM-non-inflamed-(8)_Fibroblast-(8)_Smooth_muscle_cells|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

PROM1 DSTN CFL1 CFL2

8.94e-061973044e0c3ea4f4a04a41532806edf3bccf7845c86fa5
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Mesenchymal|GW19 / Sample Type, Dataset, Time_group, and Cell type.

KIF26B PPFIBP1 CFL2

1.64e-04159303f34f2729a3872fbb2939e76ad35d7e25f71b8f57
ToppCellIIF-Lymphocyte-T_NK-CD4_CTL|IIF / Disease, Lineage and Cell Type

CHST12 DSTN CFL1

1.64e-0415930364e2b57e09bf25b2582f154375bb88cfd02a2521
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Mesenchymal-Unfolded_protein_responsible_cell|GW19 / Sample Type, Dataset, Time_group, and Cell type.

KIF26B PPFIBP1 CFL2

1.64e-04159303929ed98f6c2ad14e8d5af5c6f11a5a3d4b388cf7
ToppCellsevere-HSPC|World / disease stage, cell group and cell class

PROM1 PPFIBP1 DNAH14

1.96e-04169303b0421b73bfdc92f7a2762b4b670b9eae124aa702
ToppCellfacs-Marrow-T_cells-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PROM1 CHST12 DSTN

2.03e-0417130395e87987a2332fa646849fb0de785f1e0b8a07dd
ToppCellfacs-Marrow-T_cells-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PROM1 CHST12 DSTN

2.03e-0417130336657e277aad75c4f157c1726c48e09b5836cf37
ToppCell10x3'2.3-week_14-16-Hematopoietic-HSC/MPP_and_pro-CMP|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

KANK4 PROM1 CHST12

2.07e-04172303f18d9f061df3da96e389616abd5edfc269d3adeb
ToppCellAdult-Epithelial-club_cell-D175|Adult / Lineage, Cell type, age group and donor

PROM1 RAI1 EHF

2.25e-04177303d652b7d84fe6aa38319d8d5adc72c70441bd0088
ToppCell21-Trachea-Epithelial-Submucosal_gland|Trachea / Age, Tissue, Lineage and Cell class

KANK4 PROM1 EHF

2.29e-041783033e406e38eea0d38dc25edecf703c4c89ec6a28e0
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L4-5_RORB_LINC01474|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BRINP3 PPFIBP1 TAFA2

2.29e-04178303f7f88879a05b2b5fa92cf5317b76f7a3064d1358
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BRINP3 DNAH14 TAFA2

2.32e-041793038766a5a066091879f521acfc612abf563ff78808
ToppCellLPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KANK4 EHF TAFA2

2.32e-04179303fd2cbee532e7b44113410dca82aec7db1a7fb69f
ToppCellHSPCs-Neutro_prog.|HSPCs / Lineage and Cell class

PROM1 CHST12 DSTN

2.36e-04180303328192f4678dcdc01c806362b225e770d23498d6
ToppCellLPS_only-Epithelial_alveolar-AT_2-AT2_Progenitor|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KANK4 EHF TAFA2

2.40e-041813030513b9e6673ff7bf8e72ba123ca3794b65d10170
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PPFIBP1 CFL1 TAFA2

2.44e-04182303fa16e194f04250149c82e86551270b244cbc8af4
ToppCellHSPCs-Neutro_prog.|World / Lineage and Cell class

PROM1 CHST12 DSTN

2.44e-04182303f2512354b90f55bf4172c28084bf52cf79e41d8a
ToppCellRA-13._Vascular_Smooth_Muscle|RA / Chamber and Cluster_Paper

ROCK1 DSTN NBEAL1

2.48e-04183303818fd886e0188091310825f9145fa53328f2c979
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

BRINP3 KIF26B CFL1

2.48e-04183303e84539978ab4de42e19186aed00f24bb50cbc21f
ToppCellLPS_only-Epithelial_alveolar-AT_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KANK4 EHF TAFA2

2.48e-04183303e972432dd4d1bd31bb0982f4df3061e5e152658f
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KANK4 EHF TAFA2

2.52e-04184303ab2f06906fc7a9931dfa0864ef506832b07fb93e
ToppCellLPS_only-Epithelial_alveolar-AT_1-AT1-AT2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KANK4 EHF TAFA2

2.56e-0418530368f428e169cfb77de970bdfdeea9b9f16f68d2ba
ToppCelldroplet-Marrow-nan-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PROM1 CHST12 DSTN

2.56e-041853033dcafbd02b65a2befbb6e6288cb2591e721cddb6
ToppCelldroplet-Marrow-BM-30m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PROM1 CHST12 DSTN

2.56e-041853034157cc14b06bb99ee67ac1526622cf546e727efc
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BRINP3 PPFIBP1 TAFA2

2.60e-04186303bdbe290f81106a53c8c30a92fbb385597c62b2ac
ToppCellLPS_only-Epithelial_alveolar|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KANK4 EHF TAFA2

2.60e-04186303e0a2ea4b46af742bc7c9b2072bb85e27d5c92712
ToppCelldroplet-Marrow-nan-18m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHST12 DSTN CFL1

2.60e-041863031bb10a6625c0ada3fe0f0adf7b5899d299d2a9c0
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BRINP3 PPFIBP1 TAFA2

2.64e-04187303f18628ffc7ff7c762b8339ba8822cf0c3157f469
ToppCelldroplet-Bladder-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ROCK1 NBEAL1 EHF

2.64e-04187303663991a8afe652e92363b64bcbd68c14d0307f0e
ToppCelldroplet-Marrow-nan-21m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHST12 DSTN CFL1

2.64e-0418730320b25b0d08550a1e8e997c5ce67d8e34bf7fc398
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PROM1 DSTN PPFIBP1

2.64e-041873039225caf66e06ebe57e90d677122acb6498607f36
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KANK4 EHF TAFA2

2.68e-041883034bdf8d49af0e9da349b16e3f012e1b0eec04cc4f
ToppCelldroplet-Marrow-nan-18m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHST12 DSTN CFL1

2.68e-041883030a874578f5692a896ea3071a17d87cdeb242fb11
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PROM1 PPFIBP1 DNAH14

2.68e-0418830363a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCelldroplet-Marrow-nan-18m-Myeloid-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHST12 DSTN CFL1

2.68e-04188303fa7a612b0a2b35de5f76a0408168dabe5db00773
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

ROCK1 DSTN NBEAL1

2.68e-0418830334e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCellControl-Epithelial_cells|Control / group, cell type (main and fine annotations)

DSTN NBEAL1 DNAH14

2.68e-04188303707ebf76cc6fb600b2f07793cf4ea9482c0de79d
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

PROM1 BRINP3 KIF26B

2.68e-041883033004e961d214919e08c7cd5f10c3de5cf85b35a3
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BRINP3 CWH43 EHF

2.72e-041893033a295c215b5c18e7c673f92b7af5be523421682c
ToppCellCOVID-19_Severe-HSPC|COVID-19_Severe / disease group, cell group and cell class

PROM1 PPFIBP1 DNAH14

2.72e-0418930396015439971e2e5b8d6294ca5a6b873c7774e925
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BRINP3 CWH43 EHF

2.72e-04189303fc88c51ace7d883c01617f3f9b5fab70cc91cc09
ToppCellLA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

ROCK1 DSTN NBEAL1

2.72e-041893036b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CWH43 KIF26B EHF

2.72e-041893038ff3c3232eff9de4b5c9b22ecb82bc509d773f58
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PROM1 PPFIBP1 DNAH14

2.72e-04189303904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PROM1 KIF26B PPFIBP1

2.72e-041893033b48b0d220cc24d5170713d61fa91f5bb6c21841
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

BRINP3 PSTPIP1 KIF26B

2.72e-041893030abc7a4900cc9033bc1be69b770ccc54a6bf41b4
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BRINP3 CWH43 EHF

2.72e-04189303532aaf02b364c5c4f58a2021c7c21d86df3875c9
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BRINP3 PPFIBP1 TAFA2

2.72e-04189303c3df0e3c50af8f1cfb4d790e668bd7f42b276992
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Macroglial-Schwann_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KANK4 CWH43 TAFA2

2.77e-04190303ff3dec5b45c6ea9b5319fb51a0198c6773b7be26
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PROM1 DSTN PPFIBP1

2.77e-04190303b855b8b7d3439023390ca44629c1a99f5d4c6801
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PROM1 DNAH14 EHF

2.77e-041903033fc9e18c7441c0ae8cda65753cc42d0520f4e116
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Macroglial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KANK4 CWH43 TAFA2

2.77e-041903034971857eac9af17d66d673ed2ab7072639f60a10
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_T-CytoT_GZMH+-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

CHST12 DSTN CFL1

2.81e-04191303b2d0ea24970da09209da9d9dda76e30fbfe22917
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PROM1 KIF26B PPFIBP1

2.81e-041913031cb02007adb344f17ef73d58890f91298c7cf5a1
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PROM1 PPFIBP1 DNAH14

2.81e-04191303d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PROM1 NBEAL1 UBTF

2.81e-0419130309db184cb90fe282a14474d7217068c58092c6f8
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-myocytic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PROM1 DSTN CFL2

2.90e-04193303a402e736440684ebe123673b6b0c6fcd8fa057b2
ToppCellnormal-na-Lymphocytic_T-CytoT_GZMH+-female|normal / PBMC cell types (v2) per disease, treatment status, and sex

CHST12 DSTN CFL1

2.90e-041933033184a5f454e3ac5a81f6bacf9bd8f07d9d448fba
ToppCellnormal-na-Lymphocytic_T-CytoT_GZMH+|normal / PBMC cell types (v2) per disease, treatment status, and sex

CHST12 DSTN CFL1

2.90e-04193303123d4d13c8944c32bf4a5d7fdc65e3b65aa568ef
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BRINP3 CWH43 EHF

2.94e-04194303be869e186386d03ebb670971dd24fa656b4b0edf
ToppCelltumor_Lung-T/NK_cells-Exhausted_CD8+_T|tumor_Lung / Location, Cell class and cell subclass

CHST12 PSTPIP1 CFL1

2.94e-041943033fdcfd04174e39491d4f1e6276acc9d11e5a4345
ToppCellIIF-Lymphocyte-T_NK-CD8_TEM|IIF / Disease, Lineage and Cell Type

CHST12 DSTN CFL1

2.94e-04194303f4f7c85963ba52ee7ca2ef5657e60680fe6332fe
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BRINP3 CWH43 EHF

2.94e-041943034d6c9b016e3a0641954a8ea10c97d1cd76fadd9f
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_NK-natural_killer_cell|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

CHST12 DSTN CFL1

2.99e-0419530349a4f58aac168fc1838bd5d2b202135cd794c28b
ToppCelltumor_Lymph_Node_/_Brain-T/NK_cells-Exhausted_CD8+_T|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

CHST12 PSTPIP1 CFL1

2.99e-04195303f2029195d5b655120a9e84074b2583e2d89c0a1d
ToppCellBronchial-10x5prime-Epithelial-Epi_submucosal-gland-SMG_Duct|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

KANK4 PROM1 EHF

2.99e-04195303fc2a1d84b3d013e5cb9e7b9cdd740e4010897d20
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Epithelial-luminal_epithelial_cell_of_mammary_gland|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PROM1 TPRN EHF

2.99e-04195303c87edbb8c92a0541b6de2632ac2f9cef44c7e304
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_NK-natural_killer_cell-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

CHST12 DSTN CFL1

2.99e-0419530372f42f0be53a2a61f61647118b4883e752d998a5
ToppCell3'-Broncho-tracheal-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Fibromyocytes|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BRINP3 DSTN CFL2

3.03e-041963035159d8625d80c20eb28157b2603c8bde9d377a35
ToppCell3'-Broncho-tracheal-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Fibromyocytes-Fibromyocytes_L.2.3.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BRINP3 DSTN CFL2

3.03e-041963036b5b7dbcb2cce8a736e44145a01290905876a5e9
ToppCelldroplet-Mammary_Gland-nan-3m-Epithelial-luminal_epithelial_cell_of_mammary_gland|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PROM1 TPRN EHF

3.03e-041963039554ac6eb5f381bcde3ba40c32aa3fc340974540
ToppCellBronchial_Brush-Epithelial|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

PROM1 DSTN EHF

3.08e-04197303272c7f4e582ef57564450540242b0db766b78328
ToppCellLPS_only-Epithelial_alveolar-AT_2-AT2|LPS_only / Treatment groups by lineage, cell group, cell type

KANK4 EHF TAFA2

3.12e-041983036b6572deeca98ccb015f2aa3c5ce27de44445f74
ToppCellremission-NK|World / disease stage, cell group and cell class

CHST12 DSTN CFL1

3.12e-04198303383ed78164ad37826100d3de6c3cc14f62e01813
ToppCell(200)_CD56+_NK_cell|World / immune cells in Peripheral Blood (logTPM normalization)

CHST12 DSTN CFL1

3.12e-04198303459e841a01a900808707140297c89c1d6a79024f
ToppCellLPS_only-Epithelial_alveolar-AT_2|LPS_only / Treatment groups by lineage, cell group, cell type

KANK4 EHF TAFA2

3.12e-04198303d087e738d69ca9853553fde46d4e7a8906439d32
ToppCellMultiple_Sclerosis|World / Disease, Lineage and Cell Type

CHST12 NBEAL1 CFL1

3.12e-0419830346728bb03f4b0d30ae9b62d984a6c2d00cfd370a
ToppCellcellseq-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

BRINP3 DSTN CFL2

3.12e-04198303e9f434bfd072e590fe44d518057ee5aa653038f3
ToppCell(2)_NK/T-(20)_NK_cell|(2)_NK/T / immune cells in Peripheral Blood (logTPM normalization)

CHST12 DSTN CFL1

3.12e-041983032e4851e49457940e841660c5d781499ffb4a2bf1
ToppCell(2)_NK/T-(200)_CD56+_NK_cell|(2)_NK/T / immune cells in Peripheral Blood (logTPM normalization)

CHST12 DSTN CFL1

3.12e-0419830303477a6356a3c08c6e723165c0aac3464ef01667
ToppCell(20)_NK_cell|World / immune cells in Peripheral Blood (logTPM normalization)

CHST12 DSTN CFL1

3.12e-04198303178b885e56e734a4408032ea79c68163333de9b6
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Goblet|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PROM1 KIF26B EHF

3.12e-04198303af07a970afaa435c6433bb5c1cbff4c67af350c7
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal-6|World / Primary Cells by Cluster

DSTN PPFIBP1 CFL1

3.17e-041993031b1bccf4293f11048709d15a3c892c0edf3da3d2
ToppCellPBMC-Convalescent-Lymphocyte-T/NK-NK_cell-NK|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CHST12 DSTN CFL1

3.17e-04199303fd3706f256e33cf348774bea0ba0df6d41fd96e3
ToppCellNS-critical-d_07-13-Epithelial|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PROM1 DSTN EHF

3.17e-04199303b88a81cd2a89f4d27100c96ae4324dcee68daf83
ToppCellPBMC-Convalescent-Lymphocyte-T/NK-NK_cell-NK-|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CHST12 DSTN CFL1

3.17e-04199303252f0084fa17770f4c34e21066519d7f7cad75d9
ToppCellPBMC-Convalescent-Lymphocyte-T/NK-NK_cell-NK|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)

CHST12 DSTN CFL1

3.17e-04199303899642ff6bb6c1612f14a9a049b4344ae694752a
ToppCellPBMC-Convalescent-Lymphocyte-T/NK-NK_cell-NK-|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CHST12 DSTN CFL1

3.17e-04199303e981b159841222a6838effff1059c683c20ecf5b
ToppCellcritical-Epithelial|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

PROM1 DSTN EHF

3.17e-04199303bbb44e2a52f102a6d891ead6c06d6c07221abd33
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-CD8_cytotoxic|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CHST12 PSTPIP1 CFL1

3.17e-041993038f2b57cf2f932f20ea029132d8bda01aac774571
ToppCellPBMC-Convalescent-Lymphocyte-T/NK-NK_cell|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CHST12 DSTN CFL1

3.17e-041993038cdd5aa30a8112b77f5d02b40c45b63f541e1476
ToppCellCOVID-19_Convalescent-Lymphoid_T/NK-NK|COVID-19_Convalescent / Disease group, lineage and cell class

CHST12 DSTN CFL1

3.17e-041993039809d996a2c3f5384707646a3929e1d6b85dcdc2
ToppCellPBMC-Convalescent-Lymphocyte-T/NK-NK_cell|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CHST12 DSTN CFL1

3.17e-04199303a2ac6af5e8e13e7edd3302ebdb175a3902bfb2bc
ToppCellCOVID-19_Mild-CD4+_CTL|COVID-19_Mild / Disease condition and Cell class

CHST12 DSTN CFL1

3.17e-04199303a6b408fa84a47ca8208e48938026a980ccd3ea25
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal|World / Primary Cells by Cluster

DSTN PPFIBP1 CFL1

3.17e-041993034bee94c116c0da5eba951cb4cea7cc9dcdd6e30f
ToppCellremission-NK|remission / disease stage, cell group and cell class

CHST12 DSTN CFL1

3.17e-0419930331ed2a314e8f70980ea0686242446d66929288e9
ToppCell15-Trachea-Epithelial|Trachea / Age, Tissue, Lineage and Cell class

PROM1 DSTN EHF

3.17e-04199303e0099aa95cf3ec08d7688cc97f4b917fce65a7a3
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

BRINP3 SOCS6 KAT6B UBTF

6.29e-051653045625_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

BRINP3 SOCS6 KAT6B UBTF

6.59e-051673043979_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

BRINP3 SOCS6 KAT6B UBTF

6.75e-051683043395_DN
DrugTrichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A

BRINP3 SOCS6 KAT6B UBTF

6.91e-051693045231_DN
Drugtrichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A

BRINP3 SOCS6 KAT6B UBTF

7.07e-051703047043_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

BRINP3 SOCS6 KAT6B UBTF

7.07e-051703045260_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A

SOCS6 KAT6B UBTF LARP7

7.07e-051703043791_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

BRINP3 SOCS6 KAT6B UBTF

7.07e-051703044153_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

BRINP3 SOCS6 KAT6B UBTF

7.23e-051713045441_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

BRINP3 SOCS6 KAT6B UBTF

7.39e-051723044112_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

BRINP3 SOCS6 KAT6B UBTF

7.56e-051733045336_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

BRINP3 QSER1 KAT6B UBTF

7.56e-051733042881_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A

SOCS6 KAT6B UBTF LARP7

7.73e-051743043993_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

BRINP3 SOCS6 KAT6B UBTF

7.73e-051743043462_DN
Drugtrichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A

BRINP3 SOCS6 KAT6B UBTF

7.73e-051743045945_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

BRINP3 SOCS6 KAT6B UBTF

7.73e-051743045693_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A

SOCS6 KAT6B UBTF LARP7

7.73e-051743045065_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A

SOCS6 KAT6B UBTF LARP7

7.91e-051753044072_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A

SOCS6 KAT6B UBTF LARP7

7.91e-051753043787_DN
DrugRifabutin [72559-06-9]; Down 200; 4.8uM; MCF7; HT_HG-U133A

BRINP3 QSER1 KAT6B UBTF

7.91e-051753043873_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

BRINP3 SOCS6 KAT6B UBTF

8.08e-051763046784_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

BRINP3 SOCS6 KAT6B UBTF

8.26e-051773043227_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

BRINP3 SOCS6 KAT6B UBTF

8.26e-051773043177_DN
DrugTrichostatin A, Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A

SOCS6 KAT6B UBTF LARP7

8.44e-051783044436_DN
DrugSAHA; Down 200; 10uM; PC3; HT_HG-U133A

SOCS6 KAT6B UBTF LARP7

8.44e-051783044444_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A

SOCS6 KAT6B UBTF LARP7

8.82e-051803043688_DN
DrugC04424

BCKDHA KAT6B

9.16e-0511302CID011953835
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

BRINP3 SOCS6 KAT6B UBTF

9.40e-051833044770_DN
Drugtrichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A

SOCS6 KAT6B UBTF LARP7

1.00e-041863046874_DN
DrugAzacytidine-5 [320-67-2]; Down 200; 16.4uM; MCF7; HT_HG-U133A

CHST12 BRINP3 KAT6B UBTF

1.09e-041903044128_DN
DrugC05118

BCKDHA KAT6B

1.10e-0412302CID000440565
DrugC05119

BCKDHA KAT6B

1.10e-0412302CID000440566
DrugNomifensine maleate [32795-47-4]; Down 200; 11.2uM; PC3; HT_HG-U133A

CWH43 UBTF PPFIBP1 EHF

1.27e-041983042062_DN
DrugSB 202190; Down 200; 1uM; PC3; HT_HG-U133A

QSER1 SOCS6 ATP11B PPFIBP1

1.30e-041993046882_DN
DrugAS-6

PPARD ATP11B

2.53e-0418302CID006438999
Diseasenemaline myopathy 7 (implicated_via_orthology)

DSTN CFL1

9.99e-072302DOID:0110934 (implicated_via_orthology)
Diseasebody weight

SLC44A2 BRINP3 CWH43 KAT6B NBEAL1 DNAH14 TAFA2

2.19e-041261307EFO_0004338
DiseaseAnxiety Disorders

RAI1 TAFA2

9.21e-0444302C0003469
DiseaseAnxiety neurosis (finding)

RAI1 TAFA2

9.21e-0444302C1279420
DiseaseAnxiety States, Neurotic

RAI1 TAFA2

9.21e-0444302C0376280
Diseaseosteoarthritis

SLC44A2 KIF26B CFL1

1.47e-03222303MONDO_0005178
Diseasenon-lobar intracerebral hemorrhage

NBEAL1 DNAH14

1.88e-0363302EFO_0010178
Diseasecortical surface area measurement

QSER1 PSTPIP1 NBEAL1 KIF26B UBTF PPFIBP1

2.05e-031345306EFO_0010736
Diseasecortical thickness

QSER1 NBEAL1 UBTF PPFIBP1 CFL1

4.92e-031113305EFO_0004840

Protein segments in the cluster

PeptideGeneStartEntry
KKTSDSKYPMKRITK

C2orf16

1281

Q68DN1
KRMLLTLKSNKYKSS

BRINP3

531

Q76B58
LKSKMIYASSKDAIK

CFL1

111

P23528
KKSSMAKLYKGLASQ

ARHGEF33

456

A8MVX0
LKSKMIYASSKDAIK

DSTN

111

P60981
TMTTLYIQQLKSKKK

NBEAL1

121

Q6ZS30
RSLKGKLMNSKKLSS

RAI1

1406

Q7Z5J4
MNGKAYNKKTLRTSK

QSER1

1636

Q2KHR3
KYMKSKNILLRHSKK

KAT6B

756

Q8WYB5
LLSLKKKMKVPYLSS

ANKAR

326

Q7Z5J8
VQKSKLSLYKKAMES

PSTPIP1

126

O43586
RLQYEKKLKSTKSLM

PPFIBP1

221

Q86W92
SRVLRMKKKKTKYTS

KIF26B

796

Q2KJY2
LKSKMIYASSKDAIK

CFL2

111

Q9Y281
YLALQKASMASLKKT

LARP7

391

Q4G0J3
KKKNNSSMTYEKLSR

EHF

251

Q9NZC4
LLKFSQLKSSMKLSK

DNAH14

811

Q0VDD8
SPSTSLKSIMKKKDY

KANK4

636

Q5T7N3
YFMSSTLKKLLNKTN

SLC44A2

686

Q8IWA5
KVLKLYKSMTLLNTM

BCKDHA

101

P12694
SSKVLFRKSEKYMKL

CWH43

381

Q9H720
MSKRYLQKATKGKLL

TAFA2

1

Q8N3H0
YLKNFNMTKKKARSI

PPARD

186

Q03181
YLSGKLFNKSKMKLT

PROM1

541

O43490
LSRHLMKVKLKKYTK

CHST12

226

Q9NRB3
TKMALNYKSKSQKRS

ATP11B

266

Q9Y2G3
YGIKKNSLSSIMKNK

TIGD4

46

Q8IY51
KSTRKVYAMKLLSKF

ROCK1

96

Q13464
SSRKKMKISFNDKSL

TPRN

571

Q4KMQ1
KEYISNKRKSMTKLR

UBTF

646

P17480
MKKISLKTLRKSFNL

SOCS6

1

O14544