Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	vesicle cargo loading	CTAGE9 CTAGE8 CTAGE15 CTAGE6 CTAGE4	4.76e-08	36	57	5	GO:0035459
GeneOntologyCellularComponent	endoplasmic reticulum exit site	CTAGE9 CTAGE8 CTAGE15 CTAGE6 CTAGE4	9.06e-08	42	56	5	GO:0070971
Domain	WW	ITCH TCERG1 PLEKHA7	2.86e-04	47	51	3	PF00397
Domain	WW	ITCH TCERG1 PLEKHA7	3.04e-04	48	51	3	SM00456
Domain	WW_DOMAIN_2	ITCH TCERG1 PLEKHA7	3.64e-04	51	51	3	PS50020
Domain	WW_DOMAIN_1	ITCH TCERG1 PLEKHA7	3.64e-04	51	51	3	PS01159
Domain	WW_dom	ITCH TCERG1 PLEKHA7	3.86e-04	52	51	3	IPR001202
Domain	EGF_CA	THBS4 LTBP4 NOTCH3	1.67e-03	86	51	3	PF07645
Domain	EGF_Ca-bd_CS	THBS4 LTBP4 NOTCH3	2.36e-03	97	51	3	IPR018097
Domain	AT_hook	PRR12 SRCAP	2.46e-03	27	51	2	SM00384
Domain	AT_hook_DNA-bd_motif	PRR12 SRCAP	2.46e-03	27	51	2	IPR017956
Domain	EGF_CA	THBS4 LTBP4 NOTCH3	2.50e-03	99	51	3	PS01187
Domain	SH3	SH3PXD2B CASKIN2 NCKIPSD RUSC1	2.84e-03	216	51	4	SM00326
Domain	SH3	SH3PXD2B CASKIN2 NCKIPSD RUSC1	2.84e-03	216	51	4	PS50002
Domain	SH3_domain	SH3PXD2B CASKIN2 NCKIPSD RUSC1	3.04e-03	220	51	4	IPR001452
Domain	RRM_dom	SETD1A SF3B4 SYNJ2 RBM42	3.40e-03	227	51	4	IPR000504
Domain	RRM	SETD1A SF3B4 SYNJ2 RBM42	3.56e-03	230	51	4	PS50102
Domain	-	SETD1A SF3B4 SYNJ2 RBM42	4.39e-03	244	51	4	3.30.70.330
Domain	EGF_CA	THBS4 LTBP4 NOTCH3	4.51e-03	122	51	3	SM00179
Domain	EGF-like_Ca-bd_dom	THBS4 LTBP4 NOTCH3	4.72e-03	124	51	3	IPR001881
Domain	RA_dom	RIN3 PLEKHH3	5.34e-03	40	51	2	IPR000159
Domain	Nucleotide-bd_a/b_plait	SETD1A SF3B4 SYNJ2 RBM42	5.34e-03	258	51	4	IPR012677
Domain	-	SH3PXD2B ZCCHC2	8.56e-03	51	51	2	3.30.1520.10
Domain	Growth_fac_rcpt_	THBS4 LTBP4 NOTCH3	8.88e-03	156	51	3	IPR009030
Domain	Phox	SH3PXD2B ZCCHC2	8.88e-03	52	51	2	IPR001683
Domain	SH3_1	SH3PXD2B NCKIPSD RUSC1	1.02e-02	164	51	3	PF00018
Pubmed	Proteins recruited by SH3 domains of Ruk/CIN85 adaptor identified by LC-MS/MS.	SH3PXD2B POM121 WIPF1 SYNJ2 CASKIN2 PRRC2A	2.23e-08	108	56	6	19531213
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	SH3PXD2B SF3B4 ITCH LATS1 TCERG1 SYNJ2 CASKIN2 NCKIPSD PLEKHA7 VIRMA ANKS1A	1.08e-07	861	56	11	36931259
Pubmed	The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.	PRR12 SF3B4 TPRN FBRS RBM42 UBN2	1.71e-07	152	56	6	38360978
Pubmed	Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.	RIN3 SF3B4 WIPF1 SYNJ2 NCKIPSD FOXH1 NOTCH3	9.91e-07	329	56	7	17474147
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	VWA5B2 CCDC71L PRR12 SETD1A SH3PXD2B RIN3 FBRS NLGN2 SRCAP LTBP4 PLEKHH3	1.27e-06	1105	56	11	35748872
Pubmed	Whole genome sequencing resource identifies 18 new candidate genes for autism spectrum disorder.	LMTK3 SRCAP UBN2	1.42e-06	14	56	3	28263302
Pubmed	Negative regulation of the Hippo pathway by E3 ubiquitin ligase ITCH is sufficient to promote tumorigenicity.	ITCH LATS1	2.55e-06	2	56	2	21212414
Pubmed	Up-regulation of ITCH is associated with down-regulation of LATS1 during tumorigenesis and progression of cervical squamous cell carcinoma.	ITCH LATS1	2.55e-06	2	56	2	25618271
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	SETD1A SH3PXD2B LATS1 TCERG1 SRCAP UBN2 PRRC2A WDR44	2.68e-06	549	56	8	38280479
Pubmed	WW domains provide a platform for the assembly of multiprotein networks.	SF3B4 ITCH WIPF1 TCERG1 VIRMA	5.08e-06	154	56	5	16055720
Pubmed	Myofibrillogenesis Regulator-1 Regulates the Ubiquitin Lysosomal Pathway of Notch3 Intracellular Domain Through E3 Ubiquitin-Protein Ligase Itchy Homolog in the Metastasis of Non-Small Cell Lung Cancer.	ITCH NOTCH3	7.63e-06	3	56	2	38342606
Pubmed	Itch E3 ubiquitin ligase regulates large tumor suppressor 1 stability [corrected].	ITCH LATS1	7.63e-06	3	56	2	21383157
Pubmed	Hepatitis C virus NS3 protein can activate the Notch-signaling pathway through binding to a transcription factor, SRCAP.	SRCAP NOTCH3	1.52e-05	4	56	2	21673954
Pubmed	Amot130 adapts atrophin-1 interacting protein 4 to inhibit yes-associated protein signaling and cell growth.	ITCH LATS1	1.52e-05	4	56	2	23564455
Pubmed	Mea6 controls VLDL transport through the coordinated regulation of COPII assembly.	CTAGE9 CTAGE8	1.52e-05	4	56	2	27311593
Pubmed	MEA6 Deficiency Impairs Cerebellar Development and Motor Performance by Tethering Protein Trafficking.	CTAGE9 CTAGE8	1.52e-05	4	56	2	31244610
Pubmed	Reduced cholesterol and triglycerides in mice with a mutation in Mia2, a liver protein that localizes to ER exit sites.	CTAGE9 CTAGE8	1.52e-05	4	56	2	21807889
Pubmed	Deletion of Mea6 in Cerebellar Granule Cells Impairs Synaptic Development and Motor Performance.	CTAGE9 CTAGE8	1.52e-05	4	56	2	33718348
Pubmed	Specific expression and regulation of the new melanoma inhibitory activity-related gene MIA2 in hepatocytes.	CTAGE9 CTAGE8	1.52e-05	4	56	2	12586826
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	SH3PXD2B ITCH PRR36 NLGN2 LMTK3 UBN2 VIRMA PRRC2A ANKS1A	2.17e-05	963	56	9	28671696
Pubmed	cTAGE: a cutaneous T cell lymphoma associated antigen family with tumor-specific splicing.	CTAGE9 CTAGE4	2.54e-05	5	56	2	12839582
Pubmed	Deubiquitinase YOD1 potentiates YAP/TAZ activities through enhancing ITCH stability.	ITCH LATS1	2.54e-05	5	56	2	28416659
Pubmed	Specific phosphopeptide enrichment with immobilized titanium ion affinity chromatography adsorbent for phosphoproteome analysis.	CTAGE9 CTAGE8	2.54e-05	5	56	2	18630941
Pubmed	Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry.	CTAGE9 CTAGE8	2.54e-05	5	56	2	19131326
Pubmed	Characterization and expression pattern of the novel MIA homolog TANGO.	CTAGE9 CTAGE8	2.54e-05	5	56	2	15183315
Pubmed	Mea6/cTAGE5 cooperates with TRAPPC12 to regulate PTN secretion and white matter development.	CTAGE9 CTAGE8	2.54e-05	5	56	2	38439956
Pubmed	A tissue-specific atlas of mouse protein phosphorylation and expression.	CTAGE9 CTAGE8	2.54e-05	5	56	2	21183079
Pubmed	Intersectin (ITSN) family of scaffolds function as molecular hubs in protein interaction networks.	WIPF1 SYNJ2 FASLG LTBP4	3.18e-05	111	56	4	22558309
Pubmed	Serum deprivation inhibits the transcriptional co-activator YAP and cell growth via phosphorylation of the 130-kDa isoform of Angiomotin by the LATS1/2 protein kinases.	ITCH LATS1	3.80e-05	6	56	2	24101513
Pubmed	cTAGE5 deletion in pancreatic β cells impairs proinsulin trafficking and insulin biogenesis in mice.	CTAGE9 CTAGE8	5.32e-05	7	56	2	29133483
Pubmed	Proteasomal down-regulation of the proapoptotic MST2 pathway contributes to BRAF inhibitor resistance in melanoma.	ITCH LATS1	5.32e-05	7	56	2	36038253
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	POM121 TCERG1 CASKIN2 PLEKHA7 ANKS1A	6.64e-05	263	56	5	34702444
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	SETD1A LATS1 POM121 LMTK3 NYAP1 PLEKHA7	6.64e-05	430	56	6	35044719
Pubmed	Identification of SH3 domain interaction partners of human FasL (CD178) by phage display screening.	SH3PXD2B NCKIPSD FASLG	7.34e-05	50	56	3	19807924
Pubmed	Misexpression of MIA disrupts lung morphogenesis and causes neonatal death.	CTAGE9 CTAGE8	9.10e-05	9	56	2	18342301
Pubmed	A human MAP kinase interactome.	LATS1 POM121 WIPF1 TCERG1 SYNJ2 WDR44	1.30e-04	486	56	6	20936779
Pubmed	NEDD4 E3 ligase inhibits the activity of the Hippo pathway by targeting LATS1 for degradation.	ITCH LATS1	1.66e-04	12	56	2	24107629
Pubmed	Ultrastructural cartilage abnormalities in MIA/CD-RAP-deficient mice.	CTAGE9 CTAGE8	1.96e-04	13	56	2	11839810
Pubmed	The arginine methyltransferase CARM1 regulates the coupling of transcription and mRNA processing.	SF3B4 TCERG1	1.96e-04	13	56	2	17218272
Pubmed	An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.	PRR12 SF3B4 PLEKHA7 NOTCH3	2.07e-04	180	56	4	35198878
Pubmed	cTAGE5/MEA6 plays a critical role in neuronal cellular components trafficking and brain development.	CTAGE9 CTAGE8	2.64e-04	15	56	2	30224460
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	TCERG1 TPRN FBRS ZCCHC2 SRCAP UBN2	3.61e-04	588	56	6	38580884
Pubmed	Notch signaling is a novel regulator of visceral smooth muscle cell differentiation in the murine ureter.	THBS4 NYAP1 NOTCH3	3.68e-04	86	56	3	35103284
Pubmed	A Non-catalytic Function of SETD1A Regulates Cyclin K and the DNA Damage Response.	SETD1A TCERG1	3.83e-04	18	56	2	29474905
Pubmed	The contribution of de novo coding mutations to autism spectrum disorder.	SRCAP UBN2	3.83e-04	18	56	2	25363768
Pubmed	A broadly applicable high-throughput screening strategy identifies new regulators of Dlg4 (Psd-95) alternative splicing.	SF3B4 RBM42	4.75e-04	20	56	2	23636947
Pubmed	A novel common variant in DCST2 is associated with length in early life and height in adulthood.	SF3B4 ZBTB7B	4.75e-04	20	56	2	25281659
Pubmed	Notch signaling maintains Leydig progenitor cells in the mouse testis.	ARX NOTCH3	5.24e-04	21	56	2	18927153
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	PRR12 TCERG1 ATXN7 RBM42 ZBTB7B UBN2 PLEKHA7 VIRMA PRRC2A	6.04e-04	1497	56	9	31527615
Pubmed	Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer.	ITCH SYNJ2 ANKS1A	6.06e-04	102	56	3	15778465
Pubmed	Selected reaction monitoring mass spectrometry reveals the dynamics of signaling through the GRB2 adaptor.	SH3PXD2B WIPF1 WDR44	6.24e-04	103	56	3	21706016
Pubmed	Sertoli Cell Wt1 Regulates Peritubular Myoid Cell and Fetal Leydig Cell Differentiation during Fetal Testis Development.	ARX NOTCH3	6.30e-04	23	56	2	28036337
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	SETD1A SYNJ2 SRCAP	6.42e-04	104	56	3	9205841
Pubmed	Identification of multi-SH3 domain-containing protein interactome in pancreatic cancer: a yeast two-hybrid approach.	SF3B4 NCKIPSD LTBP4	6.78e-04	106	56	3	18654987
Pubmed	The WW domain-containing proteins interact with the early spliceosome and participate in pre-mRNA splicing in vivo.	SF3B4 TCERG1	7.46e-04	25	56	2	15456888
Pubmed	Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex.	SF3B4 TCERG1	7.46e-04	25	56	2	9731529
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	PRR12 SF3B4 TCERG1 RBM42 TIGD5 SRCAP ZBTB7B UBN2	1.04e-03	1294	56	8	30804502
Pubmed	TBX1 is required for normal stria vascularis and semicircular canal development.	THBS4 NOTCH3	1.15e-03	31	56	2	31550482
Pubmed	Identification of interaction partners for individual SH3 domains of Fas ligand associated members of the PCH protein family in T lymphocytes.	WIPF1 FASLG	1.15e-03	31	56	2	19041431
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	PRR12 POM121 NLGN2 ZCCHC2 UBN2	1.18e-03	493	56	5	15368895
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	LATS1 ATXN7 VIRMA PRRC2A WDR44 ANKS1A	1.50e-03	774	56	6	15302935
Pubmed	Interferon gamma receptor 2 gene variants are associated with liver fibrosis in patients with chronic hepatitis C infection.	MMP15 LTBP4	1.55e-03	36	56	2	20587546
Pubmed	STRAP regulates alternative splicing fidelity during lineage commitment of mouse embryonic stem cells.	CTAGE9 CTAGE8	1.55e-03	36	56	2	33230114
Interaction	NCK2 interactions	DDR1 SH3PXD2B SF3B4 WIPF1 CASKIN2 NCKIPSD PHETA1 ZBTB7B FASLG PRRC2A	1.68e-09	262	54	10	int:NCK2
Interaction	ITSN2 interactions	RIN3 WIPF1 SYNJ2 NCKIPSD LMTK3 FASLG LTBP4 VIRMA	5.18e-09	147	54	8	int:ITSN2
Interaction	CTAGE1 interactions	CTAGE8 CTAGE15 CTAGE6 CTAGE4	9.55e-09	10	54	4	int:CTAGE1
Interaction	SH3KBP1 interactions	SH3PXD2B RIN3 POM121 WIPF1 SYNJ2 CASKIN2 ZBTB7B VIRMA PRRC2A ANKS1A	9.83e-09	315	54	10	int:SH3KBP1
Interaction	GRB2 interactions	SH3PXD2B RIN3 SF3B4 ITCH WIPF1 TCERG1 SYNJ2 NCKIPSD PHETA1 ZBTB7B FASLG PLEKHA7 PRRC2A WDR44	1.75e-08	806	54	14	int:GRB2
Interaction	PRMT2 interactions	SETD1A POM121 TIGD5 FASLG PRRC2A PLEKHH3	1.56e-07	91	54	6	int:PRMT2
Interaction	P4HA3 interactions	CASKIN2 FBRS RUSC1 TIGD5 SRCAP ZBTB7B	5.64e-07	113	54	6	int:P4HA3
Interaction	SORBS3 interactions	RIN3 NCKIPSD PHETA1 ZBTB7B FASLG NOTCH3 ANKS1A	1.09e-06	202	54	7	int:SORBS3
Interaction	SH3PXD2A interactions	SH3PXD2B RIN3 PRSS12 FASLG PLEKHA7 VIRMA	1.17e-06	128	54	6	int:SH3PXD2A
Interaction	MANSC1 interactions	DDR1 POM121 NOTCH3 PLEKHH3 WDR44	8.59e-06	104	54	5	int:MANSC1
Interaction	NELL2 interactions	ATXN7 ARX LTBP4 VIRMA	1.22e-05	53	54	4	int:NELL2
Interaction	PTCH2 interactions	VIRMA PLEKHH3 WDR44	2.01e-05	20	54	3	int:PTCH2
Interaction	SNX33 interactions	RIN3 NCKIPSD FASLG VIRMA	2.60e-05	64	54	4	int:SNX33
Interaction	ZCCHC2 interactions	ZCCHC2 VIRMA PRRC2A	3.10e-05	23	54	3	int:ZCCHC2
Interaction	EYA4 interactions	PRR12 SF3B4 TPRN FBRS RBM42 UBN2	4.60e-05	243	54	6	int:EYA4
Interaction	NCK1 interactions	SH3PXD2B WIPF1 SYNJ2 CASKIN2 NCKIPSD FASLG	4.70e-05	244	54	6	int:NCK1
Interaction	SHANK3 interactions	SH3PXD2B NCKIPSD NLGN2 ZCCHC2 LMTK3 LTBP4 VIRMA NOTCH3	4.90e-05	496	54	8	int:SHANK3
Interaction	SNX18 interactions	RIN3 ITCH ZBTB7B FASLG	6.57e-05	81	54	4	int:SNX18
Interaction	TMED7 interactions	POM121 MMP15 VIRMA PLEKHH3	7.58e-05	84	54	4	int:TMED7
Interaction	NEDD9 interactions	ITCH VIRMA NOTCH3 ANKS1A	7.94e-05	85	54	4	int:NEDD9
Interaction	ABI2 interactions	WIPF1 CASKIN2 NCKIPSD RUSC1 PHETA1 ANKS1A	1.13e-04	286	54	6	int:ABI2
Interaction	PACSIN2 interactions	RIN3 WIPF1 NCKIPSD FASLG ANKS1A	1.36e-04	185	54	5	int:PACSIN2
Interaction	HSPA1B interactions	SETD1A DDR1 RIN3 TCERG1 LMTK3 VIRMA	1.49e-04	301	54	6	int:HSPA1B
Interaction	GRAP2 interactions	RIN3 ITCH ZBTB7B FASLG	1.74e-04	104	54	4	int:GRAP2
Interaction	ARHGAP10 interactions	SETD1A VIRMA ANKS1A	1.80e-04	41	54	3	int:ARHGAP10
Interaction	JAG1 interactions	ITCH VIRMA NOTCH3	1.80e-04	41	54	3	int:JAG1
Interaction	JCAD interactions	LATS1 NCKIPSD VIRMA	1.94e-04	42	54	3	int:JCAD
Interaction	WBP4 interactions	SF3B4 WIPF1 TCERG1 RBM42	2.08e-04	109	54	4	int:WBP4
Interaction	MIA2 interactions	CTAGE8 CTAGE15 CTAGE6 CTAGE4	2.39e-04	113	54	4	int:MIA2
Interaction	TBR1 interactions	PRR12 LATS1 FBRS VIRMA	2.39e-04	113	54	4	int:TBR1
Interaction	DTX2 interactions	PRR12 SF3B4 RUSC1 ZBTB7B PLEKHA7 NOTCH3	2.45e-04	330	54	6	int:DTX2
Interaction	FLRT1 interactions	DDR1 VIRMA PLEKHH3	2.54e-04	46	54	3	int:FLRT1
Interaction	USP54 interactions	LATS1 NCKIPSD VIRMA PRRC2A ANKS1A	2.56e-04	212	54	5	int:USP54
Interaction	CEP76 interactions	LATS1 POM121 TCERG1 TTLL10 VIRMA	2.91e-04	218	54	5	int:CEP76
Interaction	UFSP1 interactions	RUSC1 FOXH1 VIRMA	3.07e-04	49	54	3	int:UFSP1
Cytoband	7q35	CTAGE8 CTAGE15 CTAGE6 CTAGE4	6.94e-07	55	57	4	7q35
Cytoband	Ensembl 112 genes in cytogenetic band chr7q35	CTAGE8 CTAGE15 CTAGE6 CTAGE4	1.45e-06	66	57	4	chr7q35
Cytoband	16p11.2	SETD1A FBRS SRCAP	1.76e-03	191	57	3	16p11.2
GeneFamily	CTAGE family	CTAGE9 CTAGE8 CTAGE15 CTAGE6 CTAGE4	5.98e-11	15	35	5	907
GeneFamily	Receptor Tyrosine Kinases\|CD molecules	DDR1 LMTK3	2.71e-03	40	35	2	321
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	PHETA1 PLEKHA7 PLEKHH3	7.30e-03	206	35	3	682
GeneFamily	RNA binding motif containing	SETD1A SF3B4 RBM42	8.00e-03	213	35	3	725
GeneFamily	Ankyrin repeat domain containing	CASKIN2 NOTCH3 ANKS1A	1.13e-02	242	35	3	403
GeneFamily	Sterile alpha motif domain containing	CASKIN2 ANKS1A	1.26e-02	88	35	2	760
Coexpression	GSE39820_CTRL_VS_TGFBETA1_IL6_IL23A_CD4_TCELL_UP	TMEM62 LATS1 POM121 WIPF1 TCERG1 ZCCHC2 WDR44	2.21e-07	199	56	7	M5607
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-enteroendocrine_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWA5B2 PRSS12 TMEM198 ARX NLGN2	3.72e-06	183	57	5	d26c7b79895de28961b8d68351f28d4bb531c75c
ToppCell	(00)_Basal-(0)_Reference\|(00)_Basal / shred by cell type by condition	DDR1 CTAGE15 CTAGE6 ZBTB7B PRRC2A	5.19e-06	196	57	5	ba03530a20d7b29902721fd50df8d860557ddefa
ToppCell	(05)_Secretory-(0)_Reference\|(05)_Secretory / shred by cell type by condition	DDR1 RBM42 CTAGE15 CTAGE6 PRRC2A	5.19e-06	196	57	5	7cb79cf122852c971f2d6e8d1e2b26eade891e83
Drug	6,7-dimethoxy-2-(pyrrolidin-1-yl)-N-(5-(pyrrolidin-1-yl)pentyl)quinazolin-4-amine	VWA5B2 PRR12 SH3PXD2B PRR36 SRCAP NOTCH3	1.70e-07	104	54	6	ctd:C000595015
Drug	Tridihexethyl chloride; Up 200; 11.4uM; MCF7; HT_HG-U133A	SETD1A RIN3 PRR36 LTBP4 PRRC2A NOTCH3	6.51e-06	194	54	6	3526_UP
Drug	Dihydroergotoxine mesylate [8067-24-1]; Down 200; 6.4uM; PC3; HT_HG-U133A	SETD1A RIN3 WIPF1 FBRS SRCAP NOTCH3	7.53e-06	199	54	6	4071_DN
Disease	platelet component distribution width	CCDC71L RIN3 WIPF1 SYNJ2 NYAP1 PRRC2A ANKS1A	2.68e-04	755	50	7	EFO_0007984
Disease	age at menopause	CCDC71L SH3PXD2B ZCCHC2 PRRC2A	1.71e-03	302	50	4	EFO_0004704
Disease	pulse pressure measurement	CCDC71L RIN3 WIPF1 ATXN7 ZCCHC2 SRCAP PLEKHA7 NOTCH3	2.21e-03	1392	50	8	EFO_0005763
Disease	brain measurement, neuroimaging measurement	VWA5B2 RIN3 LATS1 ATXN7 ANKS1A	2.35e-03	550	50	5	EFO_0004346, EFO_0004464

Protein segments in the cluster

Peptide	Gene	Start	Entry
PRPAPPRRPHPAPGP	TMEM62	36	Q0P6H9
RGPFMRRGPPFPPPP	CTAGE4	711	Q8IX94
RGPFMRRGPPFPPPP	CTAGE6	711	Q86UF2
RGPFMRRGPPFPPPP	CTAGE8	711	P0CG41
RGPFMRRGPPFPPPP	CTAGE9	711	A4FU28
RGPFMRRGPPFPPPP	CTAGE15	711	A4D2H0
PPRPLPPRPPAAQPR	ACR	331	P10323
PGPREPPPYQEPRPR	DDR1	476	Q08345
VRPRERPPPPAKPPP	ANKS1A	401	Q92625
RPRPRPPRPEPPPGL	RBM42	321	Q9BTD8
TRPPPPLPRFPRPPR	PRSS12	56	P56730
GRPYRPPSPPPPPSE	FOXH1	151	O75593
TPPPPPRGQTPPPRG	LATS1	246	O95835
PRRPGRPDHRPPRPP	MMP15	321	P51511
RPDHRPPRPPQPPPP	MMP15	326	P51511
PRAPPEPPDPGAPRP	LMTK3	821	Q96Q04
RRRPMSPPPPPPPVR	NOTCH3	11	Q9UM47
PPPPPRRTRPEDGGP	ATXN7	51	O15265
PRLGPRPVPPPRPES	CASKIN2	1121	Q8WXE0
PPARPAPRSPPPRSP	POM121	166	Q96HA1
APRSPPPRSPPPRSP	POM121	171	Q96HA1
SRPPRPSRPPPPTPR	ITCH	251	Q96J02
RPRPPPFLGPSPPDR	FBRS	341	Q9HAH7
PARPPPPPLPRRPST	LTBP4	1156	Q8N2S1
PPPLPRRPSTPRQGP	LTBP4	1161	Q8N2S1
PRGEAPPPPPPTARP	ARX	121	Q96QS3
PPPPPPTARPGERPD	ARX	126	Q96QS3
MPASAPPRRPRPPPP	KL	1	Q9UEF7
AARRRKPRPPPPPPP	CCDC71L	141	Q8N9Z2
RRPPPPATLPPEPEP	NLGN2	641	Q8NFZ4
PTSRWAPRRPPPPPP	RIN3	271	Q8TB24
PARERETPPPPPPPP	NYAP1	376	Q6ZVC0
LVPPRPPPPPVPPRR	RUSC1	396	Q9BVN2
PAPPREDPPRPTPRP	PLEKHH3	566	Q7Z736
TFRPGPEPPPPPPRR	PHETA1	196	Q8N4B1
PEPPPPPPRRRASAP	PHETA1	201	Q8N4B1
RPRPPQPPQRPPPPT	SYNJ2	1101	O15056
TPRPPGSPRPPPPVT	PRR36	26	Q9H6K5
SDIPPPGPPRVFPPR	PLEKHA7	571	Q6IQ23
PPGSEPPRRPPPAPH	PRRC2A	1701	P48634
PYRPGPPDPPPPPRH	PRR12	226	Q9ULL5
SFGGPRPRRQPPPPP	SRCAP	1866	Q6ZRS2
SHARRRRPPPPPPPP	SETD1A	1396	O15047
PPQPRRAAPTTPPPP	NCKIPSD	171	Q9NZQ3
RRRRDCRPPPPPPPP	ZCCHC2	36	Q9C0B9
PPVLPPPPRPPQRRC	nan	61	P0C880
PPAPPAPPTRPPRRC	THBS4	276	P35443
LQREPPRPEPPPPFP	UBN2	86	Q6ZU65
LPPPPPPPPRPVARR	ZBTB7B	186	O15156
MRGPPPPPRPPFGRP	TCERG1	56	O14776
PPPRPPFGRPPFDPN	TCERG1	61	O14776
PQQRPVVPPRRPPPP	SH3PXD2B	751	A1X283
NFPPPRPPPPSRPAP	WDR44	241	Q5JSH3
RPPPPSRPAPPPRKR	WDR44	246	Q5JSH3
ARPPVPPRPPRPPET	NDST2	66	P52849
GAPSEPPPPPEPRRP	SMIM44	116	A0A286YF18
PSERPPPPVRDPPGR	WIPF1	361	O43516
VPRRPGQRRPPPPPP	FASLG	36	P48023
PTEGPRRPPPRPPCR	VWA5B2	1016	Q8N398
SPERARPPPPPPPPA	TPRN	151	Q4KMQ1
PAARPPPPAPGPRPR	TIGD5	31	Q53EQ6
RPAPPPLVPQRPRPP	TTLL10	611	Q6ZVT0
RPQPRGPRTPPGPPP	VIRMA	176	Q69YN4
LPPPRPTPRPPVPPR	SF3B4	401	Q15427
PTPRPPVPPRGPLRG	SF3B4	406	Q15427
PLRGPRAPPRPGPPD	TMEM198	281	Q66K66