Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionryanodine-sensitive calcium-release channel activity

RYR2 RYR3

1.12e-044872GO:0005219
GeneOntologyMolecularFunctioncalcium-induced calcium release activity

RYR2 RYR3

2.78e-046872GO:0048763
GeneOntologyCellularComponentlaminin-5 complex

LAMA3 LAMA5

1.02e-044872GO:0005610
DomainConA-like_dom

CELSR2 SLIT3 TSPEAR LAMA3 LAMA5 TRIM14 NEURL4 RYR2 RYR3

4.96e-07219829IPR013320
DomainEGF

CELSR2 SLIT3 DLK2 LAMA3 LAMA5 NAGPA MEGF11 FBN3 GPR179

8.95e-07235829SM00181
DomainLamG

CELSR2 SLIT3 TSPEAR LAMA3 LAMA5

1.37e-0644825SM00282
DomainLaminin_G

CELSR2 SLIT3 TSPEAR LAMA3 LAMA5

5.50e-0658825IPR001791
DomainhEGF

CELSR2 DLK2 MEGF11 FBN3

6.52e-0628824PF12661
DomainEGF-like_dom

CELSR2 SLIT3 DLK2 LAMA3 LAMA5 NAGPA MEGF11 FBN3

1.36e-05249828IPR000742
DomainEGF_1

CELSR2 SLIT3 DLK2 LAMA3 LAMA5 NAGPA MEGF11 FBN3

1.61e-05255828PS00022
DomainLaminin_EGF

CELSR2 LAMA3 LAMA5 MEGF11

1.63e-0535824PF00053
DomainEGF_Lam

CELSR2 LAMA3 LAMA5 MEGF11

1.63e-0535824SM00180
DomainEGF-like_CS

CELSR2 SLIT3 DLK2 LAMA3 LAMA5 NAGPA MEGF11 FBN3

1.91e-05261828IPR013032
DomainEGF_2

CELSR2 SLIT3 DLK2 LAMA3 LAMA5 NAGPA MEGF11 FBN3

2.13e-05265828PS01186
DomainLAM_G_DOMAIN

CELSR2 SLIT3 LAMA3 LAMA5

2.27e-0538824PS50025
DomainLaminin_EGF

CELSR2 LAMA3 LAMA5 MEGF11

2.27e-0538824IPR002049
DomainLaminin_G_2

CELSR2 SLIT3 LAMA3 LAMA5

2.80e-0540824PF02210
DomainRyanrecept_TM4-6

RYR2 RYR3

5.70e-053822IPR009460
DomainRyR

RYR2 RYR3

5.70e-053822PF02026
DomainRyanodine_rcpt

RYR2 RYR3

5.70e-053822IPR003032
DomainRR_TM4-6

RYR2 RYR3

5.70e-053822PF06459
DomainRyan_recept

RYR2 RYR3

5.70e-053822IPR013333
DomainGrowth_fac_rcpt_

CELSR2 SLIT3 LAMA3 LAMA5 FBN3 GPR179

6.40e-05156826IPR009030
DomainLaminin_aI

LAMA3 LAMA5

1.89e-045822IPR009254
DomainLaminin_I

LAMA3 LAMA5

1.89e-045822PF06008
DomainLaminin_II

LAMA3 LAMA5

1.89e-045822PF06009
DomainLaminin_domII

LAMA3 LAMA5

1.89e-045822IPR010307
DomainEGF

CELSR2 SLIT3 DLK2 NAGPA FBN3

2.32e-04126825PF00008
DomainRIH_assoc

RYR2 RYR3

2.82e-046822PF08454
DomainRIH_assoc-dom

RYR2 RYR3

2.82e-046822IPR013662
DomainRIH_dom

RYR2 RYR3

2.82e-046822IPR000699
DomainIns145_P3_rcpt

RYR2 RYR3

2.82e-046822IPR014821
DomainRyanodine_recept-rel

RYR2 RYR3

2.82e-046822IPR015925
Domain-

RYR2 RYR3

2.82e-0468221.25.10.30
DomainRYDR_ITPR

RYR2 RYR3

2.82e-046822PF01365
DomainIns145_P3_rec

RYR2 RYR3

2.82e-046822PF08709
DomainEGF_LAM_2

CELSR2 LAMA3 LAMA5

3.04e-0430823PS50027
DomainEGF_LAM_1

CELSR2 LAMA3 LAMA5

3.04e-0430823PS01248
DomainLAMININ_IVA

LAMA3 LAMA5

5.24e-048822PS51115
DomainLaminin_B

LAMA3 LAMA5

5.24e-048822PF00052
DomainLamB

LAMA3 LAMA5

5.24e-048822SM00281
DomainLaminin_IV

LAMA3 LAMA5

5.24e-048822IPR000034
DomainEGF_3

CELSR2 SLIT3 DLK2 NAGPA MEGF11 FBN3

5.87e-04235826PS50026
Domain-

CELSR2 SLIT3 LAMA3 LAMA5

8.11e-04958242.60.120.200
DomainMIR

RYR2 RYR3

8.38e-0410822PS50919
DomainMIR

RYR2 RYR3

8.38e-0410822PF02815
DomainMIR

RYR2 RYR3

8.38e-0410822SM00472
DomainMIR_motif

RYR2 RYR3

8.38e-0410822IPR016093
DomainEGF-type_Asp/Asn_hydroxyl_site

CELSR2 SLIT3 DLK2 FBN3

1.22e-03106824IPR000152
DomainIon_trans_dom

CACNA1F KCNC1 RYR2 RYR3

1.60e-03114824IPR005821
DomainIon_trans

CACNA1F KCNC1 RYR2 RYR3

1.60e-03114824PF00520
DomainEGF_CA

CELSR2 SLIT3 DLK2 FBN3

2.05e-03122824SM00179
DomainEGF-like_Ca-bd_dom

CELSR2 SLIT3 DLK2 FBN3

2.17e-03124824IPR001881
DomainLaminin_N

LAMA3 LAMA5

2.20e-0316822IPR008211
DomainLAMININ_NTER

LAMA3 LAMA5

2.20e-0316822PS51117
DomainLaminin_N

LAMA3 LAMA5

2.20e-0316822PF00055
DomainLamNT

LAMA3 LAMA5

2.20e-0316822SM00136
DomainEGF_extracell

DLK2 NAGPA MEGF11

2.33e-0360823IPR013111
DomainEGF_2

DLK2 NAGPA MEGF11

2.33e-0360823PF07974
DomainA/G_cyclase_CS

GUCY2F ADCY5

2.48e-0317822IPR018297
DomainNucleotide_cyclase

GUCY2F ADCY5

2.78e-0318822IPR029787
Domain-

GUCY2F ADCY5

2.78e-03188223.30.70.1230
DomainGUANYLATE_CYCLASE_1

GUCY2F ADCY5

3.10e-0319822PS00452
DomainGuanylate_cyc

GUCY2F ADCY5

3.10e-0319822PF00211
DomainGUANYLATE_CYCLASE_2

GUCY2F ADCY5

3.10e-0319822PS50125
DomainA/G_cyclase

GUCY2F ADCY5

3.10e-0319822IPR001054
DomainCYCc

GUCY2F ADCY5

3.10e-0319822SM00044
DomainEPHD

KMT2D RAI1

4.15e-0322822PS51805
Pubmed

Altered ryanodine receptor expression in mild cognitive impairment and Alzheimer's disease.

RYR2 RYR3

6.48e-06289221531043
Pubmed

Modulation of calcium signalling by dominant negative splice variant of ryanodine receptor subtype 3 in native smooth muscle cells.

RYR2 RYR3

6.48e-06289216678258
Pubmed

In situ-RT-PCR and immunohistochemistry for the localisation of the mRNA of the alpha 3 chain of laminin and laminin-5 during human organogenesis.

LAMA3 LAMA5

6.48e-06289212382139
Pubmed

Biological function of laminin-5 and pathogenic impact of its deficiency.

LAMA3 LAMA5

6.48e-06289217000025
Pubmed

Tissue-specific alternative splicing of mouse brain type ryanodine receptor/calcium release channel mRNA.

RYR2 RYR3

6.48e-0628928898078
Pubmed

The mouse sino-atrial node expresses both the type 2 and type 3 Ca(2+) release channels/ryanodine receptors.

RYR2 RYR3

6.48e-06289214550562
Pubmed

Decreased expression of ryanodine receptors alters calcium-induced calcium release mechanism in mdx duodenal myocytes.

RYR2 RYR3

6.48e-06289214985349
Pubmed

Type 1 and type 3 ryanodine receptors are selectively involved in muscarinic antinociception in mice: an antisense study.

RYR2 RYR3

1.94e-05389218403125
Pubmed

Globular domains 4/5 of the laminin alpha3 chain mediate deposition of precursor laminin 5.

LAMA3 LAMA5

1.94e-05389215316072
Pubmed

Heterogeneous gene expression and functional activity of ryanodine receptors in resistance and conduit pulmonary as well as mesenteric artery smooth muscle cells.

RYR2 RYR3

1.94e-05389218434746
Pubmed

Control of Neuronal Ryanodine Receptor-Mediated Calcium Signaling by Calsenilin.

RYR2 RYR3

1.94e-05389229730765
Pubmed

SPRY domains in ryanodine receptors (Ca(2+)-release channels).

RYR2 RYR3

1.94e-0538929204703
Pubmed

The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues.

RYR2 RYR3

1.94e-0538927876312
Pubmed

Ryanodine receptors are expressed in epidermal keratinocytes and associated with keratinocyte differentiation and epidermal permeability barrier homeostasis.

RYR2 RYR3

1.94e-05389221881589
Pubmed

Isoform-dependent formation of heteromeric Ca2+ release channels (ryanodine receptors).

RYR2 RYR3

1.94e-05389212213830
Pubmed

Expression of the ryanodine receptor type 3 calcium release channel during development and differentiation of mammalian skeletal muscle cells.

RYR2 RYR3

1.94e-0538929242641
Pubmed

Bidirectional coupling between ryanodine receptors and Ca2+ release-activated Ca2+ (CRAC) channel machinery sustains store-operated Ca2+ entry in human T lymphocytes.

RYR2 RYR3

1.94e-05389222948152
Pubmed

Developmental changes in expression of the three ryanodine receptor mRNAs in the mouse brain.

RYR2 RYR3

1.94e-05389210788707
Pubmed

RYR2 proteins contribute to the formation of Ca(2+) sparks in smooth muscle.

RYR2 RYR3

1.94e-05389215024040
Pubmed

Calcineurin upregulates local Ca(2+) signaling through ryanodine receptor-1 in airway smooth muscle cells.

RYR2 RYR3

1.94e-05389225239916
Pubmed

Ca(2+)-induced Ca2+ release in myocytes from dyspedic mice lacking the type-1 ryanodine receptor.

RYR2 RYR3

1.94e-0538927621815
Pubmed

A gene-specific cerebral types 1, 2, and 3 RyR protein knockdown induces an antidepressant-like effect in mice.

RYR2 RYR3

1.94e-05389218643873
Pubmed

Identification of mutations in the cardiac ryanodine receptor gene in families affected with arrhythmogenic right ventricular cardiomyopathy type 2 (ARVD2).

RYR2 RYR3

1.94e-05389211159936
Pubmed

Molecular identification of the ryanodine receptor pore-forming segment.

RYR2 RYR3

1.94e-05389210473538
Pubmed

Chromosomal localization of murine ryanodine receptor genes RYR1, RYR2, and RYR3 by in situ hybridization.

RYR2 RYR3

1.94e-0538927959768
Pubmed

The organization of proteins in the human red blood cell membrane. A review.

RYR2 RYR3

1.94e-0538924600883
Pubmed

Regulation of mouse egg activation: presence of ryanodine receptors and effects of microinjected ryanodine and cyclic ADP ribose on uninseminated and inseminated eggs.

RYR2 RYR3

1.94e-0538927635066
Pubmed

Localization of laminin-5, HD1/plectin, and BP230 in the submandibular glands of developing and adult mice.

LAMA3 LAMA5

3.87e-05489210651091
Pubmed

A glutathione deficit alters dopamine modulation of L-type calcium channels via D2 and ryanodine receptors in neurons.

RYR2 RYR3

3.87e-05489218206662
Pubmed

Human mast cells adhere to and migrate on epithelial and vascular basement membrane laminins LM-332 and LM-511 via alpha3beta1 integrin.

LAMA3 LAMA5

3.87e-05489219752234
Pubmed

Ryanodine receptor calcium release channels: lessons from structure-function studies.

RYR2 RYR3

3.87e-05489223413940
Pubmed

Membrane type 1 matrix metalloprotease cleaves laminin-10 and promotes prostate cancer cell migration.

LAMA5 MMP14

3.87e-05489215967115
Pubmed

Requirement for the ryanodine receptor type 3 for efficient contraction in neonatal skeletal muscles.

RYR2 RYR3

3.87e-0548929384575
Pubmed

Partial cloning and differential expression of ryanodine receptor/calcium-release channel genes in human tissues including the hippocampus and cerebellum.

RYR2 RYR3

3.87e-0548929607712
Pubmed

Conserved and divergent functions of Nfix in skeletal muscle development during vertebrate evolution.

RYR2 RYR3

3.87e-05489223482488
Pubmed

Expression and distribution of laminin alpha1 and alpha2 chains in embryonic and adult mouse tissues: an immunochemical approach.

LAMA3 LAMA5

6.44e-05589211969289
Pubmed

Sorcin is an early marker of neurodegeneration, Ca2+ dysregulation and endoplasmic reticulum stress associated to neurodegenerative diseases.

RYR2 RYR3

6.44e-05589233060591
Pubmed

Differential expression of five laminin alpha (1-5) chains in developing and adult mouse kidney.

LAMA3 LAMA5

6.44e-0558929415429
Pubmed

Presenilins regulate calcium homeostasis and presynaptic function via ryanodine receptors in hippocampal neurons.

RYR2 RYR3

6.44e-05589223918386
Pubmed

Complete sequence, recombinant analysis and binding to laminins and sulphated ligands of the N-terminal domains of laminin alpha3B and alpha5 chains.

LAMA3 LAMA5

6.44e-05589211829758
Pubmed

Protein kinase C-epsilon regulates local calcium signaling in airway smooth muscle cells.

RYR2 RYR3

6.44e-05589219011160
Pubmed

Differential expression of laminin alpha chains during murine tooth development.

LAMA3 LAMA5

6.44e-0558929389447
Pubmed

Membrane depolarization causes a direct activation of G protein-coupled receptors leading to local Ca2+ release in smooth muscle.

RYR2 RYR3

9.65e-05689219549818
Pubmed

Rectification of muscle and nerve deficits in paralyzed ryanodine receptor type 1 mutant embryos.

RYR2 RYR3

9.65e-05689226025922
Pubmed

Roles of I(f) and intracellular Ca2+ release in spontaneous activity of ventricular cardiomyocytes during murine embryonic development.

RYR2 RYR3

9.65e-05689223463619
Pubmed

HIV-protein-mediated alterations in T cell interactions with the extracellular matrix proteins and endothelium.

LAMA3 LAMA5

9.65e-0568929597096
Pubmed

FKBP12.6 and cADPR regulation of Ca2+ release in smooth muscle cells.

RYR2 RYR3

9.65e-05689214592808
Pubmed

A calcium-induced calcium release mechanism supports luteinizing hormone-induced testosterone secretion in mouse Leydig cells.

RYR2 RYR3

9.65e-05689220519450
Pubmed

Essential Roles of Intracellular Calcium Release Channels in Muscle, Brain, Metabolism, and Aging.

RYR2 RYR3

9.65e-05689225966694
Pubmed

Genotype and phenotype of 101 dutch patients with congenital stationary night blindness.

CACNA1F GPR179

9.65e-05689223714322
Pubmed

HIV-1 Tat activates neuronal ryanodine receptors with rapid induction of the unfolded protein response and mitochondrial hyperpolarization.

RYR2 RYR3

9.65e-05689219009018
Pubmed

IP3Rs are sufficient for dendritic cell Ca2+ signaling in the absence of RyR1.

RYR2 RYR3

9.65e-05689216844763
Pubmed

Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.

CACNA1F RYR2 RYR3

1.28e-043889330786075
Pubmed

Skeletal and hematological anomalies in HYAL2-deficient mice: a second type of mucopolysaccharidosis IX?

RASSF1 IFRD2

1.35e-04789218772348
Pubmed

Developmental expression of the calcium release channels during early neurogenesis of the mouse cerebral cortex.

RYR2 RYR3

1.35e-04789211860456
Pubmed

Human immunodeficiency virus-1 Tat activates calpain proteases via the ryanodine receptor to enhance surface dopamine transporter levels and increase transporter-specific uptake and Vmax.

RYR2 RYR3

1.35e-04789220962236
Pubmed

Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

NEURL4 MEGF11 FBN3 RAI1

1.69e-0410789411347906
Pubmed

Expression and localization of laminin-5 subunits during mouse tooth development.

LAMA3 LAMA5

1.79e-0488929489770
Pubmed

Roles of IP3R and RyR Ca2+ channels in endoplasmic reticulum stress and beta-cell death.

RYR2 RYR3

1.79e-04889219033399
Pubmed

Roles for laminin in embryogenesis: exencephaly, syndactyly, and placentopathy in mice lacking the laminin alpha5 chain.

LAMA3 LAMA5

1.79e-0488929852162
Pubmed

Cloning and expression analyses of mouse dystroglycan gene: specific expression in maternal decidua at the peri-implantation stage.

LAMA3 LAMA5

1.79e-0488928872465
Pubmed

Spatial and temporal control of laminin-332 and -511 expressions during hair morphogenesis.

LAMA3 LAMA5

1.79e-04889223529140
Pubmed

Sequential docking, molecular differentiation, and positioning of T-Tubule/SR junctions in developing mouse skeletal muscle.

RYR2 RYR3

1.79e-04889211784029
Pubmed

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

TMEM25 EEF1AKMT4-ECE2 SEMA5B SLIT3 DLK2 CHRD NXPH4 MEGF11 ALG2 SLC27A3

2.14e-04985891012975309
Pubmed

Identification of high-molecular-weight proteins with multiple EGF-like motifs by motif-trap screening.

CELSR2 SLIT3

2.30e-0498929693030
Pubmed

Distribution of the ten known laminin chains in the pathways and targets of developing sensory axons.

LAMA3 LAMA5

2.88e-04108929034910
Pubmed

The Auxiliary Calcium Channel Subunit α2δ4 Is Required for Axonal Elaboration, Synaptic Transmission, and Wiring of Rod Photoreceptors.

CACNA1F GPR179

3.51e-041189228262416
Pubmed

Beta4 integrin is required for hemidesmosome formation, cell adhesion and cell survival.

LAMA3 LAMA5

3.51e-04118928707838
Pubmed

Laminin alpha 5 is required for lobar septation and visceral pleural basement membrane formation in the developing mouse lung.

LAMA3 LAMA5

3.51e-041189212051813
Pubmed

Regional differences in the expression of laminin isoforms during mouse neural tube development.

LAMA3 LAMA5

3.51e-041189221524702
Pubmed

The parvalbumin/somatostatin ratio is increased in Pten mutant mice and by human PTEN ASD alleles.

KCNC1 NPAS1

3.51e-041189225937288
Pubmed

New molecular components supporting ryanodine receptor-mediated Ca(2+) release: roles of junctophilin and TRIC channel in embryonic cardiomyocytes.

RYR2 RYR3

4.20e-041289219095005
Pubmed

Molecular dissection of laminin alpha 5 in vivo reveals separable domain-specific roles in embryonic development and kidney function.

LAMA3 LAMA5

4.20e-041289216750824
Pubmed

Distribution and function of laminins in the neuromuscular system of developing, adult, and mutant mice.

LAMA3 LAMA5

4.20e-04128929396756
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ZNF512B SEMA5B SLIT3 LAMA5 TNKS1BP1 RAI1 NUAK2

4.26e-0452989714621295
Pubmed

BRCA2 mediates centrosome cohesion via an interaction with cytoplasmic dynein.

CFH TERT GPR179

4.29e-045789327433848
Pubmed

Fukutin-related protein alters the deposition of laminin in the eye and brain.

LAMA3 LAMA5

4.96e-041389221900571
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

KMT2D FOXK2 CELSR2 IFRD2 ZBTB4 LAMA5 TNKS1BP1 IDUA MMP14 RAI1

5.28e-041105891035748872
Pubmed

Membrane-type MMPs are indispensable for placental labyrinth formation and development.

LAMA5 MMP14

5.78e-041489220858856
Pubmed

The laminin alpha chains: expression, developmental transitions, and chromosomal locations of alpha1-5, identification of heterotrimeric laminins 8-11, and cloning of a novel alpha3 isoform.

LAMA3 LAMA5

5.78e-04148929151674
Pubmed

Basement membrane composition in the early mouse embryo day 7.

LAMA3 LAMA5

6.65e-041589215895400
Pubmed

AP-2α and AP-2β cooperatively function in the craniofacial surface ectoderm to regulate chromatin and gene expression dynamics during facial development.

NKD1 KREMEN2

6.65e-041589235333176
Pubmed

Localization of basement membrane-associated protein isoforms during development of the ocular surface of mouse eye.

LAMA3 LAMA5

6.65e-04158929264260
Pubmed

The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: identification and evaluation of the resident candidate tumor suppressor genes. The International Lung Cancer Chromosome 3p21.3 Tumor Suppressor Gene Consortium.

RASSF1 IFRD2

6.65e-041589211085536
Pubmed

Laminin alpha5 is necessary for submandibular gland epithelial morphogenesis and influences FGFR expression through beta1 integrin signaling.

LAMA3 LAMA5

7.59e-041689217601529
Pubmed

ADAMTS18 Deficiency Affects Neuronal Morphogenesis and Reduces the Levels of Depression-like Behaviors in Mice.

LAMA3 LAMA5

7.59e-041689230579834
Pubmed

TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination.

LAMA3 LAMA5 IDUA MMP14

8.52e-0416489432409323
Pubmed

Mouse Nkd1, a Wnt antagonist, exhibits oscillatory gene expression in the PSM under the control of Notch signaling.

NKD1 SLIT3

8.59e-041789215511637
Pubmed

DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

FOXK2 ARHGAP23 GPR179

9.21e-047489316625196
Pubmed

Amplification of extracellular matrix and oncogenes in tat-transfected human salivary gland cell lines with expression of laminin, fibronectin, collagens I, III, IV, c-myc and p53.

LAMA3 LAMA5

9.65e-041889211311202
Pubmed

Laminin and integrin expression in the ventral ectodermal ridge of the mouse embryo: implications for regulation of BMP signalling.

LAMA3 LAMA5

1.19e-032089222911573
Pubmed

Genetic variation in MicroRNA genes and risk of oral premalignant lesions.

MAP3K12 INKA2

1.19e-032089219851984
Pubmed

Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy.

KMT2D FOXK2

1.19e-032089229785026
Pubmed

Specific 3-O-sulfated heparan sulfate domains regulate salivary gland basement membrane metabolism and epithelial differentiation.

LAMA3 LAMA5 MMP14

1.20e-038189339217171
Pubmed

Congenital heart defect causing mutation in Nkx2.5 displays in vivo functional deficit.

ETV2 RYR2

1.32e-032189228302382
Pubmed

PDGFRβ regulates craniofacial development through homodimers and functional heterodimers with PDGFRα.

LAMA3 LAMA5

1.32e-032189227856617
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

ZNF512B CFH USP13 ZBTB4 RIPPLY3 PDCD7 RYR3 ME3 PINK1 ZNF662

1.65e-031285891035914814
Pubmed

Dysregulation of TBX1 dosage in the anterior heart field results in congenital heart disease resembling the 22q11.2 duplication syndrome.

RIPPLY3 ETV2

1.87e-032589229509905
Pubmed

Cannabinoid inhibits HIV-1 Tat-stimulated adhesion of human monocyte-like cells to extracellular matrix proteins.

LAMA3 LAMA5

2.02e-032689224742657
Pubmed

Adamts18 modulates the development of the aortic arch and common carotid artery.

LAMA3 LAMA5

2.02e-032689234189436
GeneFamilyRyanodine receptors|Protein phosphatase 1 regulatory subunits

RYR2 RYR3

2.07e-053482287
GeneFamilyLaminin subunits

LAMA3 LAMA5

4.48e-0412482626
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

PLEKHG4B ARHGAP23 ARHGAP12 PLEKHS1

2.15e-03206484682
CoexpressionGSE34515_CD16_NEG_VS_POS_MONOCYTE_UP

CACNA1F NKD1 RP1L1 IFRD2 COLCA1 NAGPA SLC27A3

5.50e-06200897M8764
CoexpressionDESCARTES_FETAL_LIVER_MESOTHELIAL_CELLS

CPAMD8 NKD1 SLIT3 PNMA8A LAMA3 LAMA5 FBN3 RYR2

1.15e-05313898M40228
CoexpressionNABA_ECM_GLYCOPROTEINS

SLIT3 TSPEAR KCP LAMA3 LAMA5 FBN3

5.62e-05196896M3008
CoexpressionGSE33374_CD8_ALPHAALPHA_VS_ALPHABETA_CD161_HIGH_TCELL_UP

SEMA5B MAP3K12 NEURL4 RAI1 NPAS1 GGT5

6.11e-05199896M8538
CoexpressionHALLMARK_KRAS_SIGNALING_DN

CACNA1F KMT2D CELSR2 DLK2 IDUA RYR2

6.29e-05200896M5956
ToppCell343B-Epithelial_cells-Epithelial-E_(AT2)-|343B / Donor, Lineage, Cell class and subclass (all cells)

TMEM25 CACNA1F USP13 LAMA3 CHRD LAMA5 FBN3

1.72e-0814589780684ec249fa445c1b35f94608a4a6824d53f2d9
ToppCell343B-Epithelial_cells-Epithelial-E_(AT2)|343B / Donor, Lineage, Cell class and subclass (all cells)

TMEM25 CACNA1F USP13 LAMA3 CHRD LAMA5 FBN3

1.72e-08145897cb534333fba44b241b14fb0d7b74e843f4e7f9f8
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CFH ADAMTS19 NKD1 ARHGAP23 TSPEAR TMEM200C RYR3

4.76e-08168897315ca578c945aeeb77acda2727f3e6db8b43f43e
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CFH ADAMTS19 NKD1 ARHGAP23 TSPEAR TMEM200C RYR3

7.34e-081798977394e77e665bf16d3733df91bb12907be460ab44
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CFH ADAMTS19 NKD1 ARHGAP23 TSPEAR TMEM200C RYR3

9.19e-08185897b848b63aff4d9dbb9e66a85876d4c7c6dacd0579
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AGXT2 ADAMTS19 CHRD MESP2 NXPH4 RYR3

1.08e-061678963dfec2fcc36caa6e394efae5e540a6fa28759977
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AGXT2 ADAMTS19 CHRD MESP2 NXPH4 RYR3

1.08e-0616789695b3b5ba3414729f0460a26a0deca48de0cbe33e
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AGXT2 ADAMTS19 CHRD MESP2 NXPH4 RYR3

1.08e-061678969480739587d51e67a281778b9bddd7b5ffc3ad92
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS19 NKD1 ARHGAP23 TSPEAR TMEM200C RYR3

1.11e-06168896fc80e4fecfc92458eb627013a983041d8ca025a9
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS19 NKD1 ARHGAP23 TSPEAR TMEM200C RYR3

1.11e-06168896e96859dbf51cf8c4def8ee8db132f4d874fb4381
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CFH ADAMTS19 NKD1 ARHGAP23 TMEM200C RYR3

1.83e-06183896848fc6dd129150897ee339343e83c645b6e779eb
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CFH ADAMTS19 NKD1 TSPEAR TMEM200C RYR3

1.83e-061838967c4b775f351794a3de06bd503eecbc8ae8577c44
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS19 NKD1 ARHGAP23 TSPEAR TMEM200C RYR3

1.95e-061858969197f074e769d54031ec41abfc65fcc0c6552c7e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS19 NKD1 ARHGAP23 TSPEAR TMEM200C RYR3

1.95e-06185896ce7d62394b09c26ca65b8cdb280afec5e25bbb62
ToppCell3'-Adult-LargeIntestine-Mesenchymal-Pericytes-Pericyte|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NKD1 SEMA5B C11orf96 CHRD ADCY5 GGT5

2.08e-06187896150023e6a50c9da461f2321074d2d5e96caafb06
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CFH ARHGAP23 SEMA5B SLIT3 LAMA3 ADCY5

2.14e-06188896b21e93a70583c30d05c0833cd3d4d4bca44a039e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CFH ARHGAP23 SEMA5B SLIT3 LAMA3 ADCY5

2.14e-06188896874404a4fd9aa42873f6c53dc42da22d3b0fdb9e
ToppCellParenchymal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SEMA5B C11orf96 SLIT3 CHRD ADCY5 RYR2

2.81e-061978963f078be0b0f5e16edfb6d517beb20ac6178767f0
ToppCellBronchial-10x5prime-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CFH C11orf96 SLIT3 ADCY5 RYR2 GGT5

2.89e-06198896dc6d9032c5029527e184ac13b887c0c1f22ef1c0
ToppCellParenchymal-10x5prime-Stromal-Peri/Epineurial_|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ZNF512B CFH ADAMTS19 ZNF517 VSIG10L CHRD

3.06e-062008964c3c11dd5e71ebc3d62264eeaeb71a850b149779
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

CFH COLCA1 PLEKHS1 VSIG10L2 NXPH4

1.36e-051528951b2a39ae159e79f1fb18d6d164bd7acab5299fca
ToppCellwk_15-18-Epithelial-Proximal_epithelial-basal_intermediate_|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

TSPEAR DLK2 LAMA3 SCART1 LRRC74A

1.64e-0515889598712ed7e8e65e8c5ff9318cf0e0a04e271a055d
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell-D231|Adult / Lineage, Cell type, age group and donor

NKD1 SEMA5B SLIT3 ADCY5 RYR2

1.64e-051588958d64c0c9de910a3f4658778642d183c8b9b6f6a2
ToppCellfacs-Lung-Endomucin-24m-Lymphocytic-mature_NK_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AGXT2 KCNC1 CHRD NEURL4 RYR3

1.69e-051598954000ed0d3b7d488722bcd0042fa2ff4405aaab82
ToppCellfacs-Lung-Endomucin-24m-Lymphocytic-Natural_Killer_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AGXT2 KCNC1 CHRD NEURL4 RYR3

1.69e-051598957619d0d49738dd08daf01b42664691a5323aa793
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell-D122|Adult / Lineage, Cell type, age group and donor

SEMA5B SLIT3 CHRD ADCY5 RYR2

1.74e-05160895fd14dfeb7021a4b7299371854dc8fc1fd66c8dae
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6b-L6b_Hsd17b2|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RP1L1 LRRC74A NXPH4 NUAK2

1.82e-0578894e5dbb0986cbee58fb1e5e464a3b003c4136246e7
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l22|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AGXT2 KCNC1 CHRD ALG2 RYR3

2.08e-05166895bcdaab49bde5beba750b76fdcc3781a3c12c4fff
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-mature_NK_T_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AGXT2 KCNC1 CHRD ALG2 RYR3

2.08e-051668955e3b998d740b24f790fad37350d704ca0ea10b77
ToppCellfacs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l15|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PPP1R3D TRMT44 RP1L1 NXPH4 MEGF11

2.20e-05168895a8958b94ffc3423d56c250796dd253884b46f9d9
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CFH C11orf96 SLIT3 RIPPLY3 GGT5

2.47e-051728951ef243bce63d841c25e4b74d029d1377f84bcc3d
ToppCellAdult-Mesenchymal-pericyte_cell-D231|Adult / Lineage, Cell type, age group and donor

SEMA5B SLIT3 KCP ADCY5 RYR2

2.47e-05172895858cee96c1c06160863b4adcd7023c0d678bd50f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CFH ADAMTS19 ARHGAP23 TMEM200C RYR3

2.47e-051728956c17a1e586a72d1bd80c20c06370429c61dc9f85
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CFH C11orf96 SLIT3 RIPPLY3 GGT5

2.47e-05172895ab1c81be29f93ca8920c6ab5ab92f497a9256d3f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS19 NKD1 TSPEAR TMEM200C RYR3

2.47e-05172895381ae1c3c07d0a424f43455ec571653b192a946a
ToppCellAdult-Epithelial-club_cell-D175|Adult / Lineage, Cell type, age group and donor

CFH PLEKHG4B CPAMD8 RAI1 GGT5

2.83e-05177895d652b7d84fe6aa38319d8d5adc72c70441bd0088
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS19 NKD1 TSPEAR TMEM200C RYR3

2.83e-051778954d2cdb57b427a42085c5f9affa0967b15e84dec3
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS19 NKD1 TSPEAR TMEM200C RYR3

2.91e-05178895edc7143dc9959d36057cb9471681a23afcbc8cce
ToppCellfacs-Lung-nan-3m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNKS1BP1 ADCY5 NXPH4 INKA2 GPR179

2.99e-051798957078022e60faa86444f2a2c6eb9f767cc66b5cfa
ToppCellfacs-Lung-nan-3m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNKS1BP1 ADCY5 NXPH4 INKA2 GPR179

2.99e-05179895d4a975d8ffa5e77fb5c0ec05bf9c8f843c77ce07
ToppCelldroplet-Heart-nan-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C11orf96 PLEKHS1 TNKS1BP1 ADCY5 NXPH4

3.07e-0518089578fdcfb3fdbf36469cae78407cda5bd0996930d8
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CFH ADAMTS19 ARHGAP12 SLIT3 RYR3

3.07e-05180895e8841ef1239f9ee73ac4f4e11faca0742694f368
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CFH NKD1 C11orf96 SLIT3 GGT5

3.15e-05181895c6d2a13df3b74fade3b0c71e285b4c14c8e52413
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS19 NKD1 TSPEAR TMEM200C RYR3

3.15e-051818955bf7aa43f6e6ecce15c95928b91195544d6928c4
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CFH NKD1 C11orf96 SLIT3 GGT5

3.15e-05181895c62b0a2422377ffadaab63edd538e87a06fa5017
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS19 NKD1 TSPEAR TMEM200C RYR3

3.15e-051818958e751f5d7cd2d328ec0196d874e8a507e8c4e1a9
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CFH PLEKHG4B CPAMD8 COLCA1 PLEKHS1

3.23e-05182895215c303df42f13597b2c7a95cb157c6bc7aca9a1
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_VWA2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CFH ADAMTS19 SEMA5B SLIT3 RYR3

3.23e-0518289572e65a23cd36085bc880087d3cae92395de918a1
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CFH ADAMTS19 SEMA5B SLIT3 RYR3

3.23e-0518289505c167158815bf25d509df59ab386e1990712765
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell-D175|Adult / Lineage, Cell type, age group and donor

PLEKHG4B SLIT3 SCART1 MAP3K12 RYR3

3.23e-05182895ad4d74d8b19976e1ccc3c5ba8013199338cf6fd8
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS19 NKD1 TSPEAR TMEM200C RYR3

3.32e-05183895612d93df03252d4d2ccdce5a9bc162cfd9172a1a
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Stroma____kidney_mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH NKD1 C11orf96 SLIT3 ADCY5

3.32e-051838958de4b616a06be03e1cb6ae6a9ce6bf06485629d3
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS19 NKD1 TSPEAR TMEM200C RYR3

3.32e-05183895eb559ae3ae252d9365c24ef557dd49b78ed6d898
ToppCellwk_20-22-Epithelial-Proximal_epithelial-Late_airway_progenitor|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

CFH CPAMD8 CELSR2 LAMA5 FBN3

3.32e-051838950cea883a8a79fc58abcb26b08bf5db9d3d60f7d4
ToppCellAdult-Epithelial-club_cell-D231|Adult / Lineage, Cell type, age group and donor

CFH PLEKHG4B CPAMD8 COLCA1 PLEKHS1

3.68e-05187895ee59d7d3de5879738ff0b9c3ea5e4847fb48cb86
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PLEKHG4B CPAMD8 LAMA3 LAMA5 FBN3

3.68e-051878954ae7465174e0295d2c3b614b321a3b2f514dd22a
ToppCell15-Trachea-Epithelial-Secretory_progenitor|Trachea / Age, Tissue, Lineage and Cell class

CFH CPAMD8 NXPH4 FBN3 GGT5

3.68e-05187895be9fce9e74b2f170a2067f1b31d802912a578329
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

NKD1 SLIT3 LAMA3 RYR2 RYR3

3.77e-0518889534e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l39|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PPP1R3D SEMA5B C11orf96 LAMA5 RYR2

3.77e-05188895a5e7a363fbd5ae4d9312cf6f9941413d6a5c0b4d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NKD1 C11orf96 SLIT3 ADCY5 RYR2

3.87e-05189895127ad2ba3e794df8cce2eee3e4171bccb5aad51b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NKD1 C11orf96 SLIT3 ADCY5 RYR2

3.87e-051898952cfb4d12f75678d1619f4743838a0e954bd57761
ToppCellAdult-Epithelial-club_cell|Adult / Lineage, Cell type, age group and donor

CFH PLEKHG4B CPAMD8 COLCA1 PLEKHS1

3.97e-05190895756bff697d30aec56c0ebfca94295f084a15bf37
ToppCellEpithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|World / Lineage, Cell type, age group and donor

CPAMD8 CELSR2 LAMA3 LAMA5 FBN3

4.07e-05191895d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NKD1 C11orf96 SLIT3 ADCY5 RYR2

4.17e-05192895bfab13793e54de2550ee171397f7ece0625cdb4a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NKD1 C11orf96 SLIT3 ADCY5 RYR2

4.17e-05192895b54b0d5b88139905521c8d5d58332e89c08d589c
ToppCelldroplet-Heart-HEART-1m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NKD1 SEMA5B C11orf96 ADCY5 FAM241A

4.17e-05192895eb9a0b3d32f90f8b95905c740aab21639dae5cbd
ToppCellEpithelial-club_cell|World / Lineage, Cell type, age group and donor

CFH PLEKHG4B CPAMD8 COLCA1 PLEKHS1

4.27e-051938952bdd09004fa433550958ec42ba4b06271a4aaf7c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NKD1 C11orf96 SLIT3 ADCY5 RYR2

4.38e-051948955c3b2b05d1e4f146551fe4c920263d8e6ca34de3
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NKD1 C11orf96 SLIT3 ADCY5 RYR2

4.38e-05194895ab9cad697f9209d2889bc02b43b502dfeb2ebfef
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CFH ADAMTS19 ARHGAP23 SLIT3 TMEM200C

4.38e-051948951374600957c7d7f0b05fd2c1186f521b9096d4ef
ToppCelldroplet-Liver-LIVER-NPC-1m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NKD1 ARHGAP23 C11orf96 RIPPLY3 CCDC85B

4.49e-0519589585df110f753f58ab017018c54ee454edb4428e29
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Smooth_muscle|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NKD1 C11orf96 SLIT3 CHRD ADCY5

4.60e-05196895cda3681f032f740cb09c64c62b9153cb62dbb5d2
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Smooth_muscle-Smooth_muscle_L.2.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NKD1 C11orf96 SLIT3 CHRD ADCY5

4.60e-05196895b55aa507429ddce89ad4f42ab6daeca2f34fd676
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NKD1 C11orf96 SLIT3 CHRD ADCY5

4.60e-05196895208ddedd29e1b9ca89cbb9b527c2e193a44cada2
ToppCellCOVID-19-lung-Pericytes/_Smooth_Muscle|COVID-19 / Disease (COVID-19 only), tissue and cell type

NKD1 C11orf96 SLIT3 ADCY5 RYR2

4.60e-05196895754a3613340932563cd8424d775e18b93c3a1aaa
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CFH C11orf96 SLIT3 ADCY5 RYR2

4.71e-05197895cfb3dc4b401800e33c82cfc3baee69dbbd16ac8c
ToppCellBasal_cells|World / lung cells shred on cell class, cell subclass, sample id

CFH CELSR2 ARHGAP23 DLK2 LAMA5

4.71e-0519789524360b660000bdfb999d58fbf4e29585a97e1785
ToppCellBronchial-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SEMA5B C11orf96 SLIT3 ADCY5 RYR2

4.71e-05197895d1cb30ec4f3024541e9876c70bf63fe4d5c55bf1
ToppCellCOVID-19-lung-Fibroblast|COVID-19 / Disease (COVID-19 only), tissue and cell type

CFH NKD1 SLIT3 MMP14 RYR2

4.83e-051988953ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

C11orf96 CHRD LAMA5 ADCY5 RYR2

4.83e-051988957dd874b09c81cc512ccc1e9b65f290a5f94d736e
ToppCellcellseq-Mesenchymal-Myocytic-Myocytic_2|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NKD1 C11orf96 SLIT3 CHRD ADCY5

4.83e-05198895c7075dce915ab8387309fcb12c5f6a17d4100cda
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SEMA5B C11orf96 LAMA3 CHRD GGT5

4.83e-05198895b7e900fc0a1b3fa5e47dcc36ce6b0c3ce6bf9739
ToppCelltumor_Lung-Fibroblasts-COL14A1+_matrix_FBs|tumor_Lung / Location, Cell class and cell subclass

CFH C11orf96 SLIT3 MMP14 GGT5

4.83e-0519889574f2c7ef702b25a5b99e56121229e678ed992524
ToppCellcellseq-Mesenchymal-Myocytic-Myocytic_2-VSMC|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NKD1 C11orf96 SLIT3 CHRD ADCY5

4.83e-05198895e967c601101361fc1c48dab0e5b76dc68813276e
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Perivascular_fibroblast|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CFH C11orf96 SLIT3 MESP2 GGT5

4.94e-05199895dfc5c7a4a093baa7158dd8d4d29a870d9c469a3f
ToppCellBronchial-10x5prime-Stromal-Fibroblastic-Fibro_immune_recruiting|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CFH SLIT3 LAMA3 ADCY5 GGT5

4.94e-051998950cdbedf09ec72734b86ddab3fec562e066afed92
ToppCell10x5'v1-week_14-16-Mesenchymal_adipo-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

CFH SLIT3 PLEKHS1 MMP14 GGT5

4.94e-051998959b2262edbdec89166d895ab97527e0ee5f9b6010
ToppCellTracheal-10x5prime-Stromal-Myofibroblastic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

NKD1 C11orf96 SLIT3 ADCY5 RYR2

4.94e-051998950a145172787f40d0fdaf21188d539ffaf7ece3e4
ToppCell10x5'v1-week_14-16-Mesenchymal_adipo|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

CFH SLIT3 PLEKHS1 MMP14 GGT5

4.94e-05199895251b3643dcd8f4645b17101bd716e66f12a20e88
ToppCellParenchymal-10x5prime-Stromal-Myofibroblastic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

NKD1 C11orf96 SLIT3 CHRD ADCY5

4.94e-0519989520f760d92c351a1dac4cc0a424c443ea03a179fe
ToppCellBiopsy_IPF-Mesenchymal-Smooth_Muscle_cells|Biopsy_IPF / Sample group, Lineage and Cell type

NKD1 C11orf96 SLIT3 CHRD ADCY5

4.94e-05199895ffb871dc3d232a7bdc2d55d91b76e79883e8fa1b
ToppCellBronchial-10x5prime-Stromal-Myofibroblastic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

NKD1 C11orf96 SLIT3 ADCY5 RYR2

4.94e-05199895ad75e5e26c37a97331164d7f77235ebd9a933a44
ToppCellParenchymal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

NKD1 C11orf96 SLIT3 CHRD ADCY5

4.94e-051998957c272a1aa7f3e931ad5d20809719d85b3bce4cb0
ToppCellParenchyma_COVID-19-Stromal-TX-Smooth_muscle-2|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

NKD1 C11orf96 SLIT3 CHRD ADCY5

4.94e-05199895c8bc05dece8b8a87d4a7a3e8112b924e15217de1
ToppCellLung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Smooth_muscle-2-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NKD1 C11orf96 SLIT3 CHRD ADCY5

4.94e-0519989578b245d40c1e169ff2d26907b63d732e34529c5f
ToppCell10x5'v1-week_14-16-Mesenchymal_adipo-stroma-adipo-CAR|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

CFH SLIT3 PLEKHS1 MMP14 GGT5

4.94e-05199895117f4f43b6c06dda553799b1063e827bce697370
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Perivascular_fibroblast-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CFH C11orf96 SLIT3 MESP2 GGT5

4.94e-05199895c1760581c34b81d1d92c67500a1c8944e9cc6dad
ToppCellLung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Smooth_muscle-2|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

NKD1 C11orf96 SLIT3 CHRD ADCY5

4.94e-051998958e1e95c3a4b856415af208be6ad977e575bac189
ToppCellParenchymal-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ZNF512B ZNF517 SLIT3 VSIG10L CHRD

5.06e-0520089536de49593cf6ff1c9229fcceb150c1d68658a360
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NKD1 C11orf96 SLIT3 ADCY5 RYR2

5.06e-05200895a66449b22b39dd6987fc2c3ed160d24564234ced
Diseasen-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase measurement

CFH NAGPA

8.40e-062862EFO_0801816
Diseasecongenital myopathy 1A (implicated_via_orthology)

RYR2 RYR3

2.51e-053862DOID:3529 (implicated_via_orthology)
Diseasemalignant hyperthermia (implicated_via_orthology)

RYR2 RYR3

2.51e-053862DOID:8545 (implicated_via_orthology)
DiseaseNight blindness, congenital stationary, type 1

CACNA1F GPR179

5.44e-0412862C3501847
DiseaseNight Blindness, Congenital Stationary, Type 1A

CACNA1F GPR179

5.44e-0412862C3495587
DiseaseNIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 2B (disorder)

CACNA1F GPR179

5.44e-0412862C1864877
DiseaseNIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 1B

CACNA1F GPR179

5.44e-0412862C1850362
DiseaseX-Linked Csnb

CACNA1F GPR179

5.44e-0412862C3711543
DiseaseNIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 2A

CACNA1F GPR179

5.44e-0412862C1848172
DiseaseCone-rod synaptic disorder, congenital nonprogressive

CACNA1F GPR179

6.41e-0413862C4041558
DiseaseNight blindness, congenital stationary

CACNA1F GPR179

1.11e-0317862C0339535
Diseaseesophagus squamous cell carcinoma (is_marker_for)

KMT2D MMP14 TERT

1.33e-0374863DOID:3748 (is_marker_for)
Diseasepulmonary hypertension (biomarker_via_orthology)

TERT RYR2 RYR3

1.67e-0380863DOID:6432 (biomarker_via_orthology)
Diseasebeta-aminoisobutyric acid measurement

AGXT2 FBN3

2.22e-0324862EFO_0010464
Diseaselung squamous cell carcinoma (is_implicated_in)

KMT2D TERT

2.22e-0324862DOID:3907 (is_implicated_in)
Diseasebirth weight, parental genotype effect measurement

ZNF512B NFILZ ADCY5 RAI1

2.43e-03192864EFO_0004344, EFO_0005939

Protein segments in the cluster

PeptideGeneStartEntry
VFRGPWGGSHCRDSP

AGXT2

231

Q9BYV1
RSCGKGDPADRPWAG

CCDC187

1011

A0A096LP49
CLALGEEWGPRGGPS

CCDC85B

141

Q15834
PAAGEAGGSCLRWEP

APCDD1L

21

Q8NCL9
RGDAVCTESGWRPLP

CFH

246

P08603
APEGCPWSCRLLGIG

CELSR2

106

Q9HCU4
APRGGPEHRSAWGEA

ADCY5

21

O95622
CSKRPGEGWGDPCEL

FBN3

2041

Q75N90
ALRDWMGCPSGGRPD

MMP14

501

P50281
PEPRSSDGLGVGRAW

NXPH4

51

O95158
EWIGRQRCPGGVSGP

NKD1

36

Q969G9
LGDACPRWGLHPGEL

RAI1

751

Q7Z5J4
EGHVGSRPELRPCWG

NFILZ

201

A0A5F9ZHS7
CGPRDLGWEPAVERD

RASSF1

106

Q9NS23
ALWRREPVDPAGGSG

ADAMTS19

41

Q8TE59
CVGGRGASVPWDFLP

NPAS1

16

Q99742
FPGRGGVWRVVCRDP

PNMA8A

86

Q86V59
QTECRGRWPGPNGGI

CACNA1F

296

O60840
GWTGIRCDSTCPPGR

MEGF11

556

A6BM72
RDGDRWRSASPDGGP

GIGYF1

221

O75420
WATATCGERGPGEGR

LAMA3

61

Q16787
RTQCEHPCWEGGRGP

INKA2

71

Q9NTI7
CPWESADRGGLSPGS

GPR179

1321

Q6PRD1
PPGGWAVARLEGREF

FOXK2

31

Q01167
RQRGDAGSPWGCPLC

MESP2

151

Q0VG99
GCIEPGPGHWGELSR

CCDC97

16

Q96F63
WLEAVFGTPRRAGCP

PDCD7

146

Q8N8D1
PAAGCVRGERPGWAA

PINK1

36

Q9BXM7
KARGRGCHCPGDAPW

RIPPLY3

11

P57055
LPRACWEGRITAGSP

LRRC74A

11

Q0VAA2
RCPEPDARHGWGSGS

LCA10

71

Q71F78
TGPRGAGRPCLFWDQ

KREMEN2

51

Q8NCW0
GFWGLSPSNPEGCTR

LAMA5

761

O15230
LPRAGGWAVPRGCDP

PSMB11

21

A5LHX3
CGSPPRGWSEELDER

ARHGAP12

336

Q8IWW6
ASLGPEWSQEGCRPG

FAM182B

126

Q5T319
FSCGGWIRRNPLPDG

EEF1AKMT4-ECE2

241

P0DPD8
GALSTSIPWGCRDPG

CEFIP

341

Q711Q0
ALSDSPDGRPGGFWR

KCNC1

156

P48547
QLPCGEGRPGWVRGE

COLCA1

41

Q6ZS62
REAAGTGWDPGASPR

FAM241A

26

Q8N8J7
RVEPFLRPEWSGTGG

COX11

31

Q9Y6N1
ACNEVERAPARGPGW

CPAMD8

1676

Q8IZJ3
PGGRPPRADAKCWFA

GUCY2F

441

P51841
VSGDRVGGAPGRCWP

GGT5

446

P36269
CSPDGEWRRLGRPVF

IDUA

481

P35475
GGGPSAWEACPPALR

MAP3K12

581

Q12852
APREDGGARGVWLPS

IFRD2

16

Q12894
GTGTRLAPWPGRACG

ME3

6

Q16798
APDGSCRCDPGWEGL

DLK2

41

Q6UY11
GGEPRTDCTISWGGP

ETV2

171

O00321
GDMRVGWSRPGCQPD

RYR2

1111

Q92736
RDCGVAATGLPPRVW

NEURL4

176

Q96JN8
RWSAALPCAEARGPG

TRMT44

46

Q8IYL2
GASCSWQRPPGERGS

TMEM200C

396

A6NKL6
GLWPGRPCSAGREVD

KCP

1381

Q6ZWJ8
SSVWGPPDACRGDLR

MIIP

71

Q5JXC2
FWRGPGCDELDCGPS

NAGPA

351

Q9UK23
RACLEPGGLGPRTEW

SWSAP1

181

Q6NVH7
EEPPSEGPGSCLRRW

NUAK2

581

Q9H093
LPVRCAGDWLPRGLG

ALG2

66

Q9H553
ACEAPQWGRRTRGPG

CHRD

81

Q9H2X0
DLRPRGQPGWCRLGD

C11orf96

106

Q7Z7L8
GQPGWCRLGDPRRDS

C11orf96

111

Q7Z7L8
RPGWTGPLCDQEARD

SLIT3

1356

O75094
GRICVSQWEGPPRLG

PLEKHS1

341

Q5SXH7
WAPGGDLEGCAPDTR

RNF149

81

Q8NC42
FSEPGVWGPRPCRVG

RP1L1

376

Q8IWN7
SEWGGRPQGCPGKAR

RP1L1

546

Q8IWN7
ADPEGPEGGCSLAWR

SLC27A3

56

Q5K4L6
VGWARPGCRPDVELG

RYR3

1101

Q15413
GPAEEGAREPGWCKT

SOX12

21

O15370
DGETLRPGLCALWDP

PLEKHG4B

666

Q96PX9
GPGALVSPRFERCGW

ARHGAP23

366

Q9P227
ASPRGDPGLGERDWT

TNKS1BP1

761

Q9C0C2
PGGGTERPCASAWQL

TMEM102

351

Q8N9M5
GPRPAGEWEGDRAEA

ZBTB4

206

Q9P1Z0
ARWRGPAGPEGTEDV

PPP1R3D

221

O95685
SWLGCPEEGALRVRG

SCART1

776

Q4G0T1
CPVRNVTRDGGFGPW

SEMA5B

601

Q9P283
REPGEDTEGRRAPCW

ZNF517

476

Q6ZMY9
PGRSELVEGCGWRCP

TRIM14

11

Q14142
DWPPGCRDKGARGST

ZNF512B

866

Q96KM6
PGHGTQGWEPCTDLR

TSPEAR

16

Q8WU66
PGDRSLRFRCSWPGG

VSIG10L

506

Q86VR7
GEAWLECSLRGGTPP

VSIG10L2

516

P0DP72
ERPRGDAGAEWEPLG

ZNF71

46

Q9NQZ8
DCAWLRRSPGVGCVP

TERT

516

O14746
GVRIPPSGWKCARCD

USP13

201

Q92995
TCRVAGGPGTPRLAW

TMEM25

51

Q86YD3
SPGPGSGGERWCAEV

WDR73

216

Q6P4I2
ERGETPWCSVPRGAL

ZNF662

26

Q6ZS27
GEEAPRFPHLGSGRW

KMT2D

4716

O14686