Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	methionine adenosyltransferase activity	MAT1A MAT2A	4.54e-05	2	135	2	GO:0004478
GeneOntologyMolecularFunction	bile acid transmembrane transporter activity	PSG1 SLCO1B3 SLCO1B1 SLCO1B7	7.92e-05	34	135	4	GO:0015125
GeneOntologyMolecularFunction	prostaglandin transmembrane transporter activity	SLCO1B3 SLCO1B1 SLCO1B7	1.04e-04	14	135	3	GO:0015132
GeneOntologyMolecularFunction	icosanoid transmembrane transporter activity	SLCO1B3 SLCO1B1 SLCO1B7	1.30e-04	15	135	3	GO:0071714
GeneOntologyMolecularFunction	oligopeptide transmembrane transporter activity	SLCO1B3 SLCO1B1 SLCO1B7	1.59e-04	16	135	3	GO:0035673
GeneOntologyMolecularFunction	sodium-independent organic anion transmembrane transporter activity	SLCO1B3 SLCO1B1 SLCO1B7	2.29e-04	18	135	3	GO:0015347
GeneOntologyMolecularFunction	lipid transporter activity	NPC1 PSG1 ABCA13 SLCO1B3 SLCO1B1 ATP8B2 SLCO1B7	3.79e-04	196	135	7	GO:0005319
GeneOntologyMolecularFunction	alkylglycerophosphoethanolamine phosphodiesterase activity	GNA11 GNAQ	4.48e-04	5	135	2	GO:0047391
GeneOntologyMolecularFunction	inhibin binding	ACVR2B IGSF1	4.48e-04	5	135	2	GO:0034711
GeneOntologyBiologicalProcess	central nervous system neuron development	ARHGEF28 OGDH ADARB1 SLIT2 PALS1 PAFAH1B1 GNAQ	3.25e-06	99	131	7	GO:0021954
GeneOntologyBiologicalProcess	regulation of melanocyte differentiation	ADAMTS20 GNA11 GNAQ	8.60e-06	7	131	3	GO:0045634
GeneOntologyBiologicalProcess	protein complex oligomerization	TRPM6 MAT1A MAT2A ALS2 SLC1A2 IKZF4 APPL2 TRPM3 CARD9 TRPM1	1.99e-05	296	131	10	GO:0051259
GeneOntologyBiologicalProcess	regulation of pigment cell differentiation	ADAMTS20 GNA11 GNAQ	2.05e-05	9	131	3	GO:0050932
GeneOntologyBiologicalProcess	trans-synaptic signaling by trans-synaptic complex	TENM2 CADM1 IL1RAP	3.98e-05	11	131	3	GO:0099545
GeneOntologyBiologicalProcess	sodium-independent organic anion transport	SLCO1B3 SLCO1B1 SLCO1B7	1.08e-04	15	131	3	GO:0043252
GeneOntologyCellularComponent	cuticular plate	CALB1 SPTA1 SPTAN1	8.01e-05	13	140	3	GO:0032437
GeneOntologyCellularComponent	methionine adenosyltransferase complex	MAT1A MAT2A	1.33e-04	3	140	2	GO:0048269
Domain	TRPM_tetra	TRPM6 TRPM3 TRPM1	1.44e-06	4	134	3	PF16519
Domain	TRPM_tetra	TRPM6 TRPM3 TRPM1	1.44e-06	4	134	3	IPR032415
Domain	S-AdoMet_synt_N	MAT1A MAT2A	5.11e-05	2	134	2	PF00438
Domain	S-AdoMet_synthetase	MAT1A MAT2A	5.11e-05	2	134	2	IPR002133
Domain	S-AdoMet_synt_M	MAT1A MAT2A	5.11e-05	2	134	2	PF02772
Domain	S-AdoMet_synt_C	MAT1A MAT2A	5.11e-05	2	134	2	PF02773
Domain	ADOMET_SYNTHASE_CS	MAT1A MAT2A	5.11e-05	2	134	2	IPR022631
Domain	S-AdoMet_synt_C	MAT1A MAT2A	5.11e-05	2	134	2	IPR022630
Domain	S-AdoMet_synthetase_sfam	MAT1A MAT2A	5.11e-05	2	134	2	IPR022636
Domain	S-AdoMet_synt_central	MAT1A MAT2A	5.11e-05	2	134	2	IPR022629
Domain	S-AdoMet_synt_N	MAT1A MAT2A	5.11e-05	2	134	2	IPR022628
Domain	ADOMET_SYNTHASE_1	MAT1A MAT2A	5.11e-05	2	134	2	PS00376
Domain	ADOMET_SYNTHASE_2	MAT1A MAT2A	5.11e-05	2	134	2	PS00377
Domain	OA_transporter	SLCO1B3 SLCO1B1 SLCO1B7	7.58e-05	12	134	3	IPR004156
Domain	OATP	SLCO1B3 SLCO1B1 SLCO1B7	7.58e-05	12	134	3	PF03137
Domain	Gprotein_alpha_Q	GNA11 GNAQ	3.04e-04	4	134	2	IPR000654
Domain	RCC1	ALS2 RCC1L HERC5	3.76e-04	20	134	3	PF00415
Domain	RCC1_1	ALS2 RCC1L HERC5	4.37e-04	21	134	3	PS00625
Domain	RCC1_2	ALS2 RCC1L HERC5	4.37e-04	21	134	3	PS00626
Domain	RCC1_3	ALS2 RCC1L HERC5	4.37e-04	21	134	3	PS50012
Domain	-	ALS2 RCC1L HERC5	5.03e-04	22	134	3	2.130.10.30
Domain	Reg_chr_condens	ALS2 RCC1L HERC5	5.03e-04	22	134	3	IPR000408
Domain	Spectrin	SPTA1 SPTAN1 DST	5.76e-04	23	134	3	PF00435
Domain	RCC1/BLIP-II	ALS2 RCC1L HERC5	5.76e-04	23	134	3	IPR009091
Domain	PQQ	ERN2 WDR86	7.52e-04	6	134	2	SM00564
Domain	EFhand_Ca_insen	SPTA1 SPTAN1	7.52e-04	6	134	2	PF08726
Domain	EF-hand_Ca_insen	SPTA1 SPTAN1	7.52e-04	6	134	2	IPR014837
Domain	PQQ_beta_propeller_repeat	ERN2 WDR86	7.52e-04	6	134	2	IPR018391
Domain	Spectrin_repeat	SPTA1 SPTAN1 DST	1.15e-03	29	134	3	IPR002017
Domain	Ion_trans_dom	TRPM6 TRPM3 SCN7A TRPM1 MCOLN2	1.39e-03	114	134	5	IPR005821
Domain	Ion_trans	TRPM6 TRPM3 SCN7A TRPM1 MCOLN2	1.39e-03	114	134	5	PF00520
Domain	SPEC	SPTA1 SPTAN1 DST	1.54e-03	32	134	3	SM00150
Domain	Spectrin/alpha-actinin	SPTA1 SPTAN1 DST	1.54e-03	32	134	3	IPR018159
Pathway	REACTOME_TRP_CHANNELS	TRPM6 TRPM3 TRPM1 MCOLN2	3.22e-05	28	93	4	MM14943
Pathway	REACTOME_TRP_CHANNELS	TRPM6 TRPM3 TRPM1 MCOLN2	3.22e-05	28	93	4	M27241
Pathway	REACTOME_TRANSPORT_OF_ORGANIC_ANIONS	SLCO1B3 SLCO1B1 SLCO1B7	5.86e-05	12	93	3	MM15476
Pathway	REACTOME_ATORVASTATIN_ADME	SLCO1B3 SLCO1B1 SLCO1B7	1.19e-04	15	93	3	MM15697
Pubmed	A novel gene family NBPF: intricate structure generated by gene duplications during primate evolution.	NBPF8 NBPF12 NBPF20 NBPF19 NBPF9 NBPF10 NBPF14	1.72e-12	21	141	7	16079250
Pubmed	New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.	NBPF8 PRPF31 NBPF12 ILF3 ABCA13 SPTAN1 CSMD3 STRIP2 DST NBPF9 NBPF10 ADAMTS20 IGSF1 NBPF14	2.53e-08	513	141	14	25798074
Pubmed	Large-scale proteomics and phosphoproteomics of urinary exosomes.	NPC1 CALB1 UACA VPS13C GBE1 DDX3X SH3BP4 BROX SLIT2 PALS1 FAT1 APPL2 PAFAH1B1 FTH1 CCT8 GNA11 GNAQ DYNC1H1 MASP2	3.27e-08	1016	141	19	19056867
Pubmed	Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?	NBPF8 NBPF12 SLIT2 FAT1 CDH22 MDN1 NBPF9 NBPF10 NBPF14	3.47e-08	170	141	9	23314748
Pubmed	Evolutionary history and genome organization of DUF1220 protein domains.	NBPF8 NBPF12 NBPF9 NBPF14	5.33e-08	10	141	4	22973535
Pubmed	Characterization of organic anion transporting polypeptide 1b2-null mice: essential role in hepatic uptake/toxicity of phalloidin and microcystin-LR.	SLCO1B3 SLCO1B1 SLCO1B7	6.52e-08	3	141	3	18296417
Pubmed	Role of the murine organic anion-transporting polypeptide 1b2 (Oatp1b2) in drug disposition and hepatotoxicity.	SLCO1B3 SLCO1B1 SLCO1B7	6.52e-08	3	141	3	18492796
Pubmed	Differential Expression of OATP1B3 Mediates Unconjugated Testosterone Influx.	SLCO1B3 SLCO1B1 SLCO1B7	6.52e-08	3	141	3	28389619
Pubmed	Organic anion transporting polypeptide 1B transporters modulate hydroxyurea pharmacokinetics.	SLCO1B3 SLCO1B1 SLCO1B7	6.52e-08	3	141	3	23986199
Pubmed	Organic anion-transporting polypeptide 1b2 (Oatp1b2) is important for the hepatic uptake of unconjugated bile acids: Studies in Oatp1b2-null mice.	SLCO1B3 SLCO1B1 SLCO1B7	6.52e-08	3	141	3	20949553
Pubmed	Synergistic interaction between genetics and disease on pravastatin disposition.	SLCO1B3 SLCO1B1 SLCO1B7	6.52e-08	3	141	3	24613363
Pubmed	Full-length cDNA cloning and genomic organization of the mouse liver-specific organic anion transporter-1 (lst-1).	SLCO1B3 SLCO1B1 SLCO1B7	6.52e-08	3	141	3	10833452
Pubmed	Interaction Between Sex and Organic Anion-Transporting Polypeptide 1b2 on the Pharmacokinetics of Regorafenib and Its Metabolites Regorafenib-N-Oxide and Regorafenib-Glucuronide in Mice.	SLCO1B3 SLCO1B1 SLCO1B7	6.52e-08	3	141	3	30955241
Pubmed	Influence of drug formulation on OATP1B-mediated transport of paclitaxel.	SLCO1B3 SLCO1B1 SLCO1B7	6.52e-08	3	141	3	24755470
Pubmed	OATP1B2 deficiency protects against paclitaxel-induced neurotoxicity.	SLCO1B3 SLCO1B1 SLCO1B7	6.52e-08	3	141	3	29337310
Pubmed	Expression of Oatp2 in the Brain and Liver of Alzheimer Disease Mouse Model.	SLCO1B3 SLCO1B1 SLCO1B7	6.52e-08	3	141	3	31967785
Pubmed	Targeted disruption of murine organic anion-transporting polypeptide 1b2 (Oatp1b2/Slco1b2) significantly alters disposition of prototypical drug substrates pravastatin and rifampin.	SLCO1B3 SLCO1B1 SLCO1B7	6.52e-08	3	141	3	18413659
Pubmed	Identification, expression, and functional characterization of full-length and splice variants of murine organic anion transporting polypeptide 1b2.	SLCO1B3 SLCO1B1 SLCO1B7	6.52e-08	3	141	3	19400585
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	KRT8 UAP1 ILF3 SPTA1 SPTAN1 MUC19 RICTOR FYCO1 OGDH DDX3X DST MDN1 CCT8 PCNX1 NNT DYNC1H1	1.98e-07	807	141	16	30575818
Pubmed	Impact of Oatp1c1 deficiency on thyroid hormone metabolism and action in the mouse brain.	SLCO1B3 SLCO1B1 SLCO1B7	2.60e-07	4	141	3	22294745
Pubmed	Organic anion transporting polypeptide 1a/1b-knockout mice provide insights into hepatic handling of bilirubin, bile acids, and drugs.	SLCO1B3 SLCO1B1 SLCO1B7	2.60e-07	4	141	3	20644253
Pubmed	Protection against phalloidin-induced liver injury by oleanolic acid involves Nrf2 activation and suppression of Oatp1b2.	SLCO1B3 SLCO1B1 SLCO1B7	2.60e-07	4	141	3	25280775
Pubmed	Contribution of Organic Anion-Transporting Polypeptides 1A/1B to Doxorubicin Uptake and Clearance.	SLCO1B3 SLCO1B1 SLCO1B7	2.60e-07	4	141	3	27777271
Pubmed	Network organization of the huntingtin proteomic interactome in mammalian brain.	CALB1 SPTA1 SPTAN1 OGDH SLC1A2 ADAM22 DDX3X PHF2 DST CCT8 ADAMTS20 GNA11 GNAQ DYNC1H1	2.62e-07	621	141	14	22794259
Pubmed	OATP1A/1B transporters affect irinotecan and SN-38 pharmacokinetics and carboxylesterase expression in knockout and humanized transgenic mice.	SLCO1B3 SLCO1B1 SLCO1B7	6.48e-07	5	141	3	24194565
Pubmed	Complete OATP1B1 and OATP1B3 deficiency causes human Rotor syndrome by interrupting conjugated bilirubin reuptake into the liver.	SLCO1B3 SLCO1B1 SLCO1B7	1.29e-06	6	141	3	22232210
Pubmed	Analysis of DNA methylation and histone modification profiles of liver-specific transporters.	SLCO1B3 SLCO1B1 SLCO1B7	1.29e-06	6	141	3	19047482
Pubmed	LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.	ILF3 MAT2A SPTAN1 GBE1 OGDH PHKB MDN1 CCT8 NNT DYNC1H1	1.54e-06	344	141	10	30333137
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	ILF3 UACA SPTAN1 FYCO1 SLC1A2 TENM2 PREPL ADAM22 DDX3X PALS1 DST MDN1 SVIL CCT8 NEURL4 DYNC1H1	2.01e-06	963	141	16	28671696
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	PRPF31 KRT8 UAP1 ARHGEF28 SPTAN1 RICTOR ALS2 DDX3X SH3BP4 DST MDN1 PIK3C2B CASKIN2 SVIL CDC25B	2.42e-06	861	141	15	36931259
Pubmed	International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels.	TRPM6 TRPM3 TRPM1 MCOLN2	3.06e-06	25	141	4	16382100
Pubmed	An introduction to TRP channels.	TRPM6 TRPM3 TRPM1 MCOLN2	4.23e-06	27	141	4	16460286
Pubmed	STING-Mediated IFI16 Degradation Negatively Controls Type I Interferon Production.	PRPF31 ILF3 MAT2A SPTAN1 DDX3X LIG3 CCT8 POLR1B HERC5	6.17e-06	316	141	9	31665637
Pubmed	Critical role of PPAR-alpha in perfluorooctanoic acid- and perfluorodecanoic acid-induced downregulation of Oatp uptake transporters in mouse livers.	SLCO1B3 SLCO1B1 SLCO1B7	7.67e-06	10	141	3	18703564
Pubmed	A quantitative analysis of the spatiotemporal pattern of transient receptor potential gene expression in the developing mouse cochlea.	TRPM6 TRPM3 TRPM1 MCOLN2	9.67e-06	33	141	4	19834762
Pubmed	Exchangeable gene trap using the Cre/mutated lox system.	NRIP1 TCF3 MAT2A SH3BP4 BROX RCC1L CADM1 SVIL POLR1B RERE KLHL8	1.32e-05	538	141	11	10512203
Pubmed	Faciogenital Dysplasia 5 supports cancer stem cell traits in basal-like breast cancer by enhancing EGFR stability.	KRT8 UACA SPTAN1 DST SVIL CCT8 DYNC1H1	1.37e-05	191	141	7	33762435
Pubmed	Dynamic expression of the TRPM subgroup of ion channels in developing mouse sensory neurons.	TRPM6 TRPM3 TRPM1	1.40e-05	12	141	3	19850157
Pubmed	The Role of Mutation Rates of GNAQ or GNA11 in Cases of Uveal Melanoma in Japan.	GNA11 GNAQ	1.63e-05	2	141	2	28248732
Pubmed	Activation of Gq/11 in the mouse corpus luteum is required for parturition.	GNA11 GNAQ	1.63e-05	2	141	2	25495873
Pubmed	Modulation of transporter activity of OATP1B1 and OATP1B3 by the major active components of Radix Ophiopogonis.	SLCO1B3 SLCO1B1	1.63e-05	2	141	2	29944058
Pubmed	SLCO1B1 and SLCO1B3 genetic mutations in Taiwanese patients with Rotor syndrome.	SLCO1B3 SLCO1B1	1.63e-05	2	141	2	36964102
Pubmed	Role of transcriptional and posttranscriptional regulation of methionine adenosyltransferases in liver cancer progression.	MAT1A MAT2A	1.63e-05	2	141	2	22318685
Pubmed	Molecular genetic testing of uveal melanoma from routinely processed and stained cytology specimens.	GNA11 GNAQ	1.63e-05	2	141	2	21945171
Pubmed	Interaction of the G-protein G11alpha with receptors and phosphoinositidase C: the contribution of G-protein palmitoylation and membrane association.	GNA11 GNAQ	1.63e-05	2	141	2	9175863
Pubmed	Contribution of OATP1B1 and OATP1B3 to the disposition of sorafenib and sorafenib-glucuronide.	SLCO1B3 SLCO1B1	1.63e-05	2	141	2	23340295
Pubmed	Further Studies to Support the Use of Coproporphyrin I and III as Novel Clinical Biomarkers for Evaluating the Potential for Organic Anion Transporting Polypeptide 1B1 and OATP1B3 Inhibition.	SLCO1B3 SLCO1B1	1.63e-05	2	141	2	29777022
Pubmed	Down-regulation of OATP1B proteins correlates with hyperbilirubinemia in advanced cholestasis.	SLCO1B3 SLCO1B1	1.63e-05	2	141	2	26191226
Pubmed	The ethnic profile of patients with birthmarks reveals interaction of germline and postzygotic genetics.	GNA11 GNAQ	1.63e-05	2	141	2	28083870
Pubmed	Utility of Oatp1a/1b-knockout and OATP1B1/3-humanized mice in the study of OATP-mediated pharmacokinetics and tissue distribution: case studies with pravastatin, atorvastatin, simvastatin, and carboxydichlorofluorescein.	SLCO1B3 SLCO1B1	1.63e-05	2	141	2	24194513
Pubmed	Gq/11-Dependent Changes in the Murine Ovarian Transcriptome at the End of Gestation.	GNA11 GNAQ	1.63e-05	2	141	2	26843449
Pubmed	Direct targeting of Gαq and Gα11 oncoproteins in cancer cells.	GNA11 GNAQ	1.63e-05	2	141	2	30890659
Pubmed	Microtubule-binding-induced allostery triggers LIS1 dissociation from dynein prior to cargo transport.	PAFAH1B1 DYNC1H1	1.63e-05	2	141	2	37322240
Pubmed	A novel mechanism of the M1-M2 methionine adenosyltransferase switch-mediated hepatocellular carcinoma metastasis.	MAT1A MAT2A	1.63e-05	2	141	2	29749642
Pubmed	Evaluation of organic anion transporting polypeptide 1B1 and 1B3 humanized mice as a translational model to study the pharmacokinetics of statins.	SLCO1B3 SLCO1B1	1.63e-05	2	141	2	24855184
Pubmed	Gonadotropin and gonadal steroid release in response to a gonadotropin-releasing hormone agonist in Gqalpha and G11alpha knockout mice.	GNA11 GNAQ	1.63e-05	2	141	2	9607776
Pubmed	Nuclear factor 90 uses an ADAR2-like binding mode to recognize specific bases in dsRNA.	ILF3 ADARB1	1.63e-05	2	141	2	26712564
Pubmed	Preclinical Mouse Models To Study Human OATP1B1- and OATP1B3-Mediated Drug-Drug Interactions in Vivo.	SLCO1B3 SLCO1B1	1.63e-05	2	141	2	26474710
Pubmed	Effects of anthocyans on the expression of organic anion transporting polypeptides (SLCOs/OATPs) in primary human hepatocytes.	SLCO1B3 SLCO1B1	1.63e-05	2	141	2	25578040
Pubmed	Reverse Phenotyping in Patients with Skin Capillary Malformations and Mosaic GNAQ or GNA11 Mutations Defines a Clinical Spectrum with Genotype-Phenotype Correlation.	GNA11 GNAQ	1.63e-05	2	141	2	31726051
Pubmed	G(alpha)q-deficient mice lack metabotropic glutamate receptor-dependent long-term depression but show normal long-term potentiation in the hippocampal CA1 region.	GNA11 GNAQ	1.63e-05	2	141	2	11438569
Pubmed	GNAQ/GNA11 Mosaicism Is Associated with Abnormal Serum Calcium Indices and Microvascular Neurocalcification.	GNA11 GNAQ	1.63e-05	2	141	2	37802294
Pubmed	Prediction of organic anion-transporting polypeptide 1B1- and 1B3-mediated hepatic uptake of statins based on transporter protein expression and activity data.	SLCO1B3 SLCO1B1	1.63e-05	2	141	2	24989890
Pubmed	Distinct profiles of functional discrimination among G proteins determine the actions of G protein-coupled receptors.	GNA11 GNAQ	1.63e-05	2	141	2	26628681
Pubmed	The time-course of agonist-induced solubilization of trimeric G(q)alpha/G(11)alpha proteins resolved by two-dimensional electrophoresis.	GNA11 GNAQ	1.63e-05	2	141	2	17552882
Pubmed	αII-spectrin regulates invadosome stability and extracellular matrix degradation.	SPTA1 SPTAN1	1.63e-05	2	141	2	25830635
Pubmed	Heterogeneity in Mitogen-Activated Protein Kinase (MAPK) Pathway Activation in Uveal Melanoma With Somatic GNAQ and GNA11 Mutations.	GNA11 GNAQ	1.63e-05	2	141	2	31173078
Pubmed	Expression of organic anion-transporting polypeptides 1B1 and 1B3 in ovarian cancer cells: relevance for paclitaxel transport.	SLCO1B3 SLCO1B1	1.63e-05	2	141	2	21719246
Pubmed	Organic anion transporting polypeptide 1B1 (OATP1B1) and OATP1B3: genetic variability and haplotype analysis in white Canadians.	SLCO1B3 SLCO1B1	1.63e-05	2	141	2	20877131
Pubmed	Frequent and Yet Unreported GNAQ and GNA11 Mutations are Found in Uveal Melanomas.	GNA11 GNAQ	1.63e-05	2	141	2	29209985
Pubmed	Alterations of Methionine Metabolism as Potential Targets for the Prevention and Therapy of Hepatocellular Carcinoma.	MAT1A MAT2A	1.63e-05	2	141	2	31234428
Pubmed	Histological expression of methionine adenosyl transferase (MAT) 2A as a post-surgical prognostic surrogate in patients with hepatocellular carcinoma.	MAT1A MAT2A	1.63e-05	2	141	2	29448301
Pubmed	Transport of fluorescent chenodeoxycholic acid via the human organic anion transporters OATP1B1 and OATP1B3.	SLCO1B3 SLCO1B1	1.63e-05	2	141	2	16534140
Pubmed	Effect of pregnane X receptor ligands on transport mediated by human OATP1B1 and OATP1B3.	SLCO1B3 SLCO1B1	1.63e-05	2	141	2	18321482
Pubmed	Distinct roles of Galpha(q) and Galpha11 for Purkinje cell signaling and motor behavior.	GNA11 GNAQ	1.63e-05	2	141	2	15175381
Pubmed	Trans-homophilic interaction of CADM1 promotes organ infiltration of T-cell lymphoma by adhesion to vascular endothelium.	CADM4 CADM1	1.63e-05	2	141	2	35213073
Pubmed	Oncogenic GNAQ and GNA11 mutations in uveal melanoma in Chinese.	GNA11 GNAQ	1.63e-05	2	141	2	25280020
Pubmed	GNAQ and GNA11 mutations occur in 9.5% of mucosal melanoma and are associated with poor prognosis.	GNA11 GNAQ	1.63e-05	2	141	2	27498141
Pubmed	Interaction of oral antidiabetic drugs with hepatic uptake transporters: focus on organic anion transporting polypeptides and organic cation transporter 1.	SLCO1B3 SLCO1B1	1.63e-05	2	141	2	18314419
Pubmed	Transient receptor potential melastatin 1 (TRPM1) is an ion-conducting plasma membrane channel inhibited by zinc ions.	TRPM3 TRPM1	1.63e-05	2	141	2	21278253
Pubmed	OATP 1B1/1B3 expression in hepatocellular carcinomas treated with orthotopic liver transplantation.	SLCO1B3 SLCO1B1	1.63e-05	2	141	2	21691816
Pubmed	Uveal Melanoma: GNAQ and GNA11 Mutations in a Greek Population.	GNA11 GNAQ	1.63e-05	2	141	2	28982892
Pubmed	Mutations in GNA11 in uveal melanoma.	GNA11 GNAQ	1.63e-05	2	141	2	21083380
Pubmed	Selective NADH communication from α-ketoglutarate dehydrogenase to mitochondrial transhydrogenase prevents reactive oxygen species formation under reducing conditions in the heart.	OGDH NNT	1.63e-05	2	141	2	32748289
Pubmed	GNAQ and GNA11 mutations in uveal melanoma.	GNA11 GNAQ	1.63e-05	2	141	2	25304237
Pubmed	Structures of human dynein in complex with the lissencephaly 1 protein, LIS1.	PAFAH1B1 DYNC1H1	1.63e-05	2	141	2	36692009
Pubmed	Epidermal loss of Gαq confers a migratory and differentiation defect in keratinocytes.	GNA11 GNAQ	1.63e-05	2	141	2	28301547
Pubmed	Forebrain-specific inactivation of Gq/G11 family G proteins results in age-dependent epilepsy and impaired endocannabinoid formation.	GNA11 GNAQ	1.63e-05	2	141	2	16847339
Pubmed	Linking organic anion transporting polypeptide 1B1 and 1B3 (OATP1B1 and OATP1B3) interaction profiles to hepatotoxicity - The hyperbilirubinemia use case.	SLCO1B3 SLCO1B1	1.63e-05	2	141	2	28063966
Pubmed	Uveal melanoma driver mutations in GNAQ/11 yield numerous changes in melanocyte biology.	GNA11 GNAQ	1.63e-05	2	141	2	29570931
Pubmed	Muscarinic inhibition of calcium current and M current in Galpha q-deficient mice.	GNA11 GNAQ	1.63e-05	2	141	2	10818132
Pubmed	LIS1 promotes the formation of activated cytoplasmic dynein-1 complexes.	PAFAH1B1 DYNC1H1	1.63e-05	2	141	2	32341549
Pubmed	Endothelial Gαq/11 is required for VEGF-induced vascular permeability and angiogenesis.	GNA11 GNAQ	1.63e-05	2	141	2	26272756
Pubmed	NK2 receptor-mediated detrusor muscle contraction involves Gq/11-dependent activation of voltage-dependent Ca2+ channels and the RhoA-Rho kinase pathway.	GNA11 GNAQ	1.63e-05	2	141	2	31461351
Pubmed	Ultradeep sequencing detects GNAQ and GNA11 mutations in cell-free DNA from plasma of patients with uveal melanoma.	GNA11 GNAQ	1.63e-05	2	141	2	23634288
Pubmed	Long-lasting inhibitory effects of cyclosporin A, but not tacrolimus, on OATP1B1- and OATP1B3-mediated uptake.	SLCO1B3 SLCO1B1	1.63e-05	2	141	2	22240838
Pubmed	Distribution of GNAQ and GNA11 Mutation Signatures in Uveal Melanoma Points to a Light Dependent Mutation Mechanism.	GNA11 GNAQ	1.63e-05	2	141	2	26368812
Pubmed	Postsynaptic mechanisms underlying responsiveness of amygdaloid neurons to cholecystokinin are mediated by a transient receptor potential-like current.	GNA11 GNAQ	1.63e-05	2	141	2	17482476
Pubmed	Human organic anion transporter 1B1 and 1B3 function as bidirectional carriers and do not mediate GSH-bile acid cotransport.	SLCO1B3 SLCO1B1	1.63e-05	2	141	2	17412826
Pubmed	Combined PKC and MEK inhibition in uveal melanoma with GNAQ and GNA11 mutations.	GNA11 GNAQ	1.63e-05	2	141	2	24141786
Cytoband	1q21.1	NBPF8 NBPF9 NBPF10 NBPF14	4.14e-05	62	141	4	1q21.1
Cytoband	Ensembl 112 genes in cytogenetic band chr1q21	NBPF12 ATP8B2 NBPF20 NBPF19 NBPF9 NBPF10 NBPF14	2.67e-04	404	141	7	chr1q21
GeneFamily	Neuroblastoma breakpoint family	NBPF8 NBPF12 NBPF26 NBPF20 NBPF19 NBPF9 NBPF10 NBPF14	2.15e-13	23	96	8	662
GeneFamily	Transient receptor potential cation channels	TRPM6 TRPM3 TRPM1 MCOLN2	1.39e-05	28	96	4	249
GeneFamily	EF-hand domain containing\|Spectrins	SPTA1 SPTAN1	5.76e-04	7	96	2	1113
GeneFamily	CD molecules\|Type II classical cadherins	CDH22 CDH7	2.09e-03	13	96	2	1186
Coexpression	GSE17721_CPG_VS_GARDIQUIMOD_2H_BMDC_UP	SPTAN1 GIMAP1 RSPRY1 SH3BP4 PALS1 MTMR14 NFKBIB IL1RAP	1.33e-05	200	141	8	M3881
Coexpression	GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN	NPC1 WSCD1 SLC22A23 HBP1 RICTOR FYCO1 ZFYVE1 SH3BP4 CADM1 DST APPL2 PAFAH1B1 SVIL NFKBIB PCNX1 SMPD2 TMEM151A ULK2	2.71e-05	1102	141	18	M2369
Coexpression	HARALAMBIEVA_PBMC_FLUARIX_AGE_50_74YO_CORR_WITH_28D_MEM_B_CELL_RESPONSE_AT_3DY_POSITIVE	NRIP1 GANC HBP1 DDX3X NBPF9 C11orf96 NBPF10 GNA11 GNAQ IL1RAP	3.19e-05	368	141	10	M41100
Coexpression	GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN	NPC1 WSCD1 SLC22A23 HBP1 RICTOR FYCO1 ZFYVE1 SH3BP4 CADM1 DST APPL2 PAFAH1B1 SVIL NFKBIB PCNX1 SMPD2 TMEM151A ULK2	3.51e-05	1124	141	18	MM1070
Coexpression	HOWARD_NEUTROPHIL_INACT_MONOV_INFLUENZA_A_INDONESIA_05_2005_H5N1_AGE_18_49YO_3DY_UP	PRPF31 GIMAP1 BTN3A3 MDN1 WDR86 HERC5	4.59e-05	119	141	6	M41109
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN	NRIP1 GBE1 RNF13 ADARB1 FAT1 DST MDN1 PAFAH1B1 TMEM131 GNAQ IL1RAP	4.61e-05	466	141	11	M13522
Coexpression	NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_DN	CALB1 LYZL4 SLC22A23 SLCO1B3 HBP1 FYCO1 CPE ADARB1 PHKB NDUFAF7 C11orf96 FTH1 RERE	5.00e-05	648	141	13	M14371
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX11 ATP13A4 ABCA13 SPTA1 SLC35F1 CSMD3 FAT1 TRPM3 ADAMTS20	7.27e-09	184	140	9	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX11 ATP13A4 ABCA13 SPTA1 SLC35F1 CSMD3 FAT1 TRPM3 ADAMTS20	7.27e-09	184	140	9	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX11 ATP13A4 ABCA13 SPTA1 SLC35F1 CSMD3 FAT1 TRPM3 ADAMTS20	7.27e-09	184	140	9	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma\|TCGA-Brain / Sample_Type by Project: Shred V9	SPTAN1 RICTOR CSMD3 ADAM22 DST MDN1 CASKIN2 DYNC1H1	9.40e-08	177	140	8	e8ab340b20cd41554c3841fe980e078e878af35f
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Stem_cells\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	NRIP1 CALB1 CNOT10 CPE ADARB1 TRPM3 TRPM1 CDH7	1.98e-07	195	140	8	2fa0216ba493d9722324c0a9a0c59c40e72b3c4e
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Stem_cells-retina_progenitors\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	NRIP1 CALB1 CNOT10 CPE ADARB1 TRPM3 TRPM1 CDH7	1.98e-07	195	140	8	06a437459717dc3c41ec343b1ec57cf910ecbdd8
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Macroglial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPC1 WSCD1 CADM4 RNF13 SLC1A2 APPL2 TMEM151A IL1RAP	2.22e-07	198	140	8	731a90f7e68b19e387499d63e3979af78b503b0c
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L3_RORB_CARTPT\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CALB1 ARHGEF28 STRIP2 NBPF19 SLIT2 CDH22 WDR86	1.67e-06	180	140	7	5e78b29fa1cbdcf502fee3577e5b45766b90d1dc
ToppCell	5'-Adult-LargeIntestine-Neuronal-Glial_mature\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CADM4 SLC35F1 CADM1 DST SYT14 SCN7A WDR86	2.01e-06	185	140	7	f607b6ee579562e2f92103fa5c7053df0170a229
ToppCell	5'-Adult-LargeIntestine-Neuronal\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CADM4 SLC35F1 CADM1 DST SYT14 SCN7A WDR86	2.01e-06	185	140	7	317f2c854f00aa5957319b818c85eeed7d72ec7f
ToppCell	5'-Adult-LargeIntestine-Neuronal-Glial_mature-Adult_Glia\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CADM4 SLC35F1 CADM1 DST SYT14 SCN7A WDR86	2.01e-06	185	140	7	7bb8fdfe04f85d25056380ec58222366de323a21
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	UAP1 ARHGEF28 SLC22A23 SH3BP4 SLIT2 DST CLNK	2.08e-06	186	140	7	a6ef5d5944af5689b5f27bef89cd05645eedbe50
ToppCell	droplet-Limb_Muscle-nan-24m-Macroglial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CADM4 SLC35F1 CSMD3 CADM1 TRPM3 ADAMTS20 IL1RAP	2.16e-06	187	140	7	a0bd2b0ec9e73521c245037b1dd51ff8cf24cbf5
ToppCell	droplet-Limb_Muscle-nan-24m-Macroglial-Schwann_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CADM4 SLC35F1 CSMD3 CADM1 TRPM3 ADAMTS20 IL1RAP	2.16e-06	187	140	7	f2af79a20438108c814a73f9e24cd986d537237f
ToppCell	droplet-Lung-nan-3m-Endothelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WSCD1 SOX11 TCN2 CADM1 CASKIN2 SCN7A GNA11	2.57e-06	192	140	7	42e4dafbe3e8b4a3c25d594f06b95430a1dd8b28
ToppCell	droplet-Lung-nan-3m-Endothelial-Capillary_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WSCD1 SOX11 UACA TCN2 CADM1 CASKIN2 SCN7A	2.66e-06	193	140	7	7cff1e859b296b1032eebcfc0f99a504f3bda2c9
ToppCell	proximal-3-Endothelial-Vein\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	WSCD1 GIMAP1 CPE ATP8B2 APPL2 PIK3C2B NEURL4	2.85e-06	195	140	7	c81eb541c15b866f9b6ca6a5f1751c5f1243f4fb
ToppCell	proximal-Endothelial-Vein-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	WSCD1 GIMAP1 CPE ATP8B2 APPL2 PIK3C2B NEURL4	2.85e-06	195	140	7	df00f94facc5d6107aac83cef3c64fefc7f8e562
ToppCell	proximal-Endothelial-Vein\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	WSCD1 GIMAP1 CPE ATP8B2 APPL2 PIK3C2B NEURL4	2.85e-06	195	140	7	0aebdd635a956dd2367883c1cf73d73ce9790635
ToppCell	facs-Brain_Non-Myeloid-Cortex\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPC1 WSCD1 CADM4 RNF13 CPE SLC1A2 TMEM151A	2.95e-06	196	140	7	256fe9bc0815f66a9afe11ba3507ef1372b52fd3
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPC1 WSCD1 CADM4 RNF13 CPE SLC1A2 APPL2	3.15e-06	198	140	7	a7e5de81eb7d3d23812c179a001adbaab1506596
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Macroglial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPC1 WSCD1 CADM4 RNF13 SLC1A2 APPL2 TMEM151A	3.15e-06	198	140	7	43a2ce64fa309bac89a44ea320e87ae2cc39f782
ToppCell	3'-GW_trimst-1-LargeIntestine-Neuronal-Glial_immature\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SOX11 CADM4 SLC35F1 CADM1 DST WDR86 IL1RAP	3.15e-06	198	140	7	c8272ac4d90f2367f538f66db40de911ad73ea7f
ToppCell	Macroglial-Astrocytes\|Macroglial / cells hierarchy compared to all cells using T-Statistic	ATP13A4 NBPF26 CPE SLC1A2 TENM2 NBPF19 TRPM3	3.37e-06	200	140	7	941536b7c32f1e63c70535233b2ccce0cd7bf96e
ToppCell	Macroglial-Astrocytes-SLC14A1---\|Macroglial / cells hierarchy compared to all cells using T-Statistic	ATP13A4 NBPF26 SLC1A2 TENM2 NBPF19 TRPM3 NBPF10	3.37e-06	200	140	7	d6fcbf4f4bc1b89a9929d7b114c6b907b6979900
ToppCell	Macroglial-Astrocytes-SLC14A1----L1-6\|Macroglial / cells hierarchy compared to all cells using T-Statistic	ATP13A4 NBPF26 SLC1A2 TENM2 NBPF19 TRPM3 NBPF10	3.37e-06	200	140	7	f861509b54185d89931db64da1b9d81986cc7938
ToppCell	Macroglial-Astrocytes-SLC14A1\|Macroglial / cells hierarchy compared to all cells using T-Statistic	ATP13A4 NBPF26 SLC1A2 TENM2 NBPF19 TRPM3 NBPF10	3.37e-06	200	140	7	16f468217427921fa18c6d078ffa990eb019b257
ToppCell	Macroglial-Astrocytes-SLC14A1--\|Macroglial / cells hierarchy compared to all cells using T-Statistic	ATP13A4 NBPF26 SLC1A2 TENM2 NBPF19 TRPM3 NBPF10	3.37e-06	200	140	7	0442894c39eec69850c090957a5dc7bcecd21e04
ToppCell	Macroglial-Astrocytes-SLC14A1-\|Macroglial / cells hierarchy compared to all cells using T-Statistic	ATP13A4 NBPF26 SLC1A2 TENM2 NBPF19 TRPM3 NBPF10	3.37e-06	200	140	7	01819446deeab9054f5cfe889d53bb49d137dbc0
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW23-Neuronal-GABAergic_neurons\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	SOX11 CALB1 TENM2 SLIT2 CADM1 DST FTH1	3.37e-06	200	140	7	c6bbd33bca86ac7a76a7ba704b3e141237d04549
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_11\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SH3BP4 CADM1 DST CASKIN2 CLNK MCOLN2	1.44e-05	166	140	6	b1bebcbe17386cb102b11d551e62d46156ce0c68
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_11\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SH3BP4 CADM1 DST CASKIN2 CLNK MCOLN2	1.49e-05	167	140	6	e44743b20a7435c579d8e999ddc4ca119d6753f2
ToppCell	COVID-19-Heart-Neuronal\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CADM4 SLC35F1 CADM1 DST SCN7A IL1RAP	1.54e-05	168	140	6	88c2c574f428c2502b5fe099bd73b0758f668ef6
ToppCell	droplet-Liver-HEPATOCYTES-1m-Epithelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT8 MAT1A GBE1 SLCO1B3 IL1RAP NNT	1.54e-05	168	140	6	b98af4043dfa5dfa4413e482879fad88de484675
ToppCell	droplet-Liver-HEPATOCYTES-1m-Epithelial-hepatocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT8 MAT1A GBE1 SLCO1B3 IL1RAP NNT	1.54e-05	168	140	6	073b53d4cee6bc8c5c6fce51cf6cd9c316478f69
ToppCell	droplet-Liver-HEPATOCYTES\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT8 MAT1A GBE1 SLCO1B3 IL1RAP NNT	1.59e-05	169	140	6	f195467438c589f87224bde7da720dea072d110c
ToppCell	droplet-Liver-HEPATOCYTES-1m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT8 MAT1A GBE1 SLCO1B3 IL1RAP NNT	1.59e-05	169	140	6	7785cab967a33560830c394c918d6ce625103858
ToppCell	COVID-19-Heart-Neuronal\|Heart / Disease (COVID-19 only), tissue and cell type	CADM4 SLC22A23 SLC35F1 CADM1 SCN7A IL1RAP	1.82e-05	173	140	6	6fb5f9e6536a5d57fd8e6657b494047a2d0bc9c7
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	UAP1 SLC22A23 ADAM22 SLIT2 BTN3A3 CLNK	1.94e-05	175	140	6	1d8da48236549c01381f777ce5b2937f9f86acc2
ToppCell	facs-Lung-nan-3m-Epithelial-club_cell_of_bronchiole\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT8 ARHGEF28 DNAI3 ADAM22 PHKB MORN5	2.07e-05	177	140	6	e5070934c674a46e070b0d52b9a374516bf6aea1
ToppCell	facs-Lung-nan-3m-Epithelial-Club_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT8 ARHGEF28 DNAI3 ADAM22 PHKB MORN5	2.07e-05	177	140	6	b37d821f4f3204daf7c568ac17a0af0ba97273d6
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PREPL ADAM22 PHF2 DST TRPM3 PCNX1	2.13e-05	178	140	6	fcbbcc44271515de1969b4732b6441c012693d5f
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NPC1 UAP1 SLC22A23 SH3BP4 SLIT2 CLNK	2.20e-05	179	140	6	e6ae070b4c52ba08167c7d64ea4cfbac0454c1bf
ToppCell	droplet-Kidney-KIDNEY-30m-Lymphocytic-Epcam____thick_ascending_tube_S_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF383 TENM2 STRIP2 PHKB CASKIN2 CDC25B	2.20e-05	179	140	6	4166c4e1a8748a79ac6a11fd0b97c5344be2321b
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c12-FOXP3\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SPTAN1 CPE OGDH ATP8B2 IKZF4 PCNX1	2.27e-05	180	140	6	6bb9f41c3a99d1bbe697f589fb2bcea9b7bfbeee
ToppCell	5'-Adult-SmallIntestine-Neuronal\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CADM4 SLC35F1 CADM1 SCN7A WDR86 IGSF1	2.27e-05	180	140	6	5e6e38ee0758ef2342a6a821c78ed24b57bb7b11
ToppCell	3'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CADM4 SLC35F1 CADM1 DST TRPM3 SCN7A	2.27e-05	180	140	6	b294f9db1e2ff51c94cde64fae4c2b057c0030a1
ToppCell	5'-Adult-SmallIntestine-Neuronal-Glial_mature-Adult_Glia\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CADM4 SLC35F1 CADM1 SCN7A WDR86 IGSF1	2.27e-05	180	140	6	b88cd7ae922782176c057342d1b9eb9b8e5e7204
ToppCell	5'-Adult-SmallIntestine-Neuronal-Glial_mature\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CADM4 SLC35F1 CADM1 SCN7A WDR86 IGSF1	2.27e-05	180	140	6	ebd6e719a03f25155fa8181be19469d04d6d10a6
ToppCell	3'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CADM4 SLC35F1 CADM1 TRPM3 SYT14 SCN7A	2.27e-05	180	140	6	38490017dd590e3fcfa7e88d8d15235d55f90cf1
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	UAP1 SLC22A23 CSMD3 SH3BP4 SLIT2 CLNK	2.34e-05	181	140	6	30729f0364f719c044712a51453e22dc2c1a232b
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	UACA DNAI3 ADARB1 TENM2 SLIT2 SCN7A	2.34e-05	181	140	6	9ede19228ba5c0668a9c06c915510b95585216ef
ToppCell	droplet-Limb_Muscle-nan-21m-Macroglial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CADM4 SLC35F1 CSMD3 SLIT2 CADM1 TRPM3	2.42e-05	182	140	6	a512863304fad80acaab60a8c6107eb7c9cbac99
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 CALB1 PREPL CADM1 SCN7A NNT	2.49e-05	183	140	6	2f0ee40e69ad1259e56e8ee4b352736900eb8901
ToppCell	droplet-Limb_Muscle-nan-3m-Macroglial-Schwann_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CADM4 SLC35F1 CSMD3 CADM1 TRPM3 ADAMTS20	2.49e-05	183	140	6	2cf36ad89584eb9f8b04de52a1b511b7f3527884
ToppCell	3'-GW_trimst-1-LargeIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CADM4 SLC35F1 CADM1 DST TRPM3 IL1RAP	2.49e-05	183	140	6	547b1fb9f9940cfc8d6e351d96acc0da44def57e
ToppCell	COVID-19-kidney-CD-IC-A\|kidney / Disease (COVID-19 only), tissue and cell type	UAP1 ADAM22 SH3BP4 SLIT2 GNA11 CLNK	2.49e-05	183	140	6	5c7597a5b2bf6a481ca2c7e68560179214150fa0
ToppCell	droplet-Limb_Muscle-nan-3m-Macroglial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CADM4 SLC35F1 CSMD3 CADM1 TRPM3 ADAMTS20	2.49e-05	183	140	6	98fee6838acfaee5e2e449ba088764ec06b8bc57
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_CACNG5\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM2 NBPF19 SLIT2 SCN7A NBPF10 NBPF14	2.57e-05	184	140	6	658f2e522055e88c92bc482a845c40f8f5f1a8e3
ToppCell	droplet-Limb_Muscle-nan-3m-Macroglial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CADM4 SLC35F1 CSMD3 CADM1 TRPM3 ADAMTS20	2.57e-05	184	140	6	da8d6e7944eb35e6cbea2feb7cbc2894787d723f
ToppCell	droplet-Limb_Muscle-nan-18m-Macroglial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CADM4 SLC35F1 CSMD3 CADM1 ADAMTS20 IL1RAP	2.57e-05	184	140	6	a7399a72f065d68800e3e0b2031d9894e0cc0ba4
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-mesothelial_cell-Mesothelium_(RGS5+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CPE TENM2 SH3BP4 PALS1 SCN7A TMEM151A	2.65e-05	185	140	6	11fbea1eb1d9a3e4480d0d2b0f7b02e2866b8142
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CADM4 SLC35F1 CADM1 DST TRPM3 SCN7A	2.73e-05	186	140	6	6f88b68735d0f7c9904eb8413e6007910d556185
ToppCell	Control-Fibroblasts-Other_FB\|Control / group, cell type (main and fine annotations)	UACA ADARB1 TENM2 SLIT2 DST SCN7A	2.81e-05	187	140	6	bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCell	droplet-Limb_Muscle-nan-18m-Macroglial-Schwann_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CADM4 SLC35F1 CSMD3 CADM1 ADAMTS20 IL1RAP	2.90e-05	188	140	6	8385fd384fc55e3b17802bb6698eb93b2c16d7f2
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	VPS13C RICTOR DDX3X PCNX1 TMEM131 DYNC1H1	2.90e-05	188	140	6	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SLC22A23 ADAM22 SLIT2 TRPM3 KLHL8 CLNK	2.90e-05	188	140	6	58ccb31cdf43167872ef0fc737e6f9c51ee2e060
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGEF28 SLC22A23 SH3BP4 SLIT2 DST CLNK	2.90e-05	188	140	6	e751cff2ac8fbc1487766c1871fcc5d1005286b0
ToppCell	facs-Lung\|facs / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	WSCD1 SOX11 TCN2 GIMAP1 CASKIN2 SCN7A	2.90e-05	188	140	6	f7292fc8e914f222828dcdb0a017d716207a97f6
ToppCell	droplet-Heart-HEART-1m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CADM4 SLC22A23 SLC35F1 CADM1 SCN7A ADAMTS20	2.90e-05	188	140	6	921a2c9212a0f2a00fd72c594d80924f27e8b9b7
ToppCell	3'-GW_trimst-2-LargeIntestine-Neuronal\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CADM4 SLC35F1 CADM1 DST TRPM3 SYT14	2.90e-05	188	140	6	ccd2541892112a7a303f766adf9a7afeb754498c
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 TENM2 SLIT2 DST PDILT NNT	2.90e-05	188	140	6	14e120b20e76baa07b6510a94f0c2dcdfdd52357
ToppCell	facs-Lung\|facs / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WSCD1 SOX11 TCN2 GIMAP1 CASKIN2 SCN7A	2.90e-05	188	140	6	e2b6e14579ec649a2bc106d9c99bb78ceb16ede3
ToppCell	droplet-Limb_Muscle-nan-18m-Macroglial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CADM4 SLC35F1 CSMD3 CADM1 ADAMTS20 IL1RAP	2.90e-05	188	140	6	cb9d0b48e2fd9cc576132803273b9c0382900944
ToppCell	droplet-Heart-HEART-1m-Neuronal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CADM4 SLC22A23 SLC35F1 CADM1 SCN7A ADAMTS20	2.99e-05	189	140	6	a618a1ddf5097a010c6c2c7341f3a0bd46a29c02
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 TENM2 SLIT2 DST PDILT NNT	2.99e-05	189	140	6	443359d90fafae0c1de6bdcce9e8c95df6ea4de8
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SLC22A23 CSMD3 ADARB1 SLIT2 DST SCN7A	2.99e-05	189	140	6	203c80030df08ae112f9ae4043709f455d87ce89
ToppCell	droplet-Heart-HEART-1m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CADM4 SLC22A23 SLC35F1 CADM1 SCN7A ADAMTS20	2.99e-05	189	140	6	4e61f9cd1c06bddb47ebf98affc0f97770e26e8c
ToppCell	PND01-03-samps-Endothelial\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	SOX11 TCN2 GIMAP1 PIK3C2B CASKIN2 SCN7A	3.08e-05	190	140	6	1357bd4527399d7013ee33272bda7453f472999a
ToppCell	PND01-03-samps-Endothelial-Postnatal_endothelial\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	SOX11 TCN2 GIMAP1 PIK3C2B CASKIN2 SCN7A	3.08e-05	190	140	6	5130fb325f80f591b9b36beacb8072c4472304f2
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 TENM2 SLIT2 DST PDILT TMEM151A	3.17e-05	191	140	6	5a5b5402a077b3189ca156f2bac5f47ad780aebf
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 TENM2 SLIT2 DST PDILT TMEM151A	3.17e-05	191	140	6	78bcce497920cc5b3bef083eab50deb1cc82cd2e
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-mesothelial_cell\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KRT8 CPE TENM2 SH3BP4 SCN7A TMEM151A	3.26e-05	192	140	6	2f539653a20006bef814e6b4acd1023d6fdad5c6
ToppCell	COPD-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	UACA ADARB1 SLIT2 DST SCN7A MCOLN2	3.26e-05	192	140	6	62904f94dfce430456f05066522cbf9bd29f4d7e
ToppCell	5'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Differentiating_glia\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CADM4 SLC35F1 CADM1 DST TRPM3 WDR86	3.36e-05	193	140	6	d5930f7bd9b299f792212d40a3272a37adf64a82
ToppCell	T_cells-Central_memory_CD4+_T_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	GIMAP1 ATP8B2 PCNX1 WDR86 CDC25B CD96	3.36e-05	193	140	6	725326d7e3604736b607c19f4069c81cb4f2d20c
ToppCell	Control-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	UACA ADARB1 CADM1 DST SCN7A MCOLN2	3.36e-05	193	140	6	5896242f713ae5fd1a4ebb63827f15d7279dced2
ToppCell	droplet-Lung-nan-3m-Endothelial-endothelial_cell_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WSCD1 SOX11 TCN2 CADM1 CASKIN2 SCN7A	3.36e-05	193	140	6	ab54c4b8ae17580e2f2bfcdcb1456fe52dedafe9
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CSMD3 ADARB1 TENM2 SLIT2 DST SCN7A	3.46e-05	194	140	6	011e14d9ed1393275f892060e7708ffadcd0767f
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	SOX11 TENM2 ADAM22 SLIT2 DST RERE	3.46e-05	194	140	6	b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCell	3'-Pediatric_IBD-SmallIntestine-Neuronal-Glial_mature-Adult_Glia\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CADM4 SLC35F1 CADM1 DST SCN7A WDR86	3.46e-05	194	140	6	d429bb5e422a07bd92f0dc48cd51528e8b7d9a72
ToppCell	COVID-19-Myeloid-TRAM2\|Myeloid / Condition, Lineage and Cell class	ARHGEF28 CPE DST SVIL FTH1 HERC5	3.46e-05	194	140	6	4060a60c0271e7397b07993a1ef47b3291bba6e3
ToppCell	3'-Pediatric_IBD-SmallIntestine-Neuronal\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CADM4 SLC35F1 CADM1 DST SCN7A WDR86	3.46e-05	194	140	6	bffdf6db0bf3fb338e7bb0789ae7dcde1fce0094
ToppCell	3'-Pediatric_IBD-SmallIntestine-Neuronal-Glial_mature\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CADM4 SLC35F1 CADM1 DST SCN7A WDR86	3.46e-05	194	140	6	408dfc7060095972a54ae37ae8105521df6fbbee
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	SOX11 TENM2 ADAM22 SLIT2 DST RERE	3.56e-05	195	140	6	0e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell\|Adult / Lineage, Cell type, age group and donor	UACA ADARB1 SLIT2 DST SCN7A MCOLN2	3.56e-05	195	140	6	61c9e09fc84d1012e472185d70ad0a06cee30d6e
ToppCell	PBMC-Severe-Myeloid-cDC-cDC-cDC_9\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	MAT2A SH3BP4 DST MTMR14 CARD9 HERC5	3.56e-05	195	140	6	dd28c63b53f2a97e3fac127294a465870dc371b3
ToppCell	PBMC-Severe-Myeloid-cDC-cDC-cDC_9\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MAT2A SH3BP4 DST MTMR14 CARD9 HERC5	3.56e-05	195	140	6	d6ff38535898f90be6719cd5152291f2f4f8a746
ToppCell	5'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CADM4 SLC35F1 CADM1 DST TRPM3 SCN7A	3.66e-05	196	140	6	e6adcfe1a00d4910e0b92848f8a80224e0d6db12
ToppCell	droplet-Bladder-nan-3m-Epithelial-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERN2 IKZF4 SH3BP4 SLIT2 LIG3	3.73e-05	119	140	5	018162114bc22a9780fded5887f1f78211851700
Disease	bilirubin metabolic disorder (implicated_via_orthology)	SLCO1B3 SLCO1B1 SLCO1B7	8.69e-07	5	132	3	DOID:2741 (implicated_via_orthology)
Disease	hexadecenedioate (C16:1-DC) measurement	SLCO1B3 SLCO1B1 SLCO1B7	7.21e-06	9	132	3	EFO_0800562
Disease	HYPERBILIRUBINEMIA, ROTOR TYPE, DIGENIC	SLCO1B3 SLCO1B1	1.99e-05	2	132	2	C4016905
Disease	Rotor Syndrome	SLCO1B3 SLCO1B1	1.99e-05	2	132	2	C0220991
Disease	Rotor syndrome	SLCO1B3 SLCO1B1	1.99e-05	2	132	2	cv:C0220991
Disease	Phakomatosis cesioflammea	GNA11 GNAQ	1.99e-05	2	132	2	C3838883
Disease	Congenital hemangioma	GNA11 GNAQ	1.99e-05	2	132	2	C0235753
Disease	Port-wine stain with oculocutaneous melanosis	GNA11 GNAQ	1.99e-05	2	132	2	C1274879
Disease	HYPERBILIRUBINEMIA, ROTOR TYPE	SLCO1B3 SLCO1B1	1.99e-05	2	132	2	237450
Disease	glycochenodeoxycholate glucuronide (1) measurement	SLCO1B3 SLCO1B1 SLCO1B7	2.42e-05	13	132	3	EFO_0800474
Disease	X-23756 measurement	SLCO1B1 SLCO1B7	1.97e-04	5	132	2	EFO_0022126
Disease	Malignant melanoma of iris	GNA11 GNAQ	1.97e-04	5	132	2	C0346373
Disease	Malignant melanoma of choroid	GNA11 GNAQ	1.97e-04	5	132	2	C0346388
Disease	age at first birth measurement	SOX11 ADARB1 IKZF4 SYT14 IGSF1	2.10e-04	120	132	5	EFO_0009101
Disease	bilirubin metabolic disorder (is_implicated_in)	SLCO1B3 SLCO1B1	2.94e-04	6	132	2	DOID:2741 (is_implicated_in)
Disease	Failure to Thrive	TCN2 RNF13	2.94e-04	6	132	2	C0015544
Disease	amyotrophic lateral sclerosis (implicated_via_orthology)	ATP13A4 ALS2 ADARB1	3.25e-04	30	132	3	DOID:332 (implicated_via_orthology)
Disease	Colorectal Carcinoma	TCF3 TCN2 ABCA13 SLCO1B3 CPE CSMD3 LIG3 FAT1 CDH22 PDILT CDH7	3.28e-04	702	132	11	C0009402
Disease	MASA syndrome (implicated_via_orthology)	TRPM3 TRPM1	4.11e-04	7	132	2	DOID:0060246 (implicated_via_orthology)
Disease	obesity (implicated_via_orthology)	TCF3 CPE ADARB1 ADAMTS20 GNA11 GNAQ	4.26e-04	215	132	6	DOID:9970 (implicated_via_orthology)
Disease	deoxycholic acid glucuronide measurement	SLCO1B3 SLCO1B1	5.46e-04	8	132	2	EFO_0800575
Disease	breast ductal carcinoma (is_marker_for)	SLCO1B3 RICTOR	5.46e-04	8	132	2	DOID:3007 (is_marker_for)
Disease	Uveal melanoma	GNA11 GNAQ	5.46e-04	8	132	2	C0220633
Disease	ceramide measurement	SLCO1B3 ERN2 SLCO1B1 PREPL SLCO1B7 MDN1	6.80e-04	235	132	6	EFO_0010222
Disease	X-21467 measurement	SLCO1B3 SLCO1B1	7.00e-04	9	132	2	EFO_0020007
Disease	vitamin D measurement	NRIP1 MAT1A SLCO1B1 PDILT GNAQ TMEM151A KLHL8	8.16e-04	336	132	7	EFO_0004631
Disease	lysophosphatidylethanolamine measurement	SLCO1B1 SLCO1B7 FTH1	8.24e-04	41	132	3	EFO_0010225
Disease	social interaction measurement	GBE1 TENM2 PHF2 CDH7	8.55e-04	94	132	4	EFO_0009592
Disease	phosphatidylinositol measurement	PRPF31 SLCO1B3 SLCO1B1 FTH1	8.89e-04	95	132	4	EFO_0010230
Disease	Intellectual Disability	TCN2 RNF13 SLC1A2 PREPL ZBTB24 DDX3X TRPM3 DYNC1H1	9.35e-04	447	132	8	C3714756
Disease	Ankylosing spondylitis	TBKBP1 CARD9	1.06e-03	11	132	2	C0038013
Disease	Vitiligo	SLC1A2 IKZF4 RERE CLNK	1.12e-03	101	132	4	EFO_0004208
Disease	Agammaglobulinemia	TCF3 TCN2	1.27e-03	12	132	2	C0001768
Disease	cholestasis (biomarker_via_orthology)	SLCO1B3 SLCO1B1 SLCO1B7	1.39e-03	49	132	3	DOID:13580 (biomarker_via_orthology)
Disease	age at menarche	WSCD1 TENM2 CADM1 DST TRPM3 PDILT GNAQ RERE IGSF1	1.45e-03	594	132	9	EFO_0004703
Disease	phosphocreatine measurement	TENM2 ADAMTS20	1.50e-03	13	132	2	EFO_0010521
Disease	Colorectal Neoplasms	TCN2 ABCA13 SLCO1B3 FAT1 CDH22 CDH7	1.58e-03	277	132	6	C0009404
Disease	lipid metabolism disorder (implicated_via_orthology)	MAT1A MAT2A	2.01e-03	15	132	2	DOID:3146 (implicated_via_orthology)
Disease	Glycogen storage disease	GBE1 PHKB	2.58e-03	17	132	2	cv:C0017919
Disease	Vitiligo	IKZF4 CLNK	2.58e-03	17	132	2	C0042900
Disease	X-21441 measurement	SLCO1B3 SLCO1B7	2.58e-03	17	132	2	EFO_0800814
Disease	Stevens-Johnson syndrome, toxic epidermal necrolysis	SLC22A23 ADAM22	2.58e-03	17	132	2	EFO_0004276, EFO_0004775
Disease	acylcarnitine measurement	SLC22A23 SLCO1B1 SLCO1B7 METTL24	2.59e-03	127	132	4	EFO_0005059
Disease	forced expiratory volume	ILF3 SLCO1B1 ZBTB24 IKZF4 DST PIK3C2B CARD9 LOXL1 NNT HERC5	2.95e-03	789	132	10	EFO_0004314
Disease	neck circumference	USP44 ADAMTS20	3.23e-03	19	132	2	EFO_0011043
Disease	diacylglycerol 38:3 measurement	PRPF31 FTH1	3.23e-03	19	132	2	EFO_0020065
Disease	HbA1c measurement, response to sulfonylurea	SLCO1B1 SLCO1B7	3.94e-03	21	132	2	EFO_0004541, EFO_0007922
Disease	severe acute respiratory syndrome, COVID-19	ARHGEF28 ZFYVE1 TENM2 PDILT SYT14 TRPM1 GNAQ	4.07e-03	447	132	7	EFO_0000694, MONDO_0100096

Protein segments in the cluster

Peptide	Gene	Start	Entry
LGSDLHIEVKGYEDG	BTN3A3	146	O00478
IYDGKDKTTHLLGAF	CSMD3	1296	Q7Z407
SAAGFHLEYTAIGLD	CSMD3	2036	Q7Z407
KHGVLLTEDGEVYSF	ALS2	51	Q96Q42
EVSDKGREGSYHFAL	ATP13A4	781	Q4VNC1
SGGHVKLEEDVDLGY	ADAM22	636	Q9P0K1
TEGLKDVYSFTLLHG	ABCA13	1766	Q86UQ4
EDGPSAALHSKLYEA	ANKRD61	21	A6NGH8
EGTFGDKTDTHLKEY	DNAI3	311	Q8IWG1
TGHKGYVAFLESLEL	CARD9	71	Q9H257
DASFLAAGYTEVHLG	ADAMTS20	96	P59510
HSYGDVFDVLGHKAE	ATP8B2	431	P98198
HSLFLTDKGEVYSCG	RCC1L	241	Q96I51
DYETGDFERTLKGHT	PAFAH1B1	136	P43034
IIHGSGYSDEDKRGF	GNAQ	61	P50148
YEELQSLAGKHGDDL	KRT8	286	P05787
KLHIYAELGELSGFE	ARHGEF28	1236	Q8N1W1
KKGADSLEDFLYHEG	DDX3X	451	O00571
EISYSIEDGNEHGKF	FAT1	1286	Q14517
KYLETPEFSGDGAHA	VCPKMT	51	Q9H867
KSYGEDGTAAKHLFF	MDN1	4586	Q9NU22
TVAKKLHDGGLDYFE	LYZL4	26	Q96KX0
SGDTHLFDKVRGYDI	MTMR14	186	Q8NCE2
AHFGTDETILDGKEY	IL1RAP	391	Q9NPH3
LADGYSEKIEHVGDF	DST	3286	Q03001
GLELGAAEKEEDYHT	FYCO1	321	Q9BQS8
AVKHIGYDDSSKGFD	MAT2A	86	P31153
GKDETGFYVSKALVH	ERN2	291	Q76MJ5
DEFSHYDLLDAATGK	LOXL1	456	Q08397
FGYVTEDGDTALHLA	NFKBIB	51	Q15653
SYSDSHEQLKDILGG	PCNX1	2001	Q96RV3
KDFHGSLLRFYENGE	KLHL8	51	Q9P2G9
EGHVRTFDGKSYSFD	MUC19	1281	Q7Z5P9
KGSSVGELYLDDGHS	GANC	806	Q8TET4
TIKHIGYDDSAKGFD	MAT1A	86	Q00266
DLEFKYPAGHGSASE	NRIP1	906	P48552
DSDHRELIGDYSKAF	CDC25B	386	P30305
ELEHSDSGYEPSFGK	LCA5L	566	O95447
GDGFHGDVYLTVKLL	LIG3	296	P49916
GLKYDFLSESGESHA	ADARB1	246	P78563
GHSEEKLGFHYEDII	RICTOR	71	Q6R327
TGTALHEAALYGKTE	CASKIN2	221	Q8WXE0
YHRSFGLDDDSLAKL	IRGC	301	Q6NXR0
DFYLSCSLSHGGKEL	PIK3C2B	651	O00750
GDYHSLALSKGGELF	HERC5	146	Q9UII4
FVLEEGHDYTSSKGQ	NPC1	891	O15118
GHYFDTAIVNSDLDK	PALS1	636	Q8N3R9
GLHDAYLETRDFKGS	SMPD2	196	O60906
KLEAADEGSGDVKYH	OGDH	336	Q02218
YFTHEAKGADDAADA	CADM1	406	Q9BY67
LAEYLFDKHTLGDSD	FTH1	166	P02794
DIGGALSKLSELHAY	HBZ	76	P02008
FKIVLDSDAAEYGGH	GBE1	646	Q04446
FTRKEDLAGGSLHDY	GIMAP1	151	Q8WWP7
DFLLHTVGAEDSGNY	IGSF1	926	Q8N6C5
DSFGAGIVYHLSKSE	SLC1A2	486	P43004
IIHGAGYSEEDKRGF	GNA11	61	P29992
YELISETGGSHDKRF	ILF3	541	Q12906
LHFDADGSGYLEGKE	CALB1	21	P05937
EGIDHDVTSAKDGDY	CPE	396	P16870
QKGSYLTHEASGLDE	CADM4	351	Q8NFZ8
GKGDEEVISTLHYFS	APPL2	76	Q8NEU8
EGYTHDAGFDNDIAL	MASP2	521	O00187
GADGSRADKAGHYLE	MAN1A2	471	O60476
YLEGIFTGSADIKHL	DYNC1H1	1546	Q14204
GYGSDGLKLLSHEES	HBP1	256	O60381
LYVGKIHSDSDEGDG	CDH22	81	Q9UJ99
IHSDSDEGDGAIKYT	CDH22	86	Q9UJ99
LHSDVDKGDGSIKYI	CDH7	71	Q9ULB5
DNHRSLASYGLKDGD	DDI2	56	Q5TDH0
GGYEKDVELVAHHSL	IKZF4	351	Q9H2S9
FKHLFLKGYSGTDED	MCOLN2	101	Q8IZK6
AAGYAHGLVFSTKEL	NEURL4	936	Q96JN8
DAGSYTLHIIKGDDG	PSG1	116	P11464
HTGDELLSYEEYGHL	PHKB	156	Q93100
RLYSLGLGSDDTHFE	METTL24	181	Q5JXM2
GEASKFSDDHYRVAG	NNT	96	Q13423
YKGEHTLKGFSDFLE	PDILT	476	Q8N807
DKDLDSFSEGSLGSH	SOX11	396	P35716
GSSSESEDEALGKYH	SYT14	86	Q8NB59
SDEFSEIDQGKGYHI	TEX55	466	Q96M34
DSKFLNHEGYGIGDD	RSPRY1	381	Q96DX4
VKDSYTDFHIDSGGA	PHF2	241	O75151
FSKGDHLYVLDTSGG	SH3BP4	76	Q9P0V3
LEFEYGDADGHAAEL	STRIP2	51	Q9ULQ0
GDADGHAAELSELYS	STRIP2	56	Q9ULQ0
ESKDYALHVGDGSSD	SVIL	181	O95425
ALVADYGHDGTKTDT	NDUFAF7	296	Q7L592
YALEEKHVGFSLDVG	NBPF8	776	Q3BBV2
YALEEKHVGFSLDVG	NBPF9	811	P0DPF3
YALEEKHVGFSLDVG	NBPF10	811	Q6P3W6
YALEEKHVGFSLDVG	NBPF10	2031	Q6P3W6
YALEEKHVGFSLDVG	NBPF10	3251	Q6P3W6
YALEEKHVGFSLDVG	NBPF12	1326	Q5TAG4
YALEEKHVGFSLDVG	NBPF14	471	Q5TI25
YALEEKHVGFSLDVG	NBPF19	1516	A0A087WUL8
YALEEKHVGFSLDVG	NBPF19	2736	A0A087WUL8
YALEEKHVGFSLDVG	NBPF20	196	P0DPF2
YALEEKHVGFSLDVG	NBPF20	1416	P0DPF2
YALEEKHVGFSLDVG	NBPF20	2636	P0DPF2
YALEEKHVGFSLDVG	NBPF20	3856	P0DPF2
YALEEKHVGFSLDVG	NBPF20	5076	P0DPF2
YALEEKHVGFSLDVG	NBPF26	771	B4DH59
AELKDYSGLHDAAAA	SLC22A23	656	A1A5C7
VLDSAFLEGGHEKVY	PRORSD1P	121	A6NEY8
NSLKDEFTYEKGGHL	RNF13	156	O43567
KDTHYFVKIGSADGD	TENM2	2616	Q9NT68
LNTLHESGYDAGKAL	RERE	366	Q9P2R6
GEFDYSAHGVRDVSK	TMEM151A	191	Q8N4L1
DFAKEGHSSLYLGTV	SLCO1B7	151	G3V0H7
LGLSYIDDFAKEGHS	SLCO1B1	191	Q9Y6L6
IDDFAKEGHSSLYLG	SLCO1B1	196	Q9Y6L6
EDVLKKAHELGGFTY	TCN2	356	P20062
YHGETLLASDKCGEA	BROX	256	Q5VW32
AFHDKGSLTDYLKGN	ACVR2B	266	Q13705
AVLDGAKGHSDDDYD	CLNK	56	Q7Z7G1
SGSLKFLGHLYAAEA	CNOT10	566	Q9H9A5
ETYTLTLEHKGAGEG	C11orf96	91	Q7Z7L8
GIGLTSKYLSEDFHA	SLC35F1	76	Q5T1Q4
YSEFLTGEGHLKVSG	ZYG11B	306	Q9C0D3
YLEQFGDSHGSGAKL	ZC3H6	946	P61129
GLTKHGLEYSSFGDV	ZNF383	106	Q8NA42
SHFILSDDGTVGKYG	TRPM6	246	Q9BX84
DGSFLHDEKEGIYIT	CD96	306	P40200
SYDGGLHGLQSKIED	TCF3	381	P15923
GRASDILAFGHKYSE	TRPM3	391	Q9HCF6
ILAFGHKYSEEGGLI	TRPM3	396	Q9HCF6
EVEGHLASDDYGKDL	SPTAN1	696	Q13813
FKDHVSLGDYEIHDG	UBL5	51	Q9BZL1
LGISYIDDFAKEGHS	SLCO1B3	191	Q9NPD5
IDDFAKEGHSSLYLG	SLCO1B3	196	Q9NPD5
AEVLDGYLGFDHAAT	TMEM131	426	Q92545
DSFHESTEGKVGYEL	PRPF31	306	Q8WWY3
AEKGTHSGEFIYGLE	VPS13C	126	Q709C8
KEAIAEHAKDTGEGY	PREPL	661	Q4J6C6
DEDSGILLYKGDKDH	SLIT2	1191	O94813
DYGKDLVASEGLFHS	SPTA1	291	P02549
GEGLESYVADKEFHA	UAP1	491	Q16222
GDASEAYLKHFTKEL	ZFYVE1	281	Q9HBF4
GSGRASDILSFAHKY	TRPM1	281	Q7Z4N2
SDILSFAHKYCEEGG	TRPM1	286	Q7Z4N2
NRFKYFESDHLGSGS	UACA	371	Q9BZF9
DYKLVGDQEDHGSAK	ZBTB24	266	O43167
DFEYSKRDLVGHGAF	ULK2	6	Q8IYT8
LALYHGGDDALLSDF	ZNHIT2	226	Q9UHR6
ESYSGHLKGTFAAIG	SLC35G1	216	Q2M3R5
GDRDVHATKEGAYFD	SCN7A	1656	Q01118
DDGHERTLKGAVFYD	WSCD1	151	Q658N2
RGFAHGSVYKSEFID	POLR1B	766	Q9H9Y6
KEGAKHFSGLEEAVY	CCT8	16	P50990
HGFSLYEIKDGSLLE	TBKBP1	86	A7MCY6
LKYHAGTLFTGSGDA	WDR86	281	Q86TI4
GDDSYFLHDGAQSLL	USP44	126	Q9H0E7
KGFHLDVEDYLSGVL	TSN	131	Q15631
GLAIKGTYTFSDGLH	MORN5	61	Q5VZ52