Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncytoskeletal motor activity

DNAH10 MYO5B DNAI1 KIF3B DNAH17 DNAH11

3.36e-051181036GO:0003774
GeneOntologyMolecularFunctionnatural killer cell lectin-like receptor binding

MICB ULBP2 RAET1L

8.60e-05171033GO:0046703
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH10 DNAH17 DNAH11

1.03e-04181033GO:0008569
GeneOntologyMolecularFunctioncytoskeletal protein binding

KLHL1 MYO5B SYNE1 IPP ARFGEF2 KATNAL1 NEB CCDC66 KIF3B LMO7 RMDN1 SVIL SYNE2 MYBPC1 MYBPC3 NLRP5

1.55e-04109910316GO:0008092
GeneOntologyMolecularFunctioncytoskeleton-nuclear membrane anchor activity

SYNE1 SYNE2

2.61e-0451032GO:0140444
GeneOntologyMolecularFunctionphosphatidylcholine transfer activity

PITPNA PITPNB

3.90e-0461032GO:0120019
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH10 DNAH17 DNAH11

3.98e-04281033GO:0051959
GeneOntologyMolecularFunctionmicrotubule motor activity

DNAH10 KIF3B DNAH17 DNAH11

4.71e-04701034GO:0003777
GeneOntologyMolecularFunctionactin binding

KLHL1 MYO5B SYNE1 IPP NEB SVIL SYNE2 MYBPC1 MYBPC3

8.34e-044791039GO:0003779
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAH10 DNAH17 DNAH11

9.12e-04371033GO:0045505
GeneOntologyMolecularFunctionATP-dependent activity

DNAH10 MYO5B ABCC9 SMARCAD1 KATNAL1 KIF3B DQX1 DNAH17 ATP6V1C2 DNAH11

1.27e-0361410310GO:0140657
GeneOntologyMolecularFunctionphosphatidylinositol transfer activity

PITPNA PITPNB

1.41e-03111032GO:0008526
GeneOntologyMolecularFunctionstructural constituent of muscle

NEB MYBPC1 MYBPC3

1.42e-03431033GO:0008307
GeneOntologyMolecularFunctionquaternary ammonium group binding

CHRNA2 PITPNA PITPNB

1.72e-03461033GO:0050997
GeneOntologyBiologicalProcessorganelle assembly

TBC1D9B SYNE1 PTPN23 NEB FSIP2 DNAI1 NCOR1 CCDC66 KIF3B WASHC5 CEP72 MTOR DNAH17 SYNE2 RAB39A ATM MYBPC1 MYBPC3

6.05e-0611389818GO:0070925
GeneOntologyBiologicalProcessmicrotubule cytoskeleton organization

CDK11A KATNAL1 CUL7 FSIP2 DNAI1 NCOR1 CCDC66 KIF3B WASHC5 CEP72 RMDN1 DNAH17 SYNE2 NLRP5

7.62e-067209814GO:0000226
GeneOntologyBiologicalProcessmicrotubule-based process

DNAH10 CDK11A KATNAL1 CUL7 FSIP2 DNAI1 NCOR1 CCDC66 KIF3B WASHC5 CEP72 RMDN1 DNAH17 SYNE2 DNAH11 NLRP5

3.68e-0510589816GO:0007017
GeneOntologyBiologicalProcessantigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent

MICB ULBP2 RAET1L

5.57e-0516983GO:0002486
GeneOntologyBiologicalProcessantigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway

MICB ULBP2 RAET1L

6.74e-0517983GO:0002484
GeneOntologyBiologicalProcessantigen processing and presentation of endogenous peptide antigen via MHC class Ib

MICB ULBP2 RAET1L

6.74e-0517983GO:0002476
GeneOntologyBiologicalProcesschromosome segregation

SMARCAD1 NCAPH2 NCOR1 KIF3B WASHC5 RMDN1 SMARCC1 SPATA22 ATM CDC23

7.34e-054659810GO:0007059
GeneOntologyBiologicalProcessantigen processing and presentation of peptide antigen via MHC class Ib

MICB ULBP2 RAET1L

8.06e-0518983GO:0002428
GeneOntologyBiologicalProcesscilium organization

TBC1D9B SYNE1 PTPN23 FSIP2 DNAI1 CCDC66 KIF3B DNAH17 SYNE2 TTC17

8.90e-054769810GO:0044782
GeneOntologyBiologicalProcessantigen processing and presentation of endogenous peptide antigen via MHC class I

MICB ULBP2 RAET1L

1.72e-0423983GO:0019885
GeneOntologyBiologicalProcessdendrite development

KLHL1 MYO5B SYNE1 DOCK10 MCF2 CUL7 MTOR PTPRZ1

1.97e-04335988GO:0016358
GeneOntologyBiologicalProcessmuscle cell differentiation

DOCK1 SYNE1 LAMA2 NEB CHUK MTOR SVIL CDON MYBPC1 MYBPC3

2.17e-045319810GO:0042692
GeneOntologyBiologicalProcessantigen processing and presentation of endogenous peptide antigen

MICB ULBP2 RAET1L

2.22e-0425983GO:0002483
GeneOntologyBiologicalProcessantigen processing and presentation via MHC class Ib

MICB ULBP2 RAET1L

2.22e-0425983GO:0002475
GeneOntologyBiologicalProcesscilium assembly

TBC1D9B SYNE1 PTPN23 FSIP2 DNAI1 CCDC66 KIF3B DNAH17 SYNE2

2.65e-04444989GO:0060271
GeneOntologyBiologicalProcessnuclear chromosome segregation

NCAPH2 KIF3B WASHC5 RMDN1 SMARCC1 SPATA22 ATM CDC23

2.97e-04356988GO:0098813
GeneOntologyCellularComponentdendritic spine

ARHGAP32 CALB1 MYO5B SYNE1 DOCK10 LAMA2 ARFGEF2 KIF3B PTPRZ1

2.89e-062421029GO:0043197
GeneOntologyCellularComponentneuron spine

ARHGAP32 CALB1 MYO5B SYNE1 DOCK10 LAMA2 ARFGEF2 KIF3B PTPRZ1

3.42e-062471029GO:0044309
GeneOntologyCellularComponentcytoplasmic region

DNAH10 MYO5B ARFGEF2 CHRNA2 FABP2 DNAI1 KIF3B DNAH17 DNAH11 NLRP5

1.06e-0536010210GO:0099568
GeneOntologyCellularComponentapical cortex

MYO5B FABP2 NLRP5

1.32e-05101023GO:0045179
GeneOntologyCellularComponentmicrotubule associated complex

DNAH10 KATNAL1 DNAI1 KIF3B DNAH17 DNAH11

1.39e-041611026GO:0005875
GeneOntologyCellularComponentdynein complex

DNAH10 DNAI1 DNAH17 DNAH11

1.40e-04541024GO:0030286
GeneOntologyCellularComponentsupramolecular fiber

DNAH10 SYNE1 ARFGEF2 ABCC9 KATNAL1 NEB DNAI1 CCDC66 KIF3B RMDN1 SVIL DNAH17 SYNE2 MYBPC1 DNAH11 MYBPC3

1.83e-04117910216GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

DNAH10 SYNE1 ARFGEF2 ABCC9 KATNAL1 NEB DNAI1 CCDC66 KIF3B RMDN1 SVIL DNAH17 SYNE2 MYBPC1 DNAH11 MYBPC3

1.98e-04118710216GO:0099081
GeneOntologyCellularComponentaxonemal dynein complex

DNAH10 DNAI1 DNAH17

2.40e-04251023GO:0005858
GeneOntologyCellularComponentmicrotubule

DNAH10 ARFGEF2 KATNAL1 DNAI1 CCDC66 KIF3B RMDN1 SVIL DNAH17 DNAH11

2.79e-0453310210GO:0005874
GeneOntologyCellularComponentmyofibril

SYNE1 ABCC9 NEB SVIL SYNE2 MYBPC1 MYBPC3

3.85e-042731027GO:0030016
GeneOntologyCellularComponentpostsynapse

DOCK1 ARHGAP32 CALB1 MYO5B SYNE1 DOCK10 LAMA2 ARFGEF2 NCAM1 CHRNA2 KIF3B MTOR PTPRZ1 GRIN3B

4.21e-04101810214GO:0098794
GeneOntologyCellularComponentcontractile muscle fiber

SYNE1 ABCC9 NEB SVIL SYNE2 MYBPC1 MYBPC3

5.52e-042901027GO:0043292
GeneOntologyCellularComponentsomatodendritic compartment

ARHGAP32 CALB1 KLHL1 MYO5B SYNE1 DOCK10 LAMA2 ARFGEF2 NCAM1 KIF3B WASHC5 MTOR PTPRZ1 WDFY3 GRIN3B

8.88e-04122810215GO:0036477
GeneOntologyCellularComponentplasma membrane bounded cell projection cytoplasm

DNAH10 ARFGEF2 CHRNA2 DNAI1 KIF3B DNAH17 DNAH11

9.32e-043171027GO:0032838
GeneOntologyCellularComponentmicrotubule organizing center attachment site

SYNE1 SYNE2

1.26e-03111022GO:0034992
GeneOntologyCellularComponentmeiotic nuclear membrane microtubule tethering complex

SYNE1 SYNE2

1.26e-03111022GO:0034993
GeneOntologyCellularComponentnuclear membrane protein complex

SYNE1 SYNE2

1.26e-03111022GO:0106083
GeneOntologyCellularComponentnuclear membrane microtubule tethering complex

SYNE1 SYNE2

1.26e-03111022GO:0106094
GeneOntologyCellularComponentcell cortex region

MYO5B FABP2 NLRP5

1.38e-03451023GO:0099738
GeneOntologyCellularComponentsarcomere

SYNE1 ABCC9 NEB SYNE2 MYBPC1 MYBPC3

1.40e-032491026GO:0030017
GeneOntologyCellularComponentouter dynein arm

DNAI1 DNAH17

1.51e-03121022GO:0036157
GeneOntologyCellularComponentdendrite

ARHGAP32 CALB1 KLHL1 MYO5B SYNE1 DOCK10 LAMA2 ARFGEF2 KIF3B MTOR PTPRZ1

3.10e-0385810211GO:0030425
GeneOntologyCellularComponentdendritic tree

ARHGAP32 CALB1 KLHL1 MYO5B SYNE1 DOCK10 LAMA2 ARFGEF2 KIF3B MTOR PTPRZ1

3.16e-0386010211GO:0097447
DomainMHC_I/II-like_Ag-recog

HLA-DPA1 MICB ULBP2 RAET1L

4.77e-0538994IPR011162
DomainKASH

SYNE1 SYNE2

1.66e-044992PF10541
DomainKASH

SYNE1 SYNE2

1.66e-044992IPR012315
DomainKASH

SYNE1 SYNE2

1.66e-044992PS51049
DomainKASH

SYNE1 SYNE2

1.66e-044992SM01249
DomainMHC_I

MICB ULBP2 RAET1L

1.79e-0421993PF00129
DomainMHC_I_a_a1/a2

MICB ULBP2 RAET1L

1.79e-0421993IPR001039
DomainTPR_REGION

DNAH10 PTPN23 RMDN1 TTC17 ZC3H7B CDC23

2.47e-04165996PS50293
DomainTPR

DNAH10 PTPN23 RMDN1 TTC17 ZC3H7B CDC23

2.47e-04165996PS50005
Domain-

MICB ULBP2 RAET1L

2.70e-04249933.30.500.10
DomainMHC_I-like_Ag-recog

MICB ULBP2 RAET1L

2.70e-0424993IPR011161
DomainFATC

MTOR ATM

2.75e-045992PF02260
DomainIP_trans

PITPNA PITPNB

2.75e-045992PF02121
DomainPI_transfer

PITPNA PITPNB

4.11e-046992IPR001666
DomainFAT

MTOR ATM

4.11e-046992PS51189
DomainFATC

MTOR ATM

4.11e-046992PS51190
DomainFAT

MTOR ATM

4.11e-046992PF02259
DomainPIK-rel_kinase_FAT

MTOR ATM

4.11e-046992IPR003151
DomainFATC_dom

MTOR ATM

4.11e-046992IPR003152
DomainPIK_FAT

MTOR ATM

4.11e-046992IPR014009
DomainFATC

MTOR ATM

4.11e-046992SM01343
DomainSpectrin_repeat

SYNE1 MCF2 SYNE2

4.78e-0429993IPR002017
DomainP-loop_NTPase

DNAH10 MYO5B GIMAP2 LSG1 ABCC9 SMARCAD1 KATNAL1 NLRP2 KIF3B DQX1 RAB39A DNAH11 NLRP5

5.31e-048489913IPR027417
DomainSpectrin/alpha-actinin

SYNE1 MCF2 SYNE2

6.41e-0432993IPR018159
DomainSPEC

SYNE1 MCF2 SYNE2

6.41e-0432993SM00150
DomainDHC_N1

DNAH10 DNAH11

7.63e-048992PF08385
DomainDynein_heavy_dom-1

DNAH10 DNAH11

7.63e-048992IPR013594
DomainDOCK_C

DOCK1 DOCK10

1.48e-0311992IPR010703
DomainDHR-1_domain

DOCK1 DOCK10

1.48e-0311992IPR027007
DomainDHR_2

DOCK1 DOCK10

1.48e-0311992PS51651
DomainDHR_1

DOCK1 DOCK10

1.48e-0311992PS51650
DomainDOCK-C2

DOCK1 DOCK10

1.48e-0311992PF14429
DomainDHR-2

DOCK1 DOCK10

1.48e-0311992IPR027357
DomainDHR-2

DOCK1 DOCK10

1.48e-0311992PF06920
DomainDOCK

DOCK1 DOCK10

1.48e-0311992IPR026791
DomainGalactose-bd-like

LAMA2 CUL7 F5 NGLY1

1.57e-0394994IPR008979
Domainfn3

NCAM1 PTPRZ1 CDON MYBPC1 MYBPC3

1.71e-03162995PF00041
DomainARM-type_fold

DOCK1 ARFGEF2 CUL7 MTOR ATM WDFY3 PPP6R2

2.18e-03339997IPR016024
DomainDynein_heavy_chain_D4_dom

DNAH10 DNAH11

2.43e-0314992IPR024317
DomainDynein_HC_stalk

DNAH10 DNAH11

2.43e-0314992IPR024743
DomainDynein_heavy_dom-2

DNAH10 DNAH11

2.43e-0314992IPR013602
DomainDHC_N2

DNAH10 DNAH11

2.43e-0314992PF08393
DomainMT

DNAH10 DNAH11

2.43e-0314992PF12777
DomainAAA_8

DNAH10 DNAH11

2.43e-0314992PF12780
DomainATPase_dyneun-rel_AAA

DNAH10 DNAH11

2.43e-0314992IPR011704
DomainAAA_5

DNAH10 DNAH11

2.43e-0314992PF07728
DomainDHC_fam

DNAH10 DNAH11

2.79e-0315992IPR026983
DomainDynein_heavy_dom

DNAH10 DNAH11

2.79e-0315992IPR004273
DomainDynein_heavy

DNAH10 DNAH11

2.79e-0315992PF03028
DomainPI3/4_kinase_CS

MTOR ATM

2.79e-0315992IPR018936
DomainTPR_8

TTC17 ZC3H7B CDC23

2.79e-0353993PF13181
DomainFN3

NCAM1 PTPRZ1 CDON MYBPC1 MYBPC3

3.05e-03185995SM00060
DomainARM-like

DOCK10 ARFGEF2 CUL7 MTOR WDFY3 PPP6R2

3.15e-03270996IPR011989
Domain-

MTOR ATM

3.18e-03169921.10.1070.11
DomainPI3Kc

MTOR ATM

3.18e-0316992SM00146
DomainIg_I-set

NCAM1 LRIG1 CDON MYBPC1 MYBPC3

3.42e-03190995IPR013098
DomainI-set

NCAM1 LRIG1 CDON MYBPC1 MYBPC3

3.42e-03190995PF07679
DomainPTPc_motif

DUSP4 PTPN23 PTPRZ1

3.79e-0359993SM00404
DomainTyr_Pase_cat

DUSP4 PTPN23 PTPRZ1

3.79e-0359993IPR003595
DomainIG_MHC

HLA-DPA1 ULBP2 RAET1L

3.97e-0360993PS00290
DomainPI3/4_kinase_cat_dom

MTOR ATM

4.03e-0318992IPR000403
DomainPI3_PI4_kinase

MTOR ATM

4.03e-0318992PF00454
DomainPI3_4_KINASE_3

MTOR ATM

4.03e-0318992PS50290
DomainPI3_4_KINASE_1

MTOR ATM

4.03e-0318992PS00915
DomainPI3_4_KINASE_2

MTOR ATM

4.03e-0318992PS00916
DomainFN3

NCAM1 PTPRZ1 CDON MYBPC1 MYBPC3

4.16e-03199995PS50853
Domain-

MTOR RMDN1 TTC17 ZC3H7B CDC23

4.91e-032079951.25.40.10
DomainCH

SYNE1 LMO7 SYNE2

4.97e-0365993SM00033
DomainFN3_dom

NCAM1 PTPRZ1 CDON MYBPC1 MYBPC3

5.11e-03209995IPR003961
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_RETROGRADE_AXONAL_TRANSPORT

DNAH10 DNAI1 DNAH17 DNAH11

1.53e-0527804M47755
PathwayWP_OVARIAN_INFERTILITY

NCOR1 MTOR SYNE2 ATM

6.80e-0539804M39458
PathwayKEGG_MEDICUS_REFERENCE_RETROGRADE_AXONAL_TRANSPORT

DNAH10 DNAI1 DNAH17 DNAH11

1.00e-0443804M47669
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_RETROGRADE_AXONAL_TRANSPORT

DNAH10 DNAI1 DNAH17 DNAH11

1.20e-0445804M47670
Pubmed

SUN1/2 and Syne/Nesprin-1/2 complexes connect centrosome to the nucleus during neurogenesis and neuronal migration in mice.

CALB1 SYNE1 DNAI1 SYNE2

7.10e-0814103419874786
Pubmed

Differential expression of C-protein isoforms in developing and degenerating mouse striated muscles.

LAMA2 MYBPC1 MYBPC3

2.51e-075103310024132
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ARHGAP32 TBC1D9B MYO5B PTDSS1 PTPN23 CUL7 THOC5 CEP72 SGPL1 DNAH17 PPP6R2

2.57e-074931031115368895
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

ARHGAP32 PDPR MYO5B DUSP4 PTPN23 CUL7 NCOR1 WASHC5 CEP72 PTPRZ1 UBTF SVIL SYNE2 PPME1 PPP6R2

4.83e-0710491031527880917
Pubmed

Retinoic acid early inducible genes define a ligand family for the activating NKG2D receptor in mice.

MICB ULBP2 RAET1L

5.01e-076103310894171
Pubmed

CFAP45 deficiency causes situs abnormalities and asthenospermia by disrupting an axonemal adenine nucleotide homeostasis module.

DNAI1 DNAH17 DNAH11

8.75e-077103333139725
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

ARHGAP32 MYO5B SYNE1 PTDSS1 ARFGEF2 NCAM1 ITGA2 LDHB FARSA LRIG1 LMO7 WASHC5 PTPRZ1 SGPL1 SVIL PPP6R2 DNAH11

1.02e-0614311031737142655
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

SYNE1 DOCK10 PTPN23 LMO7 CEP72 SYNE2 WDFY3

5.05e-06225103712168954
Pubmed

Molecular diversity of myofibrillar proteins: gene regulation and functional significance.

NEB MYBPC1 MYBPC3

5.44e-061210338618961
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

ARHGAP32 LSG1 SYNE1 NCAM1 NCOR1 FARSA KIF3B MTOR SVIL SYNE2 SMARCC1 WDFY3 PPP6R2

5.57e-069631031328671696
Pubmed

KASH protein Syne-2/Nesprin-2 and SUN proteins SUN1/2 mediate nuclear migration during mammalian retinal development.

SYNE1 DNAI1 SYNE2

7.06e-0613103321177258
Pubmed

A novel missense mutation in the myosin binding protein-C gene is responsible for hypertrophic cardiomyopathy with left ventricular dysfunction and dilation in elderly patients.

MYBPC1 MYBPC3

8.69e-062103212628722
Pubmed

Nesprins: a novel family of spectrin-repeat-containing proteins that localize to the nuclear membrane in multiple tissues.

SYNE1 SYNE2

8.69e-062103211792814
Pubmed

Biochemical and biological functions of class I phosphatidylinositol transfer proteins.

PITPNA PITPNB

8.69e-062103217490911
Pubmed

Nesprin-1 and nesprin-2 regulate endothelial cell shape and migration.

SYNE1 SYNE2

8.69e-062103224931616
Pubmed

Specific and nonspecific membrane-binding determinants cooperate in targeting phosphatidylinositol transfer protein beta-isoform to the mammalian trans-Golgi network.

PITPNA PITPNB

8.69e-062103216540520
Pubmed

Structure of PITPbeta in complex with phosphatidylcholine: comparison of structure and lipid transfer to other PITP isoforms.

PITPNA PITPNB

8.69e-062103216274224
Pubmed

Genetic ablation of phosphatidylinositol transfer protein function in murine embryonic stem cells.

PITPNA PITPNB

8.69e-062103211907258
Pubmed

Dynamics of lipid transfer by phosphatidylinositol transfer proteins in cells.

PITPNA PITPNB

8.69e-062103218636990
Pubmed

An ataxia-telangiectasia-mutated (ATM) kinase mediated response to DNA damage down-regulates the mRNA-binding potential of THOC5.

THOC5 ATM

8.69e-062103221937706
Pubmed

An isoform of the phosphatidylinositol-transfer protein transfers sphingomyelin and is associated with the Golgi system.

PITPNA PITPNB

8.69e-06210327654206
Pubmed

Multiple novel nesprin-1 and nesprin-2 variants act as versatile tissue-specific intracellular scaffolds.

SYNE1 SYNE2

8.69e-062103222768332
Pubmed

Rapamycin attenuates endothelial apoptosis induced by low shear stress via mTOR and sestrin1 related redox regulation.

SESN1 MTOR

8.69e-062103224587596
Pubmed

Biological functions of phosphatidylinositol transfer proteins.

PITPNA PITPNB

8.69e-062103215052341
Pubmed

Syne-1 and Syne-2 play crucial roles in myonuclear anchorage and motor neuron innervation.

SYNE1 SYNE2

8.69e-062103217267447
Pubmed

Nesprins: tissue-specific expression of epsilon and other short isoforms.

SYNE1 SYNE2

8.69e-062103224718612
Pubmed

RNA editing enzyme APOBEC3A promotes pro-inflammatory M1 macrophage polarization.

THOC5 APOBEC3A

8.69e-062103233483601
Pubmed

Targeted ablation of nesprin 1 and nesprin 2 from murine myocardium results in cardiomyopathy, altered nuclear morphology and inhibition of the biomechanical gene response.

SYNE1 SYNE2

8.69e-062103224586179
Pubmed

Archvillin anchors in the Z-line of skeletal muscle via the nebulin C-terminus.

NEB SVIL

8.69e-062103218639526
Pubmed

Cloning and expression of human cDNA encoding phosphatidylinositol transfer protein beta.

PITPNA PITPNB

8.69e-06210328541325
Pubmed

Phospholipid transfer proteins.

PITPNA PITPNB

8.69e-06210321883207
Pubmed

Lactate dehydrogenase B is critical for hyperactive mTOR-mediated tumorigenesis.

LDHB MTOR

8.69e-062103221199794
Pubmed

Nesprin-1 and -2 are involved in the pathogenesis of Emery Dreifuss muscular dystrophy and are critical for nuclear envelope integrity.

SYNE1 SYNE2

8.69e-062103217761684
Pubmed

Nesprin-1-alpha2 associates with kinesin at myotube outer nuclear membranes, but is restricted to neuromuscular junction nuclei in adult muscle.

SYNE1 SYNE2

8.69e-062103231578382
Pubmed

ATM-dependent nuclear accumulation of IKK-alpha plays an important role in the regulation of p73-mediated apoptosis in response to cisplatin.

CHUK ATM

8.69e-062103217700524
Pubmed

Mutations in NLRP2 and NLRP5 cause female infertility characterised by early embryonic arrest.

NLRP2 NLRP5

8.69e-062103230877238
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH10 DNAH17 DNAH11

8.97e-061410339373155
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

FOXM1 CDK11A SMARCAD1 CUL7 LDHB NCOR1 FARSA LMO7 PPP6R2 CDC23

1.02e-055881031038580884
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

FOXM1 ARFGEF2 CDK11A SMARCAD1 NCOR1 ZNF592 LMO7 SVIL SMARCC1 ATM CDC23

1.92e-057741031115302935
Pubmed

Specification of a Foxj1-dependent lineage in the forebrain is required for embryonic-to-postnatal transition of neurogenesis in the olfactory bulb.

CALB1 NCAM1 DNAI1

1.99e-0518103321697387
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

MYO5B LSG1 SYNE1 CAGE1 NEB CHUK NCOR1 LMO7 GCLC SYNE2 SMARCC1 ATM NGLY1 MYBPC1 BAHCC1

2.27e-0514421031535575683
Pubmed

VCP phosphorylation-dependent interaction partners prevent apoptosis in Helicobacter pylori-infected gastric epithelial cells.

TBC1D9B ARFGEF2 PTPN23 CUL7 LRIG1 MTOR SMARCC1

2.50e-05288103723383273
Pubmed

mTOR-dependent regulation of ribosomal gene transcription requires S6K1 and is mediated by phosphorylation of the carboxy-terminal activation domain of the nucleolar transcription factor UBF.

MTOR UBTF

2.60e-053103214612424
Pubmed

Increased BUB1B/BUBR1 expression contributes to aberrant DNA repair activity leading to resistance to DNA-damaging agents.

FOXM1 ATM

2.60e-053103234545188
Pubmed

The prognostic significance of soluble NKG2D ligands in B-cell chronic lymphocytic leukemia.

MICB ULBP2

2.60e-053103220428196
Pubmed

Clinical significance of the NKG2D ligands, MICA/B and ULBP2 in ovarian cancer: high expression of ULBP2 is an indicator of poor prognosis.

MICB ULBP2

2.60e-053103218791713
Pubmed

The anti-apoptotic activity associated with phosphatidylinositol transfer protein alpha activates the MAPK and Akt/PKB pathway.

PITPNA PITPNB

2.60e-053103218501717
Pubmed

[Occurrence of plasmic and platelet prothrombotic polymorphisms in women in childbirth].

ITGA2 F5

2.60e-053103216875034
Pubmed

The inner nuclear membrane protein Sun1 mediates the anchorage of Nesprin-2 to the nuclear envelope.

SYNE1 SYNE2

2.60e-053103216079285
Pubmed

Abnormal development of Purkinje cells and lymphocytes in Atm mutant mice.

CALB1 ATM

2.60e-053103210716718
Pubmed

Defects in ciliary localization of Nek8 is associated with cystogenesis.

CALB1 NCAM1

2.60e-053103218189147
Pubmed

[P53-independent apoptosis through a novel ATM/IKK-alpha/p73-mediated apoptotic pathway].

CHUK ATM

2.60e-053103218575226
Pubmed

Akt-dependent activation of mTORC1 complex involves phosphorylation of mTOR (mammalian target of rapamycin) by IκB kinase α (IKKα).

CHUK MTOR

2.60e-053103224990947
Pubmed

Further studies on cortical tangential migration in wild type and Pax-6 mutant mice.

CALB1 NCAM1

2.60e-053103214501209
Pubmed

Phosphatidylinositol transfer proteins regulate megakaryocyte TGF-β1 secretion and hematopoiesis in mice.

PITPNA PITPNB

2.60e-053103230042096
Pubmed

Targeting the NF-κB and mTOR pathways with a quinoxaline urea analog that inhibits IKKβ for pancreas cancer therapy.

CHUK MTOR

2.60e-053103223444213
Pubmed

Human cytomegalovirus glycoprotein UL16 causes intracellular sequestration of NKG2D ligands, protecting against natural killer cell cytotoxicity.

MICB ULBP2

2.60e-053103212782710
Pubmed

Syne-1, a dystrophin- and Klarsicht-related protein associated with synaptic nuclei at the neuromuscular junction.

SYNE1 SYNE2

2.60e-053103210878022
Pubmed

ATM and p53 regulate FOXM1 expression via E2F in breast cancer epirubicin treatment and resistance.

FOXM1 ATM

2.60e-053103221518729
Pubmed

ATM protein physically and functionally interacts with proliferating cell nuclear antigen to regulate DNA synthesis.

MTOR ATM

2.60e-053103222362778
Pubmed

Human anaplastic thyroid carcinoma cells are sensitive to NK cell-mediated lysis via ULBP2/5/6 and chemoattract NK cells.

ULBP2 RAET1L

2.60e-053103225212604
Pubmed

Vesicular stomatitis virus infection promotes immune evasion by preventing NKG2D-ligand surface expression.

MICB ULBP2

2.60e-053103221857986
Pubmed

Circular RNA circCCDC66 promotes glioma proliferation by acting as a ceRNA for miR-320a to regulate FOXM1 expression.

FOXM1 CCDC66

2.60e-053103234252882
Pubmed

The nesprins are giant actin-binding proteins, orthologous to Drosophila melanogaster muscle protein MSP-300.

SYNE1 SYNE2

2.60e-053103212408964
Pubmed

The RNA binding protein IMP3 facilitates tumor immune escape by downregulating the stress-induced ligands ULPB2 and MICB.

MICB ULBP2

2.60e-053103226982091
Pubmed

Aberrant cytoplasmic localization of N-CoR in colorectal tumors.

CHUK NCOR1

2.60e-053103217630505
Pubmed

Distinct functional domains in nesprin-1alpha and nesprin-2beta bind directly to emerin and both interactions are disrupted in X-linked Emery-Dreifuss muscular dystrophy.

SYNE1 SYNE2

2.60e-053103217462627
Pubmed

Aberrant CD8+ T-cell responses and memory differentiation upon viral infection of an ataxia-telangiectasia mouse model driven by hyper-activated Akt and mTORC1 signaling.

MTOR ATM

2.60e-053103221641396
Pubmed

Structures of FHOD1-Nesprin1/2 complexes reveal alternate binding modes for the FH3 domain of formins.

SYNE1 SYNE2

2.60e-053103233472039
Pubmed

ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS.

MTOR ATM

2.60e-053103220160076
Pubmed

Nesprins anchor kinesin-1 motors to the nucleus to drive nuclear distribution in muscle cells.

SYNE1 SYNE2

2.60e-053103225516977
Pubmed

Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex.

C11orf54 CHUK GCLC WASHC5 MTOR TTC17 MYBPC3

3.52e-05304103732235678
Pubmed

Direct interaction of the mouse cytomegalovirus m152/gp40 immunoevasin with RAE-1 isoforms.

ULBP2 RAET1L

5.19e-054103220166740
Pubmed

SUN1 interacts with nuclear lamin A and cytoplasmic nesprins to provide a physical connection between the nuclear lamina and the cytoskeleton.

SYNE1 SYNE2

5.19e-054103216648470
Pubmed

Differential involvement of IkappaB kinases alpha and beta in cytokine- and insulin-induced mammalian target of rapamycin activation determined by Akt.

CHUK MTOR

5.19e-054103218490760
Pubmed

Left-right development: the roles of nodal cilia.

KIF3B DNAH11

5.19e-054103210704402
Pubmed

FOXM1-regulated ZIC2 promotes the malignant phenotype of renal clear cell carcinoma by activating UBE2C/mTOR signaling pathway.

FOXM1 MTOR

5.19e-054103237496990
Pubmed

A potential role for the OTX2 homeoprotein in creating early 'highways' for axon extension in the rostral brain.

NCAM1 PTPRZ1

5.19e-05410329753681
Pubmed

Dynamic spatiotemporal expression patterns of neurocan and phosphacan indicate diverse roles in the developing and adult mouse olfactory system.

NCAM1 PTPRZ1

5.19e-054103210861539
Pubmed

Mutations in dynein genes in patients affected by isolated non-syndromic asthenozoospermia.

DNAI1 DNAH11

5.19e-054103218492703
Pubmed

The underlying mechanism of proinflammatory NF-κB activation by the mTORC2/Akt/IKKα pathway during skin aging.

CHUK MTOR

5.19e-054103227486771
Pubmed

Sumoylation of PPARγ contributes to vascular endothelium insulin resistance through stabilizing the PPARγ-NcoR complex.

CHUK NCOR1

5.19e-054103230982983
Pubmed

Structure of a multifunctional protein. Mammalian phosphatidylinositol transfer protein complexed with phosphatidylcholine.

PITPNA PITPNB

5.19e-054103211104777
Pubmed

Outer nuclear membrane protein Kuduk modulates the LINC complex and nuclear envelope architecture.

SYNE1 SYNE2

5.19e-054103228716842
Pubmed

The laminin alpha2-chain short arm mediates cell adhesion through both the alpha1beta1 and alpha2beta1 integrins.

LAMA2 ITGA2

5.19e-05410329361014
Pubmed

Cloning and characterization of a novel human phosphatidylinositol transfer protein, rdgBbeta.

PITPNA PITPNB

5.19e-054103210531358
Pubmed

Differential role of planar cell polarity gene Vangl2 in embryonic and adult mammalian kidneys.

CALB1 NCAM1

5.19e-054103232203543
Pubmed

Soluble ligands for the NKG2D receptor are released during endometriosis and correlate with disease severity.

MICB ULBP2

5.19e-054103225775242
Pubmed

Mammalian target of rapamycin (mTOR) inhibition with rapamycin improves cardiac function in type 2 diabetic mice: potential role of attenuated oxidative stress and altered contractile protein expression.

MTOR MYBPC3

5.19e-054103224371138
Pubmed

Molecular motors: the driving force behind mammalian left-right development.

KIF3B DNAH11

5.19e-054103210652513
Pubmed

mTORC1 signaling under hypoxic conditions is controlled by ATM-dependent phosphorylation of HIF-1α.

MTOR ATM

5.19e-054103221095582
Pubmed

LINC complexes mediate the positioning of cone photoreceptor nuclei in mouse retina.

SYNE1 SYNE2

5.19e-054103223071752
Pubmed

Isolation and characterization of retinoic acid-inducible cDNA clones in F9 cells: a novel cDNA family encodes cell surface proteins sharing partial homology with MHC class I molecules.

ULBP2 RAET1L

5.19e-05410328882725
Pubmed

Upregulation of Neural Cell Adhesion Molecule 1 and Excessive Migration of Purkinje Cells in Cerebellar Cortex.

CALB1 NCAM1

5.19e-054103235126044
Pubmed

Oxamate-mediated inhibition of lactate dehydrogenase induces protective autophagy in gastric cancer cells: involvement of the Akt-mTOR signaling pathway.

LDHB MTOR

5.19e-054103225524555
Pubmed

Nesprins, but not sun proteins, switch isoforms at the nuclear envelope during muscle development.

SYNE1 SYNE2

5.19e-054103220108321
Pubmed

Cutting edge: tumor rejection mediated by NKG2D receptor-ligand interaction is dependent upon perforin.

ULBP2 RAET1L

5.19e-054103212421908
Pubmed

Tenascin-C is an inhibitory boundary molecule in the developing olfactory bulb.

NCAM1 PTPRZ1

5.19e-054103219641104
Pubmed

NKG2D-mediated natural killer cell protection against cytomegalovirus is impaired by viral gp40 modulation of retinoic acid early inducible 1 gene molecules.

ULBP2 RAET1L

5.19e-054103212756263
Pubmed

Mild hypoxia in vivo regulates cardioprotective SUR2A: A role for Akt and LDH.

ABCC9 LDHB

5.19e-054103225576887
GeneFamilyDyneins, axonemal

DNAH10 DNAI1 DNAH17 DNAH11

4.45e-0717694536
GeneFamilySpectrin repeat containing nuclear envelope family

SYNE1 SYNE2

8.57e-0546921252
GeneFamilyPhosphatidylinositol transfer proteins

PITPNA PITPNB

2.13e-0466921151
GeneFamilyFibronectin type III domain containing

NCAM1 PTPRZ1 CDON MYBPC1 MYBPC3

3.63e-04160695555
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

NCAM1 LRIG1 CDON MYBPC1 MYBPC3

3.73e-04161695593
GeneFamilyFibronectin type III domain containing|I-set domain containing|Myosin binding proteins

MYBPC1 MYBPC3

3.96e-048692658
GeneFamilyPolypeptide N-acetylgalactosaminyltransferases

GALNT18 GALNT9

2.61e-0320692433
GeneFamilyNLR family

NLRP2 NLRP5

4.07e-0325692666
GeneFamilyPyrin domain containing|Pyrin and HIN domain family

NLRP2 NLRP5

4.07e-0325692994
CoexpressionEIF4E_DN

DOCK1 ARHGAP32 LMO7 WASHC5 SVIL WDFY3

2.81e-061001036M2790
ToppCellIPF-Multiplet-Multiplet|IPF / Disease state, Lineage and Cell class

DNAH10 SYNE1 GALNT18 DNAI1 LRIG1 LMO7 SYNE2 DNAH11

1.80e-081951038fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCellIPF-Multiplet|IPF / Disease state, Lineage and Cell class

DNAH10 SYNE1 GALNT18 DNAI1 LRIG1 LMO7 SYNE2 DNAH11

1.80e-081951038eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCellTCGA-Uvea-Primary_Tumor-Uveal_Melanoma-Epithelioid_Cell|TCGA-Uvea / Sample_Type by Project: Shred V9

PTDSS1 ITGA2 GALNT18 WASHC5 SGPL1 CDC23

4.72e-061861036e8580a2093eb7e50aad55ec7fada850d2fed8ae1
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DUSP4 F5 LDHB CCDC66 LRIG1 SYNE2

5.02e-0618810369db3d3010cb8a1f3ee1cdccaf3cbaac3cf983fc5
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

DUSP4 F5 LDHB CCDC66 LRIG1 SYNE2

5.02e-06188103672be6fe654f3a5f654d3b9680145bce7ae9b721d
ToppCellCOVID-19_Mild-Lymphoid_T/NK-Treg|COVID-19_Mild / Disease group, lineage and cell class

DUSP4 F5 LDHB CCDC66 LRIG1 SYNE2

5.02e-06188103642553fdc127e5f613ffd5067620a768a40f1a8a1
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C11orf54 SMARCAD1 NCOR1 UBTF SYNE2 PITPNA

5.50e-06191103660c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C11orf54 SMARCAD1 NCOR1 UBTF SYNE2 PITPNA

5.50e-061911036973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH10 ITGA2 DNAI1 LRIG1 PTPRZ1 DNAH11

5.83e-061931036ea345d34440b25f65358a53dc72831998d1c3620
ToppCellCOPD-Multiplet-Multiplet|COPD / Disease state, Lineage and Cell class

SYNE1 GALNT18 DNAI1 LMO7 SYNE2 DNAH11

6.37e-061961036af4cdc61830685a888a1209826c23bcf54a43084
ToppCellCOPD-Multiplet|COPD / Disease state, Lineage and Cell class

SYNE1 GALNT18 DNAI1 LMO7 SYNE2 DNAH11

6.37e-0619610366d02d494196e3f857d53eea46d9419690d43beca
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH10 FSIP1 SYNE1 SYNE2 GRIN3B DNAH11

6.56e-06197103674a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCellBronchial_Biopsy-Epithelial|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

ITGA2 LDHB LMO7 GCLC PTPRZ1 SYNE2

6.95e-061991036ef5d8917c8d011184830a0b8197afc6266707b37
ToppCellcontrol|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ARHGAP32 ITGA2 LRIG1 LMO7 PTPRZ1 SYNE2

7.15e-06200103697f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-Treg|COVID-19_Mild / Disease, condition lineage and cell class

DUSP4 F5 LDHB CCDC66 LRIG1 SYNE2

7.15e-062001036c6ae15f7deba26008af5b647855675003bb2ebcd
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Mesenchymal-Mesoderm|6m / Sample Type, Dataset, Time_group, and Cell type.

ABCC9 NEB LMO7 AGL SVIL MYBPC1

7.15e-0620010360f6851baf0cf2a8b0c95a7a585c4407c330c5f6c
ToppCellControl-Epithelial_alveolar-Mes-Like|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH10 MYO5B LMO7 PTPRZ1 FBXO39

7.47e-061161035df7609503782d8d7e4f31ed2a626916e5474d5bc
ToppCell3'_v3-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8|bone_marrow / Manually curated celltypes from each tissue

SYNE1 DUSP4 SYNE2 SPATA22 ATM

9.18e-06121103519333a660800b583fa27b495c1f7828e6636a257
ToppCellLPS_only-Epithelial_alveolar-AT_2-Differentiating_AT1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYO5B ITGA2 LMO7 SYNE2 NLRP5

1.16e-0512710355b0adbcafad31a6759c9bdce2f7f9591a8edc450
ToppCellControl-Epithelial_alveolar-Mes-Like-Differentiating_AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH10 MYO5B PTPRZ1 FBXO39 CDON

1.16e-051271035556aaf88719c83f307fa50dfac151136ed05c8ad
ToppCell343B-Myeloid-Macrophage-SPP1+_Macrophage_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

LAMA2 CCDC122 CEP72 MICB PPP6R2

2.59e-051501035744050a1b665c6989f37141348af3df7579a73c9
ToppCellmild_COVID-19_(asymptomatic)-NK_CD56bright|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

DUSP4 NCAM1 NEB NLRP2 FSIP2

2.68e-0515110352470162f4b56bc505db166a6eb0fa54847759df8
ToppCell10x5'-Lung-Lymphocytic_T_CD4-Tregs|Lung / Manually curated celltypes from each tissue

DUSP4 F5 LDHB GALNT18 LRIG1

3.33e-051581035f433bc189f000efa34e8e09ab32b3fa22bcf64c4
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig-Z|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GIMAP2 SYNE1 ABCC9 SYNE2 ATM

3.43e-051591035bf8ff9251bcb64b2b9d6dd93461aec97659686ec
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg-Treg_0|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DUSP4 F5 LDHB LRIG1 SYNE2

3.43e-0515910356599707107083af6da092fe8984afc8fd89d2bb8
ToppCell368C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|368C / Donor, Lineage, Cell class and subclass (all cells)

FSIP1 GIMAP2 DUSP4 KATNAL1 CCDC66

3.43e-0515910357065062fce248e0458932a22dfcc25a5b5a70cbd
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg-Treg_0|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

DUSP4 F5 LDHB LRIG1 SYNE2

3.43e-051591035916d070d099726f22deb71966efccff00f8ea071
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Myeloid-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO5B ABCC9 ZNF592 SGPL1 PPP6R2

3.75e-051621035b502d6af6868425b5c919740e011330c0d3cf3b8
ToppCellCOVID-19_Moderate-Treg|COVID-19_Moderate / disease group, cell group and cell class

DUSP4 F5 LDHB LRIG1 SYNE2

4.33e-0516710354ddb21421cbe72c06b61dd3a5eb1337e59de42e5
ToppCellmild_COVID-19-Treg|World / disease group, cell group and cell class (v2)

DUSP4 LDHB CCDC66 LRIG1 SYNE2

4.33e-05167103569330689b6e353c8ee9ea1b63a5eac6ab38d456f
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-CD4-positive,_alpha-beta_T_cell-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

CALB1 DOCK10 LDHB SYNE2 ATM

4.46e-0516810355e721268f0baa51d3f640f7f4c41db769ebef210
ToppCellCOVID-19_Moderate-Treg|World / disease group, cell group and cell class

DUSP4 F5 LDHB LRIG1 SYNE2

4.58e-05169103527ad11239559b025bef582f89b2a83501d9d3993
ToppCellT_cells-GNLY+GZMB+_T_cells|T_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

SGSM1 CALB1 SYNE1 NCAM1 SPATA22

4.85e-05171103504c811817cfec45af5f2891793106cc7ddb0300e
ToppCellmild_COVID-19-Treg|mild_COVID-19 / disease group, cell group and cell class (v2)

DUSP4 F5 LDHB CCDC66 SYNE2

4.98e-05172103577af6324c06b67867e7ce07706536fe38de5ed7b
ToppCell11.5-Airway-Epithelial-Basal_cell|Airway / Age, Tissue, Lineage and Cell class

CAGE1 ITGA2 LMO7 PTPRZ1 GJB7

4.98e-0517210359d4d92e2d16dfc8a394f2641653bb97de20a2530
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C16orf96 LDHB DNAI1 ATP6V1C2 MYBPC1

4.98e-051721035e15ab284df6dd241d4481f98864b18c39d757b8c
ToppCellHealthy_donor-Treg|World / disease group, cell group and cell class (v2)

DUSP4 F5 LDHB CCDC66 SYNE2

5.26e-051741035dc3b06420b0ad9c7060571e7bf5714e028d598bf
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 GALNT18 DNAH17 WDFY3 DNAH11

5.56e-051761035327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-nan|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C11orf54 ITGA2 LDHB FABP2 GCLC

5.56e-0517610351dd54bfaa58541de51e5a8328651d390833bd480
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK-T_mait|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SYNE1 SESN1 SYNE2 ATM GJB7

5.56e-051761035003076f1a983409ddf31b9c19e61c1facdd72566
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c12-FOXP3|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DUSP4 F5 LDHB LRIG1 SYNE2

6.18e-0518010356bb9f41c3a99d1bbe697f589fb2bcea9b7bfbeee
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXM1 SYNE1 NCAM1 F5 SYNE2

6.34e-051811035566249e04dd491e6287ad2101b7b1ab11031ed8b
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXM1 SYNE1 NCAM1 F5 SYNE2

6.34e-051811035db9528dc7cb0230e4c36cb27da69102c588c7ee9
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_0|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

DUSP4 F5 LDHB LRIG1 SYNE2

6.86e-051841035300edc4aa3ce55f309005c02c315fa0102ea9da7
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c12-FOXP3|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DUSP4 LDHB CCDC66 LRIG1 SYNE2

6.86e-05184103508bff25390e3484b75c860738396a405141b69fd
ToppCellLV-15._Ventricular_Cardiomyocyte_III|LV / Chamber and Cluster_Paper

LAMA2 NCAM1 LMO7 SVIL MYBPC3

6.86e-051841035ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_0|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DUSP4 F5 LDHB LRIG1 SYNE2

6.86e-0518410358b397f9c18ed7abecdbcbd586d0ddadf07cf6e75
ToppCell10x5'-blood-Lymphocytic_T_CD4-Tregs|blood / Manually curated celltypes from each tissue

DUSP4 F5 LDHB LRIG1 SYNE2

6.86e-05184103522c15ce30171c687ab564f4383ae74d38b759272
ToppCelldroplet-Bladder-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA2 LDHB NCOR1 GCLC SYNE2

7.40e-051871035663991a8afe652e92363b64bcbd68c14d0307f0e
ToppCell(1)_T_CD4_naive|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

LDHB CCDC66 LMO7 SYNE2 ATM

7.59e-051881035b8f67ac2faadd5b848955e43ab5d6cf5e49b3681
ToppCellCiliated_cells-B-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

DNAH10 DNAI1 GCLC GRIN3B DNAH11

7.59e-051881035606907c865bd2f11bb6474932716550f7723d858
ToppCellRV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

LAMA2 NCAM1 LMO7 SVIL MYBPC3

7.78e-0518910355e80c47f63980904c4c1ff02c201b67b456a0974
ToppCellrenal_medulla_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK1 SYNE1 GALNT18 LMO7 WDFY3

7.78e-051891035830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma|TCGA-Lung / Sample_Type by Project: Shred V9

LSG1 PTDSS1 DQX1 PTPRZ1 RAET1L

7.78e-051891035aa4f7d7a5196e5ae481ebc2549de8e3f0ef6e6be
ToppCellnormal_Pleural_Fluid-T/NK_cells-Treg|normal_Pleural_Fluid / Location, Cell class and cell subclass

DUSP4 F5 LDHB CCDC66 SYNE2

7.98e-051901035632b9541371483d25948b6f033863c49f38e3603
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.4.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SYNE1 DOCK10 NCAM1 SYNE2 ATM

7.98e-051901035d153a0bdedcd6865e6ee19575234a78b5d859ff1
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

USP25 GALNT18 SGPL1 GALNT9 DNAH17

7.98e-05190103559bbbd2c8d4b7ce46c54ca8022b1557e7e5eee2a
ToppCellRV-06._Ventricular_Cardiomyocyte_II|RV / Chamber and Cluster_Paper

LAMA2 NCAM1 LMO7 SVIL MYBPC3

7.98e-051901035fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCellLV-06._Ventricular_Cardiomyocyte_II|LV / Chamber and Cluster_Paper

LAMA2 NCAM1 LMO7 SVIL MYBPC3

8.18e-05191103525f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCellfacs-Lung-Endomucin_-18m-Endothelial-Capillary_Aerocyte_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCAM1 ITGA2 DNAI1 LMO7 DNAH11

8.18e-051911035df8cdbc26443e55a203cbafa21b0952a2a55b9bf
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C11orf54 NCOR1 UBTF SYNE2 PITPNA

8.18e-05191103509db184cb90fe282a14474d7217068c58092c6f8
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4-Tregs|lymph-node_spleen / Manually curated celltypes from each tissue

DUSP4 F5 LDHB LRIG1 SYNE2

8.38e-05192103504bd6e135733570e877af9460f87379ed0a5c5f8
ToppCellHealthy-Treg|Healthy / disease group, cell group and cell class

DUSP4 F5 LDHB LRIG1 SYNE2

8.38e-0519210359d3795a64bf0c62f460d80730c5615869fc46933
ToppCell3'-Broncho-tracheal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NCAM1 LDHB SMARCC1 ATP6V1C2 MYBPC1

8.59e-0519310355879efb38e6b3bf8c33c9a773632b1d726e3c153
ToppCellControl-Lymphoid_T/NK-Treg|Control / Disease group, lineage and cell class

DUSP4 F5 LDHB LRIG1 SYNE2

8.59e-051931035715f2bbee12a7952cba85d9cd8820411983ce790
ToppCell3'-Broncho-tracheal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree-Tuft|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NCAM1 LDHB SMARCC1 ATP6V1C2 MYBPC1

8.59e-051931035725115a5ce3ef520b3ef469e96b8219b4c723fdd
ToppCell3'-Broncho-tracheal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree-Tuft-Tuft_L.0.7.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NCAM1 LDHB SMARCC1 ATP6V1C2 MYBPC1

8.59e-051931035abd7bcf318a2d895d8811c2ada8bfb4314fca3b1
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 GALNT18 LMO7 SVIL SYNE2

8.80e-051941035e577d9e88390b36b5a09b97fe1026089892275a3
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

DUSP4 F5 LDHB LRIG1 SYNE2

8.80e-0519410352faf49d85d09932c9c20d9f675c8093ad802fae5
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DUSP4 F5 LDHB LRIG1 SYNE2

8.80e-051941035fd3d5ac94de3db7136684c86f8589631ad87e6d8
ToppCellCOVID-19-Heart-CM_2|Heart / Disease (COVID-19 only), tissue and cell type

LAMA2 NCAM1 LMO7 SVIL MYBPC3

9.01e-05195103575fc81bddb246dca3b437fb60827b1d4fe416405
ToppCellCOVID-19_Severe-Lymphoid_T/NK-gd_T|COVID-19_Severe / Disease group, lineage and cell class

SYNE1 LAMA2 NCAM1 SYNE2 ATM

9.01e-0519510359990440bda7fac5d00ef80444fab07459be625e1
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

SYNE1 LAMA2 NCAM1 SYNE2 ATM

9.23e-051961035418e8e0a51c5cb60e3b903e7d2d800dc8b9f3d5c
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SYNE1 LAMA2 NCAM1 SYNE2 ATM

9.23e-051961035581fc8c8d42005aacd7b401a2c9d1fc331fb4af7
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SYNE1 LAMA2 NCAM1 SYNE2 ATM

9.23e-0519610356beaf0c2799424c59819b286fbb5c1a83d85e4d1
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SYNE1 LAMA2 NCAM1 SYNE2 ATM

9.23e-051961035c35f2349dfe35baa845f790b9f31673dceac54c0
ToppCellIPF-Epithelial|IPF / Disease state, Lineage and Cell class

DNAH10 MYO5B DNAI1 LMO7 DNAH11

9.23e-05196103587d9881cfec461a5d89b688a83749b618c519485
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FOXM1 CALB1 ITGA2 PTPRZ1 RAET1L

9.46e-051971035fb272c9c60ee3d980e528044dc567b4925a23da6
ToppCell3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FOXM1 ITGA2 GCLC PTPRZ1 RAET1L

9.46e-0519710351d4ccca2ff46fccb3ac052b5148cb7f94231d65a
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FOXM1 CALB1 ITGA2 PTPRZ1 RAET1L

9.46e-05197103561c0d78b29dc4ad8a84172cbfcdab03f31351d0e
ToppCell3'-Broncho-tracheal|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ITGA2 LDHB GCLC PTPRZ1 SYNE2

9.46e-0519710355d33f8a6940431093e927b186fb9b630a89d8ec1
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_only / Treatment groups by lineage, cell group, cell type

MYO5B PTDSS1 ITGA2 SYNE2 CDON

9.46e-0519710356b6504c47c309bac4f790e2f372d454bbdea49e8
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SYNE1 LDHB SYNE2 RAB39A ATM

9.46e-051971035268ca646f4a7466709c2c8b6ca56cf1344f3ef3e
ToppCellcontrol-Treg|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

DUSP4 F5 LDHB LRIG1 SYNE2

9.46e-051971035a80674a0b996aa57d52bfff7264c57caf4c31cc6
ToppCellSepsis-ICU-SEP-Lymphocyte-T/NK-Treg|ICU-SEP / Disease, condition lineage and cell class

LDHB FSIP2 LRIG1 SYNE2 ULBP2

9.46e-051971035c3ee2d522fbfe67069ddba2d1abfc4f5ca230c26
ToppCellSigmoid-(1)_T_cell-(14)_Tcm|Sigmoid / shred on region, Cell_type, and subtype

FOXM1 GIMAP2 SYNE1 F5 MTOR

9.92e-051991035ec454fa22fb7f50a947bdf4c4bb6f0ba13f62b4c
ToppCellCaecum-(1)_T_cell-(14)_Tcm|Caecum / shred on region, Cell_type, and subtype

GIMAP2 F5 LDHB LMO7 ATM

9.92e-0519910350f89426e8dec0cbe78f6c55caaa196daf0eaf66a
ToppCellCaecum-T_cell-Tcm|Caecum / Region, Cell class and subclass

GIMAP2 F5 LDHB LMO7 ATM

9.92e-051991035cab97db995a7d7df3b8f0511139ef0fe65ee55b9
ToppCell(09)_Interm._secr.>cil.-(2)_GFP_FOXI1|(09)_Interm._secr.>cil. / shred by cell type by condition

DUSP4 ABCC9 MRPL45 LMO7 SYNE2

9.92e-051991035fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCellSepsis-Leuk-UTI-Lymphocyte-T/NK-Treg|Leuk-UTI / Disease, condition lineage and cell class

DUSP4 F5 LDHB LRIG1 SYNE2

9.92e-051991035100f45e04f284551b29ef0406476bdc347ddbf7e
ToppCellhealthy_donor-Lymphocytic|healthy_donor / Disease condition, Lineage, Cell class and subclass

SYNE1 NCAM1 LDHB SYNE2 ATM

9.92e-0519910352841e16d54acd344ba454f024e285c28abc37319
ToppCellControl-Control-Lymphocyte-T/NK-Treg|Control / Disease, condition lineage and cell class

DUSP4 F5 LDHB LRIG1 SYNE2

9.92e-0519910356b7eb14bf03aa05f2d4ac4f5dd1ccf41a7e47bd1
ToppCellSepsis-Leuk-UTI-Lymphocyte-T/NK-gd_T|Leuk-UTI / Disease, condition lineage and cell class

DNAH10 FSIP1 SYNE1 IPP SYNE2

9.92e-051991035b2c1b9ee764e1246bfa3ecf666ca76ae4ac6c362
ToppCell(03)_KRT6B+-(2)_GFP_FOXI1|(03)_KRT6B+ / shred by cell type by condition

USP25 ABCC9 NCOR1 LMO7 SYNE2

9.92e-051991035c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCellSigmoid-T_cell-Tcm|Sigmoid / Region, Cell class and subclass

FOXM1 GIMAP2 SYNE1 F5 MTOR

9.92e-051991035f7c729eaa3c8fd5a05cb6f79cac9b8f199c8092b
ToppCellHematolymphoid-Endothelial-NOSTRIN|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

DOCK1 SYNE1 LAMA2 GALNT18 SYNE2

1.02e-042001035032df80aa5c40991e1c1e80f9d8da106e6aeaee2
ToppCellHematolymphoid-Endothelial-NOSTRIN---|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

DOCK1 SYNE1 LAMA2 GALNT18 SYNE2

1.02e-04200103568fce28690246895fd33354b30960ebcc31aa4cc
ToppCellHematolymphoid-Endothelial-NOSTRIN-|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

DOCK1 SYNE1 LAMA2 GALNT18 SYNE2

1.02e-042001035376b19ab5a7cd2c85f726d8ba41337d4525863e5
ToppCellHematolymphoid-Endothelial-NOSTRIN--|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

DOCK1 SYNE1 LAMA2 GALNT18 SYNE2

1.02e-0420010357fa54370221ed61bac0e09e6bcf1f3dff202a846
ToppCellMS-Multiple_Sclerosis-Lymphocyte-T/NK-Treg|Multiple_Sclerosis / Disease, condition lineage and cell class

DUSP4 LDHB CCDC66 LRIG1 SYNE2

1.02e-0420010358702758a62fa923c2e9012c0aa8b3b492a44f8fb
Diseaselevel of UL16-binding protein 6 in blood serum

ULBP2 RAET1L

1.16e-0521012OBA_2043185
Diseasemortality

HLA-DPA1 NCAM1 MICB SVIL RAB39A PITPNB

2.98e-051731016EFO_0004352
DiseaseRetinal Vein Occlusion

ITGA2 F5

3.47e-0531012C0035328
DiseaseThrombosis of retinal vein

ITGA2 F5

3.47e-0531012C1527411
DiseaseAutosomal dominant Emery-Dreifuss muscular dystrophy

SYNE1 SYNE2

6.93e-0541012cv:CN293514
DiseaseKartagener syndrome (is_implicated_in)

DNAI1 DNAH11

6.93e-0541012DOID:0050144 (is_implicated_in)
DiseaseAutosomal Recessive Emery-Dreifuss Muscular Dystrophy

SYNE1 SYNE2

1.15e-0451012C1450051
DiseaseAutosomal Dominant Emery-Dreifuss Muscular Dystrophy (disorder)

SYNE1 SYNE2

1.15e-0451012C0410190
DiseaseConventional (Clear Cell) Renal Cell Carcinoma

CUL7 LDHB MTOR SYNE2 ATM

1.60e-041481015C0279702
DiseaseEmery-Dreifuss muscular dystrophy

SYNE1 SYNE2

1.72e-0461012cv:C0410189
DiseaseCongenital muscular dystrophy (disorder)

LAMA2 SYNE2

1.72e-0461012C0699743
DiseaseMuscular Dystrophy, Emery-Dreifuss

SYNE1 SYNE2

1.72e-0461012C0410189
Diseaseretinal vein occlusion (is_implicated_in)

ITGA2 F5

2.41e-0471012DOID:1727 (is_implicated_in)
DiseaseX-Linked Emery-Dreifuss Muscular Dystrophy

SYNE1 SYNE2

2.41e-0471012C0751337
Diseasemuscular atrophy (implicated_via_orthology)

CHUK MTOR

2.41e-0471012DOID:767 (implicated_via_orthology)
DiseaseMalignant neoplasm of breast

FOXM1 TBC1D9B SYNE1 LAMA2 ARFGEF2 LDHB THOC5 APOBEC3A NCOR1 MTOR SYNE2 ATM

3.08e-04107410112C0006142
Diseaseoctadecanedioate measurement

LAMA2 NCAM1

5.13e-04101012EFO_0021056
DiseaseEmery-Dreifuss muscular dystrophy (implicated_via_orthology)

SYNE1 SYNE2

7.49e-04121012DOID:11726 (implicated_via_orthology)
DiseaseSchizophrenia

ARHGAP32 CALB1 MYO5B LAMA2 NCAM1 GCLC MTOR PTPRZ1 MICB ATM

9.03e-0488310110C0036341
DiseaseSarcomatoid Renal Cell Carcinoma

CUL7 LDHB MTOR SYNE2

9.97e-041281014C1266043
DiseaseChromophobe Renal Cell Carcinoma

CUL7 LDHB MTOR SYNE2

9.97e-041281014C1266042
DiseaseCollecting Duct Carcinoma of the Kidney

CUL7 LDHB MTOR SYNE2

9.97e-041281014C1266044
DiseasePapillary Renal Cell Carcinoma

CUL7 LDHB MTOR SYNE2

9.97e-041281014C1306837
DiseaseRenal Cell Carcinoma

CUL7 LDHB MTOR SYNE2

9.97e-041281014C0007134
DiseaseKartagener syndrome (implicated_via_orthology)

DNAI1 DNAH11

1.03e-03141012DOID:0050144 (implicated_via_orthology)
DiseaseNeoplasm of uncertain or unknown behavior of bladder

MTOR ATM

1.18e-03151012C0496930
DiseaseBenign neoplasm of bladder

MTOR ATM

1.18e-03151012C0154017
DiseaseCarcinoma in situ of bladder

MTOR ATM

1.18e-03151012C0154091
Diseasethrombosis (is_implicated_in)

ITGA2 F5

1.18e-03151012DOID:0060903 (is_implicated_in)
DiseaseMalignant lymphoma, lymphocytic, intermediate differentiation, diffuse

MTOR ATM

1.35e-03161012C0334634
DiseaseBladder Neoplasm

LAMA2 NCOR1 MTOR ATM

1.39e-031401014C0005695
Diseasesusceptibility to hepatitis B infection measurement

MYO5B HLA-DPA1 ARFGEF2

1.39e-03641013EFO_0008405
DiseaseMalignant neoplasm of urinary bladder

LAMA2 NCOR1 MTOR ATM

1.42e-031411014C0005684
DiseaseInborn Errors of Metabolism

MYO5B LDHB

1.53e-03171012C0025521
Diseasemuscular dystrophy (is_implicated_in)

SYNE1 LAMA2

1.53e-03171012DOID:9884 (is_implicated_in)
Diseaseforced expiratory volume

SYNE1 ARFGEF2 NCOR1 KIF3B CEP72 AGL PPP6R2 CDON MYBPC1

1.56e-037891019EFO_0004314
DiseaseCarcinoma of bladder

MTOR ATM

1.71e-03181012C0699885
DiseaseMammary Carcinoma, Human

FOXM1 SYNE1 LDHB APOBEC3A NCOR1 MTOR ATM

2.21e-035251017C4704874
DiseaseMammary Neoplasms, Human

FOXM1 SYNE1 LDHB APOBEC3A NCOR1 MTOR ATM

2.21e-035251017C1257931
DiseaseAtrial Fibrillation

DNAH10 ABCC9 LRIG1 SYNE2

2.26e-031601014C0004238
DiseaseMammary Neoplasms

FOXM1 SYNE1 LDHB APOBEC3A NCOR1 MTOR ATM

2.26e-035271017C1458155
DiseaseBreast Carcinoma

FOXM1 SYNE1 LDHB APOBEC3A NCOR1 MTOR ATM

2.54e-035381017C0678222
DiseaseBronchiectasis

DNAI1 DNAH11

2.56e-03221012C0006267
Diseasepulmonary embolism

FABP2 DNAH17

3.31e-03251012EFO_0003827

Protein segments in the cluster

PeptideGeneStartEntry
KEVSWREFMKQHYLS

EDDM3B

26

P56851
SNMVVKVKWFYHPEE

BAHCC1

2546

Q9P281
DTWMKEFFLAHIYTE

CDC23

226

Q9UJX2
KFHWVEAFDDEMTEK

CAGE1

126

Q8TC20
SIMTYDEFKHCWDTF

APOBEC3A

151

P31941
TWKVDRSENYDKFME

FABP2

6

P12104
FEIMKSYGHTFEKHW

ARFGEF2

1356

Q9Y6D5
EMFYVDLDKKETVWH

HLA-DPA1

61

P20036
THTYLWVDDRAEFMK

DNAH11

1036

Q96DT5
DSSVKEDWKYVAMVI

CHRNA2

486

Q15822
TKDVELYEHWKTLMN

ABCC9

901

O60706
EVEQMHWSYQELKKT

CEP72

616

Q9P209
KIWDHTIKTPMFIYD

DNAI1

566

Q9UI46
FEHVKDWLEEAKMYV

RAB39A

101

Q14964
EYMKEDFLIKIETWH

PITPNA

101

Q00169
YSFEEEKWVEVASMK

IPP

506

Q9Y573
REWAKYMEVHEKASF

PTPN23

496

Q9H3S7
DMETKKDHPYTWRIE

PPME1

276

Q9Y570
ISRAVTKMVEEHFYW

FAXC

186

Q5TGI0
SAYHKEPWKAMEKAE

LRIG1

901

Q96JA1
AMYFEKEDVKVIFWS

LSG1

226

Q9H089
SIFRKVETDWHMVYL

NGLY1

526

Q96IV0
AEVWMDDFKSHVYMA

GALNT9

401

Q9HCQ5
WKEMEEKAIHYAEVG

CHUK

511

O15111
MSAISKHKIWFTIYD

FSIP2

4186

Q5CZC0
KEATSWMVKAETFHF

EID3

156

Q8N140
SVAYHLSKMGWKDIV

PDPR

56

Q8NCN5
KAEHILLWMSKDEIY

CUL7

61

Q14999
HASEVESAVWYVKKF

FBXO39

71

Q8N4B4
HKDVLKWGDEVEYML

GCLC

41

P48506
KTTFAWHTEDMDLYS

KDM4D

186

Q6B0I6
FSYNDSKEWEEAMAK

LMO7

1096

Q8WWI1
RHEIEMTEKEWKYYG

LAMA2

1301

P24043
YWVEMASLQVFEKMH

NLRP2

66

Q9NX02
DTWDYKSHVMTKFAE

NLRP5

231

P59047
TNFWKEDAMKTKTHY

MICB

166

Q29980
VSEMVFKASKITFHW

PTPRZ1

116

P23471
WMHVLEDIAKFFKAI

COMMD8

51

Q9NX08
KHTYTSWDLEDMEKY

ARHGAP32

1736

A7KAX9
WLKDVHMKGEYFVNV

ITGA2

1061

P17301
VYEDMDARKVVVTHW

DQX1

311

Q8TE96
EYMKDDFFIKIETWH

PITPNB

101

P48739
LATKTGHSFWEIYKM

ATM

1741

Q13315
VMVLSDHVIWKYKDA

DOCK10

1031

Q96BY6
IHYFDKGKMWEEAIA

DOCK1

1281

Q14185
MFSWKDHCEALYKEV

GIMAP2

81

Q9UG22
EVESKWSFMTELHEK

CCDC122

141

Q5T0U0
WSFMTELHEKRDFVK

CCDC122

146

Q5T0U0
FKVTIHEDSWKKAME

C16orf96

841

A6NNT2
MSKYLAHFLKEVTSW

DNAH17

1461

Q9UFH2
DYKRDVVEGSKQWHM

CDON

876

Q4KMG0
AEVWMDEFKSHVYMA

GALNT18

406

Q6P9A2
EEFMKTWRKYDTDHS

CALB1

101

P05937
KIIYSKGEEHDRWAM

CCDC66

351

A2RUB6
MREDYSDKVKASHWS

CDK11A

206

Q9UQ88
HCWKMDEVGITEYVK

MCF2

756

P10911
RMTLKDIYTWIEDHF

FOXM1

256

Q08050
SAKYSEAWQSKEEME

FSIP1

156

Q8NA03
ENWKEVHKMVVESAY

LDHB

226

P07195
YMVAAEHVWKDEQKE

GJB7

36

Q6PEY0
HKADISSWFMEAIEY

DUSP4

251

Q13115
SSWFMEAIEYIDAVK

DUSP4

256

Q13115
RHWKELMEKTSVFFE

DNAH10

1346

Q8IVF4
MFWKFDLNTTSHVDK

PPP6R2

1

O75170
WEDALVAYDKKMDTN

MTOR

1456

P42345
SSGFIDLLHDKWYKM

GRIN3B

796

O60391
SVSAADLEKYEKWMV

KATNAL1

471

Q9BW62
VTHFEWDMAKYPVKQ

ATP6V1C2

101

Q8NEY4
MYDSFWRQFKHSEKV

SESN1

451

Q9Y6P5
KEHEWMYTEALESLK

SMARCAD1

276

Q9H4L7
VIESMKYWREHAQKT

SPATA22

246

Q8NHS9
SMEVFSYHQGLKKWV

FARSA

416

Q9Y285
HEGDAYVVKWKFMVS

SVIL

1776

O95425
MKKWHEEVTAYRDEV

SYNE1

3641

Q8NF91
KMEEYSDLLKSTEAW

SYNE2

3786

Q8WXH0
HMKRWEYFIAAEEVI

F5

346

P12259
EHCFPDMTWDIKYKT

MRPL45

166

Q9BRJ2
YKDRQFMNVWTDHEK

NCOR1

431

O75376
FMNVWTDHEKEIFKD

NCOR1

436

O75376
EMYKDDWNKVSEHVG

SMARCC1

636

Q92922
VLEKLKEYSSMDAFW

SGPL1

126

O95470
KMKEESWHIHFFEYG

TBC1D9B

476

Q66K14
FADMEVLYWTHVKEQ

NCAPH2

386

Q6IBW4
DEEVNKWLHFYEMKA

C11orf54

231

Q9H0W9
HSKWYDAKEASMEGI

NCAM1

556

P13591
QTKWEHYKKEGSERM

WASHC5

436

Q12768
AWYSASKHNMADVKE

WDFY3

2831

Q8IZQ1
FWLMKAKDYPAHTEE

RMDN1

281

Q96DB5
HEMPKTFTFDAVYDW

KIF3B

51

O15066
WVPDRESYVSHMKKS

ZNF592

991

Q92610
MKYNDIAVTKSSWEE

USP25

621

Q9UHP3
KWENDKDVAMSFHYI

RAET1L

171

Q5VY80
EYTKMKTADHFWTDP

SGSM1

181

Q2NKQ1
VAMEEFEKALVWYES

TTC17

1096

Q96AE7
KWVTVAHEDYMELHF

THOC5

521

Q13769
FKTTESHMDWEKVAF

UBTF

46

P17480
KWENDKVVAMSFHYF

ULBP2

171

Q9BZM5
HAVEDYWFETKMSAL

ZNF485

81

Q8NCK3
EMRTYHWASFKDIHT

PTDSS1

241

P48651
MTHEDIVQESKKYWQ

ZC3H7B

651

Q9UGR2
WAHMKKYTEITATYF

AGL

506

P35573
DEETIFHALMMWVKY

KLHL1

371

Q9NR64
LKKHNDDFEMTSFWL

MYO5B

1536

Q9ULV0
ADKKSMEWFTVIEHY

MYBPC1

971

Q00872
DKKTMEWFTVLEHYR

MYBPC3

1106

Q14896
WSMHVAKIQSDREYK

NEB

2576

P20929
YTEAWDKDKTQIHIM

NEB

2966

P20929