Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	microtubule motor activity	KIF21B KIF23 KIF21A KIF7 KIF2A KIF5B KIF17	1.29e-07	70	112	7	GO:0003777
GeneOntologyMolecularFunction	cytoskeletal motor activity	KIF21B KIF23 MYO7A KIF21A KIF7 KIF2A KIF5B KIF17	3.34e-07	118	112	8	GO:0003774
GeneOntologyMolecularFunction	ribonucleoside triphosphate phosphatase activity	KIF21B KIF23 KIF21A CFTR RGS4 KIF7 RHOA RHOB RHOC GNA13 MOV10L1 KIF2A KIF5B KIF17 ATP2A3	2.82e-05	775	112	15	GO:0017111
GeneOntologyMolecularFunction	microtubule binding	KIF21B KIF23 KIF21A KIF7 CCDC88C KIF2A KIF5B KIF17 NIN	6.02e-05	308	112	9	GO:0008017
GeneOntologyMolecularFunction	pyrophosphatase activity	KIF21B KIF23 KIF21A CFTR RGS4 KIF7 RHOA RHOB RHOC GNA13 MOV10L1 KIF2A KIF5B KIF17 ATP2A3	6.96e-05	839	112	15	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	KIF21B KIF23 KIF21A CFTR RGS4 KIF7 RHOA RHOB RHOC GNA13 MOV10L1 KIF2A KIF5B KIF17 ATP2A3	7.05e-05	840	112	15	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	KIF21B KIF23 KIF21A CFTR RGS4 KIF7 RHOA RHOB RHOC GNA13 MOV10L1 KIF2A KIF5B KIF17 ATP2A3	7.05e-05	840	112	15	GO:0016818
GeneOntologyMolecularFunction	tubulin binding	KIF21B RANBP10 KIF23 KIF21A KIF7 CCDC88C KIF2A KIF5B KIF17 NIN	1.49e-04	428	112	10	GO:0015631
GeneOntologyMolecularFunction	ATP hydrolysis activity	KIF21B KIF23 KIF21A CFTR KIF7 MOV10L1 KIF2A KIF5B KIF17 ATP2A3	1.90e-04	441	112	10	GO:0016887
GeneOntologyMolecularFunction	guanyl-nucleotide exchange factor activity	RANBP10 KALRN CCDC88C ARHGEF33 GNA13 HERC2 DNMBP	3.28e-04	231	112	7	GO:0005085
GeneOntologyMolecularFunction	cytoskeletal protein binding	KIF21B RANBP10 KIF23 MYO7A KIF21A FMNL2 KIF7 SMTN FMNL3 RHOA CCDC88C KIF2A KIF5B CTNNA2 KIF17 NIN	4.14e-04	1099	112	16	GO:0008092
GeneOntologyMolecularFunction	CoA carboxylase activity	ACACA PCCB	4.61e-04	6	112	2	GO:0016421
GeneOntologyMolecularFunction	histone H3K9me2/H3K9me3 demethylase activity	KDM4D KDM1A	4.61e-04	6	112	2	GO:0140684
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	RANBP10 KALRN RGS4 CCDC88C ARHGEF33 GNA13 HERC2 DNMBP ACAP3 NCKAP1L	5.70e-04	507	112	10	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	RANBP10 KALRN RGS4 CCDC88C ARHGEF33 GNA13 HERC2 DNMBP ACAP3 NCKAP1L	5.70e-04	507	112	10	GO:0030695
GeneOntologyMolecularFunction	ligase activity, forming carbon-carbon bonds	ACACA PCCB	6.43e-04	7	112	2	GO:0016885
GeneOntologyMolecularFunction	chloride channel inhibitor activity	ANO9 CFTR	6.43e-04	7	112	2	GO:0019869
GeneOntologyMolecularFunction	ATP-dependent activity	KIF21B KIF23 MYO7A KIF21A CFTR KIF7 MOV10L1 KIF2A KIF5B KIF17 ATP2A3	6.72e-04	614	112	11	GO:0140657
GeneOntologyMolecularFunction	G-protein alpha-subunit binding	RGS4 CCDC88C IGF2R	1.80e-03	43	112	3	GO:0001965
GeneOntologyBiologicalProcess	cell morphogenesis	SPARC NCKAP1 KALRN MYO7A CFAP43 THOC2 FMNL2 FMNL3 RHOA CCDC88C CSF1R CELSR2 GNA13 IGHM PKHD1 ALCAM KIF5B CTNNA2 DNMBP KDM1A NCKAP1L NIN	2.00e-07	1194	108	22	GO:0000902
GeneOntologyBiologicalProcess	microtubule-based process	KIF21B RANBP10 KIF23 MCPH1 KIF21A E2F4 CFAP43 KIF7 RHOA CCDC88C GTF2B CELSR2 FBXW5 PKHD1 KIF2A KIF5B KIF17 UVRAG HYDIN NIN	5.28e-07	1058	108	20	GO:0007017
GeneOntologyBiologicalProcess	dendritic transport	KIF21B KIF2A KIF5B KIF17	2.59e-06	19	108	4	GO:0098935
GeneOntologyBiologicalProcess	modification of synaptic structure	KALRN RHOA RHOB KIF5B CTNNA2	6.95e-06	51	108	5	GO:0099563
GeneOntologyBiologicalProcess	regulation of modification of synaptic structure	KALRN RHOA RHOB KIF5B	1.53e-05	29	108	4	GO:1905244
GeneOntologyBiologicalProcess	microtubule cytoskeleton organization	RANBP10 KIF23 MCPH1 E2F4 CFAP43 RHOA CCDC88C GTF2B FBXW5 PKHD1 KIF2A UVRAG HYDIN NIN	2.37e-05	720	108	14	GO:0000226
GeneOntologyBiologicalProcess	skeletal muscle satellite cell migration	RHOA RHOC	2.72e-05	2	108	2	GO:1902766
GeneOntologyBiologicalProcess	microtubule-based movement	KIF21B KIF23 KIF21A CFAP43 KIF7 CCDC88C CELSR2 KIF2A KIF5B KIF17 HYDIN	5.57e-05	493	108	11	GO:0007018
GeneOntologyBiologicalProcess	modification of postsynaptic structure	KALRN RHOA RHOB CTNNA2	6.83e-05	42	108	4	GO:0099010
GeneOntologyBiologicalProcess	cortical actin cytoskeleton organization	NCKAP1 FMNL2 FMNL3 NCKAP1L	8.98e-05	45	108	4	GO:0030866
GeneOntologyBiologicalProcess	regulation of cell morphogenesis	SPARC KALRN FMNL2 FMNL3 CSF1R GNA13 IGHM DNMBP	1.91e-04	302	108	8	GO:0022604
GeneOntologyBiologicalProcess	regulation of modification of postsynaptic structure	KALRN RHOA RHOB	2.00e-04	22	108	3	GO:0099159
GeneOntologyBiologicalProcess	cortical cytoskeleton organization	NCKAP1 FMNL2 FMNL3 NCKAP1L	2.27e-04	57	108	4	GO:0030865
GeneOntologyCellularComponent	kinesin complex	KIF21B KIF23 KIF21A KIF7 KIF2A KIF5B KIF17	7.03e-09	49	111	7	GO:0005871
GeneOntologyCellularComponent	microtubule organizing center	KIF23 MCPH1 DCDC2B KMT2E SPPL2B SKI BBS9 KIF7 SMTN CCDC88C PKHD1 KIF2A KIF5B HERC2 KIF17 UVRAG NIN	6.89e-06	919	111	17	GO:0005815
GeneOntologyCellularComponent	microtubule associated complex	KIF21B KIF23 KIF21A KIF7 KIF2A KIF5B KIF17	2.45e-05	161	111	7	GO:0005875
Domain	Kinesin_motor_CS	KIF21B KIF23 KIF21A KIF7 KIF2A KIF5B KIF17	4.38e-09	41	112	7	IPR019821
Domain	Kinesin-like_fam	KIF21B KIF23 KIF21A KIF7 KIF2A KIF5B KIF17	6.22e-09	43	112	7	IPR027640
Domain	-	KIF21B KIF23 KIF21A KIF7 KIF2A KIF5B KIF17	7.36e-09	44	112	7	3.40.850.10
Domain	Kinesin	KIF21B KIF23 KIF21A KIF7 KIF2A KIF5B KIF17	7.36e-09	44	112	7	PF00225
Domain	KISc	KIF21B KIF23 KIF21A KIF7 KIF2A KIF5B KIF17	7.36e-09	44	112	7	SM00129
Domain	KINESIN_MOTOR_1	KIF21B KIF23 KIF21A KIF7 KIF2A KIF5B KIF17	7.36e-09	44	112	7	PS00411
Domain	Kinesin_motor_dom	KIF21B KIF23 KIF21A KIF7 KIF2A KIF5B KIF17	7.36e-09	44	112	7	IPR001752
Domain	KINESIN_MOTOR_2	KIF21B KIF23 KIF21A KIF7 KIF2A KIF5B KIF17	7.36e-09	44	112	7	PS50067
Domain	Nck-associated_protein-1	NCKAP1 NCKAP1L	3.56e-05	2	112	2	IPR019137
Domain	Nckap1	NCKAP1 NCKAP1L	3.56e-05	2	112	2	PF09735
Domain	P-loop_NTPase	KIF21B KIF23 MYO7A KIF21A CFTR KIF7 RHOA RHOB RHOC LRRIQ1 GNA13 MOV10L1 KIF2A KIF5B KIF17 HYDIN	4.53e-05	848	112	16	IPR027417
Domain	TECPR	TECPR2 HERC2	1.07e-04	3	112	2	SM00706
Domain	Beta-propeller_rpt_TECPR	TECPR2 HERC2	1.07e-04	3	112	2	IPR006624
Domain	Carboxyl_trans	ACACA PCCB	2.12e-04	4	112	2	PF01039
Domain	COA_CT_CTER	ACACA PCCB	2.12e-04	4	112	2	PS50989
Domain	COA_CT_NTER	ACACA PCCB	2.12e-04	4	112	2	PS50980
Domain	COA_CT_N	ACACA PCCB	2.12e-04	4	112	2	IPR011762
Domain	COA_CT_C	ACACA PCCB	2.12e-04	4	112	2	IPR011763
Domain	Carboxyl_trans	ACACA PCCB	2.12e-04	4	112	2	IPR000022
Domain	RHO	RHOA RHOB RHOC	2.22e-04	20	112	3	PS51420
Domain	Drf_GBD	FMNL2 FMNL3	1.25e-03	9	112	2	PF06371
Domain	Drf_FH3	FMNL2 FMNL3	1.25e-03	9	112	2	PF06367
Domain	FH3_dom	FMNL2 FMNL3	1.25e-03	9	112	2	IPR010472
Domain	GTPase-bd	FMNL2 FMNL3	1.25e-03	9	112	2	IPR010473
Domain	Drf_FH3	FMNL2 FMNL3	1.25e-03	9	112	2	SM01139
Domain	Drf_GBD	FMNL2 FMNL3	1.25e-03	9	112	2	SM01140
Domain	WD40_repeat	KIF21B MED16 KIF21A CFAP43 TECPR2 FBXW5 HERC2	1.27e-03	272	112	7	IPR001680
Domain	WD_REPEATS_1	KIF21B MED16 KIF21A CFAP43 TECPR2 FBXW5 HERC2	1.44e-03	278	112	7	PS00678
Domain	WD_REPEATS_2	KIF21B MED16 KIF21A CFAP43 TECPR2 FBXW5 HERC2	1.47e-03	279	112	7	PS50082
Domain	WD_REPEATS_REGION	KIF21B MED16 KIF21A CFAP43 TECPR2 FBXW5 HERC2	1.47e-03	279	112	7	PS50294
Domain	GBD/FH3_dom	FMNL2 FMNL3	1.89e-03	11	112	2	IPR014768
Domain	GBD_FH3	FMNL2 FMNL3	1.89e-03	11	112	2	PS51232
Domain	Quinoprot_gluc/sorb_DH	MED16 FBXW5	2.26e-03	12	112	2	IPR011041
Domain	-	PGGT1B C3	2.26e-03	12	112	2	1.50.10.20
Domain	EF_HAND_2	CIB2 SPARC SLC25A12 GUCA1A PLCH1 NIN	2.70e-03	231	112	6	PS50222
Domain	EF_hand_dom	CIB2 SPARC SLC25A12 GUCA1A PLCH1 NIN	2.76e-03	232	112	6	IPR002048
Domain	FH2	FMNL2 FMNL3	3.56e-03	15	112	2	PS51444
Domain	FH2_Formin	FMNL2 FMNL3	3.56e-03	15	112	2	IPR015425
Domain	FH2	FMNL2 FMNL3	3.56e-03	15	112	2	PF02181
Domain	FH2	FMNL2 FMNL3	3.56e-03	15	112	2	SM00498
Domain	EF_Hand_1_Ca_BS	CIB2 SPARC SLC25A12 GUCA1A PLCH1	4.08e-03	175	112	5	IPR018247
Domain	-	CIB2 SPARC SLC25A12 GUCA1A PLCH1 NIN	4.90e-03	261	112	6	1.10.238.10
Domain	Ig/MHC_CS	HLA-G IGHM ALCAM	5.10e-03	58	112	3	IPR003006
Domain	Terpenoid_cyclase/PrenylTrfase	PGGT1B C3	5.12e-03	18	112	2	IPR008930
Domain	WD40	KIF21B MED16 KIF21A CFAP43 TECPR2 FBXW5	5.56e-03	268	112	6	SM00320
Pathway	REACTOME_RHO_GTPASE_EFFECTORS	NCKAP1 CFTR FMNL2 FMNL3 CENPP RHOA RHOB RHOC KIF2A KIF5B NCKAP1L	6.97e-07	257	90	11	MM14755
Pathway	REACTOME_RHO_GTPASE_EFFECTORS	NCKAP1 CFTR FMNL2 FMNL3 CENPP RHOA RHOB RHOC KIF2A KIF5B KDM1A NCKAP1L	9.44e-07	323	90	12	M27080
Pathway	REACTOME_RHO_GTPASES_ACTIVATE_ROCKS	RHOA RHOB RHOC	2.49e-06	5	90	3	MM15221
Pathway	REACTOME_RHO_GTPASES_ACTIVATE_CIT	RHOA RHOB RHOC	8.65e-06	7	90	3	MM15217
Pathway	REACTOME_G_ALPHA_12_13_SIGNALLING_EVENTS	KALRN RHOA RHOB RHOC ARHGEF33 GNA13	9.43e-06	77	90	6	MM15044
Pathway	REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3	NCKAP1 KALRN CFTR FMNL2 FMNL3 CENPP RHOA RHOB RHOC GFOD1 GNA13 KIF2A KIF5B DNMBP KDM1A NCKAP1L	1.13e-05	720	90	16	M41838
Pathway	REACTOME_G_ALPHA_12_13_SIGNALLING_EVENTS	KALRN RHOA RHOB RHOC ARHGEF33 GNA13	1.18e-05	80	90	6	M800
Pathway	REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3	NCKAP1 KALRN CFTR FMNL2 FMNL3 CENPP RHOA RHOB RHOC GFOD1 GNA13 KIF2A KIF5B DNMBP NCKAP1L	1.39e-05	649	90	15	MM15690
Pathway	REACTOME_RHO_GTPASES_ACTIVATE_RHOTEKIN_AND_RHOPHILINS	RHOA RHOB RHOC	2.06e-05	9	90	3	M27551
Pathway	REACTOME_RHO_GTPASE_CYCLE	NCKAP1 KALRN CFTR FMNL2 FMNL3 RHOA RHOB RHOC GFOD1 GNA13 DNMBP NCKAP1L	2.17e-05	439	90	12	MM15595
Pathway	REACTOME_RHO_GTPASE_CYCLE	NCKAP1 KALRN CFTR FMNL2 FMNL3 RHOA RHOB RHOC GFOD1 GNA13 DNMBP NCKAP1L	2.77e-05	450	90	12	M27078
Pathway	REACTOME_KINESINS	KIF21B KIF23 KIF21A KIF2A KIF5B	3.06e-05	57	90	5	MM15714
Pathway	REACTOME_RHO_GTPASES_ACTIVATE_FORMINS	FMNL2 FMNL3 CENPP RHOA RHOB RHOC KIF2A	3.08e-05	140	90	7	M27550
Pathway	REACTOME_RHO_GTPASES_ACTIVATE_FORMINS	FMNL2 FMNL3 CENPP RHOA RHOB RHOC KIF2A	3.23e-05	141	90	7	MM15266
Pathway	REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE	RHOA RHOB RHOC	4.00e-05	11	90	3	MM15046
Pathway	REACTOME_KINESINS	KIF21B KIF23 KIF21A KIF2A KIF5B	4.26e-05	61	90	5	M977
Pathway	REACTOME_HEMOSTASIS	KIF21B KIF23 SPARC VWF KIF21A ECM1 RHOA RHOB GNA13 KIF2A KIF5B ATP2A3 KDM1A	6.46e-05	571	90	13	MM14472
Pathway	REACTOME_HEMOSTASIS	KIF21B KIF23 SPARC VWF KIF21A ECM1 RHOA RHOB GNA13 IGHM KIF2A KIF5B ATP2A3 KDM1A	9.57e-05	679	90	14	M8395
Pathway	REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION	KIF21B KIF23 KIF21A KIF2A KIF5B KDM1A	9.67e-05	116	90	6	MM15715
Pathway	REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING	RHOA RHOB RHOC	1.08e-04	15	90	3	MM15037
Pathway	REACTOME_RHO_GTPASES_ACTIVATE_ROCKS	RHOA RHOB RHOC	2.26e-04	19	90	3	M27493
Pathway	REACTOME_RHO_GTPASES_ACTIVATE_CIT	RHOA RHOB RHOC	2.26e-04	19	90	3	M27489
Pathway	REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE	RHOA RHOB RHOC	2.65e-04	20	90	3	M18415
Pathway	REACTOME_DEATH_RECEPTOR_SIGNALING	KALRN SPPL2B RHOA ARHGEF33 GNA13 USP4	2.92e-04	142	90	6	MM15431
Pathway	REACTOME_COPI_DEPENDENT_GOLGI_TO_ER_RETROGRADE_TRAFFIC	KIF21B KIF23 KIF21A KIF2A KIF5B	4.04e-04	98	90	5	MM15352
Pathway	REACTOME_RHO_GTPASES_ACTIVATE_PKNS	RHOA RHOB RHOC	4.06e-04	23	90	3	MM15216
Pathway	REACTOME_COPI_DEPENDENT_GOLGI_TO_ER_RETROGRADE_TRAFFIC	KIF21B KIF23 KIF21A KIF2A KIF5B	4.43e-04	100	90	5	M27650
Pathway	REACTOME_DEATH_RECEPTOR_SIGNALING	KALRN SPPL2B RHOA ARHGEF33 GNA13 USP4	4.51e-04	154	90	6	M27697
Pathway	REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING	RHOA RHOB RHOC	4.62e-04	24	90	3	M2243
Pathway	REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION	KIF21B KIF23 KIF21A KIF2A KIF5B KDM1A	7.60e-04	170	90	6	M941
Pathway	REACTOME_RHOC_GTPASE_CYCLE	FMNL2 FMNL3 RHOA RHOC	1.03e-03	70	90	4	MM15597
Pathway	REACTOME_DEFECTS_IN_BIOTIN_BTN_METABOLISM	ACACA PCCB	1.10e-03	8	90	2	M27248
Pathway	REACTOME_RHOC_GTPASE_CYCLE	FMNL2 FMNL3 RHOA RHOC	1.27e-03	74	90	4	M41807
Pathway	REACTOME_INTRA_GOLGI_AND_RETROGRADE_GOLGI_TO_ER_TRAFFIC	KIF21B KIF23 KIF21A IGF2R KIF2A KIF5B	1.31e-03	189	90	6	MM15356
Pubmed	All kinesin superfamily protein, KIF, genes in mouse and human.	KIF21B KIF23 KIF21A KIF7 KIF2A KIF17	2.20e-09	37	113	6	11416179
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	KIF21B RANBP10 KIF23 NCKAP1 KALRN KIF21A TMEM132B KIF7 RHOC CCDC88C IGF2R CELSR2 KIF2A KIF5B CTNNA2 HERC2 KDM1A	1.51e-08	963	113	17	28671696
Pubmed	RhoA, RhoB and RhoC have different roles in cancer cell migration.	RHOA RHOB RHOC	3.34e-08	3	113	3	23488932
Pubmed	A novel strategy for specifically down-regulating individual Rho GTPase activity in tumor cells.	RHOA RHOB RHOC	3.34e-08	3	113	3	12939257
Pubmed	Transcriptional and post-transcriptional regulation of the genes encoding the small GTPases RhoA, RhoB, and RhoC: implications for the pathogenesis of human diseases.	RHOA RHOB RHOC	3.34e-08	3	113	3	29500478
Pubmed	RhoA, RhoB and RhoC differentially regulate endothelial barrier function.	RHOA RHOB RHOC	3.34e-08	3	113	3	28949796
Pubmed	Rho isoforms have distinct and specific functions in the process of epithelial to mesenchymal transition in renal proximal tubular cells.	RHOA RHOB RHOC	3.34e-08	3	113	3	19477269
Pubmed	Divergence of Rho residue 43 impacts GEF activity.	RHOA RHOB RHOC	3.34e-08	3	113	3	22673745
Pubmed	The Role of RhoA, RhoB and RhoC GTPases in Cell Morphology, Proliferation and Migration in Human Cytomegalovirus (HCMV) Infected Glioblastoma Cells.	RHOA RHOB RHOC	3.34e-08	3	113	3	26741994
Pubmed	Prenylation inhibitors stimulate both estrogen receptor alpha transcriptional activity through AF-1 and AF-2 and estrogen receptor beta transcriptional activity.	RHOA RHOB RHOC	3.34e-08	3	113	3	15642170
Pubmed	Spatiotemporal analysis of RhoA/B/C activation in primary human endothelial cells.	RHOA RHOB RHOC	3.34e-08	3	113	3	27147504
Pubmed	Cooperation between mDia1 and ROCK in Rho-induced actin reorganization.	RHOA RHOB RHOC	1.33e-07	4	113	3	10559899
Pubmed	XPLN, a guanine nucleotide exchange factor for RhoA and RhoB, but not RhoC.	RHOA RHOB RHOC	1.33e-07	4	113	3	12221096
Pubmed	Rhotekin, a new putative target for Rho bearing homology to a serine/threonine kinase, PKN, and rhophilin in the rho-binding domain.	RHOA RHOB RHOC	1.33e-07	4	113	3	8662891
Pubmed	Rho isoform-specific interaction with IQGAP1 promotes breast cancer cell proliferation and migration.	RHOA RHOB RHOC	1.33e-07	4	113	3	22992742
Pubmed	The small GTP-binding protein Rho binds to and activates a 160 kDa Ser/Thr protein kinase homologous to myotonic dystrophy kinase.	RHOA RHOB RHOC	3.32e-07	5	113	3	8617235
Pubmed	Rho localization in cells and tissues.	RHOA RHOB RHOC	3.32e-07	5	113	3	15093731
Pubmed	A novel partner for the GTP-bound forms of rho and rac.	RHOA RHOB RHOC	3.32e-07	5	113	3	8543060
Pubmed	Small GTP-binding proteins and the regulation of the actin cytoskeleton.	RHOA RHOB RHOC	6.63e-07	6	113	3	7888179
Pubmed	Rho GTPases and the actin cytoskeleton.	RHOA RHOB RHOC	6.63e-07	6	113	3	9438836
Pubmed	Dissecting the role of Rho-mediated signaling in contractile ring formation.	KIF23 RHOB RHOC	6.63e-07	6	113	3	16236794
Pubmed	The bacterial virulence factor lymphostatin compromises intestinal epithelial barrier function by modulating rho GTPases.	RHOA RHOB RHOC	6.63e-07	6	113	3	19286565
Pubmed	RHO binding to FAM65A regulates Golgi reorientation during cell migration.	RHOA RHOB RHOC	1.16e-06	7	113	3	27807006
Pubmed	Identification and classification of 16 new kinesin superfamily (KIF) proteins in mouse genome.	KIF7 KIF2A KIF5B KIF17	1.27e-06	25	113	4	9275178
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	KIF23 MED16 THOC2 KIF7 RHOA GTF2B IPO9 C3 KIF5B KDM1A RPAP2 NIN	1.34e-06	645	113	12	25281560
Pubmed	Molecular genetics of adult ADHD: converging evidence from genome-wide association and extended pedigree linkage studies.	KALRN CFAP43 GPC6 CTNNA2	2.04e-06	28	113	4	18839057
Pubmed	Distinct roles of Rac1/Cdc42 and Rho/Rock for axon outgrowth and nucleokinesis of precerebellar neurons toward netrin 1.	RHOA RHOB RHOC	2.77e-06	9	113	3	15151987
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	RANBP10 ACACA KALRN MYO7A CFAP43 SPPL2B REXO1 CPTP CCDC88C IGF2R CELSR2 HERC2 DNMBP ATP2A3 UVRAG	3.05e-06	1105	113	15	35748872
Pubmed	Network organization of the huntingtin proteomic interactome in mammalian brain.	KIF21B SYT12 NCKAP1 KIF21A BLZF1 RGS4 SLC25A12 GNA13 KIF2A KIF5B ATP2A3	6.04e-06	621	113	11	22794259
Pubmed	Kctd13 deletion reduces synaptic transmission via increased RhoA.	RHOA RHOB RHOC	9.33e-06	13	113	3	29088697
Pubmed	A high expression ratio of RhoA/RhoB is associated with the migratory and invasive properties of basal-like Breast Tumors.	RHOA RHOB	1.05e-05	2	113	2	33162807
Pubmed	RhoA GTPase is dispensable for actomyosin regulation but is essential for mitosis in primary mouse embryonic fibroblasts.	RHOA RHOC	1.05e-05	2	113	2	21454503
Pubmed	Activation of a bacterial virulence protein by the GTPase RhoA.	RHOA RHOC	1.05e-05	2	113	2	19887681
Pubmed	Novel dendritic kinesin sorting identified by different process targeting of two related kinesins: KIF21A and KIF21B.	KIF21B KIF21A	1.05e-05	2	113	2	10225949
Pubmed	Coding sequence of human rho cDNAs clone 6 and clone 9.	RHOB RHOC	1.05e-05	2	113	2	3283705
Pubmed	Functional analysis of the promoters of the small GTPases RhoA and RhoB in embryonic stem cells.	RHOA RHOB	1.05e-05	2	113	2	28739254
Pubmed	Up-regulation of small GTPases, RhoA and RhoC, is associated with tumor progression in ovarian carcinoma.	RHOA RHOC	1.05e-05	2	113	2	12808121
Pubmed	Kinesin-1 plays multiple roles during the vaccinia virus life cycle.	KIF2A KIF5B	1.05e-05	2	113	2	17394562
Pubmed	Therapeutic Potential for CFTR Correctors in Autosomal Recessive Polycystic Kidney Disease.	CFTR PKHD1	1.05e-05	2	113	2	34329764
Pubmed	Endothelial RhoB and RhoC are dispensable for leukocyte diapedesis and for maintaining vascular integrity during diapedesis.	RHOB RHOC	1.05e-05	2	113	2	28960175
Pubmed	A strategy to identify protein-N-myristoylation-dependent phosphorylation reactions of cellular proteins by using Phos-tag SDS-PAGE.	FMNL2 FMNL3	1.05e-05	2	113	2	31751425
Pubmed	Characterization of the roles of RHOC and RHOA GTPases in invasion, motility, and matrix adhesion in inflammatory and aggressive breast cancers.	RHOA RHOC	1.05e-05	2	113	2	20503409
Pubmed	Guanine nucleotide exchange regulates membrane translocation of Rac/Rho GTP-binding proteins.	RHOA RHOC	1.05e-05	2	113	2	7989340
Pubmed	Inactivating mutations in GNA13 and RHOA in Burkitt's lymphoma and diffuse large B-cell lymphoma: a tumor suppressor function for the Gα13/RhoA axis in B cells.	RHOA GNA13	1.05e-05	2	113	2	26616858
Pubmed	Nanobody-Based Quantification of GTP-Bound RHO Conformation Reveals RHOA and RHOC Activation Independent from Their Total Expression in Breast Cancer.	RHOA RHOC	1.05e-05	2	113	2	33825439
Pubmed	Silencing of RhoA and RhoC expression by RNA interference suppresses human colorectal carcinoma growth in vivo.	RHOA RHOC	1.05e-05	2	113	2	20828398
Pubmed	Anti-RhoA and anti-RhoC siRNAs inhibit the proliferation and invasiveness of MDA-MB-231 breast cancer cells in vitro and in vivo.	RHOA RHOC	1.05e-05	2	113	2	15668138
Pubmed	Clinical and prognostic significance of RhoA and RhoC gene expression in esophageal squamous cell carcinoma.	RHOA RHOC	1.05e-05	2	113	2	17896152
Pubmed	The HEM proteins: a novel family of tissue-specific transmembrane proteins expressed from invertebrates through mammals with an essential function in oogenesis.	NCKAP1 NCKAP1L	1.05e-05	2	113	2	7643388
Pubmed	Sequence of rho small GTP-binding protein cDNAs from human retina and identification of novel 5' end cloning artifacts.	RHOA RHOC	1.05e-05	2	113	2	7835413
Pubmed	A novel ras-related gene family.	RHOB RHOC	1.05e-05	2	113	2	3888408
Pubmed	Loss of RhoA promotes skin tumor formation and invasion by upregulation of RhoB.	RHOA RHOB	1.05e-05	2	113	2	29059167
Pubmed	Chromosome localization of human ARH genes, a ras-related gene family.	RHOA RHOB	1.05e-05	2	113	2	2407642
Pubmed	The GNA13-RhoA signaling axis suppresses expression of tumor protective Kallikreins.	RHOA GNA13	1.05e-05	2	113	2	27424208
Pubmed	FMNL formins boost lamellipodial force generation.	FMNL2 FMNL3	1.05e-05	2	113	2	28327544
Pubmed	GTPases Rho distribution in intraepithelial and invasive neoplasias of the uterine cervix.	RHOA RHOB	1.05e-05	2	113	2	24984542
Pubmed	ABCs of RhoGTPases indicating potential role as oncotargets.	RHOA RHOC	1.05e-05	2	113	2	28508825
Pubmed	Immunolocalization of RhoA and RhoB GTPases in pleomorphic adenoma of the parotid.	RHOA RHOB	1.05e-05	2	113	2	25454559
Pubmed	Expression of RhoA and RhoC in colorectal carcinoma and its relations with clinicopathological parameters.	RHOA RHOC	1.05e-05	2	113	2	19499974
Pubmed	Formin-like 2 drives amoeboid invasive cell motility downstream of RhoC.	FMNL2 RHOC	1.05e-05	2	113	2	20101212
Pubmed	Protein N-myristoylation is required for cellular morphological changes induced by two formin family proteins, FMNL2 and FMNL3.	FMNL2 FMNL3	1.05e-05	2	113	2	22790947
Pubmed	IgM antibodies to apoptosis-associated determinants recruit C1q and enhance dendritic cell phagocytosis of apoptotic cells.	IGHM C3	1.05e-05	2	113	2	19414754
Pubmed	Acetyl-CoA carboxylase inhibition regulates microtubule dynamics and intracellular transport in cystic fibrosis epithelial cells.	ACACA CFTR	1.05e-05	2	113	2	30892081
Pubmed	Megakaryocyte-specific RhoA deficiency causes macrothrombocytopenia and defective platelet activation in hemostasis and thrombosis.	RHOA GNA13	1.05e-05	2	113	2	22045984
Pubmed	Ovarian clear cell carcinomas: RHO GTPases may contribute to explain their singular biologic behavior.	RHOA RHOC	1.05e-05	2	113	2	21208644
Pubmed	Specific induction of migration and invasion of pancreatic carcinoma cells by RhoC, which differs from RhoA in its localisation and activity.	RHOA RHOC	1.05e-05	2	113	2	19642867
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	ACACA NCKAP1 ACOT9 OSGEP KIF7 CCDC88C IGF2R KIF5B HERC2 DNMBP PCCB NIN	2.25e-05	853	113	12	28718761
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	ACACA MCPH1 MYO7A KIF21A HLA-G FMNL2 TMEM132B RHOA KDM4D ARHGEF33 PKHD1	2.91e-05	736	113	11	29676528
Pubmed	Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray.	NCKAP1 HLA-G RHOA IGF2R SLC25A12 KCNJ2 HERC2 DNMBP	3.01e-05	371	113	8	15747579
Pubmed	Post-translational modifications of p21rho proteins.	PGGT1B RHOB	3.13e-05	3	113	2	1400319
Pubmed	Complement serves as a switch between CD4+ T cell-independent and -dependent RBC antibody responses.	IGHM C3	3.13e-05	3	113	2	30429364
Pubmed	Activated G(alpha)13 impairs cell invasiveness through p190RhoGAP-mediated inhibition of RhoA activity.	RHOA GNA13	3.13e-05	3	113	2	18922893
Pubmed	Antigen modulation as a potential mechanism of anti-KEL immunoprophylaxis in mice.	IGHM C3	3.13e-05	3	113	2	27688803
Pubmed	RhoA-GDP regulates RhoB protein stability. Potential involvement of RhoGDIalpha.	RHOA RHOB	3.13e-05	3	113	2	18524772
Pubmed	Targeted disruption of protein kinase C epsilon reduces cell invasion and motility through inactivation of RhoA and RhoC GTPases in head and neck squamous cell carcinoma.	RHOA RHOC	3.13e-05	3	113	2	17018591
Pubmed	RhoA and RhoC differentially modulate estrogen receptor α recruitment, transcriptional activities, and expression in breast cancer cells (MCF-7).	RHOA RHOC	3.13e-05	3	113	2	24096540
Pubmed	ACACA reduces lipid accumulation through dual regulation of lipid metabolism and mitochondrial function via AMPK- PPARα- CPT1A axis.	ACACA CPT1A	3.13e-05	3	113	2	38395901
Pubmed	Structural and mechanistic insights into the interaction between Rho and mammalian Dia.	RHOA RHOC	3.13e-05	3	113	2	15864301
Pubmed	Usher proteins in inner ear structure and function.	CIB2 MYO7A	3.13e-05	3	113	2	24022220
Pubmed	Rho/ROCK/actin signaling regulates membrane androgen receptor induced apoptosis in prostate cancer cells.	RHOA RHOB	3.13e-05	3	113	2	18694745
Pubmed	Prospective isolation and molecular characterization of hematopoietic stem cells with durable self-renewal potential.	VWF RHOB	3.13e-05	3	113	2	19377048
Pubmed	Insulin-like growth factor 2 receptor is an IFNgamma-inducible microglial protein that facilitates intracellular HIV replication: implications for HIV-induced neurocognitive disorders.	IGF2R CSF1R	3.13e-05	3	113	2	20889566
Pubmed	A p27(kip1)-binding protein, p27RF-Rho, promotes cancer metastasis via activation of RhoA and RhoC.	RHOA RHOC	3.13e-05	3	113	2	21087931
Pubmed	RhoA and RhoC are both required for the ROCK II-dependent promotion of centrosome duplication.	RHOA RHOC	3.13e-05	3	113	2	20697357
Pubmed	Syndecan-2 regulation of morphology in breast carcinoma cells is dependent on RhoGTPases.	RHOA RHOC	3.13e-05	3	113	2	24447566
Pubmed	Consequences of mevalonate depletion. Differential transcriptional, translational, and post-translational up-regulation of Ras, Rap1a, RhoA, AND RhoB.	RHOA RHOB	3.13e-05	3	113	2	11788600
Pubmed	RhoB, not RhoA, represses the transcription of the transforming growth factor beta type II receptor by a mechanism involving activator protein 1.	RHOA RHOB	3.13e-05	3	113	2	11741970
Pubmed	SWAP-70 regulates RhoA/RhoB-dependent MHCII surface localization in dendritic cells.	RHOA RHOB	3.13e-05	3	113	2	18802007
Pubmed	RhoGDIα-dependent balance between RhoA and RhoC is a key regulator of cancer cell tumorigenesis.	RHOA RHOC	3.13e-05	3	113	2	21757538
Pubmed	Selective expression of the small GTPase RhoB in the early developing mouse lens.	RHOA RHOB	3.13e-05	3	113	2	11747086
Pubmed	Inhibition of B cell-dependent lymphoid follicle formation prevents lymphocytic bronchiolitis after lung transplantation.	MCPH1 IGHM	3.13e-05	3	113	2	30728330
Pubmed	Alterations of the CIB2 calcium- and integrin-binding protein cause Usher syndrome type 1J and nonsyndromic deafness DFNB48.	CIB2 MYO7A	3.13e-05	3	113	2	23023331
Pubmed	RhoA and RhoC are involved in stromal cell-derived factor-1-induced cell migration by regulating F-actin redistribution and assembly.	RHOA RHOC	3.13e-05	3	113	2	28536953
Pubmed	CSN5 inhibition triggers inflammatory signaling and Rho/ROCK-dependent loss of endothelial integrity.	RHOA RHOB	3.13e-05	3	113	2	31148579
Pubmed	The clearance mechanism of chilled blood platelets.	VWF C3	3.13e-05	3	113	2	12526796
Pubmed	RhoA determines disease progression by controlling neutrophil motility and restricting hyperresponsiveness.	RHOA RHOB	3.13e-05	3	113	2	24782506
Pubmed	Complement in breast milk modifies offspring gut microbiota to promote infant health.	IGHM C3	3.13e-05	3	113	2	38242132
Pubmed	Identification and characterization of human FMNL1, FMNL2 and FMNL3 genes in silico.	FMNL2 FMNL3	3.13e-05	3	113	2	12684686
Pubmed	Myosin-interacting guanine exchange factor (MyoGEF) regulates the invasion activity of MDA-MB-231 breast cancer cells through activation of RhoA and RhoC.	RHOA RHOC	3.13e-05	3	113	2	19421144
Pubmed	Skin injuries reduce survival and modulate corticosterone, C-reactive protein, complement component 3, IgM, and prostaglandin E 2 after whole-body reactor-produced mixed field (n + γ-photons) irradiation.	IGHM C3	3.13e-05	3	113	2	24175013
Interaction	SBF1 interactions	B4GALT2 CIB2 PTGES3L RHOA RHOB RHOC GFOD1 FBXW5 KLHL14	2.33e-07	157	112	9	int:SBF1
Interaction	CTNNA1 interactions	MYO7A CFTR E2F4 FMNL2 RHOA RHOB RHOC CCDC88C IPO9 CTNNA2 HERC2 PLCH1	5.31e-07	347	112	12	int:CTNNA1
Interaction	DAAM1 interactions	CFTR FMNL2 FMNL3 RHOA RHOB RHOC	2.98e-06	72	112	6	int:DAAM1
Interaction	DIAPH3 interactions	FMNL2 FMNL3 RHOA RHOB RHOC KDM1A NIN	6.30e-06	125	112	7	int:DIAPH3
Interaction	DIAPH1 interactions	CFTR SKI FMNL2 FMNL3 RHOA RHOB RHOC KIF5B	6.34e-06	176	112	8	int:DIAPH1
Interaction	SLK interactions	MYO7A RHOA RHOB RHOC IPO9 USP4 KIF2A KIF5B	8.44e-06	183	112	8	int:SLK
Interaction	BICD1 interactions	ACACA NCKAP1 KIF7 CCDC88C C3 HERC2 DNMBP PCCB NIN	1.09e-05	250	112	9	int:BICD1
Interaction	FZD6 interactions	HLA-G RHOA RHOB RHOC CCDC88C	1.35e-05	55	112	5	int:FZD6
Interaction	IQGAP3 interactions	B4GALT2 KIF23 CFTR RHOA RHOB RHOC KLHL14	1.39e-05	141	112	7	int:IQGAP3
Interaction	PHLDB2 interactions	KIF23 CFTR E2F4 KIF7 RHOA RHOB RHOC	1.52e-05	143	112	7	int:PHLDB2
Interaction	SLC38A5 interactions	SPPL2B RHOA RHOB ATP2A3	2.53e-05	31	112	4	int:SLC38A5
Interaction	PKP4 interactions	KALRN OSGEP RHOA RHOB RHOC CCDC88C NIN	3.02e-05	159	112	7	int:PKP4
Interaction	TENM2 interactions	RHOA RHOB RHOC	3.54e-05	12	112	3	int:TENM2
Interaction	IFT122 interactions	B4GALT2 CIB2 GFOD1 FBXW5 KLHL14	3.56e-05	67	112	5	int:IFT122
Interaction	GPRC5A interactions	KIF23 CFTR RHOA RHOB RHOC	3.82e-05	68	112	5	int:GPRC5A
Interaction	MED4 interactions	KIF21B MED16 POLR2G THOC2 KIF7 GTF2B C3 KIF5B HERC2 RPAP2 NIN	4.22e-05	450	112	11	int:MED4
Interaction	TANGO6 interactions	B4GALT2 CIB2 FBXW5 KLHL14 KDM1A	4.71e-05	71	112	5	int:TANGO6
Interaction	GNA11 interactions	KIF23 CFTR RHOA RHOB RHOC GNA13	4.88e-05	117	112	6	int:GNA11
Interaction	FAT4 interactions	B4GALT2 DCDC2B RHOA RHOB RHOC	5.04e-05	72	112	5	int:FAT4
Interaction	MUC13 interactions	CFTR RHOA RHOB RHOC	5.18e-05	37	112	4	int:MUC13
Interaction	SLC11A2 interactions	SPPL2B RHOA RHOB RHOC	5.77e-05	38	112	4	int:SLC11A2
Interaction	POLR2G interactions	MCPH1 MED16 POLR2G PSMB9 GTF2B KIF5B RPAP2	6.41e-05	179	112	7	int:POLR2G
Interaction	HTT interactions	KIF21B KIF23 SYT12 NCKAP1 KIF21A BLZF1 RGS4 RHOA RHOC IPO9 SLC25A12 GNA13 KIF2A KIF5B ATP2A3 KDM1A	7.02e-05	949	112	16	int:HTT
Interaction	NECTIN3 interactions	SPPL2B FMNL2 RHOA RHOB RHOC	7.41e-05	78	112	5	int:NECTIN3
Interaction	CCN1 interactions	CFTR RHOA RHOB RHOC	8.60e-05	42	112	4	int:CCN1
Interaction	DBNL interactions	CFTR OSGEP FMNL2 USP4 HERC2 KLHL14 PLCH1	9.33e-05	190	112	7	int:DBNL
Interaction	KRIT1 interactions	RGS4 RHOA RHOB RHOC	1.03e-04	44	112	4	int:KRIT1
Interaction	PCCA interactions	ACACA SLC25A12 FBXW5 USP4 PCCB KDM1A	1.04e-04	134	112	6	int:PCCA
Interaction	MED30 interactions	MED16 POLR2G E2F4 HERC2 RPAP2	1.05e-04	84	112	5	int:MED30
Interaction	RHOA interactions	NCKAP1 ACOT9 CFTR OSGEP CPT1A CLOCK FMNL2 FMNL3 RHOA RHOB RHOC CCDC88C IPO9 IGF2R SLC25A12 GNA13 CTNNA2 PLCH1	1.06e-04	1199	112	18	int:RHOA
Interaction	SAMD3 interactions	CFTR HERC2 KDM1A	1.07e-04	17	112	3	int:SAMD3
Interaction	GNAS interactions	KIF23 CFTR THOC2 RHOA RHOB RHOC SLC25A12 HERC2	1.15e-04	264	112	8	int:GNAS
Interaction	PARD3B interactions	CIB2 RHOA RHOB RHOC	1.23e-04	46	112	4	int:PARD3B
Interaction	ITGA1 interactions	RHOA RHOB RHOC ALCAM	1.23e-04	46	112	4	int:ITGA1
Interaction	SLCO4A1 interactions	ACACA RHOA RHOB RHOC	1.23e-04	46	112	4	int:SLCO4A1
Interaction	SLC16A1 interactions	CFTR RHOA RHOB RHOC GNA13 HERC2 KDM1A	1.28e-04	200	112	7	int:SLC16A1
Interaction	ACSL4 interactions	KIF23 CFTR RHOA RHOB IGHM ATP2A3	1.32e-04	140	112	6	int:ACSL4
Interaction	NHS interactions	NCKAP1 CFTR RHOA KIF5B	1.46e-04	48	112	4	int:NHS
Interaction	MYO1G interactions	CFTR SIK1 E2F4	1.52e-04	19	112	3	int:MYO1G
Interaction	BLTP1 interactions	KIF7 RHOA RHOB RHOC	1.58e-04	49	112	4	int:BLTP1
Interaction	TOP3B interactions	RANBP10 KIF23 ACACA KALRN MYO7A CFAP43 SPPL2B THOC2 REXO1 RHOA CPTP RHOC CCDC88C IGF2R CELSR2 HERC2 KLHL14 DNMBP ATP2A3 UVRAG	1.60e-04	1470	112	20	int:TOP3B
Interaction	B2M interactions	CFTR HLA-G RHOA RHOB RHOC	1.62e-04	92	112	5	int:B2M
Interaction	CEP89 interactions	KIF7 RHOA RHOB RHOC CCDC88C SLC25A12	1.72e-04	147	112	6	int:CEP89
Interaction	KIF27 interactions	KIF23 LRRIQ1 HYDIN	1.78e-04	20	112	3	int:KIF27
Interaction	SLC6A9 interactions	THOC2 RHOA RHOB	1.78e-04	20	112	3	int:SLC6A9
Interaction	GNA13 interactions	ISOC1 RHOA RHOB RHOC GNA13 HERC2	1.79e-04	148	112	6	int:GNA13
Interaction	TMEM277P interactions	CFTR E2F4	1.82e-04	4	112	2	int:TMEM277P
Interaction	PPFIA1 interactions	KIF7 RHOA RHOB RHOC IPO9 HERC2 KDM1A	1.95e-04	214	112	7	int:PPFIA1
Interaction	PAK2 interactions	ISOC1 ECM1 RGS4 RHOA RHOB RHOC USP4	2.06e-04	216	112	7	int:PAK2
Interaction	CRIM1 interactions	RHOA RHOB RHOC	2.07e-04	21	112	3	int:CRIM1
Interaction	TJP2 interactions	KIF23 ACACA CFTR RHOA RHOB RHOC DNMBP RPAP2	2.08e-04	288	112	8	int:TJP2
Interaction	CAVIN1 interactions	KIF23 CFTR CLOCK RHOA RHOB RHOC HERC2 KDM1A	2.28e-04	292	112	8	int:CAVIN1
Interaction	COPB1 interactions	KIF23 ACACA CFTR HLA-G SKI RGS4 IPO9 IRAK3	2.39e-04	294	112	8	int:COPB1
Interaction	RAP2C interactions	KIF23 RHOA RHOB RHOC	2.48e-04	55	112	4	int:RAP2C
Interaction	TNIK interactions	NCKAP1 KALRN KIF7 RHOB KIF2A KIF5B CTNNA2 HERC2 KDM1A	2.78e-04	381	112	9	int:TNIK
Interaction	GIMAP4 interactions	CFTR GNA13	3.03e-04	5	112	2	int:GIMAP4
Interaction	RICTOR interactions	B4GALT2 KIF23 CIB2 ACOT9 CPT1A RHOA RHOB RHOC IPO9 IGF2R FBXW5 KIF5B NCKAP1L	3.04e-04	759	112	13	int:RICTOR
Interaction	MED19 interactions	MED16 POLR2G GTF2B HERC2 RPAP2	3.14e-04	106	112	5	int:MED19
Interaction	RRAS2 interactions	KIF23 PGGT1B RHOA RHOB RHOC	3.58e-04	109	112	5	int:RRAS2
Interaction	WDR6 interactions	B4GALT2 KMT2E FMNL2 RHOA RHOB RHOC KLHL14 KDM1A	3.71e-04	314	112	8	int:WDR6
Interaction	BMPR2 interactions	RHOA RHOB RHOC LRRIQ1 OC90	3.73e-04	110	112	5	int:BMPR2
Interaction	YWHAH interactions	KIF21B KIF23 NCKAP1 CFTR ISOC1 SIK1 KIF7 CCDC88C IPO9 USP4 KIF2A KIF5B PLCH1 DNMBP UVRAG NIN	3.85e-04	1102	112	16	int:YWHAH
Interaction	SLITRK4 interactions	RHOA RHOB RHOC	3.96e-04	26	112	3	int:SLITRK4
Interaction	FXR1 interactions	KIF23 VWF KIF21A E2F4 THOC2 ECM1 KIF7 RHOA KIF2A HERC2 PCCB KIF17	3.96e-04	679	112	12	int:FXR1
Interaction	HACD3 interactions	ACACA CFTR SPPL2B FMNL2 RHOA RHOB RHOC	4.10e-04	242	112	7	int:HACD3
Interaction	MYO9B interactions	KIF23 RHOA RHOB RHOC HERC2	4.22e-04	113	112	5	int:MYO9B
Interaction	PREX2 interactions	KALRN RHOA DNMBP	4.43e-04	27	112	3	int:PREX2
Interaction	ZNFX1 interactions	B4GALT2 CIB2 FBXW5 KLHL14	4.44e-04	64	112	4	int:ZNFX1
Interaction	CCDC77 interactions	MCPH1 SYT12 KIF7 NIN	4.44e-04	64	112	4	int:CCDC77
Interaction	TMEM185B interactions	RHOA RHOC	4.53e-04	6	112	2	int:TMEM185B
Interaction	MACF1 interactions	KIF23 KALRN CFTR RHOA RHOB RHOC HERC2	4.64e-04	247	112	7	int:MACF1
Interaction	PPFIBP1 interactions	KIF21A FMNL2 RHOA RHOB RHOC CCDC88C	4.67e-04	177	112	6	int:PPFIBP1
Interaction	YWHAB interactions	KIF21B KIF23 SPARC NCKAP1 CFTR SIK1 CCDC88C IPO9 USP4 KIF2A KIF5B PLCH1 DNMBP MAP2K6 UVRAG	4.90e-04	1014	112	15	int:YWHAB
Interaction	B3GALT6 interactions	MCPH1 SPPL2B ATP2A3	4.95e-04	28	112	3	int:B3GALT6
Interaction	ARHGEF12 interactions	RHOA RHOB RHOC GNA13 HERC2	4.95e-04	117	112	5	int:ARHGEF12
Interaction	YWHAG interactions	KIF21B KIF23 SPARC NCKAP1 CFTR SIK1 KIF7 RHOA RHOB RHOC CCDC88C IPO9 KIF2A KIF5B PLCH1 DNMBP UVRAG	5.20e-04	1248	112	17	int:YWHAG
Interaction	MED20 interactions	MED16 POLR2G THOC2 RHOA C3 RPAP2	5.26e-04	181	112	6	int:MED20
Interaction	LGALS1 interactions	KIF23 CFTR IGF2R CELSR2 FBXW5 USP4 ALCAM PARM1	5.37e-04	332	112	8	int:LGALS1
Interaction	ROCK2 interactions	NCKAP1 SPPL2B RHOA RHOB RHOC KCNJ2	5.42e-04	182	112	6	int:ROCK2
Interaction	DOCK7 interactions	KIF23 CIB2 FMNL2 RHOA RHOB HERC2 KDM1A	5.48e-04	254	112	7	int:DOCK7
Interaction	PFN1 interactions	CFTR FMNL2 KIF7 RHOA RHOB RHOC USP4 KIF2A DNMBP RPAP2	5.48e-04	509	112	10	int:PFN1
Interaction	SYT12 interactions	SYT12 CFTR ATP2A3	5.50e-04	29	112	3	int:SYT12
Interaction	SOWAHC interactions	RHOA RHOB RHOC	5.50e-04	29	112	3	int:SOWAHC
Interaction	FLRT2 interactions	RHOA RHOB RHOC	5.50e-04	29	112	3	int:FLRT2
Interaction	OLR1 interactions	RHOA RHOB RHOC	5.50e-04	29	112	3	int:OLR1
Interaction	PRPF18 interactions	THOC2 BLZF1 FMNL2 FMNL3 GTF2B	5.56e-04	120	112	5	int:PRPF18
Interaction	MFAP3 interactions	SYT12 RHOA RHOB RHOC	5.60e-04	68	112	4	int:MFAP3
Interaction	DIAPH2 interactions	FMNL2 FMNL3 RHOA RHOB	5.60e-04	68	112	4	int:DIAPH2
Interaction	RALGAPB interactions	ACACA RHOA RHOB GFOD1	5.60e-04	68	112	4	int:RALGAPB
Interaction	SURF4 interactions	KIF23 CFTR SPPL2B THOC2 HERC2 ATP2A3	5.74e-04	184	112	6	int:SURF4
Interaction	SPTBN1 interactions	KIF23 NCKAP1 KALRN CFTR RHOA RHOB RHOC KIF2A HERC2	5.74e-04	421	112	9	int:SPTBN1
Interaction	FMNL2 interactions	FMNL2 FMNL3 RHOA RHOB RHOC IGF2R	5.90e-04	185	112	6	int:FMNL2
Interaction	EHD2 interactions	E2F4 RHOA RHOB RHOC	5.92e-04	69	112	4	int:EHD2
Interaction	RBBP8 interactions	THOC2 KIF7 USP4 CTNNA2 KDM1A	5.99e-04	122	112	5	int:RBBP8
Interaction	TGFBR1 interactions	HLA-G SKI RHOA RHOB RHOC GNA13 USP4	6.01e-04	258	112	7	int:TGFBR1
Interaction	ARHGAP8 interactions	CFTR ISOC1 RHOA	6.08e-04	30	112	3	int:ARHGAP8
Interaction	CMIP interactions	RHOB RHOC GNA13	6.08e-04	30	112	3	int:CMIP
Interaction	GNB4 interactions	CFTR RHOA RHOB RHOC GNA13	6.22e-04	123	112	5	int:GNB4
Interaction	EPB41L1 interactions	ACACA NCKAP1 RHOA RHOB RHOC KIF5B	6.24e-04	187	112	6	int:EPB41L1
Interaction	KIDINS220 interactions	FMNL2 RHOA RHOB RHOC CSF1R KIF5B	6.24e-04	187	112	6	int:KIDINS220
Cytoband	17q24.3	KCNJ2 GNA13 MAP2K6	9.63e-06	17	113	3	17q24.3
Cytoband	11q13.5	MYO7A NEU3 UVRAG	1.87e-05	21	113	3	11q13.5
Cytoband	Ensembl 112 genes in cytogenetic band chr16q22	RANBP10 KCTD19 E2F4 HSD11B2 HYDIN	9.44e-05	183	113	5	chr16q22
Cytoband	1p36.12	TCEA3 KIF17 KDM1A	1.24e-04	39	113	3	1p36.12
Cytoband	Ensembl 112 genes in cytogenetic band chr17q24	KCNJ2 GNA13 MAP2K6	1.86e-03	98	113	3	chr17q24
GeneFamily	Kinesins\|Pleckstrin homology domain containing	KIF21B KIF23 KIF21A KIF7 KIF2A KIF5B KIF17	4.55e-10	46	70	7	622
GeneFamily	Rho family GTPases	RHOA RHOB RHOC	6.04e-05	20	70	3	390
GeneFamily	EF-hand domain containing	CIB2 SLC25A12 GUCA1A PLCH1 NIN	1.59e-03	219	70	5	863
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	KALRN ARHGEF33 DNMBP	2.14e-03	66	70	3	722
GeneFamily	WD repeat domain containing	KIF21B MED16 KIF21A CFAP43 FBXW5	3.46e-03	262	70	5	362
GeneFamily	PHD finger proteins\|Lysine demethylases	KDM4D KDM1A	3.86e-03	24	70	2	485
Coexpression	VERRECCHIA_EARLY_RESPONSE_TO_TGFB1	SPARC RHOA RHOB RHOC IGF2R	3.64e-06	54	113	5	M4737
Coexpression	TABULA_MURIS_SENIS_BROWN_ADIPOSE_TISSUE_ENDOTHELIAL_CELL_AGEING	HLA-G OSGEP KMT2E BBS9 RHOB RHOC GTF2B CSF1R	6.77e-06	228	113	8	MM3676
Coexpression	FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_UP	POLR2G ISOC1 ECM1 FMNL2 RHOC GFOD1 C3 KIF2A ALCAM KIF5B MAP2K6 ATP2A3	8.70e-06	585	113	12	M6659
Coexpression	GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_4H_DN	HLA-G PSMB9 REXO1 RHOB GTF2B CSF1R ALCAM	2.64e-05	200	113	7	M9641
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCTD19 CFTR CHRNB3 MOV10L1 PKHD1 CTNNA2 HYDIN	1.77e-07	160	113	7	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCTD19 CFTR CHRNB3 MOV10L1 PKHD1 CTNNA2 HYDIN	1.77e-07	160	113	7	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	droplet-Marrow-nan-3m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMNL2 CSF1R IRAK3 C3 SERAC1 ALCAM NIN	3.26e-07	175	113	7	cf53a15bfb37b6019e7052ffdf594a9ac040900e
ToppCell	COVID_vent-Myeloid-Monocytic-CD16+_Monocyte\|COVID_vent / Disease condition, Lineage, Cell class and subclass	FMNL2 RHOB RHOC CSF1R IRAK3 C3 MS4A14	6.53e-07	194	113	7	b133d3d198360269cc449a75d34c29be377d91e0
ToppCell	LPS_only-Epithelial_airway-airway_epithelial-Ciliated\|LPS_only / Treatment groups by lineage, cell group, cell type	RANBP10 MYO7A DCDC2B ARHGEF33 LRRIQ1 PLCH1 HYDIN	7.49e-07	198	113	7	6d90b541fde357fbb40f8f7d4e8628a48b679718
ToppCell	Tracheal-NucSeq-Endothelial-Endothelia_vascular-VE_alveolar_capillary_Car4_aerocyte\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	KIF23 VWF KALRN ECM1 RHOC GFOD1 GNA13	8.01e-07	200	113	7	fe493b0454a20498e9ada482bf55de64519f6c35
ToppCell	Smart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_dendritic-CD1c-positive_myeloid_dendritic_cell\|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ACOT9 FMNL2 GNA13 MS4A14 ALCAM DNMBP	4.82e-06	170	113	6	cc66ac6846c58be9493eb270644ee3ce0f86cfea
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KIF21A CFTR GPC6 C3 PLCH1 PARM1	6.68e-06	180	113	6	b798a3fa2dd15b68aa4267f665559527043dcc07
ToppCell	Control-Epithelial_alveolar-AT_2-Differentiating_AT2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KIF21A CFTR GPC6 C3 PLCH1 PARM1	7.82e-06	185	113	6	0d2add28ac1f4fa6de7699be009bf8391badaf4c
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KIF21A CFTR GPC6 C3 PLCH1 PARM1	7.82e-06	185	113	6	fefaf227d89f680d6f3e91c4a94e26ab4d0dc6c3
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_2-AT2_Progenitor\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KIF21A CFTR GPC6 C3 PLCH1 PARM1	7.82e-06	185	113	6	929b68b05b7686341329ac756d7df172cb4b810b
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VWF HLA-G FMNL3 RHOB CCDC88C KCNJ2	7.82e-06	185	113	6	602536a3308a848f106adcb0a83530997440c8f4
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KIF21A CFTR GPC6 C3 PLCH1 PARM1	8.57e-06	188	113	6	4bdf8d49af0e9da349b16e3f012e1b0eec04cc4f
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D175\|Adult / Lineage, Cell type, age group and donor	ACACA CFTR KCNJ2 C3 PLCH1 PARM1	8.57e-06	188	113	6	ec38def1fdbb34ed9b30244806975bd5a4370164
ToppCell	COPD-Myeloid-ncMonocyte\|Myeloid / Disease state, Lineage and Cell class	RHOC CCDC88C GFOD1 IRAK3 DNMBP NIN	9.10e-06	190	113	6	ed978cd5d9da87b49878a330e362762c487f849f
ToppCell	COVID-19-lung-AT2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ACACA CFTR C3 ALCAM PLCH1 PARM1	9.10e-06	190	113	6	27a1a86620fe9b5ee930d388b32352206485e6d0
ToppCell	PCW_07-8.5-Epithelial-Epithelial_proliferating\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	KCTD19 KIF21A LRRIQ1 PKHD1 HSD11B2 PLCH1	9.66e-06	192	113	6	1aa5e4d9b32013a3f272561dcb8377f6805706df
ToppCell	healthy_donor-Myeloid-Monocytic-CD16+_Monocyte\|healthy_donor / Disease condition, Lineage, Cell class and subclass	FMNL2 RHOB RHOC CSF1R IRAK3 C3	1.02e-05	194	113	6	ecf746ef1c5c4d6d9ca06a6d3e3778670b5700c2
ToppCell	COVID-19_Severe-Non-classical_Monocyte-\|COVID-19_Severe / Disease condition and Cell class	FMNL2 RHOB RHOC CCDC88C CSF1R C3	1.02e-05	194	113	6	d70b9039fd2fef3e4be086513b94fb7e9bc1f670
ToppCell	COVID-19_Severe-Non-classical_Monocyte\|COVID-19_Severe / Disease condition and Cell class	FMNL2 RHOB RHOC CCDC88C CSF1R C3	1.02e-05	194	113	6	5151546812678ae85cb22224084d27b29e3c4724
ToppCell	PCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^medium_distal_(2)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	KCTD19 LRRIQ1 PKHD1 HSD11B2 PLCH1 PARM1	1.06e-05	195	113	6	f08e41706680881ebd0afcd08a02f8ac0089f04e
ToppCell	PCW_10-12-Epithelial-Epithelial_proliferating\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	KIF21A LRRIQ1 PKHD1 HSD11B2 PLCH1 PARM1	1.06e-05	195	113	6	ce1ba5911e8a6ddb07434acc37147c38e94245ff
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	RHOB GTF2B CSF1R GNA13 C3 MS4A14	1.06e-05	195	113	6	562e4c0e4e81f6303e57b846da71d1667fc35963
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	RHOB GTF2B CSF1R GNA13 C3 MS4A14	1.06e-05	195	113	6	fa8ac154e5aebc26463ff84f0ad1038095770bc6
ToppCell	COVID-19_Severe-Non-classical_Monocyte\|COVID-19_Severe / disease group, cell group and cell class	FMNL2 RHOC CSF1R IRAK3 C3 MS4A14	1.09e-05	196	113	6	af9e8f5ef9d03862f707e105857309b55595b1b9
ToppCell	COVID-19-lung-Macrophage_CD163hi_MERTKhi\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FMNL2 CSF1R GNA13 IRAK3 ALCAM NCKAP1L	1.09e-05	196	113	6	7026c1fc33425e5476063d17c79e4b79356a9e01
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SPARC VWF KALRN FMNL3 GFOD1 IRAK3	1.12e-05	197	113	6	0f467ef58f0c4dcc00b34b7b9639e03fb3ebe780
ToppCell	COVID-19_Severe-Myeloid-Non-classical_Monocyte\|COVID-19_Severe / Disease group, lineage and cell class	FMNL2 RHOB RHOC CSF1R IRAK3 C3	1.12e-05	197	113	6	c5837b9a5a39a0f607a4e217ade9fc87d82a5406
ToppCell	wk_20-22-Epithelial\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	KIF21A DCDC2B CFAP43 LRRIQ1 ALCAM HYDIN	1.12e-05	197	113	6	468071c1911cdf8e8806a78dbceb95379e28ae91
ToppCell	COVID-19_Severe-PLT_2\|World / Disease Group and Platelet Clusters	SPARC RHOC CCDC88C IGHM KIF2A ATP2A3	1.12e-05	197	113	6	b6267c624c2e0070c34bba54bf5362466a2dbf34
ToppCell	PBMC-Severe-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FMNL2 RHOB RHOC CSF1R IRAK3 C3	1.15e-05	198	113	6	9b8679b3dd8f4220d71f607b7080cb88d6e71129
ToppCell	PBMC-Severe-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FMNL2 RHOB RHOC CSF1R IRAK3 C3	1.15e-05	198	113	6	8b6b602ebe59b6dca6a22f17385d3160ff3ac67e
ToppCell	COVID-19-Myeloid\|COVID-19 / group, cell type (main and fine annotations)	FMNL2 CSF1R GNA13 IRAK3 ALCAM NCKAP1L	1.15e-05	198	113	6	33f0a919188a67d2a876b52c61a1cec2c9747969
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SPARC VWF KALRN FMNL3 GFOD1 IRAK3	1.15e-05	198	113	6	1378c6d4ceb84b42fdd6556be3296df7a8059e6e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SPARC VWF KALRN FMNL3 GFOD1 IRAK3	1.15e-05	198	113	6	451003a21162eeae90739fdb502bb50b362d80c8
ToppCell	PBMC-Severe-Myeloid-Non-classical_Monocyte\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FMNL2 RHOB RHOC CSF1R IRAK3 C3	1.15e-05	198	113	6	b9030390316baf456135f85f831394e1e11ecf3e
ToppCell	PBMC-Severe-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	FMNL2 RHOB RHOC CSF1R IRAK3 C3	1.15e-05	198	113	6	d36a3cda7e5f385d2391e9b0dfb027d3c4549320
ToppCell	PBMC-Severe-Myeloid-Non-classical_Monocyte\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	FMNL2 RHOB RHOC CSF1R IRAK3 C3	1.15e-05	198	113	6	5436c3ed16e10e00c686f1ab0b0a68728a1a9985
ToppCell	severe_influenza-Non-classical_Monocyte\|World / disease group, cell group and cell class (v2)	FMNL2 RHOB RHOC CSF1R IRAK3 C3	1.15e-05	198	113	6	790ee20abc9666b8095675b0d445c0914ee70ea3
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SPARC VWF KALRN FMNL3 GFOD1 IRAK3	1.15e-05	198	113	6	440af8f90c7afa1c07000806bcf9110b70f489fb
ToppCell	PBMC-Severe-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	FMNL2 RHOB RHOC CSF1R IRAK3 C3	1.15e-05	198	113	6	4f67067d8142ca11b2d80195dac8d62a8d24d52c
ToppCell	COVID-19-COVID-19_Severe-Myeloid-CD16+_Monocyte\|COVID-19_Severe / Disease, condition lineage and cell class	FMNL2 RHOB RHOC CSF1R IRAK3 C3	1.22e-05	200	113	6	58fbb7fc7159cbc417e6b457d60b7beba9b90da6
ToppCell	mild-Non-classical_Monocyte\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	FMNL2 RHOB RHOC CSF1R IRAK3 C3	1.22e-05	200	113	6	692b48da9fd56bafcb3c8b33b0fe369160881c45
ToppCell	severe-Non-classical_Monocyte\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	FMNL2 RHOB RHOC CSF1R IRAK3 C3	1.22e-05	200	113	6	6cc7190a4ffc6c06335072f3b5b5f98eae36e2ce
ToppCell	normal_Pleural_Fluid-B_lymphocytes-Plasma_cells\|normal_Pleural_Fluid / Location, Cell class and cell subclass	CIB2 ACACA IGHM SERAC1 ALCAM	2.19e-05	132	113	5	4e37400ae7375e6986f060234c373194603346f8
ToppCell	normal_Pleural_Fluid-B_lymphocytes-Plasma_cells\|B_lymphocytes / Location, Cell class and cell subclass	CIB2 ACACA SERAC1 ALCAM MAP2K6	4.45e-05	153	113	5	a156710217ef07c07a80ca6504fa0784d86380fa
ToppCell	10x5'-Lung-Lymphocytic_T_CD4-T_CD4/CD8\|Lung / Manually curated celltypes from each tissue	ANO9 KIF21A CFAP43 LRRIQ1 PLCH1	4.88e-05	156	113	5	10d191e29b16cae8238e8df6c0ff38882253f34e
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_E\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	MYO7A GPC6 FMNL2 LRRIQ1 IRAK3	5.03e-05	157	113	5	432b8719a8afd289cf48068e12c26a349d753fcc
ToppCell	COVID-19-kidney-Epithelial_(EC)\|kidney / Disease (COVID-19 only), tissue and cell type	VWF KALRN GFOD1 IRAK3 CTNNA2	5.50e-05	160	113	5	0d4880f85565d8c540c94a8f8109147b3029279a
ToppCell	Ciliated_cells-A-Donor_01\|World / lung cells shred on cell class, cell subclass, sample id	DCDC2B CFAP43 GUCA1A CTNNA2 HYDIN	6.01e-05	163	113	5	43194c6127df1ce3d29242f719645de3c11fd7c0
ToppCell	PBMC-Mild-Hematopoietic-Platelet-Platelet-plt_0\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SPARC NCKAP1 CFAP43 PTGES3L PLCH1	6.37e-05	165	113	5	6799a6580c667738995cceb31cbf1c7fbdc4ff84
ToppCell	PBMC-Mild-Hematopoietic-Platelet-Platelet-plt_0\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SPARC NCKAP1 CFAP43 PTGES3L PLCH1	6.37e-05	165	113	5	8329d780f244bc31344443b29e5a00529a016662
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FMNL3 CSF1R C3 RPAP2 NCKAP1L	6.74e-05	167	113	5	942134bbabe9972fae80cbc4ed4e94da52f55dc3
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DCDC2B CFAP43 CCDC88C LRRIQ1 HYDIN	7.13e-05	169	113	5	14aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCell	ASK452-Endothelial-Endothelium\|Endothelial / Donor, Lineage and Cell class of Lung cells from Dropseq	SPARC VWF RHOB	7.26e-05	32	113	3	fd0777da59e8ac3e0f766071977cb169d058e5ae
ToppCell	facs-Lung-EPCAM-18m-Endothelial-Vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF MCPH1 BLZF1 ZFAND4 GFOD1	7.33e-05	170	113	5	12203d4410f38cc933d9f160b5fb76828df94119
ToppCell	facs-Lung-EPCAM-18m-Endothelial-vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF MCPH1 BLZF1 ZFAND4 GFOD1	7.33e-05	170	113	5	f9decb3bf3bf6d4996b0ac27af768236e116aac5
ToppCell	facs-Heart-RA-18m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KALRN NEU3 RGS4 CELSR2 PARM1	7.54e-05	171	113	5	b54d9d6b03c9c6f28a71cf2ed2bfa9a335bba949
ToppCell	facs-Heart-RA-18m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KALRN NEU3 RGS4 CELSR2 PARM1	7.54e-05	171	113	5	9d825a2e799421af4f2cf4f4dc8e239b5d00476d
ToppCell	facs-Lung-EPCAM-24m-Lymphocytic-lymphocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACACA ISOC1 DCDC2B BBS9 PCCB	7.96e-05	173	113	5	6e92983d9f8a2a37f23e60a0d5bb1738217897bc
ToppCell	droplet-Fat-Gat-18m-Epithelial\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFTR CFAP43 TMEM132B PLCH1 HYDIN	7.96e-05	173	113	5	f3f67531f72d6d52e19c7f1f2db1ab4026fb70da
ToppCell	droplet-Fat-Gat-18m-Epithelial-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFTR CFAP43 TMEM132B PLCH1 HYDIN	7.96e-05	173	113	5	a40a52d8041d45dc3bef74fe55945ae07aa018d6
ToppCell	droplet-Fat-Gat-18m-Epithelial-epithelial_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFTR CFAP43 TMEM132B PLCH1 HYDIN	7.96e-05	173	113	5	f0b4dd1cf41d6ee6abb0e1968b8b39f4fabebcb5
ToppCell	facs-Lung-EPCAM-24m-Lymphocytic-Alox5+_Lymphocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACACA ISOC1 DCDC2B BBS9 PCCB	7.96e-05	173	113	5	4c788c1dad1da495b3b5c10f95e779848dfe85dc
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SPARC PTGES3L GPC6 RGS4 PARM1	8.18e-05	174	113	5	778e0317c0c63fa4efd74114feb760975b819d92
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW09-OPC_related\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	KALRN OSGEP IGF2R HSD11B2	8.52e-05	91	113	4	25197fde8b9bdaf1e28add695d13aff3ff52d86e
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW09-OPC_related-Oligodendrocyte/OPC\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	KALRN OSGEP IGF2R HSD11B2	8.52e-05	91	113	4	ed4a48e5e5f5d8aadbc7b1b8d84a5f6363a08b85
ToppCell	facs-Heart-LA-24m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMCO5A KALRN RGS4 DNMBP PARM1	8.87e-05	177	113	5	32fecefba1a55e1f418c9a055236fa11175c692d
ToppCell	facs-Heart-LA-24m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMCO5A KALRN RGS4 DNMBP PARM1	8.87e-05	177	113	5	1b153fbfe1323dc589de4af73a52149ea5ce6763
ToppCell	10x5'v1-week_14-16-Myeloid_macrophage-stroma-monocytoid_macrophage\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	AMER2 CSF1R C3 MS4A14 PARM1	8.87e-05	177	113	5	945b2d0723a0a35c767604ae607d2c2d53bf0c82
ToppCell	LPS-IL1RA+antiTNF-Myeloid-Monocytes,_Macrophages-Neutrophils\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ACOT9 SNUPN RHOA IGHM PLCH1	8.87e-05	177	113	5	2dd6dd5193bda9ba1c6b299ec47890fdc92f88b1
ToppCell	droplet-Liver-Npc-18m-Lymphocytic-macrophage/monocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF MCPH1 SIK1 MAP2K6 ATP2A3	9.10e-05	178	113	5	09d2687e0d79f12e90af35fc1c0453d249cf2d19
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Epithelial\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFTR TMEM132B LRRIQ1 PLCH1 HYDIN	9.10e-05	178	113	5	58857bb8c13e0e1c6d9f5c1258f00fff62063d68
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Epithelial-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFTR TMEM132B LRRIQ1 PLCH1 HYDIN	9.10e-05	178	113	5	8b7df6ab8709d9ab9dff97677cc4561aec2745bc
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Epithelial-epithelial_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFTR TMEM132B LRRIQ1 PLCH1 HYDIN	9.10e-05	178	113	5	b0baf5667e3301898b3e45e974b8a8530af6a338
ToppCell	LPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KIF21A GPC6 C3 PLCH1 PARM1	9.35e-05	179	113	5	fd2cbee532e7b44113410dca82aec7db1a7fb69f
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_2-AT2_Progenitor\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CFTR GPC6 C3 PLCH1 PARM1	9.35e-05	179	113	5	7db6b97a1c4c7a163d5da4351ba36ac1785d9d7b
ToppCell	5'-Airway_Nasal-Mesenchymal-Fibroblastic\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SPARC ECM1 RGS4 KIF7 GUCA1A	9.60e-05	180	113	5	935c091bbcd6d10b81dc4731779e5bd98205c99f
ToppCell	5'-Airway_Nasal-Mesenchymal\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SPARC ECM1 RGS4 KIF7 GUCA1A	9.60e-05	180	113	5	3dd384b7f3d9582b8fec9fe05100e466e6218b76
ToppCell	E15.5-Mesenchymal-myocytic_cell-vascular_associated_smooth_muscle_cell\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SPARC PTGES3L RHOC IGF2R PARM1	9.60e-05	180	113	5	38035cf2c6fbc443ea10ca7e942572715ed572da
ToppCell	E18.5-samps-Mesenchymal-Pericyte\|E18.5-samps / Age Group, Lineage, Cell class and subclass	NCKAP1 ECM1 RGS4 SMTN PARM1	9.60e-05	180	113	5	0b1d370db64862fe1c7ea0ffaf06d03ec82e6e70
ToppCell	LPS_only-Epithelial_alveolar-AT_2-AT2_Progenitor\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KIF21A CFTR GPC6 PLCH1 PARM1	9.85e-05	181	113	5	0513b9e6673ff7bf8e72ba123ca3794b65d10170
ToppCell	facs-GAT-Fat-3m-Epithelial-epithelial_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM132B LRRIQ1 PKHD1 PLCH1 HYDIN	9.85e-05	181	113	5	e97cbaafb93fdbee8e3cf4a06e6bcf121d941403
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANO9 SPARC NEU3 C1RL C3	9.85e-05	181	113	5	330d4322f4c4373f706273c1f4e218b59051b7fd
ToppCell	facs-Marrow-Granulocytes-3m-Lymphocytic-mature_alpha-beta_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPARC NCKAP1 SPPL2B CLOCK PKHD1	9.85e-05	181	113	5	41969fe4d94ee77b12ecde32170aaf0b13e49644
ToppCell	facs-Marrow-Granulocytes-3m-Lymphocytic-BM_CD8_+_CD4_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPARC NCKAP1 SPPL2B CLOCK PKHD1	9.85e-05	181	113	5	3f50e61dc2a52d71a5801584617607e6246adcf2
ToppCell	facs-GAT-Fat-3m-Epithelial\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM132B LRRIQ1 PKHD1 PLCH1 HYDIN	9.85e-05	181	113	5	11cb84528f7ca084f0a92eda4f2e18e63a428fe9
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANO9 SPARC NEU3 C1RL C3	9.85e-05	181	113	5	3f4d5d79c1286614514b0e8134079d6128a2a23e
ToppCell	facs-GAT-Fat-3m-Epithelial-nan\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM132B LRRIQ1 PKHD1 PLCH1 HYDIN	9.85e-05	181	113	5	5ffeca29e4d31a20c110d27af128ed024a79ad56
ToppCell	nucseq-Immune-Lymphocytic_B-Lymphocytic_B-B\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	IGHM KLHL14 ATP2A3 UVRAG NIN	9.85e-05	181	113	5	8d8cc4dae2c8bd5f4b1c159f2a52edc4c9449c86
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KIF21A GPC6 C3 PLCH1 PARM1	1.01e-04	182	113	5	17ed11a7ea366dd3106400511d5e628d3f1a9c3e
ToppCell	5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SPARC ECM1 RGS4 KIF7 GUCA1A	1.04e-04	183	113	5	803376f5260de83c48d4f7301278d078a32b3e6e
ToppCell	5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SPARC ECM1 RGS4 KIF7 GUCA1A	1.04e-04	183	113	5	6d98973098c6d20c5305bce6a83a549a7d8dbfba
ToppCell	droplet-Lung-LUNG-30m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF21A CFAP43 LRRIQ1 PLCH1 HYDIN	1.04e-04	183	113	5	3991830726d05cf19606d540de04093985b7bdeb
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L5-6_SST_ISOC1\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ISOC1 GPC6 KLHL14 PLCH1 PARM1	1.04e-04	183	113	5	7961e05c6e9964da159059c6bfb4f7e7e14308c2
ToppCell	5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SPARC ECM1 RGS4 KIF7 GUCA1A	1.04e-04	183	113	5	cc7f5a17b40e8d901885174922e5fa8877643071
ToppCell	droplet-Lung-LUNG-30m-Epithelial-Ciliated_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF21A CFAP43 LRRIQ1 PLCH1 HYDIN	1.04e-04	183	113	5	cc844f54c7564bf432b179ca63bc7c4b9b8cfdd9
ToppCell	E15.5-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	TCEA3 CIB2 SPARC ECM1 ALCAM	1.04e-04	183	113	5	274f274cf60daa30d6a4cd603a3af7823bfb8016
ToppCell	LPS_only-Epithelial_alveolar-AT_2\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KIF21A GPC6 C3 PLCH1 PARM1	1.04e-04	183	113	5	e972432dd4d1bd31bb0982f4df3061e5e152658f
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KALRN CFTR PKHD1 PLCH1 HYDIN	1.06e-04	184	113	5	2cbed6462fea2622871bb7e49b0df3d984239281
Drug	Thyroxine (L) [51-48-9]; Up 200; 5.2uM; PC3; HT_HG-U133A	MCPH1 SYT12 MED16 ST7L RGS4 CSF1R PLCH1 ATP2A3	6.42e-06	197	113	8	4069_UP
Drug	Guanethidine sulfate [60-02-6]; Down 200; 13.4uM; PC3; HT_HG-U133A	CIB2 MED16 C1RL CPT1A BBS9 CCDC88C KDM4D RPAP2	6.66e-06	198	113	8	5731_DN
Drug	Spectinomycin dihydrochloride [21736-83-4]; Down 200; 9.8uM; HL60; HT_HG-U133A	B4GALT2 CPT1A SPPL2B BLZF1 PGGT1B GFOD1 GNA13 NCKAP1L	6.91e-06	199	113	8	2987_DN
Disease	ulcerative colitis (implicated_via_orthology)	RHOA RHOB RHOC	1.84e-06	7	112	3	DOID:8577 (implicated_via_orthology)
Disease	peroxisomal biogenesis disorder (implicated_via_orthology)	RHOA RHOB RHOC	2.94e-06	8	112	3	DOID:0080377 (implicated_via_orthology)
Disease	intraocular pressure measurement	TMCO5A MCPH1 KALRN ISOC1 ST7L FMNL2 BBS9 GTF2B PKHD1 ALCAM HERC2	3.95e-06	509	112	11	EFO_0004695
Disease	hypertension (biomarker_via_orthology)	VWF CLOCK RGS4 RHOA C3 HSD11B2 ATP2A3	2.66e-05	227	112	7	DOID:10763 (biomarker_via_orthology)
Disease	Ciliopathies	MYO7A CFTR BBS9 KIF7 PKHD1	6.42e-05	110	112	5	C4277690
Disease	microglial activation measurement	CCDC88C ALCAM CTNNA2 KIF17	7.62e-05	59	112	4	EFO_0010940
Disease	breast cancer (is_marker_for)	KMT2E RHOA RHOB RHOC CSF1R KDM1A	7.73e-05	185	112	6	DOID:1612 (is_marker_for)
Disease	Choledochal Cyst, Type I	CFTR PKHD1	1.42e-04	5	112	2	C0009439
Disease	Choledochal Cyst, Type II	CFTR PKHD1	1.42e-04	5	112	2	C1257796
Disease	Choledochal Cyst, Type III	CFTR PKHD1	1.42e-04	5	112	2	C1257797
Disease	Choledochal Cyst, Type IV	CFTR PKHD1	1.42e-04	5	112	2	C1257798
Disease	Choledochal Cyst, Type V	CFTR PKHD1	1.42e-04	5	112	2	C1257799
Disease	Choledochal Cyst	CFTR PKHD1	1.42e-04	5	112	2	C0008340
Disease	central corneal thickness	ISOC1 ST7L SKI BBS9 GTF2B HERC2 PCCB	1.83e-04	309	112	7	EFO_0005213
Disease	v-set and transmembrane domain-containing protein 4 measurement	MED16 C3	2.12e-04	6	112	2	EFO_0803247
Disease	Usher Syndrome, Type I	CIB2 MYO7A	2.12e-04	6	112	2	C1568247
Disease	neuroimaging measurement	KIF21B TMCO5A MCPH1 ST7L BBS9 CHRNB3 CCDC88C AMER2 LRRIQ1 GNA13 PKHD1 ALCAM PLCH1	2.12e-04	1069	112	13	EFO_0004346
Disease	Cerebral ventriculomegaly	CCDC88C HYDIN	2.96e-04	7	112	2	C1531647
Disease	regulator of G-protein signaling 8 measurement	MED16 C3	2.96e-04	7	112	2	EFO_0801997
Disease	Hydrocephalus Ex-Vacuo	CCDC88C HYDIN	2.96e-04	7	112	2	C0270720
Disease	Communicating Hydrocephalus	CCDC88C HYDIN	2.96e-04	7	112	2	C0009451
Disease	Fetal Cerebral Ventriculomegaly	CCDC88C HYDIN	2.96e-04	7	112	2	C2936718
Disease	Post-Traumatic Hydrocephalus	CCDC88C HYDIN	2.96e-04	7	112	2	C0477432
Disease	Obstructive Hydrocephalus	CCDC88C HYDIN	2.96e-04	7	112	2	C0549423
Disease	corneal resistance factor	ISOC1 ST7L SKI BBS9 CENPP RHOA ALCAM HERC2	3.33e-04	451	112	8	EFO_0010067
Disease	myocardial infarction	KALRN SKI ZNF77 IPO9 CELSR2 DNMBP PCCB	3.88e-04	350	112	7	EFO_0000612
Disease	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 measurement	MED16 C3	3.94e-04	8	112	2	EFO_0801373
Disease	Congenital Hydrocephalus	CCDC88C HYDIN	3.94e-04	8	112	2	C0020256
Disease	calcium/calmodulin-dependent protein kinase type 1D measurement	MED16 C3	3.94e-04	8	112	2	EFO_0008063
Disease	Aqueductal Stenosis	CCDC88C HYDIN	3.94e-04	8	112	2	C2936786
Disease	cellular retinoic acid-binding protein 1 measurement	MED16 C3	5.05e-04	9	112	2	EFO_0801463
Disease	Hydrocephalus	CCDC88C HYDIN	5.05e-04	9	112	2	C0020255
Disease	Autosomal Recessive Polycystic Kidney Disease	CFTR PKHD1	5.05e-04	9	112	2	C0085548
Disease	membranous glomerulonephritis (implicated_via_orthology)	RHOA C3	5.05e-04	9	112	2	DOID:10976 (implicated_via_orthology)
Disease	Alcoholic Intoxication, Chronic	VWF CFTR CLOCK RGS4 CHRNB3 CTNNA2	5.68e-04	268	112	6	C0001973
Disease	triglycerides in large LDL measurement	IGF2R CELSR2 PCCB	5.88e-04	43	112	3	EFO_0022319
Disease	adseverin measurement	C1RL DNMBP	6.30e-04	10	112	2	EFO_0801358
Disease	PR domain zinc finger protein 1 measurement	MED16 USP4	7.68e-04	11	112	2	EFO_0801904
Disease	Leukoencephalopathy	RHOA CSF1R	7.68e-04	11	112	2	C0270612
Disease	cocaine use	CLOCK CHRNB3	7.68e-04	11	112	2	C3496069
Disease	autosomal recessive polycystic kidney disease (biomarker_via_orthology)	CFTR PKHD1	7.68e-04	11	112	2	DOID:0110861 (biomarker_via_orthology)
Disease	response to virus	MCPH1 BBS9	7.68e-04	11	112	2	GO_0009615
Disease	lipoprotein A measurement	IGF2R CELSR2 SERAC1 PCCB	8.91e-04	112	112	4	EFO_0006925
Disease	oncostatin-M measurement	MED16 C3	9.19e-04	12	112	2	EFO_0010792
Disease	tyrosine-protein kinase ZAP-70 measurement	MED16 C3	9.19e-04	12	112	2	EFO_0020833
Disease	amyotrophic lateral sclerosis (biomarker_via_orthology)	IGF2R C3	1.08e-03	13	112	2	DOID:332 (biomarker_via_orthology)
Disease	brain measurement, neuroimaging measurement	KIF21B ST7L BBS9 CHRNB3 CCDC88C LRRIQ1 GNA13 ALCAM	1.21e-03	550	112	8	EFO_0004346, EFO_0004464
Disease	Childhood Ataxia with Central Nervous System Hypomyelinization	RHOA CSF1R	1.26e-03	14	112	2	C1858991
Disease	triglycerides in LDL measurement	IGF2R CELSR2 PCCB	1.27e-03	56	112	3	EFO_0022320
Disease	Disorder of eye	CIB2 MYO7A BBS9 KIF7 GUCA1A	1.31e-03	212	112	5	C0015397
Disease	triglycerides in IDL measurement	IGF2R CELSR2 PCCB	1.41e-03	58	112	3	EFO_0022149
Disease	triglycerides:total lipids ratio, intermediate density lipoprotein measurement	HLA-G CPT1A CELSR2 PCCB	1.42e-03	127	112	4	EFO_0008595, EFO_0020947
Disease	docosahexaenoic acid measurement	MCPH1 CPT1A CELSR2 CTNNA2	1.42e-03	127	112	4	EFO_0007761
Disease	phospholipids in VLDL measurement	IGF2R CELSR2 PCCB	1.48e-03	59	112	3	EFO_0022301
Disease	total lipids in VLDL measurement	IGF2R CELSR2 PCCB	1.56e-03	60	112	3	EFO_0022314
Disease	very low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio	HLA-G CPT1A IGF2R CELSR2 PCCB	1.61e-03	222	112	5	EFO_0008317, EFO_0020943
Disease	free cholesterol in VLDL measurement	IGF2R CELSR2 PCCB	1.63e-03	61	112	3	EFO_0022276
Disease	T-Cell Lymphoma	RHOA KDM1A	1.65e-03	16	112	2	C0079772
Disease	Global developmental delay	KMT2E SLC25A12 CTNNA2 KDM1A	1.68e-03	133	112	4	C0557874
Disease	triglycerides in medium LDL measurement	IGF2R CELSR2 PCCB	1.71e-03	62	112	3	EFO_0022322
Disease	Ulcerative Colitis	KIF21B ECM1 HERC2	1.79e-03	63	112	3	C0009324
Disease	Bardet-Biedl syndrome 1 (disorder)	BBS9 KIF7	1.87e-03	17	112	2	C2936862
Disease	free cholesterol measurement, low density lipoprotein cholesterol measurement	HLA-G CPT1A IGF2R CELSR2	1.87e-03	137	112	4	EFO_0004611, EFO_0008591
Disease	cholesterol in large VLDL measurement	IGF2R CELSR2 PCCB	1.96e-03	65	112	3	EFO_0021902
Disease	cholesterol in very large VLDL measurement	IGF2R CELSR2 PCCB	1.96e-03	65	112	3	EFO_0022230
Disease	total lipids in small VLDL	IGF2R CELSR2 PCCB	2.14e-03	67	112	3	EFO_0022148
Disease	stroke	SPARC KALRN UVRAG NIN	2.25e-03	144	112	4	EFO_0000712
Disease	neurodegenerative disease (implicated_via_orthology)	RHOA RHOB RHOC KIF5B	2.30e-03	145	112	4	DOID:1289 (implicated_via_orthology)
Disease	Congenital hernia of foramen of Morgagni	RHOA IGF2R	2.34e-03	19	112	2	C0265699
Disease	Congenital hernia of foramen of Bochdalek	RHOA IGF2R	2.34e-03	19	112	2	C0265700
Disease	hydrocephalus (implicated_via_orthology)	CELSR2 HYDIN	2.34e-03	19	112	2	DOID:10908 (implicated_via_orthology)
Disease	cholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurement	RANBP10 CPT1A IGF2R CELSR2 PCCB	2.39e-03	243	112	5	EFO_0004612, EFO_0020944
Disease	visual cortical surface area measurement	RHOC ALCAM	2.59e-03	20	112	2	EFO_0004771
Disease	triglycerides:total lipids ratio, low density lipoprotein cholesterol measurement	HLA-G CPT1A CELSR2 PCCB	2.60e-03	150	112	4	EFO_0004611, EFO_0020947
Disease	platelet-to-lymphocyte ratio	RANBP10 VWF KALRN HLA-G PSMB9 SKI	2.67e-03	363	112	6	EFO_0008446
Disease	Congenital diaphragmatic hernia	RHOA IGF2R	2.86e-03	21	112	2	C0235833
Disease	glaucoma	KALRN FMNL2 PKHD1 HERC2	2.86e-03	154	112	4	MONDO_0005041
Disease	asthma (is_implicated_in)	CFTR HLA-G IRAK3 C3	3.07e-03	157	112	4	DOID:2841 (is_implicated_in)
Disease	myocardial infarction (biomarker_via_orthology)	SPARC VWF C3 HSD11B2	3.28e-03	160	112	4	DOID:5844 (biomarker_via_orthology)
Disease	very low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio	HLA-G CPT1A IGF2R CELSR2 PCCB	3.40e-03	264	112	5	EFO_0008317, EFO_0020944
Disease	cortical thickness	MCPH1 CLOCK FMNL2 BBS9 LRRIQ1 GNA13 PKHD1 ALCAM KIF5B PLCH1 PCCB	3.41e-03	1113	112	11	EFO_0004840

Protein segments in the cluster

Peptide	Gene	Start	Entry
RCFFFPSLTLETEDM	TMCO5A	271	Q8N6Q1
SSCTMDVTFFPFDRQ	CHRNB3	151	Q05901
CFIFSDVDLVPMDDR	B4GALT2	211	O60909
DPSADRICLMFSDVT	AMER2	356	Q8N7J2
MATNIPCEVVAFSDR	CFAP43	71	Q8NDM7
ECFFDDMESIPAVTT	CFTR	831	P13569
SLDICFLRPVSFAME	ARHGEF33	651	A8MVX0
CVADPFEVTVMQDFF	C3	816	P01024
ESCDFVRAMVDPAQT	CPT1A	611	P50416
DEFCPVLDATFVMVA	ACOT9	191	Q9Y305
VRIFDEVMGCFSDSP	ACACA	1246	Q13085
MTVEFEECVKDSPRF	ACAP3	1	Q96P50
MEAGSVVRAIFDFCP	DNMBP	1	Q6XZF7
MRCVSVLRFDSSAPF	CELSR2	1241	Q9HCU4
DSFPLMEISTCETEA	ANO9	16	A1A5B4
DAELSPVATFRSCME	HSD11B2	176	P80365
IMEPTECSELSEFVS	CENPP	141	Q6IPU0
IDCEVFESRFPTTMA	ATP2A3	886	Q93084
CATATAFARMTETPI	RANBP10	271	Q6VN20
TTAYMPVDFEDCSDR	KCTD19	531	Q17RG1
RFVCSPDEVMDTIDE	KIF5B	171	P33176
TDECPIAVFMVVFQS	KCNJ2	151	P63252
QFVRFDSDSACPRME	HLA-G	56	P17693
LSCVDTFGTEMVSFV	OR8I2	186	Q8N0Y5
TPSSTVFFCCDMQER	ISOC1	111	Q96CN7
PATMVRVNATCRFEE	MOV10L1	821	Q9BXT6
ERTSIFEMSDFSCVG	MCPH1	451	Q8NEM0
VEFCSTPAEKMAETV	BLZF1	326	Q9H2G9
LRVPFVVDICSMTFE	HERC2	786	O95714
GTTVRVSFDFSCLEM	FAM182A	46	Q5T1J6
CSASPSSEMVTLEEF	CCDC88C	1661	Q9P219
TVMVADCSRFDSPDL	FBXW5	251	Q969U6
CVSPSDRDFMETLNT	KIF21B	346	O75037
SRSSVEMDCFFPLVK	KALRN	1711	O60229
VMIACVSPSSSDFDE	KIF7	321	Q2M1P5
CPEEESIIMSSFVSI	NCKAP1L	451	P55160
SCGEARVTFSMDAFV	KDM4D	311	Q6B0I6
FMETTVFCTSEDGLV	KMT2E	1116	Q8IZD2
PFECSQSEVMFLSLD	IRAK3	506	Q9Y616
MADFLPSRSVLSVCF	GNA13	1	Q14344
CELIDMETTTTFPRV	PARM1	231	Q6UWI2
MSPEECRRFTTDAIA	PSMB9	166	P28065
MLFCLTSRCPEEFES	OC90	311	Q02509
PEDLCFSLQETVFAM	OSGEP	226	Q9NPF4
ELTCDQFTFEFMTPD	BBS9	466	Q3SYG4
EFMRSKTDCATPDFV	LRRIQ1	121	Q96JM4
VCPEDESIIMSSFVN	NCKAP1	451	Q9Y2A7
DTEILPSLFMRCTTD	MED16	256	Q9Y2X0
PGSFVESDMFVEHRC	PCCB	76	P05166
PLVETIFERGMATCF	KIF2A	296	O00139
DEFLFTPVVVACMSI	CSF1R	511	P07333
SVTFSTECRMPDIAL	HYDIN	4861	Q4G0P3
CMDDVCPTEFEFVTT	GPC6	501	Q9Y625
ERVQSVDFMRTDPVC	KLHL14	276	Q9P2G3
DRMTSQEAACFPDII	KDM1A	186	O60341
ELSEIFDPTRECMSS	E2F4	351	Q16254
ETMRIASSEFADDPC	CTNNA2	101	P26232
SSMCVPDQDTAIRVF	IGHM	211	P01871
RRFPTMEAFLCEVTS	DCDC2B	31	A2VCK2
DFVECLMRFLPTEAE	FMNL3	676	Q8IVF7
AFCTLPTREVFLEAM	CPTP	161	Q5TA50
RPEVFSDNMFCVGDE	C1RL	411	Q9NZP8
DFVECLMRFLPTENE	FMNL2	731	Q96PY5
MPSFEEICVFSRTLF	MS4A14	141	Q96JA4
AINPCSDTTMTAEEF	GUCA1A	121	P43080
EFTASMESKICPFTI	IPO9	596	Q96P70
MSRFCEAEFSVKTRP	ECM1	241	Q16610
FVCMLVTEDNVFEAP	ALCAM	111	Q13740
DTDVILMCFSIDSPD	RHOC	76	P08134
VDPEFADMITVQEFC	KIF23	191	Q02241
MPTEESRSRYFLDEC	KIF17	566	Q9P2E2
DISMRTVDCPFTVTF	MAP2K6	101	P52564
VNSRPMFISAVEDCE	IGF2R	1481	P11717
FCAVPEGSENDMRFV	PGGT1B	161	P53609
VDFDSDPMEECLRIF	REXO1	606	Q8N1G1
DPMEECLRIFNESTS	REXO1	611	Q8N1G1
SFESCFMRVSLLPDE	SYT12	186	Q8IV01
IMPDRLDTSVSCFVV	UVRAG	101	Q9P2Y5
DTDVILMCFSIDSPD	RHOA	76	P61586
DTDVILMCFSVDSPD	RHOB	76	P62745
ESFGEVPSATVEMFC	SERAC1	261	Q96JX3
MFAFPEAREVAASCR	TMEM132B	161	Q14DG7
ICDRTATPLDAFRMT	GFOD1	91	Q9NXC2
MTSTIGFRVFSCLDD	NIN	286	Q8N4C6
ETSRNMLEPTITCFD	RGS4	136	P49798
FRIPFFMSQDCESLI	SIK1B	241	A0A0B4J2F2
FRIPFFMSQDCESLI	SIK1	241	P57059
CTLFIREEASPVMDA	PKHD1	1476	P08F94
SLCDVLSMDFPFEVD	SNUPN	241	O95149
FMPSDRSTERCETVL	SKI	91	P12755
FVDMFSVLCESAPRE	CIB2	91	O75838
EFLAFESVLCAPDSM	SLC25A12	76	O75746
ESVLCAPDSMFIVAF	SLC25A12	81	O75746
MCTVEEPNEEFTSRH	CLOCK	266	O15516
MEEVTTCSFNSPLFR	NEU3	1	Q9UQ49
EMVDESPAMCSSFTR	ZNF714	41	Q96N38
MDCVIFEEVAVNFTP	ZNF77	1	Q15935
IMPRDDIFVYEVCST	USP4	556	Q13107
FREDMPSILADVFCI	THOC2	76	Q8NI27
MTRFSEEACAVLTSP	VWF	576	P04275
CFISRHSIPSEMEFD	POLR2G	106	P62487
TEEFLMECGRFITPA	RPAP2	71	Q8IXW5
VDLITTGDFMSRFCS	GTF2B	206	Q00403
ACVSPSDRDFMETLN	KIF21A	346	Q7Z4S6
PMEHCTTRFFETCDL	SPARC	261	P09486
EDLAMFRSIPNCTVF	TKTL2	436	Q9H0I9
DEAVDVTPVMTCVFV	SPPL2B	216	Q8TCT7
FTCLFMSPVEDQLFR	ZNF654	236	Q8IZM8
TCDTDFLRPSDTVMQ	ST7L	196	Q8TDW4
RSADEPMTTFVLCNE	TCEA3	326	O75764
MASISEPVTFREFCP	TECPR2	1	O15040
FSLSDVSMLCSDIPD	PLCH1	1151	Q4KWH8
DTMELFIETLTGTCF	ZFAND4	26	Q86XD8
RPRYVFMEFCVEDST	PTGES3L	56	E9PB15
EVAFSSAEMLVDCVP	SMTN	861	P53814
LSFPEIMAVSSSREC	MYO7A	1511	Q13402