Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	MYT1L ZNF765 ZNF274 ZNF560 TRPS1 CHD2 ZNF224 ZFP69 ZNF441 ZNF829 ZNF440 ZNF404 ZNF512B ZNF7 ZNF514 ZBTB49 ZNF600 ZNF28 ZNF878 ZNF684 ZNF436 ZNF846 ZNF735 ZNF558 ZNF69 ZNF525 SUZ12 ZNF468 ZNF763 ZNF679 ZNF614 ZNF730 ZNF669 ZNF44	5.68e-11	1459	132	34	GO:0000977
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	MYT1L ZNF765 ZNF274 ZNF560 TRPS1 ZNF224 ZFP69 ZNF441 ZNF829 ZNF440 ZNF404 ZNF512B ZNF7 ZNF514 ZBTB49 ZNF600 ZNF28 ZNF878 ZNF684 ZNF436 ZNF846 ZNF735 ZNF558 ZNF69 ZNF525 ZNF468 ZNF679 ZNF614 ZNF730 ZNF669 ZNF44	2.08e-09	1412	132	31	GO:0000981
GeneOntologyBiologicalProcess	vitamin D3 metabolic process	CYP3A4 FGFR1 FGFR4	1.95e-05	9	129	3	GO:0070640
GeneOntologyBiologicalProcess	positive regulation of RIG-I signaling pathway	PUM2 PUM1 ZC3HAV1	3.80e-05	11	129	3	GO:1900246
Domain	ZnF_C2H2	RAG1 ZNF765 ZNF274 ZNF560 TRPS1 ZNF200 ZNF224 DPF2 ZFP69 ZNF441 ZNF829 ZNF440 ZNF404 ZNF512B ZNF7 ZNF514 ZBTB49 ZNF600 ZNF28 ZNF878 ZNF684 DPF3 ZNF436 ZNF846 ZNF735 ZNF558 ZNF69 ZNF525 SUZ12 USP39 ZNF468 ZNF763 ZNF679 ZNF614 ZNF730 ZNF669 ZNF44	7.55e-21	808	128	37	SM00355
Domain	Znf_C2H2-like	RAG1 ZNF765 ZNF274 ZNF560 TRPS1 ZNF200 ZNF224 DPF2 ZFP69 ZNF441 ZNF829 ZNF440 ZNF404 ZNF512B ZNF7 ZNF514 ZBTB49 ZNF600 ZNF28 ZNF878 ZNF684 DPF3 ZNF436 ZNF846 ZNF735 ZNF558 ZNF69 SUZ12 USP39 ZNF468 ZNF763 ZNF679 ZNF614 ZNF730 ZNF669 ZNF44	4.30e-20	796	128	36	IPR015880
Domain	KRAB	ZNF765 ZNF274 ZNF560 ZNF224 ZFP69 ZNF441 ZNF829 ZNF440 ZNF404 ZNF7 ZNF514 ZNF28 ZNF878 ZNF684 ZNF436 ZNF846 ZNF735 ZNF558 ZNF69 ZNF468 ZNF763 ZNF679 ZNF614 ZNF730 ZNF669 ZNF44	1.52e-19	358	128	26	PS50805
Domain	KRAB	ZNF765 ZNF274 ZNF560 ZNF224 ZFP69 ZNF441 ZNF829 ZNF440 ZNF404 ZNF7 ZNF514 ZNF28 ZNF878 ZNF684 ZNF436 ZNF846 ZNF735 ZNF558 ZNF69 ZNF468 ZNF763 ZNF679 ZNF614 ZNF730 ZNF669 ZNF44	1.52e-19	358	128	26	PF01352
Domain	ZINC_FINGER_C2H2_2	ZNF765 ZNF274 ZNF560 TRPS1 ZNF200 ZNF224 DPF2 ZFP69 ZNF441 ZNF829 ZNF440 ZNF404 ZNF512B ZNF7 ZNF514 ZBTB49 ZNF600 ZNF28 ZNF878 ZNF684 DPF3 ZNF436 ZNF846 ZNF735 ZNF558 ZNF69 ZNF525 SUZ12 ZNF468 ZNF763 ZNF679 ZNF614 ZNF730 ZNF669 ZNF44	1.67e-19	775	128	35	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF765 ZNF274 ZNF560 TRPS1 ZNF200 ZNF224 DPF2 ZFP69 ZNF441 ZNF829 ZNF440 ZNF404 ZNF512B ZNF7 ZNF514 ZBTB49 ZNF600 ZNF28 ZNF878 ZNF684 DPF3 ZNF436 ZNF846 ZNF735 ZNF558 ZNF69 ZNF525 SUZ12 ZNF468 ZNF763 ZNF679 ZNF614 ZNF730 ZNF669 ZNF44	1.81e-19	777	128	35	PS00028
Domain	KRAB	ZNF765 ZNF274 ZNF560 ZNF224 ZFP69 ZNF441 ZNF829 ZNF440 ZNF404 ZNF7 ZNF514 ZNF28 ZNF878 ZNF684 ZNF436 ZNF846 ZNF735 ZNF558 ZNF69 ZNF468 ZNF763 ZNF679 ZNF614 ZNF730 ZNF669 ZNF44	3.23e-19	369	128	26	SM00349
Domain	KRAB	ZNF765 ZNF274 ZNF560 ZNF224 ZFP69 ZNF441 ZNF829 ZNF440 ZNF404 ZNF7 ZNF514 ZNF28 ZNF878 ZNF684 ZNF436 ZNF846 ZNF735 ZNF558 ZNF69 ZNF468 ZNF763 ZNF679 ZNF614 ZNF730 ZNF669 ZNF44	3.46e-19	370	128	26	IPR001909
Domain	Znf_C2H2	ZNF765 ZNF274 ZNF560 TRPS1 ZNF200 ZNF224 DPF2 ZFP69 ZNF441 ZNF829 ZNF440 ZNF404 ZNF512B ZNF7 ZNF514 ZBTB49 ZNF600 ZNF28 ZNF878 ZNF684 DPF3 ZNF436 ZNF846 ZNF735 ZNF558 ZNF69 ZNF525 USP39 ZNF468 ZNF763 ZNF679 ZNF614 ZNF730 ZNF669 ZNF44	5.59e-19	805	128	35	IPR007087
Domain	-	RAG1 ZNF765 ZNF274 ZNF560 ZNF200 ZNF224 DPF2 ZFP69 ZNF441 ZNF829 ZNF440 ZNF404 ZNF7 ZNF514 ZBTB49 ZNF600 ZNF28 ZNF878 ZNF684 DPF3 ZNF436 ZNF846 ZNF735 ZNF558 ZNF69 ZNF468 ZNF763 ZNF679 ZNF614 ZNF730 ZNF669 ZNF44	2.34e-18	679	128	32	3.30.160.60
Domain	zf-C2H2	ZNF765 ZNF274 ZNF560 TRPS1 ZNF200 ZNF224 DPF2 ZFP69 ZNF441 ZNF829 ZNF440 ZNF404 ZNF7 ZNF514 ZBTB49 ZNF600 ZNF28 ZNF878 ZNF684 ZNF436 ZNF846 ZNF735 ZNF558 ZNF69 ZNF525 ZNF468 ZNF763 ZNF679 ZNF614 ZNF730 ZNF669 ZNF44	4.24e-18	693	128	32	PF00096
Domain	Znf_C2H2/integrase_DNA-bd	RAG1 ZNF765 ZNF274 ZNF560 ZNF200 ZNF224 DPF2 ZFP69 ZNF441 ZNF829 ZNF440 ZNF404 ZNF7 ZNF514 ZBTB49 ZNF600 ZNF28 ZNF878 ZNF684 DPF3 ZNF436 ZNF846 ZNF735 ZNF558 ZNF69 ZNF468 ZNF763 ZNF679 ZNF614 ZNF730 ZNF669 ZNF44	4.42e-18	694	128	32	IPR013087
Domain	zf-C2H2_6	ZNF765 ZNF560 ZNF200 ZNF224 ZNF440 ZNF404 ZNF514 ZBTB49 ZNF600 ZNF878 ZNF684 ZNF846 ZNF735 ZNF558 ZNF69 ZNF468 ZNF763 ZNF730 ZNF669 ZNF44	4.14e-14	314	128	20	PF13912
Domain	Pumilio_RNA-bd	PUM2 PUM1	4.66e-05	2	128	2	IPR033712
Domain	PUF	PUM2 PUM1	1.39e-04	3	128	2	PF00806
Domain	PUM_HD	PUM2 PUM1	1.39e-04	3	128	2	PS50303
Domain	Requiem/DPF_N_dom	DPF2 DPF3	1.39e-04	3	128	2	IPR025750
Domain	PUM-HD	PUM2 PUM1	1.39e-04	3	128	2	IPR033133
Domain	Requiem_N	DPF2 DPF3	1.39e-04	3	128	2	PF14051
Domain	Nebulin	NRAP NEB	2.77e-04	4	128	2	PF00880
Domain	NEBULIN	NRAP NEB	2.77e-04	4	128	2	PS51216
Domain	PUM	PUM2 PUM1	2.77e-04	4	128	2	PS50302
Domain	NEBU	NRAP NEB	2.77e-04	4	128	2	SM00227
Domain	Pumilio_RNA-bd_rpt	PUM2 PUM1	2.77e-04	4	128	2	IPR001313
Domain	Nebulin	NRAP NEB	2.77e-04	4	128	2	IPR013998
Domain	FGF_rcpt_fam	FGFR1 FGFR4	2.77e-04	4	128	2	IPR016248
Domain	Nebulin_repeat	NRAP NEB	2.77e-04	4	128	2	IPR000900
Domain	Pumilio	PUM2 PUM1	2.77e-04	4	128	2	SM00025
Domain	Flavin_mOase	FMO1 FMO2	4.60e-04	5	128	2	IPR000960
Domain	DiMe-aniline_mOase	FMO1 FMO2	4.60e-04	5	128	2	IPR012143
Domain	FMO-like	FMO1 FMO2	4.60e-04	5	128	2	PF00743
Domain	Flavin_mOase-like	FMO1 FMO2	4.60e-04	5	128	2	IPR020946
Domain	-	DMGDH FMO1 FMO2 RNLS	5.87e-04	56	128	4	3.50.50.60
Domain	FAD/NAD-binding_dom	DMGDH FMO1 FMO2 RNLS	6.28e-04	57	128	4	IPR023753
Pubmed	Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.	ZNF274 ZNF441 ZNF440 ZNF7 ZNF878 ZNF684 ZNF558 ZNF468 ZNF614 ZNF669 ZNF44	1.22e-10	181	133	11	37372979
Pubmed	Characterization and mapping of human genes encoding zinc finger proteins.	ZNF7 ZNF436 ZNF763 ZNF44	1.42e-06	22	133	4	1946370
Pubmed	Multiple genes encoding zinc finger domains are expressed in human T cells.	ZNF224 ZNF7 ZNF28 ZNF44	5.94e-06	31	133	4	2288909
Pubmed	Cloning and comparative sequence analysis of PUM1 and PUM2 genes, human members of the Pumilio family of RNA-binding proteins.	PUM2 PUM1	1.45e-05	2	133	2	12459267
Pubmed	Identification of diverse target RNAs that are functionally regulated by human Pumilio proteins.	PUM2 PUM1	1.45e-05	2	133	2	29165587
Pubmed	PUMILIO-mediated translational control of somatic cell cycle program promotes folliculogenesis and contributes to ovarian cancer progression.	PUM2 PUM1	1.45e-05	2	133	2	35507203
Pubmed	Bespoke RNA recognition by Pumilios.	PUM2 PUM1	1.45e-05	2	133	2	26517885
Pubmed	Mouse Pum1 and Pum2 genes, members of the Pumilio family of RNA-binding proteins, show differential expression in fetal and adult hematopoietic stem cells and progenitors.	PUM2 PUM1	1.45e-05	2	133	2	12667987
Pubmed	IKKα is required for the homeostasis of regulatory T cells and for the expansion of both regulatory and effector CD4 T cells.	RAG1 CHUK	1.45e-05	2	133	2	25376833
Pubmed	A Quantitative and Predictive Model for RNA Binding by Human Pumilio Proteins.	PUM2 PUM1	1.45e-05	2	133	2	31078383
Pubmed	Myosin-7b Promotes Distal Tip Localization of the Intermicrovillar Adhesion Complex.	MYO7B MYH7B	1.45e-05	2	133	2	27666969
Pubmed	Role of FGF Receptors and Their Pathways in Adrenocortical Tumors and Possible Therapeutic Implications.	FGFR1 FGFR4	1.45e-05	2	133	2	34956100
Pubmed	Principles of mRNA control by human PUM proteins elucidated from multimodal experiments and integrative data analysis.	PUM2 PUM1	1.45e-05	2	133	2	32753408
Pubmed	Effects of PUMILIO1 and PUMILIO2 knockdown on cardiomyogenic differentiation of human embryonic stem cells culture.	PUM2 PUM1	1.45e-05	2	133	2	32437472
Pubmed	Ubiquitination of fibroblast growth factor receptor 1 is required for its intracellular sorting but not for its endocytosis.	FGFR1 FGFR4	1.45e-05	2	133	2	18480409
Pubmed	Cerd4, third member of the d4 gene family: expression and organization of genomic locus.	DPF2 DPF3	1.45e-05	2	133	2	11845289
Pubmed	Characterization of RNP Networks of PUM1 and PUM2 Post-Transcriptional Regulators in TCam-2 Cells, a Human Male Germ Cell Model.	PUM2 PUM1	1.45e-05	2	133	2	32316190
Pubmed	Genome-wide comparison of human keratinocyte and squamous cell carcinoma responses to UVB irradiation: implications for skin and epithelial cancer.	PUM2 PUM1	1.45e-05	2	133	2	12771951
Pubmed	Alternate modes of cognate RNA recognition by human PUMILIO proteins.	PUM2 PUM1	1.45e-05	2	133	2	21397187
Pubmed	INO80 requires a polycomb subunit to regulate the establishment of poised chromatin in murine spermatocytes.	INO80 SUZ12	1.45e-05	2	133	2	35006254
Pubmed	Targeting fibroblast growth factor receptor signaling inhibits prostate cancer progression.	FGFR1 FGFR4	1.45e-05	2	133	2	22573348
Pubmed	PUMILIO proteins promote colorectal cancer growth via suppressing p21.	PUM2 PUM1	1.45e-05	2	133	2	35338151
Pubmed	Comparative analysis of mRNA targets for human PUF-family proteins suggests extensive interaction with the miRNA regulatory system.	PUM2 PUM1	1.45e-05	2	133	2	18776931
Pubmed	Human flavin-containing monooxygenase form 2 S-oxygenation: sulfenic acid formation from thioureas and oxidation of glutathione.	FMO1 FMO2	1.45e-05	2	133	2	15144220
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	MYT1L AKAP6 GAD2 RPL27A VWF MAT2A CNTNAP1 TRPS1 VPS26C TSG101 ZNF224 CHUK ZNF512B ZNF7 ZNF558 SOS2	3.40e-05	1285	133	16	35914814
Pubmed	Different clinical significance of FGFR1-4 expression between diffuse-type and intestinal-type gastric cancer.	FGFR1 FGFR4	4.34e-05	3	133	2	28056982
Pubmed	Regulation of muscle development by DPF3, a novel histone acetylation and methylation reader of the BAF chromatin remodeling complex.	DPF2 DPF3	4.34e-05	3	133	2	18765789
Pubmed	The d4 gene family in the human genome.	DPF2 DPF3	4.34e-05	3	133	2	8812431
Pubmed	Antagonistic and cooperative AGO2-PUM interactions in regulating mRNAs.	PUM2 PUM1	4.34e-05	3	133	2	30333515
Pubmed	FGFR1 and FGFR4 oncogenicity depends on n-cadherin and their co-expression may predict FGFR-targeted therapy efficacy.	FGFR1 FGFR4	4.34e-05	3	133	2	32114392
Pubmed	Development of covalent inhibitors that can overcome resistance to first-generation FGFR kinase inhibitors.	FGFR1 FGFR4	4.34e-05	3	133	2	25349422
Pubmed	Circulating small extracellular vesicles increase after an acute bout of moderate-intensity exercise in pregnant compared to non-pregnant women.	CANX TSG101	4.34e-05	3	133	2	34135428
Pubmed	A novel function of human Pumilio proteins in cytoplasmic sensing of viral infection.	PUM2 PUM1	4.34e-05	3	133	2	25340845
Pubmed	An activated lck transgene promotes thymocyte development in RAG-1 mutant mice.	RAG1 CILK1	4.34e-05	3	133	2	7889413
Pubmed	Noncoding RNA NORAD Regulates Genomic Stability by Sequestering PUMILIO Proteins.	PUM2 PUM1	4.34e-05	3	133	2	26724866
Pubmed	Polycomb repressive complex 2 component Suz12 is required for hematopoietic stem cell function and lymphopoiesis.	RAG1 SUZ12	4.34e-05	3	133	2	26036803
Pubmed	Fibroblast growth factor receptor 4 is a high affinity receptor for both acidic and basic fibroblast growth factor but not for keratinocyte growth factor.	FGFR1 FGFR4	4.34e-05	3	133	2	7680645
Pubmed	Nicotine-N'-Oxidation by Flavin Monooxygenase Enzymes.	FMO1 FMO2	4.34e-05	3	133	2	30381441
Pubmed	Deletion of the mouse Fmo1 gene results in enhanced pharmacological behavioural responses to imipramine.	FMO1 FMO2	4.34e-05	3	133	2	19262426
Pubmed	Human Pumilio proteins directly bind the CCR4-NOT deadenylase complex to regulate the transcriptome.	PUM2 PUM1	4.34e-05	3	133	2	33397688
Pubmed	NORAD: Defender of the Genome.	PUM2 PUM1	4.34e-05	3	133	2	27157388
Pubmed	The phenotype of a flavin-containing monooyxgenase knockout mouse implicates the drug-metabolizing enzyme FMO1 as a novel regulator of energy balance.	FMO1 FMO2	4.34e-05	3	133	2	24792439
Pubmed	PUMILIO/FOXP1 signaling drives expansion of hematopoietic stem/progenitor and leukemia cells.	PUM2 PUM1	4.34e-05	3	133	2	28232582
Pubmed	Characterization of the receptor for keratinocyte growth factor. Evidence for multiple fibroblast growth factor receptors.	FGFR1 FGFR4	4.34e-05	3	133	2	2165484
Pubmed	COP9 signalosome component CSN-5 stabilizes PUF proteins FBF-1 and FBF-2 in Caenorhabditis elegans germline stem and progenitor cells.	PUM2 PUM1	4.34e-05	3	133	2	38427913
Pubmed	Specificity for fibroblast growth factors determined by heparan sulfate in a binary complex with the receptor kinase.	FGFR1 FGFR4	4.34e-05	3	133	2	10336501
Pubmed	Activation of the transcription factor c-Maf in T cells is dependent on the CARMA1-IKKβ signaling cascade.	CHUK CARD11	4.34e-05	3	133	2	24345681
Pubmed	Pumilio facilitates miRNA regulation of the E2F3 oncogene.	PUM2 PUM1	4.34e-05	3	133	2	22345517
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	MYT1L AKAP6 B3GNT5 CHD2 CEP192 INO80 CHST8 TAOK3 ZNF600 OSBPL11 BOD1L1 PUM1 BTG4 TP53BP1	7.37e-05	1084	133	14	11544199
Pubmed	The protein interaction landscape of the human CMGC kinase group.	LCA5 TRPS1 LARP1 CILK1 CHD2 NEB RBM23 CHUK ZNF514 FGFR1 USP39	7.81e-05	695	133	11	23602568
Pubmed	Clustering of C2-H2 zinc finger motif sequences within telomeric and fragile site regions of human chromosomes.	ZNF436 ZNF763 ZNF44	7.98e-05	22	133	3	1505991
Pubmed	IkappaB kinase alpha kinase activity is required for self-renewal of ErbB2/Her2-transformed mammary tumor-initiating cells.	RAG1 CHUK	8.67e-05	4	133	2	17890319
Pubmed	BetaKlotho is required for metabolic activity of fibroblast growth factor 21.	FGFR1 FGFR4	8.67e-05	4	133	2	17452648
Pubmed	Differential expression of the fibroblast growth factor receptor (FGFR) multigene family in normal human adult tissues.	FGFR1 FGFR4	8.67e-05	4	133	2	9212826
Pubmed	Fibroblast growth factor 21 ameliorates cholestatic liver injury via a hepatic FGFR4-JNK pathway.	FGFR1 FGFR4	8.67e-05	4	133	2	37696161
Pubmed	Human lymphoma mutations reveal CARD11 as the switch between self-antigen-induced B cell death or proliferation and autoantibody production.	RAG1 CARD11	8.67e-05	4	133	2	23027925
Pubmed	FGFR1-4 RNA-Based Gene Alteration and Expression Analysis in Squamous Non-Small Cell Lung Cancer.	FGFR1 FGFR4	8.67e-05	4	133	2	36142417
Pubmed	Immunohistochemical detection of fibroblast growth factor receptors in normal endocrine cells and related tumors of the digestive system.	FGFR1 FGFR4	8.67e-05	4	133	2	11759058
Pubmed	Differential expression of fibroblast growth factor receptors in the developing murine choroid plexus.	FGFR1 FGFR4	8.67e-05	4	133	2	12644244
Pubmed	FGFR-4, a novel acidic fibroblast growth factor receptor with a distinct expression pattern.	FGFR1 FGFR4	8.67e-05	4	133	2	1709094
Pubmed	Mammalian Pum1 and Pum2 Control Body Size via Translational Regulation of the Cell Cycle Inhibitor Cdkn1b.	PUM2 PUM1	8.67e-05	4	133	2	30811992
Pubmed	Responsiveness of developing dental tissues to fibroblast growth factors: expression of splicing alternatives of FGFR1, -2, -3, and of FGFR4; and stimulation of cell proliferation by FGF-2, -4, -8, and -9.	FGFR1 FGFR4	8.67e-05	4	133	2	9664689
Pubmed	Compensatory IKKalpha activation of classical NF-kappaB signaling during IKKbeta inhibition identified by an RNA interference sensitization screen.	CHUK CARD11	8.67e-05	4	133	2	19104039
Pubmed	In vivo CRISPR screening reveals nutrient signaling processes underpinning CD8+ T cell fate decisions.	RAG1 POFUT1	8.67e-05	4	133	2	33636132
Pubmed	Regulation of renal phosphate transport by FGF23 is mediated by FGFR1 and FGFR4.	FGFR1 FGFR4	8.67e-05	4	133	2	24259513
Pubmed	ORP10, a cholesterol binding protein associated with microtubules, regulates apolipoprotein B-100 secretion.	OSBPL11 OSBPL10	8.67e-05	4	133	2	22906437
Pubmed	Expression of fibroblast growth factor receptor family members is associated with prognosis in early stage cervical cancer patients.	FGFR1 FGFR4	8.67e-05	4	133	2	27154171
Pubmed	Immunolocalization of fibroblast growth factor receptors in normal and wounded human skin.	FGFR1 FGFR4	8.67e-05	4	133	2	12373339
Pubmed	Target RNA motif and target mRNAs of the Quaking STAR protein.	PUM2 PUM1	8.67e-05	4	133	2	16041388
Pubmed	The FGF system has a key role in regulating vascular integrity.	FGFR1 FGFR4	8.67e-05	4	133	2	18776942
Pubmed	Quantitative analysis of FMO gene mRNA levels in human tissues.	FMO1 FMO2	8.67e-05	4	133	2	16183778
Pubmed	The molecular biology of the flavin-containing monooxygenases of man.	FMO1 FMO2	8.67e-05	4	133	2	7720101
Pubmed	RNAi-based conditional gene knockdown in mice using a U6 promoter driven vector.	FGFR1 FGFR4	8.67e-05	4	133	2	17304337
Pubmed	FGF/FGFR2 signaling regulates the generation and correct positioning of Bergmann glia cells in the developing mouse cerebellum.	GAD2 FGFR1 FGFR4	1.18e-04	25	133	3	24983448
Pubmed	The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.	RPL27A MAT2A CANX LARP1 CILK1 CHD2 CEP192 TRAP1 DPF3 ZNF735 FGFR1 FGFR4 ZNF468 ZC3HAV1	1.41e-04	1153	133	14	29845934
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	CANX TRPS1 TMEM63B LARP1 TSG101 CEP192 DPF2 FAM83B NBAS TRAP1 SYTL4 POC1B USP39 TP53BP1	1.43e-04	1155	133	14	20360068
Pubmed	Conditional knockdown of Fgfr2 in mice using Cre-LoxP induced RNA interference.	FGFR1 FGFR4	1.44e-04	5	133	2	15987787
Pubmed	The mammalian flavin-containing monooxygenases: molecular characterization and regulation of expression.	FMO1 FMO2	1.44e-04	5	133	2	8128486
Pubmed	The expression profiles of fibroblast growth factor 9 and its receptors in developing mice testes.	FGFR1 FGFR4	1.44e-04	5	133	2	27078042
Pubmed	Different intracellular trafficking of FGF1 endocytosed by the four homologous FGF receptors.	FGFR1 FGFR4	1.44e-04	5	133	2	16091423
Pubmed	FGF-dependent regulation of VEGF receptor 2 expression in mice.	FGFR1 FGFR4	1.44e-04	5	133	2	21633168
Pubmed	FGF23 induced left ventricular hypertrophy mediated by FGFR4 signaling in the myocardium is attenuated by soluble Klotho in mice.	FGFR1 FGFR4	1.44e-04	5	133	2	31758962
Pubmed	Differential effects of heparin saccharides on the formation of specific fibroblast growth factor (FGF) and FGF receptor complexes.	FGFR1 FGFR4	1.44e-04	5	133	2	11714710
Pubmed	PUM1 and PUM2 exhibit different modes of regulation for SIAH1 that involve cooperativity with NANOS paralogues.	PUM2 PUM1	1.44e-04	5	133	2	30269240
Pubmed	Distinct association of genetic variations of vascular endothelial growth factor, transforming growth factor-beta, and fibroblast growth factor receptors with atopy and airway hyperresponsiveness.	FGFR1 FGFR4	1.44e-04	5	133	2	18315732
Pubmed	Efficient regulation of branching morphogenesis via fibroblast growth factor receptor 2c in early-stage embryonic mouse salivary glands.	FGFR1 FGFR4	1.44e-04	5	133	2	27206683
Pubmed	Flavin-Containing Monooxygenase 1 Catalyzes the Production of Taurine from Hypotaurine.	FMO1 FMO2	1.44e-04	5	133	2	32156684
Pubmed	Langerhans cells are an essential cellular intermediary in chronic dermatitis.	RAG1 SUZ12	1.44e-04	5	133	2	35675765
Pubmed	Phosphorylation of the CARMA1 linker controls NF-kappaB activation.	CHUK CARD11	1.44e-04	5	133	2	16356855
Pubmed	An Important Role of Pumilio 1 in Regulating the Development of the Mammalian Female Germline.	PUM2 PUM1	1.44e-04	5	133	2	27170441
Pubmed	Interaction of torsinA with its major binding partners is impaired by the dystonia-associated DeltaGAG deletion.	CANX TOR3A	1.44e-04	5	133	2	19651773
Pubmed	Expression of fibroblast growth factor receptors in peri-implantation mouse embryos.	FGFR1 FGFR4	1.44e-04	5	133	2	9771645
Pubmed	Persistent fibroblast growth factor 23 signalling in the parathyroid glands for secondary hyperparathyroidism in mice with chronic kidney disease.	FGFR1 FGFR4	1.44e-04	5	133	2	28094278
Pubmed	Disruption of the basal body protein POC1B results in autosomal-recessive cone-rod dystrophy.	LCA5 POC1B	1.44e-04	5	133	2	25018096
Pubmed	A nomenclature for the mammalian flavin-containing monooxygenase gene family based on amino acid sequence identities.	FMO1 FMO2	1.44e-04	5	133	2	8311461
Pubmed	Differential specificity of endocrine FGF19 and FGF21 to FGFR1 and FGFR4 in complex with KLB.	FGFR1 FGFR4	1.44e-04	5	133	2	22442730
Pubmed	53BP1 facilitates long-range DNA end-joining during V(D)J recombination.	RAG1 TP53BP1	1.44e-04	5	133	2	18931658
Pubmed	Overlapping expression and redundant activation of mesenchymal fibroblast growth factor (FGF) receptors by alternatively spliced FGF-8 ligands.	FGFR1 FGFR4	1.44e-04	5	133	2	9013630
Pubmed	The mouse Fgfrl1 gene coding for a novel FGF receptor-like protein.	FGFR1 FGFR4	1.44e-04	5	133	2	11566361
Pubmed	High-throughput analyses of hnRNP H1 dissects its multi-functional aspect.	RPL27A CANX LARP1 PUM2 CHD2 ZNF829 ZNF512B RIMKLB DNAH17 SCUBE3 TOR3A DMPK PUM1	1.55e-04	1021	133	13	26760575
Cytoband	19p13.2	ZNF560 ZNF441 ZNF440 ZNF878 ZNF846 ZNF558 ZNF69 ZNF763 ZNF44	2.60e-08	229	133	9	19p13.2
Cytoband	19q13.41	ZNF600 ZNF28 ZNF468 ZNF614	8.13e-05	78	133	4	19q13.41
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	ZNF765 ZNF274 ZNF224 ZNF829 ZNF404 CHST8 ZNF600 ZNF28 ZNF525 ZNF468 DMPK ZNF614	1.91e-04	1192	133	12	chr19q13
Cytoband	Ensembl 112 genes in cytogenetic band chr19p13	ZNF560 ZNF441 ZNF440 ZNF878 ZNF846 ZNF558 ZNF69 ZNF763 ZNF44	5.51e-04	797	133	9	chr19p13
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF765 ZNF274 ZNF560 TRPS1 ZNF200 ZNF224 ZFP69 ZNF441 ZNF829 ZNF440 ZNF404 ZNF7 ZNF514 ZBTB49 ZNF600 ZNF28 ZNF878 ZNF684 ZNF436 ZNF846 ZNF735 ZNF558 ZNF69 ZNF525 SUZ12 ZNF468 ZNF763 ZNF679 ZNF614 ZNF730 ZNF669 ZNF44	2.88e-21	718	97	32	28
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	ARHGAP23 OSBPL11 OSBPL10 FGD5 PHLDB2 SOS2	8.50e-04	206	97	6	682
GeneFamily	Oxysterol binding proteins\|Pleckstrin homology domain containing	OSBPL11 OSBPL10	1.82e-03	12	97	2	670
Disease	fibrolamellar carcinoma (is_marker_for)	CA12 FGFR1	1.90e-05	2	129	2	DOID:5015 (is_marker_for)
Disease	insulin sensitivity measurement, glucose homeostasis measurement	MYT1L LCA5 DOCK5 TAOK3	3.77e-05	43	129	4	EFO_0004471, EFO_0006896
Disease	Ataxia	HK1 CP PUM1	1.75e-04	25	129	3	C0004134
Disease	bone disease (implicated_via_orthology)	FGFR1 FGFR4	1.88e-04	5	129	2	DOID:0080001 (implicated_via_orthology)
Disease	FEV/FEC ratio	AKAP6 PDE1C RNLS TRPS1 ANO1 NEB FAM83B FCGR3A SYTL4 SCUBE3 FGFR1 POFUT1 FGFR4 SUZ12 PHLDB2	3.15e-04	1228	129	15	EFO_0004713
Disease	mesangial proliferative glomerulonephritis (biomarker_via_orthology)	VWF FGFR1	5.22e-04	8	129	2	DOID:4783 (biomarker_via_orthology)
Disease	4-vinylphenol sulfate measurement	SGK3 SOS2	8.34e-04	10	129	2	EFO_0021149
Disease	vascular endothelial function measurement	ZNF765 ZNF28 ZNF468 PHLDB2	9.52e-04	99	129	4	EFO_0803369
Disease	suntan	MYH7B TRPS1 MMP24 POFUT1	1.10e-03	103	129	4	EFO_0004279
Disease	Methionine sulfoxide measurement	FMO1 FMO2	1.22e-03	12	129	2	EFO_0021650
Disease	birth weight, parental genotype effect measurement	CYP3A4 MYH7B INO80 ZNF512B FGD5	1.59e-03	192	129	5	EFO_0004344, EFO_0005939
Disease	cleft lip	AKAP6 CA12 KCNK9 ZNF404 LZTS1 FGFR4	1.60e-03	284	129	6	EFO_0003959
Disease	actinic keratosis	TRPS1 MMP24	1.67e-03	14	129	2	EFO_0002496
Disease	Small cell carcinoma of lung	TAOK3 FGFR1 DMPK	1.72e-03	54	129	3	C0149925
Disease	colon cancer (is_marker_for)	ATG101 CHUK FGFR4	2.22e-03	59	129	3	DOID:219 (is_marker_for)
Disease	protein C measurement	MYO7B MYH7B	2.47e-03	17	129	2	EFO_0004633
Disease	Global developmental delay	HK1 NBAS SUZ12 PUM1	2.81e-03	133	129	4	C0557874
Disease	ascending aortic diameter	ANO1 KCNK9 FGD5 HYDIN	3.38e-03	140	129	4	EFO_0021787
Disease	Intellectual Disability	MYT1L AKAP6 HK1 SRD5A3 DPF2 SUZ12 PUM1	3.59e-03	447	129	7	C3714756
Disease	fat intake measurement	NRAP CHN2	4.14e-03	22	129	2	EFO_0010809
Disease	age at onset, Myopia	AKAP6 RNLS SGK3 HYDIN	4.32e-03	150	129	4	EFO_0004847, HP_0000545
Disease	creatinine measurement	DMGDH RNLS MYH7B CHD2 INO80 NEB FAM83B MMP24 DPF3 FGFR4 SOS2	4.35e-03	995	129	11	EFO_0004518

Protein segments in the cluster

Peptide	Gene	Start	Entry
YKGSYHTNEPKAAHE	CNTNAP1	1311	P78357
GVHHIDYYKKTSNGR	FGFR4	636	P22455
DHFHVKGCSYVLYKP	BIVM	276	Q86UB2
RIHEYKPLKTRFYTH	C6orf163	31	Q5TEZ5
SYENGHPHVIYKKSA	ADAMTS6	181	Q9UKP5
YEGKITNYFHKTLAH	RAG1	931	P15918
LATGYRYGHSKSPHF	RBM23	131	Q86U06
PHITTLRKYTYGKHI	PUM2	1026	Q8TB72
KPYHISKFIYRHGQI	INO80	836	Q9ULG1
KRHHPQYERSHGQYK	LUZP4	181	Q9P127
KLAPHYFHSISYKIE	KCNK9	321	Q9NPC2
SSKDNIRGKHVRHYY	CP	361	P00450
KHITYSIHNYTPKVG	MMP24	166	Q9Y5R2
TLKYAIKTGHPRYFN	GAD2	166	Q05329
KENGFTQHVYHKYRR	LARP1	881	Q6PKG0
FYIKVSQKARGSHHP	LZTS1	66	Q9Y250
ESKYRQHPHSFKYTA	NRAP	1201	Q86VF7
HGGRFPVLSYYHKKN	MTMR9	181	Q96QG7
RYKNRPGLSYHYAHT	DPF3	206	Q92784
DLYKQLKHRPSDHSY	CHUK	566	O15111
LKKPIYQRTAAYGHF	MAT2A	366	P31153
NRLYKHGYIHIGSFS	KIAA1109	61	Q2LD37
PSYDKIFSHLQHVKY	CA12	181	O43570
LLYLYGTHSHGLFKK	CYP3A4	21	P08684
NEHDKYNIRSHGYKP	FAM83B	346	Q5T0W9
KRKYQAHFEVVHYAG	MYH7B	616	A7E2Y1
EPYHKKEHYLSGVNE	PLXNA4	151	Q9HCM2
LEVGYSKHKNPYHNL	PDE1C	216	Q14123
GPIFHLYHKKTLFYS	FGD5	1426	Q6ZNL6
TYDHSCPEGFVYKHK	NSG2	96	Q9Y328
FKYKTPQHRHYLSFE	DNAJC28	126	Q9NX36
YRHLANSKKYQTPPH	KDM4D	101	Q6B0I6
DQERKAGKHHYSYLS	LCA5	11	Q86VQ0
KVDYILVYHHKRPSG	ANO1	61	Q5XXA6
NFKPHARAYRYVGHK	POC1B	46	Q8TC44
FHSQSGFYYKTRIPK	NOL10	121	Q9BSC4
LYKTHPQYSRRFHKT	HK1	416	P19367
AHKGKPHYRVSYEKS	NBAS	1156	A2RRP1
TYGKIVHYKEHLSLP	DMPK	286	Q09013
PHIATLRKYTYGKHI	PUM1	1146	Q14671
HQFYKSKFVSYPKHR	SRD5A3	296	Q9H8P0
YVLYPKPHKESQRHA	IL1RL2	386	Q9HB29
HTSAGPRYQYLINHK	B3GNT5	66	Q9BYG0
GKTKSVRHAYVHKPY	BOD1L1	461	Q8NFC6
KGTGHPNSYHFKYII	B3GALT2	126	O43825
YEKTHNFKVHTFRGP	CHN2	211	P52757
FLDSKHPGHYAVYNL	GAK	441	O14976
HRSTGKFHYKKEGTY	ATG101	31	Q9BSB4
THYYHFKLINKGRRI	HYDIN	926	Q4G0P3
HYSDYFPLKLLKTHD	AWAT2	81	Q6E213
HFNPVLETYIYKHFS	DOCK5	711	Q9H7D0
YHPKFRLILHTKYFN	DNAH17	3521	Q9UFH2
RLILHTKYFNPHYKP	DNAH17	3526	Q9UFH2
HYRSFHTDKLGEYKQ	CHD2	1761	O14647
RDIHHIDYYKKTTNG	FGFR1	646	P11362
GIHYGQVSKKHIIYS	CLLU1	91	Q5K131
FKGQYFHSRQYKHPD	FMO1	166	Q01740
GHFKYLSAHNYKIEH	TMEM63B	731	Q5T3F8
HFIFRHKNPKTGIYE	CANX	201	P27824
TTYFHPGINLKKIHY	DMGDH	96	Q9UI17
PFYVKHSKYSLRAQH	CEP192	2481	Q8TEP8
FKGQYFHSRQYKHPD	FMO2	166	Q99518
KGRKYFHHNSDFYIP	FCGR3A	146	P08637
LAHPQNYFKYTEKHK	SCUBE3	956	Q8IX30
KNVKHPFLVGLHYSF	SGK3	216	Q96BR1
MKVSYRGHFLHNIYP	BVES	181	Q8NE79
PVTLHYKVNHEGYRK	CARD11	746	Q9BXL7
TFHTKPFYGGKLHRV	OSBPL11	601	Q9BXB4
HRINFDKYHPGYFGK	RPL27A	41	P46776
HKPPFTNLHVSYQKY	POFUT1	76	Q9H488
KKTLNPHYNHTFVYN	SYTL4	571	Q96C24
HPSLKEVLGYKVDYH	SOS2	111	Q07890
KYFQGRGLKSHAYIH	USP39	141	Q53GS9
HPNTIEYKGCYLKEH	TAOK3	81	Q9H2K8
KKGHHKLYRYDGQHF	SETD1B	41	Q9UPS6
PPYSKYSSRHKSHDN	PHLDB2	146	Q86SQ0
FHTKPFYGGKVHRVT	OSBPL10	626	Q9BXB5
DGKPISAYDHKYLHR	ABCB9	566	Q9NP78
TYHGSQKHPKCYRPA	BTG4	201	Q9NY30
YPTYHVKKKHTRLGR	AKAP6	681	Q13023
YTYRHPFVQEKTKHK	ADD2	381	P35612
KQHYLKHSRYLPGIS	CILK1	486	Q9UPZ9
KFEHPNSYYHPVFGK	CHST8	271	Q9H2A9
KHVDANGKIYLPYLH	TSG101	101	Q99816
YDHRHAGNKPIKYQL	ZNF525	126	Q8N782
LTYHHRLHTGEKPYK	ZNF525	286	Q8N782
YLACHRSIHTGKKPY	ZNF525	341	Q8N782
KYKLSVPGNPHYLSH	TRPS1	1116	Q9UHF7
HKRTHTGEKPYEYQE	ZNF440	246	Q8IYI8
LYKHSRFHTGEKPYQ	ZNF684	286	Q5T5D7
EKSHPSVPYHYFEKG	ST6GALNAC4	241	Q9H4F1
YIRVHEKTHTGEKPY	ZNF441	461	Q8N8Z8
ALIYHKRIHTGEKPY	ZNF735	311	P0CB33
YLTDHTRIHSGKKPY	ZNF846	296	Q147U1
HQKTHTGDRPYKCYE	ZNF436	156	Q9C0F3
HLGEKTYHYVPEFRK	YIPF1	146	Q9Y548
YHDGSHAYIGLKDRK	VWF	1321	P04275
TPHYAKKHQRFYDEL	RNLS	66	Q5VYX0
KHYLKESGAEVYFRH	RNLS	116	Q5VYX0
GHYYETLKFLVGHLK	ARHGAP23	1026	Q9P227
HSRFIFNYVYHPKGA	SUZ12	471	Q15022
YLTQHVRTHTGEKPY	ZNF558	306	Q96NG5
VLHYRFHTGEKPYKC	ZNF514	276	Q96K75
LIVHYRFHTGEKPYK	ZNF514	331	Q96K75
QHYRFHTGEKPYKCN	ZNF514	361	Q96K75
LTYHKRIHTGEKPYT	ZNF679	311	Q8IYX0
YFSVHKKIHTGERPY	ZNF274	521	Q96GC6
KRYKNRPGLSYHYAH	DPF2	216	Q92785
HEAPYLFQKYVKESH	RIMKLB	186	Q9ULI2
RIGFKQHPKYKHDYV	TP53BP1	1956	Q12888
YFSQHQRIHTGEKPY	ZNF829	226	Q3KNS6
NRHKITHTGGKPYKY	ZNF730	356	Q6ZMV8
YLISHQRTHTGEKPY	ZNF200	266	P98182
YHQTIHTGLKPYVCK	ZNF404	456	Q494X3
GKTYRSKAGHDYHVR	ZNF512B	636	Q96KM6
AHDKPRYTLHYKTDA	TRAP1	321	Q12931
LHHKLSGKQNSYYPP	UBR3	1096	Q6ZT12
FRYHERTHTGEKPYK	ZNF69	521	Q9UC07
YLAKHTIIHTGEKPY	ZNF28	341	P17035
LTYHHRLHTGQKPYK	ZNF765	481	Q7L2R6
LRNFYSKQYHKHAAG	ZBTB49	216	Q6ZSB9
LHETHENKYGKGIYF	ZC3HAV1	806	Q7Z2W4
YLIAHQRTHSGEKPY	ZNF614	301	Q8N883
YSHQRSHSGEKPYKC	ZNF224	416	Q9NZL3
FHFPHPKYVDLYKEQ	TOR3A	201	Q9H497
SYLRHKRSHTGEKPY	ZNF763	326	Q0D2J5
PSRKKGDNYYLNRTH	FARS2	136	O95363
IHKSIHTGEQPYKYE	ZNF600	431	Q6ZNG1
YLAKHTILHTGEKPY	ZNF468	341	Q5VIY5
YLRHERTHTGEKPYK	ZNF44	316	P15621
YLKTHERTHTAEKPY	ZNF44	566	P15621
SLIYHQRIHKGEKPY	ZNF7	511	P17097
YLTKHLRRHSGEKPY	ZNF560	586	Q96MR9
TKHLRRHTGDKPYEY	ZNF560	616	Q96MR9
HLRTHTGYKPYKCNA	ZNF560	646	Q96MR9
PLHLKGNKVLYETYH	VPS26C	96	O14972
RHILAHSGYKPYGEK	ZNF669	206	Q96BR6
FRYHEKTHTGEKPYE	ZNF878	326	C9JN71
RHHKYDTPTKRNTYK	ZFP69	241	Q49AA0
KTKFPAEQYYRFHEH	TSN	76	Q15631
TPQQYERSFHFKYLH	ART4	146	Q93070
HYHQELPKYLRGFHK	MYO7B	1911	Q6PIF6
YDNHTYGKRAIAPKV	MYT1L	651	Q9UL68
EFKYKEGYRKQLGHH	NEB	2791	P20929
YEKSKGHYHTIPDNL	NEB	5871	P20929