Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionendopeptidase activity

ADAMTS10 MST1 CASP12 ADAMTS3 ADAMTS1 PIGK TLL1 TLL2 USP29 ADAMTS20 KLK1 F10 USP33

4.00e-094307213GO:0004175
GeneOntologyMolecularFunctionpeptidase activity

ADAMTS10 MST1 CASP12 ADAMTS3 ADAMTS1 PIGK TLL1 TLL2 USP29 ADAMTS20 MINDY2 KLK1 F10 USP33

7.36e-086547214GO:0008233
GeneOntologyMolecularFunctionmetalloendopeptidase activity

ADAMTS10 ADAMTS3 ADAMTS1 TLL1 TLL2 ADAMTS20

4.70e-06120726GO:0004222
GeneOntologyMolecularFunctionhistone phosphatase activity

EYA2 EYA3

3.84e-053722GO:0140789
GeneOntologyMolecularFunctionhistone H2AXY142 phosphatase activity

EYA2 EYA3

3.84e-053722GO:0140793
GeneOntologyMolecularFunctionmetallopeptidase activity

ADAMTS10 ADAMTS3 ADAMTS1 TLL1 TLL2 ADAMTS20

8.45e-05200726GO:0008237
GeneOntologyMolecularFunctioncysteine-type endopeptidase activity

CASP12 PIGK USP29 USP33

2.64e-0486724GO:0004197
GeneOntologyMolecularFunctionserine-type endopeptidase activity

MST1 TLL1 TLL2 KLK1 F10

6.18e-04190725GO:0004252
GeneOntologyMolecularFunctioncysteine-type peptidase activity

CASP12 PIGK USP29 MINDY2 USP33

6.48e-04192725GO:0008234
GeneOntologyMolecularFunctionserine-type peptidase activity

MST1 TLL1 TLL2 KLK1 F10

9.09e-04207725GO:0008236
GeneOntologyMolecularFunctionserine hydrolase activity

MST1 TLL1 TLL2 KLK1 F10

1.01e-03212725GO:0017171
GeneOntologyBiologicalProcessextracellular matrix organization

ADAMTS10 ADAMTS3 ADAMTS1 ACAN TLL1 TLL2 ADAMTS20 PAPLN

4.51e-05377718GO:0030198
GeneOntologyBiologicalProcessextracellular structure organization

ADAMTS10 ADAMTS3 ADAMTS1 ACAN TLL1 TLL2 ADAMTS20 PAPLN

4.59e-05378718GO:0043062
GeneOntologyBiologicalProcessexternal encapsulating structure organization

ADAMTS10 ADAMTS3 ADAMTS1 ACAN TLL1 TLL2 ADAMTS20 PAPLN

4.68e-05379718GO:0045229
GeneOntologyBiologicalProcesscollagen fibril organization

ADAMTS3 ACAN TLL1 TLL2

1.37e-0476714GO:0030199
GeneOntologyBiologicalProcessprotein K48-linked deubiquitination

USP29 MINDY2 USP33

1.64e-0431713GO:0071108
GeneOntologyCellularComponentextracellular matrix

ADAMTS10 MST1 ADAMTS3 ADAMTS1 MUC17 GLG1 ACAN ADAMTS20 PAPLN

3.67e-04656719GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

ADAMTS10 MST1 ADAMTS3 ADAMTS1 MUC17 GLG1 ACAN ADAMTS20 PAPLN

3.75e-04658719GO:0030312
GeneOntologyCellularComponentcollagen-containing extracellular matrix

ADAMTS10 MST1 ADAMTS3 ADAMTS1 MUC17 ACAN ADAMTS20 PAPLN

4.24e-04530718GO:0062023
GeneOntologyCellularComponentGolgi lumen

FGF23 MUC17 ACAN F10

5.19e-04109714GO:0005796
GeneOntologyCellularComponenttranscription elongation factor complex

SUPT5H ELP2 ICE1

9.15e-0456713GO:0008023
DomainADAM_spacer1

ADAMTS10 ADAMTS3 ADAMTS1 ADAMTS20 PAPLN

1.90e-0823695IPR010294
DomainADAM_spacer1

ADAMTS10 ADAMTS3 ADAMTS1 ADAMTS20 PAPLN

1.90e-0823695PF05986
DomainPeptidase_M12B_ADAM-TS

ADAMTS10 ADAMTS3 ADAMTS1 ADAMTS20 PAPLN

2.39e-0824695IPR013273
DomainMetalloPept_cat_dom

ADAMTS10 ADAMTS3 ADAMTS1 TLL1 TLL2 ADAMTS20

5.32e-0781696IPR024079
Domain-

ADAMTS10 ADAMTS3 ADAMTS1 TLL1 TLL2 ADAMTS20

5.32e-07816963.40.390.10
DomainZINC_PROTEASE

ADAMTS10 ADAMTS3 ADAMTS1 TLL1 TLL2 ADAMTS20

1.64e-0698696PS00142
DomainTSP_1

ADAMTS10 ADAMTS3 ADAMTS1 ADAMTS20 PAPLN

3.54e-0663695PF00090
DomainTSP1

ADAMTS10 ADAMTS3 ADAMTS1 ADAMTS20 PAPLN

4.13e-0665695SM00209
DomainTSP1_rpt

ADAMTS10 ADAMTS3 ADAMTS1 ADAMTS20 PAPLN

4.13e-0665695IPR000884
DomainTSP1

ADAMTS10 ADAMTS3 ADAMTS1 ADAMTS20 PAPLN

4.13e-0665695PS50092
DomainPeptidase_M12B_N

ADAMTS10 ADAMTS3 ADAMTS1 ADAMTS20

1.27e-0539694IPR002870
DomainPep_M12B_propep

ADAMTS10 ADAMTS3 ADAMTS1 ADAMTS20

1.27e-0539694PF01562
DomainDISINTEGRIN_1

ADAMTS10 ADAMTS3 ADAMTS1 ADAMTS20

1.41e-0540694PS00427
DomainReprolysin

ADAMTS10 ADAMTS3 ADAMTS1 ADAMTS20

1.41e-0540694PF01421
DomainADAM_MEPRO

ADAMTS10 ADAMTS3 ADAMTS1 ADAMTS20

1.41e-0540694PS50215
DomainDISINTEGRIN_2

ADAMTS10 ADAMTS3 ADAMTS1 ADAMTS20

1.41e-0540694PS50214
DomainPeptidase_M12B

ADAMTS10 ADAMTS3 ADAMTS1 ADAMTS20

1.41e-0540694IPR001590
DomainDisintegrin_dom

ADAMTS10 ADAMTS3 ADAMTS1 ADAMTS20

1.56e-0541694IPR001762
DomainBMP_1/tolloid-like

TLL1 TLL2

4.03e-053692IPR015446
DomainPLAC

ADAMTS10 ADAMTS3 PAPLN

4.48e-0519693PS50900
DomainPLAC

ADAMTS10 ADAMTS3 PAPLN

4.48e-0519693IPR010909
DomainEYA_fam

EYA2 EYA3

8.03e-054692IPR028472
DomainEYA_dom

EYA2 EYA3

8.03e-054692IPR006545
DomainPeptidase_M12A

TLL1 TLL2

2.00e-046692IPR001506
DomainAstacin

TLL1 TLL2

2.00e-046692PF01400
DomainPLAC

ADAMTS10 PAPLN

1.19e-0314692PF08686
DomainSpectrin

SYNE1 SPTAN1

3.24e-0323692PF00435
DomainVWC

PXDNL KCP

4.78e-0328692PF00093
DomainPH_dom-like

MTMR4 NECAP2 NBEAL1 ARHGEF12 APBA3 SPRED1

4.86e-03426696IPR011993
DomainZnMc

TLL1 TLL2

5.12e-0329692SM00235
DomainPeptidase_Metallo

TLL1 TLL2

5.12e-0329692IPR006026
DomainSpectrin_repeat

SYNE1 SPTAN1

5.12e-0329692IPR002017
DomainEGF_Ca-bd_CS

TLL1 TLL2 F10

5.55e-0397693IPR018097
DomainEGF_CA

TLL1 TLL2 F10

5.88e-0399693PS01187
Domainzf-C2H2_6

ZNF600 ZNF473 ZNF611 ZNF576 ZNF808

6.08e-03314695PF13912
DomainSpectrin/alpha-actinin

SYNE1 SPTAN1

6.21e-0332692IPR018159
DomainSPEC

SYNE1 SPTAN1

6.21e-0332692SM00150
DomainEGF-type_Asp/Asn_hydroxyl_site

TLL1 TLL2 F10

7.10e-03106693IPR000152
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

ADAMTS10 ADAMTS3 ADAMTS1 MUC17 ADAMTS20

3.64e-0668495M27303
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

ADAMTS10 ADAMTS3 ADAMTS1 MUC17 ACAN ADAMTS20

9.58e-06143496M27275
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

ADAMTS10 ADAMTS3 ADAMTS1 ADAMTS20

9.69e-0639494M27417
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

ADAMTS10 ADAMTS3 ADAMTS1 ADAMTS20

9.69e-0639494MM15165
PathwayREACTOME_O_LINKED_GLYCOSYLATION

ADAMTS10 ADAMTS3 ADAMTS1 MUC17 ADAMTS20

3.67e-05109495MM15164
PathwayREACTOME_O_LINKED_GLYCOSYLATION

ADAMTS10 ADAMTS3 ADAMTS1 MUC17 ADAMTS20

4.00e-05111495M27416
PathwayREACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION

ADAMTS10 FGF23 KLHL5 RNF123 ADAMTS3 ADAMTS1 MUC17 PIGK SPTAN1 USP29 ADAMTS20 CLSPN F10 USP33

1.87e-0413894914MM15307
PathwayREACTOME_DISEASES_OF_METABOLISM

ADAMTS10 ADAMTS3 ADAMTS1 MUC17 ACAN ADAMTS20

2.16e-04250496M27554
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

TARS3 RNF123 WARS1 ZNF473 ADAMTS1 CIAO3 SUPT5H SYNE1 SPTAN1 SPRED1 EYA3 CBR3 USP33 ZNF292 ZNF662

7.09e-081285741535914814
Pubmed

O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.

ADAMTS10 ADAMTS3 ADAMTS1 ADAMTS20 PAPLN

5.84e-077574520637190
Pubmed

Insights on ADAMTS proteases and ADAMTS-like proteins from mammalian genetics.

ADAMTS10 ADAMTS1 ADAMTS20

2.01e-061274325770910
Pubmed

ADAMTS2 promotes radial migration by activating TGF-β signaling in the developing neocortex.

ADAMTS10 ADAMTS3 ADAMTS1

4.13e-061574338871984
Pubmed

USP29 controls the stability of checkpoint adaptor Claspin by deubiquitination.

USP29 CLSPN

4.47e-06274224632611
Pubmed

Follicular ADAMTS-1 and aggrecan levels in polycystic ovary syndrome.

ADAMTS1 ACAN

4.47e-06274228417352
Pubmed

Multiple bone morphogenetic protein 1-related mammalian metalloproteinases process pro-lysyl oxidase at the correct physiological site and control lysyl oxidase activation in mouse embryo fibroblast cultures.

TLL1 TLL2

4.47e-06274211313359
Pubmed

Dephosphorylation of the C-terminal tyrosyl residue of the DNA damage-related histone H2A.X is mediated by the protein phosphatase eyes absent.

EYA2 EYA3

1.34e-05374219351884
Pubmed

A human homologue of the Drosophila eyes absent gene underlies branchio-oto-renal (BOR) syndrome and identifies a novel gene family.

EYA2 EYA3

1.34e-0537429020840
Pubmed

Assignment of TLL1 and TLL2, which encode human BMP-1/Tolloid-related metalloproteases, to chromosomes 4q32-->q33 and 10q23-->q24 and assignment of murine Tll2 to chromosome 19.

TLL1 TLL2

1.34e-05374210516436
Pubmed

Eyes absent represents a class of protein tyrosine phosphatases.

EYA2 EYA3

1.34e-05374214628052
Pubmed

Structural basis for the substrate specificity of bone morphogenetic protein 1/tolloid-like metalloproteases.

TLL1 TLL2

1.34e-05374218824173
Pubmed

Genetic variants in the metzincin metallopeptidase family genes predict melanoma survival.

ADAMTS3 TLL2

2.67e-05474228796414
Pubmed

Mammalian tolloid proteinases: role in growth factor signalling.

TLL1 TLL2

2.67e-05474227391803
Pubmed

ADAMTS: a novel family of proteases with an ADAM protease domain and thrombospondin 1 repeats.

ADAMTS3 ADAMTS1

2.67e-05474210094461
Pubmed

Misexpression of the eyes absent family triggers the apoptotic program.

EYA2 EYA3

2.67e-05474211700312
Pubmed

Partially redundant functions of Adamts1 and Adamts4 in the perinatal development of the renal medulla.

ADAMTS1 ACAN

2.67e-05474221584905
Pubmed

Eyes absent: a gene family found in several metazoan phyla.

EYA2 EYA3

4.45e-0557429195991
Pubmed

Fibulin-1 acts as a cofactor for the matrix metalloprotease ADAMTS-1.

ADAMTS1 ACAN

4.45e-05574216061471
Pubmed

[ADAMTS family--new extracellular matrix degrading enzyme].

ADAMTS3 ADAMTS1

4.45e-05574211831030
Pubmed

Mouse Eya homologues of the Drosophila eyes absent gene require Pax6 for expression in lens and nasal placode.

EYA2 EYA3

4.45e-0557429006082
Pubmed

Mammalian BMP-1/Tolloid-related metalloproteinases, including novel family member mammalian Tolloid-like 2, have differential enzymatic activities and distributions of expression relevant to patterning and skeletogenesis.

TLL1 TLL2

4.45e-05574210479448
Pubmed

Cooperation of six and eya in activation of their target genes through nuclear translocation of Eya.

EYA2 EYA3

4.45e-05574210490620
Pubmed

Adamts5-/- Mice Exhibit Altered Aggrecan Proteolytic Profiles That Correlate With Ascending Aortic Anomalies.

MYLK ACAN

6.66e-05674231366218
Pubmed

EYA4, a novel vertebrate gene related to Drosophila eyes absent.

EYA2 EYA3

6.66e-0567429887327
Pubmed

ADAMTS1 cleaves aggrecan at multiple sites and is differentially inhibited by metalloproteinase inhibitors.

ADAMTS1 ACAN

6.66e-05674212054629
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

TRMT2A SUPT5H CHTF18 TLL1 PAPLN ELP2 CLSPN USP33

7.26e-0565074838777146
Pubmed

Association of gene polymorphisms with chronic kidney disease in Japanese individuals.

MARCHF10 OGDHL F10

8.00e-053974319724895
Pubmed

Chondroitin sulfate N-acetylgalactosaminyltransferase 1 is necessary for normal endochondral ossification and aggrecan metabolism.

ADAMTS1 ACAN

9.31e-05774221148564
Pubmed

Cloning and characterization of two vertebrate homologs of the Drosophila eyes absent gene.

EYA2 EYA3

9.31e-0577429049631
Pubmed

Expression of testicular germ cell genes identified by differential display analysis.

ANKRD18A ANKRD18B

1.24e-04874212634303
Pubmed

Rank-based genome-wide analysis reveals the association of ryanodine receptor-2 gene variants with childhood asthma among human populations.

KLHL5 XPR1

1.59e-04974223829686
Pubmed

ADAMTS: a novel family of extracellular matrix proteases.

ADAMTS10 ADAMTS3

1.99e-041074211167130
Pubmed

Hydrocephalus in mouse B3glct mutants is likely caused by defects in multiple B3GLCT substrates in ependymal cells and subcommissural organ.

ADAMTS3 ADAMTS20

2.43e-041174233909046
Pubmed

Combined genetic-pharmacologic inactivation of tightly linked ADAMTS proteases in temporally specific windows uncovers distinct roles for versican proteolysis and glypican-6 in cardiac development.

ADAMTS1 ACAN

2.43e-041174238750698
Pubmed

The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation.

NECAP2 WARS1 PIGK ZNF330 GLG1 PXN EYA3 NDRG3 USP33

2.83e-04100774934597346
Pubmed

MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity.

TRMT2A CIAO3 ELP2 EYA2

3.03e-0415074422678362
Pubmed

Vascular dimorphism ensured by regulated proteoglycan dynamics favors rapid umbilical artery closure at birth.

ADAMTS1 ACAN

3.43e-041374232909945
Pubmed

A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2.

CDK15 NBEAL1

3.43e-041374211586298
Pubmed

Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.

FGF23 ADAMTS3 ADAMTS20

3.51e-046474322261194
Pubmed

A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies.

GVINP1 CHTF18 SPTAN1 ARHGEF12 ICE1

3.56e-0428474529459677
Pubmed

Genetic dissection of plexin signaling in vivo.

ACAN ARHGEF12

4.61e-041574224469813
Pubmed

ADAMTS18 Deficiency Affects Neuronal Morphogenesis and Reduces the Levels of Depression-like Behaviors in Mice.

ADAMTS3 ADAMTS1

5.26e-041674230579834
Pubmed

Association analysis of 3p21 with Crohn's disease in a New Zealand population.

MST1 RNF123

5.95e-041774220307617
Pubmed

ADAM-TS5, ADAM-TS6, and ADAM-TS7, novel members of a new family of zinc metalloproteases. General features and genomic distribution of the ADAM-TS family.

ADAMTS3 ADAMTS1

5.95e-041774210464288
Pubmed

Fibulin-1 is required during cardiac ventricular morphogenesis for versican cleavage, suppression of ErbB2 and Erk1/2 activation, and to attenuate trabecular cardiomyocyte proliferation.

ADAMTS1 ADAMTS20

5.95e-041774222183742
Pubmed

Proteolysis of fibrillin-2 microfibrils is essential for normal skeletal development.

ADAMTS10 ACAN

6.68e-041874235503090
Pubmed

New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.

ACAN ZGRF1 SPTAN1 ADAMTS20 MINDY2 CBR3

7.94e-0451374625798074
Pubmed

ADAMTS metalloproteases generate active versican fragments that regulate interdigital web regression.

ADAMTS1 ADAMTS20

8.28e-042074219922873
Pubmed

Hundreds of variants clustered in genomic loci and biological pathways affect human height.

ADAMTS10 ADAMTS3 CIAO3 ACAN

8.59e-0419874420881960
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

MTMR4 NECAP2 PIGK ICE1 GPATCH8 CLSPN USP33

9.51e-0473374734672954
Pubmed

Smooth muscle contraction and relaxation.

MYLK PXN

1.00e-032274214627618
Pubmed

Myocardial Angiopoietin-1 Controls Atrial Chamber Morphogenesis by Spatiotemporal Degradation of Cardiac Jelly.

ADAMTS3 ADAMTS1

1.20e-032474229791855
Pubmed

Essential pro-Bmp roles of crossveinless 2 in mouse organogenesis.

ACAN KCP

1.30e-032574217035289
Pubmed

Genes and microRNAs associated with mouse cleft palate: A systematic review and bioinformatics analysis.

ACAN ADAMTS20

1.30e-032574229475039
Pubmed

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.

WARS1 NBEAL1 SPTAN1 PXN NDRG3 USP33

1.34e-0356874637774976
Pubmed

Dachshund homologues play a conserved role in islet cell development.

EYA2 EYA3

1.51e-032774220869363
Pubmed

Non-trisomic homeobox gene expression during craniofacial development in the Ts65Dn mouse model of Down syndrome.

ADAMTS1 CBR3

1.75e-032974223843306
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

KLHL5 ZNF600 WARS1 ZNF473 GLG1 OGDHL SPRED1 GPATCH8

2.12e-03108474811544199
CytobandEnsembl 112 genes in cytogenetic band chr19q13

ZNF600 ZNF473 SUPT5H USP29 ZNF611 ZNF576 ZNF808 IGFLR1 KLK1

1.27e-041192749chr19q13
Cytoband19q13.41

ZNF600 ZNF611 ZNF808

2.80e-047874319q13.41
Cytoband2q33.2

CDK15 NBEAL1

3.86e-04187422q33.2
GeneFamilyADAM metallopeptidases with thrombospondin type 1 motif

ADAMTS10 ADAMTS3 ADAMTS1 ADAMTS20

2.47e-071953450
GeneFamilyEYA transcriptional coactivator and phosphatases

EYA2 EYA3

5.04e-0545321044
GeneFamilyBone morphogenetic proteins|Astacins

TLL1 TLL2

1.26e-046532894
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF600 ZNF473 ZNF330 ZNF611 ZNF576 ZNF808 ZNF292 ZNF662

1.08e-0371853828
CoexpressionNABA_MATRISOME

ADAMTS10 MST1 FGF23 ADAMTS3 ADAMTS1 MUC17 PXDNL ACAN TLL1 TLL2 KCP ADAMTS20 PAPLN F10

9.26e-0710267414M5889
CoexpressionNABA_MATRISOME

ADAMTS10 MST1 FGF23 ADAMTS3 ADAMTS1 MUC17 ACAN TLL1 TLL2 KCP ADAMTS20 PAPLN F10

4.42e-0610087413MM17056
CoexpressionNABA_ECM_REGULATORS

ADAMTS10 ADAMTS3 ADAMTS1 TLL1 TLL2 ADAMTS20 F10

5.00e-06238747M3468
CoexpressionNABA_ECM_REGULATORS

ADAMTS10 ADAMTS3 ADAMTS1 TLL1 TLL2 ADAMTS20 F10

5.58e-06242747MM17062
CoexpressionNABA_MATRISOME_ASSOCIATED

ADAMTS10 MST1 FGF23 ADAMTS3 ADAMTS1 MUC17 TLL1 TLL2 ADAMTS20 F10

4.17e-057387410MM17058
CoexpressionNABA_MATRISOME_ASSOCIATED

ADAMTS10 MST1 FGF23 ADAMTS3 ADAMTS1 MUC17 TLL1 TLL2 ADAMTS20 F10

4.82e-057517410M5885
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MARCHF10 SYNE1 SAXO2 ANKRD18A CFAP70 ANKRD18B

8.64e-071947464a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCellBronchus_Control_(B.)-Epithelial-TX-Ciliated|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

MARCHF10 SYNE1 SAXO2 ANKRD18A CFAP70 ANKRD18B

1.03e-062007466a2ccc71a0cbe04a542c379b28b5006de53981c3
ToppCellLPS_only-Mesenchymal_myocytic-Pericyte|LPS_only / Treatment groups by lineage, cell group, cell type

MYLK ADAMTS1 NBEAL1 ACAN SYNE1 KCP

1.03e-062007468c8ef2b19ab5b1bfc0fae6c38a330f464f28e86f
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MARCHF10 ZGRF1 CHTF18 USP29 EYA2

5.16e-0615074547ea08d7609e1d2382bf56ef9e5c767e3597cf93
ToppCell5'-Adult-LymphNode-Mesenchymal-myocytic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYLK ADAMTS3 PAPLN EYA2 USP33

1.35e-05183745d67454baf0cf791a743b51afd1cb25bfb5765385
ToppCell5'-Adult-LymphNode-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYLK ADAMTS3 PAPLN EYA2 USP33

1.35e-05183745e49ac8314b6fe98426b1514ea68d646297b8bc0f
ToppCellPND10|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KLHL5 MYLK GLG1 SPTAN1 ARHGEF12

1.62e-05190745d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYLK ADAMTS1 ACAN SYNE1 KCP

1.66e-051917457853ac7dff649150e6ff27cd4c8cf7c1fc034ed4
ToppCellLPS-antiTNF-Stromal_mesenchymal|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYLK ADAMTS1 PXDNL SYNE1 EYA2

1.79e-051947456e13549f697f7478b34fe71f7dd9d63c5d3db22e
ToppCellLeuk-UTI-Lymphocyte-T_NK-NK|Leuk-UTI / Disease, Lineage and Cell Type

ZNF600 ADAMTS1 SYNE1 DENND2D GPATCH8

1.79e-0519474536afc4e48d267be3b8aa1e33fad043bcd54c6bc5
ToppCell10x5'-Lung-Lymphocytic_NK-NK_CD16|Lung / Manually curated celltypes from each tissue

ZNF600 ADAMTS1 SYNE1 PXN DENND2D

1.84e-05195745e91e7f89163c615b706f3297b641b1e4c966f5e6
ToppCell10x5'-Lung-Lymphocytic_NK|Lung / Manually curated celltypes from each tissue

ZNF600 ADAMTS1 SYNE1 PXN DENND2D

1.84e-05195745a5a10ef9254c266316e5591bec19e159cc3caead
ToppCellCOVID_vent-Lymphocytic-ILC|COVID_vent / Disease condition, Lineage, Cell class and subclass

ZNF600 ADAMTS1 SYNE1 ARHGEF12 DENND2D

2.02e-05199745e3ff7fa1b1de1aaf6b46cdf49afa95bad457728a
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

MYLK ADAMTS3 ADAMTS1 PXDNL SYNE1

2.02e-0519974530d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCellCOVID_vent-Lymphocytic-ILC-NK_cell|COVID_vent / Disease condition, Lineage, Cell class and subclass

ZNF600 ADAMTS1 SYNE1 ARHGEF12 DENND2D

2.02e-051997455f914962e2572b0c6372465b81b7496fa663d93c
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

MYLK ADAMTS3 ADAMTS1 PXDNL SYNE1

2.07e-052007459b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Pericyte|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

MYLK ADAMTS1 ACAN SYNE1 KCP

2.07e-05200745b22cae282591d8dead9869c2adbb9632615f50f7
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated|COVID-19_Mild / Disease, condition lineage and cell class

ADAMTS1 SYNE1 ARHGEF12 DENND2D GIMAP6

2.07e-052007452281debd86e5d92e8fe0397aec9ef670800f7471
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_only / Treatment groups by lineage, cell group, cell type

MYLK ADAMTS3 ADAMTS1 PXDNL EYA2

2.07e-05200745a7ef7022b8efcaedb7319b0b43d8c4e99d788fe2
ToppCellSepsis-Leuk-UTI-Lymphocyte-T/NK-NK|Leuk-UTI / Disease, condition lineage and cell class

ZNF600 ADAMTS1 SYNE1 DENND2D GPATCH8

2.07e-05200745bb37fed4872e71f413ae7c4aa12586fa31075334
ToppCellControl_saline-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|Control_saline / Treatment groups by lineage, cell group, cell type

MYLK ADAMTS3 PXDNL SYNE1 EYA2

2.07e-05200745bd8cf33502adea320e91ca2af14e1911d88ad374
ToppCellEntopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1|Entopeduncular / BrainAtlas - Mouse McCarroll V32

CASP12 MYLK CDK15 C3orf49

1.05e-0414774427e97a7b1dc296f52990b5810a52ab0a7ef2b9e6
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GVINP1 ZGRF1 CLSPN C3orf49

1.43e-0415974495128a2367ff2a639b21913c0350924c174faef8
ToppCell390C-Endothelial_cells-Endothelial-E|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

ZGRF1 ICE1 IGFLR1 DNAJB14

1.53e-0416274445be019b50e3727fc9d3fad2ff78e74e4f2d746b
ToppCell390C-Endothelial_cells-Endothelial-E-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

ZGRF1 ICE1 IGFLR1 DNAJB14

1.53e-04162744fbb0cc2b1434a340dc35058b77c73ea61004c252
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CASP12 MYLK CHTF18 CLSPN

1.72e-04167744784776d1fcc098f84d3c2eca58fa56cb9428f434
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-like-AT2_Progenitor|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAMTS3 ZNF611 PAPLN DENND2D

1.76e-041687449e7b4b9b977e90e083f5164013e79df8bc2d492e
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb-18m-Lymphocytic-T_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND2D IGFLR1 GIMAP6 USP33

1.76e-04168744182f08106ac65ea501e2fb9139d3b44b7c4662c9
ToppCell10x3'2.3-week_12-13-Lymphocytic_T-T_NK-Treg|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

RNF123 APBA3 DENND2D IGFLR1

1.76e-0416874499117480687e2b8e7521d3ae9e020791757ec48e
ToppCell10x5'-GI_small-bowel-Lymphocytic_NK-NK_CD16|GI_small-bowel / Manually curated celltypes from each tissue

ADAMTS10 ADAMTS1 SYNE1 PXN

1.88e-041717441ee505b91f15191d294a5d491ecdf154c08b8622
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ACAN ZGRF1 CHTF18 CLSPN

1.88e-04171744b0373ed8283ee1792b6a490bff93906546978593
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ACAN ZGRF1 CHTF18 CLSPN

1.88e-04171744b92963f9f247d2e5e2e6c51c6dbf70e527cd2f55
ToppCellCOVID-19-kidney-PEC|kidney / Disease (COVID-19 only), tissue and cell type

MYLK ADAMTS3 SYNE1 PAPLN

1.93e-0417274436a96714a0eb6ac438648135336c9791881ddadb
ToppCell367C-Fibroblasts-Fibroblast-J_(Lipofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

TLL1 OGDHL ANKRD18A KLK1

1.97e-041737443d7c281a1a9f183a5a861d1a9c7b50d216535893
ToppCell368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

KLHL5 ZGRF1 CLSPN ZNF662

1.97e-0417374420889aa85e36ad3bafdb91b91e43964493c949f9
ToppCell368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

KLHL5 ZGRF1 CLSPN ZNF662

1.97e-0417374446e601b7938b1dd0aa3df7aa056c4bd07b1620c1
ToppCell367C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

TLL1 OGDHL ANKRD18A KLK1

1.97e-041737443aa90578371039f81b7c6fa873ec70f8f2bc7dfa
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CASP12 CDK15 ACAN C3orf49

2.01e-04174744778e0317c0c63fa4efd74114feb760975b819d92
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ADAMTS1 SYNE1 ICE1 MINDY2

2.15e-04177744d3e6c768b88b7906f3c7fdd00ba20842212c14b1
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ADAMTS1 SYNE1 ICE1 MINDY2

2.15e-04177744f8f101c772c043636bedd6b2ec81409b1d2599bf
ToppCellCOVID-19_Mild-Lymphoid_T/NK-NK_activated|COVID-19_Mild / Disease group, lineage and cell class

ADAMTS1 SYNE1 ICE1 MINDY2

2.15e-041777446978a22fef40c8b455342373abe7593f5ede0fa4
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

ADAMTS1 SYNE1 ICE1 MINDY2

2.15e-04177744936ab2b180a052387124f68d0c7f41c0b164e748
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ADAMTS1 SYNE1 ICE1 MINDY2

2.15e-04177744d5aeda113afaa2425874394610344570c9078478
ToppCelldroplet-Lung-nan-3m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF473 ZGRF1 CHTF18 CLSPN

2.20e-04178744de6cd81e6d58e7687386df163471bf1901b9c0aa
ToppCell10x3'2.3-week_17-19-Lymphocytic_T-T_NK-NK_T_cell|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ADAMTS10 CDK15 NBEAL1 GIMAP6

2.20e-04178744a34bb693b72684cbd97ac9efff77d2d14e41be75
ToppCell368C-Myeloid-Dendritic-cDC_proliferating_1|368C / Donor, Lineage, Cell class and subclass (all cells)

ZGRF1 CHTF18 ZNF611 CLSPN

2.24e-04179744ec69e1dd897414033ba5b007aa82655a79adca6c
ToppCellCOVID-19-kidney-vSMC/Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

MYLK ADAMTS1 NBEAL1 ACAN

2.24e-04179744111b1084f73306bdeffaaf240e7dbb4f5bf33de1
ToppCell368C-Lymphocytic-ILC-ILC-2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ZNF611 SERINC2 MINDY2 CBR3

2.29e-04180744eb5a57604c7f2ad256c300085dbf5069d0ae1ad0
ToppCell368C-Lymphocytic-ILC|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ZNF611 SERINC2 MINDY2 CBR3

2.29e-04180744ddba4dc3bbcfe4e4a22400be73bbc62d3ff27d3c
ToppCelldroplet-Lung-nan-18m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF473 ZGRF1 CLSPN IGFLR1

2.29e-0418074443fd5c498a87bb078d101298b472656f3294686a
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MARCHF10 ZNF473 SAXO2 CFAP70

2.34e-04181744dfce05bd472f67e6e2bb60ebd6fd34f0a9aeeca6
ToppCellwk_08-11-Mesenchymal-Chondrocyte-Resting_chondrocyte|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

GLG1 ACAN CFAP70 EYA2

2.39e-0418274400a148b1e499bf16325491536d187d4dd6b70c06
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L5-6_SST_ISOC1|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KLHL5 TLL2 KCP ADAMTS20

2.44e-041837447961e05c6e9964da159059c6bfb4f7e7e14308c2
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Fibromyocytes|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MYLK ADAMTS1 PXDNL ACAN

2.49e-0418474454e5b63f55b8d6eccad53d389ea9c78f991e1414
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-SM_activated_stress_response|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MYLK ADAMTS1 ACAN F10

2.49e-04184744603faafb7b289a3c0242c84fc800c050c8a092ea
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Fibromyocytes-Fibromyocytes_L.2.3.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MYLK ADAMTS1 PXDNL ACAN

2.49e-041847447b5678718719020b52e7c2a7bd9797987defd7ff
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-SM_activated_stress_response-SM_activated_stress_response_L.2.3.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MYLK ADAMTS1 ACAN F10

2.49e-04184744c350504bfe0ec31cd2fc2199de9b5fff151a8c5e
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYLK ADAMTS1 KCP PAPLN

2.49e-04184744327ff3ac8d2fecdd5d242bdc34f0dfdb1c59a68b
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L5-6_SST_ISOC1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KLHL5 TLL2 KCP ADAMTS20

2.54e-04185744ae53aa2ecfe418a5dbd7d963a995bc06dab94f56
ToppCell368C-Myeloid-Dendritic-cDC_proliferating_1|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

ZGRF1 CHTF18 ZNF611 CLSPN

2.60e-04186744799903b68bc6f6205d004b44c603424b0d5f7c32
ToppCellNS-critical-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MARCHF10 SAXO2 ANKRD18A CFAP70

2.60e-0418674476033438426d8f9c72cd6691a7baf92104c9f03d
ToppCell10x5'v1-week_12-13-Lymphocytic_NK-T_NK-mature_NK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

ADAMTS1 SYNE1 DENND2D GIMAP6

2.60e-04186744165d02be3b3eaeb8784a2b0b2020928b21a19bc7
ToppCellASK440-Immune-NK_cell|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

ZNF600 ADAMTS1 SYNE1 PXN

2.60e-04186744ce8e63057a99afa0a9cbf27ae7f9a70c0e972b6d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KLHL5 WARS1 TLL1 CLSPN

2.65e-0418774435c382c0aabd46906113e5db30ea24bb8e658899
ToppCellCiliated_cells-B-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

SAXO2 ANKRD18A CFAP70 ANKRD18B

2.65e-041877446fa38dbccca36bc7a4fef46de74c6688f599f421
ToppCellCOPD-Endothelial-VE_Capillary_A|Endothelial / Disease state, Lineage and Cell class

KLHL5 MYLK SYNE1 KLK1

2.70e-041887441aa0e35b1c28ac847886fece16c3ef7fc6fcdd51
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

MYLK ADAMTS1 PXDNL EYA2

2.70e-04188744f54b063025d80de631382bf5326bc40aab7f7d00
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

MYLK ADAMTS1 PXDNL EYA2

2.81e-04190744938d1f66094b1c94606e0d40213a39e5112f3322
ToppCelldroplet-Lung-LUNG-30m-Endothelial-endothelial_cell_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLHL5 ADAMTS1 SYNE1 ARHGEF12

2.81e-04190744e64b191f928935484e2c993d7f8af0572a617a3a
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYLK ADAMTS3 PXDNL EYA2

2.87e-04191744b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCelldroplet-Trachea-3m-Epithelial-airway_epithelial-neuroendocrine_cell-neuroendocrine|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MYLK CDK15 ADAMTS1 ADAMTS20

2.87e-0419174472f1ddc09080dbfea8d51294cbf7f9d4925f9cc0
ToppCelldroplet-Trachea-3m-Epithelial-airway_epithelial-neuroendocrine_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MYLK CDK15 ADAMTS1 ADAMTS20

2.87e-041917446e7f589efc997f32175e0789c5ea7ca46e1389b8
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MYLK ADAMTS1 TLL2 KCP

2.87e-041917449032aa974aa1b7b1095b8d1b58dcb087358a5001
ToppCelldroplet-Trachea-nan-3m-Epithelial-neuroendocrine_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYLK CDK15 ADAMTS1 ADAMTS20

2.87e-041917443ce403e0beedb544edeb3ae6eb30267040d00c21
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MYLK ADAMTS1 TLL2 KCP

2.87e-041917445717809a1476c20f65bce722c5a57cff92ee0d7a
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYLK ADAMTS3 PXDNL EYA2

2.93e-041927446f4ef24dab544681304b7f8a9dc073e7edaa4cf5
ToppCellPericytes|World / lung cells shred on cell class, cell subclass, sample id

MYLK ADAMTS1 ACAN F10

2.93e-04192744057ad22b878c0c5fb59ed1412ca13db945c57a5a
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYLK ADAMTS1 PXDNL EYA2

2.93e-041927443d0cb19f037f604253d7d728689aeaa94251e92b
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KLHL5 TLL2 KCP ADAMTS20

2.99e-04193744d1445b8bf2bab36e1a326ddb2a528151db016c7d
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KLHL5 TLL2 KCP ADAMTS20

2.99e-04193744010717ca052b6c8a525a43aaeffddea0d1113e63
ToppCellTransplant_Alveoli_and_parenchyma-Mesenchymal-Smooth_muscle|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

MYLK ADAMTS1 ACAN F10

2.99e-041937449104b572d9c3c99080e4b7455993fbb944bf117d
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KLHL5 TLL2 KCP ADAMTS20

2.99e-04193744e74fdc8718fe0933e1f4dd3fe37e2134983b99b6
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_NK-natural_killer_cell|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

ADAMTS1 SYNE1 DENND2D GPATCH8

3.05e-04194744a3a81638b55cb5fc08fe83c8b88f68d49b87e6cb
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MYLK CDK15 ADAMTS1 F10

3.05e-041947445f5f0cdeacd5e1b28717d78dabdb9eb95f661e36
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAMTS3 PXDNL SYNE1 EYA2

3.05e-0419474460622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCellIPF-Endothelial-VE_Capillary_A|Endothelial / Disease state, Lineage and Cell class

KLHL5 MYLK GVINP1 SYNE1

3.05e-04194744777ce41c3f22c591e2d81120f189b834e53ffb4b
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_NK-natural_killer_cell-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

ADAMTS1 SYNE1 DENND2D GPATCH8

3.05e-041947440abca32c3547a45cebab0bd69c1f7a0002deaa80
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYLK ADAMTS3 PXDNL EYA2

3.05e-0419474489b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCellT_cells-CD56_dim_CD16+_NK_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

ADAMTS1 SYNE1 PXN DENND2D

3.05e-04194744335c6c2f3f319d4f19eace62f8826a0f40c130f6
ToppCellIPF-Multiplet-Multiplet|IPF / Disease state, Lineage and Cell class

SYNE1 ARHGEF12 SAXO2 CFAP70

3.11e-04195744fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Smooth_muscle-Smooth_muscle_L.2.3.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MYLK ADAMTS1 ACAN F10

3.11e-041957447155cc12cc6a97efd626bbdb95249fb3d7041dcf
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MYLK ADAMTS1 ACAN F10

3.11e-04195744a52ee3ad6cd317f10b9308450517861ef2e363bb
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Smooth_muscle|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MYLK ADAMTS1 ACAN F10

3.11e-04195744b3660779f274ca97dd844cf83f62d85ba88cb182
ToppCellIPF-Multiplet|IPF / Disease state, Lineage and Cell class

SYNE1 ARHGEF12 SAXO2 CFAP70

3.11e-04195744eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCell(3)_MNP-(3)_Macrophage_MARCOneg|(3)_MNP / Lung cell shreds - cell class (v4) and cell subclass (v4)

SYNE1 SPRED1 EYA2 GIMAP6

3.11e-04195744e4b5e4b8832669fb4d1661ecd828b81e621d35c4
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

MARCHF10 SYNE1 SAXO2 CFAP70

3.11e-041957443486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCellCOPD-Multiplet-Multiplet|COPD / Disease state, Lineage and Cell class

SYNE1 ARHGEF12 SAXO2 CLSPN

3.17e-04196744af4cdc61830685a888a1209826c23bcf54a43084
ToppCellCOVID-19-lung-Capillary_Aerocytes|COVID-19 / Disease (COVID-19 only), tissue and cell type

KLHL5 WARS1 SYNE1 ARHGEF12

3.17e-0419674449cc0a2b9739abad61dff7292ea0b14d28ff35c4
ToppCell10x5'-Liver-Lymphocytic_NK-NK_CD16|Liver / Manually curated celltypes from each tissue

ADAMTS10 ADAMTS1 SYNE1 PXN

3.17e-04196744e6d4853ccefbcd45a019cee595811f0474dcc036
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MYLK ADAMTS1 ACAN F10

3.17e-041967448c25fa61c117a60ddd4cbd2f95ae5b66f986a1ec
Diseaseeye disease (implicated_via_orthology)

EYA2 EYA3

9.00e-056732DOID:5614 (implicated_via_orthology)
Diseasebody composition measurement

ADAMTS10 NBEAL1 PXDNL ACAN EYA2

1.19e-04193735EFO_0005106
Diseasebranchiootorenal syndrome (implicated_via_orthology)

EYA2 EYA3

1.26e-047732DOID:14702 (implicated_via_orthology)
Diseasetumor necrosis factor ligand superfamily member 6, soluble form measurement

MST1 RNF123

1.26e-047732EFO_0020797
Diseasedental caries

MTMR4 ADAMTS3 ZGRF1 F10

1.21e-03187734EFO_0003819

Protein segments in the cluster

PeptideGeneStartEntry
QELCGVEDDFHNQFA

CHTF18

6

Q8WVB6
FANEDFSCHGDLNTD

ANKRD18A

721

Q8IVF6
DRFDNCVTFTNLHGD

GVINP1

1111

Q7Z2Y8
GDLDHFSNSDNCREV

APBA3

381

O96018
ANEDFSCHGDLNTDQ

ANKRD18B

731

A2A2Z9
LHDDTIFEIFNNRNC

CASP12

191

Q6UXS9
QAYDADEQCRFQHGV

ADAMTS10

471

Q9H324
NFGHRLADNECQELS

ADAMTS20

996

P59510
DDFGTEHEQINGQCS

ARHGEF12

356

Q9NZN5
QLQSGRFDCADRQFH

NBEAL1

2121

Q6ZS30
NNGKTFREEQCEAHN

ADAMTS1

616

Q9UHI8
ADTHLFFNDLEECDQ

EYA3

351

Q99504
GTRNFQDFDCQEHDI

NDRG3

21

Q9UGV2
ESRHFQIDYDEDGNC

MYLK

1851

Q15746
GRHNLFDDENTAQFV

KLK1

76

P06870
SRFNEDRDFQGNHFD

GPATCH8

6

Q9UKJ3
EAQFGDFHNTAQCII

OGDHL

731

Q9ULD0
NGDETAVEDFCNNFR

JRKL

146

Q9Y4A0
CTSDEFFQALNHAEQ

KLHL5

191

Q96PQ7
EDQAEQFFRSGHTNN

PIGK

31

Q92643
GDRCGHQENVEDQNE

MTMR4

451

Q9NYA4
EQLQAAYEDGFHQCD

ACAN

186

P16112
HCQEEIGSRNFFERD

PXN

386

P49023
DRAAQHDQGQYECQA

PXDNL

476

A1KZ92
QNFCHDVADNQIDSG

GLG1

701

Q92896
NTEECQKHFEDFRAQ

ADAMTS3

601

O15072
NCSSDHVFNENGNLE

ICE1

291

Q9Y2F5
QRHAELQQCEFLGDE

C3orf49

246

Q96BT1
NSDCFQEEDLRQGFQ

CDK15

76

Q96Q40
QNNGRFNFHRGCEAD

DNAJB14

181

Q8TBM8
NHPEDSEFRNQAECI

CFAP70

261

Q5T0N1
ENCRFQHQTLENGYD

FGF23

111

Q9GZV9
FRENCGLNDHGDFVT

IGFLR1

56

Q9H665
NFEENAENCRGHSSR

MARCHF10

331

Q8NA82
AFENCSEDLQERFHS

CBR3

146

O75828
RHCDEVGFNAEEAHN

DYNLT3

6

P51808
GNDDCRIHIFAQQND

ELP2

181

Q6IA86
HAQLEENFCRNPDGD

MST1

411

P26927
LDNGDCDQFCHEEQN

F10

131

P00742
REANGQGHFQERSFC

DENND2D

396

Q9H6A0
QNIGFDICQDDDSIH

MUC17

4446

Q685J3
ADTHLFFNDLEDCDQ

EYA2

316

O00167
QEGELCVFFRNNHFS

MINDY2

436

Q8NBR6
RFQQDDAHIFCTVEQ

TARS3

536

A2RTX5
RDTIEEHRQFGGNCD

WARS1

381

P23381
DNELSNVEFHCGRAE

TRMT2A

476

Q8IZ69
GLTFQSFEIERHDNC

TLL1

501

O43897
QDCASELGSFEDQHR

SYNE1

2511

Q8NF91
HCGFNNRAQGEEQEA

GIMAP6

196

Q6P9H5
SCLSQGREHQDGEEF

KCP

901

Q6ZWJ8
REHNFQPGDNVEVCE

SUPT5H

416

O00267
ATDFQGNDFDNDHNR

SSX1

76

Q16384
PDFFNQEHQTRDVDC

CIAO3

256

Q9H6Q4
ESNFLGNNHSEECQV

CLSPN

431

Q9HAW4
RLENEHLNNCGEFRA

XPR1

611

Q9UBH6
FRAEQCAEFDGAEFQ

PAPLN

86

O95428
CRFNQEEGVGDTHNS

RNF123

156

Q5XPI4
ARQFQDAGHFDAENI

SPTAN1

741

Q13813
RFNHEENVRGKCQDA

SPRED1

341

Q7Z699
FQERKEQDCFNDAHV

ZNF292

986

O60281
LTFNEFEIEQHQECA

TLL2

816

Q9Y6L7
FQRDCGDASQEQHQR

USP29

606

Q9HBJ7
HNIEFQCQEDERNGH

ZNF808

111

Q8N4W9
QRFEDLTTHRCDFQG

SAXO2

176

Q658L1
CEGREDGLQHANQYE

ZGRF1

2056

Q86YA3
HDIEFQCQEDERNGL

ZNF611

111

Q8N823
NFLCEDDQFEHQASC

ZNF330

151

Q9Y3S2
DDQFEHQASCQVLEA

ZNF330

156

Q9Y3S2
TECGQDFAQEAGLHQ

ZNF576

146

Q9H609
IHDIEFQCQEDERNG

ZNF600

41

Q6ZNG1
QQQVAACEGRAFDNE

SERINC2

366

Q96SA4
ENENGSRCFSEDNNE

USP33

331

Q8TEY7
ECGKCFDQNEDFDQH

ZNF662

196

Q6ZS27
PTVHQECEQGFDRNA

ZNF473

236

Q8WTR7
DRGDAFDFNVALQDH

NECAP2

111

Q9NVZ3