Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionL-glutamate uniporter activity

SLC17A8 SLC17A7

3.80e-063232GO:0140788
GeneOntologyMolecularFunctionmembrane potential driven uniporter activity

SLC17A8 SLC17A7

1.27e-055232GO:0022810
GeneOntologyMolecularFunctionuniporter activity

SLC17A8 SLC17A7

5.68e-0510232GO:0015292
GeneOntologyMolecularFunctionsodium:phosphate symporter activity

SLC17A8 SLC17A7

8.32e-0512232GO:0005436
GeneOntologyMolecularFunctionL-glutamate transmembrane transporter activity

SLC17A8 SLC17A7

1.32e-0415232GO:0005313
GeneOntologyMolecularFunctionacidic amino acid transmembrane transporter activity

SLC17A8 SLC17A7

2.38e-0420232GO:0015172
GeneOntologyMolecularFunctionneurotransmitter transmembrane transporter activity

SLC17A8 SLC17A7

2.63e-0421232GO:0005326
GeneOntologyMolecularFunctionphosphate transmembrane transporter activity

SLC17A8 SLC17A7

3.45e-0424232GO:0005315
GeneOntologyMolecularFunctionmetal cation:proton antiporter activity

SLC17A7 SLC9B2

4.38e-0427232GO:0051139
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC17A8 SLC17A7 SLC9B2

9.63e-04171233GO:0015081
GeneOntologyMolecularFunctionmetal cation:monoatomic cation antiporter activity

SLC17A7 SLC9B2

1.11e-0343232GO:0140828
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

SLC17A8 SLC17A7 ABCB11

1.67e-03207233GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

SLC17A8 SLC17A7 ABCB11

1.69e-03208233GO:0005342
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC17A8 SLC17A7 ABCB11 SLC9B2

1.99e-03477234GO:0022804
GeneOntologyMolecularFunctionL-amino acid transmembrane transporter activity

SLC17A8 SLC17A7

3.01e-0371232GO:0015179
GeneOntologyMolecularFunctionsolute:sodium symporter activity

SLC17A8 SLC17A7

3.89e-0381232GO:0015370
GeneOntologyMolecularFunctionchloride channel activity

SLC17A8 SLC17A7

4.37e-0386232GO:0005254
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLC17A8 SLC17A7 ABCB11

4.46e-03293233GO:0008514
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC17A8 SLC17A7 SLC9B2

4.58e-03296233GO:0015291
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

SLC17A8 SLC17A7 SLC9B2

4.80e-03301233GO:0022853
GeneOntologyMolecularFunctionmonoatomic anion channel activity

SLC17A8 SLC17A7

6.21e-03103232GO:0005253
GeneOntologyMolecularFunctionamino acid transmembrane transporter activity

SLC17A8 SLC17A7

6.45e-03105232GO:0015171
GeneOntologyMolecularFunctionsolute:monoatomic cation symporter activity

SLC17A8 SLC17A7

8.21e-03119232GO:0015294
GeneOntologyMolecularFunctionchloride transmembrane transporter activity

SLC17A8 SLC17A7

9.03e-03125232GO:0015108
GeneOntologyMolecularFunctionsteroid binding

GPR155 IGF1

1.02e-02133232GO:0005496
GeneOntologyMolecularFunctionantiporter activity

SLC17A7 SLC9B2

1.09e-02138232GO:0015297
GeneOntologyMolecularFunctionsymporter activity

SLC17A8 SLC17A7

1.28e-02150232GO:0015293
GeneOntologyMolecularFunctionmonoatomic anion transmembrane transporter activity

SLC17A8 SLC17A7

1.30e-02151232GO:0008509
GeneOntologyBiologicalProcessneurotransmitter loading into synaptic vesicle

SLC17A8 SLC17A7

6.50e-0511232GO:0098700
GeneOntologyBiologicalProcesscognition

BRAF SLC17A7 GPR155 IGF1 DRD5

8.79e-05423235GO:0050890
GeneOntologyBiologicalProcesssodium-dependent phosphate transport

SLC17A8 SLC17A7

9.21e-0513232GO:0044341
GeneOntologyCellularComponentexocytic vesicle

AP2A2 SLC17A8 SLC17A7 IGF1 SLC9B2

2.19e-05320235GO:0070382
GeneOntologyCellularComponentclathrin-sculpted glutamate transport vesicle

SLC17A8 SLC17A7

4.15e-059232GO:0060199
GeneOntologyCellularComponentclathrin-sculpted glutamate transport vesicle membrane

SLC17A8 SLC17A7

4.15e-059232GO:0060203
GeneOntologyCellularComponentclathrin-sculpted vesicle

SLC17A8 SLC17A7

1.38e-0416232GO:0060198
GeneOntologyCellularComponenttransport vesicle

AP2A2 SLC17A8 SLC17A7 IGF1 SLC9B2

2.15e-04519235GO:0030133
GeneOntologyCellularComponentsynaptic vesicle

AP2A2 SLC17A8 SLC17A7 SLC9B2

2.97e-04300234GO:0008021
GeneOntologyCellularComponentpresynapse

AP2A2 BRAF SLC17A8 SLC17A7 ADGRL1 SLC9B2

3.09e-04886236GO:0098793
GeneOntologyCellularComponentclathrin-coated vesicle membrane

AP2A2 SLC17A8 SLC17A7

5.44e-04147233GO:0030665
GeneOntologyCellularComponentexocytic vesicle membrane

SLC17A8 SLC17A7 SLC9B2

9.64e-04179233GO:0099501
GeneOntologyCellularComponentsynaptic vesicle membrane

SLC17A8 SLC17A7 SLC9B2

9.64e-04179233GO:0030672
GeneOntologyCellularComponentcoated vesicle membrane

AP2A2 SLC17A8 SLC17A7

1.63e-03215233GO:0030662
GeneOntologyCellularComponentglutamatergic synapse

BRAF SLC17A8 ADGRL1 IGF1 DRD5

1.69e-03817235GO:0098978
GeneOntologyCellularComponentchloride channel complex

SLC17A8 SLC17A7

1.78e-0357232GO:0034707
GeneOntologyCellularComponentclathrin-coated vesicle

AP2A2 SLC17A8 SLC17A7

2.16e-03237233GO:0030136
GeneOntologyCellularComponentcilium

HYDIN TTLL11 FHDC1 DRD5 SLC9B2

2.55e-03898235GO:0005929
GeneOntologyCellularComponentcell body

BRAF SLC17A8 SRR IGF1 DRD5

2.96e-03929235GO:0044297
GeneOntologyCellularComponenttransport vesicle membrane

SLC17A8 SLC17A7 SLC9B2

3.92e-03293233GO:0030658
GeneOntologyCellularComponentexcitatory synapse

SLC17A8 SLC17A7

6.12e-03107232GO:0060076
GeneOntologyCellularComponentrecycling endosome membrane

ABCB11 SLC9B2

6.69e-03112232GO:0055038
GeneOntologyCellularComponentcoated vesicle

AP2A2 SLC17A8 SLC17A7

6.95e-03360233GO:0030135
GeneOntologyCellularComponentsecretory vesicle

AP2A2 SLC17A8 SLC17A7 IGF1 SLC9B2

1.02e-021246235GO:0099503
MousePhenodecreased synaptic glutamate release

SLC17A8 ADGRL1

5.42e-058202MP:0004495
MousePhenoabnormal neurotransmitter uptake

SLC17A8 SLC17A7

5.42e-058202MP:0003444
MousePhenoabnormal synaptic glutamate release

SLC17A8 ADGRL1

1.50e-0413202MP:0004494
DomainRasGEF_N

RASGEF1C RASGEF1A

3.00e-0421232PF00618
DomainRASGEF_NTER

RASGEF1C RASGEF1A

3.30e-0422232PS50212
DomainRas-like_Gua-exchang_fac_N

RASGEF1C RASGEF1A

3.30e-0422232IPR000651
DomainRASGEF

RASGEF1C RASGEF1A

4.63e-0426232PS00720
DomainRASGEF_CAT

RASGEF1C RASGEF1A

5.77e-0429232PS50009
DomainRasGEF

RASGEF1C RASGEF1A

6.18e-0430232PF00617
Domain-

RASGEF1C RASGEF1A

6.18e-04302321.10.840.10
DomainRas_GEF_dom

RASGEF1C RASGEF1A

6.18e-0430232IPR023578
DomainRASGEF_cat_dom

RASGEF1C RASGEF1A

6.18e-0430232IPR001895
DomainRasGEF

RASGEF1C RASGEF1A

6.18e-0430232SM00147
DomainMFS

SLC17A8 SLC17A7

4.01e-0377232IPR011701
DomainMFS_1

SLC17A8 SLC17A7

4.01e-0377232PF07690
DomainMFS

SLC17A8 SLC17A7

7.74e-03108232PS50850
DomainMFS_dom

SLC17A8 SLC17A7

1.17e-02134232IPR020846
PathwayWP_SYNAPTIC_VESICLE_PATHWAY

AP2A2 SLC17A8 SLC17A7

4.87e-0551203M39457
PathwayREACTOME_ORGANIC_ANION_TRANSPORTERS

SLC17A8 SLC17A7

1.25e-0412202M27350
PathwayREACTOME_ORGANIC_ANION_TRANSPORTERS

SLC17A8 SLC17A7

1.25e-0412202MM15087
PathwayKEGG_MEDICUS_REFERENCE_IGF_IGF1R_RAS_ERK_SIGNALING_PATHWAY

BRAF IGF1

2.27e-0416202M47483
Pubmed

Synaptic and extrasynaptic factors governing glutamatergic retinal waves.

SLC17A8 SLC17A7

4.18e-07223219409268
Pubmed

AP2 adaptor complex mediates bile salt export pump internalization and modulates its hepatocanalicular expression and transport function.

AP2A2 ABCB11

1.25e-06323222262466
Pubmed

Lack of evidence for vesicular glutamate transporter expression in mouse astrocytes.

SLC17A8 SLC17A7

1.25e-06323223467360
Pubmed

Vesicular Glutamate Transporters (SLCA17 A6, 7, 8) Control Synaptic Phosphate Levels.

SLC17A8 SLC17A7

1.25e-06323233440152
Pubmed

Docking and homology modeling explain inhibition of the human vesicular glutamate transporters.

SLC17A8 SLC17A7

1.25e-06323217660252
Pubmed

Protocol to map multi-transmitter neurons in the mouse brain using intersectional strategy.

SLC17A8 SLC17A7

4.18e-06523236595933
Pubmed

Enteroendocrine cell types that drive food reward and aversion.

SLC17A8 SLC17A7

1.50e-05923235913117
Pubmed

The G protein-coupled receptor repertoires of human and mouse.

GPR155 ADGRL1 DRD5

1.93e-057923312679517
Pubmed

Intersectional mapping of multi-transmitter neurons and other cell types in the brain.

SLC17A8 SLC17A7

4.99e-051623235793636
Pubmed

A genetic linkage map of mouse chromosome 10: localization of eighteen molecular markers using a single interspecific backcross.

BRAF IGF1

5.66e-05172321975791
Pubmed

Enhancer viruses for combinatorial cell-subclass-specific labeling.

SLC17A8 SLC17A7

7.89e-052023233789083
Pubmed

Class 5 transmembrane semaphorins control selective Mammalian retinal lamination and function.

SLC17A8 SLC17A7

8.72e-052123221835343
Pubmed

Sidekick 2 directs formation of a retinal circuit that detects differential motion.

SLC17A8 SLC17A7

1.05e-042323226287463
Pubmed

Excitatory neurons of the proprioceptive, interoceptive, and arousal hindbrain networks share a developmental requirement for Math1.

SLC17A8 SLC17A7

1.45e-042723220080794
Pubmed

Roof Plate-Derived Radial Glial-like Cells Support Developmental Growth of Rapidly Adapting Mechanoreceptor Ascending Axons.

SLC17A7 IGF1

1.68e-042923229874580
Pubmed

Scaled, high fidelity electrophysiological, morphological, and transcriptomic cell characterization.

SLC17A8 SLC17A7

2.05e-043223234387544
Pubmed

A taxonomy of transcriptomic cell types across the isocortex and hippocampal formation.

SLC17A8 SLC17A7

2.32e-043423234004146
Pubmed

Choroid plexuses carry nodal-like cilia that undergo axoneme regression from early adult stage.

HYDIN TTLL11

2.46e-043523237890489
Pubmed

Diverse spinal commissural neuron populations revealed by fate mapping and molecular profiling using a novel Robo3Cre mouse.

SLC17A8 SLC17A7

3.21e-044023231152445
Pubmed

Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub.

AP2A2 SLC17A7 ADGRL1

3.77e-0421523336808153
Pubmed

Tuning of Glutamate, But Not GABA, Release by an Intrasynaptic Vesicle APP Domain Whose Function Can Be Modulated by β- or α-Secretase Cleavage.

AP2A2 SLC17A7

4.44e-044723231235642
Pubmed

The Allen Mouse Brain Common Coordinate Framework: A 3D Reference Atlas.

SLC17A8 SLC17A7

4.63e-044823232386544
Pubmed

Regional and cell-type-specific afferent and efferent projections of the mouse claustrum.

SLC17A8 SLC17A7

5.03e-045023236774552
Pubmed

Calsyntenins function as synaptogenic adhesion molecules in concert with neurexins.

SLC17A7 ADGRL1

5.44e-045223224613359
CytobandEnsembl 112 genes in cytogenetic band chr12q23

SLC17A8 ALDH1L2 IGF1

5.77e-05150233chr12q23
GeneFamilySolute carriers

SLC17A8 SLC17A7 SLC9B2

4.69e-03395163752
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)|Hippocampus / BrainAtlas - Mouse McCarroll V32

SLC17A7 RASGEF1A SRR DRD5

1.57e-061682346db453cbbbaf4144a86fadcfa5805d33396713b5
ToppCellFrontal_cortex-Neuronal-Excitatory|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

SLC17A7 RASGEF1A SRR DRD5

2.26e-061842346e17c8151d6dc543de16d804db956c63c3fda414
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Lhx8-Inhibitory_Neuron.Gad1Gad2-Chat_(Nucleus_basalis_(NB))-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

RASGEF1C SLC17A8 DRD5

2.63e-0511323334ae3dec5ec7585d155ea61de6adc42aa4f45226
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Lhx8-Inhibitory_Neuron.Gad1Gad2-Chat_(Nucleus_basalis_(NB))|Entopeduncular / BrainAtlas - Mouse McCarroll V32

RASGEF1C SLC17A8 DRD5

2.63e-0511323379ba2eb8f85e5da4c19c838df881c18ffdc450fb
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Lhx8|Entopeduncular / BrainAtlas - Mouse McCarroll V32

RASGEF1C SLC17A8 DRD5

2.63e-0511323391d55fe6fb1c1472867d74461f5b9e4f17db01cd
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-4_VIP_CHRNA2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TCHH SLFN11 IGF1

6.75e-05155233523a821963d2aecb67da7133a9a4b3bc33309b58
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L6_IT|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RASGEF1C DRD5 SLC9B2

7.15e-051582339e0589f770920f8ac41cfe5cd0a29e9e7a04a308
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Cbln4_Fezf2|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RASGEF1C SLC17A7 SLC9B2

7.42e-05160233d8241404d775f9a709abdf17988f36293fcf4c58
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_IT|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RASGEF1C SLC17A7 SLC9B2

8.42e-05167233f1ce6e64ebede1f3ef36fe982f46919fd1f814dd
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-like-AT2_Progenitor|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GPR155 TTLL11 IGF1

8.57e-051682339e7b4b9b977e90e083f5164013e79df8bc2d492e
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_VISp_Penk_Col27a1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RASGEF1C SLC17A7 SLC9B2

9.03e-05171233d07e2c5f7d7f12c68860d4161d76372de174f1d8
ToppCellTCGA-Colorectal-Solid_Tissue_Normal-Colon_normal_tissue|TCGA-Colorectal / Sample_Type by Project: Shred V9

SLC17A8 SLC17A7 ABCB11

9.19e-0517223394842346c84542a5243bd765e49f4af8bc5182db
ToppCellTCGA-Colorectal-Solid_Tissue_Normal-Colon_normal_tissue-Colon_normal_tissue|TCGA-Colorectal / Sample_Type by Project: Shred V9

SLC17A8 SLC17A7 ABCB11

9.19e-051722335d654dd030ed22a701e15c5f09002951d99a52e8
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_IT|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RASGEF1C SLC17A7 SLC9B2

9.67e-05175233c227fc5d1ccb69b82a96a6354913cafaf27d0eec
ToppCellCV-Mild-6|Mild / Virus stimulation, Condition and Cluster

BRAF ADGRL1 SLC9B2

9.67e-05175233c4d530dbb37942427c9cd0a1533faeb6a3a45381
ToppCellChildren_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

AP2A2 GPR155 IGF1

1.14e-041852338207f9eff113eed429e961748c6b17d672a13b33
ToppCellMonocytes-M2-like_CD16+_macrophages|Monocytes / Immune cells in Kidney/Urine in Lupus Nephritis

GPR155 TCHH IGF1

1.18e-0418723359e31c51183ed4c9a3d0792c8005ea3a12b28dfa
ToppCellHippocampus-Neuronal-Excitatory|Hippocampus / BrainAtlas - Mouse McCarroll V32

SLC17A7 RASGEF1A SRR

1.21e-041892334b90d181eb0a42814eeb23bc82e52fd3a12392a7
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC17A7 RASGEF1A ADGRL1

1.29e-04193233be28070c049e7cb68bcd54f582226eb2f5e4bc1c
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC17A7 RASGEF1A ADGRL1

1.29e-041932330c652ebe22ce5d2927599dd97ef1920547858395
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC17A7 RASGEF1A ADGRL1

1.29e-041932338689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCellHippocampus-Neuronal|Hippocampus / BrainAtlas - Mouse McCarroll V32

BRAF ADGRL1 TTLL11

1.31e-041942338aeb347b3024354c9505f4f0fddf0b843489dc6b
ToppCell367C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

AP2A2 GPR155 IGF1

1.33e-041952334008fa86b5166087a4b20f89ae07e1dfc87c855d
ToppCell(3)_MNP-(3)_Macrophage_MARCOneg|(3)_MNP / Lung cell shreds - cell class (v4) and cell subclass (v4)

AP2A2 GPR155 IGF1

1.33e-04195233e4b5e4b8832669fb4d1661ecd828b81e621d35c4
ToppCell367C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

AP2A2 GPR155 IGF1

1.35e-04196233e8c4eeb4b6c6d9bccca2adb942d4cfbaab39636c
ToppCelldistal-Hematologic-IGSF21+_Dendritic-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

AP2A2 GPR155 IGF1

1.37e-04197233e77c91f5a1f5a292eda41abf3b1e31180f2c61e1
ToppCellSepsis-ICU-NoSEP-Lymphocyte-B-Plasmablast|ICU-NoSEP / Disease, condition lineage and cell class

IGF1 SLC9B2 SPDYE3

1.37e-041972338f35f9741086a38f0e594dce0547b575946f52bb
ToppCelldistal-Hematologic-IGSF21+_Dendritic|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

AP2A2 GPR155 IGF1

1.37e-04197233a357ee2ba9100dfaeba9ecae8138a2776bb54b0b
ToppCelldistal-3-Hematologic-IGSF21+_Dendritic|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

AP2A2 GPR155 IGF1

1.37e-0419723352e9dc35dd8cc2605fa4894bb16bb5c6086faa76
ToppCellnormal_Lung-Myeloid_cells-mo-Mac|Myeloid_cells / Location, Cell class and cell subclass

AP2A2 GPR155 IGF1

1.39e-04198233fbd72ebaba73cc30e79dc8a8c3d46b6f863c1494
ToppCellBronchus_Control_(B.)-Stromal-TX-Mesothelial-2|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

SLC17A7 ALDH1L2 IGF1

1.41e-0419923360a653100aff31f7f96796ff2ec634798bfb4b0d
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Fezf2-Excitatory_Neuron.Slc17a7-Slc17a8.Fezf2-Slc17a8_(Layer_5,_Retrosplenial_cortex_(RSG)_and_Subiculum,_Tshz2+)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

SLC17A8 DRD5

6.25e-0472232e3f4d1df43cc41b0424f27485a00ddca9e905f95
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L6b-L6b_Hsd17b2|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SLC17A8 ABCB11

7.90e-048123220796e59cdeb398e7772f4356578d74a33405f71
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Fezf2|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

SLC17A8 DRD5

9.11e-0487232aaca22b97a42a1c4a10c5da708d1462101814386
ToppCelldroplet-Spleen-nan-21m-Hematologic-erythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGF1 FHDC1

9.53e-0489232e7d9498a1a3aa974fdd68b394c3eaff8e35c9727
ToppCellLPS-IL1RA-Epithelial_alveolar-Mes-Like-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RASGEF1C SLC17A8

1.27e-03103232eb9f008b5fb8a01df8ea4faf6e6aebc1a9db9bd3
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Pmch_(Lateral_hypothalamus_(LH))|Entopeduncular / BrainAtlas - Mouse McCarroll V32

IGF1 SLC9B2

1.40e-03108232ba83418023d9d296b0edd4c4e1832a33bc9b3b69
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Pmch_(Lateral_hypothalamus_(LH))--|Entopeduncular / BrainAtlas - Mouse McCarroll V32

IGF1 SLC9B2

1.40e-03108232a93a427ab16628c86db3bb17bfecf801f56ce270
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Pmch_(Lateral_hypothalamus_(LH))-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

IGF1 SLC9B2

1.40e-03108232673da75b24218557d01ee461a13c426040da74b9
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

SLC17A8 DRD5

1.58e-03115232207d464c09caf9be361daa56c83cd7da5cf9ce47
ToppCellBronchial-10x5prime-Stromal-Schwann-Schwann_nonmyelinating|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

GPR155 TTLL11

1.61e-03116232b0a3c109c5f20ab699e53bf8ab3903d102f5f315
ToppCellSubstantia_nigra-Neuronal-Excitatory|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

SLC17A7 DRD5

1.66e-031182329f1d744f46d79ff2ab7f168f54fdbd9f4640dddd
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_VISp_Col6a1_Fezf2|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SLC17A7 DRD5

1.78e-03122232e96aec5af0ed1d8f4cc99fde59dd6998bbc1acbd
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L5_PT-L5_PT_VISp_Chrna6|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ABCB11 DRD5

1.86e-03125232fac8a9bff83abb8976013ff7d2b4ce0b68fbb70a
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L6b-L6b_ALM_Olfr111_Spon1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

FHDC1 DRD5

1.92e-03127232cd69ba386796715e87674f8324d2acaad1d4d094
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligodendroglioma-2|TCGA-Brain / Sample_Type by Project: Shred V9

SLC17A8 ALDH1L2

1.92e-03127232018ffd9ff1913787cb0086a8581b399a121eaba1
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6|Striatum / BrainAtlas - Mouse McCarroll V32

SLC17A7 FHDC1

1.95e-03128232a876303c852db2af9418d1a1711d7c950805018a
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6-Excitatory_Neuron.Slc17a6.Oprk1_(Claustrum_cortex)-|Striatum / BrainAtlas - Mouse McCarroll V32

SLC17A7 FHDC1

1.95e-03128232388062f840fd04cb8087f27a9a78e7a192920e3e
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6-Excitatory_Neuron.Slc17a6.Oprk1_(Claustrum_cortex)|Striatum / BrainAtlas - Mouse McCarroll V32

SLC17A7 FHDC1

1.95e-031282327e3f5cea91af005f08d8e9340fb8630bf1c887c3
ToppCellfacs-Heart-RV-18m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HYDIN FHDC1

2.14e-031342320c63c8b3c748d29c59fcb27d03276ba4f6a0d6b2
ToppCellfacs-Heart-RV-18m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HYDIN FHDC1

2.14e-03134232d101e16cb87ff72c81324406fe7e3d70ed8f45df
ToppCellControl-Neu_1|World / 5 Neutrophil clusters in COVID-19 patients

ALDH1L2 SPDYE3

2.27e-03138232b7920c9a28d28220e7e4b30cd91ba13d0548eb76
ToppCellPND07-28-samps-Lymphocyte-T_cells-T_cells_2|PND07-28-samps / Age Group, Lineage, Cell class and subclass

SLC17A7 ABCB11

2.27e-03138232221a964e86d7d3406cdb7573899155fee8d33abd
ToppCellControl-Fibroblasts-Mesothelial_FB|Control / group, cell type (main and fine annotations)

ABCB11 RASGEF1A

2.30e-03139232e769beb031b262dd92c9605b07dbf3c29fb82520
ToppCellHealthy-CD4+_T_activated|World / disease group, cell group and cell class

GPR155 SPDYE3

2.33e-03140232407691970ec72a3afb45e431cf48814546b8acff
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RASGEF1C SLC17A8

2.36e-031412329a0f4bee2893da1b13ab89494e6159821d53538b
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Cpa6_Gpr88|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SLC17A7 SLC9B2

2.40e-0314223284742a7e35bab09ee1cca80cfe120b613d6aed6a
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sncg|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SLC17A8 IGF1

2.40e-03142232ed91d2ef4c346f7e1a5402846e2a34cee19c24d1
ToppCellsevere_COVID-19-B_cell|World / disease group, cell group and cell class (v2)

FHDC1 SLC9B2

2.43e-0314323228b0e168126a9fe60541dc12bfab385b7a0a2342
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Tac2_Tacstd2|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SLC17A8 ABCB11

2.43e-0314323224fd24846fbef049af669a57d42fcc18928d2b27
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Gkn1_Pcdh19|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

DRD5 SLC9B2

2.46e-03144232e8caeb6485f4c8f9a3384570dc69024c2bcc9ab0
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1|Hippocampus / BrainAtlas - Mouse McCarroll V32

SRR DRD5

2.46e-03144232e2a2f260f5ebaaef46248d199c407a15ce9d024a
ToppCellsevere_COVID-19-B_cell|severe_COVID-19 / disease group, cell group and cell class (v2)

FHDC1 SLC9B2

2.46e-03144232c7f696e55e2d959c58ec32640c71ef86ee25203c
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCB11 HYDIN

2.50e-0314523296712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-NP-L5_NP_VISp_Trhr_Met|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SLC17A8 DRD5

2.50e-031452328abbc781f5f69f039617c29a5589d7b6950c2c40
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SLC17A7 ADGRL1

2.56e-0314723255f4b3289094a1eab6d7a6c8f214ec7b031edfa8
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|368C / Donor, Lineage, Cell class and subclass (all cells)

GPR155 RASGEF1A

2.56e-031472323ed5b020ce1f1277917d79ef1f7da53fa474e8db
ToppCell10x5'-blood-Lymphocytic_B_plasma-Plasma_cells|blood / Manually curated celltypes from each tissue

ALDH1L2 IGF1

2.56e-0314723258089378fac1743ce99dc4f1bd7b5253a927f050
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-NP-L5_NP_ALM_Trhr_Nefl|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SLC17A8 DRD5

2.63e-03149232558a441804dbcd5b5f39a3b1933b48976711ff15
ToppCell343B-Lymphocytic-NK_cells-NK_cell_B2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

FHDC1 SPDYE3

2.63e-031492324034805c4eefb8bfb3a357273ccbdb77283ea4a5
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-NP-L5_NP_VISp_Trhr_Cpne7|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SLC17A8 DRD5

2.63e-031492328638b3819193d11411df58964069fec583f617f4
ToppCell10x5'-blood-Lymphocytic_B_plasma|blood / Manually curated celltypes from each tissue

ALDH1L2 IGF1

2.67e-031502326bab0a8bf78ed7de9e1b67ede7496488f80f4863
ToppCellFrontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

SLC17A7 DRD5

2.67e-031502329d5bbdca19da60e1a2121ef64ec8e1375a5dbf6d
ToppCellTCGA-Uterus-Primary_Tumor-Uterine_Carcinoma-Uterine_Carcinosarcoma|TCGA-Uterus / Sample_Type by Project: Shred V9

PPP4R3B FHDC1

2.70e-031512322810bfa01bd3016aeba29735eb4a9284792e8aac
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-NP|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SLC17A8 DRD5

2.74e-03152232b6a7453fbf9f898e4f222b215907c9a110baa2f6
ToppCellFrontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

TCHH DRD5

2.77e-03153232b37a1ecad389d2848b8ca4d287823e8048207420
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_12|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ALDH1L2 FHDC1

2.81e-031542321ad4152a3e4bf5912954235fe21c2447e99f3de7
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c08-GZMK-FOS_h|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

RASGEF1C TTLL11

2.81e-0315423289c9c9918af32f3952790b41f1471b2c80ffce2f
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_12|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ALDH1L2 FHDC1

2.81e-031542323c9d38709f507e91ec3bcc6184cbbfa9b1250128
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Dendritic-conventional_dendritic_cell-DC_c1-CLEC9A|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

ADGRL1 TCHH

2.85e-03155232d76a0f99ec35560d18820f9c92b69364ef2250e3
ToppCellControl-Epithelial-Ionocyte|Epithelial / Disease state, Lineage and Cell class

IGF1 OR9Q1

2.85e-031552324b9369b203a4d7071c56d3d8e6b450e9a0121c41
ToppCellfacs-Pancreas-Exocrine-24m-Epithelial-pancreatic_D_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGEF1A HYDIN

2.92e-03157232370f44047ef438b8f1124c2c2761c150c0d8c57f
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Lypd1_Gpr88|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RASGEF1C SLC17A7

2.92e-031572325aee90ad7aaa65fdabc23597451da5e48db8f4e6
ToppCellNS-moderate-d_07-13-Epithelial-FOXN4+|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

HYDIN TCHH

2.92e-03157232410c9d74a2085179cfb39853cb6d330fa98c9c1b
ToppCellStriatum-Neuronal-Inhibitory|Striatum / BrainAtlas - Mouse McCarroll V32

IGF1 DRD5

2.92e-03157232c41ff3fe9de7187575114febfe9bd8733366fb8a
ToppCellfacs-Marrow-KLS-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HYDIN FHDC1

2.95e-031582320edd9b005875f9a4f5446f5d5161f8ba63860793
ToppCell343B-Lymphocytic-NK_cells-NK_cell_D2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

AP2A2 SLC9B2

2.95e-0315823274aa4f75307575ac3b2b1aa9f727753692f88742
ToppCellfacs-Marrow-KLS-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HYDIN FHDC1

2.95e-031582329fd77ebdd1babf1c85a85d38d9a15858ab08bc84
ToppCellASK440-Immune-B_cell|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

RASGEF1A ALDH1L2

2.99e-03159232d31eb59c1b5948df721b829b9a7e806f27cbd41c
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Pld5|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RASGEF1C SLC17A7

2.99e-03159232a082e770fa757c4a1d3ed13d53f83297e36faf05
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HYDIN SLC9B2

2.99e-0315923200a157d033627d0e65c3fbd38d652c4cf56b47f6
ToppCellfacs-Marrow-Granulocytes-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGF1 FHDC1

3.03e-0316023256e6f4b82b5dc41c45f9d253c2db314a6f702b84
ToppCellLAM-Lymphoid-B-cell-2|LAM / Condition, Lineage and Cell class

ALDH1L2 IGF1

3.03e-031602320060c2b3304f411c682aa2ba20bcf80f346d2403
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Pericentral)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC17A8 ABCB11

3.03e-03160232c42bcc6c7d113f0db43febb088b75ca4ac7cb7a3
ToppCellfacs-Marrow-Granulocytes-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGF1 FHDC1

3.03e-03160232bb1b966fb9e801db15e67d03e49db4609d6f935a
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGEF1A IGF1

3.06e-0316123269f5e759c0925daa37e0177a9cc3154842906bf6
ToppCell343B-Lymphocytic-NK_cells-NK_cell_D2|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

AP2A2 SLC9B2

3.06e-0316123258381131e651744b5141b202f9d6063f55432db5
ToppCellICU-NoSEP-Lymphocyte-B-Plasmablast|ICU-NoSEP / Disease, Lineage and Cell Type

IGF1 SPDYE3

3.06e-031612328ca34d800551cb0f796293e6bfdcbf58509cc668
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

SLC17A7 HYDIN

3.06e-03161232ba7ce599b173cf81c8323e7c96dc3d57379f1ed6
ToppCellfacs-Marrow-Granulocytes-18m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGF1 FHDC1

3.06e-0316123260f433eab9d5531bdf6aa86b0265f20b866b904c
Drugamoxapine

SLC17A8 SLC17A7 DRD5

1.33e-0546233CID000002170
DrugValinomycin

SLC17A7 ABCB11

4.37e-0510232ctd:D014634
DrugParbendazole [14255-87-9]; Down 200; 16.2uM; MCF7; HT_HG-U133A

AP2A2 PPP4R3B ADGRL1 TCHH

4.40e-051992344357_DN
Drug1b9v

AP2A2 BRAF RASGEF1A

4.52e-0569233CID000444508
DrugN-(2-chloroethyl)-N-ethyl-2-bromobenzylamine

SLC17A8 SLC17A7 DRD5

4.52e-0569233CID000003172
Diseasetransient cerebral ischemia (biomarker_via_orthology)

SLC17A8 SLC17A7 IGF1

2.42e-04157233DOID:224 (biomarker_via_orthology)
Diseasecholestasis (biomarker_via_orthology)

ABCB11 IGF1

6.68e-0449232DOID:13580 (biomarker_via_orthology)
DiseaseIGFBP-3 measurement

RASGEF1A FHDC1

8.11e-0454232EFO_0004626

Protein segments in the cluster

PeptideGeneStartEntry
NFVRKTFFTLAFCDF

BRAF

236

P15056
NAFQGVFIFVFHCAL

ADGRL1

1086

O94910
FFNKGENCIAAGRLF

ALDH1L2

721

Q3SY69
QKANIYGFCFAFAQC

ABCB11

976

O95342
FARFVCKNNGVLFEN

AP2A2

706

O94973
FNADFQKVFAQLLGC

DRD5

361

P21918
FQIFRDFCTKFNKAV

FHDC1

446

Q9C0D6
RCAAQFFLFTFFGSI

OR9Q1

96

Q8NGQ5
ELQFFCAVFNFGQGF

GPR155

691

Q7Z3F1
RELVNFFKEFCAFSQ

PPP4R3B

331

Q5MIZ7
CEFNFINTGKFTFSF

HYDIN

4226

Q4G0P3
ALQFVCGDRGFYFNK

IGF1

61

P05019
GIFSNFLFRRCFKVK

TMEM126B

86

Q8IUX1
CFAGFNLKEKIFISF

SLC9B2

441

Q86UD5
QAFFETKQQGRCFYI

SLFN11

91

Q7Z7L1
FICQKFAANRVFGFA

SLC17A7

136

Q9P2U7
NLFFKCELFQKTGSF

SRR

41

Q9GZT4
CLQAFVEAFFFLAQR

TTLL11

706

Q8NHH1
FFIDVARECFNIGNF

RASGEF1A

296

Q8N9B8
SQIALFQKRRFQFFC

SPDYE3

501

A6NKU9
FFIDVARECFNIGNF

RASGEF1C

281

Q8N431
FNEFLLFIFKVAQAC

TCHH

71

Q07283
SNKFAANRVFGAAIF

SLC17A8

151

Q8NDX2