Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	actin binding	XIRP1 MAP1A MYO9B INPPL1 WHAMM AIF1L MICAL2 FHOD1 PPP1R18 PPP1R9B TAGLN MYO15A MYBPC2	6.85e-05	479	150	13	GO:0003779
GeneOntologyBiologicalProcess	protein-containing complex disassembly	SETX MAP1A APC2 PYM1 ARID1A SCAF4 PIK3R4 NFE2 MICAL2 CHMP3 PPP1R9B	8.43e-06	291	148	11	GO:0032984
HumanPheno	Aplasia/Hypoplasia of the corpus callosum	ADAT3 APC2 HECTD4 POMGNT1 ARID1A SLC1A4 AHDC1 COG8 SCAF4 SH3PXD2B ARID1B C2CD3 KMT2D CC2D2A GPSM2 KATNIP MED12 RAI1 SON	1.56e-05	772	46	19	HP:0007370
HumanPheno	Motor delay	ZNF142 INPPL1 APC2 HECTD4 POMGNT1 SLC1A4 AHDC1 CIC RYR1 SCAF4 SH3PXD2B ARID1B KMT2D ALMS1 ZNF592 PTPRQ NPAP1 GPSM2 MED12 CUX1 RAI1 SON	1.88e-05	1018	46	22	HP:0001270
HumanPheno	Thin corpus callosum	ADAT3 APC2 HECTD4 POMGNT1 ARID1A SLC1A4 AHDC1 COG8 SCAF4 SH3PXD2B ARID1B C2CD3 KMT2D MRAP CC2D2A GPSM2 KATNIP MED12 RAI1 SON	2.23e-05	868	46	20	HP:0033725
HumanPheno	Abnormal corpus callosum morphology	ADAT3 APC2 HECTD4 POMGNT1 ARID1A SLC1A4 AHDC1 COG8 SCAF4 SH3PXD2B ARID1B C2CD3 KMT2D MRAP CC2D2A GPSM2 KATNIP MED12 RAI1 SON	7.04e-05	937	46	20	HP:0001273
HumanPheno	Abnormal nasal bridge morphology	ADAT3 HYOU1 SCARF2 INPPL1 APC2 HECTD4 POMGNT1 ARID1A SLC1A4 AHDC1 RYR1 COG8 SH3PXD2B ARID1B KMT2D NPAP1 CC2D2A KATNIP MED12 RAI1 SON	8.15e-05	1029	46	21	HP:0000422
HumanPheno	Prominent forehead	ADAT3 INPPL1 APC2 HECTD4 RYR1 SH3PXD2B KMT2D MED12 RAI1 SON	8.31e-05	261	46	10	HP:0011220
HumanPheno	Abnormal facial shape	ADAT3 HYOU1 SCARF2 INPPL1 APC2 HECTD4 POMGNT1 CHD4 ARID1A SLC1A4 AHDC1 RYR1 SH3PXD2B ARID1B C2CD3 KMT2D ALMS1 CC2D2A KATNIP MED12 CUX1 RAI1 SON	1.07e-04	1221	46	23	HP:0001999
HumanPheno	Protruding ear	SCARF2 POMGNT1 SLC1A4 AHDC1 RYR1 SH3PXD2B KMT2D MED12 SON	1.17e-04	219	46	9	HP:0000411
HumanPheno	Infantile muscular hypotonia	ADAT3 ARID1A RYR1 COG8 ARID1B KMT2D MED12 RAI1 SON	1.17e-04	219	46	9	HP:0008947
HumanPheno	Partial agenesis of the corpus callosum	HECTD4 ARID1B C2CD3 GPSM2 MED12	1.54e-04	58	46	5	HP:0001338
HumanPheno	Severe sensorineural hearing impairment	KMT2D ALMS1 GPSM2	1.85e-04	13	46	3	HP:0008625
HumanPheno	Low-set ears	ADAT3 INPPL1 POMGNT1 CHD4 SLC1A4 AHDC1 RYR1 COG8 SH3PXD2B ARID1B C2CD3 KMT2D CC2D2A KATNIP MED12 CUX1 SON	1.88e-04	761	46	17	HP:0000369
HumanPheno	Severe hearing impairment	KMT2D ALMS1 GPSM2	2.34e-04	14	46	3	HP:0012714
HumanPheno	Cerebellar malformation	SETX APC2 POMGNT1 CHD4 ARID1A AHDC1 COG8 ARID1B C2CD3 KMT2D CC2D2A KATNIP SON	2.51e-04	487	46	13	HP:0002438
HumanPheno	Abnormal finger morphology	ADAT3 HYOU1 SCARF2 INPPL1 APC2 HECTD4 CHD4 ARID1A GDNF CIC RYR1 COG8 STK11 SH3PXD2B ARID1B C2CD3 KMT2D ALMS1 NPAP1 CC2D2A KATNIP MED12 RAI1 SON	2.68e-04	1385	46	24	HP:0001167
HumanPheno	Abnormal location of ears	ADAT3 SCARF2 INPPL1 POMGNT1 CHD4 SLC1A4 AHDC1 RYR1 COG8 SH3PXD2B ARID1B C2CD3 KMT2D CC2D2A KATNIP MED12 CUX1 RAI1 SON	2.72e-04	945	46	19	HP:0000357
HumanPheno	Enlarged posterior fossa	APC2 POMGNT1 ARID1A COG8 SH3PXD2B ARID1B C2CD3 CC2D2A	2.78e-04	193	46	8	HP:0005445
HumanPheno	Ventriculomegaly	ADAT3 APC2 POMGNT1 CHD4 ARID1A COG8 SH3PXD2B ARID1B C2CD3 KMT2D NPAP1 CC2D2A GPSM2 MED12 CUX1 RAI1 SON	2.99e-04	790	46	17	HP:0002119
HumanPheno	Abnormality of the palpebral fissures	ADAT3 SCARF2 INPPL1 APC2 HECTD4 CHD4 AHDC1 RYR1 COG8 SH3PXD2B ARID1B C2CD3 KMT2D NPAP1 MED12 CUX1 RAI1 SON	3.48e-04	880	46	18	HP:0008050
HumanPheno	Narrow face	HYOU1 APC2 HECTD4 RYR1 KMT2D MED12	3.71e-04	108	46	6	HP:0000275
HumanPheno	Abnormal response to endocrine stimulation test	ADAT3 KMT2D ALMS1 MRAP NPAP1 KATNIP MED12	3.84e-04	153	46	7	HP:0031073
HumanPheno	Ventricular septal defect	APC2 CHD4 ARID1A RYR1 SCAF4 SH3PXD2B ARID1B C2CD3 KMT2D MED12 CUX1 RAI1 SON	3.97e-04	510	46	13	HP:0001629
HumanPheno	Prominent eyelashes	ARID1A ARID1B KMT2D	4.29e-04	17	46	3	HP:0011231
HumanPheno	Abnormal endocrine physiology	ADAT3 KMT2D ALMS1 MRAP NPAP1 KATNIP MED12	4.33e-04	156	46	7	HP:0031072
Domain	LRRC37AB_C	LRRC37A3 LRRC37A2 LRRC37A	1.94e-06	4	148	3	IPR029423
Domain	LRRC37AB_C	LRRC37A3 LRRC37A2 LRRC37A	1.94e-06	4	148	3	PF14914
Domain	LRRC37_N	LRRC37A3 LRRC37A2 LRRC37A	1.94e-06	4	148	3	IPR032754
Domain	LRRC37	LRRC37A3 LRRC37A2 LRRC37A	1.94e-06	4	148	3	PF15779
Domain	LRRC37A/B-like	LRRC37A3 LRRC37A2 LRRC37A	1.94e-06	4	148	3	IPR015753
Domain	GOLGA6L	GOLGA6L4 GOLGA6L10 GOLGA6L19	9.58e-06	6	148	3	IPR026737
Domain	Ubiquitin-rel_dom	MYO9B SF3A1 FRMPD1 GRB7 PPP1R13B PCGF6 SHARPIN ARHGAP20 RGL2	1.63e-05	184	148	9	IPR029071
Domain	BAF250/Osa	ARID1A ARID1B	6.24e-05	2	148	2	IPR021906
Domain	BAF250_C	ARID1A ARID1B	6.24e-05	2	148	2	IPR033388
Domain	BAF250_C	ARID1A ARID1B	6.24e-05	2	148	2	PF12031
Domain	RA	MYO9B GRB7 ARHGAP20 RGL2	1.83e-04	36	148	4	PF00788
Domain	BAT2_N	PRRC2C PRRC2A	1.86e-04	3	148	2	PF07001
Domain	BAT2_N	PRRC2C PRRC2A	1.86e-04	3	148	2	IPR009738
Domain	PRRC2	PRRC2C PRRC2A	1.86e-04	3	148	2	IPR033184
Domain	RA	MYO9B GRB7 ARHGAP20 RGL2	2.04e-04	37	148	4	PS50200
Domain	RA_dom	MYO9B GRB7 ARHGAP20 RGL2	2.77e-04	40	148	4	IPR000159
Domain	ARM-like	SETX APC2 ARID1A PIK3R4 ARID1B MROH1 FHOD1 PPP6R2 MED12	3.08e-04	270	148	9	IPR011989
Domain	GOLGA2L5	GOLGA6L4 GOLGA6L10 GOLGA6L19	3.65e-04	18	148	3	PF15070
Domain	Golgin_A	GOLGA6L4 GOLGA6L10 GOLGA6L19	3.65e-04	18	148	3	IPR024858
Domain	Homeobox_CS	GSX1 UNCX RAX ZFHX4 ZFHX2 ZFHX3 CUX1	7.13e-04	186	148	7	IPR017970
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	MYO9B CDK12 INPPL1 HECTD4 POMGNT1 RAPGEF1 BCL9 ARID1A POM121C AHDC1 CIC RYR1 EPS15L1 SH3PXD2B TNRC18 C2CD3 KMT2D MROH1 ADAMTS7 ZNF592 STRN4 PALM TNKS1BP1 TAGLN RGL2 MED12 RAI1 RAD9A PPP1R16A	1.79e-14	1105	157	29	35748872
Pubmed	Interaction network of human early embryonic transcription factors.	HYOU1 RAD54L2 BCL9 ARID1A POM121C AHDC1 PCGF6 ARID1B TNRC18 KMT2D ALMS1 ZFHX4 EHMT2 ZNF746 ZFHX3 MED12 RAI1	5.41e-13	351	157	17	38297188
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	CDK12 SF3A1 TBC1D2 CHD4 ZC3H18 GPATCH8 BCL9 CIC SCAF4 OTUD7B TBC1D10B EPS15L1 KMT2D ZNF592 FHOD1 CCAR1 PPP1R18 TNKS1BP1 MAPK8 PARD3 PRRC2A SON	7.57e-12	774	157	22	15302935
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	CHD4 BCL9 ARID1A AHDC1 CIC TAF6L ARID1B TNRC18 KMT2D EHMT2 MEPCE MED12 CUX1 RAI1	2.42e-11	268	157	14	33640491
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	MAP1A TAF1C MBD1 MMP21 CHD4 ZC3H18 GIGYF1 ARID1A POM121C TAF6L TBC1D10B ARID1B ALMS1 ZFHX4 EHMT2 ZNF592 TNRC6A MEPCE ZFHX3 TIGD5 PARD3 RAI1 SEZ6L SON	2.43e-10	1116	157	24	31753913
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	EPS15 SETX CDK12 TAF1C MBD1 WHAMM PYM1 AIF1L GPATCH8 AHDC1 CIC SCAF4 TAF6L EHMT2 ZNF592 CRACDL TNRC6A STRN4 CCAR1 PPP1R18 AATF ZFHX3 PARD3 PRRC2A FHIP1A MED12 SON	7.82e-10	1497	157	27	31527615
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	JCAD SETX TEX2 INPPL1 MBD1 NCKIPSD GIGYF1 CIC PIK3R4 TBC1D10B SH3PXD2B C2CD3 MAST4 ALMS1 CASKIN2 PRRC2C MEPCE TNKS1BP1 PARD3 RGL2	2.39e-09	861	157	20	36931259
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	CDK12 PPP1R13B ARID1A SCAF4 EPS15L1 SH3PXD2B ARID1B KMT2D ALMS1 PRRC2C STRN4 TNKS1BP1 PARD3 PRRC2A MED12 CUX1	4.57e-09	549	157	16	38280479
Pubmed	Human transcription factor protein interaction networks.	PPP1R13B ZC3H18 GIGYF1 GPATCH8 RAD54L2 BCL9 ARID1A POM121C CIC SCAF4 TAF6L PCGF6 ARID1B KMT2D ALMS1 ZFHX4 EHMT2 ZNF592 PRRC2C ZNF746 TNRC6A CCAR1 ZFHX3 PRRC2A CUX1	6.61e-09	1429	157	25	35140242
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	JCAD EPS15 MAP1A INPPL1 APC2 RAD54L2 BCL9 POM121C CIC OTUD7B TGFB1I1 TNRC18 FHIP1A SON	1.11e-08	430	157	14	35044719
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	JCAD TAF1C MBD1 APC2 HECTD4 RTL10 WHAMM CHD4 RAD54L2 ARID1A BFSP1 PIK3R4 EPS15L1 EHMT2 ZNF592 MICAL2 SHARPIN CHMP3 CCAR1 GPSM2 PRRC2A CUX1 SEZ6L	1.88e-08	1285	157	23	35914814
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	SETX SF3A1 TAF1C MBD1 CHD4 ZC3H18 GPATCH8 ARID1A POM121C AHDC1 CIC SCAF4 TAF6L PCGF6 KMT2D EHMT2 CCAR1 AATF TIGD5 CUX1 RAI1 SON CREB3L2	2.14e-08	1294	157	23	30804502
Pubmed	NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.	CHD4 ZC3H18 GPATCH8 ZFHX4 EHMT2 ZNF592 ZFHX3 RAI1	2.38e-08	103	157	8	32744500
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	SETX HYOU1 UNCX SF3A1 CHD4 RAD54L2 BCL9 ARID1A AHDC1 CIC SCAF4 PRAM1 ARID1B TNRC18 KMT2D PRRC2C CCAR1 PRRC2A MED12 CUX1 RAI1	2.93e-08	1103	157	21	34189442
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	EPS15 MAP1A CDK12 SF3A1 PYM1 CHD4 POM121C CIC SCAF4 EPS15L1 ALMS1 PRRC2C FHOD1 MEPCE PPP1R9B TNKS1BP1 PPP6R2 PRRC2A SON	5.07e-08	934	157	19	33916271
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	JCAD HYOU1 PPP1R13B TNS2 ARID1A CIC TBC1D10B ARID1B C2CD3 KMT2D PPP2R5B CASKIN2 TNRC6A PPP1R18 PALM PPP1R9B AATF MAPK8 PPP6R2 PRRC2A	6.30e-08	1049	157	20	27880917
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	EPS15 CHD4 CIC KMT2D ALMS1 ZFHX4 EHMT2 ZNF592 TNRC6A ZFHX3 TNKS1BP1 MED12 CUX1	6.45e-08	418	157	13	34709266
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	MAP1A TEX2 BCAS1 SLC1A4 EPS15L1 SRGAP3 PRRT3 STRN4 PALM TNKS1BP1 PPP6R2 PRRC2A	6.72e-08	347	157	12	17114649
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	BDP1 SETX MAP1A MYO9B INPPL1 PPP1R13B ZC3H18 RAD54L2 ARID1A CIC ALMS1 PRRC2C TNRC6A TNKS1BP1 PPP6R2	8.10e-08	588	157	15	38580884
Pubmed	Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.	CDK12 BCL9 ARID1A CIC ARID1B KMT2D CUX1	1.04e-07	83	157	7	28794006
Pubmed	Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.	MAP1A TBC1D2 GIGYF1 C2CD3 KMT2D ALMS1 ZNF592 ZNF746 TNRC6A	1.72e-07	184	157	9	32908313
Pubmed	Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.	CDK12 GIGYF1 GPATCH8 BCL9 ARID1A POM121C AHDC1 CIC ARID1B KMT2D PRRC2C TNRC6A RAI1	1.80e-07	457	157	13	32344865
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	SETX PYM1 ZC3H18 ARID1A AHDC1 KMT2D ALMS1 EHMT2 ZNF592 PRRC2C TNRC6A CCAR1 TNKS1BP1	2.41e-07	469	157	13	27634302
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	SETX CDK12 SF3A1 CHD4 ZC3H18 ARID1A CIC SCAF4 PRAM1 EPS15L1 ARID1B PRRC2C CCAR1 AATF PRRC2A CUX1 RAI1 SON	3.52e-07	954	157	18	36373674
Pubmed	Primate segmental duplication creates novel promoters for the LRRC37 gene family within the 17q21.31 inversion polymorphism region.	LRRC37A3 LRRC37A2 LRRC37A	3.60e-07	4	157	3	22419166
Pubmed	Behavioral abnormalities observed in Zfhx2-deficient mice.	ZFHX4 ZFHX2 ZFHX3	3.60e-07	4	157	3	23300874
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	MYO9B TBC1D2 CHD4 ARID1A AHDC1 SH3PXD2B TNRC18 PRRC2C TNKS1BP1 PRRC2A SON	3.69e-07	332	157	11	37433992
Pubmed	Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.	HYOU1 SF3A1 POMGNT1 PPP1R13B TNS2 GDNF PPP2R5B STRN4 PPP1R18 PPP1R9B PARD3 PPP6R2 CUX1 PPP1R16A	3.75e-07	573	157	14	28330616
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	EPS15 APC2 HECTD4 CHD4 BCL9 EPS15L1 SH3PXD2B EHMT2 SRGAP3 PRRC2C STRN4 CCAR1 PPP1R9B PARD3 PPP6R2 PRRC2A CUX1 RAI1	4.03e-07	963	157	18	28671696
Pubmed	The SH3 domain of Crk binds specifically to a conserved proline-rich motif in Eps15 and Eps15R.	EPS15 RAPGEF1 EPS15L1	8.97e-07	5	157	3	7797522
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SETX CDK12 TEX2 HECTD4 ARID1B MAST4 ZNF592 CASKIN2 TNRC6A PALM TNKS1BP1 ARHGAP20 RAI1	9.34e-07	529	157	13	14621295
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	JCAD NCKIPSD PPP1R13B GIGYF1 ARID1A ARID1B ALMS1 TNRC6A STRN4 PPP1R9B PARD3 PPP6R2	9.73e-07	446	157	12	24255178
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	JCAD ZNF142 LRRC37A3 BCL9 ARID1A POM121C CIC RYR1 ARID1B KMT2D AATF TIGD5 CUX1 RAI1	1.34e-06	638	157	14	31182584
Pubmed	The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.	SF3A1 MBD1 CHD4 RAD54L2 CIC PCGF6 ZFHX4 EHMT2 ZNF592 CCAR1 ZFHX3 CUX1 SON	2.72e-06	583	157	13	29844126
Pubmed	Functional proteomics mapping of a human signaling pathway.	EPS15 CDK12 MBD1 PPP1R13B PPP1R15A TGFB1I1 ARID1B KMT2D MAST4 ZNF592 CHMP3 PPP1R9B SON	3.15e-06	591	157	13	15231748
Pubmed	cDNAs with long CAG trinucleotide repeats from human brain.	TNRC18 KMT2D TNRC6A MED12	3.31e-06	23	157	4	9225980
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	HYOU1 PPP1R13B GIGYF1 ARID1A POM121C ALMS1 CASKIN2 TNRC6A PARD3	3.37e-06	263	157	9	34702444
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	HYOU1 MAP1A TAF1C PYM1 PCGF6 SH3PXD2B PRRC2C TNRC6A CCAR1 PPP1R9B AATF TAGLN PRRC2A SON	5.73e-06	724	157	14	36232890
Pubmed	Disruption of SorCS2 reveals differences in the regulation of stereociliary bundle formation between hair cell types in the inner ear.	NPPC ALMS1 GPSM2	7.43e-06	9	157	3	28346477
Pubmed	TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.	CHD4 ARID1A ARID1B KMT2D CCAR1 ZFHX3 MED12 SON	7.69e-06	220	157	8	35785414
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	HYOU1 UNCX MMP21 CHD4 RAD54L2 ARID1A STK11 TNRC18 C2CD3 PRRC2C STRN4 CCAR1 PALM CC2D2A PPP1R9B AATF ITIH6 CUX1 RAI1 MYBPC2	8.51e-06	1442	157	20	35575683
Pubmed	RNF138 inhibits late inflammatory gene transcription through degradation of SMARCC1 of the SWI/SNF complex.	CHD4 ARID1A ARID1B CUX1	8.69e-06	29	157	4	36800290
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	SETX MAP1A CDK12 SF3A1 HECTD4 CHD4 ZC3H18 GPATCH8 ARID1A AHDC1 SCAF4 TBC1D10B ARID1B CCAR1 TNKS1BP1 MED12 SON	8.71e-06	1082	157	17	38697112
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	HYOU1 SF3A1 CHD4 ZC3H18 ARID1A PRRC2C CCAR1 AATF TNKS1BP1 PRRC2A MED12 RAI1 SON	9.20e-06	653	157	13	22586326
Pubmed	Evolutionary dynamism of the primate LRRC37 gene family.	LRRC37A3 LRRC37A2 LRRC37A	1.06e-05	10	157	3	23064749
Pubmed	A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.	MAP1A CDK12 ARID1A CIC SCAF4 SH3PXD2B ARID1B FHOD1 TAGLN MED12 CUX1	1.08e-05	472	157	11	38943005
Pubmed	A human MAP kinase interactome.	ZNF142 SETX MAP1A PPP1R13B RAPGEF1 POM121C CIC FHOD1 TNRC6A RGL2 CUX1	1.42e-05	486	157	11	20936779
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	JCAD NCKIPSD ARID1A ARID1B TNRC18 KMT2D ZFHX4 AATF MYO15A CUX1	1.45e-05	398	157	10	35016035
Pubmed	Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome.	CIC PCGF6 ALMS1 PRRC2C TNRC6A MEPCE PRRC2A MED12	1.53e-05	242	157	8	34011540
Pubmed	SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.	CDK12 CHD4 ZC3H18 SCAF4 TBC1D10B KMT2D PRRC2C CCAR1	1.99e-05	251	157	8	31076518
Pubmed	Frmpd1 Facilitates Trafficking of G-Protein Transducin and Modulates Synaptic Function in Rod Photoreceptors of Mammalian Retina.	FRMPD1 GPSM2	2.02e-05	2	157	2	36180221
Pubmed	Structural and biochemical characterization of the interaction between LGN and Frmpd1.	FRMPD1 GPSM2	2.02e-05	2	157	2	23318951
Pubmed	Dissecting the role of SWI/SNF component ARID1B in steady-state hematopoiesis.	ARID1A ARID1B	2.02e-05	2	157	2	37611161
Pubmed	Subunits of ARID1 serve as novel biomarkers for the sensitivity to immune checkpoint inhibitors and prognosis of advanced non-small cell lung cancer.	ARID1A ARID1B	2.02e-05	2	157	2	32791957
Pubmed	The mouse ZFH-4 protein contains four homeodomains and twenty-two zinc fingers.	ZFHX4 ZFHX3	2.02e-05	2	157	2	10873665
Pubmed	Chromatin accessibility underlies synthetic lethality of SWI/SNF subunits in ARID1A-mutant cancers.	ARID1A ARID1B	2.02e-05	2	157	2	28967863
Pubmed	Dual ARID1A/ARID1B loss leads to rapid carcinogenesis and disruptive redistribution of BAF complexes.	ARID1A ARID1B	2.02e-05	2	157	2	34386776
Pubmed	Integrated genomic analyses identify ARID1A and ARID1B alterations in the childhood cancer neuroblastoma.	ARID1A ARID1B	2.02e-05	2	157	2	23202128
Pubmed	ARID1 proteins: from transcriptional and post-translational regulation to carcinogenesis and potential therapeutics.	ARID1A ARID1B	2.02e-05	2	157	2	33890484
Pubmed	CDK12 alterations and ARID1A mutations are predictors of poor prognosis and therapeutic targets in high-grade salivary gland carcinoma: analysis of the National Genomic Profiling Database.	CDK12 ARID1A	2.02e-05	2	157	2	37357968
Pubmed	ARID1B is a specific vulnerability in ARID1A-mutant cancers.	ARID1A ARID1B	2.02e-05	2	157	2	24562383
Pubmed	ARID1B as a Potential Therapeutic Target for ARID1A-Mutant Ovarian Clear Cell Carcinoma.	ARID1A ARID1B	2.02e-05	2	157	2	29890703
Pubmed	JNK-mediated turnover and stabilization of the transcription factor p45/NF-E2 during differentiation of murine erythroleukemia cells.	NFE2 MAPK8	2.02e-05	2	157	2	19966288
Pubmed	SWI/SNF factors required for cellular resistance to DNA damage include ARID1A and ARID1B and show interdependent protein stability.	ARID1A ARID1B	2.02e-05	2	157	2	24788099
Pubmed	Establishment and characterization of VOA1066 cells: An undifferentiated endometrial carcinoma cell line.	ARID1A ARID1B	2.02e-05	2	157	2	33052929
Pubmed	Dual role for the methyltransferase G9a in the maintenance of beta-globin gene transcription in adult erythroid cells.	EHMT2 NFE2	2.02e-05	2	157	2	19822740
Pubmed	Par3 controls epithelial spindle orientation by aPKC-mediated phosphorylation of apical Pins.	GPSM2 PARD3	2.02e-05	2	157	2	20933426
Pubmed	Concurrent ARID1A and ARID1B inactivation in endometrial and ovarian dedifferentiated carcinomas.	ARID1A ARID1B	2.02e-05	2	157	2	27562491
Pubmed	CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.	SF3A1 CHD4 ZC3H18 ARID1A ZFHX4 ZNF592 PRRC2C CCAR1 AATF ZFHX3 CUX1 RAI1	2.13e-05	605	157	12	28977666
Pubmed	Mutations of the Transcriptional Corepressor ZMYM2 Cause Syndromic Urinary Tract Malformations.	SETX CHD4 RAD54L2 PCGF6 EHMT2 ZNF746	2.32e-05	125	157	6	32891193
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	HYOU1 MAP1A NCKIPSD BCAS1 ARID1A SLC1A4 PIK3R4 EPS15L1 SRGAP3 MICAL2 PRRC2C CRACDL STRN4 PPP1R18 PALM PPP1R9B TNKS1BP1 PPP6R2 PRRC2A	2.65e-05	1431	157	19	37142655
Pubmed	Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus.	GSX1 RAX CIC TGFB1I1 ZFHX4 ZFHX2 ZFHX3 FBLIM1	2.78e-05	263	157	8	20932939
Pubmed	A trans-eQTL network regulates osteoclast multinucleation and bone mass.	EPS15 SLC1A4 TGFB1I1	3.17e-05	14	157	3	32553114
Pubmed	Interaction proteome of human Hippo signaling: modular control of the co-activator YAP1.	HYOU1 PPP1R13B ZC3H18 GPATCH8 STRN4 PPP1R18 PPP1R9B PARD3	3.35e-05	270	157	8	24366813
Pubmed	Genome-wide CRISPR screens using isogenic cells reveal vulnerabilities conferred by loss of tumor suppressors.	CHD4 ARID1A STK11 FHOD1 SHARPIN CCAR1 PALM SPOCD1 SON	3.99e-05	359	157	9	35559673
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	SETX HYOU1 CDK12 GRB7 GIGYF1 RAD54L2 PIK3R4 TBC1D10B CASKIN2 PRRC2C CCAR1 PPP6R2	4.26e-05	650	157	12	38777146
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	BDP1 EPS15 SLC22A23 FRMPD1 HECTD4 ARID1A AHDC1 EPS15L1 TNRC18 MICAL2 CCAR1 ZFHX2 PPP1R9B KATNIP ZFHX3 PARD3 CUX1 RAI1 CREB3L2	4.53e-05	1489	157	19	28611215
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	MAP1A TEX2 INPPL1 MAST4 ALMS1 TNRC6A TNKS1BP1	4.87e-05	209	157	7	36779422
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	JCAD EPS15 INPPL1 PPP1R13B TBC1D10B EPS15L1 SH3PXD2B CASKIN2 PPP1R18 TNKS1BP1 PARD3	5.59e-05	565	157	11	25468996
Pubmed	Yap- and Cdc42-dependent nephrogenesis and morphogenesis during mouse kidney development.	UNCX GDNF PARD3 HES5	5.63e-05	46	157	4	23555292
Pubmed	Charting the landscape of tandem BRCT domain-mediated protein interactions.	CDK12 SF3A1 MBD1 ARID1A SCAF4 ALMS1 STRN4 MEPCE CCAR1 PPP1R18 PPP1R9B CUX1	5.70e-05	670	157	12	22990118
Pubmed	Identification of a polymorphic, neuron-specific chromatin remodeling complex.	ARID1A ARID1B SRGAP3	5.86e-05	17	157	3	12368262
Pubmed	Molecular Insights into the Fungus-Specific Serine/Threonine Protein Phosphatase Z1 in Candida albicans.	PPP1R15A PPP1R9B	6.06e-05	3	157	2	27578752
Pubmed	Dynamics of expression of ARID1A and ARID1B subunits in mouse embryos and in cells during the cell cycle.	ARID1A ARID1B	6.06e-05	3	157	2	21647563
Pubmed	POM121 inhibits the macrophage inflammatory response by impacting NF-κB P65 nuclear accumulation.	POM121C POM121B	6.06e-05	3	157	2	30802453
Pubmed	Nucleoporin POM121 signals TFEB-mediated autophagy via activation of SIGMAR1/sigma-1 receptor chaperone by pridopidine.	POM121C POM121B	6.06e-05	3	157	2	35507432
Pubmed	Searching for NIDDM susceptibility genes: studies of genes with triplet repeats expressed in skeletal muscle.	TNRC6A MED12	6.06e-05	3	157	2	8781769
Pubmed	Single-cell Sequencing Reveals Variants in ARID1A, GPRC5A and MLL2 Driving Self-renewal of Human Bladder Cancer Stem Cells.	ARID1A KMT2D	6.06e-05	3	157	2	27387124
Pubmed	A single motif responsible for ubiquitin recognition and monoubiquitination in endocytic proteins.	EPS15 EPS15L1	6.06e-05	3	157	2	11919637
Pubmed	Differential patterns of expression of Eps15 and Eps15R during mouse embryogenesis.	EPS15 EPS15L1	6.06e-05	3	157	2	10906484
Pubmed	Replication of genetic variation in the MYO9B gene in Crohn's disease.	MYO9B PARD3	6.06e-05	3	157	2	21515326
Pubmed	Intestinal barrier gene variants may not explain the increased levels of antigliadin antibodies, suggesting other mechanisms than altered permeability.	MYO9B PARD3	6.06e-05	3	157	2	20096742
Pubmed	ARID1A, ARID1B, and ARID2 Mutations Serve as Potential Biomarkers for Immune Checkpoint Blockade in Patients With Non-Small Cell Lung Cancer.	ARID1A ARID1B	6.06e-05	3	157	2	34512623
Pubmed	Loss of ARID1B and SMARCB1 expression are specific for the diagnosis of dedifferentiated/undifferentiated carcinoma in tumours of the upper gynaecological tract and cervix.	ARID1A ARID1B	6.06e-05	3	157	2	33432679
Pubmed	Smooth muscle-specific LKB1 deletion exaggerates angiotensin II-induced abdominal aortic aneurysm in mice.	STK11 TAGLN	6.06e-05	3	157	2	30935996
Pubmed	CCAAT displacement protein/cut homolog recruits G9a histone lysine methyltransferase to repress transcription.	EHMT2 CUX1	6.06e-05	3	157	2	15269344
Pubmed	TNPO1-mediated nuclear import of ARID1B promotes tumor growth in ARID1A-deficient gynecologic cancer.	ARID1A ARID1B	6.06e-05	3	157	2	34044070
Pubmed	Genome-Wide Transcriptional Regulation Mediated by Biochemically Distinct SWI/SNF Complexes.	ARID1A ARID1B	6.06e-05	3	157	2	26716708
Pubmed	Palmitate induces SHIP2 expression via the ceramide-mediated activation of NF-κB, and JNK in skeletal muscle cells.	INPPL1 MAPK8	6.06e-05	3	157	2	24924631
Pubmed	Mutations affecting components of the SWI/SNF complex cause Coffin-Siris syndrome.	ARID1A ARID1B	6.06e-05	3	157	2	22426308
Interaction	TLE3 interactions	CDK12 GPATCH8 RAD54L2 BCL9 ARID1A AHDC1 CIC SCAF4 ARID1B TNRC18 KMT2D TNRC6A CCAR1 ZFHX3 TNKS1BP1 CUX1 SON	3.89e-09	376	152	17	int:TLE3
Interaction	TOP3B interactions	HYOU1 MYO9B CDK12 INPPL1 HECTD4 POMGNT1 RAPGEF1 PYM1 BCL9 ARID1A POM121C AHDC1 CIC RYR1 EPS15L1 SH3PXD2B TNRC18 C2CD3 KMT2D MROH1 ADAMTS7 ZNF592 STRN4 PALM PPP1R9B TNKS1BP1 TAGLN RGL2 PRRC2A MED12 RAI1 RAD9A PPP1R16A	1.15e-08	1470	152	33	int:TOP3B
Interaction	TBXT interactions	BCL9 ARID1A CIC ARID1B KMT2D ZFHX4 EHMT2 ZNF746 CCAR1 CUX1	1.82e-08	116	152	10	int:TBXT
Interaction	FEV interactions	GPATCH8 RAD54L2 BCL9 ARID1A CIC ARID1B KMT2D ZFHX4 EHMT2 ZNF746 ZFHX3 CUX1	4.67e-08	203	152	12	int:FEV
Interaction	EGR2 interactions	RAD54L2 BCL9 ARID1A AHDC1 PCGF6 ARID1B TNRC18 KMT2D ZFHX4 ZNF746 ZFHX3	7.32e-08	171	152	11	int:EGR2
Interaction	VASP interactions	EPS15 XIRP1 MAP1A INPPL1 PPP1R13B TBC1D10B ALMS1 FHOD1 TNRC6A PPP1R9B TNKS1BP1 FBLIM1 PARD3	3.73e-07	294	152	13	int:VASP
Interaction	AR interactions	INPPL1 HECTD4 GRB7 CHD4 RAD54L2 BCL9 ARID1A AHDC1 CIC TGFB1I1 TAF6L ARID1B TNRC18 KMT2D EHMT2 MEPCE CCAR1 AATF ZFHX3 MED12 CUX1 RAI1 SON RAD9A	4.12e-07	992	152	24	int:AR
Interaction	CRX interactions	TNS2 BCL9 ARID1A PCGF6 ARID1B TNRC18 KMT2D ZFHX4 EHMT2 ZFHX3 MED12 RAI1	5.30e-07	254	152	12	int:CRX
Interaction	NUP43 interactions	SETX CDK12 ZC3H18 CCDC168 GPATCH8 RAD54L2 ARID1A POM121C AHDC1 ARID1B KMT2D ZNF592 PRRC2C AATF ZFHX3 PPP6R2 MED12 SON	1.19e-06	625	152	18	int:NUP43
Interaction	LHX3 interactions	AIF1L BCL9 ARID1A CIC PCGF6 ARID1B KMT2D ZFHX4 EHMT2 CUX1	1.45e-06	185	152	10	int:LHX3
Interaction	WWTR1 interactions	CDK12 PPP1R13B ARID1A EPS15L1 SH3PXD2B ARID1B KMT2D ALMS1 PRRC2C STRN4 TNKS1BP1 PARD3 PRRC2A CUX1	3.96e-06	422	152	14	int:WWTR1
Interaction	NUP35 interactions	GSX1 CDK12 GIGYF1 GPATCH8 BCL9 ARID1A POM121C AHDC1 CIC ARID1B KMT2D PRRC2C TNRC6A RAI1	4.18e-06	424	152	14	int:NUP35
Interaction	PAX7 interactions	BCL9 ARID1A CIC ARID1B KMT2D ZFHX4 ZNF746 ZFHX3	4.58e-06	124	152	8	int:PAX7
Interaction	PAX9 interactions	BCL9 ARID1A CIC ARID1B KMT2D ZFHX4 EHMT2 ZFHX3	6.50e-06	130	152	8	int:PAX9
Interaction	SNRNP40 interactions	SETX CDK12 SF3A1 ZC3H18 GPATCH8 BCL9 ARID1A POM121C AHDC1 SCAF4 ARID1B MEPCE CCAR1 AATF ZFHX3 MED12 SON	6.60e-06	637	152	17	int:SNRNP40
Interaction	TLX1 interactions	BCL9 ARID1A CIC ARID1B KMT2D ZFHX4 EHMT2 ZFHX3 CUX1	7.40e-06	175	152	9	int:TLX1
Interaction	YWHAH interactions	JCAD SETX TEX2 INPPL1 NCKIPSD HECTD4 TNS2 GIGYF1 CIC PIK3R4 TBC1D10B SH3PXD2B C2CD3 MAST4 ALMS1 CASKIN2 PRRC2C MEPCE CC2D2A PPP1R9B TNKS1BP1 PARD3 RGL2	8.76e-06	1102	152	23	int:YWHAH
Interaction	DPRX interactions	RAD54L2 ZFHX4 EHMT2 ZFHX3	8.77e-06	18	152	4	int:DPRX
Interaction	SOX9 interactions	BCL9 ARID1A CIC ARID1B KMT2D MED12 CUX1	8.80e-06	97	152	7	int:SOX9
Interaction	ALG13 interactions	GPATCH8 BCL9 ARID1A ARID1B KMT2D PRRC2C TNRC6A CCAR1 PRRC2A	1.06e-05	183	152	9	int:ALG13
Interaction	LHX2 interactions	BCL9 ARID1A CIC ARID1B KMT2D ZFHX4 EHMT2 ZFHX3 CUX1	1.06e-05	183	152	9	int:LHX2
Interaction	TLX2 interactions	BCL9 ARID1A CIC ARID1B KMT2D EHMT2 ZFHX3 CUX1	1.24e-05	142	152	8	int:TLX2
Interaction	GATA3 interactions	BCL9 ARID1A CIC SCAF4 ARID1B KMT2D ZFHX4 ZNF746 CCAR1	1.26e-05	187	152	9	int:GATA3
Interaction	TLX3 interactions	BCL9 ARID1A CIC TGFB1I1 ARID1B KMT2D ZFHX4 EHMT2 ZFHX3 ITIH6 CUX1	1.35e-05	291	152	11	int:TLX3
Interaction	SP7 interactions	GPATCH8 BCL9 ARID1A CIC SCAF4 ARID1B KMT2D ZFHX4 EHMT2 CCAR1 CUX1	2.02e-05	304	152	11	int:SP7
Interaction	GATA2 interactions	BCL9 ARID1A CIC ARID1B KMT2D ZFHX4 EHMT2 ZFHX3 CUX1	2.07e-05	199	152	9	int:GATA2
Interaction	PAX6 interactions	BCL9 ARID1A RAX CIC PCGF6 ARID1B KMT2D ZFHX4 EHMT2 ZNF746 ZFHX3 CUX1	2.24e-05	366	152	12	int:PAX6
Interaction	TBR1 interactions	BCL9 ARID1A CIC ARID1B KMT2D ZFHX4 ZFHX3	2.39e-05	113	152	7	int:TBR1
Interaction	YAP1 interactions	JCAD HYOU1 CDK12 SF3A1 APC2 CHD4 ARID1A SCAF4 OTUD7B TGFB1I1 EPS15L1 ARID1B TNRC18 KMT2D NFE2 PRRC2C SHARPIN TNKS1BP1 PARD3 PRRC2A MED12 CUX1	2.52e-05	1095	152	22	int:YAP1
Interaction	EYA2 interactions	NPPC ARID1A CIC ARID1B KMT2D TNRC6A SHARPIN	3.72e-05	121	152	7	int:EYA2
Interaction	PAX2 interactions	BCL9 CIC ARID1B KMT2D ZFHX4 MAPK8	4.46e-05	85	152	6	int:PAX2
Interaction	NR3C1 interactions	JCAD ZNF142 HYOU1 LRRC37A3 SF3A1 RAD54L2 BCL9 ARID1A POM121C CIC RYR1 TGFB1I1 ARID1B KMT2D AATF TIGD5 MAPK8 CUX1 RAI1 RAD9A	4.51e-05	974	152	20	int:NR3C1
Interaction	GATA1 interactions	TNS2 CHD4 BCL9 ARID1A ARID1B KMT2D CCAR1 RAI1	4.74e-05	171	152	8	int:GATA1
Interaction	GSC interactions	BCL9 ARID1B TNRC18 KMT2D ZFHX4 ZFHX3	5.09e-05	87	152	6	int:GSC
Interaction	NFIX interactions	ARID1A CIC ARID1B KMT2D ZFHX4 EHMT2 ZNF746 ZFHX3 CUX1	5.80e-05	227	152	9	int:NFIX
Interaction	TEAD1 interactions	ARID1A CIC ARID1B KMT2D ZFHX4 EHMT2 ZFHX3 CUX1	5.81e-05	176	152	8	int:TEAD1
Interaction	CEBPA interactions	SETX HYOU1 UNCX SF3A1 CHD4 RAD54L2 BCL9 ARID1A AHDC1 CIC SCAF4 PRAM1 ARID1B TNRC18 KMT2D PRRC2C SHARPIN CCAR1 MAPK8 PRRC2A MED12 CUX1 RAI1	5.96e-05	1245	152	23	int:CEBPA
Interaction	CNOT9 interactions	GIGYF1 PCGF6 ALMS1 PRRC2C TNRC6A STRN4 MEPCE TNKS1BP1 PRRC2A	6.63e-05	231	152	9	int:CNOT9
Interaction	SOX17 interactions	BCL9 ARID1A CIC ARID1B KMT2D EHMT2	8.34e-05	95	152	6	int:SOX17
Interaction	HDAC1 interactions	EPS15 SF3A1 CHD4 ARID1A CIC TAF6L PCGF6 TNRC18 KMT2D ALMS1 ZFHX4 EHMT2 ZNF592 TNRC6A ZFHX3 TNKS1BP1 MAPK8 MED12 CUX1 RAI1 RAD9A	9.02e-05	1108	152	21	int:HDAC1
Interaction	SOX15 interactions	BCL9 ARID1A CIC ARID1B KMT2D EHMT2 CUX1	9.83e-05	141	152	7	int:SOX15
Interaction	HNF1B interactions	BCL9 ARID1A CIC ARID1B KMT2D ZFHX4 ZFHX3 CUX1	9.93e-05	190	152	8	int:HNF1B
Interaction	LHX1 interactions	BCL9 ARID1A ARID1B KMT2D ZFHX4 EHMT2	1.31e-04	103	152	6	int:LHX1
Interaction	FASLG interactions	NCKIPSD TNS2 SH3PXD2B SRGAP3 MAPK8 MYO15A	1.45e-04	105	152	6	int:FASLG
Interaction	NAA40 interactions	EPS15 MAP1A CDK12 SF3A1 PYM1 CHD4 POM121C CIC SCAF4 EPS15L1 ALMS1 PRRC2C FHOD1 MEPCE PPP1R9B TNKS1BP1 PPP6R2 PRRC2A SON	1.46e-04	978	152	19	int:NAA40
Interaction	E2F5 interactions	ARID1A PCGF6 ARID1B KMT2D	1.52e-04	36	152	4	int:E2F5
Interaction	FBXO42 interactions	BDP1 MAP1A MYO9B ARID1A STK11 ALMS1 TNRC6A TNKS1BP1 PPP6R2	1.58e-04	259	152	9	int:FBXO42
Interaction	GCM1 interactions	BCL9 ARID1A CIC ARID1B KMT2D	1.62e-04	68	152	5	int:GCM1
Interaction	MEX3A interactions	MYO9B TBC1D2 CHD4 ARID1A AHDC1 SH3PXD2B TNRC18 PRRC2C TNKS1BP1 PRRC2A SON	1.64e-04	384	152	11	int:MEX3A
Interaction	H2AX interactions	HYOU1 TAF1C CHD4 ZC3H18 GPATCH8 ARID1A STK11 ARID1B TNRC18 EHMT2 ZNF592 MEPCE PPP1R9B MAPK8	1.64e-04	593	152	14	int:H2AX
Interaction	ATG16L1 interactions	MAP1A CDK12 INPPL1 PPP1R13B PYM1 CCDC168 GIGYF1 GPATCH8 TGFB1I1 EPS15L1 PRRC2C TNRC6A STRN4 MEPCE CCAR1 PPP1R18 PPP1R9B KATNIP PPP6R2 PRRC2A FHIP1A	1.73e-04	1161	152	21	int:ATG16L1
Interaction	ETV4 interactions	BCL9 ARID1A STK11 ARID1B KMT2D	1.74e-04	69	152	5	int:ETV4
Interaction	GAS7 interactions	SF3A1 NCKIPSD CREB3L2 MYBPC2	1.88e-04	38	152	4	int:GAS7
Interaction	SOX6 interactions	POMGNT1 CIC ZFHX4 PRRC2C ZFHX3 PRRC2A CUX1	1.92e-04	157	152	7	int:SOX6
Interaction	PAX8 interactions	BCL9 ARID1A CIC ARID1B KMT2D ZFHX4	1.97e-04	111	152	6	int:PAX8
Interaction	SOX5 interactions	CIC KMT2D ZFHX4 PRRC2C ZFHX3 PRRC2A CUX1	2.32e-04	162	152	7	int:SOX5
Interaction	MEN1 interactions	SF3A1 TAF1C CHD4 ZC3H18 ARID1A POM121C AHDC1 ARID1B KMT2D EHMT2 ZNF592 NFE2 MEPCE AATF TNKS1BP1 PRRC2A MED12 CUX1 SON	2.79e-04	1029	152	19	int:MEN1
Interaction	ERG interactions	RAD54L2 BCL9 ARID1A CIC ARID1B KMT2D ZFHX4 ZNF746	2.97e-04	223	152	8	int:ERG
Interaction	ELK3 interactions	CIC PCGF6 ZFHX4 EHMT2 ZNF746 MAPK8	3.00e-04	120	152	6	int:ELK3
Interaction	KPNA4 interactions	CHD4 POM121C CIC STK11 MEPCE CCAR1 PARD3 RAI1	3.15e-04	225	152	8	int:KPNA4
Interaction	KLF3 interactions	HYOU1 ARID1A CIC PCGF6 ARID1B KMT2D EHMT2 ZFHX3	3.44e-04	228	152	8	int:KLF3
Interaction	MAPRE3 interactions	MAP1A MYO9B APC2 PIK3R4 SH3PXD2B MAST4 PPP1R9B PRRC2A	3.65e-04	230	152	8	int:MAPRE3
Interaction	RCOR1 interactions	EPS15 CHD4 CIC KMT2D ALMS1 ZFHX4 EHMT2 ZNF592 ZFHX3 TNKS1BP1 MED12 CUX1	3.77e-04	494	152	12	int:RCOR1
Interaction	SUZ12 interactions	SETX SF3A1 PYM1 CHD4 ZC3H18 AHDC1 KMT2D ALMS1 EHMT2 ZNF592 TNRC6A PPP1R9B TNKS1BP1 SON	3.79e-04	644	152	14	int:SUZ12
Interaction	RNPS1 interactions	EPS15 CDK12 SF3A1 TAF1C PYM1 ZC3H18 GPATCH8 SCAF4 EPS15L1 AATF SON	3.90e-04	425	152	11	int:RNPS1
Interaction	SOX7 interactions	ARID1A ARID1B TNRC18 KMT2D ZFHX4	3.91e-04	82	152	5	int:SOX7
Interaction	CNOT2 interactions	GIGYF1 ALMS1 PRRC2C TNRC6A ZFHX3 TNKS1BP1 PRRC2A	4.11e-04	178	152	7	int:CNOT2
Interaction	SOX2 interactions	MAP1A MYO9B CDK12 PYM1 CHD4 BCL9 ARID1A AHDC1 CIC RYR1 OTUD7B TAF6L ARID1B TNRC18 C2CD3 KMT2D ZFHX4 EHMT2 TNRC6A MEPCE PPP1R9B ZFHX3 CUX1	4.18e-04	1422	152	23	int:SOX2
Interaction	NFE2 interactions	CHD4 KMT2D ZNF592 NFE2 MAPK8	4.37e-04	84	152	5	int:NFE2
Interaction	QPRT interactions	SF3A1 SCAF4 ARID1B PRRC2C CCAR1	4.37e-04	84	152	5	int:QPRT
Interaction	YWHAG interactions	JCAD CDK12 MBD1 NCKIPSD HECTD4 TNS2 GIGYF1 CIC PIK3R4 STK11 TBC1D10B C2CD3 MAST4 ALMS1 CASKIN2 PRRC2C MEPCE PPP1R9B PARD3 RGL2 SON	4.55e-04	1248	152	21	int:YWHAG
Interaction	ITGB2 interactions	SCARF2 SF3A1 CHD4 SH3PXD2B SHARPIN SON	5.00e-04	132	152	6	int:ITGB2
Interaction	MYB interactions	CIC PCGF6 KMT2D EHMT2 ZFHX3 CUX1	5.21e-04	133	152	6	int:MYB
Interaction	SMC5 interactions	SETX CDK12 SF3A1 CHD4 ZC3H18 ARID1A CIC SCAF4 PRAM1 EPS15L1 ARID1B PRRC2C CCAR1 AATF PRRC2A CUX1 RAI1 SON	5.50e-04	1000	152	18	int:SMC5
Interaction	CCAR1 interactions	SF3A1 CHD4 CIC MEPCE CCAR1 AATF TNKS1BP1	5.52e-04	187	152	7	int:CCAR1
Cytoband	Ensembl 112 genes in cytogenetic band chr15q25	WHAMM GOLGA6L4 GOLGA6L10 ADAMTS7 ZNF592	2.28e-04	160	156	5	chr15q25
Cytoband	15q25.2	WHAMM GOLGA6L4 GOLGA6L10	4.30e-04	43	156	3	15q25.2
Cytoband	2q24	NPPC LY75	6.18e-04	11	156	2	2q24
Cytoband	8q24.3	MROH1 SHARPIN TIGD5 PPP1R16A	6.19e-04	113	156	4	8q24.3
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	PPP1R13B PPP1R15A RYR1 PPP1R18 PPP1R9B PARD3 SPOCD1 PPP1R16A	6.31e-06	181	98	8	694
GeneFamily	Ataxins\|Trinucleotide repeat containing	TNRC18 KMT2D TNRC6A MED12	9.41e-06	25	98	4	775
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZFHX4 ZFHX2 ZFHX3	6.70e-05	15	98	3	529
GeneFamily	C2-set domain containing\|Immunoglobulin like domain containing\|Scavenger receptors	SCARF2 SSC5D LY75	4.11e-04	27	98	3	1253
GeneFamily	AT-rich interaction domain containing	ARID1A ARID1B	2.92e-03	15	98	2	418
GeneFamily	WD repeat domain containing\|Protein phosphatase 2 regulatory subunits	PPP2R5B STRN4	2.92e-03	15	98	2	696
GeneFamily	LIM domain containing	TGFB1I1 MICAL2 FBLIM1	4.03e-03	59	98	3	1218
Coexpression	THAKAR_PBMC_INACTIVATED_INFLUENZA_AGE_21_30YO_RESPONDERS_28DY_DN	LILRB3 ZNF142 MYO9B TAF1C MBD1 TBC1D2 RAPGEF1 RAD54L2 PPP1R15A TAF6L PRAM1 ZNF746 PPP1R18 KATNIP ZFHX3 TAGLN CUX1 RAI1	7.23e-06	905	155	18	M40865
Coexpression	THAKAR_PBMC_INACTIVATED_INFLUENZA_AGE_21_30YO_RESPONDERS_7DY_DN	LILRB3 TAF1C TBC1D2 HECTD4 WHAMM RAD54L2 PPP1R15A TAF6L PPP1R18 KATNIP ZFHX3 TAGLN CUX1 RAI1	2.57e-05	634	155	14	M40866
Coexpression	GSE31082_DN_VS_CD8_SP_THYMOCYTE_DN	EPS15 CHIT1 KMT2D ZNF592 ARHGEF3 LY75 SON RAD9A	2.64e-05	200	155	8	M5063
Coexpression	GSE1432_CTRL_VS_IFNG_6H_MICROGLIA_UP	FRMPD1 NCKIPSD CHD4 PIK3R4 STK11 C2CD3 MICAL2 CREB3L2	2.64e-05	200	155	8	M3404
Coexpression	GINESTIER_BREAST_CANCER_ZNF217_AMPLIFIED_DN	MYO9B TAF1C GIGYF1 RAD54L2 CIC STK11 KMT2D EHMT2 PPP6R2 PRRC2A	3.50e-05	338	155	10	M17094
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5\|TCGA-Ovary / Sample_Type by Project: Shred V9	HECTD4 CHD4 ARID1A ARID1B SRGAP3 MEPCE KATNIP SON	1.32e-07	166	156	8	32d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCell	pdx\|World / Sample and Cell Type and Tumor Cluster (all cells)	SLC22A23 HECTD4 GPATCH8 ARID1A ARID1B TNRC18 PPP6R2 CUX1	3.16e-07	186	156	8	de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCell	pdx-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	SLC22A23 HECTD4 GPATCH8 ARID1A ARID1B TNRC18 PPP6R2 CUX1	3.16e-07	186	156	8	0b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW08-Mesenchymal\|GW08 / Sample Type, Dataset, Time_group, and Cell type.	ZNF142 TEX2 NCKIPSD FHOD1 AATF ARHGAP20 CNGB1 CREB3L2	5.47e-07	200	156	8	e5b7d9622b96bb20c81ac76b4e60e8b44fa9cca1
ToppCell	Adult-Immune-alveolar_macrophage_(MARCO_positive)-D122\|Adult / Lineage, Cell type, age group and donor	MYO9B TEX2 RAPGEF1 PRAM1 SH3PXD2B TAGLN SPOCD1	5.44e-06	193	156	7	cc1b6d3bf56e4a88f6fe23dd036a83cf5538c958
ToppCell	356C-Endothelial_cells-Endothelial-F_(Lymphatics)-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	NPPC ZFHX4 SRGAP3 MICAL2 PALM GPSM2 ZFHX3	6.02e-06	196	156	7	b04ca69b0ed44e09c989b575f747e1e819cd8008
ToppCell	356C-Endothelial_cells-Endothelial-F_(Lymphatics)\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	NPPC ZFHX4 SRGAP3 MICAL2 PALM GPSM2 ZFHX3	6.02e-06	196	156	7	a31e227de2dc077b81881295b012d22fedbd65ed
ToppCell	Tracheal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SLC22A23 PPP1R13B BCAS1 SRGAP3 CRACDL ARHGEF3 FHIP1A	6.87e-06	200	156	7	d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCell	TCGA-Thymus-Primary_Tumor-Thymoma-Type_AB\|TCGA-Thymus / Sample_Type by Project: Shred V9	JCAD SCARF2 TNS2 RYR1 TGFB1I1 PALM	3.56e-05	175	156	6	50f9b994bdd389158f92f891944ea81b2fb15eef
ToppCell	5'-Adult-Distal_Rectal-Epithelial-goblet-Goblet_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZNF142 ZC3H18 RAD54L2 MROH1 PPP1R9B KATNIP	3.80e-05	177	156	6	e1e45956887371b1c18f1eb479dd930031497520
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c02-AQP3\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	HYOU1 PYM1 BCL9 GOLGA6L4 PRRC2A XKR5	4.17e-05	180	156	6	81d60f0fa9e3b5bfcec85139a0a49e9130145f0e
ToppCell	(2)_5-FU-(4)_COL2.3+_osteoblasts\|(2)_5-FU / Stress and Cell class	NIBAN1 SLC1A4 SH3PXD2B MICAL2 GPSM2 ZFHX3	4.30e-05	181	156	6	56ae86072858c156681507aecd1bc6cb0a3372d2
ToppCell	COPD-Epithelial-Basal\|World / Disease state, Lineage and Cell class	NPPC SLC22A23 MAST4 PTPRQ PARD3 FHIP1A	4.30e-05	181	156	6	6d8a886b4afe729f8a05b9c0f4ea9375de735da4
ToppCell	Control-Epithelial-Basal\|World / Disease state, Lineage and Cell class	NPPC SLC22A23 SRGAP3 PTPRQ PARD3 FHIP1A	4.43e-05	182	156	6	759390dde9b18757f7675d13d44c89d0e32f8d93
ToppCell	Control-Epithelial-Basal\|Control / Disease state, Lineage and Cell class	NPPC SLC22A23 SRGAP3 PTPRQ PARD3 FHIP1A	4.43e-05	182	156	6	caddd0a52f0234ea6a916186ffaf2454cdcd80ee
ToppCell	(2)_5-FU-(4)_COL2.3+_osteoblasts\|World / Stress and Cell class	NIBAN1 SLC1A4 SH3PXD2B MICAL2 GPSM2 ZFHX3	4.71e-05	184	156	6	684d05340a3dfb8aa08b881516a37f9627a10448
ToppCell	390C-Lymphocytic-CD4_T-cell-Treg_cell_3\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	NIBAN1 RYR1 ZBTB45 MAST4 MROH1 FHOD1	5.00e-05	186	156	6	74eb69a52090f9e2426a47e03a1c478ee0cfec18
ToppCell	Substantia_nigra\|World / BrainAtlas - Mouse McCarroll V32	UNCX BCAS1 ZFHX4 INSYN2B ZFHX3	5.30e-05	115	156	5	18174b8d57d444fab1e9d2b13d22939c83c958e0
ToppCell	COVID-19-Epithelial_cells\|COVID-19 / group, cell type (main and fine annotations)	SLC22A23 PPP1R13B MAST4 MICAL2 PARD3 FHIP1A	5.31e-05	188	156	6	c9cdee6f8d42ee69f5fb335f25084603c511bd29
ToppCell	P07-Mesenchymal-myocytic_cell-vascular_associated_smooth_muscle_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	NIBAN1 XIRP1 MAP1A ZFHX3 TAGLN FBLIM1	5.31e-05	188	156	6	6ec22b79b19d57ea187f312907819dc2d01f3efe
ToppCell	droplet-Kidney-nan-21m-Epithelial-kidney_mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XIRP1 MAP1A GDNF TGFB1I1 ZFHX3 TAGLN	5.63e-05	190	156	6	1803b1e7c36285f9eaabc3c6e9a9752c5908db3d
ToppCell	3'-Adult-LargeIntestine-Mesenchymal-myocytic-myofibroblast\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SCARF2 GDNF TGFB1I1 TAGLN SPOCD1 SEZ6L	5.63e-05	190	156	6	591310e615700321a010a4b90405cbbbbdb3aade
ToppCell	COVID-19-lung-Macrophage_PPARGhi_CD5Lhi\|lung / Disease (COVID-19 only), tissue and cell type	MYO9B TBC1D2 RAPGEF1 PRAM1 SH3PXD2B SPOCD1	5.80e-05	191	156	6	dab953682b8c9ed680a799161f837f792a7e4f33
ToppCell	Adult-Epithelial\|Adult / Lineage, Cell type, age group and donor	SLC22A23 PPP1R13B MAST4 MICAL2 PARD3 FHIP1A	5.97e-05	192	156	6	efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCell	droplet-Kidney-nan-3m-Epithelial-kidney_mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XIRP1 MAP1A GDNF TGFB1I1 ZFHX3 TAGLN	5.97e-05	192	156	6	3617d2bc7e33d981f3ec349e9962d8d4bd822fbd
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	ARID1B MAST4 TNRC6A MAPK8 PARD3 CUX1	5.97e-05	192	156	6	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NIBAN1 XIRP1 ZFHX3 TAGLN FBLIM1 SEZ6L	6.14e-05	193	156	6	469a7f1c2ff7137cc5a064464456911f67f92e70
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NIBAN1 XIRP1 ZFHX3 TAGLN FBLIM1 SEZ6L	6.14e-05	193	156	6	323d1f3f4fbeb93ba857fc135d8aa0b897f98ac5
ToppCell	wk_08-11-Hematologic-Meg-ery-Definitive_erythroblast\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	SLC22A23 MEIKIN HECTD4 STK11 NFE2 MICAL2	6.14e-05	193	156	6	be75abfdf5301cf33df8ee9ed92504d44fdf19a6
ToppCell	TCGA-Thryoid-Primary_Tumor\|TCGA-Thryoid / Sample_Type by Project: Shred V9	TBC1D2 GRB7 TGFB1I1 CRACDL FHOD1 PPP1R9B	6.50e-05	195	156	6	7cdee2ae90edf15e4cbcf70797b8caf1f037b0ef
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NIBAN1 ZFHX4 PRRC2C ARHGAP20 CREB3L2 MYBPC2	6.50e-05	195	156	6	5c86fddd6d0530beecf45ea5ba6b823123847696
ToppCell	TCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma\|TCGA-Thryoid / Sample_Type by Project: Shred V9	TBC1D2 GRB7 TGFB1I1 CRACDL FHOD1 PPP1R9B	6.50e-05	195	156	6	b61b8c931bd0ca3678486653ae1d7e9915c696c7
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Mesenchymal-Pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XIRP1 TGFB1I1 MICAL2 ZFHX3 TAGLN FBLIM1	6.69e-05	196	156	6	184104cbea0461dd2757668ab9755948ac7b585a
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Mesenchymal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XIRP1 TGFB1I1 MICAL2 ZFHX3 TAGLN FBLIM1	6.69e-05	196	156	6	bebb20dc210576101c317011e3afb59798f5d255
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Mesenchymal-brain_pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XIRP1 TGFB1I1 MICAL2 ZFHX3 TAGLN FBLIM1	6.69e-05	196	156	6	8114e98923096c54b6834f21550c3061bab6773d
ToppCell	Parenchymal-10x3prime_v2-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	ADAT3 AIF1L OTUD7B ZFHX3 TAGLN HES5	6.88e-05	197	156	6	470e23dee4ca35e1fd021b7cdd58fcbc90639837
ToppCell	Bronchial-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SLC22A23 PPP1R13B MAST4 MICAL2 PARD3 FHIP1A	7.27e-05	199	156	6	5f7da3eab58ace6cddb3179a415cd839d5767958
ToppCell	Control_saline-Endothelial-Endothelial-Alv_Gen_Intermediate\|Control_saline / Treatment groups by lineage, cell group, cell type	JCAD SETX CASKIN2 PPP1R9B ARHGEF3 RGL2	7.48e-05	200	156	6	041a34080120c9f613373c20dcc366292f558040
ToppCell	Control_saline-Endothelial-Endothelial\|Control_saline / Treatment groups by lineage, cell group, cell type	JCAD SETX CASKIN2 PPP1R9B ARHGEF3 RGL2	7.48e-05	200	156	6	e77eba6172cabf85b8028638ed35299f2f079cd8
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Alv_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	JCAD SETX NCKIPSD CASKIN2 PPP1R9B ARHGEF3	7.48e-05	200	156	6	7034f57e282982c19c13ee8ab78eabaffa069e30
ToppCell	Control_saline-Endothelial\|Control_saline / Treatment groups by lineage, cell group, cell type	JCAD SETX CASKIN2 PPP1R9B ARHGEF3 RGL2	7.48e-05	200	156	6	3372c488a39fe812fa94e4f0564594186fea3db5
Drug	Ungerine nitrate; Down 200; 10.2uM; MCF7; HT_HG-U133A	INPPL1 MBD1 RTL10 AHDC1 ZNF592 CASKIN2 STRN4 PPP6R2 PRRC2A MED12	1.01e-06	199	153	10	7173_DN
Drug	Iohexol [66108-95-0]; Up 200; 4.8uM; MCF7; HT_HG-U133A	RAD54L2 ARID1A CIC PPP2R5B SLC9A5 ALMS1 FHOD1 STRN4 PPP6R2 PRRC2A	1.05e-06	200	153	10	3322_UP
Drug	Pipenzolate bromide [125-51-9]; Down 200; 9.2uM; MCF7; HT_HG-U133A	MYO9B MBD1 BCAS1 SCAF4 TGFB1I1 STK11 ZNF592 ZFHX3 PARD3	7.11e-06	195	153	9	6821_DN
Drug	Chloroquine diphosphate [50-63-5]; Up 200; 7.8uM; MCF7; HT_HG-U133A	TBC1D2 RAD54L2 PPP1R15A ARID1A SLC1A4 PPP2R5B SLC9A5 CASKIN2 PARD3	7.72e-06	197	153	9	2869_UP
Drug	LY 294002; Up 200; 0.1uM; MCF7; HT_HG-U133A	MYO9B TNS2 SLC1A4 CIC ALMS1 ADAMTS7 FHOD1 PALM MED12	8.04e-06	198	153	9	6976_UP
Drug	Delsoline [509-18-2]; Down 200; 8.6uM; PC3; HT_HG-U133A	JCAD MYO9B MBD1 PPP1R15A PPP2R5B MAST4 ALMS1 AATF PARD3	8.04e-06	198	153	9	5858_DN
Disease	Malignant neoplasm of breast	XIRP1 ADAT3 SCARF2 APC2 FRMPD1 LRRC37A2 GRB7 ARID1A CIC PIK3R4 ARID1B KMT2D LRRC37A SRGAP3 SPOCD1 PRRC2A MED12 CUX1	9.41e-06	1074	150	18	C0006142
Disease	bitter alcoholic beverage consumption measurement	UNCX PPP1R13B CIC TNRC6A PALM ZFHX3	6.30e-05	133	150	6	EFO_0010092
Disease	schizophrenia, anorexia nervosa	PPP1R13B PCGF6 ALMS1 ZNF592	1.05e-04	48	150	4	MONDO_0005090, MONDO_0005351
Disease	charged multivesicular body protein 3 measurement	CHMP3 ARHGEF3	1.53e-04	4	150	2	EFO_0801469
Disease	hepatocellular carcinoma (is_marker_for)	CDK12 GRB7 CHD4 ARID1A PPP1R9B ZFHX3 MAPK8 CUX1	1.61e-04	301	150	8	DOID:684 (is_marker_for)
Disease	viral infectious disease (implicated_via_orthology)	EHMT2 PTPRQ	2.54e-04	5	150	2	DOID:934 (implicated_via_orthology)
Disease	Malignant Cystosarcoma Phyllodes	KMT2D MED12	2.54e-04	5	150	2	C0600066
Disease	Phyllodes Tumor	KMT2D MED12	2.54e-04	5	150	2	C0010701
Disease	MENTAL RETARDATION, AUTOSOMAL DOMINANT 12	ARID1A ARID1B	2.54e-04	5	150	2	C3281201
Disease	Hirschsprung Disease	GDNF ARID1B MED12	5.21e-04	31	150	3	C0019569
Disease	sexual dimorphism measurement	NPPC ZNF142 MYO9B RAD54L2 ARID1A GDNF GOLGA6L4 PRAM1 SSC5D ZNF592 TNRC6A ZFHX3 TAGLN SPOCD1 NPAS1	5.35e-04	1106	150	15	EFO_0021796
Disease	Growth Disorders	NPPC SH3PXD2B RAI1	8.13e-04	36	150	3	C0018273
Disease	chronic obstructive pulmonary disease	CCDC192 JCAD SCARF2 MBD1 LRRC37A2 BCL9 OTUD7B EHMT2 SRGAP3 PPP1R18 CC2D2A	8.17e-04	688	150	11	EFO_0000341
Disease	BMI-adjusted waist circumference, forced expiratory volume	NPPC OTUD7B	9.03e-04	9	150	2	EFO_0004314, EFO_0007789
Disease	attention deficit hyperactivity disorder, autism spectrum disorder, intelligence	SLC22A23 NCKIPSD ARID1B KMT2D TNRC6A FHIP1A NPAS1 PPP1R16A	1.02e-03	398	150	8	EFO_0003756, EFO_0003888, EFO_0004337
Disease	mean arterial pressure	NIBAN1 MYO9B HECTD4 TNS2 POM121C GDNF TNRC6A ZFHX3 ARHGEF3	1.07e-03	499	150	9	EFO_0006340
Disease	Kunitz-type protease inhibitor 2 measurement	RYR1 ARHGEF3	1.12e-03	10	150	2	EFO_0008200
Disease	neuroblastoma (is_implicated_in)	ARID1A ARID1B	1.12e-03	10	150	2	DOID:769 (is_implicated_in)
Disease	retinitis pigmentosa (is_implicated_in)	POMGNT1 CC2D2A CNGB1	1.19e-03	41	150	3	DOID:10584 (is_implicated_in)
Disease	Prostatic Neoplasms	CDK12 MBD1 TBC1D2 GRB7 BCAS1 ARID1A KMT2D ZFHX3 PARD3 MED12	1.26e-03	616	150	10	C0033578
Disease	Malignant neoplasm of prostate	CDK12 MBD1 TBC1D2 GRB7 BCAS1 ARID1A KMT2D ZFHX3 PARD3 MED12	1.26e-03	616	150	10	C0376358
Disease	spleen volume	MYO9B HECTD4 GDNF	1.37e-03	43	150	3	EFO_0600047
Disease	mitochondrial DNA measurement	NCKIPSD STK11 NFE2 ARHGEF3 LY75 CUX1 RAI1	1.49e-03	328	150	7	EFO_0006312
Disease	methionine sulfone measurement	CDK12 ALMS1	1.64e-03	12	150	2	EFO_0800072
Disease	Congenital muscular dystrophy	POMGNT1 RYR1	1.64e-03	12	150	2	cv:C0699743
Disease	creatinine measurement	UNCX CDK12 BCAS1 ARID1A RYR1 TBC1D10B ALMS1 ADAMTS7 ZNF592 PRRC2C ZFHX3 PARD3 CUX1	1.76e-03	995	150	13	EFO_0004518
Disease	Coffin-Siris syndrome	ARID1A ARID1B	1.93e-03	13	150	2	C0265338
Disease	mean platelet volume	JCAD NIBAN1 MYO9B CDK12 TEX2 SLC22A23 BCAS1 MAST4 NFE2 TNRC6A ARHGEF3 LY75 CUX1	2.18e-03	1020	150	13	EFO_0004584
Disease	Nonsyndromic Hearing Loss and Deafness, Autosomal Recessive	PTPRQ GPSM2 MYO15A	2.24e-03	51	150	3	cv:CN043650
Disease	N-acetylmethionine measurement	ALMS1 MICAL2	2.58e-03	15	150	2	EFO_0021427
Disease	heart failure	HECTD4 POM121C ZNF592 CHMP3 ZFHX3	2.61e-03	185	150	5	EFO_0003144
Disease	pancreatitis	JCAD HECTD4	2.94e-03	16	150	2	EFO_0000278
Disease	T-Cell Lymphoma	ARID1A KMT2D	2.94e-03	16	150	2	C0079772
Disease	thyroid volume	NIBAN1 AATF	2.94e-03	16	150	2	EFO_0004865
Disease	creatinine measurement, glomerular filtration rate	UNCX CDK12 BCAS1 ALMS1	3.05e-03	117	150	4	EFO_0004518, EFO_0005208
Disease	immature platelet measurement	JCAD MYO9B PPP1R9B ARHGEF3	3.24e-03	119	150	4	EFO_0803541
Disease	1-Methylhistidine measurement	CDK12 ALMS1	3.32e-03	17	150	2	EFO_0021543
Disease	platelet crit	JCAD RETREG2 MAP1A MYO9B ZC3H18 GPATCH8 ARID1A MAST4 ARHGEF3 LY75 FHIP1A CUX1	3.51e-03	952	150	12	EFO_0007985
Disease	blood metabolite measurement	ALMS1 PPP1R16A	4.15e-03	19	150	2	EFO_0005664
Disease	Coronary Arteriosclerosis	JCAD HECTD4 ADAMTS7	4.47e-03	65	150	3	C0010054
Disease	Coronary Artery Disease	JCAD HECTD4 ADAMTS7	4.47e-03	65	150	3	C1956346
Disease	seborrheic dermatitis	TNRC18 MAST4	4.59e-03	20	150	2	EFO_1000764
Disease	breast carcinoma (is_marker_for)	STK11 KMT2D ZFHX3	4.66e-03	66	150	3	DOID:3459 (is_marker_for)
Disease	obesity (implicated_via_orthology)	ALMS1 ZFHX4 ZFHX2 ZFHX3 MED12	4.94e-03	215	150	5	DOID:9970 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
SPGLSPVPPPDKVDG	PPP2R5B	16	Q15173
NESSPKPVGPPPERD	AIF1L	131	Q9BQI0
PKCLEAGSPEPEPAP	ADAT3	11	Q96EY9
GAVPVLPASPPPKDS	EPS15L1	221	Q9UBC2
PPDPATDSASKPAEP	BDP1	36	A6H8Y1
PSKVTDALPEPEPPG	CHMP3	181	Q9Y3E7
PGGDLSPPDSPEPKA	CDK12	676	Q9NYV4
LPPASGPAKDAEEPS	ARHGEF3	21	Q9NR81
PSLDGPDPEKDPSVL	CCAR1	506	Q8IX12
DSKPPEPSDPPASDS	CUX1	1086	P39880
KESTPGPKEPPVLPS	RTL10	261	Q7L3V2
VPPVPGPDAQKTETP	ALMS1	1691	Q8TCU4
EPPPATTSPEGQPKV	EHMT2	166	Q96KQ7
PPGPPLLSKPGDEDD	ARID1B	256	Q8NFD5
PGPGPVSVPELKPES	AHDC1	441	Q5TGY3
PKAPDPEGLARPVSP	RAD54L2	1156	Q9Y4B4
GAPPKVPRTPPAEEL	NPPC	26	P23582
PVAEAPSPGEEQVPP	PPP1R13B	836	Q96KQ4
PPAKDIIDFPSVPPG	ADAMTS7	451	Q9UKP4
GEPATKLPPPETPDA	RAI1	1286	Q7Z5J4
EPKEPAPPNGSAAEP	PALM	336	O75781
PQPPKSPGPHSEEED	RAD9A	331	Q99638
EAEPSTVPGTPPPKK	RAD9A	346	Q99638
PTEPEPPTEGKQAAP	NPAS1	436	Q99742
TTDQEGPPPDGPPEK	ARID1A	1891	O14497
GPPPDGPPEKRITAT	ARID1A	1896	O14497
PSGTPELEVPKPGQP	CHIT1	391	Q13231
KPEPDAREEQPTGPP	OTUD7B	666	Q6GQQ9
PPELRVKSDEPPGPS	LRRC37A3	196	O60309
PPPATTKGPTVPDED	GPSM2	616	P81274
PSAPGQESPIPDPKL	MAP1A	1811	P78559
REKAALGDLTPPPPP	GIGYF1	586	O75420
PPELRVKSDEPPGPS	LRRC37A2	196	A6NM11
PPELRVKSDEPPGPS	LRRC37A	196	A6NMS7
FLVPAPPPPLKDESG	MEPCE	11	Q7L2J0
RPPEPKPIPGLDAST	MYO15A	2436	Q9UKN7
PASPLQDAEGPPAKP	KATNIP	366	O60303
DPVPEPEPSPLESKF	JCAD	1186	Q9P266
DPGLPSVKQEPPDPE	MBD1	531	Q9UIS9
PLLDPPPEESKSGEA	GPATCH8	1201	Q9UKJ3
PSPEGPPETPKGAAL	MMP21	71	Q8N119
DPSEAEAPPPKIPDK	MAPK8	326	P45983
PGPKEPVLDPTDCGP	FAM214B	291	Q7L5A3
GEKKAPEGSPPPLFP	GSX1	16	Q9H4S2
GPELTAPAPEPPAEE	COG8	571	Q96MW5
GPEEASPKPDDPCPE	LY75	631	O60449
PPKTDKPGAAPPSTE	MED12	1766	Q93074
PTPDLGSPAKAEAPP	MEIKIN	21	A0A087WXM9
EPLAPEPPAGPSKVE	GOLGA6L3	146	A6NEY3
EPLAPEPPAGPSKVE	GOLGA6L4	146	A6NEF3
EPLAPEPPAGPSKVE	GOLGA6L10	146	A6NI86
EPLAPEPPAGPSKVE	GOLGA6L19	146	H0YKK7
PLPAGKRPPEAPAED	GDNF	21	P39905
KATEPPPSQEGEPPA	LILRB3	606	O75022
KPELPPGLSPEATAP	PYM1	56	Q9BRP8
TSGPDPHPPPIADDE	HECTD4	2221	Q9Y4D8
LPPEQEPEKPGPGSK	MROH1	441	Q8NDA8
KGPPGPAPEPEREAE	CRACDL	451	Q6NV74
PPPLDESPGPKEGAT	CASKIN2	886	Q8WXE0
GTPRPPDTPLPEEVK	GRB7	26	Q14451
ISTKTLPGPPDGPPE	PTPRQ	1571	Q9UMZ3
APPKSEKEGLTPPGP	POM121C	711	A8CG34
FTAPPKSEKEGPTPP	POM121B	316	A6NF01
GPPAAEAATKKPLPP	APC2	746	O95996
DLEVSGPPAPIDPPK	FHIP1A	601	Q05DH4
PPPPEPKGDATPEGE	HYOU1	636	Q9Y4L1
KPKPQVPPGFPSAEE	CC2D2A	176	Q9P2K1
YPEEDLVKPSPPEPT	CC2D2A	611	Q9P2K1
APDKGTDSPSPPPLE	C2CD3	2011	Q4AC94
DKLTPPGPPSGPRDV	FRMPD1	776	Q5SYB0
ADPKAPPPPPVSSGE	BCL9	326	O00512
VTPGAEEPSIPEPPK	BFSP1	576	Q12934
PLPPEASPSREKPGL	MAST4	1956	O15021
PPVKPGIPASPKADT	ITIH6	761	Q6UXX5
LPPPPAEPVEKGAST	FBLIM1	166	Q8WUP2
DEPPALPPKIGTPTR	EPS15	766	P42566
PDDLKSPPFPEGPDT	CCDC168	6376	Q8NDH2
ESVEAGKDIPAPSPP	FHOD1	561	Q9Y613
PPQEVKDPPGCLPEA	CCDC192	261	P0DO97
ITPPEPEPTGAPQKG	BCAS1	481	O75363
DPNTPSPKPLEGRPE	CHD4	526	Q14839
PNTPAPVPPAEDGIK	CHD4	1551	Q14839
PEPPESAEKLLESPG	PPP1R18	356	Q6NYC8
NEGSPPPPVKVSSEP	SCAF4	151	O95104
TPAEPPTPEGSPILK	RYR1	4461	P21817
APPSPPPKKEEAGGE	RYR1	4526	P21817
SSPGPPPKQADLPDA	PRRT3	301	Q5FWE3
KDSPGPQPTDPPASE	PRRT3	316	Q5FWE3
KTEPVTDEPPPGLVP	CREB3L2	126	Q70SY1
GAPPAPGKKEAPPVE	PPP6R2	691	O75170
LEGSPPDEPTSPKRP	MICAL2	1106	O94851
KRPETPTHDPDPETP	PPP1R15A	536	O75807
PKGLKPSSGPPPEEE	OTOL1	41	A6NHN0
KTEGAAALPPPPPVS	PCGF6	16	Q9BYE7
KSPGSPPGPELPIET	PARD3	691	Q8TEW0
LPAGPPKPQEDPESD	NFE2	131	Q16621
EEKIASPKGPLEPPP	ARHGAP20	1061	Q9P2F6
PRPPGDKKEPAAAPD	TAF6L	466	Q9Y6J9
DLPKPLALPGDPPAD	RGL2	221	O15211
PETPTGDSDPQPAPK	SPANXA1	26	Q9NS26
TEKPGPPGDPDPIVA	SEZ6L	161	Q9BYH1
SDAKVPPASPPPDLG	TMEM191B	226	P0C7N4
DTPPLPSPPDKGDNA	SLC22A23	181	A1A5C7
PAAEPPPAPESGLED	TAF1C	701	Q15572
PIFLEPPPKEEGAPG	POMGNT1	641	Q8WZA1
GPLVRSKPSEPPPGD	MRAP	151	Q8TCY5
LPEFGAVSLKPPPPE	PRAM1	61	Q96QH2
ELGLEPETPPKPPDA	RETREG2	506	Q8NC44
PGVAAPPEVAPAPKS	PRRC2C	106	Q9Y520
PQLPSKEGPEPPEEV	PRRC2A	591	P48634
AKLQRPPPEGPESPE	PPP1R16A	466	Q96I34
PLTPRLKPEGAPEPE	INPPL1	956	O15357
APEPEGVAAPPPKNS	INPPL1	966	O15357
KPPVRGEPPAASPEA	SETX	2601	Q7Z333
SPPEASTLKGPPPEA	SHARPIN	146	Q9H0F6
TQKPESPGEPPPGLE	SLC9A5	21	Q14940
LGPEPEPKPEAAVSP	WHAMM	61	Q8TF30
AEAPVPIPPSPDTKD	STK11	316	Q15831
PDGSKPVKVPENPPS	TAGLN	71	Q01995
EGSPESPKDPAPSPS	SSC5D	746	A1L4H1
DEEEGQKVPPPPETP	SF3A1	361	Q15459
HLGKPDPDATAPPEP	NPAP1	251	Q9NZP6
KEPKAPGAAPPPALS	HES5	131	Q5TA89
PPSKASAPEPPAEEE	NCKIPSD	261	Q9NZQ3
PACPKAPEEGSEPSP	RAX	71	Q9Y2V3
GKPEPAAQPVPESLP	AATF	421	Q9NY61
KGPPPTTEEEASGPP	CIC	121	Q96RK0
EPKEAPAPEPQPGSQ	CNGB1	226	Q14028
APEPAPDTKPAEAEP	CNGB1	606	Q14028
PPPQEGPEDKPTRFS	C11orf42	261	Q8N5U0
KRNGSLPDCPPPEDP	PIK3R4	751	Q99570
PASPPPTPGITRKEE	TNRC18	1036	O15417
GTSTPLIPSPKPEPE	ZFHX4	2341	Q86UP3
LPAPPTPAKAEGPDA	ZBTB45	181	Q96K62
AEPPKPPDGSLDSPV	ZFHX2	1531	Q9C0A1
PVPGPPTEPLGDKVS	ZFHX2	2296	Q9C0A1
KGESLSLPGPSPPPD	NIBAN1	636	Q9BZQ8
EPLKNPPGPVSSEPA	SRGAP3	996	O43295
TDEEVAPPKPPLPGI	RAPGEF1	261	Q13905
SDLGLEDSGPPPVPK	SLC1A4	151	P43007
ESVPSKLGEPPPLGE	SOGA3	151	Q5TF21
GPKPAELPPTPGTER	TMEM247	86	A6NEH6
PAPSPKTEPPQGEDQ	SH3PXD2B	646	A1X283
KEEPPGRPLTSSPDP	SPOCD1	186	Q6ZMY3
TPGPEKAATDLPAPE	SCARF2	826	Q96GP6
PDPDDPSKSPVGSPL	ZNF592	396	Q92610
EAGKEEPPPLTPPAR	TNKS1BP1	121	Q9C0C2
ASPEAPKPQLPSGPE	TBC1D10B	96	Q4KMP7
RDVDGLPPKVTGPPP	STRN4	361	Q9NRL3
SGAPKERPAEPLTPP	TGFB1I1	21	O43294
PSEKALLSEPPEPGG	TEX28	146	O15482
GPKIPDVPVDPSPGS	ZNF746	161	Q6NUN9
ETPAPKLPPGEREPS	ZNF142	91	P52746
KPPTPEQVPPEAGLG	XKR5	376	Q6UX68
SPAPGPPVKEEPALP	TIGD5	196	Q53EQ6
PPVKEEPALPSGAGP	TIGD5	201	Q53EQ6
PAEGSEDPKKPPRPQ	TEX2	661	Q8IWB9
EKDFQPSPDLIPPGP	XIRP1	326	Q702N8
KEVPPPPKETLPDSG	SON	1706	P18583
LGGPIPAPAKEEEPT	TNRC6A	971	Q8NDV7
PSKDPLEETPEAPVP	TNS2	1246	Q63HR2
DEGPPPAKLPCLSPE	nan	271	A6NL46
GREPEDSPKPAPKPS	TBC1D2	261	Q9BYX2
KTTAPVPEPTKPGDP	ZC3H18	651	Q86VM9
GLEPAPKDAPPAPAV	UNCX	401	A6NJT0
TPVPPGAPSPDKDPA	ZFHX3	3401	Q15911
AEPVEEASPPPKSPA	INSYN2B	496	A6NMK8
KPPEEPGQCPAPEEL	KMT2D	866	O14686
SPPAPGSAPETPEDK	MYO9B	1261	Q13459
APKEAPPKEAPAEAP	MYBPC2	21	Q14324
PPPPAPSGDAPAEKE	PPP1R9B	256	Q96SB3