Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	IgG receptor activity	FCGR2C FCGR2A FCGR2B	1.69e-05	7	159	3	GO:0019770
GeneOntologyMolecularFunction	IgG binding	FCGR2C FCGR2A FCGR2B	7.80e-05	11	159	3	GO:0019864
GeneOntologyMolecularFunction	hydrolase activity, acting on ester bonds	CDKN3 ABHD15 PDE4C DUSP19 INPP5F PPEF2 LARS2 FAN1 PIKFYVE CILP2 MYG1 STS MTMR14 CPT1C PITPNM3 SSH2 DAGLA SMG6	7.91e-05	807	159	18	GO:0016788
GeneOntologyMolecularFunction	immunoglobulin receptor activity	FCGR2C FCGR2A FCGR2B	1.69e-04	14	159	3	GO:0019763
GeneOntologyMolecularFunction	calcium ion binding	TPO ASAH2 SHH CDH23 DUOX2 PPEF2 DLL1 ZZEF1 STIM1 NRXN1 PITPNM3 LRP2 MACF1 ASAH2B CDH16 DOC2B	3.26e-04	749	159	16	GO:0005509
GeneOntologyMolecularFunction	low-affinity IgG receptor activity	FCGR2A FCGR2B	3.74e-04	4	159	2	GO:0019772
GeneOntologyBiologicalProcess	immune complex clearance	CCR2 FCGR2A FCGR2B	3.51e-05	9	157	3	GO:0002434
GeneOntologyBiologicalProcess	regulation of vesicle-mediated transport	DOC2A ANKRD13D ANKFY1 STXBP5 INPP5F EIPR1 DLL1 CCR2 FCGR2C RAB3GAP1 NRXN1 FCGR2A FCGR2B PIK3CB LRP2 DOC2B	5.15e-05	667	157	16	GO:0060627
GeneOntologyBiologicalProcess	vesicle-mediated transport to the plasma membrane	STXBP5 INPP5F EIPR1 EPG5 FCGR2A FCGR2B SNX7 MACF1	5.29e-05	172	157	8	GO:0098876
GeneOntologyBiologicalProcess	negative regulation of type I hypersensitivity	FCGR2A FCGR2B	5.76e-05	2	157	2	GO:0001811
GeneOntologyBiologicalProcess	regulation of neutrophil apoptotic process	FCGR2A FCGR2B PIK3CB	6.83e-05	11	157	3	GO:0033029
GeneOntologyBiologicalProcess	phosphatidylinositol biosynthetic process	PIGS INPP5F PIKFYVE MTMR14 PIK3CB PI4KA PITPNM3	6.89e-05	132	157	7	GO:0006661
GeneOntologyBiologicalProcess	regulation of vascular endothelial growth factor signaling pathway	ADAMTS3 DLL1 ADGRA2 PIK3CB	7.59e-05	30	157	4	GO:1900746
GeneOntologyBiologicalProcess	endocytic recycling	INPP5F EIPR1 EPG5 FCGR2A FCGR2B SNX7	8.79e-05	95	157	6	GO:0032456
GeneOntologyBiologicalProcess	regulation of cellular response to vascular endothelial growth factor stimulus	ADAMTS3 DLL1 ADGRA2 PIK3CB	9.84e-05	32	157	4	GO:1902547
GeneOntologyBiologicalProcess	antibody-dependent cellular cytotoxicity	FCGR2C FCGR2A FCGR2B	1.17e-04	13	157	3	GO:0001788
GeneOntologyBiologicalProcess	neutrophil homeostasis	CCR2 FCGR2A FCGR2B PIK3CB	1.41e-04	35	157	4	GO:0001780
GeneOntologyBiologicalProcess	neutrophil apoptotic process	FCGR2A FCGR2B PIK3CB	1.48e-04	14	157	3	GO:0001781
GeneOntologyBiologicalProcess	endosomal transport	ANKFY1 HEATR5A INPP5F EIPR1 EPG5 PIKFYVE FCGR2A FCGR2B SNX7 LRP2	1.76e-04	320	157	10	GO:0016197
GeneOntologyBiologicalProcess	type IIa hypersensitivity	FCGR2C FCGR2A FCGR2B	1.84e-04	15	157	3	GO:0001794
GeneOntologyBiologicalProcess	type II hypersensitivity	FCGR2C FCGR2A FCGR2B	1.84e-04	15	157	3	GO:0002445
GeneOntologyBiologicalProcess	cellular catabolic process	TPO SRD5A3 RETREG2 ASAH2 TCIRG1 DUOX2 SPG11 APOB ATG2A INPP5F LCT EPG5 PIKFYVE RAB3GAP1 ACAD11 MTMR14 PIK3CB SNX7 ACSF3 TNFRSF1B DAGLA ASAH2B	2.11e-04	1253	157	22	GO:0044248
Domain	ARM-type_fold	MROH2A APOB HEATR5A RALGAPA2 NCAPG2 FOCAD DNAAF5 PIK3CB PI4KA NCAPD2 IPO13 NUP188 UNC79	5.59e-06	339	156	13	IPR016024
Domain	WD40	DCAF8 STXBP5 EML6 EIPR1 WDR97 TLE6 CORO6 WDR90 DMWD DYNC1I2	6.58e-05	259	156	10	PF00400
Domain	Ceramidse_alk_C	ASAH2 ASAH2B	6.93e-05	2	156	2	PF17048
Domain	Doc2	DOC2A DOC2B	6.93e-05	2	156	2	IPR014638
Domain	NEUT/ALK_ceramidase_C	ASAH2 ASAH2B	6.93e-05	2	156	2	IPR031331
Domain	Ceramidase_alk	ASAH2 ASAH2B	6.93e-05	2	156	2	IPR006823
Domain	WD40	DCAF8 STXBP5 EML6 EIPR1 WDR97 TLE6 CORO6 WDR90 DMWD DYNC1I2	8.74e-05	268	156	10	SM00320
Domain	WD40_repeat	DCAF8 STXBP5 EML6 EIPR1 WDR97 TLE6 CORO6 WDR90 DMWD DYNC1I2	9.87e-05	272	156	10	IPR001680
Domain	WD_REPEATS_1	DCAF8 STXBP5 EML6 EIPR1 WDR97 TLE6 CORO6 WDR90 DMWD DYNC1I2	1.18e-04	278	156	10	PS00678
Domain	WD_REPEATS_2	DCAF8 STXBP5 EML6 EIPR1 WDR97 TLE6 CORO6 WDR90 DMWD DYNC1I2	1.22e-04	279	156	10	PS50082
Domain	WD_REPEATS_REGION	DCAF8 STXBP5 EML6 EIPR1 WDR97 TLE6 CORO6 WDR90 DMWD DYNC1I2	1.22e-04	279	156	10	PS50294
Domain	WD40_repeat_dom	DCAF8 STXBP5 EML6 EIPR1 WDR97 TLE6 CORO6 WDR90 DMWD DYNC1I2	2.02e-04	297	156	10	IPR017986
Domain	HEAT_REPEAT	MROH2A HEATR5A NCAPG2 DNAAF5 IPO13	2.98e-04	70	156	5	PS50077
Domain	-	DCAF8 STXBP5 EML6 EIPR1 WDR97 TLE6 CORO6 WDR90 DMWD DYNC1I2	5.00e-04	333	156	10	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	DCAF8 STXBP5 EML6 EIPR1 WDR97 TLE6 CORO6 WDR90 DMWD DYNC1I2	5.24e-04	335	156	10	IPR015943
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	DOC2A ANKRD13D TOR4A ATG2A RALGAPA2 DLL1 LARS2 ZZEF1 MAPKAPK5 ADGRA2 KIFC2 FOCAD PIKFYVE ARHGEF40 NUAK1 MTMR14 KLHL36 PI4KA MCM3AP NCAPD2 DISP2 WDR90 NUP188 DMWD ABCC10 SMG6	8.56e-12	1105	160	26	35748872
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SPG11 ATG2A INPP5F BCOR ZZEF1 ADGRA2 TRANK1 NUAK1 NCAPD2 ANKIB1 IPO13 IGSF9 WDR90 NUP188 DAGLA SMG6	3.56e-09	529	160	16	14621295
Pubmed	Nonallelic homologous recombination of the FCGR2/3 locus results in copy number variation and novel chimeric FCGR2 genes with aberrant functional expression.	FCGR2C FCGR2A FCGR2B	9.56e-08	3	160	3	26133275
Pubmed	Functional Fcgamma receptor polymorphisms are associated with human allergy.	FCGR2C FCGR2A FCGR2B	9.56e-08	3	160	3	24586589
Pubmed	T cell-independent B cell activation induces immunosuppressive sialylated IgG antibodies.	FCGR2A FCGR2B IL17RA	3.81e-07	4	160	3	23979161
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	RETREG2 EMC4 PMPCB PIGS FASTKD1 TCIRG1 SPG11 APOB NCAPG2 FOCAD FANCG MCM3AP ANKIB1 IPO13 MACF1 CCAR2 NUP188 ABCC10 CDH16	4.82e-07	1061	160	19	33845483
Pubmed	Copy number variation at the FCGR locus includes FCGR3A, FCGR2C and FCGR3B but not FCGR2A and FCGR2B.	FCGR2C FCGR2A FCGR2B	9.49e-07	5	160	3	19309690
Pubmed	SNPs of Fc-gamma receptor genes and chronic periodontitis.	FCGR2C FCGR2A FCGR2B	9.49e-07	5	160	3	20439936
Pubmed	Copy number, linkage disequilibrium and disease association in the FCGR locus.	FCGR2C FCGR2A FCGR2B	9.49e-07	5	160	3	20508037
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ANKFY1 STXBP5 PHF24 HEATR5A EPG5 FOCAD JMJD6 MCM3AP MACF1 CCAR2 DISP2	3.22e-06	407	160	11	12693553
Pubmed	IL-1α modulates neutrophil recruitment in chronic inflammation induced by hydrocarbon oil.	CCR2 FCGR2A FCGR2B	3.30e-06	7	160	3	21191074
Pubmed	Genetic background of Japanese patients with antineutrophil cytoplasmic antibody-associated vasculitis: association of HLA-DRB1*0901 with microscopic polyangiitis.	FCGR2A FCGR2B TNFRSF1B	5.26e-06	8	160	3	12858454
Pubmed	Genetic predictors of risk and resilience in psychiatric disorders: a cross-disorder genome-wide association study of functional impairment in major depressive disorder, bipolar disorder, and schizophrenia.	ANKFY1 ZZEF1 FCGR2A	5.26e-06	8	160	3	24039173
Pubmed	Gene mapping of the three subunits of the high affinity FcR for IgE to mouse chromosomes 1 and 19.	PARP1 FCGR2A FCGR2B	1.12e-05	10	160	3	2531187
Pubmed	The Immunological Organ Environment Dictates the Molecular and Cellular Pathways of Cytotoxic Antibody Activity.	CCR2 FCGR2A FCGR2B	2.04e-05	12	160	3	31801071
Pubmed	Human FcγRII cytoplasmic domains differentially influence antibody-mediated dengue virus infection.	FCGR2A FCGR2B	2.10e-05	2	160	2	23616574
Pubmed	FcgammaRIIa (CD32) polymorphism and anti-malarial IgG subclass pattern among Fulani and sympatric ethnic groups living in eastern Sudan.	FCGR2A FCGR2B	2.10e-05	2	160	2	19284648
Pubmed	Uptake of human papillomavirus virus-like particles by dendritic cells is mediated by Fcgamma receptors and contributes to acquisition of T cell immunity.	FCGR2A FCGR2B	2.10e-05	2	160	2	17548594
Pubmed	Intraperitoneal Immunization with Cry1Ac Protoxin from Bacillus thuringiensis Provokes Upregulation of Fc-Gamma-II/and Fc-Gamma-III Receptors Associated with IgG in the Intestinal Epithelium of Mice.	FCGR2A FCGR2B	2.10e-05	2	160	2	25904149
Pubmed	Development of self-reactive germinal center B cells and plasma cells in autoimmune Fc gammaRIIB-deficient mice.	FCGR2A FCGR2B	2.10e-05	2	160	2	21078890
Pubmed	FcγRIIB is a T cell checkpoint in antitumor immunity.	FCGR2A FCGR2B	2.10e-05	2	160	2	33616086
Pubmed	Etanercept prevents TNF-α mediated mandibular bone loss in FcγRIIb-/- lupus model.	FCGR2A FCGR2B	2.10e-05	2	160	2	33861790
Pubmed	FcgammaRIIb inhibits allergic lung inflammation in a murine model of allergic asthma.	FCGR2A FCGR2B	2.10e-05	2	160	2	20179765
Pubmed	Respiratory syncytial virus persistence in macrophages upregulates Fcgamma receptors expression.	FCGR2A FCGR2B	2.10e-05	2	160	2	24509813
Pubmed	Genomic structure and promoter analysis of the mouse neutral ceramidase gene.	ASAH2 ASAH2B	2.10e-05	2	160	2	12435403
Pubmed	Antigen-Specific IgG ameliorates allergic airway inflammation via Fcγ receptor IIB on dendritic cells.	FCGR2A FCGR2B	2.10e-05	2	160	2	21477339
Pubmed	Therapeutic inhibition of FcγRIIb signaling targets leukemic stem cells in chronic myeloid leukemia.	FCGR2A FCGR2B	2.10e-05	2	160	2	32684632
Pubmed	Opposite regulation of type II and III receptors for immunoglobulin G in mouse glomerular mesangial cells and in the induction of anti-glomerular basement membrane (GBM) nephritis.	FCGR2A FCGR2B	2.10e-05	2	160	2	11983693
Pubmed	Acute Kidney Injury Induced Lupus Exacerbation Through the Enhanced Neutrophil Extracellular Traps (and Apoptosis) in Fcgr2b Deficient Lupus Mice With Renal Ischemia Reperfusion Injury.	FCGR2A FCGR2B	2.10e-05	2	160	2	34248948
Pubmed	Negative regulation of c-kit-mediated cell proliferation by Fc gamma RIIB.	FCGR2A FCGR2B	2.10e-05	2	160	2	10201978
Pubmed	Antigen-induced oligomerization of the B cell receptor is an early target of Fc gamma RIIB inhibition.	FCGR2A FCGR2B	2.10e-05	2	160	2	20083655
Pubmed	Human IgG Fc receptor (hFcRII; CD32) exists as multiple isoforms in macrophages, lymphocytes and IgG-transporting placental epithelium.	FCGR2C FCGR2B	2.10e-05	2	160	2	2531080
Pubmed	Genomic organization of mouse Fc gamma receptor genes.	FCGR2A FCGR2B	2.10e-05	2	160	2	2138787
Pubmed	Fc receptors: rubor redux.	FCGR2A FCGR2B	2.10e-05	2	160	2	8069908
Pubmed	Genetic control of T-cell proliferative response in mice linked to chromosomes 11 and 15.	FCGR2A FCGR2B	2.10e-05	2	160	2	8824160
Pubmed	Regulation of allograft survival by inhibitory FcγRIIb signaling.	FCGR2A FCGR2B	2.10e-05	2	160	2	23150718
Pubmed	Purification, characterization, molecular cloning, and subcellular distribution of neutral ceramidase of rat kidney.	ASAH2 ASAH2B	2.10e-05	2	160	2	11328816
Pubmed	FcγRIIIA Negatively Impacts Humoral Immune Responses but Not Overall Lung Inflammation in an Ovalbumin-Induced Allergic Asthma Mouse Model.	FCGR2A FCGR2B	2.10e-05	2	160	2	29597194
Pubmed	Antibody-mediated coengagement of FcγRIIb and B cell receptor complex suppresses humoral immunity in systemic lupus erythematosus.	FCGR2A FCGR2B	2.10e-05	2	160	2	21357255
Pubmed	Association of FcγRIIB and FcγRIIA R131H gene polymorphisms with renal involvement in Egyptian systemic lupus erythematosus patients.	FCGR2A FCGR2B	2.10e-05	2	160	2	24366619
Pubmed	Differences in endocytosis mediated by FcγRIIA and FcγRIIB2.	FCGR2A FCGR2B	2.10e-05	2	160	2	21945020
Pubmed	Reversal of immune thrombocytopenia in mice by cross-linking human immunoglobulin G with a high-affinity monoclonal antibody.	FCGR2A FCGR2B	2.10e-05	2	160	2	16925577
Pubmed	Downregulation of neutral ceramidase by gemcitabine: Implications for cell cycle regulation.	ASAH2 ASAH2B	2.10e-05	2	160	2	19345744
Pubmed	FcγRIIb on liver sinusoidal endothelium clears small immune complexes.	FCGR2A FCGR2B	2.10e-05	2	160	2	23053513
Pubmed	Lactosylceramide contributes to mitochondrial dysfunction in diabetes.	ASAH2 ASAH2B	2.10e-05	2	160	2	26900161
Pubmed	A complementary DNA clone for a macrophage-lymphocyte Fc receptor.	FCGR2A FCGR2B	2.10e-05	2	160	2	3024012
Pubmed	Human rhinovirus type 2-antibody complexes enter and infect cells via Fc-gamma receptor IIB1.	FCGR2A FCGR2B	2.10e-05	2	160	2	14990693
Pubmed	Fcgamma receptor IIB-deficient mice develop Goodpasture's syndrome upon immunization with type IV collagen: a novel murine model for autoimmune glomerular basement membrane disease.	FCGR2A FCGR2B	2.10e-05	2	160	2	10704470
Pubmed	Biochemical characterization of murine lymphoid alloantigen Ly-m20.2, a cell surface marker controlled by a gene linked to the Mls locus.	FCGR2A FCGR2B	2.10e-05	2	160	2	3161943
Pubmed	Lipopolysaccharide Impedes Bone Repair in FcγRIIB-Deficient Mice.	FCGR2A FCGR2B	2.10e-05	2	160	2	38069267
Pubmed	Doc2b synchronizes secretion from chromaffin cells by stimulating fast and inhibiting sustained release.	DOC2A DOC2B	2.10e-05	2	160	2	24133251
Pubmed	Autoimmune-prone mice share a promoter haplotype associated with reduced expression and function of the Fc receptor FcgammaRII.	FCGR2A FCGR2B	2.10e-05	2	160	2	10704418
Pubmed	A novel gene derived from a segmental duplication shows perturbed expression in Alzheimer's disease.	ASAH2 ASAH2B	2.10e-05	2	160	2	17334805
Pubmed	Plasmodium curtails autoimmune nephritis via lasting bone marrow alterations, independent of hemozoin accumulation.	FCGR2A FCGR2B	2.10e-05	2	160	2	37539049
Pubmed	Loss of neutral ceramidase protects cells from nutrient- and energy -deprivation-induced cell death.	ASAH2 ASAH2B	2.10e-05	2	160	2	26747710
Pubmed	Activating Fc γ receptors contribute to the antitumor activities of immunoregulatory receptor-targeting antibodies.	FCGR2A FCGR2B	2.10e-05	2	160	2	23897982
Pubmed	CD32B, the human inhibitory Fc-gamma receptor IIB, as a target for monoclonal antibody therapy of B-cell lymphoma.	FCGR2A FCGR2B	2.10e-05	2	160	2	16757681
Pubmed	Doc2: a novel brain protein having two repeated C2-like domains.	DOC2A DOC2B	2.10e-05	2	160	2	7826360
Pubmed	FcγRIIb attenuates TLR4‑mediated NF‑κB signaling in B cells.	FCGR2A FCGR2B	2.10e-05	2	160	2	28849025
Pubmed	Fc receptor beta chain deficiency exacerbates murine arthritis in the anti-type II collagen antibody-induced experimental model.	FCGR2A FCGR2B	2.10e-05	2	160	2	23053716
Pubmed	Fc gamma RIIB regulates nasal and oral tolerance: a role for dendritic cells.	FCGR2A FCGR2B	2.10e-05	2	160	2	15843524
Pubmed	Lupus nephritis progression in FcγRIIB-/-yaa mice is associated with early development of glomerular electron dense deposits and loss of renal DNase I in severe disease.	FCGR2A FCGR2B	2.10e-05	2	160	2	29190833
Pubmed	Otoprotective effects of mouse nerve growth factor in DBA/2J mice with early-onset progressive hearing loss.	CDH23 FSCN2	2.10e-05	2	160	2	28345280
Pubmed	Identification of a high affinity FcgammaRIIA-binding peptide that distinguishes FcgammaRIIA from FcgammaRIIB and exploits FcgammaRIIA-mediated phagocytosis and degradation.	FCGR2A FCGR2B	2.10e-05	2	160	2	18957413
Pubmed	Fcgamma receptor-dependent expansion of a hyperactive monocyte subset in lupus-prone mice.	FCGR2A FCGR2B	2.10e-05	2	160	2	19644866
Pubmed	Comment on "The inhibiting Fc receptor for IgG, FcgammaRIIB, is a modifier of autoimmune susceptibility".	FCGR2A FCGR2B	2.10e-05	2	160	2	21969314
Pubmed	Immunoglobulin E plays an immunoregulatory role in lupus.	FCGR2A FCGR2B	2.10e-05	2	160	2	25267791
Pubmed	FcγRIIB regulates T-cell autoreactivity, ANCA production, and neutrophil activation to suppress anti-myeloperoxidase glomerulonephritis.	FCGR2A FCGR2B	2.10e-05	2	160	2	24869670
Pubmed	Lupus-Associated Immune Complexes Activate Human Neutrophils in an FcγRIIA-Dependent but TLR-Independent Response.	FCGR2A FCGR2B	2.10e-05	2	160	2	30610165
Pubmed	Mutational screening of the TPO and DUOX2 genes in Argentinian children with congenital hypothyroidism due to thyroid dyshormonogenesis.	TPO DUOX2	2.10e-05	2	160	2	35507000
Pubmed	Fc receptors.	FCGR2A FCGR2B	2.10e-05	2	160	2	1910686
Pubmed	DOC2A and DOC2B are sensors for neuronal activity with unique calcium-dependent and kinetic properties.	DOC2A DOC2B	2.10e-05	2	160	2	16515538
Pubmed	Susceptibility quantitative trait loci for pathogenic leucocytosis in SCG/Kj mice, a spontaneously occurring crescentic glomerulonephritis and vasculitis model.	FCGR2A FCGR2B	2.10e-05	2	160	2	24654803
Pubmed	An alloantigen selective for B cells: Ly-17.1.	FCGR2A FCGR2B	2.10e-05	2	160	2	6974691
Pubmed	Functional Role of FcγRIIB in the Regulation of Mesenchymal Stem Cell Function.	FCGR2A FCGR2B	2.10e-05	2	160	2	26941575
Pubmed	Differential role of three major New Zealand Black-derived loci linked with Yaa-induced murine lupus nephritis.	FCGR2A FCGR2B	2.10e-05	2	160	2	15634937
Pubmed	Genetically determined aberrant down-regulation of FcgammaRIIB1 in germinal center B cells associated with hyper-IgG and IgG autoantibodies in murine systemic lupus erythematosus.	FCGR2A FCGR2B	2.10e-05	2	160	2	10508186
Pubmed	Contribution of Fcγ receptors to human respiratory syncytial virus pathogenesis and the impairment of T-cell activation by dendritic cells.	FCGR2A FCGR2B	2.10e-05	2	160	2	26451966
Pubmed	Regulated expression of FcgammaR in human dendritic cells controls cross-presentation of antigen-antibody complexes.	FCGR2A FCGR2B	2.10e-05	2	160	2	17142741
Pubmed	Activatory and inhibitory Fcγ receptors augment rituximab-mediated internalization of CD20 independent of signaling via the cytoplasmic domain.	FCGR2A FCGR2B	2.10e-05	2	160	2	25568316
Pubmed	A lupus-suppressor BALB/c locus restricts IgG2 autoantibodies without altering intrinsic B cell-tolerance mechanisms.	FCGR2A FCGR2B	2.10e-05	2	160	2	18322187
Pubmed	Thymic stromal lymphopoietin transgenic mice develop cryoglobulinemia and hepatitis with similarities to human hepatitis C liver disease.	FCGR2A FCGR2B	2.10e-05	2	160	2	17322382
Pubmed	Defective Fc gamma RII gene expression in macrophages of NOD mice: genetic linkage with up-regulation of IgG1 and IgG2b in serum.	FCGR2A FCGR2B	2.10e-05	2	160	2	8906852
Pubmed	A new mouse cell-surface antigen (Ly-m20) controlled by a gene linked to Mls locus and defined by monoclonal antibodies.	FCGR2A FCGR2B	2.10e-05	2	160	2	6173319
Pubmed	Molecular cloning of the full-length cDNA encoding mouse neutral ceramidase. A novel but highly conserved gene family of neutral/alkaline ceramidases.	ASAH2 ASAH2B	2.10e-05	2	160	2	10753931
Pubmed	CD16/32-specific biotinylated 2.4G2 single-chain Fv complexed with avidin-FITC enhances FITC-specific humoral immune response in vivo in a CD16-dependent manner.	FCGR2A FCGR2B	2.10e-05	2	160	2	19951957
Pubmed	FcγRIIB mediates the inhibitory effect of aggregated α-synuclein on microglial phagocytosis.	FCGR2A FCGR2B	2.10e-05	2	160	2	26342897
Pubmed	FcgammaRIIb balances efficient pathogen clearance and the cytokine-mediated consequences of sepsis.	FCGR2A FCGR2B	2.10e-05	2	160	2	14981111
Pubmed	A serotype 3 pneumococcal capsular polysaccharide-specific monoclonal antibody requires Fcγ receptor III and macrophages to mediate protection against pneumococcal pneumonia in mice.	FCGR2A FCGR2B	2.10e-05	2	160	2	22290146
Pubmed	Monocytes transition to macrophages within the inflamed vasculature via monocyte CCR2 and endothelial TNFR2.	CCR2 TNFRSF1B	2.10e-05	2	160	2	35404389
Pubmed	Neutrophil responsiveness to IgG, as determined by fixed ratios of mRNA levels for activating and inhibitory FcgammaRII (CD32), is stable over time and unaffected by cytokines.	FCGR2A FCGR2B	2.10e-05	2	160	2	16551965
Pubmed	Analysis of a wild mouse promoter variant reveals a novel role for FcγRIIb in the control of the germinal center and autoimmunity.	FCGR2A FCGR2B	2.10e-05	2	160	2	23109709
Pubmed	Augmentation of pulmonary host defense against Pseudomonas by FcgammaRIIA cDNA transfer to the respiratory epithelium.	FCGR2A FCGR2B	2.10e-05	2	160	2	10449433
Pubmed	Spontaneous autoimmune disease in Fc(gamma)RIIB-deficient mice results from strain-specific epistasis.	FCGR2A FCGR2B	2.10e-05	2	160	2	10981970
Pubmed	Broad requirement for terminal sialic acid residues and FcγRIIB for the preventive and therapeutic activity of intravenous immunoglobulins in vivo.	FCGR2A FCGR2B	2.10e-05	2	160	2	24505033
Pubmed	The HLA-DRB1*15:01-restricted Goodpasture's T cell epitope induces GN.	FCGR2A FCGR2B	2.10e-05	2	160	2	23411782
Pubmed	The impact of genetic susceptibility to systemic lupus erythematosus on placental malaria in mice.	FCGR2A FCGR2B	2.10e-05	2	160	2	23675429
Pubmed	Structure and expression of human IgG FcRII(CD32). Functional heterogeneity is encoded by the alternatively spliced products of multiple genes.	FCGR2A FCGR2B	2.10e-05	2	160	2	2529342
Pubmed	Truncated apo B-70.5-containing lipoproteins bind to megalin but not the LDL receptor.	APOB LRP2	2.10e-05	2	160	2	10330424
Pubmed	Modulation of immunoglobulin (Ig)E-mediated systemic anaphylaxis by low-affinity Fc receptors for IgG.	FCGR2A FCGR2B	2.10e-05	2	160	2	10330436
Interaction	TOP3B interactions	DOC2A ANKRD13D TOR4A APOB ATG2A RALGAPA2 DLL1 LARS2 ZZEF1 MAPKAPK5 ADGRA2 KIFC2 FOCAD PIKFYVE LARP4B ARHGEF40 NUAK1 MTMR14 KLHL36 PI4KA MCM3AP NCAPD2 DISP2 WDR90 NUP188 DMWD ABCC10 SMG6	6.89e-06	1470	155	28	int:TOP3B
GeneFamily	WD repeat domain containing	DCAF8 STXBP5 EML6 EIPR1 WDR97 TLE6 CORO6 WDR90 DMWD DYNC1I2	3.52e-06	262	107	10	362
ToppCell	390C-Lymphocytic-ILC-ILC-2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	ASAH2 EIPR1 STIM1 LARP4B ARHGEF40 GALNT8 EPS8L3 ASAH2B	2.21e-07	172	161	8	84d16cd7f618c94888920680bdc9e7130d73fd75
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MROH2A APOB TEX11 TRANK1 NRXN1 LRP2 USH2A UNC79	3.70e-07	184	161	8	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MROH2A APOB TEX11 TRANK1 NRXN1 LRP2 USH2A UNC79	3.70e-07	184	161	8	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MROH2A APOB TEX11 TRANK1 NRXN1 LRP2 USH2A UNC79	3.70e-07	184	161	8	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Classical_Monocyte-Mono_c3-CD14-VCAN\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	DOC2A CDH23 TOR4A PPEF2 ARHGEF40 TNFRSF1B	1.63e-06	99	161	6	a815a887094204de30b299e8907e81ad9a39c016
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPY2R TEX15 ANKRD55 SYT16 DISP2 DLEC1 RAPGEFL1	2.48e-06	166	161	7	548d0d6c0ffd564036ddba78620734220ebb73d7
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPY2R TEX15 ANKRD55 SYT16 DISP2 DLEC1 RAPGEFL1	2.48e-06	166	161	7	80e164a89d22098cabe4a99a78283ba69ea0561e
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPY2R PTCRA LCT ANKRD55 DISP2 CCT8L1P DOC2B	2.58e-06	167	161	7	3dfec2fcc36caa6e394efae5e540a6fa28759977
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPY2R PTCRA LCT ANKRD55 DISP2 CCT8L1P DOC2B	2.58e-06	167	161	7	95b3b5ba3414729f0460a26a0deca48de0cbe33e
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPY2R PTCRA LCT ANKRD55 DISP2 CCT8L1P DOC2B	2.58e-06	167	161	7	9480739587d51e67a281778b9bddd7b5ffc3ad92
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	ANKRD13D ANKFY1 LAMA3 SPG11 STS IPO13 TNFRSF1B	2.79e-06	169	161	7	665b958f4a720ca369a8a0abc7fbe8b6e13c8ce5
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	ANKRD13D ANKFY1 LAMA3 SPG11 STS IPO13 TNFRSF1B	2.79e-06	169	161	7	6614c9851537e4c21b1e45ff0cc3bad07ef9d034
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPO MROH2A LARS2 TRANK1 LRP2 USH2A UNC79	2.79e-06	169	161	7	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	390C-Lymphocytic-ILC\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	CDKN3 ASAH2 EIPR1 ARHGEF40 WDR97 GALNT8 EPS8L3	3.02e-06	171	161	7	70963f79711fe6088d6d01b29206b17ab89e5e73
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma-6\|TCGA-Breast / Sample_Type by Project: Shred V9	STARD8 LRRC32 DLL1 ADGRA2 CILP2 ARHGEF40 USHBP1	5.64e-06	188	161	7	c90669b51e1902fe7726555290c91c92a911df83
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EML6 FOCAD SYT16 FRY NRXN1 CORO6 UNC79	7.40e-06	196	161	7	676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-Z\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TCIRG1 CCR2 FCGR2C FCGR2B PIK3CB TNFRSF1B DSE	7.40e-06	196	161	7	7dff78ff7b2b333680de1c9ca78190770574d796
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EML6 FOCAD SYT16 FRY NRXN1 CORO6 UNC79	7.91e-06	198	161	7	4ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCell	Tracheal-NucSeq-Endothelial-Endothelia_vascular-VE_pulmonary_venous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ACTR8 LRRC32 SHH CDH23 NUAK1 TNFRSF1B DOC2B	8.17e-06	199	161	7	079931e7196719f22a89cfad82f452ec67219ee5
ToppCell	droplet-Lung-nan-3m-Myeloid-dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE4C PTCRA STRA8 PHF24 ANKRD55 IGSF9	1.93e-05	152	161	6	77b319f594d5e4df29034bbf69c7490076f89dd3
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Granulocytic\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KIFC2 USHBP1 TLE6 DAGLA ABCC10 RAPGEFL1	2.15e-05	155	161	6	51f6447945389649d99dcf7603b396195c631ead
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Granulocytic-Mast_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KIFC2 USHBP1 TLE6 DAGLA ABCC10 RAPGEFL1	2.15e-05	155	161	6	23dc71cab28094ca0ac4d2baf4e24871ed107781
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-AT1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC26A5 SHH LAMA3 IRX6 PRSS36 INAVA	2.31e-05	157	161	6	9665a1375cfd8e9b8781c852686591226c0e0d9a
ToppCell	LPS-IL1RA-Hematopoietic_Meg-Ery-Mes-Epi-like\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CDKN3 EMC4 PAQR8 TOR4A BCOR KIFC2	2.31e-05	157	161	6	bd45590da540a557dc8096980a45220fccb99505
ToppCell	LPS-IL1RA-Hematopoietic_Meg-Ery-Mes-Epi-like-Erythroid\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CDKN3 EMC4 PAQR8 TOR4A BCOR KIFC2	2.31e-05	157	161	6	00c9a58b033b8b95b0d838f233dd077b62d8b02a
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-basal_intermediate_\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	COL17A1 LAMA3 DUOX2 PITPNM3 IGSF9 SCART1	2.40e-05	158	161	6	98712ed7e8e65e8c5ff9318cf0e0a04e271a055d
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_1-AT1\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC26A5 SHH LAMA3 PRSS36 INAVA CDH16	2.66e-05	161	161	6	1e17a993126e1f2a25ee7dfbb95a74ccb2a26791
ToppCell	droplet-Lung-3m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ABHD15 STRA8 TCIRG1 ANKRD55 CCR2 UNC79	2.96e-05	164	161	6	cfe07a1ebed8aecb08d0476db71fe314998d54aa
ToppCell	droplet-Lung-3m-Hematologic-myeloid-plasmacytoid_dendritic_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ABHD15 STRA8 TCIRG1 ANKRD55 CCR2 UNC79	2.96e-05	164	161	6	6d331e74efecb4733d87653f86cd67247be05025
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Myeloid-Granulocytic-Neutrophil-Neu_c3-CST7\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	DUSP19 ATG2A SYT16 ARHGEF40 FCGR2A UNC79	3.27e-05	167	161	6	9b9b4cad0b35d121256176600ea4705759c105d3
ToppCell	facs-Lung-nan-3m-Myeloid-Classical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCIRG1 LARS2 CCR2 FCGR2B IL17RA TNFRSF1B	3.50e-05	169	161	6	05b138511039f1255a5f647040b1b9bdf222bd52
ToppCell	facs-Lung-nan-3m-Myeloid-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCIRG1 LARS2 CCR2 FCGR2B IL17RA TNFRSF1B	3.50e-05	169	161	6	bf0a97f53d6e3f9ffeaeae0402b010c49a6cccb7
ToppCell	facs-Marrow-T-cells-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STARD8 STXBP5 CDH23 TRIP13 PIK3CB WDR90	3.74e-05	171	161	6	913bae728b5e653771a27c79a309eb023699f1d0
ToppCell	facs-Marrow-T-cells-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STARD8 STXBP5 CDH23 TRIP13 PIK3CB WDR90	3.74e-05	171	161	6	f28b2336057e353b96a6ff4581ec9fd0ca0789d9
ToppCell	367C-Epithelial_cells-Epithelial-I_(AT1)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	ASAH2 LAMA3 APOB SYT16 IGSF9 INAVA	4.12e-05	174	161	6	edf839d79ac58921f4e788f3b2cb2ae0d6af4b9e
ToppCell	367C-Epithelial_cells-Epithelial-I_(AT1)\|367C / Donor, Lineage, Cell class and subclass (all cells)	ASAH2 LAMA3 APOB SYT16 IGSF9 INAVA	4.12e-05	174	161	6	65539f69100db0b7d90b1b39ee15ab8281f86461
ToppCell	PND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	EML6 SHH LAMA3 TEX15 DAGLA ABCC10	4.25e-05	175	161	6	96219e58dcb327fd27190be78193e7a0d611e62b
ToppCell	PND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	EML6 SHH LAMA3 TEX15 DAGLA ABCC10	4.25e-05	175	161	6	cb974fbebe8cb58c7d3f7defabb4e056f2fee5fa
ToppCell	367C-Myeloid-Dendritic-cDC_proliferating_2\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	CDKN3 PAQR8 TTC34 NCAPG2 NCAPD2 DAGLA	4.25e-05	175	161	6	bde785ff0c854646d7ab8571359e9d69a7bf013f
ToppCell	droplet-Marrow-nan-3m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STARD8 STXBP5 DDX60 PIK3CB SSH2 TNFRSF1B	4.25e-05	175	161	6	cf53a15bfb37b6019e7052ffdf594a9ac040900e
ToppCell	PND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CDKN3 NPY2R TEX15 NCAPD2 LRP2 WDR90	4.53e-05	177	161	6	a68c3688f12aee22f3cb4049c4bccacbacb0fae6
ToppCell	Control-Epithelial_alveolar-AT_1-Differentiating_AT1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC26A5 SHH LAMA3 HEATR5A KIFC2 UTRN	4.53e-05	177	161	6	9af14a056eb6d88c6f11b09f6d4c0d3448d647d5
ToppCell	nucseq-Epithelial-Epithelial_Glandular\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL17A1 DUOX2 STS IGSF9 INAVA EPS8L3	4.82e-05	179	161	6	859cd8ee414ad6207c046ada2e655e49322dd01c
ToppCell	droplet-Lung-21m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CDH23 PPEF2 NCAPG2 PI4KA KCNK6 INAVA	4.82e-05	179	161	6	4f20540bfbcefe0e83812be7ea542e8bb3bf19bc
ToppCell	nucseq-Epithelial-Epithelial_Glandular-Goblet\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL17A1 DUOX2 STS IGSF9 INAVA EPS8L3	4.97e-05	180	161	6	3dc80bc636bf0e6ffc9762853132a9fe59fd1f66
ToppCell	nucseq-Epithelial-Epithelial_Glandular-Goblet-Goblet\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL17A1 DUOX2 STS IGSF9 INAVA EPS8L3	4.97e-05	180	161	6	668a2d8e1d5a390309d5eb62c836f5903144bea9
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC26A5 SHH LAMA3 HEATR5A KIFC2 UTRN	5.13e-05	181	161	6	b45b11428d13950369347e051d4d517efb2bd4fd
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic-Neutrophil-Neu_c1-IL1B\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	ATG2A MTMR14 FCGR2A VNN2 SSH2 DSE	5.29e-05	182	161	6	dc32f8f6a3b13918eb8e93c018f5823d86344080
ToppCell	PCW_05-06-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	MROH2A SHH LAMA3 FRY LRP2 CDH16	5.62e-05	184	161	6	fa4915b0498f3069fd5ef497286445528f75187e
ToppCell	facs-Lung-ENDOMUCIN-18m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC32 LAMA3 DLL1 NUAK1 UTRN DOC2B	5.96e-05	186	161	6	5302399825f213d105ac70b91366a4513b732838
ToppCell	367C-Epithelial_cells-Epithelial-I_(AT1)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	ASAH2 APOB SYT16 IGSF9	6.59e-05	60	161	4	28415d543aaccc74d19e1bb92b7e6fa94f97f8f2
ToppCell	367C-Epithelial_cells-Epithelial-I_(AT1)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	ASAH2 APOB SYT16 IGSF9	6.59e-05	60	161	4	71eba0fbef11cfc2b1c525d5f051530750e4fce9
ToppCell	3'-Distal_airway-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CCR2 FCGR2A VNN2 IL17RA TNFRSF1B DSE	6.71e-05	190	161	6	57800d807785b9d539b47945a0a74631f5e88a06
ToppCell	droplet-Lung-18m-Epithelial-alveolar_epithelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PHF24 LAMA3 TEX11 RTKN LRP2 CDH16	6.91e-05	191	161	6	caed913e7ede9f8ae3af273d1ecf375de6c5e813
ToppCell	3'-Distal_airway-Immune_Myeloid-Myeloid_monocytic-classical_monocyte\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CCR2 FCGR2A VNN2 IL17RA TNFRSF1B DSE	6.91e-05	191	161	6	1c7d31684654ca6a046d8cc816af1fdc42369c57
ToppCell	3'-Distal_airway-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CCR2 FCGR2A VNN2 IL17RA TNFRSF1B DSE	6.91e-05	191	161	6	d60d81d2045c6e624bbc8b17e13a32f7921d969f
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic-Non-classical_Monocyte\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TCIRG1 CCR2 FCGR2A IL17RA SSH2 TNFRSF1B	6.91e-05	191	161	6	47a2afc4102199b4bc76bd01b2967c8016186462
ToppCell	10x3'2.3-week_14-16-Endothelial-stroma-immature_EC\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	PEX11G LRRC32 SLC26A5 DLL1 GALNT8 DOC2B	7.11e-05	192	161	6	5af3b2b38495e925497c48f605d618bbf970965d
ToppCell	facs-Liver-Non-hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STARD8 LRRC32 RALGAPA2 FCGR2B USHBP1 DSE	7.11e-05	192	161	6	2bfac6b3956265205ca47d06888851ed68b65999
ToppCell	facs-Liver-Non-hepatocytes-24m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STARD8 LRRC32 RALGAPA2 FCGR2B USHBP1 DSE	7.11e-05	192	161	6	d525f7f088a53110912600a7c9f6d33b9270d534
ToppCell	Thalamus-Neuronal\|Thalamus / BrainAtlas - Mouse McCarroll V32	ANKRD13D PHF24 RAB3GAP1 TRANK1 DISP2 UNC79	7.31e-05	193	161	6	712a4acd1167e43543950bc819ff11984e6f718d
ToppCell	facs-Liver-Non-hepatocytes-3m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STARD8 LRRC32 LARS2 FCGR2B USHBP1 MACF1	7.31e-05	193	161	6	8084fa0ce61f1f4a728423b6b81df04eaa5af5b6
ToppCell	facs-Liver-Non-hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STARD8 LRRC32 RALGAPA2 FCGR2B USHBP1 DSE	7.53e-05	194	161	6	c8b9551b93a5aed62154b487db90130604a6125c
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)\|390C / Donor, Lineage, Cell class and subclass (all cells)	ANKFY1 LAMA3 SPG11 RTKN STS IPO13	7.53e-05	194	161	6	88db9f9e80c20ff3474f1f6459dcbdc25aec0b6d
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	ANKFY1 LAMA3 SPG11 RTKN STS IPO13	7.53e-05	194	161	6	a71728202493d4858342ea2756ea281cd0d99a3a
ToppCell	distal-Hematologic-Myeloid_Dendritic_Type_2-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FCGR2C FCGR2A FCGR2B KCNK6 TNFRSF1B DSE	7.74e-05	195	161	6	7606b8b40e704bb5447ac57ccf8698794e9c7890
ToppCell	Adult-Immune-monocyte-D231\|Adult / Lineage, Cell type, age group and donor	ANKRD13D CDH23 FCGR2A FCGR2B VNN2 TNFRSF1B	7.74e-05	195	161	6	ea24da6fea1487acb1e56c28c0649858cc0a12bd
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SYN3 LRRC32 LAMA3 RALGAPA2 NUAK1 TNFRSF1B	7.74e-05	195	161	6	d35102f95bb1e419d2df05ff0a01b6c5c923acef
ToppCell	Adult-Immune-monocyte\|Adult / Lineage, Cell type, age group and donor	ANKRD13D CDH23 FCGR2A FCGR2B IL17RA TNFRSF1B	7.96e-05	196	161	6	3ef193c5180de3137daf886492e74fc574bc9767
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c10-MKI67-GZMK\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CDKN3 TRIP13 GTF3C3 FANCG MYG1 NCAPD2	7.96e-05	196	161	6	de70cc301a8cbaedb0a5ea4a6442dcdaa477822d
ToppCell	facs-Liver-Non-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STARD8 LRRC32 RALGAPA2 FCGR2B USHBP1 MACF1	8.19e-05	197	161	6	deefb492b5f0e6014144bd465c4a6ae4206e8739
ToppCell	facs-Liver-Non-hepatocytes-3m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STARD8 LRRC32 RALGAPA2 FCGR2B USHBP1 MACF1	8.19e-05	197	161	6	a6aaa6faea348291023f0bc4b0f83fbc67d91da6
ToppCell	Control-Control-Lymphocyte-T/NK-NK_activated\|Control / Disease, condition lineage and cell class	DOC2A DDX60 TRIP13 TRANK1 MACF1 UTRN	8.42e-05	198	161	6	76d5fe4e5bbe6c73a6ca409b80b5c3924e07cab7
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_hypoxia\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TCIRG1 CCR2 FCGR2C FCGR2B TNFRSF1B DSE	8.42e-05	198	161	6	dc59442e6a5127d3071a036c206732a21e456a17
ToppCell	Somatosensory_Cortex_(S1)-Neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FOCAD SYT16 FRY NRXN1 CORO6 UNC79	8.42e-05	198	161	6	c01091ef18e096d792ea2a7a715764a5b215355f
ToppCell	primary_auditory_cortex_(A1C)-Neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EML6 FOCAD SYT16 FRY NRXN1 UNC79	8.42e-05	198	161	6	6d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EML6 FOCAD SYT16 FRY NRXN1 UNC79	8.42e-05	198	161	6	8ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCell	368C-Endothelial_cells\|368C / Donor, Lineage, Cell class and subclass (all cells)	LRRC32 RALGAPA2 FRY NUAK1 USHBP1 DOC2B	8.42e-05	198	161	6	9a2c2201baee51581733e183065298a97eba4553
ToppCell	facs-Liver-Non-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STARD8 LRRC32 RALGAPA2 FCGR2B USHBP1 MACF1	8.42e-05	198	161	6	f0f1816a0ed3ae8207442602f5cbe4de0382e4b3
ToppCell	Bronchial-NucSeq-Endothelial-Endothelia_vascular-VE_pulmonary_venous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	STARD8 LRRC32 CDH23 DLL1 NUAK1 DOC2B	8.66e-05	199	161	6	3a4deea6e11a0555d27497b7c9983350797aac69
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-Mono\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TCIRG1 CCR2 FCGR2C FCGR2B TNFRSF1B DSE	8.66e-05	199	161	6	87956fcb39c2e3e99622ff05f99267d7621a78fc
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Vein\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	LRRC32 RALGAPA2 DLL1 FRY NUAK1 DOC2B	8.90e-05	200	161	6	7eb366b2c5394af7c77650bde6261e7dac67154e
ToppCell	Neuronal\|World / cells hierarchy compared to all cells using T-Statistic	EML6 FOCAD SYT16 FRY CORO6 UNC79	8.90e-05	200	161	6	48d801219bc771d6c7e151dc88ca4c179988de85
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CCR2 FCGR2C FCGR2B VNN2 TNFRSF1B DSE	8.90e-05	200	161	6	3c9e0dc62d14cc00023f7f18053c1a13085d3413
ToppCell	COVID-19-kidney-Technical/muscle_(EC)\|kidney / Disease (COVID-19 only), tissue and cell type	SYN3 HPSE2 TEX15 NRXN1 USH2A	1.51e-04	139	161	5	64c35411bbe67acb5010dadc4b0b1be0f8b17737
ToppCell	tumor_Lung-Myeloid_cells-Pleural_Mac\|Myeloid_cells / Location, Cell class and cell subclass	LARS2 CCR2 FCGR2B KCNK6 DMWD	1.89e-04	146	161	5	8b2d104fdb0fdb09410450c6c651e1edb00cae44
Drug	H-Na	NUMA1 HPSE2 RTKN LCT FCGR2C FCGR2A FCGR2B	8.27e-07	74	158	7	CID004369271
Drug	Etanercept	FCGR2C FCGR2A FCGR2B TNFRSF1B	2.12e-06	14	158	4	DB00005
Drug	MDL 20,610	FCGR2C FCGR2A FCGR2B	3.25e-06	5	158	3	CID000128209
Drug	TAN-1030A	FCGR2C FCGR2A FCGR2B	6.46e-06	6	158	3	CID009576886
Drug	austin	ADAMTS3 PIKFYVE FCGR2C STS FCGR2A FCGR2B	9.23e-06	70	158	6	CID000430632
Drug	AC1MHTIN	FCGR2C FCGR2A FCGR2B	1.12e-05	7	158	3	CID003011133
Drug	TAN-999	FCGR2C FCGR2A FCGR2B	1.12e-05	7	158	3	CID000130283
Drug	Deferoxamine mesylate [138-14-7]; Up 200; 6uM; PC3; HT_HG-U133A	PDE4C NPY2R COL17A1 SYN3 NUMA1 DUOX2 ADAM30 LCT STS	1.13e-05	200	158	9	3760_UP
Drug	Intravenous Immunoglobulin	FCGR2C FCGR2A FCGR2B	1.79e-05	8	158	3	DB00028
Drug	AC1NSK5W	FCGR2C FCGR2A FCGR2B	2.67e-05	9	158	3	CID005311182
Drug	Palivizumab	FCGR2C FCGR2A FCGR2B	3.80e-05	10	158	3	DB00110
Drug	Denny-Jaffe reagent	FCGR2C FCGR2A FCGR2B	3.80e-05	10	158	3	CID003035979
Drug	Bevacizumab	FCGR2C FCGR2A FCGR2B	5.19e-05	11	158	3	DB00112
Drug	Tositumomab	FCGR2C FCGR2A FCGR2B	5.19e-05	11	158	3	DB00081
Drug	Alemtuzumab	FCGR2C FCGR2A FCGR2B	5.19e-05	11	158	3	DB00087
Drug	Efalizumab	FCGR2C FCGR2A FCGR2B	5.19e-05	11	158	3	DB00095
Drug	Alefacept	FCGR2C FCGR2A FCGR2B	5.19e-05	11	158	3	DB00092
Drug	Cyclobenzaprine hydrochloride [6202-23-9]; Up 200; 12.8uM; MCF7; HT_HG-U133A	DOC2A PTCRA NUMA1 TEX15 BBS9 STS VWA5A LRP2	6.75e-05	195	158	8	3268_UP
Drug	Daclizumab	FCGR2C FCGR2A FCGR2B	6.89e-05	12	158	3	DB00111
Drug	Natalizumab	FCGR2C FCGR2A FCGR2B	6.89e-05	12	158	3	DB00108
Drug	Rituximab	FCGR2C FCGR2A FCGR2B	6.89e-05	12	158	3	DB00073
Drug	Ibritumomab	FCGR2C FCGR2A FCGR2B	6.89e-05	12	158	3	DB00078
Drug	Adalimumab	FCGR2C FCGR2A FCGR2B	6.89e-05	12	158	3	DB00051
Drug	Gemtuzumab ozogamicin	FCGR2C FCGR2A FCGR2B	6.89e-05	12	158	3	DB00056
Drug	Cetuximab	FCGR2C FCGR2A FCGR2B	6.89e-05	12	158	3	DB00002
Disease	malaria (implicated_via_orthology)	FCGR2C FCGR2A FCGR2B	1.24e-05	9	158	3	DOID:12365 (implicated_via_orthology)
Disease	Iodide organification defect	TPO DUOX2	2.85e-05	2	158	2	C2750949
Disease	low affinity immunoglobulin gamma Fc region receptor II-a measurement	FCGR2C FCGR2A FCGR2B	9.69e-05	17	158	3	EFO_0021969
Disease	Myxedema, Congenital	TPO DUOX2	1.70e-04	4	158	2	C1578691
Disease	congenital hypothyroidism (is_implicated_in)	TPO DUOX2	1.70e-04	4	158	2	DOID:0050328 (is_implicated_in)
Disease	Endemic Cretinism	TPO DUOX2	1.70e-04	4	158	2	C0342200
Disease	Adult junctional epidermolysis bullosa (disorder)	COL17A1 LAMA3	2.82e-04	5	158	2	C0268374
Disease	EPIDERMOLYSIS BULLOSA, JUNCTIONAL, LOCALISATA VARIANT (disorder)	COL17A1 LAMA3	2.82e-04	5	158	2	C2608084
Disease	junctional epidermolysis bullosa non-Herlitz type (implicated_via_orthology)	COL17A1 LAMA3	2.82e-04	5	158	2	DOID:0060738 (implicated_via_orthology)
Disease	low affinity immunoglobulin gamma Fc region receptor II-b measurement	FCGR2C FCGR2A FCGR2B	3.18e-04	25	158	3	EFO_0021970
Disease	cortical thickness	CDKN3 ADAMTS3 SHH TTC34 ADGRA2 BBS9 ARHGEF40 NUAK1 TSPAN10 PI4KA MACF1 IGSF9 DLEC1 SSH2 ABCC10 SMG6	3.29e-04	1113	158	16	EFO_0004840
Disease	FEV/FEC ratio	DCAF8 SYN3 LRRC32 SHH CDH23 SLC51B STIM1 FCGR2C FCGR2A FCGR2B TSPAN10 CPT1C ASCC2 DLEC1 SSH2 RAPGEFL1 SMG6	3.30e-04	1228	158	17	EFO_0004713
Disease	rheumatoid arthritis, ACPA-positive rheumatoid arthritis, rheumatoid factor seropositivity measurement	TTC34 ANKRD55 FCGR2A ACSF3	3.69e-04	63	158	4	EFO_0000685, EFO_0007791, EFO_0009459
Disease	Thyroid Dyshormonogenesis 1	TPO DUOX2	4.21e-04	6	158	2	C1848805
Disease	SYSTEMIC LUPUS ERYTHEMATOSUS	FCGR2A FCGR2B	4.21e-04	6	158	2	152700
Disease	Congenital hypothyroidism	TPO DUOX2	4.21e-04	6	158	2	cv:C0010308
Disease	Junctional Epidermolysis Bullosa	COL17A1 LAMA3	4.21e-04	6	158	2	C0079301
Disease	corpus callosum central volume measurement	SHH FANCG NUAK1	4.47e-04	28	158	3	EFO_0010296
Disease	junctional epidermolysis bullosa (is_implicated_in)	COL17A1 LAMA3	5.88e-04	7	158	2	DOID:3209 (is_implicated_in)
Disease	low affinity immunoglobulin gamma Fc region receptor II-a/b measurement	FCGR2A FCGR2B	5.88e-04	7	158	2	EFO_0008211
Disease	Goiter	TPO DUOX2	5.88e-04	7	158	2	C0018021
Disease	arteriovenous malformations of the brain (implicated_via_orthology)	SARS1 PITPNM3	5.88e-04	7	158	2	DOID:0060688 (implicated_via_orthology)
Disease	functional impairment measurement	ZZEF1 FCGR2A	5.88e-04	7	158	2	EFO_0005412
Disease	lymphoid leukemia (is_implicated_in)	FCGR2A FCGR2B	5.88e-04	7	158	2	DOID:1037 (is_implicated_in)
Disease	coronary artery disease	SYN3 ADAMTS3 PTCRA DUOX2 APOB TTC34 ANKRD55 EPG5 PARP1 ACAD11 NRXN1 CORO6 DLEC1 PLG ABCC10 SMG6	7.04e-04	1194	158	16	EFO_0001645
Disease	Intellectual Disability	SRD5A3 DLL1 GTF3C3 PARP1 FRY NRXN1 LRP2 MACF1 DYNC1I2	7.14e-04	447	158	9	C3714756
Disease	serum non-albumin protein measurement	NUMA1 TCIRG1 ANKRD55 PRSS36 FCGR2C FCGR2A FCGR2B CPT1C	7.62e-04	361	158	8	EFO_0004568
Disease	brain measurement, neuroimaging measurement	ADAMTS3 TTC34 BBS9 ACAD11 NUAK1 MACF1 IGSF9 CORO6 SSH2 SMG6	7.97e-04	550	158	10	EFO_0004346, EFO_0004464
Disease	primary bacterial infectious disease (implicated_via_orthology)	SHH DUOX2	1.00e-03	9	158	2	DOID:0050338 (implicated_via_orthology)
Disease	plexin-B2 measurement	FCGR2C FCGR2B	1.00e-03	9	158	2	EFO_0021867
Disease	Disorder of eye	CDH23 BCOR BBS9 FSCN2 PITPNM3 USH2A	1.02e-03	212	158	6	C0015397
Disease	mean platelet volume	STARD8 PTCRA STXBP5 EML6 NUMA1 PAQR8 BCOR STIM1 FANCG FRY TRANK1 PIK3CB PI4KA DSE	1.22e-03	1020	158	14	EFO_0004584
Disease	serum albumin measurement	TCIRG1 ZZEF1 FCGR2C FRY CILP2 FCGR2A FCGR2B CPT1C MACF1 DAGLA	1.38e-03	592	158	10	EFO_0004535
Disease	cortical surface area measurement, neuroimaging measurement	ADAMTS3 TTC34 BBS9 NUAK1 SSH2 SMG6	1.44e-03	227	158	6	EFO_0004346, EFO_0010736
Disease	polymyositis (is_marker_for)	CCR2 TNFRSF1B	1.52e-03	11	158	2	DOID:0080745 (is_marker_for)
Disease	cytochrome p450 3a4 measurement	APOB PIKFYVE	1.52e-03	11	158	2	EFO_0020303
Disease	Systemic lupus erythematosus	FCGR2A FCGR2B	1.52e-03	11	158	2	cv:C0024141
Disease	glomerulonephritis (is_implicated_in)	TPO FCGR2B	1.52e-03	11	158	2	DOID:2921 (is_implicated_in)
Disease	systemic lupus erythematosus (implicated_via_orthology)	FCGR2C FCGR2A FCGR2B	1.59e-03	43	158	3	DOID:9074 (implicated_via_orthology)
Disease	granulins measurement	CDH23 SARS1	1.82e-03	12	158	2	EFO_0008141
Disease	stomach carcinoma (is_implicated_in)	BCOR PARP1	1.82e-03	12	158	2	DOID:5517 (is_implicated_in)
Disease	hearing impairment	SLC26A5 CDH23 FANCG USH2A	1.93e-03	98	158	4	C1384666
Disease	monocyte count	MARS2 RETREG2 STXBP5 CDH23 LCT ANKRD55 CCR2 FCGR2C CILP2 FCGR2B PI4KA IL17RA SSH2 PLG RAPGEFL1 SMG6	1.98e-03	1320	158	16	EFO_0005091
Disease	Autosomal Dominant Myotubular Myopathy	STIM1 MTMR14	2.14e-03	13	158	2	C3661489
Disease	Centronuclear myopathy	STIM1 MTMR14	2.14e-03	13	158	2	C0175709
Disease	X-linked centronuclear myopathy	STIM1 MTMR14	2.14e-03	13	158	2	C0410203
Disease	Myopathy, Centronuclear, 1	STIM1 MTMR14	2.14e-03	13	158	2	C4551952
Disease	Congenital Hypothyroidism	TPO DUOX2	2.14e-03	13	158	2	C0010308
Disease	Congenital Structural Myopathy	STIM1 MTMR14	2.14e-03	13	158	2	C0752282
Disease	Myopathy, Centronuclear, Autosomal Dominant	STIM1 MTMR14	2.49e-03	14	158	2	C1834558
Disease	Tubular Aggregate Myopathy	STIM1 MTMR14	2.49e-03	14	158	2	C0410207
Disease	congenital hypothyroidism (implicated_via_orthology)	TPO DUOX2	2.49e-03	14	158	2	DOID:0050328 (implicated_via_orthology)
Disease	esterified cholesterol measurement, low density lipoprotein cholesterol measurement	ADAMTS3 APOB	2.49e-03	14	158	2	EFO_0004611, EFO_0008589
Disease	autoimmune thrombocytopenic purpura (is_implicated_in)	FCGR2A FCGR2B	2.86e-03	15	158	2	DOID:8924 (is_implicated_in)
Disease	Proteinuria	LRP2 SMG6	2.86e-03	15	158	2	HP_0000093
Disease	Alobar Holoprosencephaly	SHH DLL1	2.86e-03	15	158	2	C0431363
Disease	Autosomal Recessive Centronuclear Myopathy	STIM1 MTMR14	2.86e-03	15	158	2	C3645536
Disease	Pneumonia	CCR2 PARP1 TNFRSF1B	3.06e-03	54	158	3	C0032285
Disease	Lobar Pneumonia	CCR2 PARP1 TNFRSF1B	3.06e-03	54	158	3	C0032300
Disease	Pneumonitis	CCR2 PARP1 TNFRSF1B	3.06e-03	54	158	3	C3714636
Disease	Experimental Lung Inflammation	CCR2 PARP1 TNFRSF1B	3.06e-03	54	158	3	C0887898
Disease	Inherited oocyte maturation defect	TRIP13 TLE6	3.25e-03	16	158	2	cv:CN238505
Disease	response to triptolide, cytotoxicity measurement	SHH ADGRA2	3.25e-03	16	158	2	EFO_0006952, EFO_0007662
Disease	Malaria, susceptibility to	FCGR2A FCGR2B	3.25e-03	16	158	2	cv:C1970028
Disease	–	FCGR2A FCGR2B	3.25e-03	16	158	2	611162
Disease	Lobar Holoprosencephaly	SHH DLL1	3.25e-03	16	158	2	C0431362
Disease	Semilobar Holoprosencephaly	SHH DLL1	3.25e-03	16	158	2	C0751617
Disease	Abnormality of refraction	SYN3 ZZEF1 FRY TSPAN10 GALNT8 ASCC2 CCAR2 DLEC1 UTRN DAGLA	3.49e-03	673	158	10	HP_0000539
Disease	rheumatoid arthritis	TTC34 ANKRD55 CCR2 SYT16 NUAK1 FCGR2A FCGR2B MANEAL	3.56e-03	462	158	8	EFO_0000685
Disease	von Willebrand factor measurement, coronary artery disease	PMPCB STXBP5 APOB SMG6	3.78e-03	118	158	4	EFO_0001645, EFO_0004629
Disease	lupus nephritis (is_implicated_in)	FCGR2A TNFRSF1B	4.12e-03	18	158	2	DOID:0080162 (is_implicated_in)
Disease	migraine disorder, systolic blood pressure	HPSE2 SMG6	4.12e-03	18	158	2	EFO_0006335, MONDO_0005277
Disease	Congenital Fiber Type Disproportion	STIM1 MTMR14	4.12e-03	18	158	2	C0546264
Disease	schizophrenia, inflammatory bowel disease	FCGR2A INAVA	4.12e-03	18	158	2	EFO_0003767, MONDO_0005090
Disease	Brain Ischemia	PARP1 IL17RA TNFRSF1B	4.12e-03	60	158	3	C0007786
Disease	Cerebral Ischemia	PARP1 IL17RA TNFRSF1B	4.12e-03	60	158	3	C0917798
Disease	chylomicron measurement, very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio	SPG11 APOB PLG	4.32e-03	61	158	3	EFO_0008317, EFO_0008596, EFO_0020946
Disease	methadone dose measurement	TEX15 SNX7 UTRN	4.52e-03	62	158	3	EFO_0007907
Disease	acetone measurement	FCGR2B SCART1	4.59e-03	19	158	2	EFO_0010989
Disease	response to methotrexate, neurotoxicity	STIM1 MACF1	4.59e-03	19	158	2	EFO_0011057, GO_0031427
Disease	acne	SYN3 LARS2 DLEC1 INAVA	4.64e-03	125	158	4	EFO_0003894
Disease	angina pectoris	APOB EIPR1 PLG SMG6	4.64e-03	125	158	4	EFO_0003913
Disease	Malaria	FCGR2A FCGR2B	5.08e-03	20	158	2	C0024530
Disease	temporal lobe epilepsy (is_marker_for)	NPY2R SHH	5.08e-03	20	158	2	DOID:3328 (is_marker_for)
Disease	IgA glomerulonephritis (is_marker_for)	SHH TNFRSF1B	5.08e-03	20	158	2	DOID:2986 (is_marker_for)

Protein segments in the cluster

Peptide	Gene	Start	Entry
LSSLEAAAAAWRHQP	USHBP1	126	Q8N6Y0
LVPSDFLSVHLSWLS	CCAR2	251	Q8N163
ILDANLPSHVWSSTL	COL17A1	211	Q9UMD9
SLDLPSHVAVDVWST	SMG6	1046	Q86US8
SIHLALTAWGLEPDE	EPG5	1791	Q9HCE0
LAVSVSDHPDVAWDL	ARHGEF40	516	Q8TER5
ATLWLSEEHPLSLGD	ANKRD13D	361	Q6ZTN6
LTEPVAVSLRHWAEG	ADGRA2	691	Q96PE1
LTAVLADIEVIWSHA	ACTR8	201	Q9H981
LGLSNATVEWHIPDT	ASAH2B	111	P0C7U1
FVANDLDWLLALPHD	ASCC2	61	Q9H1I8
LSDPVHLTVLSEWLV	FCGR2A	111	P12318
SDPVHLTVLSEWLVL	FCGR2B	121	P31994
PLFTAEALLRAHDWD	ANKIB1	251	Q9P2G1
ALEVEWHLLAHPSIT	ACSF3	486	Q4G176
LDVDDRTPLHWAAAA	ANKRD55	261	Q3KP44
LLGSSVEWLHPSDLA	BCOR	1736	Q6W2J9
LSEIADLWNSPTRTH	CDH23	3156	Q9H251
WLPESESLFLASHAS	DMWD	221	Q09019
ALTLVWLPASAVLHE	DISP2	631	A7MBM2
EVAVPWAALLTDHCT	ATG2A	81	Q2TAZ0
PAWSHEVILESFRAL	ABHD15	401	Q6UXT9
LDWELSTIGHPLSDL	ACAD11	241	Q709F0
LDETRDWPESHSLAL	C17orf113	206	A0A1B0GUU1
ACEDPISELHLATTW	RAB3GAP1	271	Q15042
ISELHLATTWPHLTE	RAB3GAP1	276	Q15042
LEKPRIWSLAHTATA	IRX6	346	P78412
ELFLAHILSPWGAEV	PARP1	471	P09874
WLPLHAFQLAVDIDS	NPY2R	281	P49146
LVPAVIFAHLEEAWS	KCNK6	186	Q9Y257
QTPLHLAASWGLEET	ANKFY1	771	Q9P2R3
LAIAVEAVGWAHPDT	PMPCB	296	O75439
TVLELHGALFSWDPV	ABCC10	596	Q5T3U5
SLWDPNITVETLEAH	IL17RA	201	Q96F46
WTNLAHLSLPSEELA	PTCRA	86	Q6ISU1
HLSLPSEELASWEPL	PTCRA	91	Q6ISU1
PLLHANSESGVAVWE	KLHL36	531	Q8N4N3
IHIDPLGTSAWNALV	JMJD6	186	Q6NYC1
EGVLDHPWLNSTEAL	MAPKAPK5	296	Q8IW41
LQELPATIHSASWVA	LAMA3	1506	Q16787
LSIPDFLTHSLNIDW	MTMR14	281	Q8NCE2
SSLVVALHDNPWVCD	LRIT2	191	A6NDA9
QHSWLPARALVEEAL	MYG1	236	Q9HB07
LGLSNATVEWHIPDT	ASAH2	726	Q9NR71
VAWASLDLPSLVAEH	MCM3AP	1336	O60318
EVWGAPVLHLEASSA	LARP4B	61	Q92615
SRTLHWDTDPSVLQL	DYNC1I2	111	Q13409
ALSATISNPEHLTEW	DDX60	916	Q8IY21
EDTLSLHIRAVGPWT	DUOX2	1326	Q9NRD8
FWGLPSLHSESLEAI	C9orf131	196	Q5VYM1
SDPVHLTVLSEWLVL	FCGR2C	121	P31995
LTDIPGFEASHIWIS	OR51Q1	16	Q8NH59
TWADLVHPDAQDLLD	PDE4C	611	Q08493
RASEVPSLTALHTLW	TPO	396	P07202
PVLATSGLDHDVKIW	DCAF8	491	Q5TAQ9
LATWLKETSAPELVH	EPS8L3	301	Q8TE67
WHTIDADAPELSHVL	PI4KA	1596	P42356
HVGIVLNSDWAEPLS	LCT	596	P09848
WDEVPLAHSLVGFAT	DSE	146	Q9UL01
NHRLPAAESLAVDWV	LRP2	3266	P98164
SHEDALWSLPLYLES	FANCG	581	O15287
ATLLADTPVNDGAWH	NRXN1	101	Q9ULB1
LQLDPSIIHDGWLDF	HPSE2	81	Q8WWQ2
VVADADARHWLQLSP	RALGAPA2	881	Q2PPJ7
EIWHISASPADRGVL	EIPR1	66	Q53HC9
LGWEETVDAAISHLL	BBS9	766	Q3SYG4
VLADLSALEAHWSTL	MACF1	1186	Q9UPN3
VLPAAEFHGLWDSLV	TRIP13	126	Q15645
LSHLPAWTQAVSLEV	LRRC32	526	Q14392
EPAAEWSVLLGVHSQ	PRSS36	96	Q5K4E3
EAEHSALNPLRAVWL	SRD5A3	6	Q9H8P0
FAEAEALPWASTHSL	PAQR8	96	Q8TEZ7
EEHLAALTAAPRGTW	CPT1C	376	Q8TCG5
LEDDLAWQSLIHPDS	PIKFYVE	266	Q9Y2I7
DTNILAPATWSAHEL	ADAM30	326	Q9UKF2
AEARSEILAHWSPAK	APOB	1131	P04114
LVAPGAVVEWHETSL	ADAMTS3	101	O15072
SPDVQTWALHSLSLI	HEATR5A	946	Q86XA9
PDAALERWHTLTSEL	DOC2A	376	Q14183
ERWHTLTSELPGAVL	DOC2B	396	Q14184
WPGTFSLIIEALHTD	DLL1	116	O00548
DALPQAWIDLHDVTA	GALNT8	336	Q9NY28
AHDPLVEALVTEAWR	FASTKD1	131	Q53R41
LPSHALEDEGWAAAA	CDC42EP4	276	Q9H3Q1
FLITLPLWAHSAANE	CCR2	91	P41597
LVTGHTAPVLDIDWC	CORO6	76	Q6QEF8
DSYLTSPEAWAHLLT	MANEAL	271	Q5VSG8
RLWTHPSDLTIALSA	DAGLA	581	Q9Y4D2
IWPAHSDITDVNAAS	EML6	1186	Q6ZMW3
LLPTHASDWLAFIEP	EMC4	156	Q5J8M3
VVDHSVREDWALHLP	FRY	1651	Q5TBA9
LPALCHDITDWVVGT	DNAAF5	361	Q86Y56
EDEQTPIHISWLSLS	CDKN3	21	Q16667
ELDHTVDSLTWNLTP	DLEC1	266	Q9Y238
WALIDCDPSLIDATH	INPP5F	621	Q9Y2H2
LDDWALHREDPLSSL	INAVA	176	Q3KP66
FTIGALSEWLADHPV	IPO13	511	O94829
VAGLTHWDVPNLETL	KIFC2	561	Q96AC6
STWVSLEPIHLAENL	CDH16	236	O75309
VVAWADHTAPLLLGL	FOCAD	1681	Q5VW36
SDWAAAVESVLHLGL	PPEF2	591	O14830
LLSWVNSLHVADPVE	NUMA1	11	Q14980
EDASPWNHSILALAA	SLC51B	31	Q86UW2
SHLAEVWLAVSENVP	MROH2A	1171	A6NES4
AAALADHLPEDKWSA	PIGS	201	Q96S52
FATAVSPAELWTVHL	FSCN2	121	O14926
HDAPEESLRAWVAAT	FAN1	891	Q9Y2M0
HDLTLASHEENPAWL	RTKN	276	Q9BST9
TSEQPIAALHRDEWL	SARS1	271	P49591
PRILLVIDDAHTDWS	SYN3	91	O14994
LSAVALHLSWSVPEK	USH2A	3601	O75445
WLPVLHRVAAAETAK	UTRN	3051	P46939
QIGTWLLDSEALHPL	SHH	441	Q15465
WASDDRKLPHVLSSI	SYT16	126	Q17RD7
LAPHVTSEIWAGLAL	LARS2	791	Q15031
PALWELLFHSIHDAV	SLC26A5	696	P58743
WEKPLHSLVTAAALN	RETREG2	76	Q8NC44
LWEAESHAASRPNII	STS	16	P08842
ELEHPAAWLLREAAQ	CCT8L1P	81	A6NM43
HDSESPLLARIIDWH	NUAK1	321	O60285
DIILHSWSSFPDELE	PIK3CB	456	P42338
VSSLSLHWVNDLPRA	NDUFAF5	156	Q5TEU4
LISPEWVLTAAHCLE	PLG	611	P00747
GIHSLVAALNIDPSW	STIM1	446	Q13586
GALVSALADDTLHLW	STXBP5	111	Q5T5C0
GHIEWPDFLSHESLL	PHF24	261	Q9UPV7
PIHILWSASEEDLVD	SNX7	226	Q9UNH6
WLAAAQAATLLLPDE	STARD8	676	Q92502
ASLPWRLQTALEEHL	SLFNL1	106	Q499Z3
EAALPIVSAAISHLW	STRA8	171	Q7Z7C7
ELIAAHLNPSDTEEW	GTF3C3	206	Q9Y5Q9
TDWALPSAVGERVHL	CILP2	101	Q8IUL8
FEHLAPVLVAAVSLW	NCAPD2	251	Q15021
HILELVDNWLPTEHA	NCAPG2	721	Q86XI2
LTLAGHWLAQEDVVP	SPG11	1776	Q96JI7
LSNLADLANAVHWLP	PEX11G	186	Q96HA9
VLPLLTAIEFHSAWA	VNN2	241	O95498
PWAQLEASDIHTAAA	WDR90	316	Q96KV7
VLPLWSDTLIHLDGD	SSH2	141	Q76I76
LHEQDLGPALEWAVS	RMND5B	166	Q96G75
TDWSHSQLLDLGPID	WDR97	1471	A6NE52
WALLRHTLNPEETSS	NUP188	326	Q5SRE5
LESFLESVWELPHLE	TEX11	756	Q8IYF3
PLCATHWDIADATVL	SCART1	351	Q4G0T1
SLQPVVEDVSLSWHL	VWA5A	461	O00534
VDAPWLGTVLHVALE	MARS2	501	Q96GW9
DWVSLAVPVGAAHLL	IGSF9	556	Q9P2J2
SESWAIDPVLHNLTE	TAS1R2	301	Q8TE23
LVFLEWHEAPTIAVA	TAS1R2	556	Q8TE23
WHEAPTIAVALLAAL	TAS1R2	561	Q8TE23
APWHLRNVLSDSVES	PITPNM3	16	Q9BZ71
LDQHSLIPATASAVW	MTHFD2L	181	Q9H903
AVLSREHPLWQAAAI	TOR4A	346	Q9NXH8
VVALWGPLQDSLEHT	TSPAN10	171	Q9H1Z9
HCPEAVEATWVLSLA	ZZEF1	2341	O43149
DHWPSLVQEATTEAL	TTC37	1461	Q6PGP7
AVGLELWAAAHALPA	TNFRSF1B	11	P20333
SGEALPLDHTLETWI	ZFAND1	221	Q8TCF1
LDHLALEWQITPSFE	TEX15	321	Q9BXT5
DLDICTIIPHLSTWD	TRANK1	426	O15050
THWVATEVLLCEAPG	RAPGEFL1	476	Q9UHV5
AWTAVESGLLVDPDH	TTC34	531	A8MYJ7
IDPIWSLAANHLSFL	TCIRG1	516	Q13488
LASVSVWDLAAPSLH	TLE6	356	Q9H808
GDHSEWLIDVLLPQA	UNC79	351	Q9P2D8
PWLLLGSQDAAHDLD	DUSP19	71	Q8WTR2
DSVPLIWSQLEHADV	GARIN5B	231	Q8N5Q1