Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	retinoic acid-responsive element binding	RXRA RXRB	1.55e-04	7	55	2	GO:0044323
GeneOntologyMolecularFunction	extracellular matrix structural constituent	SRPX2 ADIPOQ MUC5AC FBN3 HAPLN1	1.67e-04	188	55	5	GO:0005201
GeneOntologyMolecularFunction	benzodiazepine receptor activity	GABRA1 GABRA4	4.03e-04	11	55	2	GO:0008503
GeneOntologyMolecularFunction	growth factor binding	SRPX2 RPL37 REG3G REG3A	8.97e-04	156	55	4	GO:0019838
GeneOntologyMolecularFunction	GABA-gated chloride ion channel activity	GABRA1 GABRA4	1.11e-03	18	55	2	GO:0022851
GeneOntologyMolecularFunction	nuclear vitamin D receptor binding	RXRA RXRB	1.11e-03	18	55	2	GO:0042809
GeneOntologyMolecularFunction	GABA-A receptor activity	GABRA1 GABRA4	1.24e-03	19	55	2	GO:0004890
GeneOntologyMolecularFunction	peptidoglycan binding	REG3G REG3A	1.24e-03	19	55	2	GO:0042834
GeneOntologyMolecularFunction	oligosaccharide binding	REG3G REG3A	1.37e-03	20	55	2	GO:0070492
GeneOntologyMolecularFunction	GABA receptor activity	GABRA1 GABRA4	1.66e-03	22	55	2	GO:0016917
GeneOntologyMolecularFunction	nuclear steroid receptor activity	RXRA RXRB	2.15e-03	25	55	2	GO:0003707
GeneOntologyMolecularFunction	Notch binding	SNED1 DNER	2.50e-03	27	55	2	GO:0005112
GeneOntologyBiologicalProcess	skeletal muscle tissue regeneration	SOX15 TMEM182 EYS PLAU	1.85e-05	59	55	4	GO:0043403
GeneOntologyBiologicalProcess	detection of monosaccharide stimulus	REG3G REG3A	2.09e-05	3	55	2	GO:0034287
GeneOntologyBiologicalProcess	detection of hexose stimulus	REG3G REG3A	2.09e-05	3	55	2	GO:0009732
GeneOntologyBiologicalProcess	detection of carbohydrate stimulus	REG3G REG3A	2.09e-05	3	55	2	GO:0009730
GeneOntologyBiologicalProcess	mitochondrial mRNA catabolic process	PDE12 SUPV3L1	2.09e-05	3	55	2	GO:0000958
GeneOntologyBiologicalProcess	positive regulation of detection of glucose	REG3G REG3A	2.09e-05	3	55	2	GO:2000972
GeneOntologyBiologicalProcess	regulation of detection of glucose	REG3G REG3A	2.09e-05	3	55	2	GO:2000970
GeneOntologyBiologicalProcess	detection of glucose	REG3G REG3A	2.09e-05	3	55	2	GO:0051594
GeneOntologyBiologicalProcess	mitochondrial RNA catabolic process	PDE12 SUPV3L1	1.04e-04	6	55	2	GO:0000957
GeneOntologyBiologicalProcess	positive regulation of vitamin D receptor signaling pathway	RXRA RXRB	1.04e-04	6	55	2	GO:0070564
GeneOntologyBiologicalProcess	tissue regeneration	SOX15 TMEM182 EYS PLAU	1.41e-04	99	55	4	GO:0042246
GeneOntologyBiologicalProcess	response to symbiont	REG3G REG3A	1.93e-04	8	55	2	GO:0009608
GeneOntologyBiologicalProcess	response to symbiotic bacterium	REG3G REG3A	1.93e-04	8	55	2	GO:0009609
GeneOntologyBiologicalProcess	regulation of vitamin D receptor signaling pathway	RXRA RXRB	3.10e-04	10	55	2	GO:0070562
GeneOntologyBiologicalProcess	negative regulation of keratinocyte differentiation	REG3G REG3A	3.10e-04	10	55	2	GO:0045617
GeneOntologyBiologicalProcess	antiviral innate immune response	TRAF6 PDE12 HCFC2	4.50e-04	56	55	3	GO:0140374
GeneOntologyBiologicalProcess	regulation of keratinocyte proliferation	KLF9 REG3G REG3A	4.50e-04	56	55	3	GO:0010837
GeneOntologyBiologicalProcess	vitamin D receptor signaling pathway	RXRA RXRB	4.53e-04	12	55	2	GO:0070561
GeneOntologyBiologicalProcess	negative regulation of cellular response to oxidative stress	REG3G REG3A	4.53e-04	12	55	2	GO:1900408
GeneOntologyBiologicalProcess	negative regulation of inflammatory response to wounding	REG3G REG3A	5.34e-04	13	55	2	GO:0106015
GeneOntologyBiologicalProcess	cellular response to interleukin-12	TYK2 SIRPB1	5.34e-04	13	55	2	GO:0071349
GeneOntologyCellularComponent	extracellular matrix	SNED1 EYS SRPX2 ADIPOQ CELA2A REG3G REG3A MUC5AC FBN3 HAPLN1	7.07e-06	656	55	10	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	SNED1 EYS SRPX2 ADIPOQ CELA2A REG3G REG3A MUC5AC FBN3 HAPLN1	7.26e-06	658	55	10	GO:0030312
GeneOntologyCellularComponent	extrinsic component of cytoplasmic side of plasma membrane	TYK2 TRAF6 GNAL	4.33e-04	56	55	3	GO:0031234
GeneOntologyCellularComponent	collagen-containing extracellular matrix	EYS SRPX2 ADIPOQ CELA2A REG3G REG3A HAPLN1	4.58e-04	530	55	7	GO:0062023
GeneOntologyCellularComponent	GABA-A receptor complex	GABRA1 GABRA4	1.13e-03	19	55	2	GO:1902711
GeneOntologyCellularComponent	GABA receptor complex	GABRA1 GABRA4	1.38e-03	21	55	2	GO:1902710
Domain	hEGF	SNED1 EYS DNER FBN3	1.31e-06	28	55	4	PF12661
Domain	GABAAa_rcpt	GABRA1 GABRA4	1.27e-04	6	55	2	IPR001390
Domain	EGF_Ca-bd_CS	SNED1 EYS DNER FBN3	1.90e-04	97	55	4	IPR018097
Domain	EGF_CA	SNED1 EYS DNER FBN3	2.06e-04	99	55	4	PS01187
Domain	ASX_HYDROXYL	SNED1 EYS DNER FBN3	2.14e-04	100	55	4	PS00010
Domain	EGF-type_Asp/Asn_hydroxyl_site	SNED1 EYS DNER FBN3	2.68e-04	106	55	4	IPR000152
Domain	Retinoid-X_rcpt/HNF4	RXRA RXRB	3.77e-04	10	55	2	IPR000003
Domain	EGF_CA	SNED1 EYS DNER FBN3	4.57e-04	122	55	4	SM00179
Domain	Fol_N	SNED1 DNER	4.60e-04	11	55	2	IPR003645
Domain	FOLN	SNED1 DNER	4.60e-04	11	55	2	SM00274
Domain	EGF-like_Ca-bd_dom	SNED1 EYS DNER FBN3	4.86e-04	124	55	4	IPR001881
Domain	EGF	SNED1 EYS DNER FBN3	5.16e-04	126	55	4	PF00008
Domain	CCP	SNED1 SRPX2 PAPPA	5.39e-04	54	55	3	SM00032
Domain	SUSHI	SNED1 SRPX2 PAPPA	6.00e-04	56	55	3	PS50923
Domain	EGF_3	SNED1 EYS DNER PLAU FBN3	6.30e-04	235	55	5	PS50026
Domain	EGF	SNED1 EYS DNER PLAU FBN3	6.30e-04	235	55	5	SM00181
Domain	Sushi_SCR_CCP_dom	SNED1 SRPX2 PAPPA	6.32e-04	57	55	3	IPR000436
Domain	EGF-like_dom	SNED1 EYS DNER PLAU FBN3	8.17e-04	249	55	5	IPR000742
Domain	EGF_1	SNED1 EYS DNER PLAU FBN3	9.09e-04	255	55	5	PS00022
Domain	EGF-like_CS	SNED1 EYS DNER PLAU FBN3	1.01e-03	261	55	5	IPR013032
Domain	EGF_2	SNED1 EYS DNER PLAU FBN3	1.08e-03	265	55	5	PS01186
Domain	Kringle	ROR1 PLAU	1.13e-03	17	55	2	IPR000001
Domain	Kringle_CS	ROR1 PLAU	1.13e-03	17	55	2	IPR018056
Domain	KRINGLE_2	ROR1 PLAU	1.13e-03	17	55	2	PS50070
Domain	Kringle	ROR1 PLAU	1.13e-03	17	55	2	PF00051
Domain	KRINGLE_1	ROR1 PLAU	1.13e-03	17	55	2	PS00021
Domain	KR	ROR1 PLAU	1.13e-03	17	55	2	SM00130
Domain	KAZAL_1	FSTL5 SPINK5	1.26e-03	18	55	2	PS00282
Domain	Kazal_1	FSTL5 SPINK5	1.89e-03	22	55	2	PF00050
Domain	GABAA/Glycine_rcpt	GABRA1 GABRA4	2.07e-03	23	55	2	IPR006028
Domain	-	REG3G REG3A HAPLN1	2.93e-03	97	55	3	3.10.100.10
Domain	C-type_lectin-like/link	REG3G REG3A HAPLN1	3.10e-03	99	55	3	IPR016186
Domain	CTDL_fold	REG3G REG3A HAPLN1	3.86e-03	107	55	3	IPR016187
Domain	Kringle-like	ROR1 PLAU	3.99e-03	32	55	2	IPR013806
Domain	Kazal_2	FSTL5 SPINK5	5.03e-03	36	55	2	PF07648
Domain	C-type_lectin_CS	REG3G REG3A	7.12e-03	43	55	2	IPR018378
Domain	Neurotransmitter_ion_chnl_CS	GABRA1 GABRA4	7.77e-03	45	55	2	IPR018000
Domain	Neur_chan_memb	GABRA1 GABRA4	8.11e-03	46	55	2	PF02932
Domain	zf-C4	RXRA RXRB	8.11e-03	46	55	2	PF00105
Domain	Znf_hrmn_rcpt	RXRA RXRB	8.11e-03	46	55	2	IPR001628
Domain	Nuclear_hrmn_rcpt	RXRA RXRB	8.11e-03	46	55	2	IPR001723
Domain	NUCLEAR_REC_DBD_2	RXRA RXRB	8.11e-03	46	55	2	PS51030
Domain	NUCLEAR_REC_DBD_1	RXRA RXRB	8.11e-03	46	55	2	PS00031
Domain	KAZAL	FSTL5 SPINK5	8.11e-03	46	55	2	SM00280
Domain	ZnF_C4	RXRA RXRB	8.11e-03	46	55	2	SM00399
Domain	Neur_chan_LBD	GABRA1 GABRA4	8.46e-03	47	55	2	PF02931
Domain	-	RXRA RXRB	8.46e-03	47	55	2	1.10.565.10
Domain	NEUROTR_ION_CHANNEL	GABRA1 GABRA4	8.46e-03	47	55	2	PS00236
Domain	Neurotrans-gated_channel_TM	GABRA1 GABRA4	8.46e-03	47	55	2	IPR006029
Domain	-	GABRA1 GABRA4	8.46e-03	47	55	2	2.70.170.10
Domain	Neur_channel	GABRA1 GABRA4	8.46e-03	47	55	2	IPR006201
Domain	Neur_chan_lig-bd	GABRA1 GABRA4	8.46e-03	47	55	2	IPR006202
Domain	HOLI	RXRA RXRB	8.81e-03	48	55	2	SM00430
Domain	Nucl_hrmn_rcpt_lig-bd	RXRA RXRB	8.81e-03	48	55	2	IPR000536
Domain	Hormone_recep	RXRA RXRB	8.81e-03	48	55	2	PF00104
Pathway	WP_VITAMIN_A_AND_CAROTENOID_METABOLISM	BCO2 RXRA RXRB ADH4	9.32e-06	43	44	4	M39554
Pathway	WP_RETINOL_METABOLISM	BCO2 RXRA RXRB ADH4	1.02e-05	44	44	4	MM15851
Pathway	KEGG_MEDICUS_VARIANT_PAX8_PPARG_FUSION_TO_PPARG_MEDIATED_TRANSCRIPTION	RXRA RXRB	9.46e-05	5	44	2	M49023
Pathway	REACTOME_NR1H2_NR1H3_REGULATE_GENE_EXPRESSION_LINKED_TO_GLUCONEOGENESIS	RXRA RXRB	9.46e-05	5	44	2	M29812
Pathway	REACTOME_NR1H2_NR1H3_REGULATE_GENE_EXPRESSION_TO_LIMIT_CHOLESTEROL_UPTAKE	RXRA RXRB	9.46e-05	5	44	2	M29791
Pathway	REACTOME_NR1H2_NR1H3_REGULATE_GENE_EXPRESSION_LINKED_TO_TRIGLYCERIDE_LIPOLYSIS_IN_ADIPOSE	RXRA RXRB	9.46e-05	5	44	2	M29792
Pathway	REACTOME_NR1H2_NR1H3_REGULATE_GENE_EXPRESSION_TO_CONTROL_BILE_ACID_HOMEOSTASIS	RXRA RXRB	1.42e-04	6	44	2	MM15663
Pathway	WP_VITAMIN_A1_AND_A5X_PATHWAYS	RXRA RXRB	1.42e-04	6	44	2	M48097
Pathway	WP_NUCLEAR_RECEPTORS	ROR1 RXRA RXRB	2.22e-04	38	44	3	M39657
Pathway	WP_NUCLEAR_RECEPTORS	ROR1 RXRA RXRB	2.22e-04	38	44	3	MM15865
Pathway	BIOCARTA_VOBESITY_PATHWAY	ADIPOQ RXRA	2.63e-04	8	44	2	MM1542
Pathway	BIOCARTA_VOBESITY_PATHWAY	ADIPOQ RXRA	2.63e-04	8	44	2	M22017
Pathway	REACTOME_SIGNALING_BY_RETINOIC_ACID	RXRA RXRB ADH4	3.21e-04	43	44	3	M27443
Pathway	BIOCARTA_FLUMAZENIL_PATHWAY	GABRA1 GABRA4	3.38e-04	9	44	2	M22034
Pathway	REACTOME_NR1H2_NR1H3_REGULATE_GENE_EXPRESSION_TO_CONTROL_BILE_ACID_HOMEOSTASIS	RXRA RXRB	3.38e-04	9	44	2	M29809
Pathway	REACTOME_NR1H2_NR1H3_REGULATE_GENE_EXPRESSION_LINKED_TO_LIPOGENESIS	RXRA RXRB	3.38e-04	9	44	2	M29789
Pathway	KEGG_MEDICUS_REFERENCE_THYROID_HORMONE_SIGNALING_PATHWAY	RXRA RXRB	3.38e-04	9	44	2	M47629
Pathway	WP_VITAMIN_D_METABOLISM	RXRA RXRB	4.22e-04	10	44	2	M39352
Pathway	BIOCARTA_GABA_PATHWAY	GABRA1 GABRA4	4.22e-04	10	44	2	MM1401
Pathway	BIOCARTA_GABA_PATHWAY	GABRA1 GABRA4	4.22e-04	10	44	2	M477
Pathway	REACTOME_SIGNALING_BY_RETINOIC_ACID	RXRA RXRB ADH4	4.73e-04	49	44	3	MM15186
Pathway	REACTOME_NR1H2_AND_NR1H3_MEDIATED_SIGNALING	RXRA RXRB	7.27e-04	13	44	2	MM15622
Pathway	REACTOME_GABA_RECEPTOR_ACTIVATION	GNAL GABRA1 GABRA4	8.57e-04	60	44	3	M976
Pathway	REACTOME_GABA_RECEPTOR_ACTIVATION	GNAL GABRA1 GABRA4	8.57e-04	60	44	3	MM15708
Pathway	WP_PPAR_SIGNALING	ADIPOQ RXRA RXRB	1.18e-03	67	44	3	M39553
Pathway	KEGG_ADIPOCYTOKINE_SIGNALING_PATHWAY	ADIPOQ RXRA RXRB	1.18e-03	67	44	3	M10462
Pathway	KEGG_PPAR_SIGNALING_PATHWAY	ADIPOQ RXRA RXRB	1.29e-03	69	44	3	M13088
Pathway	WP_PPAR_SIGNALING_PATHWAY	ADIPOQ RXRA RXRB	1.52e-03	73	44	3	MM15995
Pathway	WP_NONGENOMIC_ACTIONS_OF_125_DIHYDROXYVITAMIN_D3	TYK2 RXRA RXRB	1.64e-03	75	44	3	M39568
Pathway	REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS	ST3GAL3 MUC5AC	1.93e-03	21	44	2	MM15706
Pubmed	A dynamic expression survey identifies transcription factors relevant in mouse digestive tract development.	SOX15 HOXC8 REG3G REG3A PLAU RXRA RXRB	7.67e-10	118	55	7	16971476
Pubmed	Expression analysis of the regenerating gene (Reg) family members Reg-IIIβ and Reg-IIIγ in the mouse during development.	REG3G REG3A MUC5AC	4.46e-07	10	55	3	21681751
Pubmed	Dlx6 regulates molecular properties of the striatum and central nucleus of the amygdala.	IKZF1 DLX5 GNAL	1.06e-06	13	55	3	21452241
Pubmed	RXR alpha mutant mice establish a genetic basis for vitamin A signaling in heart morphogenesis.	RXRA RXRB	2.46e-06	2	55	2	7926783
Pubmed	Regulation of pancreatitis-associated protein (HIP/PAP) mRNA levels in mouse pancreas and small intestine.	REG3G REG3A	2.46e-06	2	55	2	8795446
Pubmed	Pancreatic islet immunoreactivity to the Reg protein INGAP.	REG3G REG3A	2.46e-06	2	55	2	17998566
Pubmed	Regenerating islet-derived 3-alpha is a biomarker of gastrointestinal graft-versus-host disease.	REG3G REG3A	2.46e-06	2	55	2	21979939
Pubmed	HIP/PAP protects against bleomycin-induced lung injury and inflammation and subsequent fibrosis in mice.	REG3G REG3A	2.46e-06	2	55	2	32352211
Pubmed	Tyk2 mediates effects of urokinase on human vascular smooth muscle cell growth.	TYK2 PLAU	2.46e-06	2	55	2	17548050
Pubmed	Retinoid-X-receptors (α/β) in melanocytes modulate innate immune responses and differentially regulate cell survival following UV irradiation.	RXRA RXRB	2.46e-06	2	55	2	24810760
Pubmed	Reg3β is associated with cardiac inflammation and provides prognostic information in patients with acute coronary syndrome.	REG3G REG3A	2.46e-06	2	55	2	29544958
Pubmed	Limited degradation of retinoid X receptor by calpain.	RXRA RXRB	2.46e-06	2	55	2	8780715
Pubmed	Nuclear hormone retinoid X receptor (RXR) negatively regulates the glucose-stimulated insulin secretion of pancreatic ß-cells.	RXRA RXRB	2.46e-06	2	55	2	20798333
Pubmed	Dysfunction of the RAR/RXR signaling pathway in the forebrain impairs hippocampal memory and synaptic plasticity.	RXRA RXRB	2.46e-06	2	55	2	22316320
Pubmed	Targeted expression of islet neogenesis associated protein to beta cells enhances glucose tolerance and confers resistance to streptozotocin-induced hyperglycemia.	REG3G REG3A	2.46e-06	2	55	2	21187123
Pubmed	Regulation of C-type lectin antimicrobial activity by a flexible N-terminal prosegment.	REG3G REG3A	2.46e-06	2	55	2	19095652
Pubmed	Symbiotic bacteria direct expression of an intestinal bactericidal lectin.	REG3G REG3A	2.46e-06	2	55	2	16931762
Pubmed	Genetic variant of RXR involved in the vitamin D metabolic pathway was linked to HCV infection outcomes among a high-risk Chinese population.	RXRA RXRB	2.46e-06	2	55	2	33246082
Pubmed	Intestinal REG3 Lectins Protect against Alcoholic Steatohepatitis by Reducing Mucosa-Associated Microbiota and Preventing Bacterial Translocation.	REG3G REG3A	2.46e-06	2	55	2	26867181
Pubmed	Endogenous retinoid X receptor ligands in mouse hematopoietic cells.	RXRA RXRB	2.46e-06	2	55	2	29089448
Pubmed	Salmonella-induced mucosal lectin RegIIIβ kills competing gut microbiota.	REG3G REG3A	2.46e-06	2	55	2	21694778
Pubmed	Recombinant Reg3α protein protects against experimental acute pancreatitis in mice.	REG3G REG3A	2.46e-06	2	55	2	26683606
Pubmed	Three retinoid X receptor gene polymorphisms in plaque psoriasis and psoriasis guttata.	RXRA RXRB	2.46e-06	2	55	2	17341859
Pubmed	Cloning and tissue-specific expression of cDNAs for the human and mouse homologues of rat pancreatitis-associated protein (PAP).	REG3G REG3A	2.46e-06	2	55	2	7679928
Pubmed	Intestinal microbiota transplantation reveals the role of microbiota in dietary regulation of RegIIIβ and RegIIIγ expression in mouse intestine.	REG3G REG3A	2.46e-06	2	55	2	32560820
Pubmed	Retinoid X receptor ablation in adult mouse keratinocytes generates an atopic dermatitis triggered by thymic stromal lymphopoietin.	RXRA RXRB	2.46e-06	2	55	2	16199515
Pubmed	Oncogenic potential of truncated RXRα during colitis-associated colorectal tumorigenesis by promoting IL-6-STAT3 signaling.	TRAF6 RXRA	2.46e-06	2	55	2	30931933
Pubmed	Structural organization and chromosomal localization of a human gene (HIP/PAP) encoding a C-type lectin overexpressed in primary liver cancer.	REG3G REG3A	2.46e-06	2	55	2	8076648
Pubmed	A transcriptionally silent RXRalpha supports early embryonic morphogenesis and heart development.	RXRA RXRB	2.46e-06	2	55	2	19255444
Pubmed	The Reg3α (HIP/PAP) Lectin Suppresses Extracellular Oxidative Stress in a Murine Model of Acute Liver Failure.	REG3G REG3A	2.46e-06	2	55	2	25938566
Pubmed	Molecular cloning and tissue-specific expression of a new member of the regenerating protein family, islet neogenesis-associated protein-related protein.	REG3G REG3A	2.46e-06	2	55	2	10564727
Pubmed	Pancreatic islet-specific overexpression of Reg3β protein induced the expression of pro-islet genes and protected the mice against streptozotocin-induced diabetes mellitus.	REG3G REG3A	2.46e-06	2	55	2	21245462
Pubmed	Identification of endogenous retinoids, enzymes, binding proteins, and receptors during early postimplantation development in mouse: important role of retinal dehydrogenase type 2 in synthesis of all-trans-retinoic acid.	RXRA RXRB ADH4	5.64e-06	22	55	3	10753524
Pubmed	Divergent Hox Coding and Evasion of Retinoid Signaling Specifies Motor Neurons Innervating Digit Muscles.	HOXC8 REG3G REG3A	6.48e-06	23	55	3	28190640
Pubmed	Pancreatic STAT3 protects mice against caerulein-induced pancreatitis via PAP1 induction.	REG3G REG3A	7.36e-06	3	55	2	23064197
Pubmed	HNE Induces the Hyperexpression of MUC5AC in Chronic Rhinosinusitis With Nasal Polyps by Activating the TRAF6/Autophagy Regulatory Axis.	TRAF6 MUC5AC	7.36e-06	3	55	2	35915986
Pubmed	p8 improves pancreatic response to acute pancreatitis by enhancing the expression of the anti-inflammatory protein pancreatitis-associated protein I.	REG3G REG3A	7.36e-06	3	55	2	14660681
Pubmed	Unique response pathways are established by allosteric interactions among nuclear hormone receptors.	RXRA RXRB	7.36e-06	3	55	2	7758108
Pubmed	The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions.	RXRA RXRB	7.36e-06	3	55	2	9727070
Pubmed	Cooperative formation of high-order oligomers by retinoid X receptors: an unexpected mode of DNA recognition.	RXRA RXRB	7.36e-06	3	55	2	7831303
Pubmed	Second trimester amniotic fluid adiponectin level is affected by maternal tobacco exposure, insulin, and PAPP-A level.	ADIPOQ PAPPA	7.36e-06	3	55	2	22940118
Pubmed	Investigation of autism and GABA receptor subunit genes in multiple ethnic groups.	GABRA1 GABRA4	7.36e-06	3	55	2	16770606
Pubmed	Thymic stromal lymphopoietin overproduced by keratinocytes in mouse skin aggravates experimental asthma.	RXRA RXRB	7.36e-06	3	55	2	19188585
Pubmed	An unusual member of the nuclear hormone receptor superfamily responsible for X-linked adrenal hypoplasia congenita.	RXRA RXRB	7.36e-06	3	55	2	7990953
Pubmed	Vitamin-D receptor agonist calcitriol reduces calcification in vitro through selective upregulation of SLC20A2 but not SLC20A1 or XPR1.	RXRA RXRB	7.36e-06	3	55	2	27184385
Pubmed	Characterization of three RXR genes that mediate the action of 9-cis retinoic acid.	RXRA RXRB	7.36e-06	3	55	2	1312497
Pubmed	Multifunctional enhancers regulate mouse and human vitamin D receptor gene transcription.	RXRA RXRB	7.36e-06	3	55	2	19897601
Pubmed	Polymorphism of genes related to insulin sensitivity and the risk of biliary tract cancer and biliary stone: a population-based case-control study in Shanghai, China.	RXRA RXRB	7.36e-06	3	55	2	18375961
Pubmed	Detection of retinoid X receptors using specific monoclonal and polyclonal antibodies.	RXRA RXRB	7.36e-06	3	55	2	7980510
Pubmed	Home Dust Mites Promote MUC5AC Hyper-Expression by Modulating the sNASP/TRAF6 Axis in the Airway Epithelium.	TRAF6 MUC5AC	7.36e-06	3	55	2	36012669
Pubmed	Differential regulation of ligand-dependent and ligand-independent functions of the mouse retinoid X receptor beta by alternative splicing.	RXRA RXRB	7.36e-06	3	55	2	10049761
Pubmed	Immunohistochemical detection of the retinoid X receptors alpha, beta, and gamma in human prostate.	RXRA RXRB	7.36e-06	3	55	2	12514092
Pubmed	Genotype and Injury Effect on the Expression of a Novel Hypothalamic Protein Sushi Repeat-Containing Protein X-Linked 2 (SRPX2).	SRPX2 PLAU	7.36e-06	3	55	2	31362033
Pubmed	Crystal structure of the ligand-binding domain of the ultraspiracle protein USP, the ortholog of retinoid X receptors in insects.	RXRA RXRB	7.36e-06	3	55	2	11053444
Pubmed	Survival signal REG3α prevents crypt apoptosis to control acute gastrointestinal graft-versus-host disease.	REG3G REG3A	7.36e-06	3	55	2	30106382
Pubmed	Retinoid X receptors: X-ploring their (patho)physiological functions.	RXRA RXRB	7.36e-06	3	55	2	15608692
Pubmed	Chromosomal localization of the human retinoid X receptors.	RXRA RXRB	7.36e-06	3	55	2	8034312
Pubmed	HIP/PAP gene, encoding a C-type lectin overexpressed in primary liver cancer, is expressed in nervous system as well as in intestine and pancreas of the postimplantation mouse embryo.	REG3G REG3A	7.36e-06	3	55	2	10329612
Pubmed	Myocardial Accumulations of Reg3A, Reg3γ and Oncostatin M Are Associated with the Formation of Granulomata in Patients with Cardiac Sarcoidosis.	REG3G REG3A	7.36e-06	3	55	2	33923774
Pubmed	Differential 9-cis-retinoic acid-dependent transcriptional activation by murine retinoid X receptor alpha (RXR alpha) and RXR beta. Role of cell type and RXR domains.	RXRA RXRB	7.36e-06	3	55	2	8631847
Pubmed	Retinoid receptors trigger neuritogenesis in retinal degenerations.	RXRA RXRB	7.36e-06	3	55	2	21940995
Pubmed	The role of retinoid X receptor messenger RNA expression in curatively resected non-small cell lung cancer.	RXRA RXRB	7.36e-06	3	55	2	11839661
Pubmed	Extrasynaptic GABA(A) receptors couple presynaptic activity to postsynaptic inhibition in the somatosensory thalamus.	GABRA1 GABRA4	7.36e-06	3	55	2	24027285
Pubmed	Peroxisome proliferator-activated receptor gamma and retinoid X receptor transcription factors are released from activated human platelets and shed in microparticles.	RXRA RXRB	7.36e-06	3	55	2	18217139
Pubmed	Myocardial healing requires Reg3β-dependent accumulation of macrophages in the ischemic heart.	REG3G REG3A	7.36e-06	3	55	2	25751817
Pubmed	RXR gamma null mice are apparently normal and compound RXR alpha +/-/RXR beta -/-/RXR gamma -/- mutant mice are viable.	RXRA RXRB	7.36e-06	3	55	2	8799145
Pubmed	REG3A/REG3B promotes acinar to ductal metaplasia through binding to EXTL3 and activating the RAS-RAF-MEK-ERK signaling pathway.	REG3G REG3A	7.36e-06	3	55	2	34099862
Pubmed	IL-22-induced antimicrobial peptides are key determinants of mucosal vaccine-induced protection against H. pylori in mice.	REG3G REG3A	7.36e-06	3	55	2	27143303
Pubmed	Human TAF(II28) promotes transcriptional stimulation by activation function 2 of the retinoid X receptors.	RXRA RXRB	1.47e-05	4	55	2	8670810
Pubmed	Purification, cloning, and RXR identity of the HeLa cell factor with which RAR or TR heterodimerizes to bind target sequences efficiently.	RXRA RXRB	1.47e-05	4	55	2	1310259
Pubmed	Urokinase-induced migration of human vascular smooth muscle cells requires coupling of the small GTPases RhoA and Rac1 to the Tyk2/PI3-K signalling pathway.	TYK2 PLAU	1.47e-05	4	55	2	12719789
Pubmed	Retinoic acid biosynthetic activity and retinoid receptors in the olfactory mucosa of adult mice.	RXRA RXRB	1.47e-05	4	55	2	10079186
Pubmed	Synergistic activation of retinoic acid (RA)-responsive genes and induction of embryonal carcinoma cell differentiation by an RA receptor alpha (RAR alpha)-, RAR beta-, or RAR gamma-selective ligand in combination with a retinoid X receptor-specific ligand.	RXRA RXRB	1.47e-05	4	55	2	8524212
Pubmed	Transcriptional activation of Reg2 and Reg3β genes by glucocorticoids and interleukin-6 in pancreatic acinar and islet cells.	REG3G REG3A	1.47e-05	4	55	2	23147030
Pubmed	Intestinally secreted C-type lectin Reg3b attenuates salmonellosis but not listeriosis in mice.	REG3G REG3A	1.47e-05	4	55	2	22252863
Pubmed	Pregnane X Receptor Expression in Human Pancreatic Adenocarcinoma: Associations With Clinicopathologic Parameters, Tumor Proliferative Capacity, Patients' Survival, and Retinoid X Receptor Expression.	RXRA RXRB	1.47e-05	4	55	2	26355550
Pubmed	The antimicrobial protein REG3A regulates keratinocyte proliferation and differentiation after skin injury.	REG3G REG3A	1.47e-05	4	55	2	22727489
Pubmed	Retinoids activate RXR/CAR-mediated pathway and induce CYP3A.	RXRA RXRB	1.47e-05	4	55	2	19686701
Pubmed	Retinoid X receptors are essential for early mouse development and placentogenesis.	RXRA RXRB	1.47e-05	4	55	2	9892670
Pubmed	Coordinated age-dependent and pancreatic-specific expression of mouse Reg2Reg3α, and Reg3β genes.	REG3G REG3A	1.47e-05	4	55	2	21410322
Pubmed	Specific and redundant functions of retinoid X Receptor/Retinoic acid receptor heterodimers in differentiation, proliferation, and apoptosis of F9 embryonal carcinoma cells.	RXRA RXRB	1.47e-05	4	55	2	9348290
Pubmed	Retinoid X receptors orchestrate osteoclast differentiation and postnatal bone remodeling.	RXRA RXRB	1.47e-05	4	55	2	25574839
Pubmed	Physical interaction between retinoic acid receptor and Sp1: mechanism for induction of urokinase by retinoic acid.	PLAU RXRA	1.47e-05	4	55	2	10361124
Pubmed	Retinoic X receptor subtypes exert differential effects on the regulation of Trh transcription.	RXRA RXRB	1.47e-05	4	55	2	23896434
Pubmed	Overexpression of Reg3alpha increases cell growth and the levels of cyclin D1 and CDK4 in insulinoma cells.	REG3G REG3A	1.47e-05	4	55	2	19343564
Pubmed	The orphan nuclear receptor SHP inhibits hepatocyte nuclear factor 4 and retinoid X receptor transactivation: two mechanisms for repression.	RXRA RXRB	1.47e-05	4	55	2	10594021
Pubmed	Absence of thyroid hormone receptor beta-retinoid X receptor interactions in auditory function and in the pituitary-thyroid axis.	RXRA RXRB	1.47e-05	4	55	2	9804293
Pubmed	Sequence and characterization of a coactivator for the steroid hormone receptor superfamily.	RXRA RXRB	1.47e-05	4	55	2	7481822
Pubmed	IL17 Functions through the Novel REG3β-JAK2-STAT3 Inflammatory Pathway to Promote the Transition from Chronic Pancreatitis to Pancreatic Cancer.	REG3G REG3A	1.47e-05	4	55	2	26404002
Pubmed	Reg3β deficiency impairs pancreatic tumor growth by skewing macrophage polarization.	REG3G REG3A	1.47e-05	4	55	2	23867474
Pubmed	Mucin Muc2 deficiency and weaning influences the expression of the innate defense genes Reg3β, Reg3γ and angiogenin-4.	REG3G REG3A	1.47e-05	4	55	2	22723890
Pubmed	RXRs control serous macrophage neonatal expansion and identity and contribute to ovarian cancer progression.	RXRA RXRB	1.47e-05	4	55	2	32246014
Pubmed	The retinoid receptors.	RXRA RXRB	1.47e-05	4	55	2	7967725
Pubmed	The gut peptide Reg3g links the small intestine microbiome to the regulation of energy balance, glucose levels, and gut function.	REG3G REG3A	1.47e-05	4	55	2	36240758
Pubmed	Association of protein kinase C with GABA(A) receptors containing alpha1 and alpha4 subunits in the cerebral cortex: selective effects of chronic ethanol consumption.	GABRA1 GABRA4	1.47e-05	4	55	2	12091471
Pubmed	Retina-specific nuclear receptor: A potential regulator of cellular retinaldehyde-binding protein expressed in retinal pigment epithelium and Müller glial cells.	RXRA RXRB	1.47e-05	4	55	2	10611353
Pubmed	Effects of retinoid ligands on RIP140: molecular interaction with retinoid receptors and biological activity.	RXRA RXRB	1.47e-05	4	55	2	12549917
Pubmed	The pancreas responds to remote damage and systemic stress by secretion of the pancreatic secretory proteins PSP/regI and PAP/regIII.	REG3G REG3A	1.47e-05	4	55	2	28415799
Pubmed	Identification of a novel Reg family gene, Reg IIIdelta, and mapping of all three types of Reg family gene in a 75 kilobase mouse genomic region.	REG3G REG3A	1.47e-05	4	55	2	10767532
Pubmed	Ontogeny of rdh9 (Crad3) expression: ablation causes changes in retinoid and steroid metabolizing enzymes, but RXR and androgen signaling seem normal.	RXRA RXRB ADH4	1.80e-05	32	55	3	17270348
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	SNED1 SRPX2 PAPPA	2.50e-04	57	39	3	1179
GeneFamily	Gamma-aminobutyric acid type A receptor subunits	GABRA1 GABRA4	7.58e-04	19	39	2	563
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	REG3G REG3A	3.53e-03	41	39	2	1298
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF827 KLF9 ZNF184 ZNF76 IKZF1 ZNF512	4.09e-03	718	39	6	28
GeneFamily	Nuclear hormone receptors	RXRA RXRB	5.00e-03	49	39	2	71
Coexpression	NABA_MATRISOME	SNED1 EYS SRPX2 ADIPOQ CELA2A REG3G REG3A PAPPA PLAU HCFC2 MUC5AC FBN3 HAPLN1	1.48e-07	1026	55	13	M5889
Coexpression	GSE26343_UNSTIM_VS_LPS_STIM_NFAT5_KO_MACROPHAGE_UP	TRAF6 ZNF827 KLF9 SUPV3L1 B3GALNT2 PLAU	3.67e-06	198	55	6	M8649
Coexpression	NABA_MATRISOME	SNED1 SRPX2 ADIPOQ CELA2A REG3G REG3A PAPPA PLAU HCFC2 MUC5AC HAPLN1	6.53e-06	1008	55	11	MM17056
Coexpression	URS_ADIPOCYTE_DIFFERENTIATION_UP	ADIPOQ MAP4K3 RXRA RXRB	1.14e-05	66	55	4	M15476
Coexpression	NABA_CORE_MATRISOME	SNED1 EYS SRPX2 ADIPOQ FBN3 HAPLN1	2.38e-05	275	55	6	M5884
Coexpression	YAO_HOXA10_TARGETS_VIA_PROGESTERONE_UP	ADIPOQ KLF9 REG3G REG3A	4.05e-05	91	55	4	MM622
Coexpression	NABA_ECM_GLYCOPROTEINS	SNED1 EYS SRPX2 ADIPOQ FBN3	5.71e-05	196	55	5	M3008
Coexpression	GSE41176_WT_VS_TAK1_KO_UNSTIM_BCELL_DN	HOXC8 CELA2A MACROD2 MARF1 ADH4	6.13e-05	199	55	5	M9941
Coexpression	KONDO_EZH2_TARGETS	HOXC8 MAP4K3 KLF9 DNER ZNF76	1.19e-04	229	55	5	M5301
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX15 HOXC8 ADIPOQ CELA2A REG3G REG3A	8.13e-08	176	55	6	60740f676db5d259ef3046bd5bc7b7b14924ecee
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EYS ROR1 DNER PAPPA GNAL HAPLN1	1.28e-07	190	55	6	3f22c118d552345f731d4d49f0bcb5765d93de3b
ToppCell	Fibroblasts-CD34+_Fibroblasts\|Fibroblasts / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	FAM184A RPL37 DLX5 GNAL HAPLN1 ADH4	1.49e-07	195	55	6	c6b5249ac8714b1b701cde31d00ab53f28355c36
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SNED1 BCO2 MAP4K3 PLAU RXRA HAPLN1	1.63e-07	198	55	6	09be07ebfc3e49c3858e9b74605b69cf4fc28b56
ToppCell	Hippocampus-Neuronal-Inhibitory\|Hippocampus / BrainAtlas - Mouse McCarroll V32	FSTL5 DNER DLX5 GNAL HAPLN1	3.03e-06	182	55	5	b54ae650c04dfd0759c5f5e752b9bf684dd36516
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ROR1 DNER DLX5 GNAL HAPLN1	3.37e-06	186	55	5	948815663c212c4311329d503b5991cbbbff9808
ToppCell	343B-Fibroblasts-Fibroblast-E-\|343B / Donor, Lineage, Cell class and subclass (all cells)	SOX15 SRPX2 PAPPA GNAL ST3GAL3	3.37e-06	186	55	5	1bac7825c2fe3e6cdff65026b09b9ccaa40fa27f
ToppCell	343B-Fibroblasts-Fibroblast-E\|343B / Donor, Lineage, Cell class and subclass (all cells)	SOX15 SRPX2 PAPPA GNAL ST3GAL3	3.37e-06	186	55	5	59db239f1864a5d4f1570c93219dbd7ac5b6db35
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EYS ROR1 DNER GNAL HAPLN1	3.55e-06	188	55	5	8de5a07301f9b5984680c873e5a92395b5ed3dd3
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EYS ROR1 PAPPA GNAL HAPLN1	3.73e-06	190	55	5	e58e4b6fbeb4368f738adac67ec10879c0966f0f
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FSTL5 DNER DLX5 GNAL HAPLN1	3.93e-06	192	55	5	bf1943715085c4124b1675888b0615c9500ec888
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EYS ROR1 DNER GNAL HAPLN1	4.03e-06	193	55	5	c4b22b62f3cc7bf0ec0eba76e1504c236290bbc9
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FSTL5 DNER DLX5 GNAL HAPLN1	4.13e-06	194	55	5	52aebb0b563e2c2058e7f0554ae870e47692b163
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FSTL5 DNER DLX5 GNAL HAPLN1	4.13e-06	194	55	5	bd06e2b8d8c06cddf2e4f58849b86e09013acae1
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)\|Neuronal / cells hierarchy compared to all cells using T-Statistic	EYS ROR1 DNER PAPPA GNAL	4.79e-06	200	55	5	1276bfa911fddada4235e12e3081baa53164574b
ToppCell	mild_COVID-19_(asymptomatic)-NK_CD56bright\|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)	TMEM182 ZNF827 B3GALNT2 DNAH6	3.64e-05	151	55	4	2470162f4b56bc505db166a6eb0fa54847759df8
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AFMID LIMD2 TRAF6 IKZF1	3.64e-05	151	55	4	75c068b3e3aae5f9ba64d5fa5d1e2105a60e4293
ToppCell	Posterior_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	FSTL5 DNER DLX5 HAPLN1	4.03e-05	155	55	4	105d59d8a1bb8cb37eef2c1767d737b2108ac7c5
ToppCell	5'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HOXC8 MAP4K3 HCFC2 AP4B1	4.13e-05	156	55	4	d411116d54add2d4fe649a97ac54cb94c085312f
ToppCell	Frontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	DNER DLX5 RXRA HAPLN1	4.45e-05	159	55	4	7f29f9dcf25ffa1822b137c571e9ac16defc6292
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SNED1 FAM184A MACROD2 DNAH6	4.79e-05	162	55	4	373513f9d0e5007b2e10a8b78d4909dcce9e3b62
ToppCell	Posterior_cortex-Neuronal-Inhibitory\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	FSTL5 DNER DLX5 HAPLN1	5.39e-05	167	55	4	9a84f45345c75f2c8ff38a04245aadee2a26a240
ToppCell	TCGA-Pancreas\|World / Sample_Type by Project: Shred V9	CELA2A REG3G REG3A MUC5AC	5.51e-05	168	55	4	279d5fcf9bd3f56ab560e37eed6fb3bd57dd93de
ToppCell	Hippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	FSTL5 DNER DLX5 HAPLN1	5.64e-05	169	55	4	c135d7ae0490d0024e0f4bd8c4ad42f6674a61da
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SNED1 BCO2 LMLN DNAH6	5.64e-05	169	55	4	fba841664939c771881ba97f14ef1df6635c04ff
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-2_VIP_RPL41P3\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HOXC8 DLX5 FBN3 HAPLN1	5.77e-05	170	55	4	31e3f57673c99f4d8ef30faa9c40e5f7f5bf6460
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_low-phase\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LMLN IKZF1 GNAL AP4B1	6.18e-05	173	55	4	506efcaa5afd6ed5e565c4c4def6a4505fea97c5
ToppCell	10x5'-Liver-Lymphocytic_T_CD8-Tnaive/CM_CD8\|Liver / Manually curated celltypes from each tissue	FAM184A EYS RPL37 REG3A	6.32e-05	174	55	4	03918ca51ae3b4c9c1a74769b08ea23f518286ba
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL37 CELA2A REG3G REG3A	6.60e-05	176	55	4	12bccbd56742fcfe19749da802ea1cf62ec9a872
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL37 CELA2A REG3G REG3A	6.90e-05	178	55	4	415a02ad14df9deba988990118b00fb84ee524a8
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DNER DLX5 GNAL FBN3	6.90e-05	178	55	4	3c973aac16988e88f5677d3d695dd772ccfd6570
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FSTL5 DNER GNAL HAPLN1	7.05e-05	179	55	4	c7afbd10072d36a35cd20ae73670d76b9cefd22d
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ROR1 DNER GNAL HAPLN1	7.36e-05	181	55	4	bd7e9437839bca543ca5945df43d6525e6a312a8
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL37 CELA2A REG3G REG3A	7.36e-05	181	55	4	cf8f7798559fedf91ee21b3ebc93171cfd14f89f
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FSTL5 DNER DLX5 HAPLN1	7.52e-05	182	55	4	7dc61e901428cea04f00ebb0939a44d21a6145c6
ToppCell	droplet-Pancreas-PANCREAS\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL37 CELA2A REG3G REG3A	7.52e-05	182	55	4	ecb8c1d0b9e0766fae4dd2568456eb78a3cfce9a
ToppCell	droplet-Pancreas-PANCREAS-30m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL37 CELA2A REG3G REG3A	7.52e-05	182	55	4	cf1ccfc4709364763fa73e60d5f2c05ce268d5c1
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SNED1 FAM184A MACROD2 DNAH6	7.52e-05	182	55	4	a8cc56f32efe180e8fb5d69dbe606a794b3db700
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FSTL5 DNER GNAL FBN3	7.52e-05	182	55	4	420a8fd30543e37a66ba0786215d056d308660d0
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SOX15 SRPX2 DNER PAPPA	7.52e-05	182	55	4	3dfa9187e9d2bab1d199079d29209c4648220ada
ToppCell	5'-GW_trimst-2-LargeIntestine-Hematopoietic-T_cells\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LIMD2 EYS IKZF1 ARAP2	7.52e-05	182	55	4	09d0793245d3d77ab5fc384c0b62637f736da50b
ToppCell	10x3'2.3-week_17-19-Mesenchymal_osteo-stroma-early_osteoblast\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	SRPX2 PAPPA DLX5 HAPLN1	7.68e-05	183	55	4	27a57cd8ea924420e182f3d72f5b29b00dea8fa0
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EYS ROR1 PAPPA HAPLN1	7.68e-05	183	55	4	04d3cc76038b8192c915f1c08c3e26f2ad3b3779
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TMEM182 FSTL5 DNER HAPLN1	7.68e-05	183	55	4	e3ffef2b57dc5b96466dccc9cd54ba326ccf378a
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EYS DNER GNAL HAPLN1	7.85e-05	184	55	4	2ba98708dfd7f1b2a661578a334684094ff453ad
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FSTL5 DNER GNAL HAPLN1	8.01e-05	185	55	4	16e9ccea0e3b95d90dc48ef74206c805681dac0b
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	FSTL5 DNER DLX5 HAPLN1	8.01e-05	185	55	4	739260f8abebaf10a5cc49d91726278579e26170
ToppCell	droplet-Kidney-nan-18m-Epithelial-Epcam____podocyte-3\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX15 CELA2A REG3G DNAH6	8.18e-05	186	55	4	29c79b5a29907d4f3f87ad2ca04840c0f15b7d4e
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FSTL5 ROR1 DNER HAPLN1	8.18e-05	186	55	4	77592a6397b44b2b59a4fc39d7224dd95343efe6
ToppCell	facs-Brain_Myeloid-Hippocampus_-18m-Myeloid\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LIMD2 RPL37 CELA2A MARF1	8.18e-05	186	55	4	28699e3574d3a183190bdb6c5db2219167d41579
ToppCell	facs-Brain_Myeloid-Hippocampus_-18m-Myeloid-nan\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LIMD2 RPL37 CELA2A MARF1	8.18e-05	186	55	4	f3345fad9559ec222062a6f516b9d3f815d98acf
ToppCell	facs-Brain_Myeloid-Hippocampus_-18m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LIMD2 RPL37 CELA2A MARF1	8.18e-05	186	55	4	77baa0075e53ccb654a561e3289eba41deab8561
ToppCell	facs-Brain_Myeloid-Hippocampus_\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LIMD2 RPL37 CELA2A MARF1	8.18e-05	186	55	4	eb1d1941cd6e4d9f0655aff3ba8df3c29c06b3a2
ToppCell	facs-Brain_Myeloid-Hippocampus_-18m\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LIMD2 RPL37 CELA2A MARF1	8.18e-05	186	55	4	06e6e805f90d92c870f36b79fa0749988a4595bb
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FAM184A MACROD2 DNER PLAU	8.35e-05	187	55	4	77886f99c229610abd28c4c370d2c7d1536c9782
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ROR1 MACROD2 FBN3 ARAP2	8.52e-05	188	55	4	eea652bab161f19148a883e7e3fe2523b36b3cea
ToppCell	15-Distal-Epithelial-Secretory_progenitor\|Distal / Age, Tissue, Lineage and Cell class	FSTL5 MUC5AC ARAP2 SPINK5	8.52e-05	188	55	4	9a64fb07de611de38d6f24673feb3b81a5e85384
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FSTL5 ROR1 DNER HAPLN1	8.52e-05	188	55	4	3139540a656c0436b2123ea50741ff8d00112165
ToppCell	facs-Kidney-nan-3m-Mesenchymal-mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SNED1 SRPX2 HOXC8 GABRA4	8.70e-05	189	55	4	a5306561026e4dfcc39beeb785e5108ac595d136
ToppCell	facs-Kidney-nan-3m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SNED1 SRPX2 HOXC8 GABRA4	8.70e-05	189	55	4	381058f55908f84375b54601d617389ef43ab855
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FSTL5 MACROD2 ARAP2 GABRA1	8.70e-05	189	55	4	7659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-4_LAMP5_DUSP4_(Lamp5_Rosehip)\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FSTL5 DNER DLX5 HAPLN1	8.70e-05	189	55	4	979b7fa947538aa7ca4a219263da2575869a2caa
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DNER DLX5 GNAL HAPLN1	8.70e-05	189	55	4	78cf414b98bcb19deb934409acddaad1cd51b67f
ToppCell	facs-Kidney-nan-3m-Mesenchymal-mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SNED1 SRPX2 HOXC8 GABRA4	8.70e-05	189	55	4	302b950a6ad578f8aeff7ea6fd15fe631225287d
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FAM184A ROR1 MACROD2 FBN3	8.88e-05	190	55	4	8aea807a2bcf0b653b4de6202b6ecb0f0683cc2e
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EYS ROR1 PAPPA GNAL	8.88e-05	190	55	4	305fbef734c350cfbf786ca7ff6e07093aab56ea
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EYS PAPPA GNAL HAPLN1	8.88e-05	190	55	4	39ab890104b4264c68a968f920f4ccd84f0bc681
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FSTL5 MACROD2 ARAP2 GABRA1	9.06e-05	191	55	4	60ff989fe99d243a3d52955223680cdd1f1917a4
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FAM184A ROR1 MACROD2 FBN3	9.06e-05	191	55	4	ca5669bd6f4a17471acae3eb229f845cc2e08efa
ToppCell	Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|World / Lineage, Cell type, age group and donor	FAM184A ROR1 MACROD2 FBN3	9.06e-05	191	55	4	d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FSTL5 DNER DLX5 HAPLN1	9.06e-05	191	55	4	fa50a3c7ff86e1ee07100da1ace0b0fa1b0ab26b
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_chondroblast_(18)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	RPL37 MACROD2 PAPPA HAPLN1	9.25e-05	192	55	4	d0649410cf5eacdb0c1dce70e37c7473ef5fddfa
ToppCell	PCW_05-06-Epithelial-Epithelial_airway-epi_proximal_progenitor2_(4)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	FSTL5 ARAP2 GABRA1 SPINK5	9.25e-05	192	55	4	c15841f35e24d6ef6ce2a9a6dc62e66efdc3d9d5
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DNER DLX5 GNAL HAPLN1	9.25e-05	192	55	4	67d6230e32d446dcb12047fae2c3f1faa80dd720
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EYS ROR1 DNER PAPPA	9.43e-05	193	55	4	4979862c0c16e6b4baa4c79894f1d237c861f5a5
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DNER DLX5 GNAL HAPLN1	9.43e-05	193	55	4	9f9eb241b0b82a6f12de6921c3acf6fed7cf65bb
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EYS ROR1 DNER PAPPA	9.43e-05	193	55	4	e74fdc8718fe0933e1f4dd3fe37e2134983b99b6
ToppCell	droplet-Tongue-nan-3m-Epithelial-basal_cell\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX15 RPL37 KLF9 PAPPA	9.62e-05	194	55	4	1eef012e53e43c4f4f6968baac3cc28727c4a9b5
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EYS ROR1 DNER PAPPA	9.62e-05	194	55	4	e5990880961d2469759ce4b3b20ae93ace3ebd1f
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FSTL5 DNER DLX5 HAPLN1	9.62e-05	194	55	4	02a9cc821c2b14aa7d0e55661a5fab66364474e1
ToppCell	COVID-19-Heart-CM_1\|Heart / Disease (COVID-19 only), tissue and cell type	TMEM182 BCO2 ROR1 MACROD2	9.82e-05	195	55	4	f1ef50331eda8f1239dba6ea970df4eaccf032f1
ToppCell	droplet-Tongue-nan-3m-Epithelial-basal_cell_of_epidermis\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX15 RPL37 KLF9 PAPPA	9.82e-05	195	55	4	a31a8c0e8e666acfc6737fa2c54ebd6f35605520
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SNED1 PLAU RXRA HAPLN1	1.00e-04	196	55	4	85507488f83d8f71b3ee2ad5e5aa0b6ad6193873
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FSTL5 DNER DLX5 HAPLN1	1.00e-04	196	55	4	7af6c5147ac859353504d19727dbe24f63a29dd4
ToppCell	Mild/Remission\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	LIMD2 RPL37 MACROD2 MARF1	1.00e-04	196	55	4	71603a3b7df40eb3f267345f55e44a812fea7926
ToppCell	10x5'v1-week_12-13-Mesenchymal_osteo-stroma-early_osteoblast\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	SRPX2 PAPPA DLX5 HAPLN1	1.02e-04	197	55	4	2ca5ebb708935a90b12b8e98a22ae2d664ed002e
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Deep_Layer\|World / Primary Cells by Cluster	FSTL5 DNER GABRA1 SPINK5	1.02e-04	197	55	4	41e823b14697827f657b13adb3afa581bd91a9cb
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SRPX2 DNER PAPPA PLAU	1.02e-04	197	55	4	ab5d3ebc73bd7cfc64381d14b92878b370205186
ToppCell	5'-Adult-Appendix-Mesenchymal\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SRPX2 DNER PAPPA PLAU	1.02e-04	197	55	4	b11a5d909942a4299cbc0b27332b1a3f66f3bccd
ToppCell	Bronchial-10x5prime-Stromal-Mesofibroblastic-Mesothelia\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ROR1 REG3G PAPPA GABRA1	1.02e-04	197	55	4	26888af95a7cc082a1f1218af35b1f07cb9436ed
ToppCell	Bronchial-10x5prime-Stromal-Mesofibroblastic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ROR1 REG3G PAPPA GABRA1	1.02e-04	197	55	4	438de7f0d35d81d5f5e41dcef7b2c54b6da03df4
ToppCell	Caecum-T_cell-Tcm\|T_cell / Region, Cell class and subclass	LIMD2 FAM184A RPL37 IKZF1	1.04e-04	198	55	4	f889ee80c641540fd8db9eaefcd16aa51ddb2c01
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Layer_IV-2\|World / Primary Cells by Cluster	FSTL5 MACROD2 GNAL GABRA4	1.06e-04	199	55	4	f09b40245d3d826275bbe5f508dedccc75a911bd
ToppCell	Mild/Remission-B_naive-9\|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)	LIMD2 INTS6 RPL37 MACROD2	1.06e-04	199	55	4	e9af3c6a05f435ac8d7066f54feb653012b51ffb
ToppCell	Caecum-(1)_T_cell-(14)_Tcm\|Caecum / shred on region, Cell_type, and subtype	LIMD2 FAM184A RPL37 IKZF1	1.06e-04	199	55	4	0f89426e8dec0cbe78f6c55caaa196daf0eaf66a
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Layer_IV\|World / Primary Cells by Cluster	FSTL5 MACROD2 GNAL GABRA4	1.06e-04	199	55	4	e45448ec4db8875c8aaa9aad109a10e2905a4226
ToppCell	Caecum-T_cell-Tcm\|Caecum / Region, Cell class and subclass	LIMD2 FAM184A RPL37 IKZF1	1.06e-04	199	55	4	cab97db995a7d7df3b8f0511139ef0fe65ee55b9
ToppCell	Tracheal-10x3prime_v2-Stromal-Fibroblastic-Fibro_peribronchial\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	ROR1 PAPPA DLX5 HAPLN1	1.06e-04	199	55	4	e9009eee7f77b9c9917f8e0e723001d9e76eb553
ToppCell	Mild/Remission-B_naive-9\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	LIMD2 INTS6 RPL37 MACROD2	1.06e-04	199	55	4	0451b1536be3725a520bfdd2b3dff133bea812e8
ToppCell	Neuronal-Inhibitory-iA-iA_2(LAMP5)-LCP2--L1-4\|Neuronal / cells hierarchy compared to all cells using T-Statistic	FSTL5 MACROD2 DNER HAPLN1	1.08e-04	200	55	4	f268cb1bb047e88913a828614b0a77871f5f8814
Computational	Genes in the cancer module 484.	TYK2 LIMD2 RPL37	2.31e-04	42	31	3	MODULE_484
Drug	Phthalylsulfathiazole [85-73-4]; Up 200; 10uM; PC3; HT_HG-U133A	LIMD2 SNED1 PDE12 PAPPA IKZF1 GNAL	7.92e-06	197	55	6	4653_UP
Drug	Deptropine citrate [2169-75-7]; Up 200; 7.6uM; MCF7; HT_HG-U133A	ADIPOQ ROR1 ZNF76 PLAU MUC5AC SPINK5	8.39e-06	199	55	6	5543_UP
Drug	phenazepam	AFMID GABRA1 GABRA4	1.06e-05	18	55	3	CID000040113
Drug	Bexarotene	RXRA RXRB	1.72e-05	3	55	2	DB00307
Drug	2-hydroxyphytanic acid	RXRA RXRB	1.72e-05	3	55	2	ctd:C002585
Drug	AC1O5SBP	RXRA RXRB	1.72e-05	3	55	2	CID006439746
Drug	nonylamine	AFMID DNER	1.72e-05	3	55	2	CID000016214
Drug	beta-CCE	AFMID GABRA1 GABRA4	2.95e-05	25	55	3	CID000105078
Drug	AGN 190727	RXRA RXRB	3.43e-05	4	55	2	CID006439768
Drug	7-methoxycitronellal	RXRA RXRB	5.70e-05	5	55	2	CID000019223
Drug	7-methoxycitronellic acid	RXRA RXRB	5.70e-05	5	55	2	CID000171516
Drug	13,14-dihydroretinol	RXRA RXRB	5.70e-05	5	55	2	CID000446798
Drug	Lorazepam	GABRA1 GABRA4	5.70e-05	5	55	2	ctd:D008140
Drug	T0070907	ADIPOQ RXRA RXRB	5.72e-05	31	55	3	CID002777391
Drug	CD367	INTS6 RXRA RXRB	6.91e-05	33	55	3	CID000119342
Drug	Alitretinoin	RXRA RXRB	8.54e-05	6	55	2	DB00523
Drug	Meprobamate	GABRA1 GABRA4	8.54e-05	6	55	2	DB00371
Drug	Adapalene	RXRA RXRB	8.54e-05	6	55	2	DB00210
Drug	triphenyltin hydroxide	RXRA RXRB	8.54e-05	6	55	2	ctd:C007567
Drug	Methoprene	RXRA RXRB	8.54e-05	6	55	2	ctd:D008726
Drug	Etretinate	RXRA RXRB	8.54e-05	6	55	2	DB00926
Drug	zaleplon	GABRA1 GABRA4	8.54e-05	6	55	2	ctd:C085665
Drug	Ro 41-5253	MUC5AC RXRA RXRB	9.78e-05	37	55	3	CID005312120
Drug	Butylparaben [94-26-8]; Up 200; 20.6uM; PC3; HT_HG-U133A	SNED1 PDE12 IKZF1 DLX5 SPINK5	1.08e-04	195	55	5	4647_UP
Drug	3-Acetylcoumarin [3949-36-8]; Up 200; 21.2uM; PC3; HT_HG-U133A	SNED1 PDE12 IKZF1 GNAL SPINK5	1.10e-04	196	55	5	4664_UP
Drug	Diloxanide furoate [3736-81-0]; Up 200; 12.2uM; HL60; HT_HG-U133A	SNED1 ROR1 GNAL GABRA1 SPINK5	1.13e-04	197	55	5	3062_UP
Drug	Rapamycin; Down 200; 0.1uM; HL60; HT_HG-U133A	LIMD2 SNED1 ZNF76 IKZF1 ARAP2	1.13e-04	197	55	5	2702_DN
Drug	Troleandomycin [2751-09-9]; Up 200; 5uM; MCF7; HT_HG-U133A	FAM184A PDE12 ZNF76 IKZF1 SPINK5	1.16e-04	198	55	5	1465_UP
Drug	Acitretin	RXRA RXRB	1.19e-04	7	55	2	DB00459
Drug	AGN 191659	RXRA RXRB	1.19e-04	7	55	2	CID006366726
Drug	AGN 190121	RXRA RXRB	1.19e-04	7	55	2	CID006441236
Drug	Vitamin A	BCO2 MUC5AC RXRA RXRB ADH4	1.21e-04	200	55	5	ctd:D014801
Drug	pyrazolanthrone	ADIPOQ REG3G PAPPA PLAU MUC5AC RXRA	1.24e-04	322	55	6	ctd:C432165
Drug	E-guggulsterone	ADIPOQ PLAU RXRA RXRB	1.36e-04	108	55	4	CID006439929
Drug	HX 600	RXRA RXRB	1.59e-04	8	55	2	ctd:C104181
Drug	oxathiane	AFMID DNER	1.59e-04	8	55	2	CID000027596
Drug	rutamarin	ADIPOQ RXRA	1.59e-04	8	55	2	ctd:C022850
Drug	Flumazenil	GABRA1 GABRA4	1.59e-04	8	55	2	ctd:D005442
Drug	TTNN	RXRA RXRB	1.59e-04	8	55	2	CID000135754
Drug	AC1O5JP6	RXRA RXRB	1.59e-04	8	55	2	CID006435379
Drug	CGP 36742	LMLN GABRA1 GABRA4	1.65e-04	44	55	3	CID000130021
Drug	Ethchlorvynol	GABRA1 GABRA4	2.04e-04	9	55	2	DB00189
Drug	Steroids	PAPPA GABRA1	2.04e-04	9	55	2	ctd:D013256
Drug	CNQX	INTS6 GABRA1 HAPLN1 GABRA4	2.45e-04	126	55	4	CID000002821
Drug	Secobarbital	GABRA1 GABRA4	2.55e-04	10	55	2	DB00418
Drug	Chlordiazepoxide	GABRA1 GABRA4	2.55e-04	10	55	2	DB00475
Drug	Metharbital	GABRA1 GABRA4	2.55e-04	10	55	2	DB00463
Drug	Pentobarbital	GABRA1 GABRA4	2.55e-04	10	55	2	DB00312
Drug	Talbutal	GABRA1 GABRA4	2.55e-04	10	55	2	DB00306
Drug	Clobazam	GABRA1 GABRA4	2.55e-04	10	55	2	DB00349
Drug	Butalbital	GABRA1 GABRA4	2.55e-04	10	55	2	DB00241
Drug	Butabarbital	GABRA1 GABRA4	2.55e-04	10	55	2	DB00237
Drug	Bromazepam	GABRA1 GABRA4	2.55e-04	10	55	2	DB01558
Drug	Barbituric acid derivative	GABRA1 GABRA4	2.55e-04	10	55	2	DB01496
Drug	Barbital	GABRA1 GABRA4	2.55e-04	10	55	2	DB01483
Drug	HX 630	RXRA RXRB	2.55e-04	10	55	2	ctd:C422175
Drug	Hexobarbital	GABRA1 GABRA4	2.55e-04	10	55	2	DB01355
Drug	Aprobarbital	GABRA1 GABRA4	2.55e-04	10	55	2	DB01352
Drug	Amobarbital	GABRA1 GABRA4	2.55e-04	10	55	2	DB01351
Drug	Heptabarbital	GABRA1 GABRA4	2.55e-04	10	55	2	DB01354
Drug	Butethal	GABRA1 GABRA4	2.55e-04	10	55	2	DB01353
Drug	Clonazepam	GABRA1 GABRA4	2.55e-04	10	55	2	DB01068
Drug	AC1L1FKW	GABRA1 GABRA4	2.55e-04	10	55	2	CID000003281
Drug	Methylphenobarbital	GABRA1 GABRA4	2.55e-04	10	55	2	DB00849
Drug	Oxazepam	GABRA1 GABRA4	2.55e-04	10	55	2	DB00842
Drug	Primidone	GABRA1 GABRA4	2.55e-04	10	55	2	DB00794
Drug	diazepinylbenzoic acid	RXRA RXRB	2.55e-04	10	55	2	ctd:C438269
Drug	Midazolam	GABRA1 GABRA4	2.55e-04	10	55	2	DB00683
Drug	Flurazepam	GABRA1 GABRA4	2.55e-04	10	55	2	DB00690
Drug	flumazenil	AFMID GABRA1 GABRA4	3.03e-04	54	55	3	CID000003373
Drug	Thiopental	GABRA1 GABRA4	3.11e-04	11	55	2	DB00599
Drug	Alprazolam	GABRA1 GABRA4	3.11e-04	11	55	2	DB00404
Drug	fosazepam	GABRA1 GABRA4	3.11e-04	11	55	2	CID000037114
Drug	AGN 191701	RXRA RXRB	3.11e-04	11	55	2	CID006438168
Drug	C19H18ClN3O	GABRA1 GABRA4	3.11e-04	11	55	2	CID000027452
Drug	flutoprazepam	GABRA1 GABRA4	3.11e-04	11	55	2	CID000003400
Drug	Arfendazam	GABRA1 GABRA4	3.11e-04	11	55	2	CID000065803
Drug	Temazepam	GABRA1 GABRA4	3.11e-04	11	55	2	DB00231
Drug	Nitrazepam	GABRA1 GABRA4	3.11e-04	11	55	2	DB01595
Drug	Lorazepam	GABRA1 GABRA4	3.11e-04	11	55	2	DB00186
Drug	UVI 3003	RXRA RXRB	3.11e-04	11	55	2	ctd:C525131
Drug	Musk T	RXRA RXRB	3.11e-04	11	55	2	CID000061014
Drug	camazepam	GABRA1 GABRA4	3.11e-04	11	55	2	CID000037367
Drug	Phenobarbital	GABRA1 GABRA4	3.11e-04	11	55	2	DB01174
Drug	triflubazam	GABRA1 GABRA4	3.11e-04	11	55	2	CID000031157
Drug	Bu-1014	GABRA1 GABRA4	3.11e-04	11	55	2	CID015942721
Drug	Zapizolam	GABRA1 GABRA4	3.11e-04	11	55	2	CID000068832
Drug	Reclazepam	GABRA1 GABRA4	3.11e-04	11	55	2	CID003052777
Drug	iclazepam	GABRA1 GABRA4	3.11e-04	11	55	2	CID000068777
Drug	menitrazepam	GABRA1 GABRA4	3.11e-04	11	55	2	CID000189875
Drug	Triazolam	GABRA1 GABRA4	3.11e-04	11	55	2	DB00897
Drug	Serin hydrazid	GABRA1 GABRA4	3.11e-04	11	55	2	CID000041637
Drug	sulazepam	GABRA1 GABRA4	3.11e-04	11	55	2	CID000017931
Drug	elfazepam	GABRA1 GABRA4	3.11e-04	11	55	2	CID000065445
Drug	Clorazepate	GABRA1 GABRA4	3.11e-04	11	55	2	DB00628
Drug	uldazepam	GABRA1 GABRA4	3.11e-04	11	55	2	CID000034274
Drug	gidazepam	GABRA1 GABRA4	3.11e-04	11	55	2	CID000121919
Drug	fletazepam	GABRA1 GABRA4	3.11e-04	11	55	2	CID000036834
Drug	SB-205384	GABRA1 GABRA4	3.72e-04	12	55	2	CID000197690
Drug	U-93631	GABRA1 GABRA4	3.72e-04	12	55	2	CID000197626
Disease	Myocardial Preinfarction Syndrome	PAPPA PLAU	1.02e-05	3	55	2	C0086666
Disease	Angina, Unstable	PAPPA PLAU	1.02e-05	3	55	2	C0002965
Disease	chronic obstructive pulmonary disease (implicated_via_orthology)	PLAU MUC5AC	1.02e-05	3	55	2	DOID:3083 (implicated_via_orthology)
Disease	acute pancreatitis (implicated_via_orthology)	REG3G REG3A	3.40e-05	5	55	2	DOID:2913 (implicated_via_orthology)
Disease	pneumonia (implicated_via_orthology)	REG3G REG3A	1.52e-04	10	55	2	DOID:552 (implicated_via_orthology)
Disease	Rheumatoid Arthritis	TYK2 TRAF6 ADIPOQ HAPLN1	3.15e-04	174	55	4	C0003873
Disease	amyotrophic lateral sclerosis, age at onset	ST3GAL3 ARAP2	3.53e-04	15	55	2	EFO_0004847, MONDO_0004976
Disease	alcohol dependence	FSTL5 GNAL MUC5AC ADH4	3.81e-04	183	55	4	MONDO_0007079
Disease	Tremor, Rubral	GABRA1 GABRA4	4.03e-04	16	55	2	C0750940
Disease	Ataxia, Appendicular	GABRA1 GABRA4	4.03e-04	16	55	2	C0750937
Disease	Ataxia, Motor	GABRA1 GABRA4	4.03e-04	16	55	2	C0278161
Disease	Abnormal coordination	GABRA1 GABRA4	4.03e-04	16	55	2	C0520966
Disease	Ataxia, Truncal	GABRA1 GABRA4	4.03e-04	16	55	2	C0427190
Disease	Ataxia, Sensory	GABRA1 GABRA4	4.03e-04	16	55	2	C0240991
Disease	Metabolic Syndrome X	ADIPOQ CELA2A	7.00e-04	21	55	2	C0524620
Disease	eye morphology measurement	PAPPA DLX5 GNAL RXRA	7.36e-04	218	55	4	EFO_0007858
Disease	chronic obstructive pulmonary disease (is_marker_for)	ADIPOQ PLAU MUC5AC	7.98e-04	97	55	3	DOID:3083 (is_marker_for)
Disease	sciatic neuropathy (biomarker_via_orthology)	REG3G REG3A PLAU	8.47e-04	99	55	3	DOID:11446 (biomarker_via_orthology)
Disease	Ataxia	GABRA1 GABRA4	9.96e-04	25	55	2	C0004134
Disease	blood nickel measurement	EYS MACROD2 DNER	1.48e-03	120	55	3	EFO_0007583

Protein segments in the cluster

Peptide	Gene	Start	Entry
HPKGYAYIEFATKGS	PABPN1L	186	A6NDY0
NYKHCFSYAIGKPGD	CATSPERE	831	Q5SY80
FTCKGKPVYHFFGTS	ADH4	136	P08319
STGKFHCNIPGLYYF	ADIPOQ	146	Q15848
SLPGHFSSHYKKFFC	AP4B1	306	Q9Y6B7
SPYACFYGASAKKVK	ARAP2	471	Q8WZ64
SFGSRLGCNYYHKPS	CELA2A	236	P08217
AYRKLCPHGSGYTAE	FBN3	2346	Q75N90
DRFSGKKYHFFYGCG	BCO2	471	Q9BYV7
HGYCSPTSASYGKAL	DLX5	56	P56178
HYYGGSAAKFAPSPA	FAM184A	11	Q8NB25
AKYSELGHPFGYLKA	INTS6	356	Q9UL03
RYPSNKGIYLCGHSA	AFMID	151	Q63HM1
PYSGCGKVYGKSSHL	KLF9	146	Q13886
KDCKHPNIVAYFGSY	MAP4K3	66	Q8IVH8
PRLGHSFSLYGNKCY	HCFC2	126	Q9Y5Z7
NGTLKYHFYCPGEAK	EYS	1941	Q5T1H1
LGSYAALHGEFYCKP	LIMD2	76	Q9BT23
PVHGADGKFYTNKCY	SPINK5	936	Q9NQ38
FKNYGAEKYGPHSVC	LMLN	511	Q96KR4
HFFKLKSACGEPAYT	PDE12	536	Q6L8Q7
DAHACPLKFGSYAYT	GABRA1	176	P14867
MDGHACPLKFGSYAY	GABRA4	181	P48169
FGRCHAAVKPGTYYS	MUC5AC	641	P98088
SVGKPHKCGYCGRSY	IKZF1	196	Q13422
SFCKYKCKPGYHVPG	PAPPA	1371	Q13219
HLGGYYFIGCKPDST	FSTL5	656	Q8N475
STATGDGKHYCYPHF	GNAL	336	P38405
LYHCPLYKTGARAGT	DNAH6	4106	Q9C0G6
AYPAFACGSGYVISK	B3GALNT2	406	Q8NCR0
HFGRQCKLAYYGFTK	MARF1	1291	Q9Y4F3
CHGDASKFYGYEALP	HOXC8	81	P31273
GTSYKCLCDPGYHGL	DNER	486	Q8NFT8
HYGVYSCEGCKGFFK	RXRA	146	P19793
PKGSKAYGSPCYALF	REG3G	41	Q6UW15
GFPDKKHKLYGVYCF	HAPLN1	336	P10915
GHAKITCGYDLPAKY	MACROD2	126	A1Z1Q3
PKGSKAYGSHCYALF	REG3A	41	Q06141
AYGSHCYALFLSPKS	REG3A	46	Q06141
KSKTCYEGNGHFYRG	PLAU	66	P00749
AYHLQKSTCGKCGYP	RPL37	26	P61927
TKYANFSEGACKPGY	ST3GAL3	76	Q11203
YFSAKSGVYCGPLKL	SUPV3L1	221	Q8IYB8
HYGVYSCEGCKGFFK	RXRB	216	P28702
HYIGKYKCDCPPGFS	SNED1	636	Q8TER0
GTYYCVKFRKGSPDH	SIRPB1	116	Q5TFQ8
ECAFGKIYKGHLYLP	ROR1	481	Q01973
AYLPGSYGSSHCKLE	SOX15	171	O60248
CYSPKGGNYHSSLGT	SRPX2	71	O60687
HSPGFYTGKPGYKLC	TRAF6	376	Q9Y4K3
EGSDGKKHPYYYSCH	ZNF827	886	Q17R98
CAAPFASHFLYKAGG	TMEM182	136	Q6ZP80
HCGKPYRSKAGLAYH	ZNF512	291	Q96ME7
SCGKAFATGYGLKSH	ZNF76	201	P36508
KPYQCHECGKTFSYG	ZNF184	556	Q99676
GHFGKVSLYCYDPTN	TYK2	906	P29597