Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	homophilic cell adhesion via plasma membrane adhesion molecules	FAT4 PCDHGA10 PCDHGA7 PCDHGA4 CDH23 PTPRT FAT1 CELSR2 PTPRM CDH5 CDHR4	1.15e-06	187	187	11	GO:0007156
GeneOntologyBiologicalProcess	protein dephosphorylation	LILRB1 PTPRT CRY2 STK11 MTMR7 SBF1 PTPRM PTPRZ1 PHLPP1 CDH5 LILRB5	2.31e-05	256	187	11	GO:0006470
GeneOntologyBiologicalProcess	positive regulation of bicellular tight junction assembly	ACVRL1 GDF2 NPHP4	5.92e-05	9	187	3	GO:1903348
GeneOntologyBiologicalProcess	intermediate filament organization	KRT81 KRT83 KRT86 KRT87P KRT23 INA	6.14e-05	75	187	6	GO:0045109
GeneOntologyBiologicalProcess	negative regulation of cell population proliferation	ZBTB7C SPEG RC3H1 MCC E2F3 TSC2 ACVRL1 GDF2 LILRB1 TENT5B JAK2 STK11 PTPRM NFE2 PTPRZ1 ASCL2 ZC3H12D UTP20 INCA1 NOS1 CDH5 AGTPBP1	6.26e-05	961	187	22	GO:0008285
GeneOntologyBiologicalProcess	photoreceptor cell maintenance	USP45 CEP290 CDH23 NPHP4 BBS12	6.54e-05	47	187	5	GO:0045494
GeneOntologyBiologicalProcess	dephosphorylation	LILRB1 PTPRT CRY2 STK11 MTMR7 SBF1 PTPRM FIG4 PTPRZ1 PHLPP1 CDH5 LILRB5	8.15e-05	347	187	12	GO:0016311
GeneOntologyCellularComponent	postsynaptic density, intracellular component	FAM81A USP6 INA NOS1 EXOC4	8.32e-05	49	191	5	GO:0099092
GeneOntologyCellularComponent	Golgi membrane	B3GALT2 AP1S3 SPTBN2 POMGNT1 GALNT12 LMTK3 COG8 AP1S1 OTOF FIG4 MPP4 GALNT9 GOLIM4 RAB11FIP5 AP1S2 ST8SIA4 FUT8 CREB3L2	1.15e-04	721	191	18	GO:0000139
GeneOntologyCellularComponent	AP-1 adaptor complex	AP1S3 AP1S1 AP1S2	1.55e-04	12	191	3	GO:0030121
GeneOntologyCellularComponent	postsynaptic specialization, intracellular component	FAM81A USP6 INA NOS1 EXOC4	1.58e-04	56	191	5	GO:0099091
GeneOntologyCellularComponent	clathrin coat of trans-Golgi network vesicle	AP1S3 AP1S1 AP1S2	5.54e-04	18	191	3	GO:0030130
HumanPheno	Perifollicular hyperkeratosis	KRT81 KRT83 KRT86	7.15e-06	4	63	3	HP:0007468
Domain	Cadherin_CS	FAT4 PCDHGA10 PCDHGA7 PCDHGA4 CDH23 FAT1 CELSR2 CDH5 CDHR4	1.26e-06	109	183	9	IPR020894
Domain	CADHERIN_1	FAT4 PCDHGA10 PCDHGA7 PCDHGA4 CDH23 FAT1 CELSR2 CDH5 CDHR4	1.70e-06	113	183	9	PS00232
Domain	Cadherin	FAT4 PCDHGA10 PCDHGA7 PCDHGA4 CDH23 FAT1 CELSR2 CDH5 CDHR4	1.70e-06	113	183	9	PF00028
Domain	CADHERIN_2	FAT4 PCDHGA10 PCDHGA7 PCDHGA4 CDH23 FAT1 CELSR2 CDH5 CDHR4	1.83e-06	114	183	9	PS50268
Domain	-	FAT4 PCDHGA10 PCDHGA7 PCDHGA4 CDH23 FAT1 CELSR2 CDH5 CDHR4	1.83e-06	114	183	9	2.60.40.60
Domain	CA	FAT4 PCDHGA10 PCDHGA7 PCDHGA4 CDH23 FAT1 CELSR2 CDH5 CDHR4	1.97e-06	115	183	9	SM00112
Domain	Cadherin-like	FAT4 PCDHGA10 PCDHGA7 PCDHGA4 CDH23 FAT1 CELSR2 CDH5 CDHR4	2.12e-06	116	183	9	IPR015919
Domain	Cadherin	FAT4 PCDHGA10 PCDHGA7 PCDHGA4 CDH23 FAT1 CELSR2 CDH5 CDHR4	2.44e-06	118	183	9	IPR002126
Domain	AP_complex_ssu	AP1S3 AP1S1 AP1S2	3.15e-05	7	183	3	IPR016635
Domain	CLAT_ADAPTOR_S	AP1S3 AP1S1 AP1S2	7.44e-05	9	183	3	PS00989
Domain	EIF3C_N_dom	EIF3CL EIF3C	9.55e-05	2	183	2	IPR008905
Domain	eIF-3c_N	EIF3CL EIF3C	9.55e-05	2	183	2	PF05470
Domain	EIF3C	EIF3CL EIF3C	9.55e-05	2	183	2	IPR027516
Domain	Clathrin_sm-chain_CS	AP1S3 AP1S1 AP1S2	1.91e-04	12	183	3	IPR000804
Domain	PH_dom-like	DOK1 SPTBN2 ARHGEF12 TRIOBP MCF2 APBA3 PLEKHG4B JAK2 MTMR7 SBF1 PHLPP1 PLCL1 ARAP2	3.03e-04	426	183	13	IPR011993
Domain	Intermediate_filament_CS	KRT81 KRT83 KRT86 KRT23 INA	3.79e-04	63	183	5	IPR018039
Domain	PH	DOK1 SPTBN2 ARHGEF12 TRIOBP MCF2 PLEKHG4B SBF1 PHLPP1 PLCL1 ARAP2	4.29e-04	278	183	10	SM00233
Domain	PH_DOMAIN	DOK1 SPTBN2 ARHGEF12 TRIOBP MCF2 PLEKHG4B SBF1 PHLPP1 PLCL1 ARAP2	4.42e-04	279	183	10	PS50003
Domain	PH_domain	DOK1 SPTBN2 ARHGEF12 TRIOBP MCF2 PLEKHG4B SBF1 PHLPP1 PLCL1 ARAP2	4.54e-04	280	183	10	IPR001849
Domain	AP_mu_sigma_su	AP1S3 AP1S1 AP1S2	4.72e-04	16	183	3	IPR022775
Domain	Clat_adaptor_s	AP1S3 AP1S1 AP1S2	4.72e-04	16	183	3	PF01217
Domain	-	DOK1 SPTBN2 ARHGEF12 TRIOBP MCF2 APBA3 PLEKHG4B MTMR7 SBF1 PHLPP1 PLCL1 ARAP2	4.92e-04	391	183	12	2.30.29.30
Domain	Filament	KRT81 KRT83 KRT86 KRT23 INA	6.60e-04	71	183	5	SM01391
Domain	IF	KRT81 KRT83 KRT86 KRT23 INA	7.04e-04	72	183	5	PS00226
Domain	Filament	KRT81 KRT83 KRT86 KRT23 INA	7.49e-04	73	183	5	PF00038
Domain	IF	KRT81 KRT83 KRT86 KRT23 INA	9.00e-04	76	183	5	IPR001664
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SEMA6C SZT2 VWA8 SPEG UBE3B MAML1 POMGNT1 TSC2 SRCAP RALGAPA2 TEP1 NPHP4 CDR2L JAK2 CCDC88C HAUS4 FAT1 CELSR2 SBF1 TULP4 ZFYVE26 HERC2 MRPL46	5.00e-08	1105	191	23	35748872
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	RC3H1 SPTBN2 CEP290 RALGAPA2 NPHP4 TMEM200A CRY2 CCDC88C TULP4 LMBR1L FIG4 NUP210 LTN1 CEP152 EXOC4	1.11e-07	493	191	15	15368895
Pubmed	DYRK1a mediates BAFF-induced noncanonical NF-κB activation to promote autoimmunity and B-cell leukemogenesis.	KRT81 KRT83 KRT86 KRT87P TFG EIF3CL EIF3C	1.21e-07	70	191	7	34255829
Pubmed	Novel KRT83 and KRT86 mutations associated with monilethrix.	KRT81 KRT83 KRT86	1.63e-07	3	191	3	25557232
Pubmed	Structure and site of expression of a murine type II hair keratin.	KRT81 KRT83 KRT86	1.63e-07	3	191	3	1372089
Pubmed	Transient expression of mouse hair keratins in transfected HeLa cells: interactions between "hard" and "soft" keratins.	KRT81 KRT83 KRT86	1.63e-07	3	191	3	1712823
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	TPP2 ANK2 SYNE1 SPTBN2 MCC ARHGEF12 TRIOBP TSC2 JAKMIP3 LMTK3 FAM81A CCDC88C AP1S1 INA CELSR2 SBF1 PLCL1 HERC2 NOS1 KLC1	4.10e-07	963	191	20	28671696
Pubmed	Characterization of a 300 kbp region of human DNA containing the type II hair keratin gene domain.	KRT81 KRT83 KRT86 KRT87P	4.22e-07	12	191	4	10692104
Pubmed	AP17 and AP19, the mammalian small chains of the clathrin-associated protein complexes show homology to Yap17p, their putative homolog in yeast.	AP1S3 AP1S1 AP1S2	6.50e-07	4	191	3	2040623
Pubmed	Keratins of the human hair follicle.	KRT81 KRT83 KRT86	6.50e-07	4	191	3	15797458
Pubmed	Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray.	DHX58 ANK2 TRIOBP DBP NPHP4 FICD TULP4 PTPRM HERC2 OSGIN2 CDH5 AGTPBP1	1.14e-06	371	191	12	15747579
Pubmed	Comprehensive analysis of keratin gene clusters in humans and rodents.	KRT81 KRT83 KRT86 KRT87P	1.52e-06	16	191	4	15085952
Pubmed	Cell type-specific Rab32 and Rab38 cooperate with the ubiquitous lysosome biogenesis machinery to synthesize specialized lysosome-related organelles.	AP1S3 AP1S1 AP3B2 AP1S2	1.52e-06	16	191	4	23247405
Pubmed	PERP regulates enamel formation via effects on cell-cell adhesion and gene expression.	KRT81 KRT83 KRT86 KRT87P	3.20e-06	19	191	4	21285247
Pubmed	Interaction of HIV-1 Nef with the cellular dileucine-based sorting pathway is required for CD4 down-regulation and optimal viral infectivity.	AP1S3 AP1S1 AP1S2	3.22e-06	6	191	3	9736718
Pubmed	Crystal structure of the clathrin adaptor protein 1 core.	AP1S3 AP1S1 AP1S2	3.22e-06	6	191	3	15377783
Pubmed	A dileucine motif in HIV-1 Nef acts as an internalization signal for CD4 downregulation and binds the AP-1 clathrin adaptor.	AP1S3 AP1S1 AP1S2	5.61e-06	7	191	3	9811606
Pubmed	Regulator of G protein signaling 12 drives inflammatory arthritis by activating synovial fibroblasts through MYCBP2/KIF2A signaling.	RING1 LTN1 HERC2	5.61e-06	7	191	3	36700049
Pubmed	HIV-1 Nef stabilizes AP-1 on membranes without inducing ARF1-independent de novo attachment.	AP1S3 AP1S1 AP1S2	5.61e-06	7	191	3	16253302
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	TPP2 SPTBN2 CEP290 TRIOBP CCDC77 PTPRT MTMR7 SBF1 PTPRM PTPRZ1 NUP210 LTN1 GOLIM4 PHLPP1 RAB11FIP5 EIF3C HERC2 G6PD AGTPBP1	5.90e-06	1049	191	19	27880917
Pubmed	HIV-1 Nef stabilizes the association of adaptor protein complexes with membranes.	AP1S3 AP1S1 AP1S2	8.95e-06	8	191	3	12486136
Pubmed	A dileucine motif in HIV-1 Nef is essential for sorting into clathrin-coated pits and for downregulation of CD4.	AP1S3 AP1S1 AP1S2	8.95e-06	8	191	3	9811611
Pubmed	Atypical cadherin FAT4 orchestrates lymphatic endothelial cell polarity in response to flow.	FAT4 GOLIM4 CDH5	8.95e-06	8	191	3	32182215
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	FOXRED1 ANK2 KRT83 SYNE1 SPTBN2 CEP290 TRIOBP E2F3 TSC2 JAKMIP3 FAF1 VPS9D1 GDAP1L1 ZNF532 OTOF LRPAP1 EIF3C HERC2 FUT8 AGTPBP1 EXOC4	8.99e-06	1285	191	21	35914814
Pubmed	The highly conserved C-terminal dileucine motif in the cytosolic domain of the human immunodeficiency virus type 1 envelope glycoprotein is critical for its association with the AP-1 clathrin adaptor [correction of adapter].	AP1S3 AP1S1 AP1S2	1.34e-05	9	191	3	11222723
Pubmed	Adaptor protein 1 promotes cross-presentation through the same tyrosine signal in major histocompatibility complex class I as that targeted by HIV-1.	AP1S3 AP1S1 AP1S2	1.34e-05	9	191	3	23678182
Pubmed	Leucine-specific, functional interactions between human immunodeficiency virus type 1 Nef and adaptor protein complexes.	AP1S3 AP1S1 AP1S2	1.34e-05	9	191	3	15681409
Pubmed	Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome.	ANK2 FAM81A RING1 CACNG8 TULP4 SCN1A NOS1 G6PD	1.44e-05	197	191	8	36604605
Pubmed	Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.	HK1 KRT86 UBE3B CEP290 PSMD9 RALGAPA2 KRT87P NPHP4 GUCY2C ZC3H12D LTN1 MMS19 EXOC4	1.61e-05	564	191	13	21565611
Pubmed	Large-scale concatenation cDNA sequencing.	SEMA6C DOK1 ANK2 ABHD3 FAM89B DBP RALGAPA2 WDPCP TRUB2 CCDC88C MMS19 FUT8 CCDC93	1.74e-05	568	191	13	9110174
Pubmed	GGAs: roles of the different domains and comparison with AP-1 and clathrin.	AP1S3 AP1S1 AP1S2	1.90e-05	10	191	3	11694590
Pubmed	HIV-1 Nef disrupts MHC-I trafficking by recruiting AP-1 to the MHC-I cytoplasmic tail.	AP1S3 AP1S1 AP1S2	1.90e-05	10	191	3	15569716
Pubmed	A "double adaptor" method for improved shotgun library construction.	SEMA6C DOK1 ANK2 ABHD3 FAM89B DBP RALGAPA2 WDPCP TRUB2 CCDC88C MMS19 FUT8 CCDC93	1.94e-05	574	191	13	8619474
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	SPTBN2 CEP290 ARHGEF12 SRCAP ZFYVE26 HERC2	2.46e-05	104	191	6	9205841
Pubmed	New consensus nomenclature for mammalian keratins.	KRT81 KRT83 KRT86 KRT87P KRT23	2.57e-05	63	191	5	16831889
Pubmed	Charcot-Marie-Tooth Neuropathy Type 4 – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY	HK1 SBF1 FIG4	2.60e-05	11	191	3	20301641
Pubmed	Tuberin and p27 expression in breast cancer patients with or without BRCA germline mutations.	TSC2 PSMD9	3.00e-05	2	191	2	23689538
Pubmed	Clonal hematopoiesis with JAK2V617F promotes pulmonary hypertension with ALK1 upregulation in lung neutrophils.	ACVRL1 JAK2	3.00e-05	2	191	2	34702814
Pubmed	A missense mutation in the type II hair keratin hHb3 is associated with monilethrix.	KRT83 KRT86	3.00e-05	2	191	2	15744029
Pubmed	G6PD overexpression protects from oxidative stress and age-related hearing loss.	CDH23 G6PD	3.00e-05	2	191	2	33222382
Pubmed	EIF3C Promotes Lung Cancer Tumorigenesis by Regulating the APP/HSPA1A/LMNB1 Axis.	EIF3CL EIF3C	3.00e-05	2	191	2	36157221
Pubmed	Bone morphogenetic protein-9 is a circulating vascular quiescence factor.	ACVRL1 GDF2	3.00e-05	2	191	2	18309101
Pubmed	Blended phenotype of combination of HERC2 and AP3B2 deficiency and Angelman syndrome caused by paternal isodisomy of chromosome 15.	AP3B2 HERC2	3.00e-05	2	191	2	34042275
Pubmed	A variable monilethrix phenotype associated with a novel mutation, Glu402Lys, in the helix termination motif of the type II hair keratin hHb1.	KRT81 KRT86	3.00e-05	2	191	2	9665406
Pubmed	BMP9 Induces Cord Blood-Derived Endothelial Progenitor Cell Differentiation and Ischemic Neovascularization via ALK1.	ACVRL1 GDF2	3.00e-05	2	191	2	26229139
Pubmed	Bone morphogenetic protein‑9 promotes the differentiation of mouse spleen macrophages into osteoclasts via the ALK1 receptor and ERK 1/2 pathways in vitro.	ACVRL1 GDF2	3.00e-05	2	191	2	27748860
Pubmed	Neurons and glia modify receptor protein-tyrosine phosphatase ζ (RPTPζ)/phosphacan with cell-specific O-mannosyl glycans in the developing brain.	POMGNT1 PTPRZ1	3.00e-05	2	191	2	25737452
Pubmed	A new mutation in the type II hair cortex keratin hHb1 involved in the inherited hair disorder monilethrix.	KRT81 KRT86	3.00e-05	2	191	2	9402962
Pubmed	Crystal structure of BMP-9 and functional interactions with pro-region and receptors.	ACVRL1 GDF2	3.00e-05	2	191	2	15851468
Pubmed	A missense mutation in the conserved C2B domain of otoferlin causes deafness in a new mouse model of DFNB9.	CDH23 OTOF	3.00e-05	2	191	2	17967520
Pubmed	BMP-9 regulates the osteoblastic differentiation and calcification of vascular smooth muscle cells through an ALK1 mediated pathway.	ACVRL1 GDF2	3.00e-05	2	191	2	25297851
Pubmed	Type I Interferonopathy due to a Homozygous Loss-of-Inhibitory Function Mutation in STAT2.	USP18 STAT2	3.00e-05	2	191	2	36753016
Pubmed	Recurrent PTPRT/JAK2 mutations in lung adenocarcinoma among African Americans.	PTPRT JAK2	3.00e-05	2	191	2	31844068
Pubmed	Exocyst complex component 3-like 2 (EXOC3L2) associates with the exocyst complex and mediates directional migration of endothelial cells.	EXOC3L2 EXOC4	3.00e-05	2	191	2	21566143
Pubmed	Anti-human activin receptor-like kinase 1 (ALK1) antibody attenuates bone morphogenetic protein 9 (BMP9)-induced ALK1 signaling and interferes with endothelial cell sprouting.	ACVRL1 GDF2	3.00e-05	2	191	2	22493445
Pubmed	Regulation of the TSC pathway by LKB1: evidence of a molecular link between tuberous sclerosis complex and Peutz-Jeghers syndrome.	TSC2 STK11	3.00e-05	2	191	2	15231735
Pubmed	HK1 haemolytic anaemia in association with a neurological phenotype and co-existing CEP290 Meckel-Gruber in a Romani family.	HK1 CEP290	3.00e-05	2	191	2	34532855
Pubmed	Regulation of bone morphogenetic protein 9 (BMP9) by redox-dependent proteolysis.	ACVRL1 GDF2	3.00e-05	2	191	2	25237187
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	RMND5B EDC3 IPO8 UBE3B CEP290 MAML1 MCC CDH23 TSC2 PSMD9 DPP8 NPHP4 EIF3CL CDR2L MED15 HAUS4 BBS12 KLC1 CCDC93 EXOC4	4.37e-05	1321	191	20	27173435
Pubmed	Exome capture reveals ZNF423 and CEP164 mutations, linking renal ciliopathies to DNA damage response signaling.	CEP290 CCDC92 NPHP4	4.48e-05	13	191	3	22863007
Pubmed	Interactions of the cytoplasmic domains of human and simian retroviral transmembrane proteins with components of the clathrin adaptor complexes modulate intracellular and cell surface expression of envelope glycoproteins.	AP1S3 AP1S1 AP1S2	4.48e-05	13	191	3	9882340
Pubmed	Genome-wide survival analysis of age at onset of alcohol dependence in extended high-risk COGA families.	C2orf88 FAM81A UTP20	5.68e-05	14	191	3	24962325
Pubmed	Maturation of postnatally generated olfactory bulb granule cells depends on functional γ-protocadherin expression.	PCDHGA10 PCDHGA7 PCDHGA4	7.07e-05	15	191	3	23515096
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	DPH1 HK1 IPO8 ANK2 VWA8 HACD3 SYNE1 SPTBN2 TRIOBP CNPY2 CCDC77 PCGF6 SBF1 NUP210 RAB11FIP5 LRPAP1 HERC2 MRPL46 AGTPBP1 KLC1 EXOC4	7.53e-05	1487	191	21	33957083
Pubmed	HIV-1 envelope glycoprotein biosynthesis, trafficking, and incorporation.	AP1S3 AP1S1 AP1S2	8.66e-05	16	191	3	21762802
Pubmed	FABP4 activates the JAK2/STAT2 pathway via Rap1a in the homocysteine-induced macrophage inflammatory response in ApoE-/- mice atherosclerosis.	STAT2 JAK2	8.97e-05	3	191	2	34725437
Pubmed	The histone demethylase JMJD2C constitutes a novel NFE2 target gene that is required for the survival of JAK2V617F mutated cells.	JAK2 NFE2	8.97e-05	3	191	2	36709354
Pubmed	Mammalian Auditory Hair Cell Bundle Stiffness Affects Frequency Tuning by Increasing Coupling along the Length of the Cochlea.	TRIOBP CDH23	8.97e-05	3	191	2	29874579
Pubmed	Loss of guanylyl cyclase C (GCC) signaling leads to dysfunctional intestinal barrier.	MYLK3 GUCY2C	8.97e-05	3	191	2	21305056
Pubmed	Homozygous STAT2 gain-of-function mutation by loss of USP18 activity in a patient with type I interferonopathy.	USP18 STAT2	8.97e-05	3	191	2	32092142
Pubmed	BMP9 signaling promotes the normalization of tumor blood vessels.	ACVRL1 GDF2	8.97e-05	3	191	2	32042114
Pubmed	Decreased Colonic Activin Receptor-Like Kinase 1 Disrupts Epithelial Barrier Integrity in Patients With Crohn's Disease.	ACVRL1 GDF2	8.97e-05	3	191	2	32561494
Pubmed	Severe type I interferonopathy and unrestrained interferon signaling due to a homozygous germline mutation in STAT2.	USP18 STAT2	8.97e-05	3	191	2	31836668
Pubmed	Genetic analyses of the mouse deafness mutations varitint-waddler (Va) and jerker (Espnje).	ESPN CDH23	8.97e-05	3	191	2	12209292
Pubmed	MiR-199b-5p Suppresses Tumor Angiogenesis Mediated by Vascular Endothelial Cells in Breast Cancer by Targeting ALK1.	ACVRL1 GDF2	8.97e-05	3	191	2	32082362
Pubmed	Polycystin-1 is required for stereocilia structure but not for mechanotransduction in inner ear hair cells.	ESPN CDH23	8.97e-05	3	191	2	21865467
Pubmed	Rapid Activation of Bone Morphogenic Protein 9 by Receptor-mediated Displacement of Pro-domains.	ACVRL1 GDF2	8.97e-05	3	191	2	26677222
Pubmed	Localization of the mouse Mcf-2 (Dbl) protooncogene within a conserved linkage group on the mouse X chromosome.	MCF2 G6PD	8.97e-05	3	191	2	2265564
Pubmed	Direct stimulation of Jak/STAT pathway by the angiotensin II AT1 receptor.	STAT2 JAK2	8.97e-05	3	191	2	7746328
Pubmed	Sequence data and chromosomal localization of human type I and type II hair keratin genes.	KRT81 KRT86	8.97e-05	3	191	2	7556444
Pubmed	Actin-bundling protein TRIOBP forms resilient rootlets of hair cell stereocilia essential for hearing.	ESPN TRIOBP	8.97e-05	3	191	2	20510926
Pubmed	TGFbeta/BMP type I receptors ALK1 and ALK2 are essential for BMP9-induced osteogenic signaling in mesenchymal stem cells.	ACVRL1 GDF2	8.97e-05	3	191	2	20628059
Pubmed	Sequences and differential expression of three novel human type-II hair keratins.	KRT83 KRT86	8.97e-05	3	191	2	9084137
Pubmed	Structural Basis of the Human Endoglin-BMP9 Interaction: Insights into BMP Signaling and HHT1.	ACVRL1 GDF2	8.97e-05	3	191	2	28564608
Pubmed	JAK2/STAT2/STAT3 are required for myogenic differentiation.	STAT2 JAK2	8.97e-05	3	191	2	18835816
Pubmed	lncRNA ZNF667-AS1 (NR_036521.1) inhibits the progression of colorectal cancer via regulating ANK2/JAK2 expression.	ANK2 JAK2	8.97e-05	3	191	2	32853419
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	TPP2 HDAC11 HK1 ANK2 HACD3 SYNE1 SPTBN2 PHYHIP ARHGEF12 EIF3CL INA SBF1 PTPRZ1 AP3B2 PLCL1 EIF3C NOS1 AGTPBP1 KLC1 EXOC4	1.29e-04	1431	191	20	37142655
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	HACD3 SBF1 NUP210 LTN1 UTP20 MMS19 HERC2	1.34e-04	202	191	7	33005030
Pubmed	Human CIA2A-FAM96A and CIA2B-FAM96B integrate iron homeostasis and maturation of different subsets of cytosolic-nuclear iron-sulfur proteins.	EDC3 TSC2 DPP8 ABCE1 MMS19	1.35e-04	89	191	5	23891004
Pubmed	Transgenic mouse proteomics identifies new 14-3-3-associated proteins involved in cytoskeletal rearrangements and cell signaling.	SPTBN2 TFG INA SBF1 RAB11FIP5 NOS1	1.69e-04	147	191	6	16959763
Pubmed	Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability.	USP45 SZT2 USP6 OTULIN AGTPBP1 CCDC93	1.69e-04	147	191	6	29576527
Pubmed	TRIM11 facilitates chemoresistance in nasopharyngeal carcinoma by activating the β-catenin/ABCC9 axis via p62-selective autophagic degradation of Daple.	MED15 CCDC88C	1.79e-04	4	191	2	32382014
Pubmed	Crossveinless 2 regulates bone morphogenetic protein 9 in human and mouse vascular endothelium.	ACVRL1 GDF2	1.79e-04	4	191	2	22474252
Pubmed	Hereditary Hemorrhagic Telangiectasia	ACVRL1 GDF2	1.79e-04	4	191	2	20301525
Pubmed	Flexible phase adjustment of circadian albumin D site-binding protein (DBP) gene expression by CRYPTOCHROME1.	DBP CRY2	1.79e-04	4	191	2	20551177
Pubmed	AP-1/σ1A and AP-1/σ1B adaptor-proteins differentially regulate neuronal early endosome maturation via the Rab5/Vps34-pathway.	AP1S1 AP1S2	1.79e-04	4	191	2	27411398
Pubmed	Identification of BMP9 and BMP10 as functional activators of the orphan activin receptor-like kinase 1 (ALK1) in endothelial cells.	ACVRL1 GDF2	1.79e-04	4	191	2	17068149
Pubmed	Bone morphogenetic protein-9 inhibits lymphatic vessel formation via activin receptor-like kinase 1 during development and cancer progression.	ACVRL1 GDF2	1.79e-04	4	191	2	24133138
Pubmed	σ1B adaptin regulates adipogenesis by mediating the sorting of sortilin in adipose tissue.	AP1S1 AP1S2	1.79e-04	4	191	2	24928897
Pubmed	BMP9, but not BMP10, acts as a quiescence factor on tumor growth, vessel normalization and metastasis in a mouse model of breast cancer.	ACVRL1 GDF2	1.79e-04	4	191	2	30165893
Interaction	WHAMMP3 interactions	SYNE1 MCC TRIOBP CDR2L HAUS4 INA CEP152 CCDC93 EXOC4	1.93e-06	119	190	9	int:WHAMMP3
Interaction	PCM1 interactions	KRT81 KRT83 KRT86 CEP290 TRIOBP CCDC92 CCDC77 PRC1 FAM81A HAUS4 MTMR7 PHLPP1 CEP152 HERC2 KLC1 EXOC4	3.82e-06	434	190	16	int:PCM1
Cytoband	12q13	KRT81 KRT83 KRT86 KRT87P NFE2	1.26e-05	71	192	5	12q13
Cytoband	Ensembl 112 genes in cytogenetic band chr12q13	KRT81 KRT83 KRT86 CNPY2 ACVRL1 KRT87P STAT2 LMBR1L NFE2	8.07e-05	423	192	9	chr12q13
GeneFamily	Cadherin related	FAT4 CDH23 FAT1 CDHR4	4.39e-06	17	122	4	24
GeneFamily	Protein tyrosine phosphatases, receptor type	PTPRT PTPRM PTPRZ1	3.65e-04	21	122	3	813
GeneFamily	Bardet-Biedl syndrome associated\|BBSome	CEP290 WDPCP BBS12	3.65e-04	21	122	3	980
GeneFamily	CD molecules\|Inhibitory leukocyte immunoglobulin like receptors	LILRB1 LILRB5	4.46e-04	5	122	2	1182
GeneFamily	Ferlin family	OTOF FER1L4	6.66e-04	6	122	2	828
GeneFamily	Keratins, type II	KRT81 KRT83 KRT86	7.79e-04	27	122	3	609
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	SPTBN2 TRIOBP PLEKHG4B SBF1 PHLPP1 ARAP2	2.75e-03	206	122	6	682
GeneFamily	PDZ domain containing	ARHGEF12 APBA3 PSMD9 MPP4 NOS1	3.71e-03	152	122	5	1220
CoexpressionAtlas	facebase_RNAseq_e10.5_NeuroEpith_central_2500_K4	EFCAB5 HDAC11 IPO8 ANK2 SPTBN2 CEP290 TRIOBP HAT1 E2F3 CCDC92 LMTK3 ST7L CCDC77 PRC1 RALGAPA2 NPHP4 FAF1 RING1 CRY2 CDR2L CCDC88C PCGF6 FAT1 MTMR7 CELSR2 PTPRZ1 AP3B2 PHLPP1 AP1S2 MMS19 MTO1 ST8SIA4 FUT8	1.35e-07	1370	188	33	facebase_RNAseq_e10.5_NeuroEpith_central_2500_K4
ToppCell	Children_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FAT4 SYNE1 MCC ARHGEF12 ACVRL1 PTPRM GFOD1 STARD9 CDH5	1.47e-07	190	192	9	0e9847d7f49b2236b8a191e1a7df37556351ba9e
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated\|COVID-19_Mild / Disease, condition lineage and cell class	FAT4 SYNE1 ARHGEF12 SRCAP EIF3CL GFOD1 EIF3C DTHD1 ARAP2	2.27e-07	200	192	9	2281debd86e5d92e8fe0397aec9ef670800f7471
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SZT2 RC3H1 MAML1 CDR2L PTPRM OXSM ST8SIA4 RBM43	1.58e-06	187	192	8	3699d5e71d779da922920aa3160895db187bf81b
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SZT2 RC3H1 MAML1 CDR2L PTPRM OXSM ST8SIA4 RBM43	1.58e-06	187	192	8	033ba52c0c2f9978784947098fa697368ae44834
ToppCell	Children_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FAT4 SYNE1 MCC ARHGEF12 PTPRM GFOD1 STARD9 CDH5	1.85e-06	191	192	8	f229abf69a1217194f74b0502486907e07dba989
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	B3GALT2 PTPRT FAT1 PTPRM SCN1A GOLIM4 AP1S2 NOS1	2.08e-06	194	192	8	52aebb0b563e2c2058e7f0554ae870e47692b163
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	B3GALT2 PTPRT FAT1 PTPRM SCN1A GOLIM4 AP1S2 NOS1	2.08e-06	194	192	8	bd06e2b8d8c06cddf2e4f58849b86e09013acae1
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SYNE1 RALGAPA2 SEMA3D PTPRM GFOD1 EXOC3L2 CDH5 AGTPBP1	2.24e-06	196	192	8	8f2031b1a9232c389517fbf3c29f47f9468b0077
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SYNE1 RALGAPA2 SEMA3D PTPRM GFOD1 EXOC3L2 CDH5 AGTPBP1	2.24e-06	196	192	8	48b4a9cea97a55190217deaf51bf867608c5a9a7
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SYNE1 RALGAPA2 SEMA3D PTPRM GFOD1 EXOC3L2 CDH5 AGTPBP1	2.24e-06	196	192	8	473980c827443464d08a0be28c53e3536369b12a
ToppCell	COVID-19-lung-Capillary_Aerocytes\|lung / Disease (COVID-19 only), tissue and cell type	SYNE1 MCC ARHGEF12 ACVRL1 RALGAPA2 PTPRM STARD9 CDH5	2.24e-06	196	192	8	4ac4073380d939a73cec7413e9f3f5ef616d2924
ToppCell	tumor_Lung-T/NK_cells-CD8_low_T\|T/NK_cells / Location, Cell class and cell subclass	STAB2 E2F3 CACNG8 GUCY2C NFE2 MPP4 DTHD1	2.82e-06	142	192	7	eaf08a0dbacc9ebbd54e377922e76d8ba854dcb8
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Ntn1_Npy2r\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	FAT4 VRK1 PTPRT FAT1 PTPRM PTPRZ1 AP1S2	4.43e-06	152	192	7	8ff5a178a8f3550d89a003c0858820aab3773386
ToppCell	droplet-Kidney-nan-3m-Epithelial-kidney_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAM89B CDR2L OTOF NFE2 ZC3H12D AP1S2 ST8SIA4	8.55e-06	168	192	7	f45dbcd7753117a3e41e1412bce2100d52fa7fd0
ToppCell	wk_15-18-Endothelial-Blood_vessel_endothelial-arterial_endo\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	CFAP36 ACVRL1 PTPRM GFOD1 FUT8 NOS1 CDH5	1.03e-05	173	192	7	3a9e9a09b3eeb37cbe56d650e112a8398879477f
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-regulatory_T_cell-regulatory_T_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PGS1 C2orf88 ARHGEF38 CCDC92 MTMR7 ASCL2 ZC3H12D	1.20e-05	177	192	7	fd4a297e519b3959811a462d63feebff76429031
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SPEG HAT1 NPHP4 PTPRZ1 GOLIM4 PLCL1 HSPB2	1.20e-05	177	192	7	4553ee8cd9c24db6511b09fe49ed11a89e7cde9e
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-regulatory_T_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PGS1 C2orf88 ARHGEF38 CCDC92 MTMR7 ASCL2 ZC3H12D	1.20e-05	177	192	7	e995230ef207dcd87eab4550617589016ffa9970
ToppCell	E16.5-samps-Endothelial-Immature_fetal_endothelial-Intermediate_Endothelial\|E16.5-samps / Age Group, Lineage, Cell class and subclass	STAB2 ACVRL1 CDR2L PTPRM RAB11FIP5 CDH5 ARAP2	1.44e-05	182	192	7	fec1caf867b1dc87b24504d895ee1a27df78062e
ToppCell	PND07-Epithelial-Epithelial_Airway-Neurosecretory-PNEC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ESPN SPTBN2 CCDC92 JAKMIP3 GDAP1L1 INA AP3B2	1.54e-05	184	192	7	3e5c68a99c10eb1ddc1048bea4aa9f6b8e2746ff
ToppCell	PND07-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ESPN SPTBN2 CCDC92 JAKMIP3 GDAP1L1 INA AP3B2	1.54e-05	184	192	7	1e2f0cec50475a1cf2973a5082826bbc60fc9a68
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	C12orf56 CCDC88C OLFM3 GFOD1 FUT8 CDH5 AGTPBP1	1.77e-05	188	192	7	c2c51c6526defe2600302901159b8abbb58d7595
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTPRT FAT1 PTPRM GOLIM4 AP1S2 ST8SIA4 NOS1	1.77e-05	188	192	7	3139540a656c0436b2123ea50741ff8d00112165
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	C12orf56 ACVRL1 OLFM3 PTPRM GFOD1 FUT8 CDH5	1.83e-05	189	192	7	12b6f1c3bf526b90e112374bf937701f645c5780
ToppCell	facs-Lung-EPCAM-24m-Epithelial-Neuroendocrine\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ESPN HDAC11 SPTBN2 LMTK3 GDAP1L1 INA AP3B2	1.96e-05	191	192	7	501d4f6ad389d9ac5051d4247b9bd3da96f713f9
ToppCell	E16.5-samps-Endothelial-Immature_fetal_endothelial\|E16.5-samps / Age Group, Lineage, Cell class and subclass	STAB2 ACVRL1 CDR2L PTPRM NUP210 CDH5 ARAP2	1.96e-05	191	192	7	44c596984c6196f6014e0e405dbe5560841e54ff
ToppCell	PCW_13-14-Epithelial-Epithelial_neuroendo-epi_neuroendocrine2[NE2]_(12)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ESPN PKD2L1 MTMR7 OLFM3 INA TMEM132D NUP210	1.96e-05	191	192	7	19832ddd559a353e1618fe853d79e3edfec6dcda
ToppCell	E16.5-samps-Endothelial\|E16.5-samps / Age Group, Lineage, Cell class and subclass	STAB2 ACVRL1 CDR2L PTPRM NUP210 CDH5 ARAP2	1.96e-05	191	192	7	e7521d4d24f016d4e531cd492a7a69604f0c9e6f
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ZBTB7C ANK2 SYNE1 SPEG FAT1 GALNT9 PLCL1	1.96e-05	191	192	7	7853ac7dff649150e6ff27cd4c8cf7c1fc034ed4
ToppCell	facs-Lung-EPCAM-24m-Epithelial-lung_neuroendocrine_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ESPN HDAC11 SPTBN2 LMTK3 GDAP1L1 INA AP3B2	1.96e-05	191	192	7	8e06cc61eaff1796c2ce014074029408ba88d561
ToppCell	facs-Pancreas-Endocrine-3m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFAP36 CRY2 MTMR7 TULP4 AP3B2 GOLIM4 AP1S2	1.96e-05	191	192	7	657297cd19d05a7e7bb74fc3a086fbd95f47aae4
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-4_LAMP5_DUSP4_(Lamp5_Rosehip)\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	B3GALT2 PTPRT FAT1 PTPRM SCN1A GOLIM4 AP1S2	2.03e-05	192	192	7	63d1b3efe93e5ff939278ebe40bacb38218ea09b
ToppCell	Control-Endothelial-Endothelial\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FAT4 MCC ACVRL1 RALGAPA2 PTPRM ST8SIA4 CDH5	2.10e-05	193	192	7	aff0649c73c634bc6ff0dc7759b4693a9236bf05
ToppCell	Control-Endothelial\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FAT4 MCC ACVRL1 RALGAPA2 PTPRM ST8SIA4 CDH5	2.10e-05	193	192	7	c5f9fe03e64c211d4bcd4959e5b32f14841e336a
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	C12orf56 ACVRL1 OLFM3 PTPRM GFOD1 FUT8 CDH5	2.10e-05	193	192	7	0b328f725f6feba263783eaca60c142e80df90f3
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FAT4 SYNE1 ACVRL1 PTPRM GFOD1 EXOC3L2 CDH5	2.10e-05	193	192	7	456aa8a8f1f9cbba0bd618a5f623909079c0f56b
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FAT4 C12orf56 ACVRL1 OLFM3 PTPRM GFOD1 CDH5	2.17e-05	194	192	7	b0c15e7e4bcf30856fb628dedd7ba82df33489f5
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SYNE1 ACVRL1 PTPRM GFOD1 AP1S2 EXOC3L2 CDH5	2.24e-05	195	192	7	23ced69fd904f1d4114b1a7f99f4b5f65ea8824b
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW08-Neuronal-GABAergic_neurons\|GW08 / Sample Type, Dataset, Time_group, and Cell type.	CEP290 ARHGEF12 SRCAP RING1 PLEKHG4B ASCL2 SCN1A	2.39e-05	197	192	7	e1a80c1aa7f7e83f5d19a40fe37db5c5a6c25685
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SEMA3D PTPRM GFOD1 STARD9 PHLPP1 EXOC3L2 CDH5	2.39e-05	197	192	7	cd509e49bbdbf991cc5913960ff3ef275ad40628
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SEMA3D PTPRM GFOD1 STARD9 PHLPP1 EXOC3L2 CDH5	2.39e-05	197	192	7	412cb5f37df57121ddd1492021445479c7cbccbf
ToppCell	ASK428-Endothelial\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	FAT4 STAB2 MCC ACVRL1 SEMA3D RAB11FIP5 CDH5	2.47e-05	198	192	7	d69d0ff115298596173a4278897a65007a71f5df
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal-6\|World / Primary Cells by Cluster	B3GALT2 ANK2 CEP290 ARHGEF12 PTPRT CACNG8 INA	2.55e-05	199	192	7	1b1bccf4293f11048709d15a3c892c0edf3da3d2
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	B3GALT2 ANK2 GDAP1L1 INA PTPRZ1 AP1S2 NOS1	2.55e-05	199	192	7	47466253069d4b1b8f13ce3210f434e60753b38a
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal\|World / Primary Cells by Cluster	B3GALT2 ANK2 CEP290 ARHGEF12 PTPRT CACNG8 INA	2.55e-05	199	192	7	4bee94c116c0da5eba951cb4cea7cc9dcdd6e30f
ToppCell	Control_saline-Endothelial-Endothelial-Activated_Alv_Cap\|Control_saline / Treatment groups by lineage, cell group, cell type	USP18 DHX58 ARHGEF12 ACVRL1 PTPRM CDH5 KLC1	2.64e-05	200	192	7	be55cef682ba87250dad97689332c8820b3a7420
ToppCell	PND07-28-samps-Endothelial-Postnatal_endothelial-endothelial_cells_D\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	MROH2A ACVRL1 FICD PTPRM CDH5 KLC1	3.26e-05	140	192	6	b9aeb7dda7f377b580dd8a44912f300721437387
ToppCell	Severe-B_intermediate-14\|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)	ANK2 DBP COG8 USP6 MYLK3 ASCL2	3.53e-05	142	192	6	f9cbc266fcea19bec504be4f3a28d1173c6b2e3c
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Rspo1_Itga4\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	PLCZ1 FAT4 SEMA3D OLFM3 PTPRZ1 AP1S2	3.82e-05	144	192	6	7de962346ba9653d90dd13bb7d977fe44d200bba
ToppCell	Tracheal-NucSeq-Immune_Myeloid-Macrophage_other-Macro_interstitial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CDH23 RAB20 LILRB1 AXDND1 OSGIN2 ST8SIA4	3.97e-05	145	192	6	778655fffd73df101e656154a41b478a1b695116
ToppCell	356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	FOXRED1 PCDHGA10 SPEG FAM81A PTPRM PHLPP1	4.80e-05	150	192	6	b6f1fc62d08199fed6156c7cd32f66d9926531b5
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Plch2_Dock5\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	VRK1 HAUS4 FAT1 PTPRM PTPRZ1 NOS1	5.17e-05	152	192	6	fed80b467ec9e30c7f98bed6cc4f8c583b715e9e
ToppCell	Ciliated_cells-B-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	PLCZ1 NWD1 FAM81A PTPRT DTHD1 CDHR4	7.87e-05	164	192	6	0e9961acbb1d6c0089e6805ba6756736fa4d8bed
ToppCell	droplet-Lung-3m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2-17-52\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DHX58 OTOF NFE2 GALNT9 PLCL1 BBS12	8.41e-05	166	192	6	de319c960b0cd90b294f677d1ea1b013a2ce2d53
ToppCell	Cerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	B3GALT2 SEMA6C SPTBN2 LMTK3 GFOD1 SCN1A	8.70e-05	167	192	6	9efb9511a211d0824bb97f82c1a5860c43d2138f
ToppCell	Cerebellum-Neuronal-Inhibitory\|Cerebellum / BrainAtlas - Mouse McCarroll V32	B3GALT2 SEMA6C SPTBN2 LMTK3 GFOD1 SCN1A	8.70e-05	167	192	6	904c613aac3f9919a432b110bb1dcc832b5aec0a
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SPEG OLFM3 PTPRM GFOD1 NOS1 CDH5	9.29e-05	169	192	6	c7fc3a8c44f07c557b60d469717b66e2f5863d38
ToppCell	10x_3'_v2v3-Non-neoplastic-Lymphoid-NK-NK-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	AP1S3 KRT81 KRT86 TMEM200A GFOD1 G6PD	9.59e-05	170	192	6	aaf29c2d4de172d366cbfc863bc741941667dde1
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-intermediate_neuroendocrine\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	ANK2 SPTBN2 USP6 MTMR7 INA AP3B2	9.91e-05	171	192	6	b7cddb8f726a43fb8a37f3e67a3f722e2178fd7a
ToppCell	facs-Marrow-B-cells-24m-Hematologic-hematopoietic_stem_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C5orf52 CDH23 PKD2L1 GDAP1L1 ZC3H12D CREB3L2	1.02e-04	172	192	6	a7fd4d61fb5017dce001d69d6b9a01e6cdf58828
ToppCell	COVID-19-Heart-EC_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FAT4 MCC PTPRM GFOD1 FUT8 CDH5	1.27e-04	179	192	6	2a53d94f6c30bf887dfe88f1693ea057218c852d
ToppCell	3'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Glia_2_(ELN+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	B3GALT2 RAB20 CELSR2 PTPRZ1 AP1S2 HSPB2	1.35e-04	181	192	6	a436e7e4c36403257ea90160a58ca0d6d7c0cdfc
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZBTB7C PHYHIP CCDC92 GDF2 SEMA3D MYLK3	1.35e-04	181	192	6	330d4322f4c4373f706273c1f4e218b59051b7fd
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZBTB7C PHYHIP CCDC92 GDF2 SEMA3D MYLK3	1.35e-04	181	192	6	3f4d5d79c1286614514b0e8134079d6128a2a23e
ToppCell	PND07-28-samps-Endothelial-Postnatal_endothelial-capillary_endothelial_Hpgd-CA4_high\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	ACVRL1 CDR2L CELSR2 ST8SIA4 CDH5 ARAP2	1.35e-04	181	192	6	9cd5e5c285c2b628db9d59709af053defd7c0aff
ToppCell	Epithelial-lung_neuroendocrine_cell_(PNEC)\|World / Lineage, Cell type, age group and donor	ANK2 MTMR7 OLFM3 INA TMEM132D AP3B2	1.39e-04	182	192	6	57bf4ffb304324e2e392e196336a530d9f78fe0d
ToppCell	E18.5-samps-Endothelial-Mature_fetal_endothelial\|E18.5-samps / Age Group, Lineage, Cell class and subclass	ACVRL1 CDR2L PTPRM ST8SIA4 CDH5 ARAP2	1.39e-04	182	192	6	7af3b2029b7f55b923d5a4b764d4292f4ea48599
ToppCell	E18.5-samps-Endothelial\|E18.5-samps / Age Group, Lineage, Cell class and subclass	ACVRL1 CDR2L PTPRM ST8SIA4 CDH5 ARAP2	1.39e-04	182	192	6	e2d799e6e7526176a6fe6515b8fbe4d83d3a3ea1
ToppCell	E16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-matrix_-_mature\|E16.5-samps / Age Group, Lineage, Cell class and subclass	FAT4 PCDHGA4 CEP290 CDH23 MPP4	1.41e-04	115	192	5	c3f6efb90d5ee01af831f65e240505faa6a71dc0
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ZBTB7C MCC PHYHIP ARHGEF12 FAM81A GOLIM4	1.43e-04	183	192	6	3c516fe5083f02bad1f464ed284010b4131a833c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ZBTB7C MCC PHYHIP ARHGEF12 FAM81A GOLIM4	1.43e-04	183	192	6	9c2689d76fc6d30f5ab093428aa669d0a98953cf
ToppCell	COVID-19-Heart-EC_3\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ZBTB7C RALGAPA2 SEMA3D PTPRM GFOD1 CDH5	1.43e-04	183	192	6	ff95382cfed592190d0636d2b750328471f82e0d
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT4 NWD1 PKD2L1 PTPRM PTPRZ1 CDH5	1.52e-04	185	192	6	f98af3146ec2f44c30d31a662fb9c4fa3ca4f706
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L3-4_RORB_RPS3P6\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FAT4 ZBTB7C PTPRZ1 CEP152 ST8SIA4 ARAP2	1.52e-04	185	192	6	10da5c2a92bfb3248d3f6f94a0933996326cf590
ToppCell	PCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_neuroendocrine2[NE2]_(12)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ESPN PKD2L1 MTMR7 INA TMEM132D ASCL2	1.57e-04	186	192	6	c7983281a290201567b398e9ea6baddb96c692bb
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ZBTB7C SYNE1 SPEG FAM81A FAT1 PLCL1	1.57e-04	186	192	6	4780af76237d7af2abbe2d8d5530cdf53e3ed0b7
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ANK2 MTMR7 OLFM3 INA TMEM132D AP3B2	1.57e-04	186	192	6	b45cce768e4bf91da194fd9660cab7520dfb15ac
ToppCell	COVID-19-Heart-EC_2\|Heart / Disease (COVID-19 only), tissue and cell type	FAT4 CCDC88C PTPRM GFOD1 FUT8 CDH5	1.61e-04	187	192	6	40ffc06a3e3251d9b12da390210d3e045af7537a
ToppCell	Control-Endothelial_cells-Arterial_endothelial_cells\|Control / group, cell type (main and fine annotations)	MCC RALGAPA2 PTPRM GFOD1 NOS1 CDH5	1.61e-04	187	192	6	81affaab3fe3e1daea45ada6445e906ddd33950e
ToppCell	COVID-19-lung-Artery_EC\|lung / Disease (COVID-19 only), tissue and cell type	FAT4 MCC RALGAPA2 PTPRM GFOD1 NOS1	1.66e-04	188	192	6	eecd7482b3c97d7f49993cb17edfab30c61232fc
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ANK2 MTMR7 OLFM3 INA TMEM132D AP3B2	1.66e-04	188	192	6	c4c3b21ab723b0e9beff9ec84f8d68485f771528
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-4_LAMP5_DUSP4_(Lamp5_Rosehip)\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	B3GALT2 PTPRT FAT1 PTPRM GOLIM4 AP1S2	1.71e-04	189	192	6	979b7fa947538aa7ca4a219263da2575869a2caa
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPTBN2 PHYHIP OLFM3 INA SCN1A NOS1	1.71e-04	189	192	6	f57200c93d39c9bce1adba0a6a1c178c028dd86b
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ZBTB7C SEMA3D PTPRM GFOD1 EXOC3L2 CDH5	1.76e-04	190	192	6	656483751e4bf137e4e4bfb2a03a478a8f7fcb63
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	B3GALT2 PTPRT FAT1 PTPRM GOLIM4 AP1S2	1.76e-04	190	192	6	56cc761e50fddfb5366391518b4d8e16589b6b42
ToppCell	COVID-19-lung-Artery_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FAT4 MCC RALGAPA2 PTPRM GFOD1 NOS1	1.76e-04	190	192	6	07b675befcd1d0a9c90cb17b5d22323468325d51
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	B3GALT2 PTPRT FAT1 PTPRM GOLIM4 AP1S2	1.76e-04	190	192	6	25d4b591f75c26e404a34c42f1742d580af6598d
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_artery\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FAT4 MCC PTPRM GFOD1 NOS1 CDH5	1.76e-04	190	192	6	f6c38d197fd9d69a4f97cb2e72cd4747984c1a86
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-AEC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MCC RALGAPA2 PTPRM GFOD1 NOS1 CDH5	1.81e-04	191	192	6	50601ef0a5a8f2c2120922989e08e85bf2d9b4ab
ToppCell	facs-Pancreas-Endocrine-3m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFAP36 CRY2 MTMR7 TULP4 GOLIM4 AP1S2	1.81e-04	191	192	6	b3de0393d6510543533cd851e47a0f95739a0e4e
ToppCell	Entopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	SPTBN2 CEP290 PHYHIP OLFM3 INA GALNT9	1.81e-04	191	192	6	5d24022cec293bc8d9e978ae99a109e660bb8f83
ToppCell	Entopeduncular-Neuronal-Inhibitory\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	SPTBN2 CEP290 PHYHIP OLFM3 INA GALNT9	1.81e-04	191	192	6	73dae4cdea86aec62393ad7303dc7375a6b3fc86
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ZBTB7C CDH23 RALGAPA2 SEMA3D PTPRM EXOC3L2	1.86e-04	192	192	6	1ee4783051ec94ea94600f040edcb385fc4289f1
ToppCell	droplet-Fat-Scat-18m-Epithelial-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HDAC11 SPTBN2 TMEM79 MTMR7 CELSR2 FER1L4	1.86e-04	192	192	6	4098b5170c9995718758a082d1b8bcb86d5a289e
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	B3GALT2 PTPRT FAT1 PTPRM GOLIM4 AP1S2	1.86e-04	192	192	6	f6ec683b2133b3095a1fcc06ca8605cf38f774b5
ToppCell	droplet-Fat-Scat-18m-Epithelial\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HDAC11 SPTBN2 TMEM79 MTMR7 CELSR2 FER1L4	1.86e-04	192	192	6	936028fe851e8dd2b906df0210acc574c017b499
ToppCell	droplet-Fat-Scat-18m-Epithelial-epithelial_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HDAC11 SPTBN2 TMEM79 MTMR7 CELSR2 FER1L4	1.86e-04	192	192	6	62e55ed0d46b2e7b07dc42399972a099576cbc5f
ToppCell	wk_08-11-Epithelial-PNS-KCNIP4+_neuron\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	ANK2 GDAP1L1 OLFM3 INA AP3B2 NOS1	1.86e-04	192	192	6	53642c88891f4e4e14b1740c5ced759b7d8b3572
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-4_LAMP5_DUSP4_(Lamp5_Rosehip)\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	B3GALT2 PTPRT FAT1 PTPRM GOLIM4 AP1S2	1.86e-04	192	192	6	342842378c20267c5044bdd622515e8b9f895623
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_NOS-6\|TCGA-Stomach / Sample_Type by Project: Shred V9	USP18 AP1S3 HAT1 TFG FAM81A JAK2	1.86e-04	192	192	6	4e689bca7a242f8482e25f273656e2caba8821c0
Disease	Colorectal Carcinoma	ANK2 SYNE1 SPTBN2 MCC HAT1 GALNT12 TFG PTPRT STK11 FAT1 GDAP1L1 MYLK3 GUCY2C ABCE1 ST8SIA4 CDH5 AGTPBP1 CCDC93 EXOC4	1.36e-07	702	188	19	C0009402
Disease	MONILETHRIX	KRT81 KRT83 KRT86	2.55e-07	3	188	3	158000
Disease	Beaded hair	KRT81 KRT83 KRT86	2.55e-07	3	188	3	cv:C0546966
Disease	monilethrix (is_implicated_in)	KRT81 KRT83 KRT86	2.55e-07	3	188	3	DOID:0050472 (is_implicated_in)
Disease	Monilethrix	KRT81 KRT83 KRT86	1.01e-06	4	188	3	C0546966
Disease	hair disease (is_implicated_in)	KRT81 KRT86	4.04e-05	2	188	2	DOID:421 (is_implicated_in)
Disease	Charcot-Marie-Tooth disease type 4	HK1 SBF1 FIG4	6.95e-05	13	188	3	cv:C4082197
Disease	Ciliopathies	CEP290 CDH23 TSC2 NPHP4 WDPCP BBS12	7.64e-05	110	188	6	C4277690
Disease	prefrontal cortex cytoarchtiectural measurement	MCC PLCL1	1.21e-04	3	188	2	EFO_0006913
Disease	Telangiectasia, Hereditary Hemorrhagic, Type 1	ACVRL1 GDF2	1.21e-04	3	188	2	C4551861
Disease	Bardet-Biedl syndrome 1 (disorder)	CEP290 WDPCP BBS12	1.62e-04	17	188	3	C2936862
Disease	Bardet-Biedl syndrome	CEP290 WDPCP BBS12	1.94e-04	18	188	3	cv:C0752166
Disease	hereditary hemorrhagic telangiectasia (is_implicated_in)	ACVRL1 GDF2	2.40e-04	4	188	2	DOID:1270 (is_implicated_in)
Disease	Hereditary hemorrhagic telangiectasia	ACVRL1 GDF2	2.40e-04	4	188	2	cv:C0039445
Disease	Hereditary hemorrhagic telangiectasia	ACVRL1 GDF2	2.40e-04	4	188	2	C0039445
Disease	insomnia, insomnia measurement	CEP152 PLCL1	2.40e-04	4	188	2	EFO_0004698, EFO_0007876
Disease	Nonsyndromic Hearing Loss and Deafness, Autosomal Recessive	ESPN TRIOBP CDH23 OTOF	3.16e-04	51	188	4	cv:CN043650
Disease	congenital nonspherocytic hemolytic anemia (is_implicated_in)	HK1 G6PD	3.99e-04	5	188	2	DOID:2861 (is_implicated_in)
Disease	Charcot-Marie-Tooth disease (implicated_via_orthology)	MTMR7 GDAP1L1 FIG4	4.67e-04	24	188	3	DOID:10595 (implicated_via_orthology)
Disease	mental development measurement	PCDHGA10 PCDHGA7 PCDHGA4	5.28e-04	25	188	3	EFO_0008230
Disease	smoking status measurement, low density lipoprotein cholesterol measurement	ASCL2 CREB3L2	8.30e-04	7	188	2	EFO_0004611, EFO_0006527
Disease	Senior-Loken syndrome (is_implicated_in)	CEP290 NPHP4	8.30e-04	7	188	2	DOID:0050576 (is_implicated_in)
Disease	limb-girdle muscular dystrophy (implicated_via_orthology)	OTOF FER1L4	8.30e-04	7	188	2	DOID:11724 (implicated_via_orthology)
Disease	Renal dysplasia and retinal aplasia	CEP290 NPHP4	8.30e-04	7	188	2	cv:C0403553
Disease	disease recurrence, malaria	PTPRT PTPRM	1.10e-03	8	188	2	EFO_0001068, EFO_0004952
Disease	lymphocyte count	NWD1 PCDHGA10 PCDHGA7 PCDHGA4 CDH23 PKD2L1 E2F3 CCDC92 DBP ACVRL1 PTPRT FAF1 STK11 SEMA3D GFOD1 PHLPP1 EXOC3L2 ST8SIA4 BBS12 CCDC63	1.12e-03	1464	188	20	EFO_0004587
Disease	IGF-1 measurement	STAB2 RC3H1 SPTBN2 E2F3 SRCAP TENT5B JAK2 ASCL2 STARD9 CREB3L2	1.22e-03	488	188	10	EFO_0004627
Disease	Hydrocephalus	CCDC88C EXOC3L2	1.41e-03	9	188	2	C0020255
Disease	Nonsyndromic genetic hearing loss	ESPN TRIOBP CDH23 OTOF	1.43e-03	76	188	4	cv:C5680182
Disease	Autoinflammatory disorder	USP18 AP1S3 OTULIN	1.43e-03	35	188	3	C3860213
Disease	leukocyte immunoglobulin-like receptor subfamily B member 2 measurement	LILRB1 LILRB5	2.14e-03	11	188	2	EFO_0008209
Disease	Enzymopathy	HK1 G6PD	2.14e-03	11	188	2	C0520572
Disease	Charcot-Marie-Tooth disease	HK1 SBF1 FIG4	2.43e-03	42	188	3	cv:C0007959
Disease	age at onset, alcohol dependence	C2orf88 FAM81A UTP20	2.43e-03	42	188	3	EFO_0004847, MONDO_0007079
Disease	complement C1q tumor necrosis factor-related protein 1 measurement	CDH23 CELSR2	2.56e-03	12	188	2	EFO_0801493
Disease	Renal dysplasia and retinal aplasia (disorder)	CEP290 NPHP4	2.56e-03	12	188	2	C0403553
Disease	granulins measurement	CDH23 CELSR2	2.56e-03	12	188	2	EFO_0008141
Disease	DEAFNESS, AUTOSOMAL RECESSIVE (disorder)	TRIOBP CDH23	3.01e-03	13	188	2	C1846647
Disease	Pneumoconiosis	CDH23 PTPRZ1	3.49e-03	14	188	2	C0032273
Disease	Bagassosis	CDH23 PTPRZ1	3.49e-03	14	188	2	C0004681
Disease	2-oxo-hept-3-ene-1,7-dioate hydratase activity	ACVRL1 GDF2	3.49e-03	14	188	2	C1150929
Disease	anemia (is_implicated_in)	HK1 G6PD	3.49e-03	14	188	2	DOID:2355 (is_implicated_in)
Disease	Meckel-Gruber syndrome	CEP290 WDPCP	4.01e-03	15	188	2	C0265215
Disease	hepatic encephalopathy (biomarker_via_orthology)	NOS1 G6PD	4.01e-03	15	188	2	DOID:13413 (biomarker_via_orthology)
Disease	coronary artery disease	FAT4 DHX58 UBE3B ARHGEF12 PKD2L1 CCDC92 CNPY2 ACVRL1 CELSR2 GFOD1 TMEM132D NUP210 ZC3H12D PLCL1 EXOC3L2 ST8SIA4	4.22e-03	1194	188	16	EFO_0001645
Disease	monocyte count	STAB2 ZBTB7C IPO8 SZT2 UBE3B SPTBN2 ARHGEF12 CDH23 PKD2L1 DPP8 ACVRL1 NFE2 ASCL2 EXOC3L2 ST8SIA4 DTHD1 CREB3L2	4.77e-03	1320	188	17	EFO_0005091
Disease	brain volume measurement	EFCAB5 SZT2 KRT86 MCC TRIOBP GALNT12 FAF1 PCGF6 INA PLCL1	5.03e-03	595	188	10	EFO_0006930
Disease	muscular dystrophy (is_implicated_in)	SYNE1 POMGNT1	5.16e-03	17	188	2	DOID:9884 (is_implicated_in)
Disease	cyclic adenosine monophosphate measurement	PTPRM ARAP2	5.16e-03	17	188	2	EFO_0010473
Disease	Familial primary pulmonary hypertension	ACVRL1 GDF2	5.16e-03	17	188	2	C0340543
Disease	Meckel syndrome type 1	CEP290 WDPCP	5.78e-03	18	188	2	C3714506
Disease	low density lipoprotein particle size measurement	PGS1 PKD2L1 CELSR2	6.07e-03	58	188	3	EFO_0008593

Protein segments in the cluster

Peptide	Gene	Start	Entry
QALVAELHRRALVEY	EXOC3L2	221	Q2M3D2
EHRDLISRPNLSVIY	ADAM5	271	Q6NVV9
SILREVDEQYHALLE	CDR2L	351	Q86X02
RIVIEYVDRIIFHEN	CFI	406	P05156
ESERQIRYLNHQLVI	CEP152	261	O94986
EAYERTHLQLRSELD	CEP152	706	O94986
EIHEYRRQLQARTIE	INA	311	Q16352
ELSLQEYQRVHILRF	ARHGEF38	731	Q9NXL2
LSVLGTEELRQREHY	CFAP36	261	Q96G28
TVLSVDRIYNRDIIH	FAT4	4316	Q6V0I7
ASEEDLLVVHTRRYL	HDAC11	66	Q96DB2
RIIELLTEAYGEVHI	APBA3	541	O96018
NELITLELIHRYVEL	AP1S1	76	P61966
EREHVLRLYSENDRL	CCDC77	121	Q9BR77
LSRELSLYLEHQVRV	ABHD3	11	Q8WU67
RETEIYNTVLLRHDN	ACVRL1	241	P37023
NRATLAAIIEHLYRV	ARAP2	1236	Q8WZ64
ALHLYRALTEVRDVN	CELSR2	2461	Q9HCU4
YNVLLETLSRTEEIH	LRPAP1	186	P30533
RVIIHDNRITQRIYE	C5orf52	91	A6NGY3
LYVFVDIRIDTTHLL	DPH1	151	Q9BZG8
IVLIEGDLTENYRHL	BBS12	356	Q6ZW61
RLIHQSDIIDRVVYD	AGTPBP1	681	Q9UPW5
ERLDRENISEYHLTA	CDH5	106	P33151
DREELDHYILQVVAS	CDH23	1486	Q9H251
HIREEIPLRSNVYEV	CDH23	2621	Q9H251
EQQRLYRLTVLVIDH	CDHR4	506	A6H8M9
VINELFYTERAHVRT	ARHGEF12	791	Q9NZN5
RLLRSHSEVQYVVLQ	AP3B2	346	Q13367
VEYIRALQRLLAEHD	ASCL2	96	Q99929
AHRQLVEVVRERYLS	NWD1	656	Q149M9
YEALRREHDSQIVQI	RC3H1	276	Q5TC82
IILTYDVNHRQSLVE	RAB20	76	Q9NX57
LEVLINLYRTHIDII	RBM43	321	Q6ZSC3
DYEQLRELQLRVTAH	PCDHGA7	521	Q9Y5G6
EHVQELESYIDRLLV	RAB11FIP5	621	Q9BXF6
RLFLEEHIRNITAIV	FAM81A	76	Q8TBF8
HISSLFREDQIYRID	G6PD	186	P11413
YSRNLEHLVEERTQL	GUCY2C	771	P25092
RYIHRDLATRNILVE	JAK2	971	O60674
IIHRDNIISDYDQII	GDAP1L1	101	Q96MZ0
RHEQITRAELRLYVS	GDF2	141	Q9UK05
VYVERIIVRLHETLF	LTN1	791	O94822
QERIEERLAYIADHL	ANK2	3566	Q01484
ELITLEIIHRYVELL	AP1S2	76	P56377
NELLTLEIVHRYVEL	AP1S3	76	Q96PC3
AVLVLEEYEHAVQRR	OXSM	281	Q9NWU1
LTHRTLDREEVSEYN	PCDHGA4	436	Q9Y5G9
IHDIQIVSTTRELYL	NUP210	116	Q8TEM1
DREEQAVYHLLVRAT	FAT1	3086	Q14517
YEAVSPERLELERQH	MAML1	41	Q92585
YNSDEIRPRTLLIEH	EFCAB2	111	Q5VUJ9
RHLDTEVNEVYISLL	HSPB2	151	Q16082
HRELYLRVELSDVQN	HACD3	16	Q9P035
QERDCHDVYISLIRL	MTMR7	86	Q9Y216
HITLDNRAEYVRLAI	HERC2	4621	O95714
LVAFRIVHDLISRDY	MMS19	191	Q96T76
YLTIRDVSLSHEVRE	MTO1	641	Q9Y2Z2
EAILQRLDHLEEVVY	GALNT9	61	Q9HCQ5
RLYEEEIRVLQSHIS	KRT86	241	O43790
TRYLRTVENLSVEHR	ESPN	321	B1AK53
TISDVLEIHRRVLGY	FICD	286	Q9BVA6
LHDQRVLVEPYVRVS	FER1L4	216	A9Z1Z3
LERVYSQRSRIHDEL	FAM89B	41	Q8N5H3
YRHLSDEEVLAFVVR	LMTK3	351	Q96Q04
TLHERQSAEYEALIR	CCDC88C	1176	Q9P219
HTDVVRYLLEQRADP	FEM1B	166	Q9UK73
YRLVIHRALDREQVS	PCDHGA10	406	Q9Y5H3
YHLTELDVVLFTRQI	MYLK3	606	Q32MK0
YRSVHRDLEAQIAIV	PGS1	491	Q32NB8
EASRVHLFDIITQYR	COG8	276	Q96MW5
TRDEYLSLVARLIIH	MED15	51	Q96RN5
HAQVLSYEVVELLRE	MPP4	86	Q96JB8
YEEELTQLRHELERQ	KRT23	336	Q9C075
IRSVYHLHQEEITRI	JAKMIP3	186	Q5VZ66
LRRLYEEEIRVLQSH	KRT87P	71	A6NCN2
DVTYAQLHSLTLRRE	LILRB5	551	O75023
HDENILESEPIVYRR	EDC3	246	Q96F86
ILEATQDDYVLEVRH	PTPRZ1	2171	P23471
RALYLEAIIQNHREV	RALGAPA2	1836	Q2PPJ7
YRLAEQHRQIEETLA	HK1	461	P19367
HELEDLEIRPRVSYV	OOSP4A	146	A0A2R8YFL7
TQHLRDLQVIAAYRE	NPHP4	946	O75161
VQTHIRALYLEPTED	SBF1	691	O95248
DEVHLTVAIVSYRTR	NOS1	1191	P29475
IISYDHSRVRLLVLD	PTPRT	921	O14522
LQVVYEHRSRLEKSL	GOLIM4	61	O00461
TLIAEDDRHYNIPVR	OTULIN	331	Q96BN8
RHLSIVDQDLEYLSE	OSGIN2	61	Q9Y236
LQRAILEESRQYHDI	B3GALT2	201	O43825
TEEVCRIYLLRILHT	EIF3C	496	Q99613
LILYETHRRVTLLAQ	WDPCP	361	O95876
NVQLIDEYIRDHSRT	EFCAB5	1431	A4FU69
TTEEVCRIYLLRILH	EIF3CL	496	B5ME19
RDLDELIVQHYTELT	EXOC4	56	Q96A65
DRYIIVVEHDLSVLD	ABCE1	266	P61221
LLDEESRIHATLLEY	CCDC93	191	Q567U6
VLAVNIYIERSREAH	CACNG8	221	Q8WXS5
LRYEERITELHSVIA	MCC	76	P23508
QHARRVYEILRLLVT	HAT1	326	O14929
NLEIRELERLYAHES	CCDC63	246	Q8NA47
RRIYDITNVLEGIHL	E2F3	216	O00716
HGSYVLRVEAERLTL	DOK1	171	Q99704
ENSHTLYDLDRIIEL	CRY2	146	Q49AN0
RDSVVEDLHLQNRYL	CEP290	2011	O15078
HVYTQQEVRELLGRL	FIG4	56	Q92562
HERILSEELVAAVTY	FIG4	386	Q92562
EIRRLQQHCTDLTYE	CCDC92	51	Q53HC0
IVEEYHDLYTLQRER	AXDND1	371	Q5T1B0
IVTREERRLTYVHNE	DPP8	241	Q6V1X1
YARSEAHLTELLEEI	CNPY2	71	Q9Y2B0
AIRVLVVERDHTYSQ	FOXRED1	91	Q96CU9
ILVRDEIALLHRYQS	CALHM4	171	Q5JW98
RYNDALLIHDTVRAV	DHX58	286	Q96C10
ESVRLHQINIYLSDR	GALNT12	96	Q8IXK2
LVSVELYEHLERFIV	DTHD1	466	Q6ZMT9
IEEILAIRAERYHLL	MCF2	131	P10911
VVAVRQELSHYRAVL	DBP	301	Q10586
LIITHREVQREYNLN	FAF1	196	Q9UNN5
SEILHRVIQELLVDY	HAUS4	81	Q9H6D7
LTLDFEYVINEVIRH	DCAF15	446	Q66K64
YEELHQRVLSLETRL	OLFM3	196	Q96PB7
EYEAHQDRVLIRLSR	RING1	116	Q06587
ASVVRSRNLLIYEEH	CREB3L2	421	Q70SY1
DLIRVVYSDLHPQRE	FAM126B	156	Q8IXS8
ETLYKEILTRAHERE	KLC1	401	Q07866
RLYEEEIRILQSHIS	KRT83	246	P78385
NVLVRVYVVRATDLH	OTOF	1491	Q9HC10
NIIAYDHSRVRLQTI	PTPRM	931	P28827
HLLEQYQTLREIRRA	PCGF6	311	Q9BYE7
VTYHLEDLRRRQSII	INCA1	116	Q0VD86
LTELYRDIFQHLRDE	NFE2	326	Q16621
LQEVYTLAEHRRTVA	IPO8	991	O15397
EIALLVRYLEEHTEF	MROH2A	621	A6NES4
RYTENSLRGVILDIH	FUT8	441	Q9BYC5
DVDLYQVRTARHNII	PSMD9	66	O00233
DRVEVYAHARSLIRE	SZT2	1926	Q5T011
VNIDIIHRIDRTASY	UTP20	26	O75691
QIEIERSLYSDHELR	MRPL46	76	Q9H2W6
LTEIIRHYQLLTEEN	STAT2	641	P52630
NEDRLIDRITLYQHL	SYNE1	6721	Q8NF91
LRELRLDNSVAIHYI	TMEM132D	281	Q14C87
RDIYSTVIDIHTLRI	TMEM200A	161	Q86VY9
YTSRIDEVLLHQDVD	GFOD1	51	Q9NXC2
YEVLSVREQLFHERI	LMBR1L	6	Q6UX01
DVTYAQLHSLTLRRE	LILRB1	611	Q8NHL6
TIEEFRAIYRIITHR	PLCZ1	56	Q86YW0
IITHREEIIEIFNTY	PLCZ1	66	Q86YW0
YEVEVHRLLSEAEVL	POMGNT1	541	Q8WZA1
YTESLLQLHDAEIVR	PRC1	326	O43663
RVRSLELYHQLVALV	SETD6	206	Q8TBK2
DVIHYVLDRRRTLNI	ST8SIA4	106	Q92187
EETRDLNYLLESHLR	SPATA31E1	131	Q6ZUB1
FRHAQDLILEIIYTE	PHYHIP	276	Q92561
RQRLIVCLEESLYIH	WIPI2	126	Q9Y4P8
IHRIDSTEVIYQPRR	STK11	26	Q15831
YVEDLRHQILAEEIR	STARD9	656	Q9P2P6
VHIYRLISERTVEEN	SRCAP	2161	Q6ZRS2
TRHNLEREEYTVLAD	TRIOBP	1261	Q9H2D6
EVSAVIIQRAYRRHL	SCN1A	1916	P35498
LVEQRRTLERYLEAH	TENT5B	316	Q96A09
DYRLTQIVVDHVIAE	SEMA3D	446	O95025
DREISQHIRIIYSST	C12orf56	96	Q8IXR9
YVVRVEHRVSSLQLL	TULP4	366	Q9NRJ4
THITEDICLDIIRRY	PLCL1	346	Q15111
LTQHYDRRSVRIEVT	ZNF532	631	Q9HCE3
ELLHYLLDAVRTEET	USP45	296	Q70EL2
RLVTDHLRLFTLYEQ	TEP1	1366	Q99973
HLRLFTLYEQVSERL	TEP1	1371	Q99973
RVPTLERHYEELQAR	SPTBN2	826	O15020
RVLQEYEVLRTLHHE	SPEG	3006	Q15772
ERSLEELLHYVGQLR	RMND5B	26	Q96G75
IRRIPIHNEDITYDE	TFG	21	Q92734
LYDRVDEEVHRLVLT	PLEKHG4B	436	Q96PX9
EVEIHRRYVAQSVQL	TMEM79	276	Q9BSE2
IDYTVHSVRRALENT	TPP2	471	P29144
YTIRLQIRHEQISDL	TPP2	886	P29144
QVAYVRARELHTLEV	nan	26	A6NDN8
AVEVTTLEELLRYLH	SEMA6C	761	Q9H3T2
HEAQLRRDTNVLVYI	ST7L	281	Q8TDW4
VLSLEEDVLRYHVVL	STAB2	1191	Q8WWQ8
YVVEEILELHIHRLR	PKD2L1	366	Q9P0L9
TVILEYAHRLSQDIL	C2orf88	56	Q9BSF0
QLSLRILDILEYIHE	VRK1	156	Q99986
HVLAELERQAVLVYT	ZC3H12D	151	A2A288
RLSLEFLAIEYREEH	TMEM262	101	E9PQX1
IIRVVFHDRRLQYTE	UBP1	116	Q9NZI7
SRHLITILDDIEVYE	UBE3B	536	Q7Z3V4
VLLVVQEQEYRTHRS	ZBTB7C	36	A1YPR0
LYVQLHGETTRRLEA	PHLPP1	471	O60346
TDVHLVERLQALYTI	USP18	156	Q9UMW8
VRHRILYLSEQLRVE	TEX28	51	O15482
TTYDHVTREKLDRIL	TRUB2	151	O95900
RSIHYISQVLLEEVE	VPS9D1	41	Q9Y2B5
VLQRLIHDRELSLYD	VWA8	526	A3KMH1
QLTAVRHREIQALYV	ZFYVE26	1641	Q68DK2
ALHLRYQTSQERVVD	USP6	1001	P35125
RHITYLEEELADFVL	TSC2	151	P49815
YTQILRERLRESIHN	DYNLT2	41	Q8IZS6
RERLRESIHNVQYVE	DYNLT2	46	Q8IZS6
RLYEEEILILQSHIS	KRT81	241	Q14533