Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	sodium:bicarbonate symporter activity	SLC4A7 SLC4A8 SLC4A10	8.01e-06	6	149	3	GO:0008510
GeneOntologyMolecularFunction	D-dopachrome decarboxylase activity	DDT DDTL	5.53e-05	2	149	2	GO:0033981
GeneOntologyMolecularFunction	monoatomic cation:bicarbonate symporter activity	SLC4A7 SLC4A8 SLC4A10	1.10e-04	13	149	3	GO:0140410
GeneOntologyMolecularFunction	phenylpyruvate tautomerase activity	DDT DDTL	1.65e-04	3	149	2	GO:0050178
GeneOntologyMolecularFunction	sodium,bicarbonate:chloride antiporter activity	SLC4A8 SLC4A10	1.65e-04	3	149	2	GO:0140892
GeneOntologyMolecularFunction	intramolecular oxidoreductase activity, interconverting keto- and enol-groups	DDT DDTL	3.29e-04	4	149	2	GO:0016862
GeneOntologyMolecularFunction	tubulin binding	DIP2B ARL8A KRIT1 GOLGA8N KIF7 ALMS1 ARL8B FMN1 DNM3 GOLGA8O TTLL13	3.77e-04	428	149	11	GO:0015631
GeneOntologyBiologicalProcess	homophilic cell adhesion via plasma membrane adhesion molecules	NRCAM PCDHGB5 PCDHGB1 CDHR1 AMIGO1 HMCN2 PTPRR DSG4 ROBO3	9.44e-06	187	150	9	GO:0007156
GeneOntologyBiologicalProcess	negative regulation of nodal receptor complex assembly	LEFTY2 LEFTY1	5.25e-05	2	150	2	GO:1900124
GeneOntologyBiologicalProcess	regulation of nodal receptor complex assembly	LEFTY2 LEFTY1	5.25e-05	2	150	2	GO:1900123
GeneOntologyBiologicalProcess	nodal receptor complex assembly	LEFTY2 LEFTY1	5.25e-05	2	150	2	GO:0038099
GeneOntologyBiologicalProcess	cell-cell adhesion via plasma-membrane adhesion molecules	NRCAM PCDHGB5 PCDHGB1 CDHR1 AMIGO1 TENM4 HMCN2 PTPRR DSG4 ROBO3	1.01e-04	313	150	10	GO:0098742
GeneOntologyBiologicalProcess	cell morphogenesis involved in neuron differentiation	DIP2B NRCAM CDHR1 DOCK10 PIAS2 AMIGO1 GOLGA8N DIP2A ANOS1 HMCN2 AFG3L2 DNM3 PAX6 ROBO3 GOLGA8O PLXNB1	1.14e-04	748	150	16	GO:0048667
GeneOntologyBiologicalProcess	neuron development	CDKN1C DIP2B SLC4A7 ERCC6 NRCAM CDHR1 DOCK10 PIAS2 AMIGO1 GOLGA8N DIP2A ANOS1 TENM4 HMCN2 ALMS1 TRIM32 AFG3L2 UHMK1 SLC4A10 DNM3 PAX6 ROBO3 GOLGA8O PLXNB1	1.44e-04	1463	150	24	GO:0048666
GeneOntologyCellularComponent	spindle	ARL8A HNRNPU GOLGA8N UNC119 ALMS1 ARL8B CEP95 SPIN1 BUB1B PKHD1 MICAL3 CKAP2 GOLGA8O	3.64e-05	471	150	13	GO:0005819
GeneOntologyCellularComponent	Golgi cis cisterna	GOLGA8R GOLGA8Q GOLGA8N GOLGA8O	8.86e-05	33	150	4	GO:0000137
GeneOntologyCellularComponent	spindle midzone	ARL8A HNRNPU UNC119 ARL8B	1.90e-04	40	150	4	GO:0051233
GeneOntologyCellularComponent	cis-Golgi network	GOLGA8R BCL9 GOLGA8Q GOLGA8N GOLGA8O	3.68e-04	85	150	5	GO:0005801
MousePheno	corneal-lenticular stalk	COL4A2 PXDN PAX6	2.58e-06	4	122	3	MP:0010713
MousePheno	hearing/vestibular/ear phenotype	COL4A2 RELCH COL9A2 ZEB1 SLC4A7 ERCC6 TCOF1 APAF1 MUC5B KRIT1 FREM2 ALMS1 KCNA10 CSNK1G3 SLC4A10 TBX10 ZFYVE26 HMGXB3 MICAL3 GJC3 PAX6	3.38e-05	905	122	21	MP:0005377
MousePheno	abnormal lens epithelium morphology	CDKN1C COL4A2 PXDN PAX6	4.30e-05	23	122	4	MP:0003237
MousePheno	abnormal left renal vein morphology	LEFTY2 LEFTY1	7.55e-05	2	122	2	MP:0011327
MousePheno	abnormal renal vein morphology	LEFTY2 LEFTY1	7.55e-05	2	122	2	MP:0011323
MousePheno	abnormal eye development	CDKN1C COL4A2 DNAJB11 ZEB1 TCOF1 APAF1 KRIT1 FREM2 GJA8 PXDN SPIN1 TBX10 HMGXB3 PAX6	7.86e-05	482	122	14	MP:0001286
MousePheno	iris hypoplasia	FREM2 PXDN PAX6	1.02e-04	11	122	3	MP:0006226
Domain	ANION_EXCHANGER_2	SLC4A7 SLC4A8 SLC4A10	1.67e-05	7	148	3	PS00220
Domain	ANION_EXCHANGER_1	SLC4A7 SLC4A8 SLC4A10	1.67e-05	7	148	3	PS00219
Domain	-	SLC4A7 SLC4A8 SLC4A10	3.96e-05	9	148	3	3.40.1100.10
Domain	Band3_cytoplasmic_dom	SLC4A7 SLC4A8 SLC4A10	3.96e-05	9	148	3	IPR013769
Domain	Band_3_cyto	SLC4A7 SLC4A8 SLC4A10	3.96e-05	9	148	3	PF07565
Domain	PTrfase/Anion_transptr	SLC4A7 SLC4A8 SLC4A10	5.62e-05	10	148	3	IPR016152
Domain	HCO3_transpt_euk	SLC4A7 SLC4A8 SLC4A10	5.62e-05	10	148	3	IPR003020
Domain	HCO3_cotransp	SLC4A7 SLC4A8 SLC4A10	5.62e-05	10	148	3	PF00955
Domain	HCO3_transpt_C	SLC4A7 SLC4A8 SLC4A10	5.62e-05	10	148	3	IPR011531
Domain	LRDF	LEFTY2 LEFTY1	6.24e-05	2	148	2	IPR003942
Domain	ATPase_dyneun-rel_AAA	VWA8 MDN1 DNAH8	1.66e-04	14	148	3	IPR011704
Domain	AAA_5	VWA8 MDN1 DNAH8	1.66e-04	14	148	3	PF07728
Domain	Macrophage_inhib_fac	DDT DDTL	1.86e-04	3	148	2	PD004816
Domain	Macrophage_inhib_fac_CS	DDT DDTL	1.86e-04	3	148	2	IPR019829
Domain	Tautomerase/MIF_sf	DDT DDTL	1.86e-04	3	148	2	IPR014347
Domain	MIF	DDT DDTL	1.86e-04	3	148	2	PS01158
Domain	Macrophage_inhib_fac	DDT DDTL	1.86e-04	3	148	2	IPR001398
Domain	MIF	DDT DDTL	1.86e-04	3	148	2	PF01187
Domain	-	ERCC6 VWA8 APAF1 MCM4 RHOT2 ARL8A SRCAP HNRNPU TRANK1 MDN1 ARL8B AFG3L2 DNM3 DNAH8 NLRP4 NLRP8	2.88e-04	746	148	16	3.40.50.300
Domain	Cadherin	PCDHGB5 PCDHGB1 CDHR1 FREM3 FREM2 DSG4	3.56e-04	118	148	6	IPR002126
Domain	GOLGA2L5	GOLGA8R GOLGA8N GOLGA8O	3.65e-04	18	148	3	PF15070
Domain	Golgin_A	GOLGA8R GOLGA8N GOLGA8O	3.65e-04	18	148	3	IPR024858
Domain	P-loop_NTPase	ERCC6 VWA8 APAF1 MCM4 RHOT2 ARL8A SRCAP HNRNPU KIF7 TRANK1 MDN1 ARL8B AFG3L2 DNM3 DNAH8 NLRP4 NLRP8	4.04e-04	848	148	17	IPR027417
Domain	FERM_M	FRMD8 FRMD4B KRIT1 FRMPD3	4.77e-04	46	148	4	PF00373
Domain	FERM_central	FRMD8 FRMD4B KRIT1 FRMPD3	6.08e-04	49	148	4	IPR019748
Domain	FERM_domain	FRMD8 FRMD4B KRIT1 FRMPD3	6.08e-04	49	148	4	IPR000299
Domain	Na/HCO3_transpt	SLC4A8 SLC4A10	6.14e-04	5	148	2	IPR003024
Domain	Anion_exchange	SLC4A7 SLC4A10	6.14e-04	5	148	2	IPR001717
Domain	DMAP_binding	DIP2B DIP2A	6.14e-04	5	148	2	PF06464
Domain	FERM_1	FRMD8 FRMD4B KRIT1 FRMPD3	6.57e-04	50	148	4	PS00660
Domain	FERM_2	FRMD8 FRMD4B KRIT1 FRMPD3	6.57e-04	50	148	4	PS00661
Domain	FERM_3	FRMD8 FRMD4B KRIT1 FRMPD3	6.57e-04	50	148	4	PS50057
Domain	Band_41_domain	FRMD8 FRMD4B KRIT1 FRMPD3	6.57e-04	50	148	4	IPR019749
Domain	B41	FRMD8 FRMD4B KRIT1 FRMPD3	6.57e-04	50	148	4	SM00295
Domain	DMAP1-bd	DIP2B DIP2A	9.16e-04	6	148	2	IPR010506
Domain	DMAP_binding	DIP2B DIP2A	9.16e-04	6	148	2	SM01137
Domain	Plectin	EPPK1 PPL	1.28e-03	7	148	2	PF00681
Domain	Plectin_repeat	EPPK1 PPL	1.28e-03	7	148	2	IPR001101
Domain	PLEC	EPPK1 PPL	1.28e-03	7	148	2	SM00250
Domain	AMP-binding	DIP2B ACSM1 DIP2A	1.69e-03	30	148	3	PF00501
Domain	AMP-dep_Synth/Lig	DIP2B ACSM1 DIP2A	1.69e-03	30	148	3	IPR000873
Domain	Calx_beta	FREM3 FREM2	1.69e-03	8	148	2	SM00237
Domain	K_chnl_volt-dep_Kv1	KCNA4 KCNA10	1.69e-03	8	148	2	IPR003972
Domain	Calx_beta	FREM3 FREM2	2.16e-03	9	148	2	IPR003644
Domain	Calx-beta	FREM3 FREM2	2.16e-03	9	148	2	PF03160
Domain	CA	PCDHGB5 PCDHGB1 CDHR1 FREM2 DSG4	2.23e-03	115	148	5	SM00112
Pathway	REACTOME_BICARBONATE_TRANSPORTERS	SLC4A7 SLC4A8 SLC4A10	4.64e-05	10	105	3	M27335
Pathway	REACTOME_BICARBONATE_TRANSPORTERS	SLC4A7 SLC4A8 SLC4A10	4.64e-05	10	105	3	MM15073
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	A2M DIP2B ARHGAP23 DOCK10 TBC1D17 HNRNPU FREM2 DIP2A TRIM32 WDR6 AFG3L2 NEMF BUB1B MICAL3 TIMELESS PLXNB1	3.99e-08	650	155	16	38777146
Pubmed	Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.	COL4A2 ARHGAP23 RBM33 ADAM23 PUF60 FAAP24 ACSM1 DERL2 TACC2 BCL9 FREM2 ANOS1 TRANK1 PXDN CSNK1G3 FER1L4 MICAL3 ROBO3 ATP1B3 C1orf94 PHF21B	1.19e-07	1215	155	21	15146197
Pubmed	Immunocytochemical identification of electroneutral Na⁺-coupled HCO₃⁻ transporters in freshly dissociated mouse medullary raphé neurons.	SLC4A7 SLC4A8 SLC4A10	8.63e-07	5	155	3	23500099
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	EPPK1 VWA8 PUF60 CUL9 FRMD8 RHOT2 BCL9 SRCAP SPPL2B TBC1D17 UNC119 DIP2A MDN1 CD2BP2 EIF4G1 ZFYVE26 HMGXB3 MICAL3	2.35e-06	1105	155	18	35748872
Pubmed	RNF12 catalyzes BRF1 ubiquitination and regulates RNA polymerase III-dependent transcription.	A2M SERBP1 TRIM27 HNRNPU PXDN	2.97e-06	50	155	5	30413534
Pubmed	A comparison of the dominant cataract and recessive specific-locus mutation rates induced by treatment of male mice with ethylnitrosourea.	COL4A2 GJA8 PAX6	3.00e-06	7	155	3	6877261
Pubmed	Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.	EPPK1 PUF60 DOCK10 PPL CEP95 AFG3L2 PKHD1 DOP1A	4.64e-06	208	155	8	33230847
Pubmed	Dual function of Yap in the regulation of lens progenitor cells and cellular polarity.	CDKN1C GOLGA8N PAX6 GOLGA8O	5.26e-06	26	155	4	24384391
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	DIP2B ZEB1 SLC4A8 NRCAM TCOF1 BCL9 PLA2G15 HNRNPU GOLGA8N KIF7 KCNA4 MDN1 EIF4G1 DNM3 FRMPD3 GOLGA8O	6.94e-06	963	155	16	28671696
Pubmed	JAM-C Is Important for Lens Epithelial Cell Proliferation and Lens Fiber Maturation in Murine Lens Development.	CDKN1C GJA8 PAX6	7.15e-06	9	155	3	38095908
Pubmed	Left-right asymmetry and kinesin superfamily protein KIF3A: new insights in determination of laterality and mesoderm induction by kif3A-/- mice analysis.	LEFTY2 LEFTY1 PAX6	7.15e-06	9	155	3	10330409
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	SLC4A7 FANCD2OS TACC2 RHOT2 SRCAP SPPL2B PLA2G15 PTPRR AOPEP FMN1 SPIN1 CSNK1G3 HMGXB3 TIMELESS CKAP2 NLRP4 PLXNB1	7.51e-06	1084	155	17	11544199
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	NRCAM SRCAP TRANK1 MDN1 ALMS1 ZFYVE26	7.53e-06	104	155	6	9205841
Pubmed	MicroRNA-127 Promotes Mesendoderm Differentiation of Mouse Embryonic Stem Cells by Targeting Left-Right Determination Factor 2.	LEFTY2 LEFTY1 PAX6	1.02e-05	10	155	3	27072135
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	DNAJB11 ERCC6 ARHGAP23 TCOF1 VWA8 TAF1C KIAA1549 CUL9 RHOT2 SRCAP TRIM27 KIF7 HMCN2 ALMS1 WDR6 AFG3L2 TRAF3IP3	1.09e-05	1116	155	17	31753913
Pubmed	The Catalytically Inactive Mutation of the Ubiquitin-Conjugating Enzyme CDC34 Affects its Stability and Cell Proliferation.	DIP2B MCM4 RHOT2 ARL8A MDN1 ARL8B WDR6 AFG3L2	1.20e-05	237	155	8	29564676
Pubmed	Hippi is essential for node cilia assembly and Sonic hedgehog signaling.	LEFTY2 LEFTY1 PAX6	1.40e-05	11	155	3	17027958
Pubmed	Drosophila Topors is a RING finger-containing protein that functions as a ubiquitin-protein isopeptide ligase for the hairy basic helix-loop-helix repressor protein.	ARL8A ARL8B	1.97e-05	2	155	2	14871887
Pubmed	LEFTY2 alleviates hepatic stellate cell activation and liver fibrosis by regulating the TGF-β1/Smad3 pathway.	LEFTY2 LEFTY1	1.97e-05	2	155	2	32745796
Pubmed	K+-Driven Cl-/HCO3- Exchange Mediated by Slc4a8 and Slc4a10.	SLC4A8 SLC4A10	1.97e-05	2	155	2	38674160
Pubmed	LEFTY, a member of the transforming growth factor-beta superfamily, inhibits uterine stromal cell differentiation: a novel autocrine role.	LEFTY2 LEFTY1	1.97e-05	2	155	2	20056823
Pubmed	Characterization and mutation analysis of human LEFTY A and LEFTY B, homologues of murine genes implicated in left-right axis development.	LEFTY2 LEFTY1	1.97e-05	2	155	2	10053005
Pubmed	Mutation analysis of human LEFTY A and LEFTY B genes in children with Ivemark syndrome.	LEFTY2 LEFTY1	1.97e-05	2	155	2	11100524
Pubmed	Inhibition of bone morphogenetic protein 1 by native and altered forms of alpha2-macroglobulin.	A2M BMP1	1.97e-05	2	155	2	17071617
Pubmed	An N-terminally acetylated Arf-like GTPase is localised to lysosomes and affects their motility.	ARL8A ARL8B	1.97e-05	2	155	2	16537643
Pubmed	Lefty1 and lefty2 control the balance between self-renewal and pluripotent differentiation of mouse embryonic stem cells.	LEFTY2 LEFTY1	1.97e-05	2	155	2	24147624
Pubmed	Presynaptic Biogenesis Requires Axonal Transport of Lysosome-Related Vesicles.	ARL8A ARL8B	1.97e-05	2	155	2	30174114
Pubmed	Intracorneal positioning of the lens in Pax6-GAL4/VP16 transgenic mice.	CDKN1C PAX6	1.97e-05	2	155	2	16270027
Pubmed	Loss of circadian gene Timeless induces EMT and tumor progression in colorectal cancer via Zeb1-dependent mechanism.	ZEB1 TIMELESS	1.97e-05	2	155	2	35034102
Pubmed	Cloning of the mouse gene for D-dopachrome tautomerase.	DDT DDTL	1.97e-05	2	155	2	9858785
Pubmed	Distribution maps of D-dopachrome tautomerase in the mouse brain.	DDT DDTL	1.97e-05	2	155	2	23000624
Pubmed	Lefty antagonises TGF-beta1 induced epithelial-mesenchymal transition in tubular epithelial cells.	LEFTY2 LEFTY1	1.97e-05	2	155	2	20171171
Pubmed	Stra3/lefty, a retinoic acid-inducible novel member of the transforming growth factor-beta superfamily.	LEFTY2 LEFTY1	1.97e-05	2	155	2	9496783
Pubmed	A functional role of LEFTY during progesterone therapy for endometrial carcinoma.	LEFTY2 LEFTY1	1.97e-05	2	155	2	29268772
Pubmed	Lefty1 Ameliorates Post-infarction Fibrosis by Suppressing p-Smad2 and p-ERK1/2 Signaling Pathways.	LEFTY2 LEFTY1	1.97e-05	2	155	2	33409963
Pubmed	LEFTY2 inhibits endometrial receptivity by downregulating Orai1 expression and store-operated Ca2+ entry.	LEFTY2 LEFTY1	1.97e-05	2	155	2	29230527
Pubmed	Molecular analysis of LEFTY-expressing cells in early human embryoid bodies.	LEFTY2 LEFTY1	1.97e-05	2	155	2	17038673
Pubmed	Anti-inflammatory effects of Lefty-1 in renal tubulointerstitial inflammation via regulation of the NF-κB pathway.	LEFTY2 LEFTY1	1.97e-05	2	155	2	29286065
Pubmed	Chronic continuous hypoxia decreases the expression of SLC4A7 (NBCn1) and SLC4A10 (NCBE) in mouse brain.	SLC4A7 SLC4A10	1.97e-05	2	155	2	17928512
Pubmed	Isolation, characterization, and function of EBAF/LEFTY B: role in infertility.	LEFTY2 LEFTY1	1.97e-05	2	155	2	21401636
Pubmed	Lefty is expressed in mouse endometrium in estrous cycle and peri-implantation period.	LEFTY2 LEFTY1	1.97e-05	2	155	2	15640253
Pubmed	Ftm is a novel basal body protein of cilia involved in Shh signalling.	LEFTY2 LEFTY1 PAX6	2.40e-05	13	155	3	17553904
Pubmed	Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST.	NRCAM DOCK10 CSNK1G3 SLC4A10 DNM3 DOP1A	2.46e-05	128	155	6	30995482
Pubmed	Mechanism for generation of left isomerism in Ccdc40 mutant embryos.	LEFTY2 LEFTY1 PAX6	3.05e-05	14	155	3	28182636
Pubmed	Cell cycle arrest in node cells governs ciliogenesis at the node to break left-right symmetry.	CDKN1C LEFTY2 LEFTY1	3.80e-05	15	155	3	21831921
Pubmed	Mouse homologues of Shisa antagonistic to Wnt and Fgf signalings.	LEFTY2 LEFTY1 PAX6	3.80e-05	15	155	3	17481602
Pubmed	GM130 Regulates Golgi-Derived Spindle Assembly by Activating TPX2 and Capturing Microtubules.	BCL9 GOLGA8N GOLGA8O	3.80e-05	15	155	3	26165940
Pubmed	Selective inactivation of Otx2 mRNA isoforms reveals isoform-specific requirement for visceral endoderm anteriorization and head morphogenesis and highlights cell diversity in the visceral endoderm.	LEFTY2 LEFTY1 PAX6	3.80e-05	15	155	3	19615442
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	VWA8 PI4K2A MCM4 TRIM32 WDR6 CD2BP2 AFG3L2 EIF4G1 TIMELESS CKAP2 SNTB2	4.59e-05	560	155	11	35241646
Pubmed	Rotatin is a novel gene required for axial rotation and left-right specification in mouse embryos.	LEFTY2 LEFTY1 PAX6	4.66e-05	16	155	3	11900971
Pubmed	Identification of a novel cell-adhesive protein spatiotemporally expressed in the basement membrane of mouse developing hair follicle.	COL4A2 FREM3 FREM2	4.66e-05	16	155	3	15878328
Pubmed	Charting the landscape of tandem BRCT domain-mediated protein interactions.	DNAJB11 SERBP1 TCOF1 PUF60 MCM4 PIAS2 UNC119 ALMS1 WDR6 CD2BP2 MICAL3 ATP1B3	5.03e-05	670	155	12	22990118
Pubmed	Synergistic gene interactions control the induction of the mitochondrial uncoupling protein (Ucp1) gene in white fat tissue.	GJA8 KCNA4 KCNA10	5.64e-05	17	155	3	10931824
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	A2M DIP2B DNAJB11 ARHGAP23 ACAD10 KRIT1 TENM4 WDR6 FMN1 NEMF	5.78e-05	475	155	10	31040226
Pubmed	Mouse models for hereditary spastic paraplegia uncover a role of PI4K2A in autophagic lysosome reformation.	PI4K2A ZFYVE26	5.90e-05	3	155	2	33618608
Pubmed	Nodal and lefty signaling regulates the growth of pancreatic cells.	LEFTY2 LEFTY1	5.90e-05	3	155	2	18393305
Pubmed	Lefty-1 inhibits renal epithelial-mesenchymal transition by antagonizing the TGF-β/Smad signaling pathway.	LEFTY2 LEFTY1	5.90e-05	3	155	2	32065356
Pubmed	"Near Cure" treatment of severe acute EAE in MIF-1-deficient female and male mice with a bifunctional MHCII-derived molecular construct.	DDT DDTL	5.90e-05	3	155	2	35738135
Pubmed	Role of asymmetric signals in left-right patterning in the mouse.	LEFTY2 LEFTY1	5.90e-05	3	155	2	11471154
Pubmed	Decidual differentiation of stromal cells promotes Proprotein Convertase 5/6 expression and lefty processing.	LEFTY2 LEFTY1	5.90e-05	3	155	2	16141390
Pubmed	Conserved gene structure and genomic linkage for D-dopachrome tautomerase (DDT) and MIF.	DDT DDTL	5.90e-05	3	155	2	9716662
Pubmed	IFT46 plays an essential role in cilia development.	LEFTY2 LEFTY1	5.90e-05	3	155	2	25722189
Pubmed	Distinct transcriptional regulation and phylogenetic divergence of human LEFTY genes.	LEFTY2 LEFTY1	5.90e-05	3	155	2	10886363
Pubmed	Regulation of the human NBC3 Na+/HCO3- cotransporter by carbonic anhydrase II and PKA.	SLC4A7 SLC4A8	5.90e-05	3	155	2	14736710
Pubmed	Association of maternal hypertension and diabetes with variants of the NKX2-5, LEFTY1 and LEFTY2 genes in children with congenital heart defects: a case-control study from Pakistani Population.	LEFTY2 LEFTY1	5.90e-05	3	155	2	37097539
Pubmed	CGG-repeat expansion in the DIP2B gene is associated with the fragile site FRA12A on chromosome 12q13.1.	DIP2B DIP2A	5.90e-05	3	155	2	17236128
Pubmed	Lefty-1 alleviates TGF-β1-induced fibroblast-myofibroblast transdifferentiation in NRK-49F cells.	LEFTY2 LEFTY1	5.90e-05	3	155	2	26316705
Pubmed	Genetic regulation of gene expression of MIF family members in lung tissue.	DDT DDTL	5.90e-05	3	155	2	33046825
Pubmed	Macrophage migration inhibitory factor (MIF) and its homolog D-dopachrome tautomerase (D-DT) are significant promotors of UVB- but not chemically induced non-melanoma skin cancer.	DDT DDTL	5.90e-05	3	155	2	37464010
Pubmed	Lefty inhibits in vitro decidualization by regulating P57 and cyclin D1 expressions.	CDKN1C LEFTY1	5.90e-05	3	155	2	25339094
Pubmed	Generation of robust left-right asymmetry in the mouse embryo requires a self-enhancement and lateral-inhibition system.	LEFTY2 LEFTY1	5.90e-05	3	155	2	17011489
Pubmed	Plakins: a family of versatile cytolinker proteins.	EPPK1 PPL	5.90e-05	3	155	2	11854008
Pubmed	Targeting distinct tautomerase sites of D-DT and MIF with a single molecule for inhibition of neutrophil lung recruitment.	DDT DDTL	5.90e-05	3	155	2	25016026
Pubmed	Novel Helicobacter species H.japonicum isolated from laboratory mice from Japan induces typhlocolitis and lower bowel carcinoma in C57BL/129 IL10-/- mice.	LEFTY2 LEFTY1	5.90e-05	3	155	2	27655833
Pubmed	Embryonic asymmetry: the left side gets all the best genes.	LEFTY2 LEFTY1	5.90e-05	3	155	2	9889116
Pubmed	Two modes by which Lefty proteins inhibit nodal signaling.	LEFTY2 LEFTY1	5.90e-05	3	155	2	15062104
Pubmed	Requirements of LEFTY and Nodal overexpression for tumor cell survival under hypoxia in glioblastoma.	LEFTY2 LEFTY1	5.90e-05	3	155	2	33111989
Pubmed	DMH1, a highly selective small molecule BMP inhibitor promotes neurogenesis of hiPSCs: comparison of PAX6 and SOX1 expression during neural induction.	BMP1 PAX6	5.90e-05	3	155	2	22860217
Pubmed	Lefty1 alleviates renal tubulointerstitial injury in mice with unilateral ureteral obstruction.	LEFTY2 LEFTY1	5.90e-05	3	155	2	26647776
Pubmed	TGFβ signaling in establishing left-right asymmetry.	LEFTY2 LEFTY1	5.90e-05	3	155	2	24704359
Pubmed	The COOH termini of NBC3 and the 56-kDa H+-ATPase subunit are PDZ motifs involved in their interaction.	SLC4A7 SLC4A8	5.90e-05	3	155	2	12444018
Pubmed	Randomization of left-right asymmetry due to loss of nodal cilia generating leftward flow of extraembryonic fluid in mice lacking KIF3B motor protein.	LEFTY2 LEFTY1	5.90e-05	3	155	2	9865700
Pubmed	Nodal activates smad and extracellular signal-regulated kinases 1/2 pathways promoting renal cell carcinoma proliferation.	LEFTY2 LEFTY1	5.90e-05	3	155	2	25672326
Pubmed	Expression of Fraser syndrome genes in normal and polycystic murine kidneys.	FREM3 FREM2	5.90e-05	3	155	2	21993971
Pubmed	C2cd3 is required for cilia formation and Hedgehog signaling in mouse.	LEFTY2 LEFTY1 PAX6	6.74e-05	18	155	3	19004860
Pubmed	Disruption of a ciliary B9 protein complex causes Meckel syndrome.	LEFTY2 LEFTY1 PAX6	6.74e-05	18	155	3	21763481
Pubmed	LncCMRR Plays an Important Role in Cardiac Differentiation by Regulating the Purb/Flk1 Axis.	LEFTY2 LEFTY1 PAX6	6.74e-05	18	155	3	36318802
Pubmed	SDF2L1 interacts with the ER-associated degradation machinery and retards the degradation of mutant proinsulin in pancreatic β-cells.	DERL2 GOLGA8N GOLGA8O	7.98e-05	19	155	3	23444373
Pubmed	Loss of Glis3 causes dysregulation of retrotransposon silencing and germ cell demise in fetal mouse testis.	LEFTY2 LEFTY1 BOLL	7.98e-05	19	155	3	29941866
Pubmed	Accelerating functional gene discovery in osteoarthritis.	COL4A2 RBM33 HMGXB3 TIMELESS	9.37e-05	53	155	4	33473114
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	DIP2B DNAJB11 TCOF1 VWA8 PUF60 SRCAP ZC3H6 HNRNPU TRIM32 SPIN1 CD2BP2 NEMF EIF4G1 DNM3 PLXNB1	1.06e-04	1082	155	15	38697112
Pubmed	EIF3H Orchestrates Hippo Pathway-Mediated Oncogenesis via Catalytic Control of YAP Stability.	SERBP1 PUF60 HNRNPU EIF4G1	1.08e-04	55	155	4	32269044
Pubmed	Dynamics of the rhomboid-like protein RHBDD2 expression in mouse retina and involvement of its human ortholog in retinitis pigmentosa.	BCL9 GOLGA8N GOLGA8O	1.09e-04	21	155	3	23386608
Pubmed	Planar cell polarity breaks bilateral symmetry by controlling ciliary positioning.	LEFTY2 LEFTY1 PAX6	1.09e-04	21	155	3	20562861
Pubmed	A mutation in the pericentrin gene causes abnormal interneuron migration to the olfactory bulb in mice.	DDT DIP2A PAX6 DDTL	1.16e-04	56	155	4	20096683
Pubmed	Asymmetric Nodal expression in the mouse is governed by the combinatorial activities of two distinct regulatory elements.	LEFTY2 LEFTY1	1.18e-04	4	155	2	15454269
Pubmed	Exome sequencing in developmental eye disease leads to identification of causal variants in GJA8, CRYGC, PAX6 and CYP1B1.	GJA8 PAX6	1.18e-04	4	155	2	24281366
Pubmed	The dynamic right-to-left translocation of Cerl2 is involved in the regulation and termination of Nodal activity in the mouse node.	LEFTY2 LEFTY1	1.18e-04	4	155	2	23544137
Pubmed	A SCL4A10 gene product maps selectively to the basolateral plasma membrane of choroid plexus epithelial cells.	SLC4A7 SLC4A10	1.18e-04	4	155	2	14592810
Pubmed	Cooperative regulation of non-small cell lung carcinoma angiogenic potential by macrophage migration inhibitory factor and its homolog, D-dopachrome tautomerase.	DDT DDTL	1.18e-04	4	155	2	18684922
Cytoband	Ensembl 112 genes in cytogenetic band chr15q13	GOLGA8R GOLGA8Q GOLGA8N FMN1 GOLGA8O	2.39e-05	100	155	5	chr15q13
GeneFamily	Ankyrin repeat domain containing\|FERM domain containing	FRMD8 FRMD4B KRIT1 FRMPD3	1.67e-04	50	100	4	1293
GeneFamily	EF-hand domain containing\|Plakins	EPPK1 PPL	8.30e-04	8	100	2	939
GeneFamily	PDZ domain containing	LNX2 ARHGAP23 FRMPD2B FRMPD3 SNTB2	1.56e-03	152	100	5	1220
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	NRCAM PXDN HMCN2 ROBO3 ALPK2	2.01e-03	161	100	5	593
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	A2M NRCAM MUC5B FREM2 TRANK1 TENM4 KCNA4 DGKK PKHD1	1.77e-08	184	155	9	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	A2M NRCAM MUC5B FREM2 TRANK1 TENM4 KCNA4 DGKK PKHD1	1.77e-08	184	155	9	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	A2M NRCAM MUC5B FREM2 TRANK1 TENM4 KCNA4 DGKK PKHD1	1.77e-08	184	155	9	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated\|COVID-19_Mild / Disease, condition lineage and cell class	A2M GOLGA8R SRCAP GOLGA8Q DIP2A TRANK1 DGKK GOLGA8O	5.21e-07	200	155	8	2281debd86e5d92e8fe0397aec9ef670800f7471
ToppCell	tumor_Lymph_Node_/_Brain-Fibroblasts-Smooth_muscle_cells\|Fibroblasts / Location, Cell class and cell subclass	COL9A2 KIAA1549 NCF2 TACC2 LEFTY2 KCNA4 IL17RA	3.18e-06	179	155	7	83506e00fe99b6450efd2f13f716926a0a4b03cd
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC4A7 SLC4A8 NRCAM VWA8 TENM4 FMN1 PHF21B	4.09e-06	186	155	7	1850583d23903d08226aeb0edb3e07b0994330e4
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC4A7 SLC4A8 NRCAM VWA8 TENM4 FMN1 PHF21B	4.09e-06	186	155	7	4dafc215c42e7949f932a3627359c107943b5d6b
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Macroglial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LARP6 ARHGAP23 FRMD8 ARL8A LEFTY1 GJC3 ATP1B3	4.87e-06	191	155	7	d45b6aa64667d29ac043c3987902e7f7ddbcf940
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Macroglial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LARP6 ARHGAP23 FRMD8 ARL8A LEFTY1 GJC3 ATP1B3	5.04e-06	192	155	7	49a34b55788d7ca955936fff1c0501ed674a9f3c
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Macroglial-oligodendrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LARP6 ARHGAP23 FRMD8 ARL8A LEFTY1 GJC3 ATP1B3	5.22e-06	193	155	7	4274c95cedad2ae8c6693ad00deda2b1ba5b5682
ToppCell	COVID-19_Severe-Lymphoid_T/NK-gd_T\|COVID-19_Severe / Disease group, lineage and cell class	A2M RGS9 GOLGA8Q DIP2A DGKK UHMK1 GOLGA8O	5.58e-06	195	155	7	9990440bda7fac5d00ef80444fab07459be625e1
ToppCell	kidney_cells-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A2 BMP1 PXDN CEP95 PKHD1 ALPK2 PLXNB1	6.37e-06	199	155	7	174f6013af6eafa577f84205a62927f2b367fda3
ToppCell	COVID-19-COVID-19_Severe-Lymphocyte-T/NK-gd_T\|COVID-19_Severe / Disease, condition lineage and cell class	A2M RGS9 GOLGA8Q DIP2A DGKK UHMK1 GOLGA8O	6.59e-06	200	155	7	f72bc3f6606ae77fe1b0a972e35b3ce0727804d9
ToppCell	LPS-antiTNF-Epithelial_alveolar-Mes-like-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PIPOX FNDC4 ANKMY1 BCL9 BUB1B TNFSF15	1.06e-05	142	155	6	5690eee2ce1ecd02e34eac4193578bd13c4228b9
ToppCell	390C-Myeloid-Macrophage-SPP1+_Macrophage_3\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	VWA8 FNDC4 NCF2 PLA2G15 AMIGO1 ALPK2	1.39e-05	149	155	6	13b445c13bb8f31ff0876addd1baf969ae220ea3
ToppCell	Dendritic_Cells-IPF_03\|World / lung cells shred on cell class, cell subclass, sample id	ZEB1 TCOF1 ACSM1 DOCK10 TENM4 LILRA4	1.50e-05	151	155	6	e089bf197ed60e7243160521d4390d4b40a3832b
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Myeloid\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDHR1 FREM3 LIPM TRAF3IP3 C1orf94 ALPK2	1.87e-05	157	155	6	7fdc0094dd5729990a91a30c1982a14c74650b52
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Myeloid-microglial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDHR1 FREM3 LIPM TRAF3IP3 C1orf94 ALPK2	1.87e-05	157	155	6	c762b03e254c73222094725ca8ac1c8eb428bccb
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Myeloid-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDHR1 FREM3 LIPM TRAF3IP3 C1orf94 ALPK2	1.87e-05	157	155	6	6b5b08bb5520fcf6f4c0560f7ed7645ec179806d
ToppCell	367C-Fibroblasts-Fibroblast-G-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	A2M SLC4A8 KCNA4 FMN1 DDTL	2.27e-05	97	155	5	a1279377bf0ee5662db8b9303f5f1fd418dee6df
ToppCell	367C-Fibroblasts-Fibroblast-G\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	A2M SLC4A8 KCNA4 FMN1 DDTL	2.27e-05	97	155	5	12cbd03b33e76e5e471bbee2a9c11f27e8b21123
ToppCell	CV-Mild-7\|CV / Virus stimulation, Condition and Cluster	PIAS2 ZC3H6 BMP1 GSTCD ALPK2 DOP1A	2.92e-05	170	155	6	25ebde7d2f8ae1afdfaf5876284ff20bb179eb10
ToppCell	CV-Mild-7\|Mild / Virus stimulation, Condition and Cluster	PIAS2 ZC3H6 BMP1 GSTCD ALPK2 DOP1A	3.22e-05	173	155	6	c9bbca9313a0fdf146c8c995624b94b937e818d8
ToppCell	AT1_cells-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	COL4A2 FREM3 ANOS1 KCNA4 PTPRR PLXNB1	3.90e-05	179	155	6	1603117b52623663458a977c94bf7f9f6c1114b8
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	COL4A2 ZEB1 NRCAM TACC2 TENM4 PHF21B	4.28e-05	182	155	6	ed6ae0fd8653f213fe29906a6a4e0729a62e1b75
ToppCell	COVID-19-kidney-PCT-S1\|kidney / Disease (COVID-19 only), tissue and cell type	COL4A2 NRCAM KIAA1549 FRMD4B PKHD1 ALPK2	4.55e-05	184	155	6	51ed1ebfdef45149541917c66cbacad87072e51f
ToppCell	TCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-3\|TCGA-Lung / Sample_Type by Project: Shred V9	DIP2B NRCAM ADAM23 CDHR1 TENM4 EIF4G1	4.55e-05	184	155	6	ea4ccebe2d54279fcc517e4f0bfa652b91a808bb
ToppCell	COVID-19_Severe-gd_T\|COVID-19_Severe / Disease condition and Cell class	A2M CDHR1 RGS9 GOLGA8Q DIP2A GOLGA8O	4.55e-05	184	155	6	791f1bcb954aadc63d4117c400537d036f68734d
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC4A7 SLC4A8 NRCAM VWA8 TENM4 FMN1	4.69e-05	185	155	6	03f64a7132b13a01ba47187e0e15c13ac88f7cb2
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CDKN1C COL9A2 ARHGAP23 DOCK10 FRMD4B PLXNB1	4.97e-05	187	155	6	97e520705491c8f52a32025311a9fa7b9176979a
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CDKN1C COL9A2 DOCK10 FRMD4B TP53TG5 PLXNB1	5.28e-05	189	155	6	b60c8a29d3169c4830fe63b01db90c57660fc239
ToppCell	droplet-Heart-HEART-1m-Endothelial-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDKN1C COL4A2 LNX2 MYL3 PTPRR BOLL	5.28e-05	189	155	6	4225bbff4037eecc93a12abad3a38dd04b1e22be
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CDKN1C FREM2 ANOS1 FMN1 PKHD1 TNFSF15	5.43e-05	190	155	6	8aea807a2bcf0b653b4de6202b6ecb0f0683cc2e
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-A\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SLC4A7 RGS9 BCL9 SRCAP ZNF773 FMN1	5.43e-05	190	155	6	63018acb7ad80415e861643162abdc2e55968ee4
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW26-Stem_cells\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	DEPDC4 CDHR1 TP53TG5 BUB1B GDPGP1 TTLL13	5.93e-05	193	155	6	3091090abcf18b48eac7e6c85653c18aa54fcb9b
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW26-Stem_cells-Stem_cells\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	DEPDC4 CDHR1 TP53TG5 BUB1B GDPGP1 TTLL13	5.93e-05	193	155	6	a18770ceb770aaa4903dd04442ad0a73159ead9a
ToppCell	PCW_07-8.5\|World / Celltypes from embryonic and fetal-stage human lung	DNAJB11 TACC2 TENM4 BUB1B CKAP2 PHF21B	6.10e-05	194	155	6	5759c83308df017f1faae248e9b85388e25254f0
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CDKN1C LEFTY2 FREM2 ANOS1 HMCN2 ACOT2	6.27e-05	195	155	6	8a04f0e92d10a368ccda5f566ae67ef51f1d34a9
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	A2M RGS9 DIP2A DGKK UHMK1 GOLGA8O	6.45e-05	196	155	6	418e8e0a51c5cb60e3b903e7d2d800dc8b9f3d5c
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	A2M RGS9 DIP2A DGKK UHMK1 GOLGA8O	6.45e-05	196	155	6	6beaf0c2799424c59819b286fbb5c1a83d85e4d1
ToppCell	TCGA-Head_and_Esophagus-Primary_Tumor\|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9	COL4A2 MCM4 BMP1 BUB1B TIMELESS CKAP2	6.64e-05	197	155	6	1bb8f9535a9ab6c7a444bcbe346fcc0a13b09bdf
ToppCell	wk_15-18-Mesenchymal-Myofibro_&_SMC-MYL4+_SMC\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	CDKN1C ZEB1 LEFTY2 ANOS1 AOPEP ACOT2	6.64e-05	197	155	6	4797f414330316e2ac2cf7cd2570d991877d7a38
ToppCell	COVID_non-vent-Lymphocytic-ILC\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	GOLGA8R GOLGA8Q GOLGA8N DIP2A TRANK1 GOLGA8O	7.02e-05	199	155	6	df4f7d5be099e3e6054f3b812ccf70251664e4c0
ToppCell	COVID_vent-Lymphocytic-ILC\|COVID_vent / Disease condition, Lineage, Cell class and subclass	GOLGA8R GOLGA8Q GOLGA8N DIP2A DGKK GOLGA8O	7.02e-05	199	155	6	e3ff7fa1b1de1aaf6b46cdf49afa95bad457728a
ToppCell	COVID_non-vent-Lymphocytic-ILC-NK_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	GOLGA8R GOLGA8Q GOLGA8N DIP2A TRANK1 GOLGA8O	7.02e-05	199	155	6	ed35d747f11f6ea6a5cb7061057f0a98d9e0db99
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Macroglial-oligodendrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LARP6 ARHGAP23 DOCK10 FRMD8 DIP2A GJC3	7.02e-05	199	155	6	67d8c7e5356f5d409d4f98e8338cf6c499fd7aee
ToppCell	COVID_vent-Lymphocytic-ILC-NK_cell\|COVID_vent / Disease condition, Lineage, Cell class and subclass	GOLGA8R GOLGA8Q GOLGA8N DIP2A DGKK GOLGA8O	7.02e-05	199	155	6	5f914962e2572b0c6372465b81b7496fa663d93c
ToppCell	Macroglial-Oligodendrocytes\|Macroglial / cells hierarchy compared to all cells using T-Statistic	DIP2B LARP6 DOCK10 FRMD4B TP53TG5 FMN1	7.22e-05	200	155	6	4dbac2f2587e87ca5a0622f50439bb5447e93c7f
ToppCell	Parenchymal-NucSeq-Immune_Myeloid-Mast_cell\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SLC4A8 NRCAM DOCK10 KIAA1549 TRAF3IP3 ATP1B3	7.22e-05	200	155	6	9156f8fd61a833891d2f7b7fadd693b81b1e2d5a
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LARP6 ARHGAP23 DOCK10 FRMD8 DIP2A GJC3	7.22e-05	200	155	6	0e85c90719d9ec51a566e230c9dd2909d8df1f52
ToppCell	facs-Brain_Non-Myeloid-Hippocampus\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK10 FRMD8 HNRNPU DIP2A GJC3 ATP1B3	7.22e-05	200	155	6	fc28f71ca1cd0fdae66009ae5afe175d22f2bd8c
ToppCell	Parenchymal-NucSeq-Immune_Myeloid-Mast_cell-Mast_cell\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SLC4A8 NRCAM DOCK10 KIAA1549 TRAF3IP3 ATP1B3	7.22e-05	200	155	6	566fe2e78e6f35399ec6aad5964f6d4d8ade82c6
ToppCell	Macroglial-Oligodendrocytes-OPALIN--\|Macroglial / cells hierarchy compared to all cells using T-Statistic	DIP2B LARP6 DOCK10 FRMD4B TP53TG5 FMN1	7.22e-05	200	155	6	26b989e30bbbaf30904ced03f6aae3dea25c732c
ToppCell	Macroglial-Oligodendrocytes-OPALIN---\|Macroglial / cells hierarchy compared to all cells using T-Statistic	DIP2B LARP6 DOCK10 FRMD4B TP53TG5 FMN1	7.22e-05	200	155	6	1314664c1721e9ecb1e2c3482a039044b0fe50a9
ToppCell	Macroglial-Oligodendrocytes-OPALIN-\|Macroglial / cells hierarchy compared to all cells using T-Statistic	DIP2B LARP6 DOCK10 FRMD4B TP53TG5 FMN1	7.22e-05	200	155	6	8b229f095fc113aecfc94b64862a9e0fdcc363ce
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-oligodendrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LARP6 ARHGAP23 DOCK10 FRMD8 DIP2A GJC3	7.22e-05	200	155	6	e5b4821fff40566c4a7dc3f74a14e27eb06b165d
ToppCell	Macroglial-Oligodendrocytes-OPALIN----L1-6\|Macroglial / cells hierarchy compared to all cells using T-Statistic	DIP2B LARP6 DOCK10 FRMD4B TP53TG5 FMN1	7.22e-05	200	155	6	272909f4354f3ae22e2b2f8f35970e6b0e92cfe2
ToppCell	Macroglial-Oligodendrocytes-OPALIN\|Macroglial / cells hierarchy compared to all cells using T-Statistic	DIP2B LARP6 DOCK10 FRMD4B TP53TG5 FMN1	7.22e-05	200	155	6	5f75a9b8bcd49d9bbb1e9ce2de730eaec96369ca
ToppCell	E18.5-samps-Mesenchymal-Matrix_fibroblast-matrix_-_immature_4\|E18.5-samps / Age Group, Lineage, Cell class and subclass	ERCC6 TCOF1 BUB1B GSTCD CKAP2	9.21e-05	130	155	5	169d88bffd7cd813a484d809defa638ceaca4bcb
ToppCell	Control-Fibroblasts-Mesothelial_FB\|Control / group, cell type (main and fine annotations)	NRCAM RGS9 TENM4 ALPK2 PHF21B	1.26e-04	139	155	5	e769beb031b262dd92c9605b07dbf3c29fb82520
Drug	Rimexolone [49697-38-3]; Down 200; 10.8uM; PC3; HT_HG-U133A	FAAP24 PI4K2A MCM4 ANKMY1 MUC5B PLA2G15 KRIT1 DIP2A TENM4 SPIN1 ALDH7A1	7.25e-08	195	150	11	5092_DN
Disease	Disorder of eye	COL9A2 CDHR1 RGS9 KIF7 UNC119 FREM2 ALMS1 TRIM32 PAX6	1.19e-06	212	146	9	C0015397
Disease	Colorectal Carcinoma	RELCH ERCC6 NRCAM TCOF1 KCNA10 EIF4G1 BUB1B PKHD1 C2CD6 TRAF3IP3 ZSCAN16 DNAH8 BOLL NLRP8	1.10e-05	702	146	14	C0009402
Disease	anemia (implicated_via_orthology)	SLC4A7 SLC4A8 SLC4A10	5.17e-05	15	146	3	DOID:2355 (implicated_via_orthology)
Disease	Pseudoaphakia	ERCC6 GJA8 PAX6	2.23e-04	24	146	3	C0524524
Disease	Lens Opacities	ERCC6 GJA8 PAX6	2.23e-04	24	146	3	C1510497
Disease	Ciliopathies	KIF7 LEFTY2 TRIM32 PKHD1 DNAH8	2.23e-04	110	146	5	C4277690
Disease	Uveoretinal Coloboma	PAX6 ALDH7A1	5.02e-04	7	146	2	C4554007
Disease	Anterior segment dysgenesis	PXDN PAX6	6.68e-04	8	146	2	cv:C1862839
Disease	Cataract	ERCC6 GJA8 PAX6	8.15e-04	37	146	3	C0086543
Disease	Congenital ocular coloboma (disorder)	PAX6 ALDH7A1	8.56e-04	9	146	2	C0009363
Disease	tubal factor infertility, Chlamydophila infectious disease	BMP1 DSG4	8.56e-04	9	146	2	EFO_0021795, EFO_1000863
Disease	refractive error	A2M CDHR1 PLA2G15 KCNA4 PTPRR FER1L4 FRMPD2B	1.23e-03	326	146	7	MONDO_0004892
Disease	hereditary spastic paraplegia (implicated_via_orthology)	ATP13A5 AFG3L2 DNM3	1.27e-03	43	146	3	DOID:2476 (implicated_via_orthology)
Disease	epilepsy (implicated_via_orthology)	NRCAM KCNA4 KCNA10 ATP1B3 ALDH7A1	1.33e-03	163	146	5	DOID:1826 (implicated_via_orthology)
Disease	cannabis dependence measurement	ZEB1 DIP2A PKHD1	1.74e-03	48	146	3	EFO_0008457
Disease	Hypoxanthine measurement	AMIGO1 PKHD1	1.83e-03	13	146	2	EFO_0021604
Disease	hepcidin:ferritin ratio	TACC2 FRMD4B AMIGO1	2.58e-03	55	146	3	EFO_0007901
Disease	Polydactyly	KIF7 FREM2 ALMS1 TRIM32	2.77e-03	117	146	4	C0152427
Disease	Myopia	CDHR1 FRMD4B KCNA4 FER1L4 FRMPD2B ALDH7A1 NLRP8	3.14e-03	385	146	7	HP_0000545
Disease	Bardet-Biedl syndrome 1 (disorder)	KIF7 TRIM32	3.15e-03	17	146	2	C2936862
Disease	velopharyngeal dysfunction	PPL DIP2A FMN1 LILRA4	3.22e-03	122	146	4	EFO_0009336
Disease	Child Behaviour Checklist assessment	LEFTY1 TENM4	3.53e-03	18	146	2	EFO_0005661
Disease	anorectal malformation	MUC5B NLRP8	3.93e-03	19	146	2	MONDO_0019938
Disease	nose morphology measurement, mouth morphology measurement	GDPGP1 TTLL13	4.80e-03	21	146	2	EFO_0007843, EFO_0007955

Protein segments in the cluster

Peptide	Gene	Start	Entry
RQAGRPNKPDSITVV	TNFSF15	166	O95150
PIIRVGGALKAPSQN	BUB1B	241	O60566
SKVPRGPLQGSVEQL	AMER3	281	Q8N944
EGGVPQRPVVFVTRK	APAF1	116	O14727
NTLPVPEATGKGQRR	AMIGO1	461	Q86WK6
VKPSGQGPVRAVVLQ	ATP13A5	356	Q4VNC0
PPQGEILRGLKITVN	CDHR1	371	Q96JP9
TRAPRIGQLQGEIIP	ADAM23	666	O75077
LKVNGPSQPILVRVG	BTNL2	246	Q9UIR0
PAPKRGEIVRQIGDA	ALDH7A1	106	P49419
RQIFIGPPDIKGRAS	AFG3L2	471	Q9Y4W6
QKRGTIENERGKPLP	ALPK2	1586	Q86TB3
GPAIRKQQVGIPRSS	BOLL	106	Q8N9W6
RRLVSQNELPGPGLN	DEPDC4	21	Q8N2C3
LRVPGPADQKTGINI	ALMS1	1831	Q8TCU4
KIAVQPGTVGPQGRR	COL4A2	1396	P08572
GFTLRVGVPNTRPVK	ACAD10	246	Q6JQN1
GSPQLRQVGQIIRVP	ACOT2	46	P49753
GETLPPVGVNRNRIK	ACOT2	331	P49753
GRVAVVIRPPLTQGN	DOP1A	846	Q5JWR5
GIPKPLQRERRAGAE	AOPEP	656	Q8N6M6
SGQPRLRNKVEVDGP	C1orf94	406	Q6P1W5
EVNGVKPPIGQRTRL	BMP1	291	P13497
LGKPADRVNVTVRPG	DDTL	31	A6NHG4
GVPIPNKVIFIRGNE	A2M	376	P01023
EKPRGAGLRVAQKTP	ARHGAP5-AS1	21	Q96IT6
AGKGRVLKRPPNSVV	CKAP2	376	Q8WWK9
RAQAQPGVPLRELGQ	MUC5B	2361	Q9HC84
SIQGRPQDTKPGVKR	RBM33	951	Q96EV2
ARKVTLTRGGLQQPP	RBM33	1021	Q96EV2
NRIPVIGPLKIREQQ	PLA2G15	246	Q8NCC3
VQPLGDVGQQLPRLK	RGS9	611	O75916
RAGQPRLVPGETLEK	FMN1	591	Q68DA7
IQGVIAQPVDRVKRP	KIAA1549	1276	Q9HCM3
QGIPVLVLGNKRDLP	ARL8B	121	Q9NVJ2
QGIPVLVLGNKRDLP	ARL8A	121	Q96BM9
PGQKGRPQKRNIDSR	ERCC6	1001	P0DP91
VNGRPLPDSTRQKIV	PAX6	16	P26367
QPPVALKKEGIRRVG	SERBP1	96	Q8NC51
IIKTFGRVGPNAEPR	RELCH	1066	Q9P260
KGGIQTQLPFQRRRP	ANOS1	411	P23352
PVRQRPDLGSAQKGL	MCM4	111	P33991
VPGRSLAQEKQRPVG	GJC3	261	Q8NFK1
RETPRQTPLLKGQVE	DGKK	621	Q5KSL6
GIVKRAPLVREPGSQ	IL17RA	616	Q96F46
GPRTRVQAENLLKPI	LILRA4	16	P59901
GRLPALEGTLQPQKR	MICAL3	1566	Q7RTP6
ATDVGKRNLPPGIRN	MDN1	886	Q9NU22
KEGGRTRPQVVSLPN	LEFTY1	331	O75610
VIPVGKLFRPNERQV	NCF2	176	P19878
PQKPRGGQRVSDNIK	NEMF	926	O60524
PDVGAGKVQAVNPRI	NRCAM	1056	Q92823
NRIPRGLVQPKKTGS	LIPM	76	Q5VYY2
KRPQGRQPKTVAIQG	NLRP8	196	Q86W28
NPTQAEVLRVLGKPR	MYL3	86	P08590
APVQRPKLRRQGSVV	FRMD8	396	Q9BZ67
QAPRGPQDAVLVRVG	HMCN2	3041	Q8NDA2
LKVSEIAQPGRPRQI	KIAA1109	366	Q2LD37
LVRIRGGAENTAPKP	FREM2	306	Q5SZK8
LQEVERLQRKPGPGA	FER1L4	556	A9Z1Z3
REQFLVPGRPVILKG	KDM8	196	Q8N371
GERVNLTIARPGKPQ	LNX2	411	Q8N448
QETIKAGRIPPLGER	C2CD6	451	Q53TS8
KQRQPEGLGTRFAPV	DSG4	656	Q86SJ6
GTNLPPSRQIVIRKG	DNM3	516	Q9UQ16
SIVDSKPNGVRQRPI	HMGXB3	1206	Q12766
PEGLIQVRGQEARKP	PNMA6E	601	A0A0J9YXQ4
QVRGQEARKPPLEGL	PNMA6E	606	A0A0J9YXQ4
VPESRRPTVEQGLGQ	PLXNB1	1591	O43157
QRLLVAVRDGGQPPL	PCDHGB1	636	Q9Y5G3
TGILRPPLEQGRAVQ	PPL	526	O60437
NEPPQGVRAGLKRTF	DNAH8	4016	Q96JB1
LGKPADRVNVTVRPG	DDT	31	P30046
IQNVPLEDRVRGPKG	HNRNPU	476	Q00839
PRVPAGVNRNRKTNG	GOLGA8Q	26	H3BV12
DPGVIPINSRGEKQR	DIP2B	1541	Q9P265
VGGSKARVQARQVPP	KIF7	681	Q2M1P5
GEARPGPKTAVQIRV	LARP6	6	Q9BRS8
TKPISPANQGIRGKR	KRIT1	76	O00522
ERGVQRRPPQTIKSV	GDPGP1	101	Q6ZNW5
KGPRLGQRLPSIVVE	LBHD2	31	A0A0U1RRK4
PKEAGKQPRTVIIQG	NLRP4	141	Q96MN2
KQPRTVIIQGPQGIG	NLRP4	146	Q96MN2
QRLLVAVRDGGQPPL	PCDHGB5	636	Q9Y5G0
RDVKPENFLIGRPGN	CSNK1G3	161	Q9Y6M4
PKVLNVVVDPQGRGA	PTPRR	296	Q15256
VPKVGQRFNRIGLPP	PI4K2A	241	Q9BTU6
GLVRKPQPIRLSGVD	FANCD2OS	86	Q96PS1
QSGGKIRRPANVPID	KCNA10	146	Q16322
VKIRERPPGQRQASD	CD2BP2	126	O95400
GEKPPQVRRRVGTAF	FRMD4B	471	Q9Y2L6
NRILQISPEGPLQGR	DOCK10	286	Q96BY6
APGVGSVEQTPRKRL	CDKN1C	301	P49918
ENLLRVGGAPTPRLQ	DBX2	41	Q6ZNG2
RIKRLFPGQPAEENG	FRMPD2B	121	Q6IN97
VVRSVRPGGPSENKL	FRMPD3	76	Q5JV73
EQSPQGRPVGTRQKK	FNDC4	211	Q9H6D8
RTVQQIPGVGKVKAP	FAAP24	161	Q9BTP7
PVQRGLGRKPLDISV	BCL9	836	O00512
GIRSALKRPVEQPLG	GJA8	231	P48165
QVVVLALAQIRGPPG	COL9A2	16	Q14055
SLPRGLDVKEQGQIP	ANKMY1	861	Q9P2S6
GIPNARKLGEPIRAA	CEP95	246	Q96GE4
VEVVRNKPVARQAPG	DNAJB11	151	Q9UBS4
VPRRGDQGPKTIDQI	EIF4G1	991	Q04637
KEGGRTRPQVVSLPN	LEFTY2	331	O00292
SPGGAVRPLLKRLQQ	CUL9	976	Q8IWT3
DPGVIPINSRGEKQR	DIP2A	1536	Q14689
VGITARNIPRGPQLA	HMBS	316	P08397
PRVPAGVNRNRKTNG	GOLGA8R	26	I6L899
PRVPAGVNRNRKTNG	GOLGA8O	26	A6NCC3
EDVFPNQPGGIRILK	DERL2	186	Q9GZP9
QTAVQLPPQRRLIGK	GSTCD	576	Q8NEC7
GIEQKRPGRPLNITS	PIAS2	251	O75928
QLLVRIRGGAENTPP	FREM3	291	P0C091
QLVKQLRTERPSGPG	TRIM27	76	P14373
VGPLQIGQAVKKPRT	TRIM32	286	Q13049
PGEQPKFLGIREQRV	SLC4A7	996	Q9Y6M7
KVGRPSNIGQAQPII	PUF60	201	Q9UHX1
VAPVRVGTQAPRKAG	TCOF1	656	Q13428
TQGPRVPIILVGNKS	RHOT2	106	Q8IXI1
LGKPGRIQLQGPVRQ	TAF1C	256	Q15572
IAGVLVPAKDQPGRQ	EPPK1	2226	P58107
KDVRLTTPQPGNRGL	PKHD1	316	P08F94
PGEQPKFLGIREQRV	SLC4A8	866	Q2Y0W8
GRTVVVVNNPRAPLG	SRCAP	1006	Q6ZRS2
RRQPGAAPLGKVLVD	PROB1	871	E7EW31
NTEGNIGIRIKPVRP	ACSM1	411	Q08AH1
NRIIGLKPEGVPRID	ATP1B3	176	P54709
GVQGRQPLTEGPRVI	TP53TG5	171	Q9Y2B4
GPKNPRVSRVTVQLE	TBX10	56	O75333
VVRSPEGTPQKIRQL	ZC3HC1	21	Q86WB0
EQGPSRRPGQVTVLK	TRAF3IP3	86	Q9Y228
QQLLRKLGVRPPASG	TIMELESS	1061	Q9UNS1
GPEGRLQQVPELKNR	TBC1D17	291	Q9HA65
KGNQVVDPRLRTIPR	ZC3H6	751	P61129
RKQPIGPEDVLGLQR	UNC119	56	Q13432
LAGQGAAVLPQVRPK	PHF21B	61	Q96EK2
GPSKPVSQPRRNIVG	SPIN1	41	Q9Y657
GDEVVLRQKPPTGRK	ARHGAP23	486	Q9P227
DSGIRVAQKQEPRVP	SPATA31D1	1261	Q6ZQQ2
VNRVSPVRPKGGELD	SPATA31D1	1291	Q6ZQQ2
LRGLPPGTQIQIKVQ	ROBO3	731	Q96MS0
APGEQPKFLGIREQR	SLC4A10	896	Q6U841
LIVSRERLVPPGGNK	SPPL2B	116	Q8TCT7
LRQGIVQRSGKPLLP	PXDN	936	Q92626
IDVGRRASQKIPPGT	TENM4	436	Q6N022
GRVQNSPPVGRKTLP	TACC2	2221	O95359
ANGEGRVKVVPINTP	WDR6	411	Q9NNW5
IPVNGRPRTGLKTSQ	ZEB1	296	P37275
GEKPLKRQEGRVPVL	ZNF773	121	Q6PK81
PGKQVPGNSERRDIL	ZSCAN16	126	Q9H4T2
KQRFPNIRLPRGEVG	PIPOX	126	Q9P0Z9
LPGTQVTRKEPGALR	TRANK1	666	O15050
KRRGELEPQLGSPQQ	VWA8	1696	A3KMH1
PPVRRVRVVKQEAGG	SNTB2	111	Q13425
VPQLQEGQGDIPKRV	ZFYVE26	36	Q68DK2
LVPKENPGRGQVFVE	UHMK1	361	Q8TAS1
PSVRVQPGRGKLQGQ	nan	196	Q6ZTC4
GIFITRNPREIKPGE	TTLL13	211	A6NNM8
PRVPAGVNRNRKTNG	GOLGA8N	26	F8WBI6
QSGGRLKRPVNVPFD	KCNA4	236	P22459