Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionSUMO ligase activity

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3 TRIM60

4.19e-11201367GO:0061665
GeneOntologyMolecularFunctionSUMO transferase activity

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3 TRIM60

4.12e-09361367GO:0019789
GeneOntologyMolecularFunctionpeptidyl-prolyl cis-trans isomerase activity

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

1.11e-06501366GO:0003755
GeneOntologyMolecularFunctioncis-trans isomerase activity

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

1.58e-06531366GO:0016859
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 MCF2 RCBTB2 OCRL CHRM4 PREX2 RGPD3 ARHGEF4 PREX1 AGAP1 RGPD5

1.97e-0650713615GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 MCF2 RCBTB2 OCRL CHRM4 PREX2 RGPD3 ARHGEF4 PREX1 AGAP1 RGPD5

1.97e-0650713615GO:0030695
GeneOntologyMolecularFunctionGTPase activator activity

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 OCRL PREX2 RGPD3 PREX1 AGAP1 RGPD5

3.38e-0627913611GO:0005096
GeneOntologyMolecularFunctionubiquitin-like protein ligase activity

RGPD4 UBR1 RGPD2 RANBP2 MED30 RGPD8 LONRF1 RGPD1 ZZEF1 RGPD3 CCAR1 TRIM60

1.83e-0539813612GO:0061659
GeneOntologyMolecularFunctionubiquitin-like protein transferase activity

RGPD4 UBR1 RGPD2 RANBP2 MED30 RGPD8 LONRF1 RGPD1 ZZEF1 RGPD3 CCAR1 TRIM60

2.02e-0451213612GO:0019787
GeneOntologyMolecularFunctionnuclear vitamin D receptor binding

MED30 RXRA MED13

2.34e-04181363GO:0042809
GeneOntologyMolecularFunctionaminoacyltransferase activity

RGPD4 UBR1 RGPD2 RANBP2 MED30 RGPD8 LONRF1 RGPD1 ZZEF1 RGPD3 CCAR1 TRIM60

2.87e-0453213612GO:0016755
GeneOntologyMolecularFunctionisomerase activity

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RPUSD1 RGPD3

3.50e-041921367GO:0016853
GeneOntologyMolecularFunctionsmall GTPase binding

RGPD4 RGPD2 RANBP2 RGPD8 MYO1C VPS4A RGPD1 OCRL RGPD3

3.60e-043211369GO:0031267
GeneOntologyMolecularFunctionnuclear receptor coactivator activity

MED30 BUD31 CCAR1 MED13

7.95e-04611364GO:0030374
GeneOntologyMolecularFunctionGTPase binding

RGPD4 RGPD2 RANBP2 RGPD8 MYO1C VPS4A RGPD1 OCRL RGPD3

8.19e-043601369GO:0051020
GeneOntologyMolecularFunctionacyltransferase activity

RGPD4 UBR1 RGPD2 RANBP2 MED30 RGPD8 LONRF1 RGPD1 HAT1 ZZEF1 RGPD3 MSL3 CCAR1 TRIM60

8.36e-0477513614GO:0016746
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor binding

HSP90B2P LANCL1 APOB

1.58e-03341363GO:0050750
GeneOntologyMolecularFunctionnuclear thyroid hormone receptor binding

MED30 RXRA MED13

1.58e-03341363GO:0046966
GeneOntologyMolecularFunctionenzyme activator activity

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 OCRL EPGN PREX2 RGPD3 PREX1 AGAP1 RGPD5

1.78e-0365613612GO:0008047
GeneOntologyBiologicalProcesspositive regulation of glucokinase activity

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

6.35e-1291376GO:0033133
GeneOntologyBiologicalProcesspositive regulation of hexokinase activity

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

1.58e-11101376GO:1903301
GeneOntologyBiologicalProcessNLS-bearing protein import into nucleus

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3 RGPD5

3.52e-11201377GO:0006607
GeneOntologyBiologicalProcessregulation of glucokinase activity

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

1.27e-10131376GO:0033131
GeneOntologyBiologicalProcessregulation of hexokinase activity

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

2.21e-10141376GO:1903299
GeneOntologyBiologicalProcessprotein peptidyl-prolyl isomerization

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

1.78e-07381376GO:0000413
GeneOntologyBiologicalProcesspeptidyl-proline modification

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

1.53e-06541376GO:0018208
GeneOntologyBiologicalProcessRNA localization

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 MAGOHB SHQ1 RGPD3 ATM SMG6

1.94e-0621713710GO:0006403
GeneOntologyBiologicalProcessestablishment of RNA localization

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 MAGOHB RGPD3 ATM SMG6

3.01e-061781379GO:0051236
GeneOntologyBiologicalProcessmRNA transport

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 MAGOHB RGPD3 SMG6

5.72e-061451378GO:0051028
GeneOntologyBiologicalProcessregulation of gluconeogenesis

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

7.73e-06711376GO:0006111
GeneOntologyBiologicalProcessRNA transport

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 MAGOHB RGPD3 SMG6

2.26e-051751378GO:0050658
GeneOntologyBiologicalProcessnucleic acid transport

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 MAGOHB RGPD3 SMG6

2.26e-051751378GO:0050657
GeneOntologyBiologicalProcessnuclear export

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 MAGOHB RGPD3 SMG6

3.36e-051851378GO:0051168
GeneOntologyBiologicalProcessprotein folding

RGPD4 DNAJB12 RGPD2 RANBP2 HSP90B2P RGPD8 RGPD1 DNAJC18 RGPD3

4.02e-052461379GO:0006457
GeneOntologyBiologicalProcessgluconeogenesis

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

9.84e-051111376GO:0006094
GeneOntologyBiologicalProcesshexose biosynthetic process

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

1.20e-041151376GO:0019319
GeneOntologyBiologicalProcessmonosaccharide biosynthetic process

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

1.58e-041211376GO:0046364
GeneOntologyBiologicalProcesssomatic hypermutation of immunoglobulin genes

AICDA SAMHD1 MSH2

1.82e-04171373GO:0016446
GeneOntologyBiologicalProcesssomatic diversification of immune receptors via somatic mutation

AICDA SAMHD1 MSH2

2.17e-04181373GO:0002566
GeneOntologyBiologicalProcessregulation of carbohydrate biosynthetic process

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

2.54e-041321376GO:0043255
GeneOntologyBiologicalProcessimmune system development

AICDA RCBTB2 SAMHD1 MSH2 TLX1 CCR4 ATM IL7R

2.57e-042481378GO:0002520
GeneOntologyBiologicalProcessnucleobase-containing compound transport

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 MAGOHB RGPD3 SMG6

2.64e-042491378GO:0015931
GeneOntologyBiologicalProcessregulation of glucose metabolic process

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

2.75e-041341376GO:0010906
GeneOntologyBiologicalProcessprotein import into nucleus

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3 RGPD5

3.31e-041951377GO:0006606
GeneOntologyBiologicalProcessimport into nucleus

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3 RGPD5

3.97e-042011377GO:0051170
GeneOntologyBiologicalProcessphosphatidylinositol-3-phosphate biosynthetic process

OCRL PIK3C2B ATM

4.02e-04221373GO:0036092
GeneOntologyCellularComponentcytoplasmic periphery of the nuclear pore complex

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

1.97e-1281376GO:1990723
GeneOntologyCellularComponentnuclear pore cytoplasmic filaments

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

1.46e-11101376GO:0044614
GeneOntologyCellularComponentannulate lamellae

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

2.04e-10141376GO:0005642
GeneOntologyCellularComponentnuclear pore nuclear basket

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

1.23e-09181376GO:0044615
GeneOntologyCellularComponentnuclear inclusion body

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

2.55e-09201376GO:0042405
GeneOntologyCellularComponentSUMO ligase complex

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

3.55e-09211376GO:0106068
GeneOntologyCellularComponentnuclear pore

RGPD4 RGPD2 RANBP2 RGPD8 VPS4A RGPD1 RGPD3 RGPD5

3.35e-071011378GO:0005643
GeneOntologyCellularComponentinclusion body

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

2.81e-05901376GO:0016234
GeneOntologyCellularComponentnuclear protein-containing complex

RGPD4 RGPD2 RANBP2 MED30 RGPD8 MYO1C VPS4A MIS18A RGPD1 MAGOHB MSH2 ELL3 RXRA NUFIP1 RGPD3 BUD31 SLC5A8 ANAPC5 UTY MED13 SMG6 RGPD5 RBM17

3.01e-05137713723GO:0140513
GeneOntologyCellularComponentnuclear envelope

RGPD4 DNAJB12 RGPD2 RANBP2 RGPD8 VPS4A RGPD1 PTGER3 RGPD3 CCAR1 SCAI RGPD5

3.24e-0456013712GO:0005635
GeneOntologyCellularComponentnuclear membrane

RGPD4 DNAJB12 RGPD2 RANBP2 RGPD8 RGPD1 PTGER3 RGPD3 SCAI

5.01e-043491379GO:0031965
GeneOntologyCellularComponenteukaryotic translation initiation factor 3 complex, eIF3m

EIF3CL EIF3C

1.49e-0391372GO:0071541
MousePhenoelevated level of mitotic sister chromatid exchange

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

9.82e-10161026MP:0003701
MousePhenoincreased sarcoma incidence

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 HAT1 RCBTB2 MSH2 RGPD3 ATM

3.34e-0910210210MP:0002032
MousePhenoabnormal tumor latency

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 MSH2 RGPD3

4.09e-09341027MP:0010307
MousePhenoincreased hepatobiliary system tumor incidence

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 HAT1 RCBTB2 MSH2 RGPD3 ATM

7.64e-0911110210MP:0010297
MousePhenoincreased liver tumor incidence

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 HAT1 RCBTB2 MSH2 RGPD3 ATM

7.64e-0911110210MP:0008019
MousePhenoabnormal morula morphology

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

2.66e-08261026MP:0012058
MousePhenodecreased tumor latency

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

6.70e-08301026MP:0010308
MousePhenofailure of blastocyst formation

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

8.26e-08311026MP:0012129
MousePhenoabnormal blastocyst formation

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

3.49e-07391026MP:0012128
MousePhenoabnormal mitosis

RGPD4 RGPD2 RANBP2 RGPD8 MIS18A RGPD1 HAT1 RGPD3 PKHD1

3.81e-071281029MP:0004046
MousePhenoincreased hepatocellular carcinoma incidence

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3 ATM

7.36e-07701027MP:0003331
MousePhenoincreased respiratory system tumor incidence

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 MSH2 TGFBI RGPD3

1.09e-061071028MP:0010298
MousePhenoincreased lung tumor incidence

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 MSH2 TGFBI RGPD3

1.09e-061071028MP:0008014
MousePhenoincreased malignant tumor incidence

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 HAT1 RCBTB2 MSH2 TGFBI RGPD3 ATM

1.21e-0623710211MP:0002018
MousePhenoincreased lung carcinoma incidence

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 TGFBI RGPD3

1.55e-06781027MP:0008714
MousePhenoabnormal chromosome morphology

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 TGFBI RGPD3 ATM

3.76e-061261028MP:0003702
MousePhenoaneuploidy

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

5.22e-06611026MP:0004024
MousePhenoabnormal cell nucleus morphology

RGPD4 RGPD2 RANBP2 RPL38 RGPD8 RGPD1 TGFBI RGPD3 ATM

7.80e-061841029MP:0003111
MousePhenoincreased incidence of tumors by chemical induction

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 MSH2 TGFBI RGPD3

8.67e-061411028MP:0004499
MousePhenoabnormal intracellular organelle morphology

RGPD4 RGPD2 RANBP2 MED30 RPL38 RGPD8 RGPD1 HAT1 LANCL1 ADGRG6 TGFBI RGPD3 ABCD3 ZFYVE26 ATM

9.37e-0654610215MP:0014239
MousePhenobelly spot

RPL38 MYO10 EIF3CL ADAMTS20 EIF3C

1.14e-05411025MP:0000373
MousePhenoincreased carcinoma incidence

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 MSH2 TGFBI RGPD3 ATM

1.35e-051971029MP:0002038
MousePhenoincreased classified tumor incidence

RGPD4 RGPD2 RANBP2 RGPD8 ESR2 RGPD1 HAT1 RCBTB2 MSH2 TGFBI RGPD3 ATM

2.10e-0538110212MP:0010273
MousePhenoabnormal classified tumor incidence

RGPD4 RGPD2 RANBP2 RGPD8 ESR2 RGPD1 HAT1 RCBTB2 MSH2 TGFBI RGPD3 ATM

2.26e-0538410212MP:0020188
MousePhenoabnormal rod electrophysiology

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3 STRA6

2.57e-051191027MP:0004021
MousePhenoincreased organ/body region tumor incidence

RGPD4 RGPD2 RANBP2 RGPD8 ESR2 RGPD1 HAT1 RCBTB2 MSH2 TGFBI RGPD3 ATM

2.99e-0539510212MP:0010274
MousePhenowhite spotting

RPL38 MYO10 EIF3CL ADAMTS20 EIF3C

3.06e-05501025MP:0002938
MousePhenoabnormal organ/body region tumor incidence

RGPD4 RGPD2 RANBP2 RGPD8 ESR2 RGPD1 HAT1 RCBTB2 MSH2 TGFBI RGPD3 ATM

3.46e-0540110212MP:0013152
MousePhenoabnormal chromosome number

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

3.82e-05861026MP:0004023
MousePhenoincreased incidence of induced tumors

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 MSH2 TGFBI RGPD3

3.82e-051731028MP:0002021
MousePhenoenlarged epididymis

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

8.43e-05991026MP:0004931
MousePhenoabnormal cell cycle

RGPD4 RGPD2 RANBP2 RGPD8 MIS18A RGPD1 HAT1 RGPD3 ASPM PKHD1 ATM SMC1B SCAI

1.02e-0452010213MP:0003077
MousePhenofailure of blastocyst to hatch from the zona pellucida

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

1.30e-041071026MP:0003694
MousePhenoabnormal incidence of induced tumors

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 DNAJC27 MSH2 TGFBI RGPD3

1.52e-042691029MP:0013151
MousePhenoabnormal epididymis morphology

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 LANCL1 ADGRG2 TK1 RGPD3

1.52e-042691029MP:0002631
MousePhenoabnormal blastocyst hatching

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

1.75e-041131026MP:0003693
MousePhenoabnormal epididymis size

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 ADGRG2 RGPD3

2.10e-041661027MP:0004926
MousePhenoincreased physiological sensitivity to xenobiotic

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 LANCL1 MSH2 TGFBI RGPD3

2.41e-042861029MP:0008873
MousePhenoabnormal preimplantation embryo development

RGPD4 RGPD2 RANBP2 RPL38 RGPD8 RGPD1 RGPD3

2.52e-041711027MP:0009781
MousePhenoabnormal physiological response to xenobiotic

RGPD4 RGPD2 RANBP2 RGPD8 ESR2 RGPD1 LANCL1 DNAJC27 MSH2 ACE PTGER3 TGFBI RGPD3 PLA2G5

3.11e-0466210214MP:0008872
MousePhenoneoplasm

RGPD4 RGPD2 RANBP2 RGPD8 ESR2 RGPD1 HAT1 DNAJC27 RCBTB2 MSH2 ACE TGFBI RGPD3 ATM ARHGEF4

3.26e-0474710215MP:0002006
MousePhenoincreased tumor incidence

RGPD4 RGPD2 RANBP2 RGPD8 ESR2 RGPD1 HAT1 RCBTB2 MSH2 TGFBI RGPD3 ATM

4.71e-0453010212MP:0002020
MousePhenoabnormal hallux morphology

EIF3CL EIF3C

5.20e-0451022MP:0009049
MousePhenoabnormal tumor incidence

RGPD4 RGPD2 RANBP2 RGPD8 ESR2 RGPD1 HAT1 DNAJC27 RCBTB2 MSH2 TGFBI RGPD3 ATM

7.02e-0463510213MP:0002019
MousePhenopersistent hyperplastic primary vitreous

RXRA STRA6

7.76e-0461022MP:0010711
MousePhenocomplete atrioventricular septal defect

IFT172 RXRA DNAH5

8.68e-04261023MP:0010413
MousePhenoabnormal tumor susceptibility

RGPD4 RGPD2 RANBP2 RGPD8 ESR2 RGPD1 HAT1 DNAJC27 RCBTB2 MSH2 TGFBI RGPD3 ATM

8.71e-0465010213MP:0002166
DomainRan_BP1

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3 RGPD5

6.42e-13121347PF00638
DomainRANBD1

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3 RGPD5

6.42e-13121347PS50196
DomainRanBD

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3 RGPD5

1.38e-12131347SM00160
DomainRan_bind_dom

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3 RGPD5

1.38e-12131347IPR000156
DomainGrip

RGPD4 RGPD2 RGPD8 RGPD1 RGPD3 RGPD5

5.47e-11111346SM00755
DomainGRIP

RGPD4 RGPD2 RGPD8 RGPD1 RGPD3 RGPD5

5.47e-11111346PF01465
DomainGRIP_dom

RGPD4 RGPD2 RGPD8 RGPD1 RGPD3 RGPD5

1.09e-10121346IPR000237
DomainGRIP

RGPD4 RGPD2 RGPD8 RGPD1 RGPD3 RGPD5

1.09e-10121346PS50913
DomainRab_bind

RGPD4 RGPD2 RGPD8 RGPD1 RGPD3

3.66e-1071345PF16704
DomainGCC2_Rab_bind

RGPD4 RGPD2 RGPD8 RGPD1 RGPD3

3.66e-1071345IPR032023
DomainTPR-like_helical_dom

RGPD4 RGPD2 SH3TC2 RANBP2 RGPD8 LONRF1 IFT172 RGPD1 RMDN3 RGPD3 ANAPC5 UTY SMG6 RGPD5

1.36e-0923313414IPR011990
DomainTPR_REGION

RGPD4 RGPD2 SH3TC2 RANBP2 RGPD8 LONRF1 IFT172 RGPD1 RGPD3 ANAPC5 UTY RGPD5

2.51e-0916513412PS50293
DomainTPR

RGPD4 RGPD2 SH3TC2 RANBP2 RGPD8 LONRF1 IFT172 RGPD1 RGPD3 ANAPC5 UTY RGPD5

2.51e-0916513412PS50005
Domain-

RGPD4 RGPD2 RGPD8 RGPD1 RGPD3

4.32e-091013451.10.220.60
DomainTPR-contain_dom

RGPD4 RGPD2 SH3TC2 RANBP2 RGPD8 LONRF1 RGPD1 RGPD3 ANAPC5 UTY RGPD5

1.09e-0815013411IPR013026
DomainTPR

RGPD4 RGPD2 SH3TC2 RANBP2 RGPD8 LONRF1 RGPD1 RGPD3 ANAPC5 UTY

3.07e-0812913410SM00028
Domain-

RGPD4 RGPD2 SH3TC2 RANBP2 RGPD8 LONRF1 RGPD1 RMDN3 RGPD3 ANAPC5 UTY SMG6

3.22e-08207134121.25.40.10
DomainTPR_repeat

RGPD4 RGPD2 SH3TC2 RANBP2 RGPD8 LONRF1 RGPD1 RGPD3 ANAPC5 UTY

4.11e-0813313410IPR019734
DomainPH_dom-like

RGPD4 RGPD2 RANBP2 RGPD8 MYO10 RGPD1 MCF2 PREX2 RTKN2 RGPD3 ARHGEF4 PREX1 AGAP1 RGPD5

2.37e-0642613414IPR011993
Domain-

RGPD4 RGPD2 RANBP2 RGPD8 MYO10 RGPD1 MCF2 PREX2 RTKN2 RGPD3 ARHGEF4 PREX1 AGAP1

4.88e-06391134132.30.29.30
DomainTPR_1

SH3TC2 RANBP2 RGPD8 RGPD1 UTY RGPD5

4.63e-05901346IPR001440
DomainTPR_1

SH3TC2 RANBP2 RGPD8 RGPD1 UTY RGPD5

4.63e-05901346PF00515
DomainEIF3C_N_dom

EIF3CL EIF3C

5.11e-0521342IPR008905
DomaineIF-3c_N

EIF3CL EIF3C

5.11e-0521342PF05470
DomainEIF3C

EIF3CL EIF3C

5.11e-0521342IPR027516
DomainDUF1977

DNAJB12 DNAJC18

1.53e-0431342PF09320
DomainDUF1977_DnaJ-like

DNAJB12 DNAJC18

1.53e-0431342IPR015399
DomainGDS_CDC24_CS

MCF2 PREX2 ARHGEF4 PREX1

1.71e-04391344IPR001331
DomainAnoct_dimer

ANO4 ANO1

1.05e-0371342PF16178
DomainAnoct_dimer

ANO4 ANO1

1.05e-0371342IPR032394
DomainDH_1

MCF2 PREX2 ARHGEF4 PREX1

1.09e-03631344PS00741
DomainP-loop_NTPase

MYO1C MYO10 VPS4A BMS1 DNAJC27 MSH2 PFKFB2 GTPBP10 SBNO2 TK1 ASPM ABCD3 DNAH5 SMC1B AGAP1

1.13e-0384813415IPR027417
DomainPH

MYO10 MCF2 PREX2 RTKN2 ARHGEF4 PREX1 AGAP1

1.34e-032291347PF00169
DomainRhoGEF

MCF2 PREX2 ARHGEF4 PREX1

1.45e-03681344SM00325
DomainRhoGEF

MCF2 PREX2 ARHGEF4 PREX1

1.61e-03701344PF00621
DomainDH_2

MCF2 PREX2 ARHGEF4 PREX1

1.61e-03701344PS50010
Domain-

MCF2 PREX2 ARHGEF4 PREX1

1.70e-037113441.20.900.10
DomainDH-domain

MCF2 PREX2 ARHGEF4 PREX1

1.70e-03711344IPR000219
DomainAnoctamin

ANO4 ANO1

2.21e-03101342PF04547
DomainAnoctamin

ANO4 ANO1

2.21e-03101342IPR007632
DomainPH

MYO10 MCF2 PREX2 RTKN2 ARHGEF4 PREX1 AGAP1

3.96e-032781347SM00233
DomainPH_DOMAIN

MYO10 MCF2 PREX2 RTKN2 ARHGEF4 PREX1 AGAP1

4.04e-032791347PS50003
DomainPH_domain

MYO10 MCF2 PREX2 RTKN2 ARHGEF4 PREX1 AGAP1

4.12e-032801347IPR001849
DomainDnaJ

DNAJB12 DNAJC18 DNAJC27

4.93e-03481343PF00226
DomainPI3/4_kinase_CS

PIK3C2B ATM

5.05e-03151342IPR018936
DomainDNAJ_1

DNAJB12 DNAJC18 DNAJC27

5.23e-03491343PS00636
DomainDNAJ_2

DNAJB12 DNAJC18 DNAJC27

5.23e-03491343PS50076
DomainDnaJ

DNAJB12 DNAJC18 DNAJC27

5.23e-03491343SM00271
Domain-

DNAJB12 DNAJC18 DNAJC27

5.23e-034913431.10.287.110
Domain-

PIK3C2B ATM

5.74e-031613421.10.1070.11
DomainPI3Kc

PIK3C2B ATM

5.74e-03161342SM00146
DomainPINT

EIF3CL EIF3C

5.74e-03161342SM00088
DomainDnaJ_domain

DNAJB12 DNAJC18 DNAJC27

5.85e-03511343IPR001623
DomainPCI_dom

EIF3CL EIF3C

6.48e-03171342IPR000717
DomainPCI

EIF3CL EIF3C

6.48e-03171342PF01399
PathwayBIOCARTA_RANBP2_PATHWAY

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

1.68e-0918986MM1549
PathwayREACTOME_NUCLEAR_PORE_COMPLEX_NPC_DISASSEMBLY

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

3.07e-0740986MM14945
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_SMALL_RNAS

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

3.57e-0741986MM15200
PathwayREACTOME_SUMOYLATION_OF_SUMOYLATION_PROTEINS

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

4.14e-0742986MM15039
PathwayREACTOME_TRANSPORT_OF_THE_SLBP_DEPENDANT_MATURE_MRNA

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

4.79e-0743986MM14609
PathwayREACTOME_SUMOYLATION_OF_UBIQUITINYLATION_PROTEINS

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

8.25e-0747986MM14939
PathwayREACTOME_GENE_SILENCING_BY_RNA

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

1.06e-0649986MM14837
PathwayREACTOME_TRANSPORT_OF_MATURE_MRNAS_DERIVED_FROM_INTRONLESS_TRANSCRIPTS

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

1.20e-0650986MM14610
PathwayREACTOME_SUMOYLATION_OF_DNA_REPLICATION_PROTEINS

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

1.35e-0651986MM15151
PathwayREACTOME_GLUCOSE_METABOLISM

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 PFKFB2 RGPD3

1.57e-0682987MM15394
PathwayREACTOME_NUCLEAR_ENVELOPE_BREAKDOWN

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

2.13e-0655986MM14917
PathwayREACTOME_SUMOYLATION_OF_RNA_BINDING_PROTEINS

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

2.92e-0658986MM15149
PathwayREACTOME_SNRNP_ASSEMBLY

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

2.92e-0658986MM14736
PathwayREACTOME_SUMOYLATION_OF_CHROMATIN_ORGANIZATION_PROTEINS

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

5.74e-0665986MM15147
PathwayREACTOME_REGULATION_OF_HSF1_MEDIATED_HEAT_SHOCK_RESPONSE

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

1.13e-0573986MM14948
PathwayREACTOME_MITOTIC_SPINDLE_CHECKPOINT

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3 ANAPC5

1.68e-05117987MM15387
PathwayREACTOME_SUMOYLATION_OF_DNA_DAMAGE_RESPONSE_AND_REPAIR_PROTEINS

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

2.54e-0584986MM14929
PathwayREACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

2.90e-0586986MM15413
PathwayREACTOME_CELLULAR_RESPONSE_TO_HEAT_STRESS

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

4.26e-0592986MM14951
PathwayREACTOME_RHO_GTPASES_ACTIVATE_FORMINS

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3 SCAI

5.59e-05141987MM15266
PathwayREACTOME_AMPLIFICATION_OF_SIGNAL_FROM_THE_KINETOCHORES

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

6.81e-05100986MM14561
PathwayREACTOME_MITOTIC_PROPHASE

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

1.41e-04114986MM15361
PathwayREACTOME_SUMOYLATION

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RXRA RGPD3

1.74e-04169987MM14919
PathwayREACTOME_MITOTIC_METAPHASE_AND_ANAPHASE

RGPD4 RGPD2 RANBP2 RGPD8 VPS4A RGPD1 RGPD3 ANAPC5

2.23e-04234988MM14898
PathwayREACTOME_RESOLUTION_OF_SISTER_CHROMATID_COHESION

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

2.76e-04129986MM14894
PathwayREACTOME_SEPARATION_OF_SISTER_CHROMATIDS

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3 ANAPC5

3.91e-04193987MM14890
PathwayREACTOME_CELL_CYCLE_CHECKPOINTS

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3 ATM ANAPC5

5.94e-04271988MM15388
PathwayREACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3 BUD31 RBM17

6.86e-04277988MM15414
PathwayREACTOME_CELLULAR_RESPONSES_TO_STIMULI

RGPD4 RGPD2 RANBP2 RGPD8 MINK1 RGPD1 APOB RXRA RGPD3 ATM ANAPC5

7.51e-045059811MM15548
PathwayREACTOME_CELL_CYCLE

RGPD4 RGPD2 RANBP2 RGPD8 VPS4A MIS18A RGPD1 SHQ1 FBXL7 RGPD3 ATM ANAPC5

9.47e-046039812MM14635
PathwayREACTOME_METABOLISM_OF_RNA

RGPD4 RGPD2 RANBP2 RPL38 RGPD8 BMS1 RGPD1 RGPD3 BUD31 UTP20 SMG6 RBM17

1.08e-036129812MM15547
Pubmed

Interconversion of red opsin isoforms by the cyclophilin-related chaperone protein Ran-binding protein 2.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

2.44e-14713869037092
Pubmed

Complex genomic rearrangements lead to novel primate gene function.

RGPD4 RGPD2 RGPD8 RGPD1 RGPD3 RGPD5

2.44e-147138615710750
Pubmed

Genomic organization, expression, and localization of murine Ran-binding protein 2 (RanBP2) gene.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

2.44e-147138611353387
Pubmed

Microglial activation in an amyotrophic lateral sclerosis-like model caused by Ranbp2 loss and nucleocytoplasmic transport impairment in retinal ganglion neurons.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

2.44e-147138630944974
Pubmed

Nucleoporin Nup358 drives the differentiation of myeloid-biased multipotent progenitors by modulating HDAC3 nuclear translocation.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

2.44e-147138638838144
Pubmed

Retina-specifically expressed novel subtypes of bovine cyclophilin.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

2.44e-14713867559465
Pubmed

Mst1, RanBP2 and eIF4G are new markers for in vivo PI3K activation in murine and human prostate.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

2.44e-147138617372272
Pubmed

Proteostatic Remodeling of Small Heat Shock Chaperones─Crystallins by Ran-Binding Protein 2─and the Peptidyl-Prolyl cis-trans Isomerase and Chaperone Activities of Its Cyclophilin Domain.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

2.44e-147138638657106
Pubmed

Nup358, a nucleoporin, functions as a key determinant of the nuclear pore complex structure remodeling during skeletal myogenesis.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

2.44e-147138621205196
Pubmed

Haploinsufficiency of RanBP2 is neuroprotective against light-elicited and age-dependent degeneration of photoreceptor neurons.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

2.44e-147138618949001
Pubmed

Selective impairment of a subset of Ran-GTP-binding domains of ran-binding protein 2 (Ranbp2) suffices to recapitulate the degeneration of the retinal pigment epithelium (RPE) triggered by Ranbp2 ablation.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

2.44e-147138625187515
Pubmed

Localization of the Ran-GTP binding protein RanBP2 at the cytoplasmic side of the nuclear pore complex.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

2.44e-14713868603673
Pubmed

Uncoupling phototoxicity-elicited neural dysmorphology and death by insidious function and selective impairment of Ran-binding protein 2 (Ranbp2).

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

2.44e-147138626632511
Pubmed

Differential loss of prolyl isomerase or chaperone activity of Ran-binding protein 2 (Ranbp2) unveils distinct physiological roles of its cyclophilin domain in proteostasis.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

2.44e-147138624403063
Pubmed

Distinct and atypical intrinsic and extrinsic cell death pathways between photoreceptor cell types upon specific ablation of Ranbp2 in cone photoreceptors.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

2.44e-147138623818861
Pubmed

Kinesin-1 and mitochondrial motility control by discrimination of structurally equivalent but distinct subdomains in Ran-GTP-binding domains of Ran-binding protein 2.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

2.44e-147138623536549
Pubmed

Identification of RanBP2- and kinesin-mediated transport pathways with restricted neuronal and subcellular localization.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

2.44e-147138612191015
Pubmed

Ranbp2 haploinsufficiency mediates distinct cellular and biochemical phenotypes in brain and retinal dopaminergic and glia cells elicited by the Parkinsonian neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

2.44e-147138622821000
Pubmed

Neuroprotection resulting from insufficiency of RANBP2 is associated with the modulation of protein and lipid homeostasis of functionally diverse but linked pathways in response to oxidative stress.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

2.44e-147138620682751
Pubmed

The nucleoporin RanBP2 tethers the cAMP effector Epac1 and inhibits its catalytic activity.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

9.73e-148138621670213
Pubmed

Critical role of RanBP2-mediated SUMOylation of Small Heterodimer Partner in maintaining bile acid homeostasis.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

9.73e-148138627412403
Pubmed

Mice lacking Ran binding protein 1 are viable and show male infertility.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

9.73e-148138621310149
Pubmed

The distribution of phosphorylated SR proteins and alternative splicing are regulated by RANBP2.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

9.73e-148138622262462
Pubmed

Zap70 and downstream RanBP2 are required for the exact timing of the meiotic cell cycle in oocytes.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

9.73e-148138628745977
Pubmed

Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIalpha.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

2.91e-139138618394993
Pubmed

Loss of Ranbp2 in motoneurons causes disruption of nucleocytoplasmic and chemokine signaling, proteostasis of hnRNPH3 and Mmp28, and development of amyotrophic lateral sclerosis-like syndromes.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

2.91e-139138628100513
Pubmed

Association of the kinesin-binding domain of RanBP2 to KIF5B and KIF5C determines mitochondria localization and function.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

2.91e-139138617887960
Pubmed

The docking of kinesins, KIF5B and KIF5C, to Ran-binding protein 2 (RanBP2) is mediated via a novel RanBP2 domain.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

2.91e-139138611553612
Pubmed

The zinc finger cluster domain of RanBP2 is a specific docking site for the nuclear export factor, exportin-1.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

2.91e-139138610601307
Pubmed

The cyclophilin-like domain mediates the association of Ran-binding protein 2 with subunits of the 19 S regulatory complex of the proteasome.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

2.91e-13913869733766
Pubmed

Impairments in age-dependent ubiquitin proteostasis and structural integrity of selective neurons by uncoupling Ran GTPase from the Ran-binding domain 3 of Ranbp2 and identification of novel mitochondrial isoforms of ubiquitin-conjugating enzyme E2I (ubc9) and Ranbp2.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

2.91e-139138628877029
Pubmed

The RanBP2/RanGAP1*SUMO1/Ubc9 SUMO E3 ligase is a disassembly machine for Crm1-dependent nuclear export complexes.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

7.25e-1310138627160050
Pubmed

Parkin ubiquitinates and promotes the degradation of RanBP2.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

7.25e-1310138616332688
Pubmed

Cyclophilin-related protein RanBP2 acts as chaperone for red/green opsin.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

7.25e-131013868857542
Pubmed

Ran-dependent docking of importin-beta to RanBP2/Nup358 filaments is essential for protein import and cell viability.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

7.25e-1310138621859863
Pubmed

RanBP2 modulates Cox11 and hexokinase I activities and haploinsufficiency of RanBP2 causes deficits in glucose metabolism.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

1.59e-1211138617069463
Pubmed

An Rtn4/Nogo-A-interacting micropeptide modulates synaptic plasticity with age.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

1.59e-1211138635771867
Pubmed

T-cell receptor (TCR) signaling promotes the assembly of RanBP2/RanGAP1-SUMO1/Ubc9 nuclear pore subcomplex via PKC-θ-mediated phosphorylation of RanGAP1.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

1.59e-1211138634110283
Pubmed

Ankyrin-G induces nucleoporin Nup358 to associate with the axon initial segment of neurons.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

5.87e-1213138631427429
Pubmed

Limited expression of nuclear pore membrane glycoprotein 210 in cell lines and tissues suggests cell-type specific nuclear pores in metazoans.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

1.70e-1115138614697343
Pubmed

Systematic identification of factors for provirus silencing in embryonic stem cells.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 MSH2 SBNO2 EIF3CL RGPD3 EIF3C ANAPC5

2.96e-111531381126365490
Pubmed

Terminal differentiation of cortical neurons rapidly remodels RanGAP-mediated nuclear transport system.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

2.48e-1022138627717094
Pubmed

Peering through the pore: nuclear pore complex structure, assembly, and function.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

8.70e-0938138612791264
Pubmed

Insights into specificity, redundancy and new cellular functions of C/EBPa and C/EBPb transcription factors through interactome network analysis.

RGPD4 RGPD2 RANBP2 RGPD8 MYO10 RGPD1 RGPD3

1.46e-0799138727746211
Pubmed

Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1.

RGPD4 RGPD2 RGPD8 BMS1 RGPD1 HAT1 RGPD3 RGPD5 RBM17

2.14e-07215138935973513
Pubmed

Identification of a novel Ran binding protein 2 related gene (RANBP2L1) and detection of a gene cluster on human chromosome 2q11-q12.

RANBP2 RGPD8 RGPD5

2.44e-07413839480752
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 EIF3CL NUFIP1 RMDN3 RTKN2 RGPD3 MSL3 ASPM CCAR1 EIF3C ATM ANAPC5 RGPD5 RBM17

7.98e-0711551381820360068
Pubmed

Interaction of Sox2 with RNA binding proteins in mouse embryonic stem cells.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 MSH2 RGPD3

1.21e-06135138731077711
Pubmed

A DNA break- and phosphorylation-dependent positive feedback loop promotes immunoglobulin class-switch recombination.

AICDA MSH2 ATM

1.21e-066138324097111
Pubmed

The ubiquitin ligase Uhrf2 is a master regulator of cholesterol biosynthesis and is essential for liver regeneration.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

1.27e-0686138637253089
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

DNAJB12 RANBP2 RPL38 RHBDF1 MINK1 BMS1 GTPBP10 RMDN3 STX18 ACAD11 RGPD3 ABCD3 CCAR1 UTP20 EIF3C ANAPC5 PREX1 MED13 AGAP1 SMG6

2.00e-0614971382031527615
Pubmed

A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 ZNF462 RGPD3

2.04e-06146138723892456
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

RGPD4 RGPD2 RANBP2 RPL38 RGPD8 RGPD1 ZDBF2 ZNF462 RGPD3 ABCD3

7.12e-064181381034709266
Pubmed

Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage.

RGPD4 RGPD2 RANBP2 RPL38 RGPD8 MYO1C RGPD1 MAGOHB LANCL1 ME2 EIF3CL RGPD3 EIF3C RGPD5

7.23e-068441381425963833
Pubmed

Oncogenic functions of protein kinase D2 and D3 in regulating multiple cancer-related pathways in breast cancer.

MYO10 LONRF1 ZDBF2 ACSBG2 UTY AGAP1

7.26e-06116138630652415
Pubmed

C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.

RGPD4 DNAJB12 RGPD2 RANBP2 RPL38 RGPD8 MYO1C VPS4A RGPD1 HAT1 SAMHD1 MSH2 EIF3CL RGPD3 ABCD3 EIF3C RGPD5

1.07e-0512571381737317656
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

UBR1 RANBP2 MYO1C MINK1 ISL2 EIF3CL MSL3 CCAR1 UTP20 EIF3C ATM ANAPC5 MED13

1.37e-057741381315302935
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

RANBP2 RPL38 MYO1C VPS4A BMS1 HAT1 LANCL1 APOB SAMHD1 MSH2 ME2 EIF3CL ABCD3 CCAR1 UTP20 EIF3C ATM DNAH5

1.46e-0514251381830948266
Pubmed

Individual substitution mutations in the AID C terminus that ablate IgH class switch recombination.

AICDA MSH2

1.56e-052138226267846
Pubmed

MSH2 Dysregulation Is Triggered by Proinflammatory Cytokine Stimulation and Is Associated with Liver Cancer Development.

AICDA MSH2

1.56e-052138227261510
Pubmed

Combined deficiency of MSH2 and Sμ region abolishes class switch recombination.

AICDA MSH2

1.56e-052138220812239
Pubmed

Control of cerebellar long-term potentiation by P-Rex-family guanine-nucleotide exchange factors and phosphoinositide 3-kinase.

PREX2 PREX1

1.56e-052138220694145
Pubmed

EIF3C Promotes Lung Cancer Tumorigenesis by Regulating the APP/HSPA1A/LMNB1 Axis.

EIF3CL EIF3C

1.56e-052138236157221
Pubmed

Loss of Ubr1 promotes aneuploidy and accelerates B-cell lymphomagenesis in TLX1/HOX11-transgenic mice.

UBR1 TLX1

1.56e-052138216862188
Pubmed

Apolipoprotein B and angiotensin-converting enzyme polymorphisms and aerobic interval training: randomized controlled trial in coronary artery disease patients.

APOB ACE

1.56e-052138229846435
Pubmed

Human splicing factor SPF45 (RBM17) confers broad multidrug resistance to anticancer drugs when overexpressed--a phenotype partially reversed by selective estrogen receptor modulators.

ESR2 RBM17

1.56e-052138216061639
Pubmed

P-Rex2 regulates Purkinje cell dendrite morphology and motor coordination.

PREX2 PREX1

1.56e-052138218334636
Pubmed

SAMHD1 enhances immunoglobulin hypermutation by promoting transversion mutation.

SAMHD1 MSH2

1.56e-052138229669924
Pubmed

P-Rex1 and P-Rex2 RacGEFs and cancer.

PREX2 PREX1

1.56e-052138228710285
Pubmed

Chemopreventive efficacy of raloxifene, bexarotene, and their combination on the progression of chemically induced colon adenomas to adenocarcinomas in rats.

ESR2 RXRA

1.56e-052138224080207
Pubmed

DNA Repair Gene Expression Levels as Indicators of Breast Cancer in the Breast Cancer Family Registry.

MSH2 ATM

1.56e-052138227466510
Pubmed

The mismatch repair pathway functions normally at a non-AID target in germinal center B cells.

AICDA MSH2

1.56e-052138221788338
Pubmed

Acidity and lipolysis by group V secreted phospholipase A(2) strongly increase the binding of apoB-100-containing lipoproteins to human aortic proteoglycans.

APOB PLA2G5

1.56e-052138222041135
Pubmed

The ER-Mitochondria Tethering Complex VAPB-PTPIP51 Regulates Autophagy.

KCNIP1 RMDN3

1.56e-052138228132811
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

DNAJB12 AMPD2 RANBP2 VPS4A DNAJC18 HAT1 SAMHD1 MSH2 OCRL RMDN3 STX18 ABCD3 UTP20 ANAPC5

2.45e-059421381431073040
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

RANBP2 HAT1 SAMHD1 MSH2 STX18 TK1 RGPD3 ABCD3 CCAR1 UTP20 EIF3C DNAH5

2.58e-057041381229955894
Pubmed

Proteomic and yeast 2-hybrid screens to identify PTEN binding partners.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 PREX2 RGPD3

3.51e-05226138737839992
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

RHBDF1 MYO10 LONRF1 ZZEF1 CHRM4 SBNO2 DIP2A PIK3C2B USP40 PCNX1 ZFYVE26 ARHGEF4 PREX1 MED13 SMG6

3.52e-0511051381535748872
Pubmed

Comprehensive identification of phosphorylation sites in postsynaptic density preparations.

RGPD4 RGPD2 RANBP2 RPL38 RGPD8 RGPD1 RGPD3

4.04e-05231138716452087
Pubmed

METTL3 protects METTL14 from STUB1-mediated degradation to maintain m6 A homeostasis.

UBR1 MSH2 EIF3CL MSL3 ABCD3 EIF3C SMG6

4.04e-05231138736597993
Pubmed

New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.

RGPD8 IFT172 HAT1 APOB PFKFB2 ZNF462 RGPD3 ADAMTS20 SMG6 RBM17

4.10e-055131381025798074
Pubmed

AID Phosphorylation Regulates Mismatch Repair-Dependent Class Switch Recombination and Affinity Maturation.

AICDA MSH2

4.68e-053138231757865
Pubmed

Uracil residues dependent on the deaminase AID in immunoglobulin gene variable and switch regions.

AICDA MSH2

4.68e-053138221151102
Pubmed

The role of angiotensin-converting enzyme and apolipoprotein-E gene polymorphisms on lipid compositions in newborn infants with intrauterine growth restriction.

APOB ACE

4.68e-053138215223114
Pubmed

Two levels of protection for the B cell genome during somatic hypermutation.

AICDA MSH2

4.68e-053138218273020
Pubmed

ATM deficiency promotes development of murine B-cell lymphomas that resemble diffuse large B-cell lymphoma in humans.

AICDA ATM

4.68e-053138226400962
Pubmed

DSB structure impacts DNA recombination leading to class switching and chromosomal translocations in human B cells.

AICDA MSH2

4.68e-053138230946744
Pubmed

FOXP3/HAT1 Axis Controls Treg Infiltration in the Tumor Microenvironment by Inducing CCR4 Expression in Breast Cancer.

HAT1 CCR4

4.68e-053138235222362
Pubmed

The in vivo pattern of AID targeting to immunoglobulin switch regions deduced from mutation spectra in msh2-/- ung-/- mice.

AICDA MSH2

4.68e-053138216894013
Pubmed

AID-targeting and hypermutation of non-immunoglobulin genes does not correlate with proximity to immunoglobulin genes in germinal center B cells.

AICDA MSH2

4.68e-053138222768095
Pubmed

Up-regulation of MSH2, XRCC1 and ATM genes in patients with type 2 diabetes and coronary artery disease.

MSH2 ATM

4.68e-053138226088318
Pubmed

Repair genes expression profile of MLH1, MSH2 and ATM in the normal oral mucosa of chronic smokers.

MSH2 ATM

4.68e-053138227693945
Pubmed

Population genetic analysis of the genes APOE, APOB(3'VNTR) and ACE in some black and Amerindian communities from Colombia.

APOB ACE

4.68e-053138211359065
Pubmed

Five polymorphisms in gene candidates for cardiovascular disease in Afro-Brazilian individuals.

APOB ACE

4.68e-053138215543563
Pubmed

Requirement of non-canonical activity of uracil DNA glycosylase for class switch recombination.

AICDA MSH2

4.68e-053138217090531
Pubmed

Transcription factor TLX1 controls retinoic acid signaling to ensure spleen development.

RXRA TLX1 STRA6

4.77e-0518138327214556
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

LONRF1 IFT172 ZNF423 CLIC6 NUFIP1 DIP2A STX18 SULF1 CCAR1 EIF3C ATM MGAT5B PREX1 MED13 SCAI AGAP1

5.35e-0512851381635914814
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

UBR1 MINK1 LANCL1 ZZEF1 SBNO2 TGFBI DIP2A ACAD11 ABCD3 CCAR1 ANAPC5

6.03e-056501381138777146
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

RGPD4 RGPD2 RANBP2 RGPD8 MYO1C RGPD1 DNAJC18 APOB RGPD3 ASPM PKHD1 CCAR1 ATM ARHGEF4 PREX1 MED13 RGPD5

6.05e-0514421381735575683
Pubmed

Structural and functional organization of TRAP220, the TRAP/mediator subunit that is targeted by nuclear receptors.

MED30 RXRA MED13

6.63e-0520138315340084
InteractionRGPD4 interactions

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3 RGPD5

8.55e-11221367int:RGPD4
InteractionRGPD2 interactions

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3 RGPD5

4.33e-10271367int:RGPD2
InteractionRGPD3 interactions

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3 RGPD5

2.74e-08471367int:RGPD3
InteractionRGPD1 interactions

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3 RGPD5

3.70e-08491367int:RGPD1
InteractionRGPD8 interactions

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3 RGPD5

6.74e-07741367int:RGPD8
InteractionRGPD5 interactions

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3 RGPD5

3.95e-06961367int:RGPD5
InteractionNPIPB6 interactions

RANBP2 RGPD8 RGPD1 RGPD5

5.64e-06181364int:NPIPB6
Cytoband2q13

RGPD8 RGPD3 TTL RGPD5

5.48e-056813842q13
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

RGPD4 RGPD2 SH3TC2 RANBP2 RGPD8 RGPD1 RGPD3 UTY RGPD5

1.22e-08115989769
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

MCF2 PREX2 ARHGEF4 PREX1

4.52e-0466984722
GeneFamilyAdhesion G protein-coupled receptors, subfamily G

ADGRG6 ADGRG2

6.00e-047982917
GeneFamilyAnoctamins

ANO4 ANO1

1.27e-0310982865
GeneFamilyCD molecules|I-set domain containing|Immunoglobulin like domain containing|Interleukin receptors|TIR domain containing

IL10RA IL1RAPL2 IL7R

1.52e-0342983602
GeneFamilyDNAJ (HSP40) heat shock proteins|C2 tensin-type domain containing

DNAJB12 DNAJC18 DNAJC27

2.37e-0349983584
CoexpressionGAUSSMANN_MLL_AF4_FUSION_TARGETS_B_UP

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

1.88e-08331386MM477
CoexpressionTABULA_MURIS_SENIS_TRACHEA_GRANULOCYTE_AGEING

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

9.92e-08431386MM3857
CoexpressionFOSTER_TOLERANT_MACROPHAGE_DN

RGPD4 RGPD2 RANBP2 RGPD8 MYO10 RGPD1 MFSD6L SAMHD1 PARP14 ADGRG6 RMDN3 RGPD3

3.47e-0643513812MM1221
CoexpressionNAKAYA_PBMC_FLUARIX_FLUVIRIN_AGE_18_50YO_CORRELATED_WITH_HAI_28DY_RESPONSE_AT_7DY_NEGATIVE

RGPD4 RGPD2 RANBP2 MED30 RGPD8 RGPD1 SAMHD1 SBNO2 ZSWIM9 RGPD3 CCAR1 RGPD5

8.28e-0647413812M40991
CoexpressionGSE360_T_GONDII_VS_B_MALAYI_HIGH_DOSE_MAC_UP

AVL9 MSH2 ZZEF1 ACE PTGER3 TLX1 TGFBI IL7R

1.10e-051991388M5254
CoexpressionMANNE_COVID19_COMBINED_COHORT_VS_HEALTHY_DONOR_PLATELETS_DN

MAGOHB HAT1 ACE PREX2 TGFBI ZNF117 LOXHD1 IL7R

2.57e-052241388M38981
CoexpressionHE_LIM_SUN_FETAL_LUNG_C7_SCHWANN_PRECURSOR_CELL

MYO10 MIS18A RUBCNL ITGA4 ADGRG6 RTKN2 TK1 ASPM

3.30e-052321388M45800
CoexpressionHE_LIM_SUN_FETAL_LUNG_C4_TREG_CELL

RGPD2 RGPD1 RTKN2 CCR4

5.80e-05401384M45776
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ISM1 ANO1 KCNIP1 PREX2 ADGRG6 FBXL7 SULF1 ASPM

1.23e-07186138877592a6397b44b2b59a4fc39d7224dd95343efe6
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ISM1 ANO1 KCNIP1 PREX2 ADGRG6 FBXL7 SULF1 ASPM

1.34e-0718813883139540a656c0436b2123ea50741ff8d00112165
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ISM1 ANO1 KCNIP1 PREX2 ZNF462 FBXL7 ASPM ADAMTS20

1.45e-0719013882f54da2bee411f8868348a4c37034184b8f58a89
ToppCellPCW_05-06-Epithelial-Epithelial_ciliated-epi_ciliated_(14)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

MCF2 MFSD6L APOB CLIC6 LRRC9 PKHD1 DNAH5

2.80e-0714013878abbd5dc799943b49cd0045d0da405c3f3d0db6b
ToppCellPCW_05-06-Epithelial-Epithelial_ciliated|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

MCF2 MFSD6L APOB CLIC6 LRRC9 PKHD1 DNAH5

2.80e-071401387e4689232c473d239b07a7fbcaaa3414fbd9badea
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_artery-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

ZNF423 ACE PREX2 PIK3C2B SULF1 PLA2G5 RGPD5

6.09e-071571387275a4c6fef1fff8da2bdc48e3924ad05c5e5cfc8
ToppCelldroplet-Marrow-BM-30m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SH3TC2 MYO10 MINK1 PFKFB2 ACE RXRA SCAI

7.52e-07162138775df7ff779a3b9159ba97d852da1f8df650b9ce5
ToppCell5'-Adult-Appendix-Hematopoietic-T_cells-CX3CR1+_CD8_Tmem|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IL10RA RGPD1 SAMHD1 ITGA4 DIP2A CFAP61 IL7R

1.31e-0617613876b06da40eb97ea2db09f3a769494738b3e5fe3fa
ToppCellControl|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ISM1 ITGA4 ACE LOXHD1 FBXL7 UTY IL7R

1.36e-061771387b8ff6940e31b749776e81ae4f5bbd577dba9749c
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANO1 KCNIP1 PREX2 ADGRG6 FBXL7 SULF1 ASPM

1.76e-061841387ae0a77e3e520a246b17776bb19503519636b02ee
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ESR2 ACE PREX2 ADGRG6 PIK3C2B SULF1 ATP13A3

2.34e-061921387285a9d332a1e07b94f222d4b518dd56928b9e075
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF423 PREX2 FBXL7 PIK3C2B SULF1 ATP13A3 PREX1

2.42e-0619313870b328f725f6feba263783eaca60c142e80df90f3
ToppCelllymphoid-T_cell-Regulatory_T_cell|World / Lineage, cell class and subclass

IL10RA RCBTB2 SAMHD1 ZNF462 RTKN2 CCR4 IL7R

2.68e-06196138742a4d706382be33d552ece1d0598d073857a8d4e
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

IL10RA RUBCNL SAMHD1 ITGA4 TGFBI PREX1 IL7R

2.77e-061971387c9b1f2ee7eb31a66af331c5aae29e1bbb5186f5a
ToppCellBronchial-NucSeq-Endothelial-Endothelia_vascular-VE_pulmonary_venous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ZNF423 DNAJC18 PREX2 ADGRG6 FBXL7 SULF1 MGAT5B

2.96e-0619913873a4deea6e11a0555d27497b7c9983350797aac69
ToppCellNeuronal-Inhibitory-iA-iA_2(LAMP5)-CA1-|Neuronal / cells hierarchy compared to all cells using T-Statistic

ANO1 KCNIP1 PREX2 ADGRG6 ZNF462 FBXL7 SULF1

3.06e-062001387ca5401b76ab014080914bf78042d368cf318effa
ToppCellNeuronal-Inhibitory-iA-iA_2(LAMP5)-CA1--L2-6|Neuronal / cells hierarchy compared to all cells using T-Statistic

ANO1 KCNIP1 PREX2 ADGRG6 ZNF462 FBXL7 SULF1

3.06e-06200138770c47d3bbe67d88c5b9dff99c33a603d25fa2ab0
ToppCellNeuronal-Inhibitory-iA-iA_2(LAMP5)-CA1|Neuronal / cells hierarchy compared to all cells using T-Statistic

ANO1 KCNIP1 PREX2 ADGRG6 ZNF462 FBXL7 SULF1

3.06e-06200138740286010bd17cf9e34ecd5440953b072ebfae208
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_3|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RGPD2 RGPD1 RTKN2 RGPD3 CCR4 IL7R

8.32e-0615313867480522a47e367f8facc4f5d599fbaf0b5ad4007
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_3|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

RGPD2 RGPD1 RTKN2 RGPD3 CCR4 IL7R

9.30e-06156138653ded973358e3e48054130131e959f0d1f4ef60f
ToppCell356C-Fibroblasts-Fibroblast-B_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ANO4 RGPD8 ANO1 KCNIP1 ADGRG6 MGAT5B

9.64e-061571386f6210be2362d833c6d869ff921188bfc85dda11d
ToppCell356C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ANO4 RGPD8 ANO1 KCNIP1 ADGRG6 MGAT5B

9.64e-06157138643a6b423fd70479822a564ff4225a1e4951ae5ed
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

UBR1 SH3TC2 ACE PREX2 SHQ1 ACAD11

1.28e-05165138662457b7b74c6eae42d91d65e7dc6df6bf8e061f7
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ACE PREX2 ADGRG6 LOXHD1 FBXL7 SULF1

1.32e-0516613867a45785a40b7425f97be67bab1c5ceb69b2bd85a
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ACE PREX2 ADGRG6 LOXHD1 FBXL7 SULF1

1.32e-051661386bbd382812f8a84a5d99888de2d7cca3a8b5e4695
ToppCellAdult-Endothelial-endothelial_cell_of_artery-D231|Adult / Lineage, Cell type, age group and donor

ZNF423 ACE PREX2 FBXL7 PIK3C2B SULF1

1.42e-051681386aca34c51758c65925ad24110294a72b2dea6db72
ToppCelldroplet-Marrow-nan-24m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL10RA MYO1C MINK1 ITGA4 ACE DIP2A

1.42e-051681386e979a4fbeb9f21048b47d69e6da75c57650697f2
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Epithelial-nan|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RUBCNL ITGA4 EPGN CHRM4 TGFBI IL7R

1.79e-0517513869a96794df049d8228fea57c1584c160191d36b56
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LONRF1 ACE PIK3C2B PCNX1 MGAT5B AGAP1

1.79e-051751386cf53a15bfb37b6019e7052ffdf594a9ac040900e
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANO1 KCNIP1 PREX2 ADGRG6 FBXL7 SULF1

1.97e-051781386f332c7a96844abecf05ca057480fbea9296688a2
ToppCellfacs-Lung-24m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ESR2 ACE ADGRG6 FBXL7 SULF1 ATP13A3

2.09e-051801386baa5825e6ce23a98d9c21d024a4b0ab8ba353d0c
ToppCellfacs-Lung-24m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ESR2 ACE ADGRG6 FBXL7 SULF1 ATP13A3

2.09e-0518013862d608b9394d28d19cfc85c6ac94003d5177c8a92
ToppCellfacs-Lung-24m-Endothelial-arterial_endothelial|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ESR2 ACE ADGRG6 FBXL7 SULF1 ATP13A3

2.09e-0518013860f9b27054358c4737eed06c8ea01987cccc3cb55
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ESR2 ACE PREX2 ADGRG6 SULF1 ATP13A3

2.16e-0518113864d7793026373cbcf04b15c77f95f1025d07d4c00
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ESR2 ZDBF2 ACE ADGRG6 SULF1 ATP13A3

2.23e-051821386c7f2d24697affa530b748ab32b1d40bdc1bdc20a
ToppCellpdx-Tumor_cells-T6|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

MYO10 ISM1 RGPD1 ZNF462 FBXL7 AGAP1

2.23e-0518213867b24a4f712e1ae1525e8f1c8ec4e1fc43489cbee
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ESR2 ZDBF2 ACE ADGRG6 SULF1 ATP13A3

2.23e-051821386d95635b74e8cd8bc00bfe40340806b59fb9bee43
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ESR2 ACE PREX2 ADGRG6 SULF1 ATP13A3

2.30e-0518313863427f3cbe6ea81709750e7dd3ff378f03ae65eab
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ESR2 ZDBF2 ACE ADGRG6 SULF1 ATP13A3

2.37e-051841386087666ba949b129c53d7ace40f9e543e3875a7de
ToppCelldroplet-Lung-nan-21m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ESR2 ZDBF2 ACE ADGRG6 SULF1 ATP13A3

2.52e-0518613865d0cd07b6b51e8ce9e1da949f757dc4575ec5752
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SAMHD1 ITGA4 PARP14 ACE PIK3C2B IL7R

2.59e-051871386f3397dbc23b6c2f24e2c1ba887d8f9aef3ee01a1
ToppCellpdx-Tumor_cells-T5|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

ISM1 RGPD1 ZNF462 FBXL7 STRA6 AGAP1

2.59e-0518713867e376831a11ee72ed87abcdac631ca46ae29c250
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-lymphocytic-T_lymphocytic-effector_CD4-positive,_alpha-beta_T_cell|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

IL10RA RANBP2 SAMHD1 ACE EIF3CL PCNX1

2.59e-051871386e61c1755531469dd3850c9740474b5ad4e0499c1
ToppCellControl-Endothelial_cells-Arterial_endothelial_cells|Control / group, cell type (main and fine annotations)

ZNF423 PREX2 ADGRG6 FBXL7 PIK3C2B SULF1

2.59e-05187138681affaab3fe3e1daea45ada6445e906ddd33950e
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANO1 KCNIP1 PREX2 ADGRG6 FBXL7 SULF1

2.67e-0518813868268574584e5fb869a6cb8bbd7135cd7454a6a25
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

RANBP2 PARP14 PCNX1 ATP13A3 MED13 SMG6

2.67e-051881386ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellP07-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ESR2 ACE PREX2 ADGRG6 SULF1 ATP13A3

2.67e-0518813865bc1537e079c7435196c163bff5f639ea392a33a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF423 ANO1 MCF2 ISL2 KCNIP1 STX18

2.67e-05188138632f22a4d8cb98fd8b8fa0fbf28ef9266d711d081
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ANO4 ISM1 ANO1 ADGRG6 TGFBI SMC1B

2.67e-0518813864d1e5f85342ae550086609d7680e32730b78b5d2
ToppCellhuman_hepatoblastoma-Tumor_cells-T5|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

MYO10 ZNF462 FBXL7 STRA6 MGAT5B AGAP1

2.67e-051881386b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCellMesenchymal-myofibroblast_cell|World / Lineage, Cell type, age group and donor

ANO4 ISM1 ANO1 ADGRG6 TGFBI FBXL7

2.75e-05189138644e37f88137bb249933eb615235b2cf2ae7f3925
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ESR2 ACE ADGRG6 PIK3C2B SULF1 ATP13A3

2.75e-0518913869da012fdfa9a8d488cab710a463a1d70e89f990c
ToppCell3'_v3-blood-Lymphocytic_T_CD8|blood / Manually curated celltypes from each tissue

RPL38 ITGA4 DIP2A ATM UTY IL7R

2.84e-0519013865dca8654964c41580fa3b094579fe7cb296d406f
ToppCelldroplet-Marrow-nan-21m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MIS18A MAGOHB ME2 TGFBI TMEM192 STARD3NL

2.84e-0519013866c6d3259e23ec90c08756f500ae8a7aff8b8a5b3
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ESR2 ACE PREX2 ADGRG6 SULF1 ATP13A3

2.84e-051901386d87b9e9ca863270a9c7f61674271a6440c97d1f4
ToppCellwk_15-18-Hematologic_Lymphocytic-T_&_ILC-Treg|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

IL10RA RGPD2 RGPD1 RTKN2 CCR4 IL7R

2.84e-051901386fe6fecdf2123f3a4fb20e7535472d562b1a74fb4
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-AEC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ZNF423 PREX2 ADGRG6 FBXL7 PIK3C2B SULF1

2.92e-05191138650601ef0a5a8f2c2120922989e08e85bf2d9b4ab
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PREX2 FBXL7 PIK3C2B SULF1 ATP13A3 PREX1

2.92e-051911386b2c86cde341fe350143658c8a8a4a9edbce3f19b
ToppCellControl-Endothelial-VE_Arterial|Endothelial / Disease state, Lineage and Cell class

SH3TC2 PREX2 PIK3C2B SULF1 PLA2G5 ATP13A3

3.01e-0519213867e89b9125e8b85f6be85eeccef5c8644647ab0e1
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)

RGPD2 RANBP2 MYO1C ZDBF2 UTY IL7R

3.01e-051921386aee6522d25e012231cdb905ce047295cb64d6e82
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ANO4 ANO1 KCNIP1 RTKN2 TK1 ASPM

3.19e-051941386590a9d4f054e6a3685daf752c9354650fcc7d18a
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

IL10RA SAMHD1 ITGA4 ATM PREX1 IL7R

3.19e-0519413864dfc890bacf133cfb6ec7c8b73f084f2491cf78e
ToppCellsevere-Lymphocytic-CD4_T_cells_3|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

IL10RA RPL38 ZDBF2 RTKN2 CCR4 IL7R

3.28e-05195138690136f65e3e72cf2b2e0a13b48a7c9d60628b396
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ZNF423 PREX2 ADGRG6 FBXL7 PIK3C2B SULF1

3.28e-051951386023e3c97dd3696d74f002ff8da0c04d876c82aef
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ACE PREX2 PIK3C2B SULF1 PLA2G5 ATP13A3

3.38e-051961386cf7f384c1771274e766bab03ecc3dfbd13f2df60
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ANO4 ITGA4 TGFBI SULF1 STARD3NL DNAH5

3.47e-0519713862e3d64648a1e4f01b9256a96b94b8a640ee1824c
ToppCelllymphoid-T_cell-Regulatory_T_cell|lymphoid / Lineage, cell class and subclass

IL10RA RCBTB2 SAMHD1 ZNF462 RTKN2 CCR4

3.47e-05197138673d5dcf076caae60ea32258b4e9dcac8979a661e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IL10RA RUBCNL SAMHD1 ITGA4 PREX1 IL7R

3.47e-0519713860523aec9713ae21e6b879aa98e07fa2576610d5f
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IL10RA RUBCNL SAMHD1 ITGA4 TGFBI PREX1

3.47e-051971386d95565652ca318a2298d6918d54ba6367e9560f4
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IL10RA RUBCNL SAMHD1 ITGA4 PREX1 IL7R

3.47e-05197138661ef3f417767c3f5296a26399da63e3e4f58faf8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IL10RA RUBCNL SAMHD1 ITGA4 TGFBI PREX1

3.57e-05198138696883ad8e189a46ed5b7eaafc0543e53682d26ed
ToppCelllymphoid-T_cell-Regulatory_T_cell|T_cell / Lineage, cell class and subclass

IL10RA RCBTB2 SAMHD1 ZNF462 RTKN2 CCR4

3.57e-0519813866773c6043ef4a3d9e9700330b6386431ee66abdc
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IL10RA RUBCNL SAMHD1 ITGA4 TGFBI PREX1

3.67e-05199138604adf46975aa4194ea40c7480f8a517def5d929c
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PARP14 DIP2A ATM UTY SMG6 RGPD5

3.67e-051991386f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellCaecum-(1)_T_cell-(16)_Tfh|Caecum / shred on region, Cell_type, and subtype

ACE ZSCAN20 RGPD3 CCR4 ATM IL7R

3.67e-051991386d07d77ae426dd1164d80d7031f14befa0369d3e5
ToppCellCaecum-T_cell-Tfh|Caecum / Region, Cell class and subclass

ACE ZSCAN20 RGPD3 CCR4 ATM IL7R

3.67e-051991386fb40f37d842f170ed101dfa3bffdb8f3b2c94f19
ToppCell(1)_T_cell-(16)_Tfh|(1)_T_cell / shred on Cell_type and subtype

RPL38 RGPD1 RCBTB2 EPGN SBNO2 ATM

3.78e-0520013863b28137e8e69b98fde9f6ab8320cb4d1c3543ef9
ToppCellParenchymal-10x5prime-Endothelial-Endothelia_vascular-VE_pulmonary_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ACE PREX2 ADGRG6 PIK3C2B SULF1 PLA2G5

3.78e-052001386ac6b8bc9998d303f788511b8f111e682ea9f3df8
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Activated_Gen_Cap|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

SAMHD1 PARP14 ACE PREX2 PIK3C2B IL7R

3.78e-0520013863585484c7e24e941708bee471ca607d8ccee74e6
ToppCellVE-CD4-CD8_2|VE / Condition, Cell_class and T cell subcluster

MYO10 MCF2 ELL3 LRRC9 IL7R

3.92e-0512213856745035feaf807b6a6b9537ac9d5ee0e000196eb
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c02-AQP3|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SAMHD1 SBNO2 RTKN2 DNAH5 IL7R

5.31e-051301385c63f402d6ab71c2fcef12174b3139e55a727266c
ToppCellMild/Remission-B_naive-1|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

RGPD4 RUBCNL EIF3CL PCNX1 EIF3C

8.35e-051431385bd3f5fbd4e9e4dc414682db5607494f3ce988deb
ToppCell10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8|bone_marrow / Manually curated celltypes from each tissue

RANBP2 PCNX1 ATM UTY SMG6

1.26e-0415613851545169694f686d28648a68b552c2ae606599d66
ToppCelldroplet-Liver-LIVER_HEP-30m-Myeloid-myeloid_leukocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL10RA ITGA4 ACE TGFBI ASPM

1.33e-04158138591d265e95156f16459924d3e4dd11c180e164eee
ToppCell10x5'v1-week_12-13-Hematopoietic-HSC/MPP_and_pro-HSC/MPP|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

LEKR1 LANCL1 MFSD6L PREX2 LRRC9

1.46e-04161138546b5d80d2d521fb69752aba4c10383e715a32002
ToppCell3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SH3TC2 EIF3CL TK1 ASPM ZNF681

1.46e-0416113852165897924c790fec43502283f1df221c56c1e9f
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-CytoT_GZMK+-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

ESR2 ITGA4 ZSCAN20 ATM UTY

1.50e-04162138519395bdb282b4a2d88cd33191af12c24a88c3d16
ToppCell10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8|blood / Manually curated celltypes from each tissue

RANBP2 PCNX1 ATM UTY IL7R

1.50e-041621385b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCelldroplet-Liver-LIVER_HEP-30m-Myeloid-macrophage/monocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL10RA ITGA4 ACE TGFBI ASPM

1.50e-04162138593bd29c52846c3156b8b0d2e39c552373efdfe93
ToppCellnormal-na-Lymphocytic_T-T4_reg-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

RGPD2 RTKN2 ADGRG2 CCR4 UTY

1.54e-04163138543887e7687fc6367efac0c1f56a9534b06f47b7f
ToppCellfacs-Lung-EPCAM-24m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL10RA RUBCNL SAMHD1 ITGA4 EPGN

1.59e-04164138515d52666e5150e7c34b1f641a937fb2d5e8aaf8a
ToppCellfacs-Lung-EPCAM-24m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL10RA RUBCNL SAMHD1 ITGA4 EPGN

1.59e-041641385d622f0d8d8bad48dfdf160ec63c545df192637a9
ToppCelldroplet-Lung-nan-18m-Myeloid-intermediate_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL10RA SAMHD1 ITGA4 ACE TGFBI

1.63e-041651385e32697321cef424c2ad4e11ee9da3e510d5ce505
ToppCelldroplet-Lung-nan-18m-Myeloid-Intermediate_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL10RA SAMHD1 ITGA4 ACE TGFBI

1.63e-0416513850fbdd043e11aa8dbff4cd3a4da1b2feb49878a09
ToppCellmild-Lymphocytic-CD4_T_cells_3|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

IL10RA ZDBF2 SAMHD1 RTKN2 CCR4

1.68e-041661385f8f8423423d72f0ea0266b59126abb27beb23094
ToppCell367C-Fibroblasts-Fibroblast-G|367C / Donor, Lineage, Cell class and subclass (all cells)

ANO4 APOB ACAD11 ADGRG2 PLA2G5

1.78e-0416813858c95093b1ea45826f62893edd3c410fe53b563a4
ToppCelldroplet-Lung-18m-Hematologic-myeloid-intermediate_monocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IL10RA SAMHD1 ITGA4 ACE TGFBI

1.78e-04168138500cff4698db14e03ca1d1b409e5ed1ad23b12615
ToppCell367C-Fibroblasts-Fibroblast-G-|367C / Donor, Lineage, Cell class and subclass (all cells)

ANO4 APOB ACAD11 ADGRG2 PLA2G5

1.78e-041681385b8c65542a0701ae31f49d332d87a64578e24b4e3
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Lgr5+_amplifying_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLIC6 OCRL UTP20 SLC5A8 MED13

1.78e-041681385d69452e2cfeb74023b5cf3d09064d7dcad0008ec
ToppCellfacs-Liver-Non-hepatocytes-24m-Myeloid-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL10RA SAMHD1 ITGA4 ACE TGFBI

1.83e-0416913852d3618f78484bd3508b7bdae3a0d0183cdae5057
Diseasetriglyceride change measurement, low density lipoprotein cholesterol measurement

UTP20 SLC5A8

1.99e-0521322EFO_0004611, EFO_0007681
DiseaseCoronary heart disease

ESR2 APOB ACE

1.65e-04241323C0010068
Diseaseadrenoleukodystrophy (implicated_via_orthology)

ABCD3 ACSBG2

4.11e-0471322DOID:10588 (implicated_via_orthology)
DiseaseAutistic behavior

ZNF462 MED13

5.46e-0481322C0856975
Diseaseinterleukin 2 measurement

ANO4 LEKR1 SLC5A8

8.24e-04411323EFO_0008331
Diseaselung non-small cell carcinoma (is_marker_for)

MSH2 PREX2 TK1 ATM IL7R

1.00e-031691325DOID:3908 (is_marker_for)
Diseaseautosomal recessive polycystic kidney disease (biomarker_via_orthology)

ACE PKHD1

1.06e-03111322DOID:0110861 (biomarker_via_orthology)
DiseaseCeliac Disease

APOB ACE CCR4

1.23e-03471323C0007570
Diseasecannabis dependence measurement

DIP2A PKHD1 CCAR1

1.31e-03481323EFO_0008457
Diseasealcohol and nicotine codependence

RGPD2 RGPD1

1.50e-03131322EFO_0004776
Diseaseinfant head circumference

LEKR1 PREX1

2.01e-03151322EFO_0004577
Diseasesmoking behavior, BMI-adjusted waist circumference

ZNF423 LEKR1 ADGRG6 PREX1

2.24e-031221324EFO_0004318, EFO_0007789
Diseaseautosomal recessive polycystic kidney disease (implicated_via_orthology)

ACE PKHD1

2.29e-03161322DOID:0110861 (implicated_via_orthology)
Diseaselymphocyte count

SH3TC2 MED30 MINK1 SAMHD1 ITGA4 PREX2 SBNO2 NUFIP1 DIP2A ATM PREX1 IL7R AGAP1 SMG6 RBM17

2.35e-03146413215EFO_0004587
Diseaserenovascular hypertension (biomarker_via_orthology)

ACE PTGER3

3.23e-03191322DOID:1591 (biomarker_via_orthology)
DiseaseColorectal cancer, hereditary nonpolyposis, type 1

MSH2 ATM

3.23e-03191322C2936783
Diseasehemifacial microsomia

ANO1 AGAP1

3.23e-03191322MONDO_0015398
DiseaseSclerocystic Ovaries

PTGER3 ZSWIM9 ASPM MGAT5B

4.06e-031441324C1136382
DiseasePolycystic Ovary Syndrome

PTGER3 ZSWIM9 ASPM MGAT5B

4.06e-031441324C0032460
Diseaseotitis media (implicated_via_orthology)

RPL38 DNAH5

4.33e-03221322DOID:10754 (implicated_via_orthology)
DiseaseColorectal Carcinoma

ESR2 HAT1 APOB MSH2 PREX2 TK1 ABCD3 PKHD1 CCAR1

4.41e-037021329C0009402

Protein segments in the cluster

PeptideGeneStartEntry
KKTFRHLLLCQYRNI

CHRM4

461

P08173
YYEACRKAAKSLIKL

ACSBG2

86

Q5FVE4
KKLRVFVYRNSLCIE

TGFBI

461

Q15582
IAADCKRVTVLKYFL

SMG6

1121

Q86US8
LKRIECYKVTYRPLD

PFKFB2

191

O60825
LVIFYCYIRKRCLKL

EPGN

126

Q6UW88
KRKAISRELYEYCIK

BUD31

66

P41223
KEILRLGFKSCLYYR

CFAP61

576

Q8NHU2
YREEKRRCEYLHQKL

ELL3

366

Q9HB65
RKLSNDLKRCTYYET

AGAP1

196

Q9UPQ3
FYNRKDFRIKQCTRV

ACE

366

P12821
NKVVLRESCFYRKLT

CCAR1

966

Q8IX12
IVYAQRRLKKIGIFC

ATP13A3

466

Q9H7F0
KVFNTYIRRYILKFC

ADGRG6

961

Q86SQ4
VFNTYIRKYILKFCI

ADGRG2

726

Q8IZP9
AKGRRETYLCYVVKR

AICDA

21

Q9GZX7
IYRCQKAFVKALEQR

ARHGEF4

336

Q9NR80
EAQRLSLRFAKCTKY

BTBD11

146

A6QL63
YKVLTRNIEYIAKCL

CHRNA9

421

Q9UGM1
FRKYILQLFKTCRGL

CCR4

311

P51679
IKSFCYRRLQYLSSK

AMPD2

371

Q01433
KCRIDYILVYRKSNP

ANO4

116

Q32M45
CSRIAIKKYLRAGYD

CLIC6

466

Q96NY7
RTNIKCDRKVSLYGY

BMS1

271

Q14692
CYRSKKIAAQKREEY

ASPM

1711

Q8IZT6
YLNIKGRIIKIYCAD

ADAMTS20

1731

P59510
CERATQRIAFKKKLY

ACAD11

651

Q709F0
LATFYRENRLKKLCQ

RCBTB2

466

O95199
ECKNYLRKTRDYLIK

RANBP2

706

P49792
VEPKFVKRLRYCEYL

RUBCNL

441

Q9H714
ECRNYLTKTRDYLIK

RGPD5

706

Q99666
ECRNYLTKTRDYLIK

RGPD8

706

O14715
KRQLEDDCYYINRRK

MSL3P1

106

P0C860
ECRNLEKLYLYFNKI

LRRC9

96

Q6ZRR7
CKERIRDVVYFQARL

ANAPC5

706

Q9UJX4
IKLYVRCVFITDDFR

HSP90B2P

66

Q58FF3
RFRELKLQHKEYLCV

ESR2

386

Q92731
LIQAYKVFREEKYLC

LANCL1

286

O43813
ELKIKYRQSYIFRLC

LEKR1

116

Q6ZMV7
CIIKRYCEKRFVSKY

DNAJC27

31

Q9NZQ0
KEYLADRRYCVTQLL

LONRF1

521

Q17RB8
YLCTNKREQKQFFER

LOXHD1

1136

Q8IVV2
SFKKYRCRIRVIDTF

MGAT5B

381

Q3V5L5
CAFLAKSYRKRRALL

MFSD6L

66

Q8IWD5
RRYLSFRVIKVNKEC

PCNX1

1931

Q96RV3
KILLRKFCQIRYHTN

PTGER3

351

P43115
KKQLEDDCYYINRRK

MSL3

181

Q8N5Y2
DDCYYINRRKRLVKL

MSL3

186

Q8N5Y2
FLARKQYRKVLYCVV

MYO10

756

Q9HD67
KCLNFRKLQEIYFIE

IL7R

81

P16871
AYCLALQLYVRRRKK

IL10RA

251

Q13651
CVKRKQRYEVDYNLE

ANO1

706

Q5XXA6
RRFQIAQYKCLVIKY

TK1

41

P04183
AQYKCLVIKYAKDTR

TK1

46

P04183
SVLFRKLRLVYDKCN

MED30

86

Q96HR3
KRELQVLYRGFKNEC

KCNIP1

61

Q9NZI2
CLRRSIYKNKFELTY

IFT172

316

Q9UG01
YIQYCRKFDIDIRLQ

PIK3C2B

446

O00750
DRKLVYCLKRNLRSY

PLA2G5

111

P39877
VQLSLCLAEKYKYRS

PARP14

901

Q460N5
EECKNYLRKTRGYLI

RGPD3

706

A6NKT7
LCKYIYAKDRTDRIR

EIF3C

551

Q99613
RLCKYIYAKDRTDRI

EIF3CL

551

B5ME19
FRFLQKYIQKETECL

ATM

61

Q13315
CKLDFREIQIYKKLR

APOB

3761

P04114
SYVKLRDFVLVKLCQ

HAT1

281

O14929
CVLFRKYGNFIDKLR

GTPBP10

6

A4D1E9
VAKYCSKLRYLNARG

FBXL7

371

Q9UJT9
ISCYRQIEAKALKVR

AVL9

91

Q8NBF6
AVKRVKQCKDYYEIL

DNAJB12

101

Q9NXW2
YRVKQRKLDYKCFSE

DUXB

66

A0A1W2PPF3
LFLYEKAIVFCKRRV

MCF2

726

P10911
LRKYREKYCTFNDDI

ME2

266

P23368
IVRFLSKTDKRLLYC

ITGA4

876

P13612
LLGVQRIKKCRNYYE

DNAJC18

71

Q9H819
RIKKCRNYYEILGVS

DNAJC18

76

Q9H819
YDCIFKRRLDYDQKL

C5orf49

56

A4QMS7
SFERCLKTYAIKRAA

EML5

931

Q05BV3
VCFYKARAALVKSRD

DIP2A

596

Q14689
ALREKVYASLEAYCK

RXRA

391

P19793
EKLEIYKPTARYCIR

ISM1

356

B1AKI9
YYFRVTCKEEKVLRN

MSH2

521

P43246
ARKFFTLYKLCEEQL

DNAH5

2131

Q8TE73
EECKNYLRKTRDYLI

RGPD1

696

P0DJD0
RDGKTYCKRDYVRLF

ISL2

71

Q96A47
IRKYKKRFNSEILCA

MINK1

1011

Q8N4C8
LRVFYYLVQDLKCLV

MAGOHB

121

Q96A72
AYRCFKERRVTKAYL

RPUSD1

86

Q9UJJ7
NKERSRRYAIFCLFK

RTKN2

121

Q8IZC4
RILKKCYRGRFQLIE

RTP3

121

Q9BQQ7
RVQCRQVFLKYILDY

UTP20

2261

O75691
YCLLKILKQYQTLRE

UTY

1241

O14607
EECKNYLRKTRGYLI

RGPD4

706

Q7Z3J3
RVYISKCYRELGKNS

RMDN3

421

Q96TC7
RVYCKKVDRKSLYAA

SAMHD1

551

Q9Y3Z3
NVKFKVRCSRYLYTL

RPL38

31

P63173
CKNYLRKTRDYLIKI

RGPD2

706

P0DJD1
NYTCELKYEGKLVRR

IL1RAPL2

211

Q9NP60
ELELYRKQCNARKKY

HMGB4

156

Q8WW32
SFGKFDLYRKRCQII

RHBDF1

791

Q96CC6
ERKRQLKKQYYFDCT

SMYD1

261

Q8NB12
FFLFDNLLVYCKRKS

PREX1

291

Q8TCU6
FVNKSYLLDKRACRQ

SHQ1

256

Q6PI26
YEYLELRFNKCVRLC

SLC5A8

116

Q8N695
QRFFKYLCIAAKVRR

SBNO2

541

Q9Y2G9
KVYYRLGRLTFCQLK

SH3TC2

1211

Q8TF17
NLRLKNFKVYSCRDF

PKHD1

2411

P08F94
FSKLKLYAQVCRYDL

MED13

1446

Q9UHV7
FIYCLRNREVKEALK

OR6B1

286

O95007
IFARKDQCRYIRDIA

OCRL

326

Q01968
YSEEYLRNLLCRKKL

STRA6

246

Q9BX79
KLCFRVRLTKYLYEE

ABCD3

151

P28288
DVCDKVFIRKRYLAR

ZNF525

246

Q8N782
CLLIYTVKIRRFNKA

TMEM192

186

Q8IY95
LKYSYVRLVCKDVRA

ZSWIM9

71

Q86XI8
CRYRVKNLLRNYRKA

ZSCAN20

376

P17040
LQCVRYIIKKDFFGL

NUFIP1

471

Q9UHK0
VYRCTPKNLDYKRDL

MIS18A

151

Q9NYP9
EQVKKRRYDLFTQCF

SMC1B

1056

Q8NDV3
YLKRVCKLYSEQRAI

STX18

141

Q9P2W9
FRFKVLILAYAVCRL

STARD3NL

106

O95772
VVKACFYNLDKFRVL

RBM17

381

Q96I25
DNDIRFICKYKRNIF

ZDBF2

2036

Q9HCK1
DTYIKERKLCAYPRL

TEX264

156

Q9Y6I9
ELQIREKNERYYCVL

UBR1

216

Q8IWV7
VKKLRYYARFIVVCL

SCAI

176

Q8N9R8
FLFDNLLVYCKRKHR

PREX2

266

Q70Z35
AVRYERKKRNICYDP

TRIM60

316

Q495X7
LQICELEKRFHRQKY

TLX1

211

P31314
IIYTRDKLYKREECS

ZNF681

246

Q96N22
NCKSKRAVRDYLFRV

ZZEF1

2596

O43149
FQKVTLRRYRKCGYE

ZNF117

31

Q03924
KFCVRYFRSKNLLIE

ZNF462

111

Q96JM2
ANLYGYIRCKVRSRK

TVP23B

166

Q9NYZ1
QFCDKSFIRLSYLKR

ZNF423

141

Q2M1K9
KECGKLFNRIAYLAR

ZNF766

246

Q5HY98
PKYERVKELCQQARY

SULF1

436

Q8IWU6
LLRFNFDFVKCERYK

USP40

246

Q9NVE5
LVNYYRGADKLCRKA

TTL

61

Q8NG68
YCRAARQLVEKEKYS

ZFYVE26

2406

Q68DK2
YQKCYSIEQPLRRDK

ZNF134

96

P52741
VQYLDRAEKLKDYLR

VPS4A

61

Q9UN37
CYDLLVRKKRLIVLF

JKAMP

241

Q9P055
RKYEAFLQRYKSLCP

MYO1C

666

O00159