Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	molecular adaptor activity	CUL1 KDM3A TRIM25 RBBP8 GPS2 CGAS TRIM24 AXIN2 KMT2C TLE1 NFKB1 SYNE2 ITSN2 VAMP7 ZNF721 EXOC7 AKAP1 ZDHHC11 CNOT1	1.12e-04	1356	108	19	GO:0060090
GeneOntologyCellularComponent	centrosome	CENPF CNTRL CEP290 SLC1A4 AXIN2 SPDL1 CCDC88C HOOK3 KIF15 TUBGCP3 ITSN2 TNKS PKN2 EXOC7	3.10e-05	770	105	14	GO:0005813
GeneOntologyCellularComponent	spindle pole	CENPF CNTRL SPDL1 KIF15 TUBGCP3 TNKS MTCL1	7.96e-05	205	105	7	GO:0000922
GeneOntologyCellularComponent	microtubule organizing center	CENPF CNTRL CEP290 SLC1A4 AXIN2 SPDL1 CCDC88C HOOK3 KIF15 TUBGCP3 ITSN2 TNKS PKN2 EXOC7	2.02e-04	919	105	14	GO:0005815
Domain	-	ZFAT ZNF486 ZNF875 ZNF549 ZNF235 ZNF865 ZNF711 ZNF462 ZNF721 ZNF84 ZNF85 ZNF649 ZNF791 ZNF292 ZNF304 ZNF445	8.07e-07	679	102	16	3.30.160.60
Domain	ZINC_FINGER_C2H2_2	ZFAT ZNF486 ZNF875 ZNF549 ZNF385A ZNF235 ZNF865 ZNF711 ZNF462 ZNF721 ZNF84 ZNF85 ZNF649 ZNF791 ZNF292 ZNF304 ZNF445	9.46e-07	775	102	17	PS50157
Domain	ZINC_FINGER_C2H2_1	ZFAT ZNF486 ZNF875 ZNF549 ZNF385A ZNF235 ZNF865 ZNF711 ZNF462 ZNF721 ZNF84 ZNF85 ZNF649 ZNF791 ZNF292 ZNF304 ZNF445	9.80e-07	777	102	17	PS00028
Domain	zf-C2H2	ZFAT ZNF486 ZNF875 ZNF549 ZNF235 ZNF865 ZNF711 ZNF462 ZNF721 ZNF84 ZNF85 ZNF649 ZNF791 ZNF292 ZNF304 ZNF445	1.05e-06	693	102	16	PF00096
Domain	Znf_C2H2/integrase_DNA-bd	ZFAT ZNF486 ZNF875 ZNF549 ZNF235 ZNF865 ZNF711 ZNF462 ZNF721 ZNF84 ZNF85 ZNF649 ZNF791 ZNF292 ZNF304 ZNF445	1.07e-06	694	102	16	IPR013087
Domain	Znf_C2H2-like	ZFAT ZNF486 ZNF875 ZNF549 ZNF385A ZNF235 ZNF865 ZNF711 ZNF462 ZNF721 ZNF84 ZNF85 ZNF649 ZNF791 ZNF292 ZNF304 ZNF445	1.36e-06	796	102	17	IPR015880
Domain	Znf_C2H2	ZFAT ZNF486 ZNF875 ZNF549 ZNF385A ZNF235 ZNF865 ZNF711 ZNF462 ZNF721 ZNF84 ZNF85 ZNF649 ZNF791 ZNF292 ZNF304 ZNF445	1.59e-06	805	102	17	IPR007087
Domain	ZnF_C2H2	ZFAT ZNF486 ZNF875 ZNF549 ZNF385A ZNF235 ZNF865 ZNF711 ZNF462 ZNF721 ZNF84 ZNF85 ZNF649 ZNF791 ZNF292 ZNF304 ZNF445	1.67e-06	808	102	17	SM00355
Domain	KRAB	ZNF486 ZNF875 ZNF549 ZNF235 ZNF84 ZNF85 ZNF649 ZNF791 ZNF304 ZNF445	2.63e-05	358	102	10	PS50805
Domain	KRAB	ZNF486 ZNF875 ZNF549 ZNF235 ZNF84 ZNF85 ZNF649 ZNF791 ZNF304 ZNF445	2.63e-05	358	102	10	PF01352
Domain	KRAB	ZNF486 ZNF875 ZNF549 ZNF235 ZNF84 ZNF85 ZNF649 ZNF791 ZNF304 ZNF445	3.40e-05	369	102	10	SM00349
Domain	KRAB	ZNF486 ZNF875 ZNF549 ZNF235 ZNF84 ZNF85 ZNF649 ZNF791 ZNF304 ZNF445	3.48e-05	370	102	10	IPR001909
Domain	zf-C2H2_6	ZNF486 ZNF549 ZNF865 ZNF721 ZNF84 ZNF85 ZNF649 ZNF791 ZNF445	5.57e-05	314	102	9	PF13912
Domain	ATP-guanido_PTrfase	CENPF CKM	2.92e-04	5	102	2	IPR000749
Domain	SMC	SMC2 SMC1B	2.92e-04	5	102	2	IPR024704
Domain	SMC_hinge	SMC2 SMC1B	4.37e-04	6	102	2	PF06470
Domain	SMC_hinge	SMC2 SMC1B	4.37e-04	6	102	2	SM00968
Domain	HOOK	CCDC88C HOOK3	4.37e-04	6	102	2	PF05622
Domain	Hook-related_fam	CCDC88C HOOK3	4.37e-04	6	102	2	IPR008636
Domain	SMC_hinge	SMC2 SMC1B	4.37e-04	6	102	2	IPR010935
Domain	RecF/RecN/SMC_N	SMC2 SMC1B	8.09e-04	8	102	2	IPR003395
Domain	SMC_N	SMC2 SMC1B	8.09e-04	8	102	2	PF02463
Domain	Cullin_repeat-like_dom	CUL1 EXOC7	1.88e-03	12	102	2	IPR016159
Domain	Spectrin_alpha_SH3	SH3GL3 ITSN2	2.96e-03	15	102	2	IPR013315
Domain	Quino_amine_DH_bsu	WDR36 LRRK1	6.35e-03	22	102	2	IPR011044
Pubmed	TLR4/NF-κB-responsive microRNAs and their potential target genes: a mouse model of skeletal muscle ischemia-reperfusion injury.	NFKB1 TLR4 DDX21	5.95e-07	6	109	3	25692136
Pubmed	Defining the membrane proteome of NK cells.	KDM3A GALNT2 CNTRL CEP290 MSH2 SLC1A4 KIDINS220 KIF15 NUP210 TUBGCP3 GOLIM4 EXOC7 DDX21 AKAP1 YME1L1 CNOT1	7.52e-07	1168	109	16	19946888
Pubmed	Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.	ZNF486 ZNF235 ZNF721 ZNF84 ZNF649 ZNF791 ZNF445	1.75e-06	181	109	7	37372979
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	CENPF RBBP8 TRIM24 SPDL1 ZNF462 KIF15 TLE1 AKAP1 CNOT1	7.10e-06	418	109	9	34709266
Pubmed	The protective effect of cinnamaldehyde on lipopolysaccharide induced acute lung injury in mice.	NFKB1 TLR4	9.73e-06	2	109	2	28886315
Pubmed	Toll-like receptor 4 promotes high glucose-induced catabolic and inflammatory responses in chondrocytes in an NF-κB-dependent manner.	NFKB1 TLR4	9.73e-06	2	109	2	30953645
Pubmed	Human intersectin 2 (ITSN2) binds to Eps8 protein and enhances its degradation.	EPS8 ITSN2	9.73e-06	2	109	2	22449706
Pubmed	Relation between TLR4/NF-κB signaling pathway activation by 27-hydroxycholesterol and 4-hydroxynonenal, and atherosclerotic plaque instability.	NFKB1 TLR4	9.73e-06	2	109	2	25757594
Pubmed	[Investigation of inflammatory responses of alveolar epithelial cells induced by lipopolysaccharide and mechanism].	NFKB1 TLR4	9.73e-06	2	109	2	21729627
Pubmed	Induction of CC and CXC chemokines in human antigen-presenting dendritic cells by the pneumococcal proteins pneumolysin and CbpA, and the role played by toll-like receptor 4, NF-kappaB, and mitogen-activated protein kinases.	NFKB1 TLR4	9.73e-06	2	109	2	18945182
Pubmed	The TLR4/NF-κB signaling pathway mediates the growth of colon cancer.	NFKB1 TLR4	9.73e-06	2	109	2	25555874
Pubmed	Role of the Toll-like receptor 4/NF-kappaB pathway in saturated fatty acid-induced inflammatory changes in the interaction between adipocytes and macrophages.	NFKB1 TLR4	9.73e-06	2	109	2	17082484
Pubmed	HGF and direct mesenchymal stem cells contact synergize to inhibit hepatic stellate cells activation through TLR4/NF-kB pathway.	NFKB1 TLR4	9.73e-06	2	109	2	22927965
Pubmed	[The role of TLR4/NF-κB signaling pathway in sleep deprivation induced Meniere's disease].	NFKB1 TLR4	9.73e-06	2	109	2	37828881
Pubmed	Regulation of lipid-induced macrophage polarization through modulating peroxisome proliferator-activated receptor-gamma activity affects hepatic lipid metabolism via a Toll-like receptor 4/NF-κB signaling pathway.	NFKB1 TLR4	9.73e-06	2	109	2	32128893
Pubmed	Genistein antagonizes inflammatory damage induced by β-amyloid peptide in microglia through TLR4 and NF-κB.	NFKB1 TLR4	9.73e-06	2	109	2	24290604
Pubmed	Clinical Significance of Serum TLR4 and NF-κB Levels in Neonatal Jaundice.	NFKB1 TLR4	9.73e-06	2	109	2	33073966
Pubmed	The elevation of apoB in hypercholesterolemic patients is primarily attributed to the relative increase of apoB/Lp-PLA₂.	PLA2G7 APOB	9.73e-06	2	109	2	24092915
Pubmed	TAK-242 attenuates acute cigarette smoke-induced pulmonary inflammation in mouse via the TLR4/NF-κB signaling pathway.	NFKB1 TLR4	9.73e-06	2	109	2	26944017
Pubmed	Polymorphisms in NFKB1 and TLR4 and interaction with dietary and life style factors in relation to colorectal cancer in a Danish prospective case-cohort study.	NFKB1 TLR4	9.73e-06	2	109	2	25705893
Pubmed	[Expression and significance of toll like receptor 4 mRNA and nuclear factor-kappaB p50 mRNA in human normal nasal mucosa after stimulation by lipopolysaccharide].	NFKB1 TLR4	9.73e-06	2	109	2	17111814
Pubmed	Wogonin improves histological and functional outcomes, and reduces activation of TLR4/NF-κB signaling after experimental traumatic brain injury.	NFKB1 TLR4	9.73e-06	2	109	2	22272328
Pubmed	Toll-Like Receptor (TLR) Signaling Enables Cyclic GMP-AMP Synthase (cGAS) Sensing of HIV-1 Infection in Macrophages.	CGAS TLR4	9.73e-06	2	109	2	34844429
Pubmed	Toll-like receptor 4-mediated nuclear factor kappa B activation is essential for sensing exogenous oxidants to propagate and maintain oxidative/nitrosative cellular stress.	NFKB1 TLR4	9.73e-06	2	109	2	24058497
Pubmed	Type I Interferon Induction by Neisseria gonorrhoeae: Dual Requirement of Cyclic GMP-AMP Synthase and Toll-like Receptor 4.	CGAS TLR4	9.73e-06	2	109	2	27264171
Pubmed	Alpinetin attenuates inflammatory responses by interfering toll-like receptor 4/nuclear factor kappa B signaling pathway in lipopolysaccharide-induced mastitis in mice.	NFKB1 TLR4	9.73e-06	2	109	2	23669335
Pubmed	[The effect of TLR4/NF-kappaB activation and LOX-1 on monocyte adhesion to endothelium].	NFKB1 TLR4	9.73e-06	2	109	2	16266460
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	HCN4 CENPF SRGAP2 SMC2 ZNF462 CCDC88C HOOK3 KIF15 SYNE2 TNKS MTCL1 CNOT1 UNC13A	1.05e-05	963	109	13	28671696
Pubmed	Rapid and efficient cloning of cDNAs encoding Krüppel-like zinc finger proteins by degenerate PCR.	ZNF355P ZNF721 ZNF85 ZNF445	1.73e-05	49	109	4	9630514
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	WDR36 CEP290 SMC2 AMZ2 ZNF462 KMT2C NFKB1 NUP210 CNOT1	1.77e-05	469	109	9	27634302
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	TRIM25 WDR36 GALNT2 CENPF CEP290 MSH2 SMC2 HOOK3 RRP36 SYNE2 NUP210 DDX21 CNOT1	1.99e-05	1024	109	13	24711643
Pubmed	Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray.	WDR36 ZNF235 SLFN13 VAMP7 SHPRH MTCL1 MAP3K13 EXOC7	2.31e-05	371	109	8	15747579
Pubmed	Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.	WDR36 GALNT2 CENPF CNTRL CEP290 RRP36 TLE1 NUP210 TUBGCP3 FASTKD3 DDX21	2.59e-05	754	109	11	33060197
Pubmed	4,7-Dimethoxy-5-methyl-1,3-benzodioxole from Antrodia camphorata inhibits LPS-induced inflammation via suppression of NF-κB and induction HO-1 in RAW264.7 cells.	NFKB1 TLR4	2.91e-05	3	109	2	26745712
Pubmed	Protective mechanism of epigallocatechin-3-gallate against Helicobacter pylori-induced gastric epithelial cytotoxicity via the blockage of TLR-4 signaling.	NFKB1 TLR4	2.91e-05	3	109	2	15610077
Pubmed	Platelet-activating factor: a role in preterm delivery and an essential interaction with Toll-like receptor signaling in mice.	PLA2G7 TLR4	2.91e-05	3	109	2	25253732
Pubmed	Lead exposure induced microgliosis and astrogliosis in hippocampus of young mice potentially by triggering TLR4-MyD88-NFκB signaling cascades.	NFKB1 TLR4	2.91e-05	3	109	2	26386401
Pubmed	Activation of nucleotide oligomerization domain containing protein 1 induces lipolysis through NF-κB and the lipolytic PKA activation in 3T3-L1 adipocytes.	NFKB1 AKAP1	2.91e-05	3	109	2	24219284
Pubmed	Scavenger receptor A (SR-A) is required for LPS-induced TLR4 mediated NF-κB activation in macrophages.	NFKB1 TLR4	2.91e-05	3	109	2	22627090
Pubmed	TLR4/NF-κB axis induces fludarabine resistance by suppressing TXNIP expression in acute myeloid leukemia cells.	NFKB1 TLR4	2.91e-05	3	109	2	30336978
Pubmed	The Effects and Mechanisms of Xanthones in Alzheimer's Disease: A Systematic Review.	NFKB1 TLR4	2.91e-05	3	109	2	37578655
Pubmed	Activation of dendritic cells by human papillomavirus-like particles through TLR4 and NF-kappaB-mediated signalling, moderated by TGF-beta.	NFKB1 TLR4	2.91e-05	3	109	2	15661045
Pubmed	Evaluation of AXIN1 and AXIN2 as targets of tankyrase inhibition in hepatocellular carcinoma cell lines.	AXIN2 TNKS	2.91e-05	3	109	2	33811251
Pubmed	LRRK1 is critical in the regulation of B-cell responses and CARMA1-dependent NF-κB activation.	LRRK1 NFKB1	2.91e-05	3	109	2	27166870
Pubmed	Silencing TLR4/MyD88/NF-κB Signaling Pathway Alleviated Inflammation of Corneal Epithelial Cells Infected by ISE.	NFKB1 TLR4	2.91e-05	3	109	2	33174138
Pubmed	Relationship between Plasma Lipoprotein-Associated Phospholipase A2 Concentrations and Apolipoprotein in Stable Coronary Artery Disease Patients.	PLA2G7 APOB	2.91e-05	3	109	2	33029257
Pubmed	Lipopolysaccharide inhibition of glucose production through the Toll-like receptor-4, myeloid differentiation factor 88, and nuclear factor kappa b pathway.	NFKB1 TLR4	2.91e-05	3	109	2	19492426
Pubmed	Soy phosphatidylcholine inhibited TLR4-mediated MCP-1 expression in vascular cells.	NFKB1 TLR4	2.91e-05	3	109	2	19215923
Pubmed	Peroxiredoxin 1-mediated activation of TLR4/NF-κB pathway contributes to neuroinflammatory injury in intracerebral hemorrhage.	NFKB1 TLR4	2.91e-05	3	109	2	27821296
Pubmed	[HMGB1/TLR4/NF-κB signaling pathway and role of vitamin D in asthmatic mice].	NFKB1 TLR4	2.91e-05	3	109	2	28100331
Pubmed	The role of the Toll receptor pathway in susceptibility to inflammatory bowel diseases.	NFKB1 TLR4	2.91e-05	3	109	2	17538633
Pubmed	Fatty acid-induced induction of Toll-like receptor-4/nuclear factor-kappaB pathway in adipocytes links nutritional signalling with innate immunity.	NFKB1 TLR4	2.91e-05	3	109	2	18624726
Pubmed	Involvement of toll-like receptor 4 in the inflammatory reaction induced by hydroxyapatite particles.	NFKB1 TLR4	2.91e-05	3	109	2	17010424
Pubmed	Activation of TLR4 induces inflammatory muscle injury via mTOR and NF-κB pathways in experimental autoimmune myositis mice.	NFKB1 TLR4	2.91e-05	3	109	2	35276460
Pubmed	NLRC5 deficiency promotes myocardial damage induced by high fat diet in mice through activating TLR4/NF-κB.	NFKB1 TLR4	2.91e-05	3	109	2	28499247
Pubmed	Bcl-6 and NF-kappaB cistromes mediate opposing regulation of the innate immune response.	NFKB1 TLR4	2.91e-05	3	109	2	21106671
Pubmed	Abrogating ClC-3 Inhibits LPS-induced Inflammation via Blocking the TLR4/NF-κB Pathway.	NFKB1 TLR4	2.91e-05	3	109	2	27363391
Pubmed	Dexmedetomidine Resists Intestinal Ischemia-Reperfusion Injury by Inhibiting TLR4/MyD88/NF-κB Signaling.	NFKB1 TLR4	2.91e-05	3	109	2	33383282
Pubmed	Unique Toll-Like Receptor 4 Activation by NAMPT/PBEF Induces NFκB Signaling and Inflammatory Lung Injury.	NFKB1 TLR4	2.91e-05	3	109	2	26272519
Pubmed	Resistin Enhances Inflammatory Cytokine Production in Coronary Artery Tissues by Activating the NF-κB Signaling.	NFKB1 TLR4	2.91e-05	3	109	2	27800490
Pubmed	Human enteric viruses autonomously shape inflammatory bowel disease phenotype through divergent innate immunomodulation.	CGAS TLR4	2.91e-05	3	109	2	35394816
Pubmed	miR‑146b‑5p inhibits tumorigenesis and metastasis of gallbladder cancer by targeting Toll‑like receptor 4 via the nuclear factor‑κB pathway.	NFKB1 TLR4	2.91e-05	3	109	2	33649824
Pubmed	Circ_0026218 ameliorates oxidized low-density lipoprotein-induced vascular endothelial cell dysfunction by regulating miR-188-3p/TLR4/NF-κB pathway.	NFKB1 TLR4	2.91e-05	3	109	2	36585554
Pubmed	MicroRNA-155 deficiency attenuates inflammation and oxidative stress in experimental autoimmune prostatitis in a TLR4-dependent manner.	NFKB1 TLR4	2.91e-05	3	109	2	32436368
Pubmed	Enhancer RNA and NFκB-dependent P300 regulation of ADAMDEC1.	ADAMDEC1 NFKB1	2.91e-05	3	109	2	30352365
Pubmed	Fumigaclavine C inhibits tumor necrosis factor α production via suppression of toll-like receptor 4 and nuclear factor κB activation in macrophages.	NFKB1 TLR4	2.91e-05	3	109	2	21762706
Pubmed	Induction and regulatory function of miR-9 in human monocytes and neutrophils exposed to proinflammatory signals.	NFKB1 TLR4	2.91e-05	3	109	2	19289835
Pubmed	Reactive oxygen and nitrogen species differentially regulate Toll-like receptor 4-mediated activation of NF-kappa B and interleukin-8 expression.	NFKB1 TLR4	2.91e-05	3	109	2	15039334
Pubmed	Role of mitogen-activated protein kinases, nuclear factor-kappaB, and interferon regulatory factor 3 in Toll-like receptor 4-mediated activation of HIV long terminal repeat.	NFKB1 TLR4	2.91e-05	3	109	2	19239434
Pubmed	circ_0001461 promotes oral squamous cell carcinoma progression through miR-145/TLR4/NF-κB axis.	NFKB1 TLR4	2.91e-05	3	109	2	34119822
Pubmed	Eps8 protein facilitates phagocytosis by increasing TLR4-MyD88 protein interaction in lipopolysaccharide-stimulated macrophages.	EPS8 TLR4	2.91e-05	3	109	2	22493489
Pubmed	Complement upregulation in photodynamic therapy-treated tumors: Role of Toll-like receptor pathway and NFkappaB.	NFKB1 TLR4	2.91e-05	3	109	2	19328626
Pubmed	Pyrogenicity of CpG-DNA in mice: role of interleukin-6, cyclooxygenases, and nuclear factor-kappaB.	NFKB1 TLR4	2.91e-05	3	109	2	16293680
Pubmed	Expression of MMR system genes is correlated to NF-kB in patients with oral squamous cell carcinoma.	MSH2 NFKB1	2.91e-05	3	109	2	31662440
Pubmed	BGN/TLR4/NF-B Mediates Epigenetic Silencing of Immunosuppressive Siglec Ligands in Colon Cancer Cells.	NFKB1 TLR4	2.91e-05	3	109	2	32050430
Pubmed	Interaction of PTPRO and TLR4 signaling in hepatocellular carcinoma.	NFKB1 TLR4	2.91e-05	3	109	2	25034527
Pubmed	The role of TLR4/MyD88/NF-κB in the protective effect of ulinastatin on the intestinal mucosal barrier in mice with sepsis.	NFKB1 TLR4	2.91e-05	3	109	2	38102579
Pubmed	Proinflammatory effects of pancreatic elastase are mediated through TLR4 and NF-kappaB.	NFKB1 TLR4	2.91e-05	3	109	2	15351720
Pubmed	Kegan Liyan oral liquid ameliorates lipopolysaccharide-induced acute lung injury through inhibition of TLR4-mediated NF-κB signaling pathway and MMP-9 expression.	NFKB1 TLR4	2.91e-05	3	109	2	27036629
Pubmed	Runt-related Transcription Factor 1 (RUNX1) Binds to p50 in Macrophages and Enhances TLR4-triggered Inflammation and Septic Shock.	NFKB1 TLR4	2.91e-05	3	109	2	27573239
Pubmed	mRNA expression of TLR4, TLR9 and NF-κB in a neonatal murine model of necrotizing enterocolitis.	NFKB1 TLR4	2.91e-05	3	109	2	27357505
Pubmed	Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.	GALNT2 APOB SLC1A4 TNKS	4.15e-05	61	109	4	22916037
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	CUL1 KDM3A TRIM25 UNCX GPS2 MSH2 SMC2 TRIM24 CCDC7 KMT2C TUBGCP3 CNOT1 ZNF292	4.29e-05	1103	109	13	34189442
Pubmed	Genetic variation in 3-hydroxy-3-methylglutaryl CoA reductase modifies the chemopreventive activity of statins for colorectal cancer.	TPMT APOB MSH2 AXIN2	4.43e-05	62	109	4	20403997
Pubmed	Substrate trapping proteomics reveals targets of the βTrCP2/FBXW11 ubiquitin ligase.	CUL1 AXIN2 NFKB1 TNKS CNOT1	5.37e-05	128	109	5	25332235
Pubmed	Crosstalk between the HIF-1 and Toll-like receptor/nuclear factor-κB pathways in the oral squamous cell carcinoma microenvironment.	NFKB1 TLR4	5.82e-05	4	109	2	27191981
Pubmed	Metagenomic analysis of the effects of toll-like receptors on bacterial infection in the peritoneal cavity following cecum ligation and puncture in mice.	NFKB1 TLR4	5.82e-05	4	109	2	31348811
Pubmed	Remote ischemic preconditioning causes transient cell cycle arrest and renal protection by a NF-κB-dependent Sema5B pathway.	NFKB1 TLR4	5.82e-05	4	109	2	35727636
Pubmed	Targeting nuclear factor-κB suppresses the negative effect of toll-like receptor 4 signaling on antimetastasis therapy based on targeting αvβ3.	NFKB1 TLR4	5.82e-05	4	109	2	22494046
Pubmed	Effects of trefoil peptide 3 on expression of TNF-alpha, TLR4, and NF-kappaB in trinitrobenzene sulphonic acid induced colitis mice.	NFKB1 TLR4	5.82e-05	4	109	2	19238529
Pubmed	Toll-like receptor 4 mediates induction of the Bcl10-NFkappaB-interleukin-8 inflammatory pathway by carrageenan in human intestinal epithelial cells.	NFKB1 TLR4	5.82e-05	4	109	2	18252714
Pubmed	Nuclear factor-κB binding motifs specify Toll-like receptor-induced gene repression through an inducible repressosome.	NFKB1 TLR4	5.82e-05	4	109	2	22891325
Pubmed	HIV-1 Tat - TLR4/MD2 interaction drives the expression of IDO-1 in monocytes derived dendritic cells through NF-κB dependent pathway.	NFKB1 TLR4	5.82e-05	4	109	2	32424165
Pubmed	CXC195 suppresses proliferation and inflammatory response in LPS-induced human hepatocellular carcinoma cells via regulating TLR4-MyD88-TAK1-mediated NF-κB and MAPK pathway.	NFKB1 TLR4	5.82e-05	4	109	2	25475726
Pubmed	Ubiquitination of ECSIT is crucial for the activation of p65/p50 NF-κBs in Toll-like receptor 4 signaling.	NFKB1 TLR4	5.82e-05	4	109	2	25355951
Pubmed	Increased MAPK and NF-κB expression of Langerhans cells is dependent on TLR2 and TLR4, and increased IRF-3 expression is partially dependent on TLR4 following UV exposure.	NFKB1 TLR4	5.82e-05	4	109	2	21468605
Pubmed	The evolution of SMC proteins: phylogenetic analysis and structural implications.	SMC2 SMC1B	5.82e-05	4	109	2	14660695
Pubmed	Extracellular histones induce tissue factor expression in vascular endothelial cells via TLR and activation of NF-κB and AP-1.	NFKB1 TLR4	5.82e-05	4	109	2	26476743
Pubmed	Knockdown of FSTL1 inhibits oxLDL-induced inflammation responses through the TLR4/MyD88/NF-κB and MAPK pathway.	NFKB1 TLR4	5.82e-05	4	109	2	27569284
Pubmed	A noisy paracrine signal determines the cellular NF-kappaB response to lipopolysaccharide.	NFKB1 TLR4	5.82e-05	4	109	2	19843957
Interaction	TRIM28 interactions	CUL1 ZNF486 TRIM25 CENPF MSH2 ZNF235 SMC2 TRIM24 SPDL1 ZNF462 UTP15 NFKB1 ZNF721 ZNF84 ZNF85 ZNF649 DDX21 YME1L1 CNOT1 ZNF791 ZNF304 ZNF445	6.95e-06	1474	106	22	int:TRIM28
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZFAT ZNF486 ZNF875 ZNF549 ZNF235 ZNF865 ZNF711 ZNF462 ZNF721 ZNF84 ZNF85 ZNF649 ZNF791 ZNF292 ZNF304 ZNF445	1.35e-08	718	71	16	28
GeneFamily	Structural maintenance of chromosomes proteins\|Cohesin complex	SMC2 SMC1B	3.15e-04	7	71	2	761
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	CUL1 KDM3A EPS8 CENPF PSD3 SRGAP2 MSH2 TRIM24 KIDINS220 TLE1 NFKB1 SYNE2 TUBGCP3 ITSN2 TNKS PKN2 MTCL1 DDX21 ZNF292	2.41e-09	856	109	19	M4500
Coexpression	HAMAI_APOPTOSIS_VIA_TRAIL_UP	ZNF486 RBBP8 CEP290 MSH2 SMC2 TRIM24 SPDL1 KIDINS220 KIF15 SYNE2 ITSN2 GOLIM4 ZNF85 DDX21 ZDHHC11	9.34e-08	656	109	15	M18979
Coexpression	GSE12845_IGD_POS_BLOOD_VS_PRE_GC_TONSIL_BCELL_DN	PLA2G7 RBBP8 LRRK1 SMC2 SLC1A4 SPDL1 KIF15 ADAMDEC1 DDX21	1.62e-07	200	109	9	M3188
Coexpression	HE_LIM_SUN_FETAL_LUNG_C4_CYCLING_NK_CELL	ZWILCH CENPF RBBP8 CGAS MSH2 SMC2 TRIM24 SLC1A4 SPDL1 KIF15 SLFN13 SYNE2 TUBGCP3 ZNF85	1.15e-06	694	109	14	M45767
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN	CUL1 EPS8 CENPF SRGAP2 MSH2 TLE1 TUBGCP3 ITSN2 PKN2 MTCL1 ZNF292	4.00e-06	466	109	11	M13522
Coexpression	PUJANA_BRCA2_PCC_NETWORK	CENPF RBBP8 CNTRL CEP290 MSH2 SMC2 TRIM24 TUBGCP3 ZNF84 ZNF85	1.18e-05	426	109	10	M9516
Coexpression	KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP	CUL1 ZWILCH CENPF SH3GL3 SRGAP2 MSH2 SMC2 SLC1A4 AMZ2 SPDL1 KIF15 TUBGCP3 UBR3 FASTKD3 DDX21 YME1L1 CNOT1	2.35e-05	1290	109	17	M80
Coexpression	YAGI_AML_WITH_T_8_21_TRANSLOCATION	GALNT2 GPS2 PSD3 APOB SLC1A4 NFKB1 NUP210 ZNF85 UNC13A	2.60e-05	372	109	9	M19261
Coexpression	GABRIELY_MIR21_TARGETS	CNTRL MSH2 SYNE2 ITSN2 TLR4 UBR3 YME1L1 ZNF292	2.88e-05	289	109	8	M2196
Coexpression	HE_LIM_SUN_FETAL_LUNG_C5_PRO_B_CELL	CENPF RBBP8 CGAS SMC2 TRIM24 SPDL1 KIF15 SLFN13 SYNE2 TUBGCP3	3.15e-05	478	109	10	M45785
Coexpression	RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP	ZWILCH WDR36 CENPF RBBP8 ZNF549 SRGAP2 SMC2 SLC1A4 KMT2C UTP15 TUBGCP3 CNOT1	4.70e-05	721	109	12	M10237
Coexpression	GSE7509_UNSTIM_VS_FCGRIIB_STIM_MONOCYTE_DN	KDM3A CNTRL SRGAP2 NUP210 TUBGCP3 SNAPC4	6.97e-05	166	109	6	M6826
Coexpression	PUJANA_CHEK2_PCC_NETWORK	CENPF RBBP8 CNTRL MSH2 SMC2 TRIM24 SLC1A4 NUP210 TUBGCP3 GOLIM4 DDX21 CNOT1	7.86e-05	761	109	12	M11961
Coexpression	GSE40493_BCL6_KO_VS_WT_TREG_UP	CUL1 PSD3 UTP15 GOLIM4 PKN2 YME1L1	9.92e-05	177	109	6	M9401
Coexpression	TOYOTA_TARGETS_OF_MIR34B_AND_MIR34C	WDR36 CENPF KIF15 SYNE2 NUP210 TUBGCP3 SHPRH ZNF85 DDX21	1.20e-04	454	109	9	M19927
Coexpression	GSE3400_UNTREATED_VS_IFNB_TREATED_MEF_UP	MSH2 TUBGCP3 SHPRH TNKS SMC1B ZNF304	1.64e-04	194	109	6	M6133
Coexpression	NAKAYA_B_CELL_FLUMIST_AGE_18_50YO_7DY_UP	GALNT2 CEP290 CCDC88C GVINP1 TLE1 TUBGCP3 TNKS AKAP1 YME1L1	1.68e-04	475	109	9	M40979
Coexpression	GSE32423_IL7_VS_IL7_IL4_NAIVE_CD8_TCELL_DN	SLFN13 VAMP7 PKN2 ALDH3B1 FASTKD3 CFAP97	1.93e-04	200	109	6	M5096
Coexpression	GSE23308_CTRL_VS_CORTICOSTERONE_TREATED_MACROPHAGE_MINERALCORTICOID_REC_KO_DN	CUL1 TRIM25 WDR36 CEP290 NFKB1 ITSN2	1.93e-04	200	109	6	M7744
Coexpression	GSE8835_HEALTHY_VS_CLL_CD8_TCELL_UP	SMC2 AXIN2 UTP15 UBR3 TNKS FASTKD3	1.93e-04	200	109	6	M6262
Coexpression	GSE37532_WT_VS_PPARG_KO_LN_TCONV_UP	CYGB KMT2C SLFN13 SHPRH CNOT1 ZNF292	1.93e-04	200	109	6	M8954
Coexpression	GSE29949_CD8_NEG_DC_SPLEEN_VS_DC_BRAIN_DN	PLA2G7 EPS8 CD2 TUBGCP3 PKN2 ZNF84	1.93e-04	200	109	6	M8403
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_MedNas_2500_K1	ZWILCH HCN4 CENPF CNTRL CEP290 SLITRK4 SMC2 TRIM24 SPDL1 ZNF711 ZNF462 CCDC88C KIF15 ADAMDEC1 SYNE2 MYLK4 NUP210 ZNF292	4.18e-06	1060	105	18	facebase_RNAseq_e10.5_Emin_MedNas_2500_K1
CoexpressionAtlas	DevelopingGonad_e12.5_ovary_emap-28876_k-means-cluster#5_top-relative-expression-ranked_1000	CEP290 ZNF711 SYNE2 VAMP7 SHPRH YME1L1 CFAP97 SMC1B	2.08e-05	233	105	8	gudmap_developingGonad_e12.5_ovary_k5_1000
CoexpressionAtlas	DevelopingGonad_e16.5_ovary_emap-9563_top-relative-expression-ranked_1000	CEP290 SLITRK4 SMC2 TRIM24 ZNF711 KMT2C SEMA6D SYNE2 ERMAP SHPRH YME1L1 CFAP97 SMC1B ZNF445	3.70e-05	795	105	14	gudmap_developingGonad_e16.5_ovary_1000
CoexpressionAtlas	facebase_RNAseq_e10.5_MaxArch_2500_K3	UNCX CENPF RBBP8 CNTRL CEP290 SLITRK4 SMC2 TRIM24 SPDL1 ZNF711 ZNF462 KIF15 GVINP1 SYNE2 MYLK4 UBR3 CFAP97 ZNF292	3.95e-05	1252	105	18	facebase_RNAseq_e10.5_MaxArch_2500_K3
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_LatNas_2500_K3	TPMT ZWILCH CENPF RBBP8 CNTRL CEP290 SMC2 TRIM24 SPDL1 ZNF711 ZNF462 CCDC88C HOOK3 KIF15 TLE1 SYNE2 CFAP97 ZNF292	4.16e-05	1257	105	18	facebase_RNAseq_e10.5_Emin_LatNas_2500_K3
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_MedNas_2500	ZWILCH UNCX HCN4 CENPF CNTRL CEP290 SLITRK4 SMC2 TRIM24 SPDL1 ZNF711 ZNF462 CCDC88C KIF15 ADAMDEC1 SYNE2 MYLK4 NUP210 ZNF292	5.85e-05	1414	105	19	facebase_RNAseq_e10.5_Emin_MedNas_2500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#5	CENPF CEP290 SLITRK4 SMC2 TRIM24 ZFAND4 ZNF711 SYNE2 UBR3 YME1L1 ZNF292 ZNF445	6.51e-05	629	105	12	Facebase_RNAseq_e10.5_Maxillary Arch_2500_K5
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_LatNas_2500	TPMT ZWILCH UNCX CENPF RBBP8 CNTRL CEP290 SMC2 TRIM24 SPDL1 ZNF711 ZNF462 CCDC88C HOOK3 KIF15 TLE1 SYNE2 CFAP97 ZNF292	8.89e-05	1459	105	19	facebase_RNAseq_e10.5_Emin_LatNas_2500
CoexpressionAtlas	DevelopingGonad_e16.5_ovary_emap-9563_k-means-cluster#5_top-relative-expression-ranked_1000	CEP290 ZNF711 KMT2C SEMA6D ERMAP SHPRH SMC1B	1.09e-04	219	105	7	gudmap_developingGonad_e16.5_ovary_1000_k5
CoexpressionAtlas	DevelopingGonad_e11.5_ovary + mesonephros_emap-3226_k-means-cluster#4_top-relative-expression-ranked_500	SMC2 TRIM24 ZNF711 SYNE2 YME1L1 ZNF445	2.15e-04	172	105	6	gudmap_developingGonad_e11.5_ovary + mesonephros_k4_500
ToppCell	droplet-Limb_Muscle-MUSCLE-30m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CNTRL CGAS CCDC88C GVINP1 SYNE2 ITSN2 TNKS PKN2	1.29e-08	178	108	8	01dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CENPF CCDC168 SMC2 SPDL1 ZNF462 KIF15 UNC13A	1.81e-07	168	108	7	a7eb28e15b591997f1aee09501cb20ae18beca08
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-Prolif_T-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	RBBP8 SMC2 CCDC88C CD2 KIF15 GVINP1 SYNE2	4.32e-07	191	108	7	912e2d10d3423aa7f708fcf2b11da1845f12d7d3
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-Prolif_T\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	RBBP8 SMC2 CCDC88C CD2 KIF15 GVINP1 SYNE2	4.32e-07	191	108	7	77a2746b6d9c53b08d4405411c16fcc5a6c734ce
ToppCell	control-Lymphocytic-Prol._cells\|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	ZWILCH CENPF RBBP8 SMC2 SLC1A4 SPDL1 KIF15	5.14e-07	196	108	7	886f7c865b086d6ebb4a1746865c30af6bbed345
ToppCell	(11)_FOXN4+-(2)_GFP_FOXI1\|(11)_FOXN4+ / shred by cell type by condition	CUL1 EPS8 CENPF CNTRL CEP290 TRIM24 SYNE2	5.51e-07	198	108	7	76d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZWILCH CENPF SMC2 CD2 KIF15 CA5B	4.38e-06	175	108	6	9de288c338cee67be0e9b836c87799bbc1db1c38
ToppCell	facs-Marrow-Granulocytes-18m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CENPF SMC2 KIF15 SYNE2 GOLIM4 ALDH3B1	4.83e-06	178	108	6	15a99080e9f669572ab6d82934f324e6714846c1
ToppCell	facs-Marrow-Granulocytes-18m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CENPF SMC2 KIF15 SYNE2 GOLIM4 ALDH3B1	4.83e-06	178	108	6	200308e109abb7e6f8816a6f8cce6d56862d4098
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-T_cell-T_cells_proliferating-T_cells_proliferating_L.1.1.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CENPF SMC2 SPDL1 CD2 KIF15 NUP210	5.84e-06	184	108	6	8260e688ec42a1374727bc85dceb7edd19a8b662
ToppCell	Control-Lymphoid-ILC_A\|Lymphoid / Disease state, Lineage and Cell class	CYGB SLFN13 TLE1 NFKB1 GOLIM4 MTCL1	6.02e-06	185	108	6	520795866d44def5be3910ce8e728045c716a24d
ToppCell	droplet-Marrow-nan-3m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GALNT2 RBBP8 CNTRL CGAS SYNE2 GOLIM4	6.40e-06	187	108	6	14c239af77116d28d511dea754b6150d20488080
ToppCell	droplet-Spleen-nan-18m-Lymphocytic-immature_NKT_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZWILCH CENPF RBBP8 CGAS SMC2 KIF15	7.01e-06	190	108	6	b99271d139c8d01e20feb95d99f79c9b2756b4cb
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZWILCH CENPF RBBP8 SMC2 SPDL1 KIF15	7.23e-06	191	108	6	50854384fdaa0efa2e3227659d544ed09ac102f2
ToppCell	367C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	ZWILCH CENPF SMC2 SPDL1 KIF15 SLFN13	8.38e-06	196	108	6	9591a6a3477ed6a1e2e016f7542e38603d8b16cb
ToppCell	343B-Myeloid-Dendritic-cDC_proliferating_1\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	ZWILCH CENPF SMC2 SPDL1 KIF15 SLFN13	8.87e-06	198	108	6	281fc2536cdc4c717b30de156e563c0e4baba99d
ToppCell	MNPs-Dividing_Macrophages\|MNPs / lung cells shred on cell class, cell subclass, sample id	ZWILCH CENPF SMC2 SPDL1 KIF15 SLFN13	9.13e-06	199	108	6	5952980d0ece5d73f3e9f340c56a38b34d2f2309
ToppCell	(02)_MMP9/10+-(2)_GFP_FOXI1\|(02)_MMP9/10+ / shred by cell type by condition	EPS8 CEP290 SYNE2 ITSN2 GOLIM4 CFAP97	9.13e-06	199	108	6	18a7f9ced4364f45b184bd529f32ef02c27779d3
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW13-Stem_cells\|GW13 / Sample Type, Dataset, Time_group, and Cell type.	CENPF SMC2 KIF15 TUBGCP3 GOLIM4 ZNF85	9.13e-06	199	108	6	fd1d1b95e01719e3d0a17d9d1f29717a47209d32
ToppCell	367C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	ZWILCH CENPF SMC2 SPDL1 KIF15 SLFN13	9.13e-06	199	108	6	88d130e2451e61afb710edf552e6b346b9fcfb2b
ToppCell	(03)_KRT6B+-(2)_GFP_FOXI1\|(03)_KRT6B+ / shred by cell type by condition	EPS8 CEP290 SYNE2 ITSN2 CFAP97 ZNF292	9.13e-06	199	108	6	c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCell	severe-Lymphocytic-Prol._cells\|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	ZWILCH CENPF MSH2 SMC2 SPDL1 KIF15	9.13e-06	199	108	6	b24315952b6ac6c8d2d3a7bd949a5b5392624d4e
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-FOXM1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ZWILCH CENPF CNTRL SMC2 KIF15 SYNE2	9.13e-06	199	108	6	98575fcce726589e93fbb4df1aab03e57cb56076
ToppCell	LPS_IL1RA-Endothelial-Endothelial-FOXM1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	CENPF CNTRL SMC2 SPDL1 KIF15 SYNE2	9.13e-06	199	108	6	be2276c9a1994579ba1d2998b49bf549c1324d44
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW13-Stem_cells-Stem_cells\|GW13 / Sample Type, Dataset, Time_group, and Cell type.	CENPF SMC2 KIF15 TUBGCP3 GOLIM4 ZNF85	9.13e-06	199	108	6	91882af9dc7265c9b419f4415cbcf656087a2ab3
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW13-Stem_cells\|GW13 / Sample Type, Dataset, Time_group, and Cell type.	CENPF SMC2 KIF15 GOLIM4 ZNF721 ZNF85	9.40e-06	200	108	6	d933978b55fefe52cad599b36f6b47a0c7f71f96
ToppCell	Biopsy_Control_(H.)-Immune-Proliferating_Macrophages\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	ZWILCH CENPF SMC2 SPDL1 KIF15 SMC1B	9.40e-06	200	108	6	ce9fad55f779afd3d6c5a9c5a15e2d9f548b7c7e
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	KMT2C SYNE2 ITSN2 PKN2 DDX21 ZNF292	9.40e-06	200	108	6	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW13-Stem_cells-Neuroepithelial_cell\|GW13 / Sample Type, Dataset, Time_group, and Cell type.	CENPF SMC2 KIF15 GOLIM4 ZNF721 ZNF85	9.40e-06	200	108	6	3d932765c31aef1f80a118d51e8e66c50a758dbb
ToppCell	COVID_vent-Lymphocytic-Proliferative_Lymphocyte-\|COVID_vent / Disease condition, Lineage, Cell class and subclass	CENPF RBBP8 MSH2 SMC2 SPDL1 KIF15	9.40e-06	200	108	6	7e4c0db43a03ca11380a54f44a3cf1991e055b80
ToppCell	COVID_vent-Lymphocytic-Proliferative_Lymphocyte\|COVID_vent / Disease condition, Lineage, Cell class and subclass	CENPF RBBP8 MSH2 SMC2 SPDL1 KIF15	9.40e-06	200	108	6	9775ca7dedb76fcbb74f80f86b33c94e394c320a
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ZNF235 ZNF711 CCDC88C ZNF84 MTCL1	3.15e-05	149	108	5	4b44108c40376a6b73258df40d2424e68f991383
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CENPF SPDL1 KIF15 SLFN13 MTCL1	5.13e-05	165	108	5	88681101d7cf60b99b8ace5d8c0944323b937306
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZWILCH CENPF SMC2 SPDL1 KIF15	5.28e-05	166	108	5	a41a20cef053c67da2d435e3e132ce28f1661c03
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c03-MKI67\|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CENPF RBBP8 SPDL1 KIF15 SMC1B	5.43e-05	167	108	5	9280558baddea51aae47f3383d895a9b0c6749a4
ToppCell	facs-Marrow-KLS-3m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFAT AXIN2 CUEDC1 CKM ZNF791	5.43e-05	167	108	5	2812353ff66e76f10bd327ceb0e6b009502a5258
ToppCell	facs-Marrow-KLS-3m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFAT AXIN2 CUEDC1 CKM ZNF791	5.43e-05	167	108	5	d15168f46c1599d9fc68a05a7b822c4b439f2987
ToppCell	PND14-Immune-Immune_Myeloid-DC-cDC2-cDC2_G2M\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CENPF CGAS SMC2 SPDL1 KIF15	5.59e-05	168	108	5	b7cd33f5da4f37b9384fc3bd3ca01fbc790accfc
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CENPF TMPRSS5 SMC2 SPDL1 KIF15	5.75e-05	169	108	5	563c267edaade0e5df192ad953801ef9768d4270
ToppCell	PND03-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CENPF CGAS SMC2 SPDL1 KIF15	5.75e-05	169	108	5	4db49b7eaea34e6558ee73b01e76315e99cc880b
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CENPF SMC2 C8orf34 KIF15 CA5B	6.08e-05	171	108	5	846a9acfff0bf0a9baf65dc07b7d7a9217ed6598
ToppCell	droplet-Lung-nan-18m-Lymphocytic-Proliferating_NK\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CENPF SH3GL3 SMC2 KIF15 NUP210	6.25e-05	172	108	5	e495efd25aec60b97ac2b5aa861651bd73174a17
ToppCell	facs-Marrow-Granulocytes-24m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPMT BEST1 AXIN2 CUEDC1 HOOK3	6.42e-05	173	108	5	a5b6c3d58f7a8e533330798b81496009a31548af
ToppCell	facs-Marrow-Granulocytes-24m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPMT BEST1 AXIN2 CUEDC1 HOOK3	6.42e-05	173	108	5	cc094992b8027f4cef38f0fb0b76f0d07210d1e2
ToppCell	PND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZWILCH CENPF SRGAP2 SMC2 KIF15	6.60e-05	174	108	5	72df66319f6efbd88ecf439013d97409fbf3cb52
ToppCell	PND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZWILCH CENPF SRGAP2 SMC2 KIF15	6.60e-05	174	108	5	c6087fd0e036ec7f40f0f8f17d1f6ce13ddb5235
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZWILCH CENPF SMC2 KIF15 NUP210	6.60e-05	174	108	5	7b2f35add804981c7d588a996bdbca6ec11a1ca5
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZWILCH CENPF CYGB PTHLH CA5B	6.60e-05	174	108	5	1779e67382cb2644534ffb5b9b8f28d32935f4ea
ToppCell	PBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_CD56bright-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CYGB CD2 SLFN13 TLE1 GOLIM4	6.78e-05	175	108	5	0ed053aa8353c72ff37fee830672704a3ddc7d85
ToppCell	systemic_lupus_erythematosus-managed-Lymphocytic_B-plasmablast-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	CENPF RBBP8 PLEKHG7 SLC1A4 KIF15	6.78e-05	175	108	5	89bf89466191da14896ed8928027f5b911436c22
ToppCell	PBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_CD56bright\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	CYGB CD2 SLFN13 TLE1 GOLIM4	6.78e-05	175	108	5	0124a3c4696b39cee8b566e94603d1d3d128bfa5
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZWILCH CENPF CCDC168 SMC2 KIF15	6.78e-05	175	108	5	d43ae33a6256606ce848247cad32d74f21b38988
ToppCell	PBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_CD56bright\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CYGB CD2 SLFN13 TLE1 GOLIM4	6.78e-05	175	108	5	e219b61d6bc078d44ea7d06191d3462654d857a1
ToppCell	367C-Lymphocytic-NK_cells-Proliferating_NK_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	CENPF RBBP8 SMC2 SPDL1 KIF15	6.78e-05	175	108	5	0b1aaa028ba844d4bcb4509fdab8bee648373935
ToppCell	PBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_CD56bright-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CYGB CD2 SLFN13 TLE1 GOLIM4	6.78e-05	175	108	5	bd16c80418bf71127e6f1e50edf83967c9218b42
ToppCell	droplet-Lung-18m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-proliferating_NK\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CENPF SH3GL3 SMC2 CKM KIF15	6.96e-05	176	108	5	b17317ac41d3215db55a38cbd3366c0947f7a2a3
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CENPF SMC2 SPDL1 KIF15 MYLK4	6.96e-05	176	108	5	45c6983ab671b0f306e7390320bd84f848e474cc
ToppCell	PND01-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZWILCH CENPF SMC2 SPDL1 KIF15	6.96e-05	176	108	5	8385435074cc5235b7af7424974f609388fc2cff
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_12\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RBBP8 SMC2 SLC1A4 MAP3K13 SMC1B	7.15e-05	177	108	5	cbedac0bddb8fc330a464815c905928c553b0fc0
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_12\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	RBBP8 SMC2 SLC1A4 MAP3K13 SMC1B	7.35e-05	178	108	5	04bfecf5ea5d85c843e48d08718b5d69e7bf834e
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZWILCH CENPF SMC2 SPDL1 KIF15	7.54e-05	179	108	5	54191c00b29f53b520cd3243b5791daa4a2c72d7
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZWILCH CENPF SMC2 SPDL1 KIF15	7.74e-05	180	108	5	5e1680088065be14447d5d5465f91f7edd071a1e
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c11-MKI67-FOS\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CENPF SMC2 SPDL1 CD2 KIF15	7.95e-05	181	108	5	6873c1138b28c130637d06b64981ad11c262e85f
ToppCell	facs-Marrow-B-cells-18m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CENPF SMC2 KIF15 SYNE2 GOLIM4	8.16e-05	182	108	5	9025178ede571e3808d4657ad4892152f336c9b4
ToppCell	facs-Marrow-B-cells-18m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CENPF SMC2 KIF15 SYNE2 GOLIM4	8.16e-05	182	108	5	c075756cd4bb484ede1be2bcdb9eac60eab0573a
ToppCell	Calu_3-infected\|Calu_3 / Cell line, Condition and Strain	TRIM25 KMT2C SYNE2 PKN2 ZNF292	8.37e-05	183	108	5	8f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCell	Control-T/NK-proliferating_T/NK\|Control / Disease group,lineage and cell class （2021.01.30）	CENPF ZNF462 KIF15 MTCL1 SMC1B	8.37e-05	183	108	5	e740f05536d1e4b2512811771928eb65f6696409
ToppCell	droplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CENPF SMC2 ZFAND4 KIF15 FASTKD3	8.37e-05	183	108	5	6c1d7ce60e67bf1df364a4e177c351e7313eb41f
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZWILCH CENPF SMC2 SPDL1 KIF15	8.59e-05	184	108	5	d1e0e3b0eed2db8a5b7e3d6f81294667e4ba64e5
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CCDC88C CD2 GVINP1 SLFN13 SYNE2	9.04e-05	186	108	5	71e87c4c755ab607689cb050f5a363cb520a0f53
ToppCell	COVID_vent-Myeloid-Dendritic\|COVID_vent / Disease condition, Lineage, Cell class and subclass	CUL1 EPS8 LRRK1 ZNF385A NFKB1	9.04e-05	186	108	5	63a5cdd3f60681762a218be32db84be8f29b88fd
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-Lgr5-_amplifying_undifferentiated_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CENPF CNTRL KIF15 SYNE2 DDX21	9.04e-05	186	108	5	15ab6666748a641226e42e6ca6eeaf186a501c95
ToppCell	COVID_vent-Myeloid-Dendritic-cDC\|COVID_vent / Disease condition, Lineage, Cell class and subclass	CUL1 EPS8 LRRK1 ZNF385A NFKB1	9.04e-05	186	108	5	39457a7b43537f2c3e221f9375c95d4515424d7d
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-epithelial_cell_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CENPF CNTRL KIF15 SYNE2 DDX21	9.04e-05	186	108	5	4ed1b97e2552f3c4134f25665d7513498ffac16c
ToppCell	tumor_Lymph_Node_/_Brain-Fibroblasts-Undetermined\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	ZNF486 TRIM25 CYGB AXIN2 CA5B	9.50e-05	188	108	5	8231e635706a296db6b6da1029a33bbc1b52478e
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZWILCH CENPF SMC2 SPDL1 KIF15	9.50e-05	188	108	5	95d0a796d62ce6d121e2028c378faffc14b35275
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like_Prolif-E\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HCN4 CENPF GPS2 KIF15 GOLIM4	9.50e-05	188	108	5	0476d7ee3e0ce78c3c5b111e9ade01098f9ea7ec
ToppCell	367C-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	RBBP8 SMC2 CKM KIF15 SMC1B	9.50e-05	188	108	5	f5102e8d95506c25c675094b86162a6a50087b64
ToppCell	COVID-19-lung-Plasma_cells_PRDM1/BLIMP_hi\|COVID-19 / Disease (COVID-19 only), tissue and cell type	LRRK1 SLC1A4 CCDC88C KIF15 NUP210	9.50e-05	188	108	5	567b08514d9d84cbb40f9b7a679eec304f023428
ToppCell	facs-Skin-Anagen-3m-Epithelial-actively_dividing_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZWILCH CENPF SMC2 SPDL1 KIF15	9.74e-05	189	108	5	bfa3ed1360991a3e32fad133017c413f8adc1eba
ToppCell	facs-Skin-Anagen-3m-Epithelial-keratinocyte_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZWILCH CENPF SMC2 SPDL1 KIF15	9.74e-05	189	108	5	96f10c63656e446b4bb712f012e91ae986f8c2d0
ToppCell	Dividing_Macrophages-SSc-ILD_02\|World / lung cells shred on cell class, cell subclass, sample id	CENPF SMC2 KIF15 SLFN13 SMC1B	9.74e-05	189	108	5	d4e88a3e50499d683e3db38aee04490146fe30bb
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EPS8 C8orf34 ZNF462 SEMA6D GOLIM4	9.99e-05	190	108	5	2f54da2bee411f8868348a4c37034184b8f58a89
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CENPF CNTRL SMC2 SPDL1 KIF15	9.99e-05	190	108	5	cd37ccd30c27cf65eda0a9165f35b7672f5acaf6
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_NK-Cycling_NK\|lymph-node_spleen / Manually curated celltypes from each tissue	CENPF SMC2 KIF15 SLFN13 SMC1B	9.99e-05	190	108	5	451eaceb0cb0ec6cfcae00253c0e5c92a168c2f3
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CNTRL APOB SYNE2 GOLIM4 PKN2	1.02e-04	191	108	5	60c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCell	Endothelial-D_(cycle)\|World / shred on cell class and cell subclass (v4)	ZWILCH CENPF SMC2 SPDL1 KIF15	1.02e-04	191	108	5	49a4d8f181558e3be9527a8ff9a178f3bb01323c
ToppCell	COVID-19-kidney-Proliferating_T_cell\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CENPF SMC2 CD2 KIF15 NUP210	1.02e-04	191	108	5	bae388e0e9447d576e68465d73d8313ef6925ffa
ToppCell	Endothelial-Endothelial-D_(cycle)\|Endothelial / shred on cell class and cell subclass (v4)	ZWILCH CENPF SMC2 SPDL1 KIF15	1.02e-04	191	108	5	a3c5a913a99f17633c140ec9ece81b73e59e0715
ToppCell	P03-Mesenchymal-developing_mesenchymal_cell-mesenchymal_proliferating_cell\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ZWILCH CENPF SMC2 SPDL1 KIF15	1.02e-04	191	108	5	b978afe76754cc56e1672abca27be289bb56375b
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CNTRL APOB SYNE2 GOLIM4 PKN2	1.02e-04	191	108	5	09db184cb90fe282a14474d7217068c58092c6f8
ToppCell	COVID-19-T_cells\|COVID-19 / group, cell type (main and fine annotations)	CENPF CCDC88C CD2 SYNE2 NUP210	1.02e-04	191	108	5	7f64add931b64b8d35836fa6bee9ebab593844d3
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CNTRL APOB SYNE2 GOLIM4 PKN2	1.02e-04	191	108	5	973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCell	droplet-Skin-nan-21m-Epithelial-stem_cell_of_epidermis\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZWILCH CENPF SMC2 SPDL1 KIF15	1.05e-04	192	108	5	96f23d6e8604d1cb24910d3118d8171b57c93e14
ToppCell	Proliferating\|World / shred by cell class for mouse tongue	ZWILCH CENPF SMC2 SPDL1 KIF15	1.05e-04	192	108	5	f081f3f957cc782294e118fcc1055f6a4264ee98
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	ZNF711 TLE1 NFKB1 ITSN2 DDX21	1.07e-04	193	108	5	08696a99309f5b088692ddac8cca35413b5e810d
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZWILCH CENPF SMC2 SPDL1 KIF15	1.07e-04	193	108	5	a332dfdcc48c405020014e644aa4d14fda98cc86
ToppCell	droplet-Tongue-nan-24m-Epithelial-proliferating\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZWILCH CENPF SMC2 SPDL1 KIF15	1.07e-04	193	108	5	f20b90e3f3f5c9a1ae51c5ebe6d3adb954a142f2
ToppCell	droplet-Tongue-nan-3m-Epithelial-proliferating\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZWILCH CENPF SMC2 SPDL1 KIF15	1.10e-04	194	108	5	2cac1b9c4da01faaec9a67ec06f47a7060760225
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-innate_lymphocytic\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	CENPF CCDC88C KIF15 SLFN13 SYNE2	1.10e-04	194	108	5	8bfd7c5be518b81b17913139bcb3ebea01f48dd5
Disease	polyunsaturated fatty acids to monounsaturated fatty acids ratio	BEST1 GALNT2 PSD3 APOB	3.08e-05	51	103	4	EFO_0022302
Disease	triglycerides in LDL measurement	GALNT2 PSD3 APOB SYNE2	4.47e-05	56	103	4	EFO_0022320
Disease	atrial fibrillation	KDM3A ZFAT HCN4 CCDC7 ZNF462 SYNE2 PKN2 ZNF292	4.87e-05	371	103	8	EFO_0000275
Disease	monounsaturated fatty acids; 16:1, 18:1 measurement	BEST1 GALNT2 PSD3 APOB	1.64e-04	78	103	4	EFO_0022187
Disease	triglycerides:total lipids ratio, low density lipoprotein cholesterol measurement	GALNT2 PSD3 APOB SYNE2 TNKS	1.86e-04	150	103	5	EFO_0004611, EFO_0020947
Disease	triacylglycerol 52:4 measurement	GALNT2 APOB CNOT1	2.71e-04	36	103	3	EFO_0010416
Disease	triglyceride measurement, low density lipoprotein cholesterol measurement	GALNT2 PSD3 APOB SYNE2 TNKS	2.98e-04	166	103	5	EFO_0004530, EFO_0004611
Disease	degree of unsaturation measurement	BEST1 GALNT2 APOB	3.45e-04	39	103	3	EFO_0022261
Disease	chylomicron measurement, very low density lipoprotein cholesterol measurement, lipid measurement	GALNT2 PSD3 APOB TNKS	3.49e-04	95	103	4	EFO_0004529, EFO_0008317, EFO_0008596
Disease	phosphatidylinositol measurement	BEST1 GALNT2 APOB UNC13A	3.49e-04	95	103	4	EFO_0010230
Disease	chylomicron measurement, triglyceride measurement, very low density lipoprotein cholesterol measurement	GALNT2 PSD3 APOB TNKS	3.64e-04	96	103	4	EFO_0004530, EFO_0008317, EFO_0008596
Disease	skin aging measurement	PSD3 KIDINS220 SBF2 SYNE2 AKAP1	4.43e-04	181	103	5	EFO_0008006
Disease	triglycerides in large LDL measurement	GALNT2 APOB SYNE2	4.61e-04	43	103	3	EFO_0022319
Disease	sleep duration, triglyceride measurement	GALNT2 PSD3 APOB TNKS	4.93e-04	104	103	4	EFO_0004530, EFO_0005271
Disease	chylomicron measurement, very low density lipoprotein cholesterol measurement	GALNT2 PSD3 APOB TNKS	5.29e-04	106	103	4	EFO_0008317, EFO_0008596
Disease	chylomicron measurement, very low density lipoprotein cholesterol measurement, phospholipid measurement	GALNT2 PSD3 APOB TNKS	5.88e-04	109	103	4	EFO_0004639, EFO_0008317, EFO_0008596
Disease	cholesteryl ester measurement, chylomicron measurement, very low density lipoprotein cholesterol measurement	GALNT2 PSD3 APOB TNKS	6.09e-04	110	103	4	EFO_0008317, EFO_0008596, EFO_0010351
Disease	free cholesterol measurement, chylomicron measurement, very low density lipoprotein cholesterol measurement	GALNT2 PSD3 APOB TNKS	6.09e-04	110	103	4	EFO_0008317, EFO_0008591, EFO_0008596
Disease	chylomicron measurement, total cholesterol measurement, very low density lipoprotein cholesterol measurement	GALNT2 PSD3 APOB TNKS	6.09e-04	110	103	4	EFO_0004574, EFO_0008317, EFO_0008596
Disease	triglyceride measurement, intermediate density lipoprotein measurement	GALNT2 PSD3 APOB SYNE2	6.30e-04	111	103	4	EFO_0004530, EFO_0008595
Disease	lung adenocarcinoma (is_implicated_in)	MSH2 AXIN2 KMT2C	6.77e-04	49	103	3	DOID:3910 (is_implicated_in)
Disease	polyunsaturated fatty acids to total fatty acids percentage	GALNT2 PSD3 APOB	7.19e-04	50	103	3	EFO_0022303
Disease	Emery-Dreifuss muscular dystrophy (implicated_via_orthology)	HOOK3 SYNE2	7.78e-04	12	103	2	DOID:11726 (implicated_via_orthology)
Disease	triglycerides:total lipids ratio, high density lipoprotein cholesterol measurement	GALNT2 PSD3 APOB SYNE2 TNKS	7.95e-04	206	103	5	EFO_0004612, EFO_0020947
Disease	free cholesterol to total lipids in small LDL percentage	GALNT2 PSD3 APOB	8.52e-04	53	103	3	EFO_0022286
Disease	gallbladder cancer (is_implicated_in)	APOB AXIN2	9.18e-04	13	103	2	DOID:3121 (is_implicated_in)
Disease	triglycerides in very large HDL measurement	UNCX PSD3 APOB	9.50e-04	55	103	3	EFO_0022324
Disease	triglycerides in chylomicrons and extremely large VLDL measurement	GALNT2 PSD3 APOB	1.00e-03	56	103	3	EFO_0022316
Disease	triglycerides:total lipids ratio, intermediate density lipoprotein measurement	GALNT2 PSD3 APOB SYNE2	1.04e-03	127	103	4	EFO_0008595, EFO_0020947
Disease	triglycerides in IDL measurement	GALNT2 PSD3 APOB	1.11e-03	58	103	3	EFO_0022149
Disease	triglyceride measurement, very low density lipoprotein cholesterol measurement	GALNT2 PSD3 APOB SYNE2 TNKS	1.15e-03	224	103	5	EFO_0004530, EFO_0008317
Disease	triglycerides to total lipids in small LDL percentage	GALNT2 PSD3 APOB	1.17e-03	59	103	3	EFO_0022337
Disease	concentration of chylomicrons and extremely large VLDL particles measurement	GALNT2 PSD3 APOB	1.17e-03	59	103	3	EFO_0022260
Disease	cholesterol in chylomicrons and extremely large VLDL measurement	GALNT2 PSD3 APOB	1.22e-03	60	103	3	EFO_0021898
Disease	cholesterol to total lipids in IDL percentage	GALNT2 APOB CKM	1.22e-03	60	103	3	EFO_0022233
Disease	triacylglycerol 52:3 measurement	GALNT2 APOB	1.23e-03	15	103	2	EFO_0010415
Disease	very low density lipoprotein particle size measurement	GALNT2 PSD3 APOB TNKS	1.24e-03	133	103	4	EFO_0008594
Disease	triglycerides in medium LDL measurement	GALNT2 PSD3 APOB	1.35e-03	62	103	3	EFO_0022322
Disease	total lipids in chylomicrons and extremely large VLDL measurement	GALNT2 PSD3 APOB	1.35e-03	62	103	3	EFO_0022306
Disease	free cholesterol in chylomicrons and extremely large VLDL measurement	GALNT2 PSD3 APOB	1.35e-03	62	103	3	EFO_0022263
Disease	shigellosis	MYLK4 YME1L1	1.40e-03	16	103	2	EFO_0005585
Disease	free cholesterol to total lipids in medium LDL percentage	GALNT2 PSD3 APOB	1.41e-03	63	103	3	EFO_0022283
Disease	phospholipids in chylomicrons and extremely large VLDL measurement	GALNT2 PSD3 APOB	1.41e-03	63	103	3	EFO_0022292
Disease	triglycerides in small LDL measurement	GALNT2 PSD3 APOB	1.54e-03	65	103	3	EFO_0022323
Disease	renal fibrosis (implicated_via_orthology)	CYGB TLR4	1.59e-03	17	103	2	DOID:0050855 (implicated_via_orthology)
Disease	triglycerides in very small VLDL measurement	GALNT2 PSD3 APOB	1.76e-03	68	103	3	EFO_0022144
Disease	triglycerides to total lipids in very small VLDL percentage	GALNT2 PSD3 APOB	1.83e-03	69	103	3	EFO_0022341
Disease	cerebral infarction (is_marker_for)	PLA2G7 APOB	1.99e-03	19	103	2	DOID:3526 (is_marker_for)
Disease	cholesteryl ester measurement	BEST1 GALNT2 PSD3 APOB SBF2	2.11e-03	257	103	5	EFO_0010351
Disease	free cholesterol to total lipids in large LDL percentage	GALNT2 PSD3 APOB	2.24e-03	74	103	3	EFO_0022280
Disease	free cholesterol to total lipids in small VLDL percentage	GALNT2 PSD3 APOB	2.32e-03	75	103	3	EFO_0022287
Disease	docosahexaenoic acid to total fatty acids percentage	GALNT2 APOB	2.43e-03	21	103	2	EFO_0022262
Disease	white matter microstructure measurement	APOB SRGAP2 PTHLH TNKS PKN2 MAP3K13	2.50e-03	390	103	6	EFO_0005674
Disease	Seckel syndrome	CENPF RBBP8	2.66e-03	22	103	2	C0265202
Disease	Primary microcephaly	RBBP8 TUBGCP3	2.66e-03	22	103	2	C0431350
Disease	primary open angle glaucoma (is_implicated_in)	WDR36 TLR4	2.91e-03	23	103	2	DOID:1070 (is_implicated_in)
Disease	Coronary heart disease	PLA2G7 APOB	3.17e-03	24	103	2	C0010068
Disease	Behcet Syndrome	APOB TLR4	3.17e-03	24	103	2	C0004943
Disease	nephrotic syndrome (biomarker_via_orthology)	PLA2G7 APOB	3.17e-03	24	103	2	DOID:1184 (biomarker_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
NAAKELGQLSKLKDH	UNC13A	1431	Q9UPW8
LEAHNKGTKHKTILE	ZNF385A	216	Q96PM9
QHHVDKALNLIGKKF	AKAP1	661	Q92667
LGKHHKELQKLVDTL	CA5B	186	Q9Y2D0
RQLGHKKEELHLLQG	CNTRL	1601	Q7Z7A1
KAFLQLDKKGPQKHH	CFAP97	351	Q9P2B7
LHTHGDKQDKVKQKA	RBBP8	761	Q99708
LSPELKEKHNAKLIH	CCDC7	31	Q96M83
KQLLHDALAQDLHKS	ALDH3B1	41	P43353
DGKHLKLSQRVITHK	CD2	161	P06729
KLTAGHLEELHEKQK	GVINP1	1356	Q7Z2Y8
EEKHQLFLQLKKVLH	GPS2	81	Q13227
LNHILQESKKLGKAL	C8orf34	226	Q49A92
DHKEPKKLAGVHALQ	AXIN2	746	Q9Y2T1
KKLLLHHANIESANK	ANKRD26P1	166	Q6NSI1
KRESLLHEGLPKNHK	BEST1	416	O76090
LHEGLPKNHKAAKQN	BEST1	421	O76090
HNLQIHAGDILKFLK	AMZ2	146	Q86W34
HIEKEILNNHGKSKT	CGAS	381	Q8N884
SKKKNLHLELEALNG	ITSN2	486	Q9NZM3
KVLKLQHENHALLSN	MTCL1	711	Q9Y4B5
QKKLHGLQAILVHEA	NUP210	836	Q8TEM1
LHNAASKLHKLKSEG	KIDINS220	726	Q9ULH0
DSGNELLKHLLKNKK	KMT2C	3771	Q8NEZ4
EEHKNLKLQQHVDKL	KIF15	736	Q9NS87
LSAKEDNHAPHLKQK	SBF2	686	Q86WG5
GHHQLQIAKKLSKGI	LRRK1	1466	Q38SD2
IKKKDLHHSNGEEKA	GALNT2	51	Q10471
HELEKENLQLKSKLH	CCDC88C	381	Q9P219
KRKHLLKHQSLGAAA	CUEDC1	336	Q9NWM3
LSDHKLHSRLNAQKK	MYLK4	361	Q86YV6
ELHRKLHSQGVLKNK	TUBGCP3	76	Q96CW5
HLEKLHEANNELQKK	HOOK3	551	Q86VS8
KKNSILLHKVQHDLN	HCN4	716	Q9Y3Q4
QLDRSIKGLKEHFHK	EXOC7	226	Q9UPT5
KASLAFLQKHLGLHK	PLA2G7	386	Q13093
LKSQHEELKKQHSDL	GOLIM4	121	O00461
NETDIKHLRKLKHPN	MAP3K13	201	O43283
IDIQHLAGKLKQHIE	APOB	2276	P04114
KHLDESHLLKGDKNL	KDM3A	176	Q9Y4C1
KREHHIEQLNDKLSK	CENPF	576	P49454
LANHQLDKEKAELIH	CEP290	2346	O15078
LKKLLETHIHNQGLA	CUL1	336	Q13616
LALVGKAHALKHKVE	CYGB	106	Q8WWM9
HNSVKKQLHLKLATG	GARIN6	131	Q8NEG0
KHGFNLLAKLKSHIQ	EPS8	336	Q12929
HTLQNHSVKEKGKLL	CCDC168	6536	Q8NDH2
DHIQNGKLDLTKLKH	DDX21	321	Q9NR30
LSLQHEGLKELIHKQ	SLFN13	416	Q68D06
LEKHEGKHQKLLLAV	MSH2	421	P43246
NLLSDHAKEKGKLHK	ERMAP	196	Q96PL5
LQLRKHDHKTNKKDG	SLITRK4	666	Q8IW52
KGGQLLVSLKNHHKT	UTP15	236	Q8TED0
HKLTKAEKLQLLNHR	CRCP	76	O75575
LQDKDLKEIGHHLKK	SH3GL3	146	Q99963
VKIGKEKLAHGHLKQ	SYNE2	4751	Q8WXH0
KPTDKHKTDLNHENL	CKM	101	P06732
LKIHEKQNGHIKFLT	SEC11B	86	P0C7V7
KHLLGKEAIKQRHLQ	FASTKD3	606	Q14CZ7
HLKGAHSKNLFLKDK	PRORSD1P	41	A6NEY8
LLHNKQEGRDHDKSK	SEMG1	106	P04279
SEKQLKHQVDHQKEL	SPDL1	126	Q96EA4
EHKGKLKTDSLQRLH	SHPRH	1056	Q149N8
KKLEELHHKLQELNA	PKN2	91	Q16513
SNLGKKIHDHAQLLS	ADAMDEC1	296	O15204
LAELHQEHDLKLNLK	CNOT1	1266	A5YKK6
NKKGKALLHQLESLA	TRIM24	321	O15164
LSGQSHLAIKDDKKH	TLE1	171	Q04724
NLENLKNLHKKRHHL	ZWILCH	181	Q9H900
KANLNVHLRKHTGEK	ZFAT	311	Q9P243
TLKSHKLLHTADGKQ	ZFAT	951	Q9P243
FNRHLKNKHGLKVVE	ZFAT	1056	Q9P243
GLKKHRLAHKAENLG	ZNF865	1031	P0CJ78
PLDLKIHKRNHTGEK	ZNF791	396	Q3KP31
QKRLLEHQKVHTGEK	ZNF549	541	Q6P9A3
NEKKIHLLNTKLEHV	SMC1B	231	Q8NDV3
AGILHHLNQKATKKG	SLC1A4	471	P43007
QLLLQHGADVHAKDK	TNKS	386	O95271
HKLIKGIHQSTIDLK	TRIM25	331	Q14258
TDLNQHKKIHTGEKL	ZNF721	586	Q8TF20
KLQAKHDLLQKTLGE	SRGAP2	466	O75044
KNLIAHVKGHKDNED	ZNF292	696	O60281
LTHHKGVNLTDIKLN	TMPRSS5	156	Q9H3S3
LVKKQLKKHLSGEEH	RRP36	151	Q96EU6
LKKHLSGEEHEKLQQ	RRP36	156	Q96EU6
AAQLKHHSENKGLDK	VAMP7	111	P51809
HQLLHDKGKSIQDLR	PTHLH	41	P12272
SQLKIKELDHNISKH	SMC2	906	O95347
KINHHDKINGKRKTA	NPIPB2	146	A6NJ64
QGVKAKSSLLIHKHL	ZDHHC11	311	Q9H8X9
HQDNQDKLKIIKRGH	ZNF84	91	P51523
LKTHAKEHKNLAEAL	YME1L1	736	Q96TA2
LHQRIHSGLKGNKKD	ZNF445	446	P59923
SLLIKLHHKLSGKQN	UBR3	1091	Q6ZT12
SQLKEHSLKVHGKAL	ZNF462	2096	Q96JM2
QSSNLIKHKKIHTGE	ZNF85	241	Q03923
HHKLPTDQLDLKKQQ	PLEKHG7	276	Q6ZR37
GLLLHKKALEHKATS	SNAPC4	1316	Q5SXM2
KEKSALINHRKIHSG	ZNF304	261	Q9HCX3
KKSLDLNVHKIIHSG	ZNF355P	301	Q9NSJ1
KLTLIKHQRAHAGGK	ZNF875	591	P10072
ADKGLKAPEQHLKHV	ZFAND4	431	Q86XD8
NHLESHKLINKVDKT	ZNF711	431	Q9Y462
AHKAEKKLQNIDHPL	SEMA6D	846	Q8NFY4
HQLLKKHLDTFLKGK	TPMT	46	P51580
IGHLKTLKELNVAHN	TLR4	146	O00206
SSDLNKHKRIHIGQK	ZNF486	446	Q96H40
SSLELHKQVHLGKKS	ZNF235	276	Q14590
LLNTDLHGHVNIGKK	PSD3	686	Q9NYI0
KHEKKLLKSQGRHLH	UNCX	206	A6NJT0
HEKFNKSLGHGLINK	WDR36	411	Q8NI36
KSGLIRHQKIHSGEK	ZNF649	386	Q9BS31
KHKKAALLLDHPNGD	NFKB1	636	P19838