Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	PLXNA3 CCR10 GPR12 DRD2 DRD3 OR4N2 GPR65 GPR35 NTSR1 GPR78 MC5R GPR135 NRG2 GPR183 PLXND1 ADGRV1 PTPRU ABCA7 EDNRA EDNRB CELSR2 PTPRG NRXN2 LMBR1L OR51I2 CD44 S1PR4	4.06e-05	1353	173	27	GO:0004888
GeneOntologyMolecularFunction	ATPase-coupled intramembrane lipid transporter activity	ATP8B3 ABCA12 ABCA7 ATP10D	9.47e-05	28	173	4	GO:0140326
GeneOntologyMolecularFunction	dopamine neurotransmitter receptor activity, coupled via Gi/Go	DRD2 DRD3	2.23e-04	3	173	2	GO:0001591
GeneOntologyMolecularFunction	endothelin receptor activity	EDNRA EDNRB	2.23e-04	3	173	2	GO:0004962
GeneOntologyMolecularFunction	amino-acid betaine transmembrane transporter activity	SLC22A4 SLC22A5	4.43e-04	4	173	2	GO:0015199
GeneOntologyMolecularFunction	phosphoric ester hydrolase activity	PDE6A INPP5D PTPRU TDP2 EDNRA PTPN13 PTPRG SBF1 NT5DC2 PDXP ILKAP	5.64e-04	386	173	11	GO:0042578
GeneOntologyMolecularFunction	SUMO ligase activity	RGPD4 RGPD8 RGPD3	6.54e-04	20	173	3	GO:0061665
GeneOntologyMolecularFunction	G protein-coupled receptor activity	CCR10 GPR12 DRD2 DRD3 OR4N2 GPR65 GPR35 NTSR1 GPR78 MC5R GPR135 GPR183 ADGRV1 EDNRA EDNRB CELSR2 OR51I2 S1PR4	6.83e-04	884	173	18	GO:0004930
GeneOntologyMolecularFunction	dopamine neurotransmitter receptor activity	DRD2 DRD3	7.34e-04	5	173	2	GO:0004952
GeneOntologyBiologicalProcess	learning	DRD2 DRD3 NTSR1 ABCA7 SHANK3 NRXN2 UBA6 PRKAR2B TANC1 LRRN4 CTNND2	1.55e-06	212	170	11	GO:0007612
GeneOntologyBiologicalProcess	negative regulation of adenylate cyclase activity	DRD2 DRD3 ADGRV1 EDNRB	1.25e-05	18	170	4	GO:0007194
GeneOntologyBiologicalProcess	negative regulation of cyclase activity	DRD2 DRD3 ADGRV1 EDNRB	1.57e-05	19	170	4	GO:0031280
GeneOntologyBiologicalProcess	NLS-bearing protein import into nucleus	RGPD4 RGPD8 RGPD3 RGPD5	1.95e-05	20	170	4	GO:0006607
GeneOntologyBiologicalProcess	negative regulation of lyase activity	DRD2 DRD3 ADGRV1 EDNRB	2.90e-05	22	170	4	GO:0051350
GeneOntologyBiologicalProcess	positive regulation of glucokinase activity	RGPD4 RGPD8 RGPD3	4.46e-05	9	170	3	GO:0033133
GeneOntologyBiologicalProcess	regulation of catecholamine uptake involved in synaptic transmission	NAT8L DRD2 DRD3	4.46e-05	9	170	3	GO:0051940
GeneOntologyBiologicalProcess	regulation of dopamine uptake involved in synaptic transmission	NAT8L DRD2 DRD3	4.46e-05	9	170	3	GO:0051584
GeneOntologyBiologicalProcess	positive regulation of hexokinase activity	RGPD4 RGPD8 RGPD3	6.33e-05	10	170	3	GO:1903301
GeneOntologyBiologicalProcess	learning or memory	DRD2 DRD3 NTSR1 ABCA7 SHANK3 NRXN2 UBA6 SLC17A7 PRKAR2B TANC1 LRRN4 CTNND2	6.48e-05	373	170	12	GO:0007611
GeneOntologyBiologicalProcess	regulation of adenylate cyclase activity	DRD2 DRD3 ADGRV1 EDNRA EDNRB	1.25e-04	59	170	5	GO:0045761
GeneOntologyBiologicalProcess	regulation of glucokinase activity	RGPD4 RGPD8 RGPD3	1.48e-04	13	170	3	GO:0033131
GeneOntologyBiologicalProcess	catecholamine uptake involved in synaptic transmission	NAT8L DRD2 DRD3	1.48e-04	13	170	3	GO:0051934
GeneOntologyBiologicalProcess	dopamine uptake involved in synaptic transmission	NAT8L DRD2 DRD3	1.48e-04	13	170	3	GO:0051583
GeneOntologyBiologicalProcess	negative regulation of cell development	SEMA3F PLXNA3 DRD3 INPP5D ZBTB7B EDNRB RGMA TMEM98 CD44 SOCS1 LOXL3	1.73e-04	353	170	11	GO:0010721
GeneOntologyBiologicalProcess	auditory behavior	DRD2 SHANK3 NRXN2	1.87e-04	14	170	3	GO:0031223
GeneOntologyBiologicalProcess	regulation of hexokinase activity	RGPD4 RGPD8 RGPD3	1.87e-04	14	170	3	GO:1903299
GeneOntologyBiologicalProcess	negative regulation of CD8-positive, alpha-beta T cell differentiation	ZBTB7B SOCS1	2.02e-04	3	170	2	GO:0043377
GeneOntologyBiologicalProcess	cognition	DRD2 DRD3 NTSR1 ABCA7 SHANK3 NRXN2 UBA6 SLC17A7 PRKAR2B TANC1 LRRN4 CTNND2	2.10e-04	423	170	12	GO:0050890
GeneOntologyBiologicalProcess	regulation of cyclase activity	DRD2 DRD3 ADGRV1 EDNRA EDNRB	2.63e-04	69	170	5	GO:0031279
GeneOntologyCellularComponent	cytoplasmic periphery of the nuclear pore complex	RGPD4 RGPD8 RGPD3	3.08e-05	8	174	3	GO:1990723
GeneOntologyCellularComponent	nuclear pore cytoplasmic filaments	RGPD4 RGPD8 RGPD3	6.52e-05	10	174	3	GO:0044614
GeneOntologyCellularComponent	annulate lamellae	RGPD4 RGPD8 RGPD3	1.93e-04	14	174	3	GO:0005642
GeneOntologyCellularComponent	cell projection membrane	DRD2 EVC2 PDE6A PLXND1 ADGRV1 ABCA7 SHANK3 SLC22A5 CD44 PDXP CEACAM20 CNGA2	2.74e-04	431	174	12	GO:0031253
GeneOntologyCellularComponent	nuclear pore nuclear basket	RGPD4 RGPD8 RGPD3	4.22e-04	18	174	3	GO:0044615
GeneOntologyCellularComponent	nuclear inclusion body	RGPD4 RGPD8 RGPD3	5.82e-04	20	174	3	GO:0042405
GeneOntologyCellularComponent	SUMO ligase complex	RGPD4 RGPD8 RGPD3	6.75e-04	21	174	3	GO:0106068
GeneOntologyCellularComponent	lamellipodium membrane	PLXND1 CD44 PDXP	7.77e-04	22	174	3	GO:0031258
GeneOntologyCellularComponent	inclusion body	RGPD4 RGPD8 TDP2 RGPD3 CABIN1	9.37e-04	90	174	5	GO:0016234
Domain	TPR-like_helical_dom	RGPD4 RGPD8 ST7 LONRF1 SNX21 TTC34 FBXO9 SPATA16 RGPD3 TRAPPC10 TANC1 CABIN1 RGPD5	2.56e-07	233	172	13	IPR011990
Domain	Grip	RGPD4 RGPD8 RGPD3 RGPD5	2.18e-06	11	172	4	SM00755
Domain	GRIP	RGPD4 RGPD8 RGPD3 RGPD5	2.18e-06	11	172	4	PF01465
Domain	Ran_BP1	RGPD4 RGPD8 RGPD3 RGPD5	3.25e-06	12	172	4	PF00638
Domain	RANBD1	RGPD4 RGPD8 RGPD3 RGPD5	3.25e-06	12	172	4	PS50196
Domain	GRIP_dom	RGPD4 RGPD8 RGPD3 RGPD5	3.25e-06	12	172	4	IPR000237
Domain	GRIP	RGPD4 RGPD8 RGPD3 RGPD5	3.25e-06	12	172	4	PS50913
Domain	RanBD	RGPD4 RGPD8 RGPD3 RGPD5	4.65e-06	13	172	4	SM00160
Domain	Ran_bind_dom	RGPD4 RGPD8 RGPD3 RGPD5	4.65e-06	13	172	4	IPR000156
Domain	TPR-contain_dom	RGPD4 RGPD8 LONRF1 TTC34 FBXO9 RGPD3 TANC1 CABIN1 RGPD5	1.06e-05	150	172	9	IPR013026
Domain	TPR_REGION	RGPD4 RGPD8 LONRF1 TTC34 FBXO9 RGPD3 TANC1 CABIN1 RGPD5	2.26e-05	165	172	9	PS50293
Domain	TPR	RGPD4 RGPD8 LONRF1 TTC34 FBXO9 RGPD3 TANC1 CABIN1 RGPD5	2.26e-05	165	172	9	PS50005
Domain	-	RGPD4 RGPD8 ST7 LONRF1 SNX21 TTC34 SPATA16 RGPD3 TANC1 CABIN1	2.27e-05	207	172	10	1.25.40.10
Domain	Rab_bind	RGPD4 RGPD8 RGPD3	2.61e-05	7	172	3	PF16704
Domain	GCC2_Rab_bind	RGPD4 RGPD8 RGPD3	2.61e-05	7	172	3	IPR032023
Domain	ARM-type_fold	DOCK3 ZYG11A GBF1 COPG1 IPO4 RYR3 RIF1 URB1 RNPEP LTN1 INTS4 CTNND2	7.43e-05	339	172	12	IPR016024
Domain	7TM_GPCR_Srsx	GPR12 DRD2 DRD3 MC5R GPR183 EDNRB OR51I2	8.00e-05	112	172	7	SM01381
Domain	Endthln_rcpt	EDNRA EDNRB	8.43e-05	2	172	2	IPR000499
Domain	-	RGPD4 RGPD8 RGPD3	8.78e-05	10	172	3	1.10.220.60
Domain	TPR	RGPD4 RGPD8 LONRF1 TTC34 RGPD3 TANC1 CABIN1	1.94e-04	129	172	7	SM00028
Domain	TPR_repeat	RGPD4 RGPD8 LONRF1 TTC34 RGPD3 TANC1 CABIN1	2.34e-04	133	172	7	IPR019734
Domain	GPCR_Rhodpsn_7TM	CCR10 GPR12 DRD2 DRD3 OR4N2 GPR65 GPR35 NTSR1 GPR78 MC5R GPR135 GPR183 EDNRA EDNRB OR51I2 S1PR4	4.79e-04	670	172	16	IPR017452
Domain	7tm_1	CCR10 GPR12 DRD2 DRD3 OR4N2 GPR65 GPR35 NTSR1 GPR78 MC5R GPR135 GPR183 EDNRA EDNRB OR51I2 S1PR4	5.36e-04	677	172	16	PF00001
Domain	G_PROTEIN_RECEP_F1_1	CCR10 GPR12 DRD2 DRD3 OR4N2 GPR65 GPR35 NTSR1 GPR78 MC5R GPR135 GPR183 EDNRA EDNRB OR51I2 S1PR4	6.08e-04	685	172	16	PS00237
Domain	G_PROTEIN_RECEP_F1_2	CCR10 GPR12 DRD2 DRD3 OR4N2 GPR65 GPR35 NTSR1 GPR78 MC5R GPR135 GPR183 EDNRA EDNRB OR51I2 S1PR4	6.68e-04	691	172	16	PS50262
Domain	GPCR_Rhodpsn	CCR10 GPR12 DRD2 DRD3 OR4N2 GPR65 GPR35 NTSR1 GPR78 MC5R GPR135 GPR183 EDNRA EDNRB OR51I2 S1PR4	6.78e-04	692	172	16	IPR000276
Domain	Dopamine_rcpt	DRD2 DRD3	8.28e-04	5	172	2	IPR000929
Pathway	WP_GPCRS_OTHER	DRD3 NTSR1 GPR135 GPR183 ADGRV1 EDNRA CELSR2	2.61e-05	93	132	7	M39629
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	DOCK3 SEMA3F PLXNA3 GBF1 SPOUT1 LONRF1 NTSR1 MED14 PLXND1 TESK1 ABCA7 RGMA URB1 CELSR2 SBF1 KBTBD11 EHMT1 WDR90 TANC1 UBE3C CABIN1 CHPF RGL2 PLK3	2.15e-09	1105	176	24	35748872
Pubmed	Complex genomic rearrangements lead to novel primate gene function.	RGPD4 RGPD8 RGPD3 RGPD5	2.19e-08	7	176	4	15710750
Pubmed	Endothelin ETB receptor heterodimerization: beyond the ETA receptor.	DRD3 EDNRA EDNRB	1.27e-07	3	176	3	18756291
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	RGPD4 ILF2 RGPD8 SPTBN2 CAMSAP3 DGKZ IPO4 SHANK3 ITIH4 CELSR2 SBF1 RGPD3 DZIP3 EHMT1 UBA6 PRKAR2B CTNND2 CABIN1 FBXO45	4.96e-07	963	176	19	28671696
Pubmed	Transcriptomic analysis and novel insights into lens fibre cell differentiation regulated by Gata3.	ATP10D EDNRB RYR3 CRYGA	2.31e-06	19	176	4	31847788
Pubmed	Interconversion of red opsin isoforms by the cyclophilin-related chaperone protein Ran-binding protein 2.	RGPD4 RGPD8 RGPD3	4.39e-06	7	176	3	9037092
Pubmed	Genomic organization, expression, and localization of murine Ran-binding protein 2 (RanBP2) gene.	RGPD4 RGPD8 RGPD3	4.39e-06	7	176	3	11353387
Pubmed	Microglial activation in an amyotrophic lateral sclerosis-like model caused by Ranbp2 loss and nucleocytoplasmic transport impairment in retinal ganglion neurons.	RGPD4 RGPD8 RGPD3	4.39e-06	7	176	3	30944974
Pubmed	Nucleoporin Nup358 drives the differentiation of myeloid-biased multipotent progenitors by modulating HDAC3 nuclear translocation.	RGPD4 RGPD8 RGPD3	4.39e-06	7	176	3	38838144
Pubmed	Retina-specifically expressed novel subtypes of bovine cyclophilin.	RGPD4 RGPD8 RGPD3	4.39e-06	7	176	3	7559465
Pubmed	Mst1, RanBP2 and eIF4G are new markers for in vivo PI3K activation in murine and human prostate.	RGPD4 RGPD8 RGPD3	4.39e-06	7	176	3	17372272
Pubmed	Proteostatic Remodeling of Small Heat Shock Chaperones─Crystallins by Ran-Binding Protein 2─and the Peptidyl-Prolyl cis-trans Isomerase and Chaperone Activities of Its Cyclophilin Domain.	RGPD4 RGPD8 RGPD3	4.39e-06	7	176	3	38657106
Pubmed	Nup358, a nucleoporin, functions as a key determinant of the nuclear pore complex structure remodeling during skeletal myogenesis.	RGPD4 RGPD8 RGPD3	4.39e-06	7	176	3	21205196
Pubmed	Haploinsufficiency of RanBP2 is neuroprotective against light-elicited and age-dependent degeneration of photoreceptor neurons.	RGPD4 RGPD8 RGPD3	4.39e-06	7	176	3	18949001
Pubmed	Selective impairment of a subset of Ran-GTP-binding domains of ran-binding protein 2 (Ranbp2) suffices to recapitulate the degeneration of the retinal pigment epithelium (RPE) triggered by Ranbp2 ablation.	RGPD4 RGPD8 RGPD3	4.39e-06	7	176	3	25187515
Pubmed	Localization of the Ran-GTP binding protein RanBP2 at the cytoplasmic side of the nuclear pore complex.	RGPD4 RGPD8 RGPD3	4.39e-06	7	176	3	8603673
Pubmed	Uncoupling phototoxicity-elicited neural dysmorphology and death by insidious function and selective impairment of Ran-binding protein 2 (Ranbp2).	RGPD4 RGPD8 RGPD3	4.39e-06	7	176	3	26632511
Pubmed	Differential loss of prolyl isomerase or chaperone activity of Ran-binding protein 2 (Ranbp2) unveils distinct physiological roles of its cyclophilin domain in proteostasis.	RGPD4 RGPD8 RGPD3	4.39e-06	7	176	3	24403063
Pubmed	Distinct and atypical intrinsic and extrinsic cell death pathways between photoreceptor cell types upon specific ablation of Ranbp2 in cone photoreceptors.	RGPD4 RGPD8 RGPD3	4.39e-06	7	176	3	23818861
Pubmed	Kinesin-1 and mitochondrial motility control by discrimination of structurally equivalent but distinct subdomains in Ran-GTP-binding domains of Ran-binding protein 2.	RGPD4 RGPD8 RGPD3	4.39e-06	7	176	3	23536549
Pubmed	Identification of RanBP2- and kinesin-mediated transport pathways with restricted neuronal and subcellular localization.	RGPD4 RGPD8 RGPD3	4.39e-06	7	176	3	12191015
Pubmed	Ranbp2 haploinsufficiency mediates distinct cellular and biochemical phenotypes in brain and retinal dopaminergic and glia cells elicited by the Parkinsonian neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).	RGPD4 RGPD8 RGPD3	4.39e-06	7	176	3	22821000
Pubmed	Neuroprotection resulting from insufficiency of RANBP2 is associated with the modulation of protein and lipid homeostasis of functionally diverse but linked pathways in response to oxidative stress.	RGPD4 RGPD8 RGPD3	4.39e-06	7	176	3	20682751
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	COPG1 RBBP5 MED14 MCM6 IPO4 RNPEP FDFT1 NT5DC2 LTN1 EHMT1 INTS4 PRKAR2B FBXW11	6.20e-06	560	176	13	35241646
Pubmed	The nucleoporin RanBP2 tethers the cAMP effector Epac1 and inhibits its catalytic activity.	RGPD4 RGPD8 RGPD3	7.00e-06	8	176	3	21670213
Pubmed	The RacGAP β2-Chimaerin selectively mediates axonal pruning in the hippocampus.	SEMA3F PLXNA3 SLC17A7	7.00e-06	8	176	3	22726444
Pubmed	Critical role of RanBP2-mediated SUMOylation of Small Heterodimer Partner in maintaining bile acid homeostasis.	RGPD4 RGPD8 RGPD3	7.00e-06	8	176	3	27412403
Pubmed	Mice lacking Ran binding protein 1 are viable and show male infertility.	RGPD4 RGPD8 RGPD3	7.00e-06	8	176	3	21310149
Pubmed	The distribution of phosphorylated SR proteins and alternative splicing are regulated by RANBP2.	RGPD4 RGPD8 RGPD3	7.00e-06	8	176	3	22262462
Pubmed	Pharmacogenetics and olanzapine treatment: CYP1A2*1F and serotonergic polymorphisms influence therapeutic outcome.	DRD2 HTRA1 DRD3	7.00e-06	8	176	3	19636338
Pubmed	Zap70 and downstream RanBP2 are required for the exact timing of the meiotic cell cycle in oocytes.	RGPD4 RGPD8 RGPD3	7.00e-06	8	176	3	28745977
Pubmed	Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIalpha.	RGPD4 RGPD8 RGPD3	1.05e-05	9	176	3	18394993
Pubmed	Loss of Ranbp2 in motoneurons causes disruption of nucleocytoplasmic and chemokine signaling, proteostasis of hnRNPH3 and Mmp28, and development of amyotrophic lateral sclerosis-like syndromes.	RGPD4 RGPD8 RGPD3	1.05e-05	9	176	3	28100513
Pubmed	Association of the kinesin-binding domain of RanBP2 to KIF5B and KIF5C determines mitochondria localization and function.	RGPD4 RGPD8 RGPD3	1.05e-05	9	176	3	17887960
Pubmed	The docking of kinesins, KIF5B and KIF5C, to Ran-binding protein 2 (RanBP2) is mediated via a novel RanBP2 domain.	RGPD4 RGPD8 RGPD3	1.05e-05	9	176	3	11553612
Pubmed	The zinc finger cluster domain of RanBP2 is a specific docking site for the nuclear export factor, exportin-1.	RGPD4 RGPD8 RGPD3	1.05e-05	9	176	3	10601307
Pubmed	The cyclophilin-like domain mediates the association of Ran-binding protein 2 with subunits of the 19 S regulatory complex of the proteasome.	RGPD4 RGPD8 RGPD3	1.05e-05	9	176	3	9733766
Pubmed	Impairments in age-dependent ubiquitin proteostasis and structural integrity of selective neurons by uncoupling Ran GTPase from the Ran-binding domain 3 of Ranbp2 and identification of novel mitochondrial isoforms of ubiquitin-conjugating enzyme E2I (ubc9) and Ranbp2.	RGPD4 RGPD8 RGPD3	1.05e-05	9	176	3	28877029
Pubmed	Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.	ATP6V1B2 HTRA1 CAMSAP3 MYO18A DGKZ ADGRV1 SHANK3 PTPN13 SBF1 ACAN TRAPPC10	1.34e-05	430	176	11	32581705
Pubmed	The RanBP2/RanGAP1*SUMO1/Ubc9 SUMO E3 ligase is a disassembly machine for Crm1-dependent nuclear export complexes.	RGPD4 RGPD8 RGPD3	1.49e-05	10	176	3	27160050
Pubmed	Parkin ubiquitinates and promotes the degradation of RanBP2.	RGPD4 RGPD8 RGPD3	1.49e-05	10	176	3	16332688
Pubmed	Cyclophilin-related protein RanBP2 acts as chaperone for red/green opsin.	RGPD4 RGPD8 RGPD3	1.49e-05	10	176	3	8857542
Pubmed	Ran-dependent docking of importin-beta to RanBP2/Nup358 filaments is essential for protein import and cell viability.	RGPD4 RGPD8 RGPD3	1.49e-05	10	176	3	21859863
Pubmed	A directed protein interaction network for investigating intracellular signal transduction.	PLXNA3 SPOUT1 COPG1 RBBP5 MARS1 CAMSAP3 DGKZ DCK TDP2 URB1 SBF1 NRXN2 TMEM98 WFIKKN1 SGSM3 CTNND2 C8orf33 FBXW11	1.77e-05	1124	176	18	21900206
Pubmed	RanBP2 modulates Cox11 and hexokinase I activities and haploinsufficiency of RanBP2 causes deficits in glucose metabolism.	RGPD4 RGPD8 RGPD3	2.04e-05	11	176	3	17069463
Pubmed	An Rtn4/Nogo-A-interacting micropeptide modulates synaptic plasticity with age.	RGPD4 RGPD8 RGPD3	2.04e-05	11	176	3	35771867
Pubmed	T-cell receptor (TCR) signaling promotes the assembly of RanBP2/RanGAP1-SUMO1/Ubc9 nuclear pore subcomplex via PKC-θ-mediated phosphorylation of RanGAP1.	RGPD4 RGPD8 RGPD3	2.04e-05	11	176	3	34110283
Pubmed	N-linked Glycosylation on the N-terminus of the dopamine D2 and D3 receptors determines receptor association with specific microdomains in the plasma membrane.	DRD2 DRD3	2.55e-05	2	176	2	25289757
Pubmed	Haplotype in the IBD5 region is associated with refractory Crohn's disease in Slovenian patients and modulates expression of the SLC22A5 gene.	SLC22A4 SLC22A5	2.55e-05	2	176	2	21695374
Pubmed	Dopamine receptor D2 and D3 gene variants are not associated with the antidepressant effect of total sleep deprivation in bipolar depression.	DRD2 DRD3	2.55e-05	2	176	2	12834818
Pubmed	Mapping the landscape of human dopamine D2/3 receptors with [11C]raclopride.	DRD2 DRD3	2.55e-05	2	176	2	31444615
Pubmed	Analysis of the influence of OCTN1/2 variants within the IBD5 locus on disease susceptibility and growth indices in early onset inflammatory bowel disease.	SLC22A4 SLC22A5	2.55e-05	2	176	2	16469794
Pubmed	Homology modeling of dopamine D2 and D3 receptors: molecular dynamics refinement and docking evaluation.	DRD2 DRD3	2.55e-05	2	176	2	22970199
Pubmed	Association of novelty seeking scores and striatal dopamine D₂/D₃ receptor availability of healthy volunteers: single photon emission computed tomography with ¹²³i-iodobenzamide.	DRD2 DRD3	2.55e-05	2	176	2	20970071
Pubmed	Palmitoylation on the carboxyl terminus tail is required for the selective regulation of dopamine D2 versus D3 receptors.	DRD2 DRD3	2.55e-05	2	176	2	27349735
Pubmed	Gene expression of carnitine organic cation transporters 1 and 2 (OCTN) is downregulated in patients with ulcerative colitis.	SLC22A4 SLC22A5	2.55e-05	2	176	2	21910182
Pubmed	Association of SLC22A4/5 polymorphisms with steroid responsiveness of inflammatory bowel disease in Japan.	SLC22A4 SLC22A5	2.55e-05	2	176	2	18274826
Pubmed	Endothelin receptor heteromerization inhibits β-arrestin function in HEK293 cells.	EDNRA EDNRB	2.55e-05	2	176	2	32744876
Pubmed	Identification of a novel role for endothelins within the oviduct.	EDNRA EDNRB	2.55e-05	2	176	2	20357223
Pubmed	Expression of endothelin receptors in frog, chicken, mouse and human pigment cells.	EDNRA EDNRB	2.55e-05	2	176	2	16962346
Pubmed	The expression of endothelin type A and B receptors in the lateral wall of the mouse cochlea.	EDNRA EDNRB	2.55e-05	2	176	2	17607529
Pubmed	Association study of dopamine D2, D3 receptor gene polymorphisms with motor fluctuations in PD.	DRD2 DRD3	2.55e-05	2	176	2	11425949
Pubmed	Cortical dopamine D2/D3 receptors and verbal memory in man.	DRD2 DRD3	2.55e-05	2	176	2	20188195
Pubmed	Influence of WFIKKN1 on BMP1-mediated activation of latent myostatin.	BMP1 WFIKKN1	2.55e-05	2	176	2	27782377
Pubmed	Substrate discrimination by ergothioneine transporter SLC22A4 and carnitine transporter SLC22A5: gain-of-function by interchange of selected amino acids.	SLC22A4 SLC22A5	2.55e-05	2	176	2	19814996
Pubmed	DRD3 (dopamine receptor D3) but not DRD2 activates autophagy through MTORC1 inhibition preserving protein synthesis.	DRD2 DRD3	2.55e-05	2	176	2	31538542
Pubmed	Striatal dopamine D₂/D₃ receptor binding in pathological gambling is correlated with mood-related impulsivity.	DRD2 DRD3	2.55e-05	2	176	2	22776462
Pubmed	A COPI coat subunit interacts directly with an early-Golgi localized Arf exchange factor.	GBF1 COPG1	2.55e-05	2	176	2	19039328
Pubmed	Association study of tardive dyskinesia and twelve DRD2 polymorphisms in schizophrenia patients.	DRD2 DRD3	2.55e-05	2	176	2	16959057
Pubmed	Fluorescent ligands for dopamine D2/D3 receptors.	DRD2 DRD3	2.55e-05	2	176	2	33318558
Pubmed	[123I]epidepride binding to cerebellar dopamine D2/D3 receptors is displaceable: implications for the use of cerebellum as a reference region.	DRD2 DRD3	2.55e-05	2	176	2	17175177
Pubmed	Expression of endothelin receptor subtypes in bronchial tumors.	EDNRA EDNRB	2.55e-05	2	176	2	20043107
Pubmed	Modulation of endothelin receptors in the failing right ventricle of the heart and vasculature of the lung in human pulmonary arterial hypertension.	EDNRA EDNRB	2.55e-05	2	176	2	24582810
Pubmed	Dopamine D2 (DAD2) and dopamine D3 (DAD3) receptor gene polymorphisms and treatment outcome in alcohol dependence.	DRD2 DRD3	2.55e-05	2	176	2	12811641
Pubmed	Functional diversity of endothelin pathways in human lung fibroblasts may be based on structural diversity of the endothelin receptors.	EDNRA EDNRB	2.55e-05	2	176	2	14636059
Pubmed	Otoprotective effects of mouse nerve growth factor in DBA/2J mice with early-onset progressive hearing loss.	CDH23 FSCN2	2.55e-05	2	176	2	28345280
Pubmed	Oxaliplatin transport mediated by organic cation/carnitine transporters OCTN1 and OCTN2 in overexpressing human embryonic kidney 293 cells and rat dorsal root ganglion neurons.	SLC22A4 SLC22A5	2.55e-05	2	176	2	21606177
Pubmed	Transport of ipratropium, an anti-chronic obstructive pulmonary disease drug, is mediated by organic cation/carnitine transporters in human bronchial epithelial cells: implications for carrier-mediated pulmonary absorption.	SLC22A4 SLC22A5	2.55e-05	2	176	2	20020740
Pubmed	Association Study Between DRD2, DRD3 Genetic Polymorphisms and Adverse Reactions in Chinese Patients on Amisulpride Treatment.	DRD2 DRD3	2.55e-05	2	176	2	39187246
Pubmed	Endothelin ETA and ETB receptor expression in the human trigeminal ganglion.	EDNRA EDNRB	2.55e-05	2	176	2	16816835
Pubmed	Dopamine D2/3 Binding Potential Modulates Neural Signatures of Working Memory in a Load-Dependent Fashion.	DRD2 DRD3	2.55e-05	2	176	2	30478031
Pubmed	Association between migraine and endothelin type A receptor (ETA -231 A/G) gene polymorphism.	EDNRA EDNRB	2.55e-05	2	176	2	11376172
Pubmed	Molecular characterization and regulation of the human endothelin receptors.	EDNRA EDNRB	2.55e-05	2	176	2	8440682
Pubmed	Altered expression and signal transduction of endothelin-1 receptors in heritable and idiopathic pulmonary arterial hypertension.	EDNRA EDNRB	2.55e-05	2	176	2	22688668
Pubmed	ETA and ETB receptors are expressed in vascular adventitial fibroblasts.	EDNRA EDNRB	2.55e-05	2	176	2	21949113
Pubmed	Association study of dopamine D2 and D3 receptor gene polymorphisms with cocaine dependence.	DRD2 DRD3	2.55e-05	2	176	2	16094250
Pubmed	Endothelin antagonism in portal hypertensive mice: implications for endothelin receptor-specific signaling in liver disease.	EDNRA EDNRB	2.55e-05	2	176	2	19299580
Pubmed	Extrastriatal dopamine D 2/3 receptor density and distribution in drug-naive schizophrenic patients.	DRD2 DRD3	2.55e-05	2	176	2	12740603
Pubmed	Striatal and extrastriatal D2/D3-receptor-binding properties of ziprasidone: a positron emission tomography study with [18F]Fallypride and [11C]raclopride (D2/D3-receptor occupancy of ziprasidone).	DRD2 DRD3	2.55e-05	2	176	2	19011428
Pubmed	Mice lacking dopamine D2 and D3 receptors exhibit differential activation of prefrontal cortical neurons during tasks requiring attention.	DRD2 DRD3	2.55e-05	2	176	2	15537671
Pubmed	Elevation of blood pressure by genetic and pharmacological disruption of the ETB receptor in mice.	EDNRA EDNRB	2.55e-05	2	176	2	10198387
Pubmed	Association of the organic cation transporter OCTN genes with Crohn's disease in the Spanish population.	SLC22A4 SLC22A5	2.55e-05	2	176	2	16333318
Pubmed	Association of DRD2 and DRD3 polymorphisms with Parkinson's disease in a multiethnic consortium.	DRD2 DRD3	2.55e-05	2	176	2	21663922
Pubmed	Increased gene expression and production of murine endothelin receptors after birth.	EDNRA EDNRB	2.55e-05	2	176	2	12763050
Pubmed	[Molecular cloning of human endothelin receptors and their expression in vascular endothelial cells and smooth muscle cells].	EDNRA EDNRB	2.55e-05	2	176	2	1291713
Pubmed	Frontal D2/3 Receptor Availability in Schizophrenia Patients Before and After Their First Antipsychotic Treatment: Relation to Cognitive Functions and Psychopathology.	DRD2 DRD3	2.55e-05	2	176	2	26819282
Pubmed	Association of the OCTN1/1672T variant with increased risk for colorectal cancer in young individuals and ulcerative colitis patients.	SLC22A4 SLC22A5	2.55e-05	2	176	2	21793125
Pubmed	Association of the DRD2 and DRD3 polymorphisms with response to pramipexole in Parkinson's disease patients.	DRD2 DRD3	2.55e-05	2	176	2	19396436
Pubmed	Dopamine D2/3 receptor availability and amphetamine-induced dopamine release in obesity.	DRD2 DRD3	2.55e-05	2	176	2	24785761
Pubmed	Potentiation of the D2 mutant motor phenotype in mice lacking dopamine D2 and D3 receptors.	DRD2 DRD3	2.55e-05	2	176	2	10391470
GeneFamily	Tetratricopeptide repeat domain containing\|Bardet-Biedl syndrome associated\|BBSome	RGPD4 RGPD8 SNX21 TTC34 RGPD3 TANC1 RGPD5	1.22e-05	115	121	7	769
GeneFamily	G protein-coupled receptors, Class A orphans	GPR12 GPR65 GPR35 GPR78 GPR135 GPR183	1.38e-05	78	121	6	262
GeneFamily	Endothelin receptors	EDNRA EDNRB	4.44e-05	2	121	2	225
GeneFamily	Dopamine receptors	DRD2 DRD3	4.38e-04	5	121	2	181
GeneFamily	Plexins	PLXNA3 PLXND1	1.55e-03	9	121	2	683
ToppCell	droplet-Marrow-BM-1m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CAPN12 SLC16A13 EVA1C LRIG3 PTPN13 SLC22A5 TRPM1 UBE3C	3.65e-07	168	176	8	2e88d9cb7c80a4656fab290db8b45a5a0599d769
ToppCell	droplet-Liver-LIVER-NPC-1m-Endothelial-Hepatocyte_(Pericentral)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3F RHOD LONRF1 PLXND1 SHANK3 PTPRG CABIN1 S1PR4	4.98e-07	175	176	8	98dc3b6f69a29d587f503898f09912700950e3d9
ToppCell	droplet-Kidney-KIDNEY-30m-Lymphocytic-Epcam____proximal_tube_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CAPN12 KIAA0232 GPR183 PACS1 URB1 PDXP UBE3C	3.23e-06	158	176	7	1d78578dc1f8ba43dacdccae1082c0b9d749f64d
ToppCell	normal-na-Lymphocytic-lymphocyte-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	MCM6 TTC34 TESK1 HPS3 EVA1C BMP1 MTX3	8.77e-06	184	176	7	2c286712428662bc4589dc5ac4011bf7ed403cb5
ToppCell	CV-Moderate-7\|CV / Virus stimulation, Condition and Cluster	KNTC1 GBF1 ANKRD36C NBAS URB1 MTX3 XYLB	9.41e-06	186	176	7	8571956890fc9894d766ba294a28e376b4aba428
ToppCell	facs-Aorta-Heart-3m-Endothelial-aorta_endothelial_cell\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3F TCN2 PLXND1 PTPRU EDNRB PTPRG EXOC3L4	1.28e-05	195	176	7	3969b8d5fcec8ef1831531a781f7bbcebab5a4ba
ToppCell	COVID-19_Severe-Neu_4\|COVID-19_Severe / 5 Neutrophil clusters in COVID-19 patients	KNTC1 PIWIL4 ANKRD36C FBXO9 KBTBD11 ANKRD18A OTULINL	1.41e-05	198	176	7	bfdddddef9f3f0eb6af013873dec4e06b7c78c58
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ST7 NR6A1 ADGRV1 BMP1 FREM2 PTPN13 VKORC1L1	1.46e-05	199	176	7	8587bd98de7767a575088afbea07a1feb4516b9b
ToppCell	COVID-19_Severe-Neu_4\|World / 5 Neutrophil clusters in COVID-19 patients	KNTC1 PIWIL4 ANKRD36C FBXO9 KBTBD11 ANKRD18A OTULINL	1.46e-05	199	176	7	0e327479bbda5a16643cf317d293a2918d619f87
ToppCell	VE-CD8-memory_CD4\|VE / Condition, Cell_class and T cell subcluster	CAMSAP3 DCST2 RYR3 PACS1 CD44 SLC17A7	3.18e-05	152	176	6	9401b7770c1bdc87eba25e82922f5dd1c4fa37ee
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D122\|Adult / Lineage, Cell type, age group and donor	CAPN12 CAMSAP3 ADGRV1 PTPN13 FCGBP PTPRG	3.81e-05	157	176	6	31d1bd9138c60e8485664ec4144f987226e3eef9
ToppCell	Club_cells-Donor_01\|World / lung cells shred on cell class, cell subclass, sample id	DCST2 RGMA TMEM98 NT5DC2 HEY2 CTNND2	4.24e-05	160	176	6	b261a3a49c850d92bc9e04fc3527c752dfe37a1a
ToppCell	IIF-Lymphocyte-T_NK-NK_CD56bright\|IIF / Disease, Lineage and Cell Type	CAPN12 GPR65 INPP5D SHANK3 CD44 SOCS1	4.39e-05	161	176	6	b1bd1074ecba4cf171d748e2f686e9a99c0f0e89
ToppCell	droplet-Heart-nan-18m-Mesenchymal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EVC2 GPR135 ADGRV1 PTPN13 SLC22A4 PRKAR2B	5.20e-05	166	176	6	9adceb746e67e955fd8b3e0984f4eed44b64a270
ToppCell	5'-Parenchyma_lung-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.0.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NAT8L PDE6A GPR65 GPR35 CD44 SOCS1	5.38e-05	167	176	6	0aa1973141a2437df24c9857cd50ff3dfc7673c0
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sncg-Sncg_Gpr50\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	KNTC1 ATP8B3 DRD2 PIWIL4 EVA1C	5.56e-05	103	176	5	d8965b338b90ddc0686ea0d94e9a330128566c39
ToppCell	facs-Lung-18m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l5\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PDE6A GPR183 KBTBD11 SOCS1 TRPM1 OTULINL	5.94e-05	170	176	6	67e78e3c1d4cd3c6eaa5d0a9785b6cd8a3b08039
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Myeloid-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR35 CDH23 SBF1 LTN1 CD44 S1PR4	5.94e-05	170	176	6	f3d5678669dcaed1836014cea543758b7ccc6b46
ToppCell	facs-Marrow-T-cells-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCR10 CDH23 PTPRU WDR90 TANC1 FBXO45	6.13e-05	171	176	6	913bae728b5e653771a27c79a309eb023699f1d0
ToppCell	facs-Marrow-T-cells-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCR10 CDH23 PTPRU WDR90 TANC1 FBXO45	6.13e-05	171	176	6	f28b2336057e353b96a6ff4581ec9fd0ca0789d9
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RHOD C8orf48 SNX21 LTN1 PLEKHM3 OTULINL	6.33e-05	172	176	6	7fb31ccbcd0204c3612986a6bc20d57ed6825e9c
ToppCell	facs-Skin-nan-24m-Epithelial-epidermal_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NAT8L ABCA12 SPTBN2 RDH12 PDXP ALOX12	6.33e-05	172	176	6	5ca89af7406e7e1a055dd60d6f89615f69e62324
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RHOD C8orf48 SNX21 LTN1 PLEKHM3 OTULINL	6.33e-05	172	176	6	2a4614b3d25e8c6b095e6992d8ca35371dcdb5e1
ToppCell	facs-Marrow-B-cells-18m-Hematologic-Unknown_Progenitor\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCR10 NAT8L EVC2 CDH23 HEY2 CHPF	7.19e-05	176	176	6	5f9ae5eb45603ed0422a3a993ecdbe2ce05d6e45
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADGRV1 ANKRD36C URB1 PRKAA2 UBA6 TANC1	7.90e-05	179	176	6	6e965e424eebef50f0202cff75f458be395cfca1
ToppCell	facs-Heart-RA-24m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCR10 ITIH4 EDNRA RGMA EVA1C HEY2	7.90e-05	179	176	6	d76a05f1fee7f2f7b7b7994d3622e96f02b49432
ToppCell	facs-Heart-RA-24m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCR10 ITIH4 EDNRA RGMA EVA1C HEY2	7.90e-05	179	176	6	6be47c877250968a916c711ba0787eb7b4c5443d
ToppCell	wk_20-22-Hematologic-Myeloid-aDC_2\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	ATP6V1B2 GPR183 NR6A1 HPS1 CD44 TNFAIP8	8.39e-05	181	176	6	8f7e5c310f4cdc4b2fb54fea950d01e56bd298e1
ToppCell	facs-Trachea-18m-Hematologic\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GPR65 INPP5D GPR183 TNFAIP8 OTULINL S1PR4	8.65e-05	182	176	6	a72b200488d212f1783233a94fc9a9596269f284
ToppCell	PND01-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DGKZ MCM6 DCK VKORC1L1 CD44 PLET1	8.65e-05	182	176	6	57f8b8d7b132f3ad6f2b1e79c3812fe938657d2c
ToppCell	5'-Adult-LymphNode-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SEMA3F TCN2 CDH23 PLXND1 SHANK3 EVA1C	8.92e-05	183	176	6	a644258ba90acc62d571623e429d72ffc4b69203
ToppCell	P28-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	EDNRA NT5DC2 SLC35F6 PRKAR2B LOXL3 OTULINL	9.19e-05	184	176	6	23c24ab5786af33d605bc445d06117b9da6c6331
ToppCell	droplet-Lung-LUNG-30m-Myeloid-Proliferating_Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MCM6 WFIKKN1 PLET1 PRKAR2B WDR90 SIGLEC1	9.19e-05	184	176	6	16aa8e88bdd51b1d132d5cf33c29963b384a8bae
ToppCell	facs-Heart-RA-24m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KNTC1 PDE6A EDNRA NRXN2 SLC35F6 HEY2	9.47e-05	185	176	6	c4ef8d9f8b9769e887daac4efd9dc05738b28ae2
ToppCell	CV-Moderate-7\|Moderate / Virus stimulation, Condition and Cluster	KNTC1 GBF1 NBAS URB1 MTX3 XYLB	9.47e-05	185	176	6	a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCell	facs-Heart-RA-24m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KNTC1 PDE6A EDNRA NRXN2 SLC35F6 HEY2	9.47e-05	185	176	6	10ddf38d908525b4258f9d2da8be4c56ebc08ff4
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-Pericytes-Immature_pericyte\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CCR10 EDNRA PTPRG NT5DC2 ACAN HEY2	9.75e-05	186	176	6	db4d9ac89cc1e55062ba888b3410b773340595dd
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-BM_CD8_+_CD4_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR183 KBTBD11 SOCS1 TRPM1 OTULINL CHPF	9.75e-05	186	176	6	4dce1484653bb266e2305cbb306fb11eaf7892e2
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NAT8L HTRA1 EDNRB PTPN13 KLHDC7A CTNND2	9.75e-05	186	176	6	ac7a84b11b4550c4ac01eab370dc8ab88e4fb72b
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-mature_alpha-beta_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR183 KBTBD11 SOCS1 TRPM1 OTULINL CHPF	9.75e-05	186	176	6	e23e1246914e230369a716d0d666b98383bf8512
ToppCell	facs-Trachea-3m-Endothelial-endothelial_cell_of_trachea\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SEMA3F PLXND1 SHANK3 EDNRB LIPE PTPRG	1.03e-04	188	176	6	20072a2a3f9ecbe727c850629f19420cf60e4bc5
ToppCell	facs-Tongue-nan-24m-Epithelial-suprabasal\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NAT8L TCN2 ABCA12 SPTBN2 RDH12 CELSR2	1.03e-04	188	176	6	ed35e438796cef302b6787c111753425922792dc
ToppCell	3'-Adult-LargeIntestine-Hematopoietic-Myeloid-Mast_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DRD2 GPR65 GPR183 CD44 SOCS1 TNFAIP8	1.03e-04	188	176	6	3fe9d698ff8f540edebf8609e7d42d3f81271edb
ToppCell	facs-Trachea-3m-Endothelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SEMA3F PLXND1 SHANK3 EDNRB LIPE PTPRG	1.03e-04	188	176	6	dd817059e1b4225e84733559f7839cc973b7dfd6
ToppCell	PCW_13-14-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	DOCK3 ADGRV1 FREM2 FCGBP PRKAA2 CTNND2	1.03e-04	188	176	6	0d86044bc340e3efb90d0022dd299873639d831c
ToppCell	COPD-Epithelial-ATII\|COPD / Disease state, Lineage and Cell class	ADGRV1 BMP1 FREM2 PTPN13 PTPRG TANC1	1.03e-04	188	176	6	eb6d79d733b53f64ca615bb777c64ed456866549
ToppCell	facs-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SEMA3F PLXND1 SHANK3 EDNRB LIPE PTPRG	1.03e-04	188	176	6	6ab5ce8569f896a0fe7a76b8b4a83661e5499b8c
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	HTRA1 NRG2 GPR183 EDNRB RYR3 OTULINL	1.06e-04	189	176	6	b6d5dec55bf352f6ae19d8f488ae70aa10fb9a8f
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	HTRA1 NRG2 GPR183 TERF1 EDNRB RYR3	1.06e-04	189	176	6	da9ecc0d7b81c1901f30f97bb44112dc85444a66
ToppCell	T_cells-Effector_memory_CD4+_T_cells\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	GPR183 PLXND1 PTPN13 CD44 SOCS1 PLK3	1.10e-04	190	176	6	1af91fe0ee2c924e12f4db93c793e7af475d8f80
ToppCell	facs-Aorta-Heart-3m-Mesenchymal-fibroblast\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HTRA1 BMP1 PTPN13 LOXL3 LRRN4 CHPF	1.13e-04	191	176	6	9214655dca96d766737c9f30b624d7fe7050342e
ToppCell	CD8+_Memory_T_cell-CV-7\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	KNTC1 GBF1 ANKRD36C NBAS URB1 XYLB	1.13e-04	191	176	6	9454f642c3621370fa23640b631301346b300950
ToppCell	Control-Stromal-SMC\|Stromal / Disease state, Lineage and Cell class	SEMA3F ITIH4 EDNRA EDNRB PRKAA2 TNFAIP8	1.13e-04	191	176	6	2da83c493e60ad0278848957645277d76737a188
ToppCell	ASK454-Epithelial-Secretory\|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq	EVC2 MAD2L1BP URB1 LIPE TANC1 S1PR4	1.13e-04	191	176	6	c63c781e7e93265e591cf494cb4ce8ed797c24fb
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CCR10 GPR78 EDNRA NT5DC2 ACAN HEY2	1.16e-04	192	176	6	71863f18a82394ed9f8e5ec8a4017215382a8284
ToppCell	facs-Aorta-Heart-3m\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3F MYO18A PTPRU EDNRB RIF1 PTPRG	1.16e-04	192	176	6	1ccc47792edf9ee23501c8e2165d11271636b66a
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	INPP5D NRG2 DGKZ PLXND1 SHANK3 RYR3	1.16e-04	192	176	6	c0e59e642b42c055cf73d029cf54d07d9b719359
ToppCell	PND01-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SEMA3F TCN2 SHANK3 EDNRB PTPRG S1PR4	1.19e-04	193	176	6	b6b065b0c2ad31d1488dfa970450b29a8ac1f3aa
ToppCell	PND01-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SEMA3F TCN2 SHANK3 EDNRB PTPRG S1PR4	1.19e-04	193	176	6	4513e6cb3f86d9cc56e7892fbe11a861335bd179
ToppCell	PND01-Endothelial-Endothelial_blood-vessel-Microvascular_EC\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SEMA3F TCN2 SHANK3 EDNRB PTPRG S1PR4	1.19e-04	193	176	6	30254658a2023ea9808cdd786530b966a1446418
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	INPP5D NRG2 DGKZ PLXND1 SHANK3 RYR3	1.19e-04	193	176	6	52e918884877b6659cdca0496390e440f73694a9
ToppCell	PCW_10-12-Endothelial-Endothelial_mature-endo_venous_(13)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	SEMA3F TCN2 INPP5D PLXND1 SHANK3 EVA1C	1.23e-04	194	176	6	efd5efed060edb7f24d59600981bb60ec28ac2ef
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ST7 ADGRV1 BMP1 FREM2 PTPN13 PTPRG	1.23e-04	194	176	6	97534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCell	IPF-Endothelial-VE_Venous\|Endothelial / Disease state, Lineage and Cell class	TCN2 CDH23 ATP10D PTPN13 PTPRG S1PR4	1.23e-04	194	176	6	e8a9005963704286bcc50785bda8d7d63ec001b1
ToppCell	3'-Adult-LargeIntestine-Hematopoietic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GPR65 INPP5D GPR183 SOCS1 TNFAIP8 S1PR4	1.26e-04	195	176	6	38ed4f48d450119cd50d6b85bd2d966a39d02c6b
ToppCell	facs-Bladder-nan-3m-Epithelial-bladder_mesenchymal_cell_(Car3+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HTRA1 MC5R EDNRA SOCS1 OTULINL CHPF	1.26e-04	195	176	6	18b01ab63ee1deae3cf29669d66fff9ca4efc5c4
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PLXND1 SHANK3 RYR3 EVA1C LIPE PTPRG	1.33e-04	197	176	6	cd509e49bbdbf991cc5913960ff3ef275ad40628
ToppCell	10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-osteochondral_precursor\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	EDNRA PTPN13 PTPRG TMEM98 HEY2 TANC1	1.33e-04	197	176	6	c165c6fd12dc649b39e920d8528e2eb65c61956b
ToppCell	10x5'v1-week_12-13-Mesenchymal_osteo-stroma-osteoblast_precursor\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	PTPRG TMEM98 ACAN HEY2 TANC1 CHPF	1.33e-04	197	176	6	2f72fd9a5b6d62c24a95ed2246194ea7458c0f12
ToppCell	mLN-(2)_B_cell-(20)_B_cell_IgA_Plasma\|mLN / shred on region, Cell_type, and subtype	KNTC1 CCR10 TCN2 NT5DC2 CTNND2 CHPF	1.33e-04	197	176	6	a39b384ee9824a08c3b544a9c3c7f0f95f08d6a7
ToppCell	kidney_cells-Adult_normal_reference-Immune-Lymphocytic_T/NK-T_Cell-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GPR65 GPR183 CD44 SOCS1 TNFAIP8 S1PR4	1.33e-04	197	176	6	4326e8a4b6b51cac222e5a247545dc524098fc6e
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PLXND1 SHANK3 RYR3 EVA1C LIPE PTPRG	1.33e-04	197	176	6	412cb5f37df57121ddd1492021445479c7cbccbf
ToppCell	kidney_cells-Adult_normal_reference-Immune-Lymphocytic_T/NK-T_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GPR65 GPR183 CD44 SOCS1 TNFAIP8 S1PR4	1.33e-04	197	176	6	037096303e3cbbea39b30e414ab95187fc990ee5
ToppCell	mLN-B_cell-B_cell_IgA_Plasma\|mLN / Region, Cell class and subclass	KNTC1 CCR10 TCN2 NT5DC2 CTNND2 CHPF	1.33e-04	197	176	6	20822fce311326765b71337ce501ba44ea14f58f
ToppCell	10x5'v1-week_14-16-Myeloid_neutrophil-granulo-eo/baso/mast\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	CAPN12 GPR65 GPR183 ATP10D RYR3 CD44	1.37e-04	198	176	6	2e6630eab77b12a6059682ab5ba465f38e469102
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar-AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NR6A1 ADGRV1 BMP1 FREM2 PTPN13 PTPRG	1.37e-04	198	176	6	f948391296c261c473d339069a6d0f20ccd6f38f
ToppCell	distal-2-Hematologic-OLR1+_Classical_Monocyte\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ATP6V1B2 GPR35 NTSR1 GPR183 CD44 TNFAIP8	1.37e-04	198	176	6	43179d92e45b14f6f3d63949a9d88c2c7531f7d1
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	ST7 NR6A1 ADGRV1 PTPN13 PTPRG TANC1	1.37e-04	198	176	6	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	NS-moderate-d_16-33-Myeloid-Non-resident_Macrophage\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ATP6V1B2 GPR183 PLXND1 EDNRB CD44 SIGLEC1	1.37e-04	198	176	6	11a7a553de6786c1e8288251ba0d5c898505c158
ToppCell	droplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3F KNTC1 PTPRG FSCN2 RGL2	1.39e-04	125	176	5	35042ed43045dddc341b76cc5f9fe31b5ba0abb8
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ST7 NR6A1 ADGRV1 FREM2 PTPN13 VKORC1L1	1.41e-04	199	176	6	725610310e5c5fd7120c0be9acb55bf152026ddd
ToppCell	10x5'v1-week_12-13-Mesenchymal_osteo-stroma\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	BMP1 TMEM98 ACAN HEY2 TANC1 CHPF	1.41e-04	199	176	6	d65ee89d5c7e8ed693d58e6a6de09565840e11c5
ToppCell	mLN-B_cell-B_cell_IgA_Plasma\|B_cell / Region, Cell class and subclass	CCR10 TCN2 NT5DC2 PRKAR2B CTNND2 CHPF	1.41e-04	199	176	6	09494953bc7fff63cf2763ea89fca7abb97c186f
ToppCell	Parenchymal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ST7 NR6A1 ADGRV1 FREM2 PTPN13 VKORC1L1	1.41e-04	199	176	6	5cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCell	control-Epithelial-Secretory\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	LRIG3 RIF1 PTPN13 PRKAA2 CD44 PRKAR2B	1.41e-04	199	176	6	262e5b8a52c8ddb0b47048c786e8bdb7158e1b9a
ToppCell	moderate-Myeloid-Non-resident_Macrophage\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	ATP6V1B2 GPR183 PLXND1 EDNRB CD44 SIGLEC1	1.41e-04	199	176	6	614c1e788d89310e78984241977941beed8d12dc
ToppCell	10x5'v1-week_12-13-Mesenchymal_osteo\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	BMP1 TMEM98 ACAN HEY2 TANC1 CHPF	1.41e-04	199	176	6	bf138cc692df727e087d140c014149ee5da00d9d
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW12-Macroglial-Astrocyte\|GW12 / Sample Type, Dataset, Time_group, and Cell type.	CDH23 RDH12 EVA1C FREM2 PTPN13 LOXL3	1.45e-04	200	176	6	b9bd6c4381c92bfc1bfff9aa778a62a41d08f1ef
ToppCell	Parenchymal-10x3prime_v2-Stromal-Peri/Epineurial_-NAF_epineurial\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	CAPN12 SNX21 RGMA PRKAA2 DZIP3 TRAPPC10	1.45e-04	200	176	6	be46efc899d06c55ee297bee3126f69bcdb2048b
ToppCell	TCGA-Thymus-Primary_Tumor-Thymoma-Type_B3\|TCGA-Thymus / Sample_Type by Project: Shred V9	ZYG11A GPR35 C8orf48 RNPEP SLC22A5	1.61e-04	129	176	5	c760a1f9b86f086074e6e04e50ab40da3639e5fb
ToppCell	E18.5-samps-Mesenchymal-Matrix_fibroblast-matrix_-_mature_2\|E18.5-samps / Age Group, Lineage, Cell class and subclass	NRG2 ZBTB7B PDXP SOCS1 TNFAIP8	1.73e-04	131	176	5	f2eee150f5cff852e8f52f09b35e26f17d80833b
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE-P1-Tnr-Polydendrocyte.Tnr.Pdgfa-Pik3r3_(Pdgfa)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	NAT8L PIWIL4 FCGBP WFIKKN1	1.79e-04	71	176	4	2220e1b02baa71961cfc85536bafeb313e588bf3
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE-P1-Tnr-Polydendrocyte.Tnr.Pdgfa-Pik3r3_(Pdgfa)-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	NAT8L PIWIL4 FCGBP WFIKKN1	1.79e-04	71	176	4	cc5de8bbcfefa2bf93cc137c74b49a745d5da229
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Fezf2-Excitatory_Neuron.Slc17a7-Slc17a8.Fezf2-Slc17a8_(Layer_5,_Retrosplenial_cortex_(RSG)_and_Subiculum,_Tshz2+)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	ATP8B3 ABCA12 SIGLEC1 CNGA2	1.89e-04	72	176	4	e3f4d1df43cc41b0424f27485a00ddca9e905f95
Computational	GPCR signaling pathways (immune and neuro).	DRD3 GPR65 NTSR1 GPR183 EDNRA EDNRB S1PR4	1.39e-05	90	95	7	MODULE_375
Computational	Genes in the cancer module 289.	DRD3 GPR65 NTSR1 GPR183 EDNRA EDNRB S1PR4	1.09e-04	124	95	7	MODULE_289
Computational	Genes in the cancer module 146.	DRD3 GPR65 GPR183 EDNRA EDNRB S1PR4	2.77e-04	102	95	6	MODULE_146
Drug	Adenosine 5'-monophosphate monohydrate [18422-05-4]; Up 200; 11uM; MCF7; HT_HG-U133A	SEMA3F DRD2 GBF1 EDNRA EDNRB URB1 ACAN SLC22A4 PRKAA2 PLK3	3.42e-06	198	176	10	3237_UP
Drug	A 86929	DRD2 DRD3 EDNRA EDNRB	4.41e-06	15	176	4	ctd:C095427
Drug	R)-3-pyrrolidinecarboxylic acid	DRD2 EDNRA EDNRB	8.93e-06	6	176	3	CID001501969
Drug	fenoldopam	DRD2 DRD3 EDNRA EDNRB RNPEP PRKAR2B	1.70e-05	70	176	6	CID000003340
Drug	Tetrahydrozoline hydrochloride [522-48-5]; Up 200; 16.8uM; MCF7; HT_HG-U133A	DRD2 GBF1 MARS1 PTPRU BMP1 PACS1 SBF1 HPS1 SGSM3	2.10e-05	194	176	9	6769_UP
Drug	Nicardipine hydrochloride [54527-84-3]; Up 200; 7.8uM; MCF7; HT_HG-U133A	SEMA3F DRD2 MARS1 GPR183 NR6A1 BMP1 SLC17A7 OTULINL ALOX12	2.47e-05	198	176	9	3215_UP
Drug	tolrestat	DOCK3 DRD2 DRD3 NTSR1 XYLB TNFAIP8	3.17e-05	78	176	6	CID000053359
Drug	sclerotiorin	ITIH4 EDNRA EDNRB	3.69e-05	9	176	3	CID006436015
Drug	Bosentan	EDNRA EDNRB	5.94e-05	2	176	2	DB00559
Drug	TAK 044	EDNRA EDNRB	5.94e-05	2	176	2	ctd:C088196
Drug	6-bromo-2,3-dihydrobenzofuran	EDNRA EDNRB	5.94e-05	2	176	2	CID011252616
Drug	Sulpiride	DRD2 DRD3	5.94e-05	2	176	2	DB00391
Drug	N-n-propyl-N-phenylethyl-4(3-hydroxyphenyl)ethylamine hydrochloride	DRD2 DRD3	5.94e-05	2	176	2	ctd:C016868
Drug	5-methoxy-1-methyl-2-(n-propylamino)tetralin	DRD2 DRD3	5.94e-05	2	176	2	ctd:C051171
Drug	CGS 15855A	DRD2 DRD3	5.94e-05	2	176	2	ctd:C051347
Drug	1H-Indene-2-carboxylic acid, 1-(1,3-benzodioxol-5-yl)-3-(2- (carboxymethoxy)-4-methoxyphenyl)-2,3-dihydro-5-propoxy-, (1S,2R,3S)-	EDNRA EDNRB	5.94e-05	2	176	2	ctd:C087551
Drug	(5,6-dimethoxyindan-2-yl)dipropylamine	DRD2 DRD3	5.94e-05	2	176	2	ctd:C086335
Drug	IRL 1620	EDNRA EDNRB	5.94e-05	2	176	2	ctd:C074308
Drug	Domperidone	DRD2 DRD3	5.94e-05	2	176	2	DB01184
Drug	enrasentan	EDNRA EDNRB	5.94e-05	2	176	2	ctd:C098288
Drug	PD 145065	EDNRA EDNRB	5.94e-05	2	176	2	ctd:C082887
Drug	LU 224332	EDNRA EDNRB	5.94e-05	2	176	2	ctd:C113044
Drug	UH 232	DRD2 DRD3	5.94e-05	2	176	2	ctd:C045971
Drug	4,4a,5,6,7,8,8a,9-octahydro-5-propyl-1H-pyrzolo(3,4-g)quinoline	DRD2 DRD3	5.94e-05	2	176	2	ctd:C416545
Drug	3-(3-cyanophenyl)-N-n-propylpiperidine	DRD2 DRD3	5.94e-05	2	176	2	ctd:C094012
Drug	iodosulpride	DRD2 DRD3	5.94e-05	2	176	2	ctd:C045105
Drug	fluoroclebopride	DRD2 DRD3	5.94e-05	2	176	2	ctd:C083673
Drug	Sitaxentan	EDNRA EDNRB	5.94e-05	2	176	2	DB06268
Drug	A 182086	EDNRA EDNRB	5.94e-05	2	176	2	ctd:C467893
Drug	PD 156252	EDNRA EDNRB	5.94e-05	2	176	2	ctd:C106950
Drug	GR 218231	DRD2 DRD3	5.94e-05	2	176	2	ctd:C408390
Drug	L-671,776	EDNRA EDNRB	5.94e-05	2	176	2	CID000122853
Drug	N-(4-(2-(4-(3-cyano-5-trifluoromethylphenyl)piperazin-1-yl)ethyl)cyclohexyl)-3-pyridinesulfonic amide	DRD2 DRD3	5.94e-05	2	176	2	ctd:C539157
Drug	Piribedil	DRD2 DRD3	5.94e-05	2	176	2	ctd:D010891
Drug	tezosentan	EDNRA EDNRB	5.94e-05	2	176	2	ctd:C120582
Drug	AC1L31N6	DRD2 DRD3	5.94e-05	2	176	2	CID000132830
Drug	spirodihydrobenzofuranlactam VI	EDNRA EDNRB	5.94e-05	2	176	2	CID000469820
Drug	J 104132	EDNRA EDNRB	5.94e-05	2	176	2	ctd:C119319
Drug	phenylethylamine	GPR12 DRD2 DRD3 ADGRV1 EDNRA LOXL3	6.69e-05	89	176	6	CID000001001
Drug	6-Br-APB	DRD2 DRD3 RNPEP	7.16e-05	11	176	3	CID000005016
Drug	Li-7	DOCK3 ABCA12 BMP1 FDFT1	1.19e-04	33	176	4	CID000611002
Drug	5230742; Up 200; 17uM; MCF7; HT_HG-U133A_EA	PLXNA3 EDNRA BMP1 SBF1 ASB6 DZIP3 EHMT1 CABIN1	1.20e-04	190	176	8	970_UP
Drug	3-isoreserpine	DRD2 DRD3 ABCA12 ABCA7 EDNRA EDNRB RNPEP LOXL3	1.20e-04	190	176	8	CID000005052
Drug	Chlorprothixene hydrochloride [6469-93-8]; Up 200; 11.4uM; MCF7; HT_HG-U133A	SPTBN2 PTPRU ABCA7 EDNRA RIF1 ACAN SLC17A7 CTNND2	1.24e-04	191	176	8	2627_UP
Drug	Proadifen hydrochloride [62-68-0]; Up 200; 10.2uM; MCF7; HT_HG-U133A	SEMA3F MARS1 MED14 PTPRU URB1 CD44 XYLB CABIN1	1.24e-04	191	176	8	7165_UP
Drug	Niclosamide [50-65-7]; Down 200; 12.2uM; PC3; HT_HG-U133A	SEMA3F PLXNA3 SRD5A3 NTSR1 ABCA7 EDNRA SGSM3 ALOX12	1.29e-04	192	176	8	4018_DN
Drug	Carbimazole [22232-54-8]; Down 200; 21.4uM; MCF7; HT_HG-U133A	SEMA3F MARS1 PTPRU SBF1 HPS1 CTNND2 CABIN1 FBXW11	1.43e-04	195	176	8	5399_DN
Drug	Nafronyl oxalate [3200-06-4]; Up 200; 8.4uM; MCF7; HT_HG-U133A	SRD5A3 MED14 BMP1 PACS1 PTPRG HPS1 SGSM3 CABIN1	1.43e-04	195	176	8	5287_UP
Drug	Betamethasone [378-44-9]; Down 200; 10.2uM; PC3; HT_HG-U133A	SEMA3F SPTBN2 NTSR1 PLXND1 BMP1 PACS1 HPS1 CABIN1	1.48e-04	196	176	8	6728_DN
Drug	Palmatine chloride [3486-67-7]; Down 200; 10.4uM; MCF7; HT_HG-U133A	RHOD MARS1 NR6A1 PTPRU ASB6 HPS1 EHMT1 SGSM3	1.48e-04	196	176	8	2795_DN
Drug	genistein; Up 200; 10uM; MCF7; HT_HG-U133A	SEMA3F PLXNA3 NRG2 BMP1 PACS1 CELSR2 HPS1 PLK3	1.48e-04	196	176	8	5232_UP
Drug	Spaglumic acid [4910-46-7]; Down 200; 13.2uM; MCF7; HT_HG-U133A	SRD5A3 ST7 PLXND1 BMP1 URB1 ASB6 HEY2 TNFAIP8	1.53e-04	197	176	8	7465_DN
Drug	vinblastine sulfate; Up 200; 0.1uM; MCF7; HT_HG-U133A	MARS1 MED14 PLXND1 PACS1 TRAPPC10 TNFAIP8 CTNND2 CABIN1	1.53e-04	197	176	8	7551_UP
Drug	Mianserine hydrochloride [21535-47-7]; Down 200; 13.2uM; PC3; HT_HG-U133A	GBF1 RHOD MARS1 ATP10D FBXO9 DZIP3 SOCS1 SGSM3	1.59e-04	198	176	8	2068_DN
Drug	Morantel tartrate [26155-31-7]; Up 200; 10.8uM; PC3; HT_HG-U133A	SEMA3F NRG2 EDNRA BMP1 ACAN SLC35F6 OTULINL CABIN1	1.59e-04	198	176	8	1798_UP
Drug	Enalapril maleate [76095-16-4]; Up 200; 8.2uM; MCF7; HT_HG-U133A	MARS1 TESK1 PACS1 FBXO9 CD44 DZIP3 TNFAIP8 CTNND2	1.59e-04	198	176	8	7428_UP
Drug	(S)-(-)-Atenolol [93379-54-5]; Down 200; 15uM; MCF7; HT_HG-U133A	GBF1 MED14 TESK1 BMP1 PACS1 SLC22A4 TRAPPC10 CABIN1	1.59e-04	198	176	8	5325_DN
Drug	16-phenyl tetranor Prostaglandin E2; Up 200; 10uM; MCF7; HT_HG-U133A	GPR12 SRD5A3 ABCA12 MED14 CD44 DZIP3 SLC17A7 SGSM3	1.59e-04	198	176	8	7541_UP
Drug	Nimesulide [51803-78-2]; Up 200; 13uM; MCF7; HT_HG-U133A	ST7 PACS1 FBXO9 SBF1 SLC22A4 CD44 TRAPPC10 CTNND2	1.59e-04	198	176	8	7024_UP
Drug	Butamben [94-25-7]; Up 200; 20.6uM; MCF7; HT_HG-U133A	MARS1 URB1 ACAN PRKAA2 HEY2 SLC17A7 SIGLEC1 ALOX12	1.64e-04	199	176	8	6093_UP
Drug	CAY10397; Up 200; 10uM; MCF7; HT_HG-U133A	PLXNA3 ABCA12 MARS1 NR6A1 EDNRB RIF1 HEY2 CABIN1	1.70e-04	200	176	8	7082_UP
Drug	Ornidazole [16773-42-5]; Up 200; 18.2uM; MCF7; HT_HG-U133A	GBF1 NR6A1 LIPE HEY2 SLC17A7 XYLB SGSM3 PLK3	1.70e-04	200	176	8	2272_UP
Drug	(1-(2-(bis(4-fluorophenyl)methoxy)ethyl)-4-(3-hydroxy-3-phenylpropyl) piperazinyl decanoate)	DRD2 DRD3	1.77e-04	3	176	2	ctd:C461261
Drug	isodiospyrin	TOP1 ALOX12	1.77e-04	3	176	2	CID000099298
Drug	DP-6OH-3CA	DRD2 DRD3	1.77e-04	3	176	2	CID000086146
Drug	Neuriplege	DRD2 DRD3	1.77e-04	3	176	2	CID000065750
Drug	7-(N,N-dipropylamino)-5,6,7,8-tetrahydronaphtho(2,3-b)dihydro-2,3-furan	DRD2 DRD3	1.77e-04	3	176	2	ctd:C090812
Drug	E106E	EDNRA EDNRB	1.77e-04	3	176	2	CID000026761
Drug	pyrazolinone	EDNRA EDNRB	1.77e-04	3	176	2	CID000351317
Drug	7-hydroxy-2-N,N-dipropylaminotetralin	DRD2 DRD3	1.77e-04	3	176	2	ctd:C031349
Drug	ZD 2574	EDNRA EDNRB	1.77e-04	3	176	2	ctd:C415840
Drug	myriceric acid C	EDNRA EDNRB	1.77e-04	3	176	2	CID005274625
Drug	3-N-methylspiperone	DRD2 DRD3	1.77e-04	3	176	2	ctd:C039167
Drug	WS009A	EDNRA EDNRB	1.77e-04	3	176	2	CID000131948
Drug	Pd164333	EDNRA EDNRB	1.77e-04	3	176	2	CID005311351
Drug	quinelorane	DRD2 DRD3	1.77e-04	3	176	2	ctd:C047726
Drug	FLA908	DRD2 DRD3	1.77e-04	3	176	2	CID000129516
Drug	2-nitrobenzoyl chloride	EDNRA EDNRB	1.77e-04	3	176	2	CID000011875
Drug	SB-277011	DRD2 DRD3	1.77e-04	3	176	2	CID005311096
Drug	DCHAPS	DRD2 DRD3	1.77e-04	3	176	2	CID000129392
Drug	NSC-711994	ITIH4 FDFT1	1.77e-04	3	176	2	CID005471614
Drug	2-ethylacetanilide	EDNRA EDNRB	1.77e-04	3	176	2	CID000036332
Drug	nafadotride	DRD2 DRD3	1.77e-04	3	176	2	ctd:C097285
Drug	BP 897	DRD2 DRD3	1.77e-04	3	176	2	ctd:C120565
Drug	iodoethylspiperone	DRD2 DRD3	1.77e-04	3	176	2	CID000131222
Drug	NSC 90	EDNRA EDNRB	1.77e-04	3	176	2	CID000073811
Drug	TC-6	TCN2 ACAN EHMT1 SLC17A7	2.30e-04	39	176	4	CID000398799
Drug	(2S,3R)-Sphingosine	GPR12 GPR65 DGKZ ABCA7 RYR3 PRKAR2B TRPM1 SIGLEC1 SGSM3 TNFAIP8 S1PR4	2.33e-04	389	176	11	CID000001104
Drug	lergotrile	DRD2 DRD3 NTSR1	2.36e-04	16	176	3	CID000037586
Drug	fluanisone	DRD2 EDNRA RNPEP	2.36e-04	16	176	3	CID000015139
Disease	Disruptive, Impulse Control, and Conduct Disorders	DRD2 DRD3	9.29e-05	3	165	2	C0021122
Disease	Intermittent Explosive Disorder	DRD2 DRD3	9.29e-05	3	165	2	C0021776
Disease	sortilin measurement	ATXN7L2 CELSR2	1.85e-04	4	165	2	EFO_0600000
Disease	Disorder of eye	PDE6A CDH23 RDH12 ADGRV1 FREM2 FSCN2 TRPM1	1.99e-04	212	165	7	C0015397
Disease	Parkinson's disease (implicated_via_orthology)	DRD2 HTRA1 DRD3 FBXO9 PRKAA2 SLC17A7	2.63e-04	157	165	6	DOID:14330 (implicated_via_orthology)
Disease	hemojuvelin measurement	RGMA CELSR2	3.07e-04	5	165	2	EFO_0008148
Disease	heroin dependence (biomarker_via_orthology)	DRD2 DRD3	3.07e-04	5	165	2	DOID:9976 (biomarker_via_orthology)
Disease	BMI-adjusted waist-hip ratio, sex interaction measurement, age at assessment	ST7 PLXND1 DCST2 NT5DC2 TNFAIP8	3.17e-04	105	165	5	EFO_0007788, EFO_0008007, EFO_0008343
Disease	Coxsackievirus Infections	SLC22A4 SLC22A5	4.59e-04	6	165	2	C0010246
Disease	Myocarditis	SLC22A4 SLC22A5	4.59e-04	6	165	2	C0027059
Disease	Carditis	SLC22A4 SLC22A5	4.59e-04	6	165	2	C0869523
Disease	anxiety disorder (is_implicated_in)	DRD2 CTNND2	4.59e-04	6	165	2	DOID:2030 (is_implicated_in)
Disease	smoking behavior, BMI-adjusted waist circumference	DOCK3 NT5DC2 ACAN SLC22A4 FBXW11	6.30e-04	122	165	5	EFO_0004318, EFO_0007789
Disease	acetylcarnitine measurement	SLC22A4 SLC22A5	8.51e-04	8	165	2	EFO_0021038
Disease	butyrylcarnitine measurement	SLC22A4 SLC22A5	8.51e-04	8	165	2	EFO_0020010
Disease	repulsive guidance molecule A measurement	RGMA CELSR2	1.09e-03	9	165	2	EFO_0008273
Disease	velocardiofacial syndrome (implicated_via_orthology)	EDNRA TRAPPC10	1.09e-03	9	165	2	DOID:12583 (implicated_via_orthology)
Disease	nervonoylcarnitine (C24:1) measurement	SLC22A4 SLC22A5	1.09e-03	9	165	2	EFO_0800549
Disease	Recurrent depression	DRD2 DRD3	1.09e-03	9	165	2	C0221480
Disease	Hermanski-Pudlak Syndrome	HPS3 HPS1	1.36e-03	10	165	2	C0079504
Disease	Hermansky-Pudlak syndrome	HPS3 HPS1	1.36e-03	10	165	2	cv:C0079504
Disease	Nephroblastoma	TCN2 NBAS	1.36e-03	10	165	2	Orphanet_654
Disease	Delirium	DRD2 DRD3	1.36e-03	10	165	2	C0011206
Disease	smoking behavior, BMI-adjusted waist-hip ratio	PLXND1 DCST2 NT5DC2 TNFAIP8	1.40e-03	86	165	4	EFO_0004318, EFO_0007788
Disease	Schizophrenia	DRD2 DRD3 SPTBN2 NTSR1 GPR78 MC5R SHANK3 NRXN2 SLC17A7 TRPM1 CTNND2 FBXO45 ALOX12	1.45e-03	883	165	13	C0036341
Disease	obesity (biomarker_via_orthology)	DRD2 ITIH4 LIPE SOCS1 ALOX12	1.45e-03	147	165	5	DOID:9970 (biomarker_via_orthology)
Disease	lignoceroylcarnitine (C24) measurement	SLC22A4 SLC22A5	1.65e-03	11	165	2	EFO_0800541
Disease	Lenticulostriate Disorders	DRD2 DRD3	1.98e-03	12	165	2	C0750951
Disease	complement C1q tumor necrosis factor-related protein 1 measurement	CDH23 CELSR2	1.98e-03	12	165	2	EFO_0801493
Disease	Extrapyramidal Disorders	DRD2 DRD3	1.98e-03	12	165	2	C0015371
Disease	nicotine dependence (implicated_via_orthology)	DRD2 DRD3	1.98e-03	12	165	2	DOID:0050742 (implicated_via_orthology)
Disease	granulins measurement	CDH23 CELSR2	1.98e-03	12	165	2	EFO_0008141
Disease	tryptophan betaine measurement	SLC22A4 SLC22A5	1.98e-03	12	165	2	EFO_0021017
Disease	hexanoylcarnitine measurement	SLC22A4 SLC22A5	1.98e-03	12	165	2	EFO_0021040
Disease	Basal Ganglia Diseases	DRD2 DRD3	1.98e-03	12	165	2	C0004782
Disease	homostachydrine measurement	SLC22A4 SLC22A5	2.33e-03	13	165	2	EFO_0021164
Disease	male infertility (implicated_via_orthology)	TCTE1 SPATA16	2.33e-03	13	165	2	DOID:12336 (implicated_via_orthology)
Disease	dihomo-linolenoylcarnitine (C20:3n3 or 6) measurement	SLC22A4 SLC22A5	2.33e-03	13	165	2	EFO_0800547
Disease	cerotoylcarnitine (C26) measurement	SLC22A4 SLC22A5	2.33e-03	13	165	2	EFO_0800542
Disease	Pneumoconiosis	CDH23 ACAN	2.71e-03	14	165	2	C0032273
Disease	Bagassosis	CDH23 ACAN	2.71e-03	14	165	2	C0004681
Disease	Retinitis Pigmentosa	PDE6A RDH12 FSCN2 UBAP1L	2.81e-03	104	165	4	C0035334
Disease	ovarian carcinoma (is_implicated_in)	SOCS1 CABIN1	3.11e-03	15	165	2	DOID:4001 (is_implicated_in)
Disease	platelet storage pool deficiency (implicated_via_orthology)	HPS3 HPS1	3.11e-03	15	165	2	DOID:2223 (implicated_via_orthology)
Disease	Dyskinesia, Medication-Induced	DRD2 DRD3	3.11e-03	15	165	2	C0751088
Disease	Dyskinesia, Drug-Induced	DRD2 DRD3	3.11e-03	15	165	2	C0013386
Disease	Ciliopathies	EVC2 CDH23 RDH12 ADGRV1	3.44e-03	110	165	4	C4277690
Disease	Polyposis, Adenomatous Intestinal	ITIH4 CD44	3.54e-03	16	165	2	C2713442
Disease	Familial Intestinal Polyposis	ITIH4 CD44	3.54e-03	16	165	2	C2713443
Disease	Cannabis Dependence	DRD2 FDFT1	4.00e-03	17	165	2	C0006870
Disease	Adenomatous Polyposis Coli	ITIH4 CD44	4.00e-03	17	165	2	C0032580
Disease	bacteriemia	DOCK3 PTPRG	4.00e-03	17	165	2	EFO_0003033
Disease	Cocaine-Related Disorders	DRD2 DRD3 PRMT6 FDFT1	4.28e-03	117	165	4	C0236736
Disease	metabolite measurement	MCM6 ATP10D NBAS RNPEP SLC22A4 SLC22A5 HPS1 OTULINL CABIN1	4.41e-03	560	165	9	EFO_0004725
Disease	Schizophrenia	DRD3 SHANK3	4.48e-03	18	165	2	cv:C0036341
Disease	aspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement	PRMT6 PACS1 SYT16 PTPRG ACAN TNFAIP8 CCDC171	4.53e-03	364	165	7	EFO_0004612, EFO_0004696, EFO_0004735, EFO_0004736, EFO_0007800, EFO_0009946
Disease	low density lipoprotein cholesterol measurement, phospholipid measurement	CELSR2 SLC22A5 CEACAM20 TOP1	4.68e-03	120	165	4	EFO_0004611, EFO_0004639
Disease	hypertension (is_implicated_in)	DRD2 HTRA1 EDNRA LIPE	4.82e-03	121	165	4	DOID:10763 (is_implicated_in)
Disease	portal hypertension (implicated_via_orthology)	EDNRA EDNRB	4.99e-03	19	165	2	DOID:10762 (implicated_via_orthology)
Disease	oleoylcarnitine measurement	SLC22A4 SLC22A5	4.99e-03	19	165	2	EFO_0021043
Disease	Alopecia	HTRA1 EDNRA	4.99e-03	19	165	2	C0002170

Protein segments in the cluster

Peptide	Gene	Start	Entry
DSLYLFRVQAVCRND	PTPRG	416	P23470
YINACEELRTSLLSR	EXOC3L4	481	Q17RC7
LACISADRYVAIARA	CCR10	131	P46092
AEDYALCSDLRSIRQ	ANKRD18A	236	Q8IVF6
RRISTILFGAAYTCL	RNPEP	356	Q9H4A4
AYTCLEAATGRALLR	RNPEP	366	Q9H4A4
EALRALRAAAYSAQV	C8orf33	176	Q9H7E9
FCNLSLSERSRQSYL	ABCA12	621	Q86UK0
ARRLFQQILSAVDYC	PRKAA2	116	P54646
VASELGYFLCIRNAR	CEACAM20	461	Q6UY09
LYSRSCALSTQRDFL	CCDC171	741	Q6TFL3
ASVCSLLAITVDRYL	GPR12	126	P47775
ASRTLFYEILCSLIN	ADGRV1	5686	Q8WXG9
LRVYFSRCNSIRVDS	CRYGA	26	P11844
ITVLNLCALSVDRYR	EDNRA	171	P25101
SLCALSIDRYRAVAS	EDNRB	191	P24530
AFAQETLRTLCLAYR	ATP8B3	686	O60423
LLRFLLESGAAYNCS	ASB6	276	Q9NWX5
FLYILAARASCAAQR	CELSR2	2536	Q9HCU4
ILNFTSLDLYRSRLC	BMP1	361	P13497
LFRDSSCQFRALYTL	CAMSAP3	1161	Q9P1Y5
RETIAFYNLTICARD	CDH23	1811	Q9H251
CILRNLSYRLAAETS	CTNND2	766	Q9UQB3
YVFSRRLDRFCSALS	ATXN7L2	426	Q5T6C5
AALVYAARAYQCTLR	ATP10D	731	Q9P241
CYVDDVFLRVLSRSL	ABCA7	536	Q8IZY2
NVREAVSGRYSLFCL	ITIH4	401	Q14624
RALSELAALCYLIAF	RGPD5	311	Q99666
RALSELAALCYLIAF	RGPD8	311	O14715
VADFSATYLRCQLLL	INTS4	656	Q96HW7
IRSAYFELVSALCQR	LTN1	271	O94822
YCNRKRAELALSAFL	C8orf48	201	Q96LL4
DRCLYLLDRFAQAVT	ANKRD36C	431	Q5JPF3
ARELASRGARVYIAC	RDH12	56	Q96NR8
FRECLTEVARYLSSV	HEY2	126	Q9UBP5
RFCDDILSSYFRLSL	MTX3	231	Q5HYI7
FLFTYRDCLSLAAAI	TCTE1	261	Q5JU00
ASLRLGFSEYCRISN	MCM6	711	Q14566
SLCSLEFYRANDTAR	LOXL3	256	P58215
LSTAACLRRLFRAIF	MAD2L1BP	181	Q15013
FLRDACTYATALNVA	NTSR1	146	P30989
RVSYIADCAFRGLSS	LRIG3	346	Q6UXM1
RYREALAAACEALRA	LONRF1	226	Q17RB8
STTLRFYRNLNLEAC	FREM2	2621	Q5SZK8
RNAVCIFYLVLRALD	FDFT1	66	P37268
LIDYAARRLVACGSI	PLXNA3	101	P51805
AALCAFRFADVRAAI	PLXND1	386	Q9Y4D7
LLDFNRVSSVYEARC	KIAA0232	1331	Q92628
RLACADISINSIYGL	OR51I2	186	Q9H344
ASYAVILCRIRGSSS	OR4N2	216	Q8NGD1
NLTLFQAACRGYLAR	MYO18A	1191	Q92614
VRAFLNCDRYSVGLL	PDE6A	266	P16499
ATYRTTCQDFRILDR	KAT14	541	Q9H8E8
IAENILSYLDARSLC	FBXW11	131	Q9UKB1
IACLQYRDRLVVSGS	FBXW11	406	Q9UKB1
ACVEARARRAAAYNL	NRG2	551	O14511
ITYCELNARFGLRAI	NRXN2	901	Q9P2S2
RYASGASCLATRLNL	KLHL41	586	O60662
TLCSQELRLASYLAR	EVC2	1116	Q86UK5
YLRCITFLASFETLN	KNTC1	1916	P50748
ALLCYEATASRFRAV	LYPD4	26	Q6UWN0
VQLLRRAAAQLTYCS	ALOX12	426	P18054
LRAYLFSCRAAVAED	PLEKHM3	611	Q6ZWE6
NACALLETIRRALYI	GPR35	246	Q9HC97
VLLCCAYSAELRTRA	GPR78	26	Q96P69
YARQVDCALSLIRLG	NBAS	856	A2RRP1
TSRALTAEVYFLQCR	DZIP3	856	Q86Y13
AVLSALLTRIQRYCN	PACS1	601	Q6VY07
AVSFLVAAICYFRRL	OTULINL	51	Q9NUU6
STRYTLDFDRAQRAC	ACAN	161	P16112
SCFLINTADRIIRVY	RBBP5	211	Q15291
ARYLSDLFTTCVDVR	KCNJ14	71	Q9UNX9
NSIARLYECVLEFAR	MED14	771	O60244
SRSYQRLADACRGLL	SBF1	241	O95248
LAAVSRAEQDLYRCV	PTPRU	251	Q92729
DLQVRSAAAVICAYL	PPP4R3C	376	Q6ZMV5
LRRLFECLYVSVFSN	SRD5A3	141	Q9H8P0
RALSELAALCYLIAF	RGPD3	311	A6NKT7
RSVGAVAYLECSARL	RHOD	161	O00212
CLVAAALRYLQIFAT	FAM189A2	101	Q15884
FDCLSYSALQVLSRR	EVA1C	211	P58658
LFRGQSYEAIRAACL	CAPN12	26	Q6ZSI9
YANLCQLRAASRRSE	HTRA1	126	Q92743
SVALISLDRYCAIVR	GPR135	201	Q8IZ08
CNSDGALLRFYVRVL	CABIN1	906	Q9Y6J0
FIVQSRILYSRATCG	DOCK3	736	Q8IZD9
RYSISRTEAADLCKA	CD44	41	P16070
LVFSYLELSELRSCA	FBXO45	46	P0C2W1
RSLEQLSLVCRGFYI	FBXO9	211	Q9UK97
FVRLRVPAAYAASLC	FCGBP	4596	Q9Y6R7
VAYRRCLQILAAGLF	ILF2	266	Q12905
IANLGDSRAILCRYN	ILKAP	231	Q9H0C8
LSIFCAQAGARRVYA	PRMT6	96	Q96LA8
CSLLAIAVDRYVTIF	MC5R	131	P33032
SIERLNLYAASLRVC	GBF1	466	Q92538
NLYAASLRVCFLLFE	GBF1	471	Q92538
RSLGIAVYRCSASTR	KLHDC7A	686	Q5VTJ3
INRFTRRASVCAEAY	PRKAR2B	106	P31323
FQTYACLSRIRAQLA	DCK	96	P27707
CSSPKAALRYAAVRT	COPG1	296	Q9Y678
FGSYVSRLRRVICAS	DCST2	516	Q5T1A1
SILNLCAISIDRYTA	DRD2	121	P14416
CFLDATTASRFYRID	DGKZ	716	Q13574
RQLCAIYRLNFLTTA	HPS1	476	Q92902
IYSFRSREVCRAVLS	S1PR4	306	O95977
CSRYRLATIANFSAL	SLC22A4	81	Q9H015
CRRYRLATIANFSAL	SLC22A5	81	O76082
AARENRYDCVVLFLS	EHMT1	946	Q9H9B1
DLRRCTYSLFAALSG	IPO4	581	Q8TEX9
ELRTYLAGQIARACA	SPOUT1	91	Q5T280
ASILNLCAISIDRYT	DRD3	116	P35462
CFTVALRAAAYGVRV	LIPE	731	Q05469
TYRVCVLAANRAGLS	LRRN4	646	Q8WUT4
YARVSVRTVLDACSA	PTPN13	141	Q12923
LSRRASCFAVALALN	PTCD2	236	Q8WV60
VDALLTLIFRSRRYC	FSCN2	171	O14926
YAVTQAELFALLCRL	NR6A1	276	Q15406
TCSFDITYDRVFRAL	SMG8	216	Q8ND04
RLALTTAEFLAYQCE	ATP6V1B2	276	P21281
RALSELAALCYLIAF	RGPD4	311	Q7Z3J3
ECRLLRNFSSVYAVV	RGL2	341	O15211
RSRAFFCALLNILSI	SLC35G3	101	Q8N808
RALQLSDRGLYSCTA	SEMA3F	666	Q13275
RDVAACAVRFRLYAA	SYT16	426	Q17RD7
CAFSTLGRVLRLAYS	HPS3	56	Q969F9
LYCSAFEEAALTRRI	LMBR1L	241	Q6UX01
LYRAFARCAALVATA	RIF1	711	Q5UIP0
DALCRITALVFYINT	GPR183	101	P32249
EYVAESFLNCLRRVA	PIWIL4	496	Q7Z3Z4
ERDFASVYSRLVLCK	SGSM3	601	Q96HU1
RASESISRAYALCVL	INPP5D	31	Q92835
AALLCRSHQLAAYRD	TANC1	526	Q9C0D5
FNELRVSLYLNLSRC	TANC1	1331	Q9C0D5
VFRCLERYSEAARSA	SPATA16	271	Q9BXB7
LERSRLATTAFCGSY	SLC17A7	201	Q9P2U7
SATICYTAALLKARA	ST7	366	Q9NRC1
YTFDRNVLSRLLNEC	TNFAIP8	121	O95379
CAALRSYALCTRRTA	RGMA	76	Q96B86
RITRASALLDACGFY	SOCS1	66	O15524
LSLANCYEVLSAAKR	KBTBD11	231	O94819
ADLLDYCLARRTQAA	URB1	1216	O60287
YCLARRTQAALSIAA	URB1	1221	O60287
RSSIFRLYSRLCGAE	URB1	2146	O60287
RAEQLFSSALCAARL	PDXP	81	Q96GD0
RGDLCYLLTSQIDRA	SMCR8	346	Q8TEV9
ALYLLALRANCEFVR	TCN2	106	P20062
ALLQRYRAQTCSARL	CHPF	726	Q8IZ52
RTANIRSLGYSDLFC	CNGA2	536	Q16280
LCLSLQLSSATFIRY	PLET1	16	Q6UQ28
LLVTFVARNRSACTY	PLK3	601	Q9H4B4
VEARRYVDSRCLANL	UBA6	571	A0AVT1
TFVCIYSGRLLSRAN	SETDB2	391	Q96T68
IRLCASLLVRNLYTS	WDR90	166	Q96KV7
CERARQYLEAFATAT	ZBTB7B	156	O15156
CYFSRRRSLATGLAL	SLC16A13	131	Q7RTY0
QSYEALCELAAARRA	SPTBN2	621	O15020
ALYNQESCARVLLFR	SHANK3	291	Q9BYB0
TLRLYSAVCALGNSR	RYR3	1561	Q15413
RAQSLTCTGLYREAL	SNX21	246	Q969T3
AQALSCLTGSRAYER	XYLB	156	O75191
LNNLSERARGVCSYL	TDP2	126	O95551
RTIYICQFLTRIAAG	TERF1	121	P54274
VARYRNLNCEAGSLL	TESK1	591	Q15569
RTDAALYACRILTEA	SIGLEC1	766	Q9BZZ2
LYACRILTEAGAQLS	SIGLEC1	771	Q9BZZ2
ASLSCLLNYRVDFTF	NT5DC2	471	Q9H857
STAFLTCIAVDRYLA	GPR65	101	Q8IYL9
RVARYAVCAAGILLS	VKORC1L1	16	Q8N0U8
YLLRCRAAGQSDSSV	SLC35F6	66	Q8N357
NDSRYCLSSRLRVSA	TRB	206	P0DTU4
RSRASSECEATYLLR	TRPM1	1246	Q7Z4N2
LSQFLSYLSACDRLL	UBAP1L	301	F5GYI3
YTCTARNAAGLLRAD	WFIKKN1	261	Q96NZ8
SIERSYACSVLGRLN	ZNF26	101	P17031
RCLLTSAIYALQGRS	TTC37	1161	Q6PGP7
ATLLDLRSYLFSRQC	TRAPPC10	301	P48553
QASESLLARARCYGF	TTC34	176	A8MYJ7
ISEALSRYRNRSCFV	ZYG11A	346	Q6WRX3
ILSYNRANRAVAILC	TOP1	616	P11387
GCVLSADVFARYSRL	MARS1	286	P56192
RFVCDLTQADRLALY	SNRNP48	151	Q6IEG0
YSIQRSAFDRCATLS	UBE3C	66	Q15386
FLASFAALVLVCRQR	TMEM98	16	Q9Y2Y6
AASCSAALRAVYRLK	YRDC	96	Q86U90
RAQLLYALLAALCFA	NAT8L	116	Q8N9F0
YALLAALCFAVSRSL	NAT8L	121	Q8N9F0