Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	protein-macromolecule adaptor activity	MED14 SUPT20HL1 KMT2C SUPT20HL2 YTHDF3 MAK SH3RF1	9.34e-06	1160	15	7	GO:0030674
GeneOntologyMolecularFunction	histone H3K4 monomethyltransferase activity	KMT2C KMT2B	1.47e-05	8	15	2	GO:0140945
GeneOntologyMolecularFunction	histone H3K4 trimethyltransferase activity	KMT2C KMT2B	2.36e-05	10	15	2	GO:0140999
GeneOntologyMolecularFunction	molecular adaptor activity	MED14 SUPT20HL1 KMT2C SUPT20HL2 YTHDF3 MAK SH3RF1	2.60e-05	1356	15	7	GO:0060090
GeneOntologyMolecularFunction	transcription coregulator activity	MED14 SUPT20HL1 KMT2C SUPT20HL2 MAK	4.12e-05	562	15	5	GO:0003712
GeneOntologyMolecularFunction	histone H3K4 methyltransferase activity	KMT2C KMT2B	9.93e-05	20	15	2	GO:0042800
GeneOntologyMolecularFunction	histone H3 methyltransferase activity	KMT2C KMT2B	4.89e-04	44	15	2	GO:0140938
GeneOntologyMolecularFunction	protein-lysine N-methyltransferase activity	KMT2C KMT2B	1.17e-03	68	15	2	GO:0016279
GeneOntologyMolecularFunction	lysine N-methyltransferase activity	KMT2C KMT2B	1.20e-03	69	15	2	GO:0016278
GeneOntologyMolecularFunction	histone methyltransferase activity	KMT2C KMT2B	1.27e-03	71	15	2	GO:0042054
GeneOntologyMolecularFunction	transcription coactivator activity	MED14 KMT2C MAK	1.37e-03	303	15	3	GO:0003713
GeneOntologyMolecularFunction	chromatin binding	SREBF2 CHD8 TOX4 PHC2	1.83e-03	739	15	4	GO:0003682
GeneOntologyMolecularFunction	protein methyltransferase activity	KMT2C KMT2B	2.65e-03	103	15	2	GO:0008276
GeneOntologyMolecularFunction	N-methyltransferase activity	KMT2C KMT2B	2.75e-03	105	15	2	GO:0008170
GeneOntologyMolecularFunction	S-adenosylmethionine-dependent methyltransferase activity	KMT2C KMT2B	7.20e-03	172	15	2	GO:0008757
GeneOntologyBiologicalProcess	positive regulation of transcription by RNA polymerase II	SREBF2 MED14 SUPT20HL1 CCNK KMT2C CHD8 SUPT20HL2	2.47e-05	1390	15	7	GO:0045944
GeneOntologyCellularComponent	transferase complex	SUPT20HL1 CCNK KMT2C CHD8 SUPT20HL2 PHC2 KMT2B	2.00e-06	963	15	7	GO:1990234
GeneOntologyCellularComponent	histone methyltransferase complex	KMT2C CHD8 KMT2B	1.96e-05	75	15	3	GO:0035097
GeneOntologyCellularComponent	methyltransferase complex	KMT2C CHD8 KMT2B	5.83e-05	108	15	3	GO:0034708
GeneOntologyCellularComponent	SAGA complex	SUPT20HL1 SUPT20HL2	1.43e-04	25	15	2	GO:0000124
GeneOntologyCellularComponent	nuclear protein-containing complex	MED14 CCNK KMT2C CHD8 PHC2 KMT2B	2.41e-04	1377	15	6	GO:0140513
GeneOntologyCellularComponent	MLL1/2 complex	CHD8 KMT2B	2.51e-04	33	15	2	GO:0044665
GeneOntologyCellularComponent	SAGA-type complex	SUPT20HL1 SUPT20HL2	3.51e-04	39	15	2	GO:0070461
GeneOntologyCellularComponent	chromatin	SREBF2 SUPT20HL1 CHD8 SUPT20HL2 TOX4 PHC2	3.57e-04	1480	15	6	GO:0000785
GeneOntologyCellularComponent	histone acetyltransferase complex	SUPT20HL1 SUPT20HL2	2.02e-03	94	15	2	GO:0000123
GeneOntologyCellularComponent	protein acetyltransferase complex	SUPT20HL1 SUPT20HL2	2.47e-03	104	15	2	GO:0031248
GeneOntologyCellularComponent	acetyltransferase complex	SUPT20HL1 SUPT20HL2	2.71e-03	109	15	2	GO:1902493
GeneOntologyCellularComponent	peptidase complex	SUPT20HL1 SUPT20HL2	4.00e-03	133	15	2	GO:1905368
HumanPheno	Typically de novo	KMT2C CHD8	5.07e-05	12	5	2	HP:0025352
MousePheno	abnormal left-right axis symmetry of the somites	SUPT20HL1 SUPT20HL2	3.00e-05	8	15	2	MP:0005224
MousePheno	abnormal gastrulation movements	SUPT20HL1 SUPT20HL2	4.81e-05	10	15	2	MP:0002174
MousePheno	abnormal mesoderm morphology	SUPT20HL1 CHD8 SUPT20HL2	3.08e-04	127	15	3	MP:0014141
MousePheno	abnormal rostral-caudal axis patterning	SUPT20HL1 SUPT20HL2 KMT2B	3.45e-04	132	15	3	MP:0005221
MousePheno	abnormal germ layer development	SUPT20HL1 CHD8 SUPT20HL2	4.45e-04	144	15	3	MP:0001674
MousePheno	abnormal germ layer morphology	SUPT20HL1 CHD8 SUPT20HL2	6.16e-04	161	15	3	MP:0014138
MousePheno	abnormal paraxial mesoderm morphology	SUPT20HL1 SUPT20HL2	8.19e-04	40	15	2	MP:0008029
MousePheno	embryo tissue necrosis	SUPT20HL1 SUPT20HL2	8.19e-04	40	15	2	MP:0013241
MousePheno	prenatal lethality, incomplete penetrance	SREBF2 SUPT20HL1 KMT2C SUPT20HL2 KMT2B	8.24e-04	747	15	5	MP:0011101
MousePheno	incomplete somite formation	SUPT20HL1 SUPT20HL2	9.91e-04	44	15	2	MP:0001689
MousePheno	abnormal primitive streak morphology	SUPT20HL1 CHD8 SUPT20HL2	1.17e-03	201	15	3	MP:0002231
MousePheno	abnormal gastrulation	SUPT20HL1 CHD8 SUPT20HL2 KMT2B	1.27e-03	469	15	4	MP:0001695
MousePheno	caudal body truncation	SUPT20HL1 SUPT20HL2	1.49e-03	54	15	2	MP:0004073
MousePheno	abnormal somite development	SUPT20HL1 SUPT20HL2 KMT2B	1.56e-03	222	15	3	MP:0001688
MousePheno	failure of initiation of embryo turning	SUPT20HL1 SUPT20HL2	1.60e-03	56	15	2	MP:0004180
MousePheno	open neural tube	SUPT20HL1 SUPT20HL2 KMT2B	1.64e-03	226	15	3	MP:0000929
MousePheno	exencephaly	SUPT20HL1 SUPT20HL2 KMT2B	1.73e-03	230	15	3	MP:0000914
MousePheno	abnormal head fold morphology	SUPT20HL1 SUPT20HL2	2.08e-03	64	15	2	MP:0011257
MousePheno	abnormal embryo turning	SUPT20HL1 SUPT20HL2 KMT2B	2.22e-03	251	15	3	MP:0001700
MousePheno	abnormal left-right axis patterning	SUPT20HL1 SUPT20HL2	2.28e-03	67	15	2	MP:0001706
MousePheno	failure of chorioallantoic fusion	SUPT20HL1 SUPT20HL2	2.28e-03	67	15	2	MP:0009657
MousePheno	abnormal developmental patterning	SUPT20HL1 CHD8 SUPT20HL2 KMT2B	2.73e-03	577	15	4	MP:0002084
MousePheno	abnormal mesoderm development	SUPT20HL1 SUPT20HL2	2.78e-03	74	15	2	MP:0001680
Domain	FYrich_C	KMT2C KMT2B	5.21e-06	5	14	2	IPR003889
Domain	FYrich_N	KMT2C KMT2B	5.21e-06	5	14	2	IPR003888
Domain	FYRC	KMT2C KMT2B	5.21e-06	5	14	2	SM00542
Domain	FYRN	KMT2C KMT2B	5.21e-06	5	14	2	SM00541
Domain	FYRN	KMT2C KMT2B	5.21e-06	5	14	2	PF05964
Domain	FYRC	KMT2C KMT2B	5.21e-06	5	14	2	PF05965
Domain	FYRC	KMT2C KMT2B	5.21e-06	5	14	2	PS51543
Domain	FYRN	KMT2C KMT2B	5.21e-06	5	14	2	PS51542
Domain	PostSET	KMT2C KMT2B	6.22e-05	16	14	2	SM00508
Domain	Post-SET_dom	KMT2C KMT2B	6.22e-05	16	14	2	IPR003616
Domain	POST_SET	KMT2C KMT2B	6.22e-05	16	14	2	PS50868
Domain	EPHD	KMT2C KMT2B	1.20e-04	22	14	2	PS51805
Domain	AT_hook	KMT2C KMT2B	1.81e-04	27	14	2	SM00384
Domain	AT_hook_DNA-bd_motif	KMT2C KMT2B	1.81e-04	27	14	2	IPR017956
Domain	SET	KMT2C KMT2B	4.21e-04	41	14	2	PF00856
Domain	SET	KMT2C KMT2B	5.30e-04	46	14	2	SM00317
Domain	SET_dom	KMT2C KMT2B	6.26e-04	50	14	2	IPR001214
Domain	SET	KMT2C KMT2B	6.26e-04	50	14	2	PS50280
Domain	HMG_box	KMT2C TOX4	7.03e-04	53	14	2	PF00505
Domain	HMG	KMT2C TOX4	7.30e-04	54	14	2	SM00398
Domain	HMG_box_dom	KMT2C TOX4	1.06e-03	65	14	2	IPR009071
Domain	PHD	KMT2C KMT2B	1.40e-03	75	14	2	PF00628
Domain	Znf_PHD-finger	KMT2C KMT2B	1.56e-03	79	14	2	IPR019787
Domain	PHD	KMT2C KMT2B	1.97e-03	89	14	2	SM00249
Domain	Znf_PHD	KMT2C KMT2B	2.06e-03	91	14	2	IPR001965
Domain	ZF_PHD_2	KMT2C KMT2B	2.24e-03	95	14	2	PS50016
Domain	ZF_PHD_1	KMT2C KMT2B	2.29e-03	96	14	2	PS01359
Domain	-	KMT2C KMT2B SH3RF1	4.12e-03	449	14	3	3.30.40.10
Domain	Znf_RING/FYVE/PHD	KMT2C KMT2B SH3RF1	4.39e-03	459	14	3	IPR013083
Domain	Znf_FYVE_PHD	KMT2C KMT2B	5.26e-03	147	14	2	IPR011011
Domain	ZF_RING_2	KMT2C SH3RF1	2.03e-02	298	14	2	PS50089
Domain	RING	KMT2C SH3RF1	2.13e-02	305	14	2	SM00184
Domain	Znf_RING	KMT2C SH3RF1	2.41e-02	326	14	2	IPR001841
Pubmed	A human MAP kinase interactome.	SREBF2 CSN2 KMT2C CHD8 TOX4 SH3RF1	5.13e-08	486	16	6	20936779
Pubmed	SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.	CCNK KMT2C CHD8 TOX4 KMT2B	7.70e-08	251	16	5	31076518
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	MED14 CCNK KMT2C CHD8 TOX4 KMT2B	1.05e-07	549	16	6	38280479
Pubmed	Quantitative dissection and stoichiometry determination of the human SET1/MLL histone methyltransferase complexes.	MED14 KMT2C TOX4 KMT2B	2.30e-07	119	16	4	23508102
Pubmed	Identification and characterization of a novel human PP1 phosphatase complex.	KMT2C TOX4 KMT2B	3.56e-07	31	16	3	20516061
Pubmed	The p38-interacting protein (p38IP) regulates G2/M progression by promoting α-tubulin acetylation via inhibiting ubiquitination-induced degradation of the acetyltransferase GCN5.	SUPT20HL1 SUPT20HL2	5.95e-07	3	16	2	24220028
Pubmed	Impact of WIN site inhibitor on the WDR5 interactome.	KMT2C CHD8 KMT2B	9.75e-07	43	16	3	33472061
Pubmed	Crucial roles for interactions between MLL3/4 and INI1 in nuclear receptor transactivation.	KMT2C KMT2B	1.19e-06	4	16	2	19221051
Pubmed	A subset of mixed lineage leukemia proteins has plant homeodomain (PHD)-mediated E3 ligase activity.	KMT2C KMT2B	1.19e-06	4	16	2	23129768
Pubmed	Human GW182 Paralogs Are the Central Organizers for RNA-Mediated Control of Transcription.	MED14 KMT2C KMT2B	2.56e-06	59	16	3	28813667
Pubmed	Coactivator as a target gene specificity determinant for histone H3 lysine 4 methyltransferases.	KMT2C KMT2B	2.97e-06	6	16	2	17021013
Pubmed	ASCOM controls farnesoid X receptor transactivation through its associated histone H3 lysine 4 methyltransferase activity.	KMT2C KMT2B	4.16e-06	7	16	2	19556342
Pubmed	A tumor suppressive coactivator complex of p53 containing ASC-2 and histone H3-lysine-4 methyltransferase MLL3 or its paralogue MLL4.	KMT2C KMT2B	4.16e-06	7	16	2	19433796
Pubmed	Structural insights into trans-histone regulation of H3K4 methylation by unique histone H4 binding of MLL3/4.	KMT2C KMT2B	4.16e-06	7	16	2	30604749
Pubmed	Skirting the pitfalls: a clear-cut nomenclature for H3K4 methyltransferases.	KMT2C KMT2B	5.55e-06	8	16	2	23130995
Pubmed	Crosstalk between Nodal/activin and MAPK p38 signaling is essential for anterior-posterior axis specification.	SUPT20HL1 SUPT20HL2	5.55e-06	8	16	2	21802298
Pubmed	The plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferases.	KMT2C KMT2B	5.55e-06	8	16	2	22266653
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	MED14 KMT2C CHD8 PHC2 KMT2B SH3RF1	6.18e-06	1105	16	6	35748872
Pubmed	The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition.	MED14 CCNK YTHDF3 PHC2	7.03e-06	281	16	4	24163370
Pubmed	Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases.	KMT2C KMT2B	7.13e-06	9	16	2	22665483
Pubmed	Glucagon regulates gluconeogenesis through KAT2B- and WDR5-mediated epigenetic effects.	SUPT20HL1 SUPT20HL2	1.09e-05	11	16	2	24051374
Pubmed	Targeted Disruption of the Interaction between WD-40 Repeat Protein 5 (WDR5) and Mixed Lineage Leukemia (MLL)/SET1 Family Proteins Specifically Inhibits MLL1 and SETd1A Methyltransferase Complexes.	KMT2C KMT2B	1.31e-05	12	16	2	27563068
Pubmed	MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.	CCNK CHD8 TOX4 KMT2B	1.47e-05	339	16	4	30415952
Pubmed	Dynamic patterns of histone H3 lysine 4 methyltransferases and demethylases during mouse preimplantation development.	KMT2C KMT2B	1.54e-05	13	16	2	24619213
Pubmed	Histone demethylase JMJD2B coordinates H3K4/H3K9 methylation and promotes hormonally responsive breast carcinogenesis.	KMT2C KMT2B	1.54e-05	13	16	2	21502505
Pubmed	Interaction network of human early embryonic transcription factors.	KMT2C CHD8 YTHDF3 KMT2B	1.69e-05	351	16	4	38297188
Pubmed	A set of proteins interacting with transcription factor Sp1 identified in a two-hybrid screening.	SREBF2 PHC2	1.80e-05	14	16	2	10976766
Pubmed	SET1 and p300 act synergistically, through coupled histone modifications, in transcriptional activation by p53.	KMT2C KMT2B	2.37e-05	16	16	2	23870121
Pubmed	H3K4 mono- and di-methyltransferase MLL4 is required for enhancer activation during cell differentiation.	KMT2C KMT2B	2.37e-05	16	16	2	24368734
Pubmed	MLL3 and MLL4 Methyltransferases Bind to the MAFA and MAFB Transcription Factors to Regulate Islet β-Cell Function.	KMT2C KMT2B	2.69e-05	17	16	2	26180087
Pubmed	BioID identifies novel c-MYC interacting partners in cultured cells and xenograft tumors.	CCNK CHD8 KMT2B	3.02e-05	134	16	3	25452129
Pubmed	PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex.	KMT2C KMT2B	3.02e-05	18	16	2	17500065
Pubmed	An ARC/Mediator subunit required for SREBP control of cholesterol and lipid homeostasis.	SREBF2 MED14	3.38e-05	19	16	2	16799563
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	MED14 CCNK KMT2C CHD8 PHC2 KMT2B	3.47e-05	1497	16	6	31527615
Pubmed	Targeted inactivation of MLL3 histone H3-Lys-4 methyltransferase activity in the mouse reveals vital roles for MLL3 in adipogenesis.	KMT2C KMT2B	3.75e-05	20	16	2	19047629
Pubmed	Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition.	KMT2C KMT2B	4.15e-05	21	16	2	27626377
Pubmed	Cripto is required for mesoderm and endoderm cell allocation during mouse gastrulation.	SUPT20HL1 SUPT20HL2	4.15e-05	21	16	2	23747598
Pubmed	Supt20 is required for development of the axial skeleton.	SUPT20HL1 SUPT20HL2	4.15e-05	21	16	2	27894818
Pubmed	Structural basis for activity regulation of MLL family methyltransferases.	KMT2C KMT2B	4.56e-05	22	16	2	26886794
Pubmed	p38 and a p38-interacting protein are critical for downregulation of E-cadherin during mouse gastrulation.	SUPT20HL1 SUPT20HL2	4.56e-05	22	16	2	16751104
Pubmed	The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.	CHD8 PHC2 KMT2B	4.84e-05	157	16	3	30186101
Pubmed	Genomic analysis of mouse retinal development.	SREBF2 CCNK MAK PHC2 KMT2B	6.71e-05	1006	16	5	15226823
Pubmed	Rebalancing gene haploinsufficiency in vivo by targeting chromatin.	KMT2C KMT2B	7.45e-05	28	16	2	27256596
Pubmed	The human SPT20-containing SAGA complex plays a direct role in the regulation of endoplasmic reticulum stress-induced genes.	SUPT20HL1 SUPT20HL2	7.45e-05	28	16	2	19114550
Pubmed	A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing.	SUPT20HL1 SUPT20HL2	8.57e-05	30	16	2	18206972
Pubmed	The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.	CHD8 YTHDF3 TOX4	9.49e-05	197	16	3	20811636
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	MED14 CCNK KMT2C CHD8 KMT2B	1.04e-04	1103	16	5	34189442
Pubmed	Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage-binding factors in vivo.	SUPT20HL1 SUPT20HL2	1.04e-04	33	16	2	11564863
Pubmed	A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.	CCNK TOX4 PHC2 KMT2B	1.42e-04	608	16	4	16713569
Pubmed	Single-cell profiling of epigenetic modifiers identifies PRDM14 as an inducer of cell fate in the mammalian embryo.	KMT2C KMT2B	1.86e-04	44	16	2	24183668
Pubmed	Quantitative Proteomics of the SMAD (Suppressor of Mothers against Decapentaplegic) Transcription Factor Family Identifies Importin 5 as a Bone Morphogenic Protein Receptor SMAD-specific Importin.	MED14 KMT2C	2.21e-04	48	16	2	27703004
Pubmed	Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice.	KMT2C KMT2B	2.30e-04	49	16	2	34368113
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	MED14 CCNK CHD8	2.35e-04	268	16	3	33640491
Pubmed	Epigenetic-focused CRISPR/Cas9 screen identifies (absent, small, or homeotic)2-like protein (ASH2L) as a regulator of glioblastoma cell survival.	KMT2C KMT2B	2.40e-04	50	16	2	37974198
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	SREBF2 KMT2C TOX4 SH3RF1	2.56e-04	709	16	4	22988430
Pubmed	Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.	CCNK CHD8 TOX4	2.76e-04	283	16	3	30585729
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	ARHGAP5 CCNK YTHDF3 TOX4 PHC2	2.87e-04	1371	16	5	36244648
Pubmed	New nomenclature for chromatin-modifying enzymes.	KMT2C KMT2B	3.12e-04	57	16	2	18022353
Pubmed	A lentiviral functional proteomics approach identifies chromatin remodeling complexes important for the induction of pluripotency.	KMT2C KMT2B	3.57e-04	61	16	2	20305087
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	MED14 CCNK PHC2 KMT2B	3.58e-04	774	16	4	15302935
Pubmed	PRC1 and PRC2 are not required for targeting of H2A.Z to developmental genes in embryonic stem cells.	MED14 PHC2	4.06e-04	65	16	2	22496869
Pubmed	Genetic interaction mapping in mammalian cells using CRISPR interference.	MED14 PHC2	4.57e-04	69	16	2	28481362
Interaction	MEN1 interactions	MED14 ARHGAP5 CCNK KMT2C CHD8 YTHDF3 TOX4 KMT2B	2.10e-07	1029	15	8	int:MEN1
Interaction	SETD1A interactions	CCNK KMT2C CHD8 KMT2B	6.20e-06	170	15	4	int:SETD1A
Interaction	PHF20 interactions	KMT2C CHD8 KMT2B	7.64e-06	53	15	3	int:PHF20
Interaction	ASH2L interactions	MED14 KMT2C CHD8 KMT2B	3.56e-05	265	15	4	int:ASH2L
Interaction	HNF4A interactions	SREBF2 MED14 KMT2C KMT2B	4.11e-05	275	15	4	int:HNF4A
Interaction	TOP3B interactions	MED14 KMT2C CHD8 YTHDF3 PHC2 KMT2B SH3RF1	4.13e-05	1470	15	7	int:TOP3B
Interaction	TNRC6A interactions	MED14 KMT2C YTHDF3 KMT2B	4.41e-05	280	15	4	int:TNRC6A
Interaction	KMT2A interactions	MED14 KMT2C CHD8 KMT2B	6.89e-05	314	15	4	int:KMT2A
Interaction	HECW2 interactions	MED14 CCNK YTHDF3 PHC2	7.60e-05	322	15	4	int:HECW2
Interaction	ZYX interactions	SREBF2 ARHGAP5 YTHDF3 SH3RF1	8.26e-05	329	15	4	int:ZYX
Interaction	YAP1 interactions	MED14 CCNK KMT2C CHD8 TOX4 KMT2B	8.31e-05	1095	15	6	int:YAP1
Interaction	GFI1B interactions	MED14 CHD8 PHC2	1.29e-04	136	15	3	int:GFI1B
Interaction	MEX3A interactions	SREBF2 CHD8 YTHDF3 TOX4	1.50e-04	384	15	4	int:MEX3A
Interaction	UNK interactions	MED14 ARHGAP5 YTHDF3 SH3RF1	1.89e-04	408	15	4	int:UNK
Interaction	SMAD3 interactions	SREBF2 CHD8 PHC2 KMT2B	2.68e-04	447	15	4	int:SMAD3
Interaction	ATN1 interactions	KMT2C KMT2B SH3RF1	3.29e-04	187	15	3	int:ATN1
Interaction	WDR82 interactions	KMT2C TOX4 KMT2B	4.82e-04	213	15	3	int:WDR82
Cytoband	Xp22.11	SUPT20HL1 SUPT20HL2	2.38e-05	21	16	2	Xp22.11
Cytoband	14q11.2	CHD8 TOX4	1.77e-03	180	16	2	14q11.2
Cytoband	Ensembl 112 genes in cytogenetic band chrXp22	SUPT20HL1 SUPT20HL2	3.37e-03	250	16	2	chrXp22
Cytoband	Ensembl 112 genes in cytogenetic band chr14q11	CHD8 TOX4	5.85e-03	332	16	2	chr14q11
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	KMT2C KMT2B	9.54e-05	34	8	2	487
GeneFamily	PHD finger proteins	KMT2C KMT2B	6.73e-04	90	8	2	88
Coexpression	DAZARD_RESPONSE_TO_UV_SCC_DN	CHD8 YTHDF3 PHC2	4.42e-05	115	16	3	M7484
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#4_top-relative-expression-ranked_1000	ARHGAP5 KMT2C CHD8	7.25e-05	127	14	3	gudmap_developingGonad_e16.5_epididymis_1000_k4
Disease	congenital heart disease (implicated_via_orthology)	KMT2C CHD8 KMT2B	6.71e-06	69	16	3	DOID:1682 (implicated_via_orthology)
Disease	prostate cancer (is_marker_for)	SREBF2 KMT2C KMT2B	7.72e-05	156	16	3	DOID:10283 (is_marker_for)
Disease	Liver carcinoma	SREBF2 KMT2C KMT2B	2.39e-03	507	16	3	C2239176
Disease	body weight	CHD8 TOX4 PHC2 SH3RF1	4.00e-03	1261	16	4	EFO_0004338
Disease	Hereditary Diffuse Gastric Cancer	SREBF2 KMT2C	1.08e-02	293	16	2	C1708349
Disease	Stomach Neoplasms	SREBF2 KMT2C	1.10e-02	297	16	2	C0038356
Disease	Malignant neoplasm of stomach	SREBF2 KMT2C	1.13e-02	300	16	2	C0024623

Protein segments in the cluster

Peptide	Gene	Start	Entry
IQIVPQPPSSQPQPQ	CHD8	351	Q9HCK8
PPSLQPTPQVPQVQQ	CCNK	276	O75909
LNPPRIQPPIAQLPI	KMT2C	3346	Q8NEZ4
VQQQQVLQGPPLPRP	EP400P1	266	Q6ZTU2
TQLLPQALPPPQPQL	KMT2B	746	Q9UMN6
LISQLQPPPQQQPFP	MED14	996	O60244
QQVPQPIPQTLALPP	CSN2	151	P05814
VPQPKVLPIPQQVVP	CSN2	171	P05814
QPKTSQQPLQPIQPP	MAK	336	P20794
PIQPPQNLSVQQPPK	MAK	346	P20794
LPSVLRQQQPQPQPP	SUPT20HL1	716	Q3ZLR7
QPQPPKLQLQPQWQP	SUPT20HL1	726	Q3ZLR7
LPPPLQPQLIQPQLQ	ARHGAP5	1481	Q13017
NFVQIIKPLPQPPPQ	SH3RF1	186	Q7Z6J0
QPQPLLLLQPQPQPQ	SUPT20HL2	751	P0C7V6
PPQTIIQQPQPLIQP	YTHDF3	296	Q7Z739
IQQPQPLIQPPPLVQ	YTHDF3	301	Q7Z739
PLIQPPPLVQSQLPQ	YTHDF3	306	Q7Z739
PPLVQSQLPQQQPQP	YTHDF3	311	Q7Z739
PQQQQPPPQQSRPVL	PHC2	356	Q8IXK0
LQPRPQPQPQPQTQL	SREBF2	131	Q12772
PPLQQMPQPPTQQQV	TOX4	446	O94842
PPQKVRINLQQQPPP	TOX4	476	O94842