Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	cellular response to interleukin-17	IL17A DCP1B IL17RA	5.77e-05	24	65	3	GO:0097398
GeneOntologyBiologicalProcess	response to interleukin-17	IL17A DCP1B IL17RA	8.28e-05	27	65	3	GO:0097396
GeneOntologyBiologicalProcess	positive regulation of chemokine (C-X-C motif) ligand 1 production	IL17A IL17RA	9.72e-05	5	65	2	GO:2000340
GeneOntologyBiologicalProcess	chemokine (C-X-C motif) ligand 1 production	IL17A IL17RA	1.45e-04	6	65	2	GO:0072566
GeneOntologyBiologicalProcess	interleukin-17A-mediated signaling pathway	IL17A IL17RA	1.45e-04	6	65	2	GO:0038173
GeneOntologyBiologicalProcess	regulation of chemokine (C-X-C motif) ligand 1 production	IL17A IL17RA	1.45e-04	6	65	2	GO:2000338
GeneOntologyBiologicalProcess	positive regulation of interleukin-23 production	IL17A IL17RA	2.03e-04	7	65	2	GO:0032747
GeneOntologyCellularComponent	P-body	DCP1B SAMD4B TRIM21 PATL1	2.71e-04	102	64	4	GO:0000932
Domain	ConA-like_dom	COL15A1 NBEAL1 NBEAL2 LAMA1 TRIM21 HERC1 RYR2	9.76e-06	219	64	7	IPR013320
Domain	DUF4704	NBEAL1 NBEAL2	1.15e-04	5	64	2	IPR031570
Domain	DUF4704	NBEAL1 NBEAL2	1.15e-04	5	64	2	PF15787
Domain	PH_BEACH	NBEAL1 NBEAL2	1.72e-04	6	64	2	PF14844
Domain	PH-BEACH_dom	NBEAL1 NBEAL2	3.19e-04	8	64	2	IPR023362
Domain	-	NBEAL1 NBEAL2	3.19e-04	8	64	2	2.30.29.40
Domain	PH_BEACH	NBEAL1 NBEAL2	3.19e-04	8	64	2	PS51783
Domain	BEACH_dom	NBEAL1 NBEAL2	4.10e-04	9	64	2	IPR000409
Domain	BEACH	NBEAL1 NBEAL2	4.10e-04	9	64	2	PS50197
Domain	Beach	NBEAL1 NBEAL2	4.10e-04	9	64	2	PF02138
Domain	-	NBEAL1 NBEAL2	4.10e-04	9	64	2	1.10.1540.10
Domain	Beach	NBEAL1 NBEAL2	4.10e-04	9	64	2	SM01026
Domain	Fd_Rdtase_FAD-bd	DUOX1 CYB5R2	1.90e-03	19	64	2	IPR017927
Domain	FAD_FR	DUOX1 CYB5R2	1.90e-03	19	64	2	PS51384
Domain	Riboflavin_synthase-like_b-brl	DUOX1 CYB5R2	1.90e-03	19	64	2	IPR017938
Domain	SPRY	TRIM21 HERC1 RYR2	3.31e-03	87	64	3	SM00449
Domain	HECT	UBE3B HERC1	3.84e-03	27	64	2	PF00632
Domain	HECTc	UBE3B HERC1	3.84e-03	27	64	2	SM00119
Domain	HECT_dom	UBE3B HERC1	3.84e-03	27	64	2	IPR000569
Domain	HECT	UBE3B HERC1	3.84e-03	27	64	2	PS50237
Domain	SPRY	TRIM21 HERC1 RYR2	4.12e-03	94	64	3	PF00622
Domain	SPRY_dom	TRIM21 HERC1 RYR2	4.12e-03	94	64	3	IPR003877
Domain	B30.2/SPRY	TRIM21 HERC1 RYR2	4.24e-03	95	64	3	IPR001870
Domain	B302_SPRY	TRIM21 HERC1 RYR2	4.24e-03	95	64	3	PS50188
Domain	ARM-type_fold	CAND1 NBEAL1 DOCK8 NBEAL2 ZYG11B	6.08e-03	339	64	5	IPR016024
Pubmed	Critical role of IL-17RA in immunopathology of influenza infection.	IL17A IL17RA TNFRSF1B	2.73e-08	4	67	3	19783685
Pubmed	IL-1 and IL-23 mediate early IL-17A production in pulmonary inflammation leading to late fibrosis.	IL17A IL17RA IL1R1	6.81e-08	5	67	3	21858022
Pubmed	Oral epithelial cells orchestrate innate type 17 responses to Candida albicans through the virulence factor candidalysin.	IL17A IL17RA IL1R1	1.36e-07	6	67	3	29101209
Pubmed	IL-17A Is Increased in Humans with Primary Hyperparathyroidism and Mediates PTH-Induced Bone Loss in Mice.	IL17A IL17RA TNFRSF1B	1.36e-07	6	67	3	26456334
Pubmed	Microbiota regulate innate immune signaling and protective immunity against cancer.	IL17A IL17RA IL1R1	3.80e-07	8	67	3	33894128
Pubmed	IL-17 is essential for host defense against cutaneous Staphylococcus aureus infection in mice.	IL17A IL17RA IL1R1	3.80e-07	8	67	3	20364087
Pubmed	Immunity to the microbiota promotes sensory neuron regeneration.	IL17A IL17RA IL1R1	1.48e-06	12	67	3	36640762
Pubmed	Interleukin-17A regulates ependymal cell proliferation and functional recovery after spinal cord injury in mice.	IL17A IL17RA	3.66e-06	2	67	2	34344859
Pubmed	Interleukin-17A Facilitates Chikungunya Virus Infection by Inhibiting IFN-α2 Expression.	IL17A IL17RA	3.66e-06	2	67	2	33304351
Pubmed	Expression and function of pro-inflammatory interleukin IL-17 and IL-17 receptor in normal, benign hyperplastic, and malignant prostate.	IL17A IL17RA	3.66e-06	2	67	2	12772186
Pubmed	Escherichia coli heat-labile enterotoxin promotes protective Th17 responses against infection by driving innate IL-1 and IL-23 production.	IL17A IL1R1	3.66e-06	2	67	2	21490151
Pubmed	Mechanistic Insights into the Roles of the IL-17/IL-17R Families in Pancreatic Cancer.	IL17A IL17RA	3.66e-06	2	67	2	37686343
Pubmed	Molecular characterization of the human interleukin (IL)-17 receptor.	IL17A IL17RA	3.66e-06	2	67	2	9367539
Pubmed	Role of IL-17A in murine models of COPD airway disease.	IL17A IL17RA	3.66e-06	2	67	2	27913421
Pubmed	Proinflammatory T helper type 17 cells are effective B-cell helpers.	IL17A IL17RA	3.66e-06	2	67	2	20660725
Pubmed	Gene polymorphisms of interleukin-17 and interleukin-17 receptor are associated with end-stage kidney disease.	IL17A IL17RA	3.66e-06	2	67	2	23147652
Pubmed	Role of Interleukin 17A in Aortic Valve Inflammation in Apolipoprotein E-deficient Mice.	IL17A IL17RA	3.66e-06	2	67	2	32862384
Pubmed	Interleukin-7 and soluble Interleukin-7 receptor levels in type 1 diabetes - Impact of IL7RA polymorphisms, HLA risk genotypes and clinical features.	IL17A IL17RA	3.66e-06	2	67	2	35063672
Pubmed	Th17-polarized immune response in a murine model of hypersensitivity pneumonitis and lung fibrosis.	IL17A IL17RA	3.66e-06	2	67	2	19109199
Pubmed	Association between interleukin 17/interleukin 17 receptor gene polymorphisms and papillary thyroid cancer in Korean population.	IL17A IL17RA	3.66e-06	2	67	2	25484349
Pubmed	Effects of interleukin-17A in nucleus pulposus cells and its small-molecule inhibitors for intervertebral disc disease.	IL17A IL17RA	3.66e-06	2	67	2	30207057
Pubmed	Interleukin-17 receptor expression on vascular endothelial cells of masses of skeletal extramedullary disease in myeloma patients.	IL17A IL17RA	3.66e-06	2	67	2	24916639
Pubmed	An alternative pathway of imiquimod-induced psoriasis-like skin inflammation in the absence of interleukin-17 receptor a signaling.	IL17A IL17RA	3.66e-06	2	67	2	22951726
Pubmed	Lentivirus mediated IL-17R blockade improves diastolic cardiac function in spontaneously hypertensive rats.	IL17A IL17RA	3.66e-06	2	67	2	21530504
Pubmed	A bone-protective role for IL-17 receptor signaling in ovariectomy-induced bone loss.	IL17A IL17RA	3.66e-06	2	67	2	19731364
Pubmed	Ex vivo IL-1 receptor type I expression in human CD4+ T cells identifies an early intermediate in the differentiation of Th17 from FOXP3+ naive regulatory T cells.	IL17A IL1R1	3.66e-06	2	67	2	21998454
Pubmed	Serum IL-17A concentration and a IL17RA single nucleotide polymorphism contribute to the risk of autoimmune type 1 diabetes.	IL17A IL17RA	3.66e-06	2	67	2	35583128
Pubmed	Genetic association between interleukin-17 and susceptibility to rheumatoid arthritis.	IL17A IL17RA	3.66e-06	2	67	2	37926850
Pubmed	Loss of Sprouty4 in T cells ameliorates experimental autoimmune encephalomyelitis in mice by negatively regulating IL-1β receptor expression.	SPRY4 IL1R1	3.66e-06	2	67	2	24732356
Pubmed	IL-17A/IL-17RA interaction promoted metastasis of osteosarcoma cells.	IL17A IL17RA	3.66e-06	2	67	2	23192273
Pubmed	Influenza A exacerbates Staphylococcus aureus pneumonia by attenuating IL-1β production in mice.	IL17RA IL1R1	3.66e-06	2	67	2	24089191
Pubmed	[Expression and significance of interleukin-17 and its receptor in nasal polyps].	IL17A IL17RA	3.66e-06	2	67	2	16874957
Pubmed	IL-17A/F-signaling does not contribute to the initial phase of mucosal inflammation triggered by S. Typhimurium.	IL17A IL17RA	3.66e-06	2	67	2	21124903
Pubmed	Functional interleukin-17 receptor A are present in the thyroid gland in intractable Graves disease.	IL17A IL17RA	3.66e-06	2	67	2	23501056
Pubmed	IL-17A plays a critical role in the pathogenesis of liver fibrosis through hepatic stellate cell activation.	IL17A IL17RA	3.66e-06	2	67	2	23842754
Pubmed	Cardiac fibroblasts mediate IL-17A-driven inflammatory dilated cardiomyopathy.	IL17A IL17RA	3.66e-06	2	67	2	24935258
Pubmed	IL-17A is involved in diabetic inflammatory pathogenesis by its receptor IL-17RA.	IL17A IL17RA	3.66e-06	2	67	2	32903039
Pubmed	The effect of interleukin-17 on the proliferation and invasion of JEG-3 human choriocarcinoma cells.	IL17A IL17RA	3.66e-06	2	67	2	16533341
Pubmed	IL-17A increases ADP-induced platelet aggregation.	IL17A IL17RA	3.66e-06	2	67	2	21530487
Pubmed	The interleukin 17 system in cortical lesions in focal cortical dysplasias.	IL17A IL17RA	3.66e-06	2	67	2	23334598
Pubmed	Polymorphisms at the IL17A and IL17RA Genes are Associated with Prognosis of Papillary Thyroid Carcinoma.	IL17A IL17RA	3.66e-06	2	67	2	34384609
Pubmed	IL17A and IL17RA gene polymorphisms in Fanconi anemia.	IL17A IL17RA	3.66e-06	2	67	2	36790253
Pubmed	IL-17 potentiates neuronal injury induced by oxygen-glucose deprivation and affects neuronal IL-17 receptor expression.	IL17A IL17RA	3.66e-06	2	67	2	19457561
Pubmed	IL-17A produced by γδ T cells promotes tumor growth in hepatocellular carcinoma.	IL17A IL1R1	3.66e-06	2	67	2	24525743
Pubmed	Compressive force stimulates the gene expression of IL-17s and their receptors in MC3T3-E1 cells.	IL17A IL17RA	3.66e-06	2	67	2	20497006
Pubmed	The IL-17A/IL-17RA axis in pulmonary defence and immunopathology.	IL17A IL17RA	3.66e-06	2	67	2	27033174
Pubmed	Crystal structures of interleukin 17A and its complex with IL-17 receptor A.	IL17A IL17RA	3.66e-06	2	67	2	23695682
Pubmed	IL-17 Promotes Differentiation of Splenic LSK- Lymphoid Progenitors into B Cells following Plasmodium yoelii Infection.	IL17A IL17RA	3.66e-06	2	67	2	28733485
Pubmed	Critical role of the interleukin-17/interleukin-17 receptor axis in regulating host susceptibility to respiratory infection with Chlamydia species.	IL17A IL17RA	3.66e-06	2	67	2	19737908
Pubmed	Requirement of interleukin-17A for systemic anti-Candida albicans host defense in mice.	IL17A IL17RA	3.66e-06	2	67	2	15243941
Pubmed	A protective function for interleukin 17A in T cell-mediated intestinal inflammation.	IL17A IL17RA	3.66e-06	2	67	2	19448631
Pubmed	Blockade of IL-17 signaling reverses alcohol-induced liver injury and excessive alcohol drinking in mice.	IL17A IL17RA	3.66e-06	2	67	2	32051339
Pubmed	The transcription factor Rreb1 regulates epithelial architecture, invasiveness, and vasculogenesis in early mouse embryos.	SPRY4 LAMA1 KDR	3.76e-06	16	67	3	33929320
Pubmed	Interleukin-17 is not required for classical macrophage activation in a pulmonary mouse model of Cryptococcus neoformans infection.	IL17A IL17RA	1.10e-05	3	67	2	20921149
Pubmed	Candida albicans-specific Th17 cell-mediated response contributes to alcohol-associated liver disease.	IL17A IL17RA	1.10e-05	3	67	2	36893735
Pubmed	The flavonoid cyanidin blocks binding of the cytokine interleukin-17A to the IL-17RA subunit to alleviate inflammation in vivo.	IL17A IL17RA	1.10e-05	3	67	2	28223414
Pubmed	TNF-alpha regulates corneal Langerhans cell migration.	TNFRSF1B IL1R1	1.10e-05	3	67	2	10201952
Pubmed	Topical neutralization of interleukin-17 during experimental Pseudomonas aeruginosa corneal infection promotes bacterial clearance and reduces pathology.	IL17A IL17RA	1.10e-05	3	67	2	22802348
Pubmed	DNA polymerases η and κ bypass N2-guanine-O6-alkylguanine DNA alkyltransferase cross-linked DNA-peptides.	MGMT POLK	1.10e-05	3	67	2	34461101
Pubmed	IL-17 regulates systemic fungal immunity by controlling the functional competence of NK cells.	IL17A IL17RA	1.10e-05	3	67	2	24412614
Pubmed	Requirement of IL-17RA in Con A induced hepatitis and negative regulation of IL-17 production in mouse T cells.	IL17A IL17RA	1.10e-05	3	67	2	19017936
Pubmed	Morphine compromises bronchial epithelial TLR2/IL17R signaling crosstalk, necessary for lung IL17 homeostasis.	IL17A IL17RA	1.10e-05	3	67	2	26072707
Pubmed	Genetic epistasis of IL23/IL17 pathway genes in Crohn's disease.	IL17A IL17RA	1.10e-05	3	67	2	19235914
Pubmed	Macrophages participate in IL-17-mediated inflammation.	IL17A IL17RA	1.10e-05	3	67	2	22161142
Pubmed	The IL-17A/IL-17RA axis plays a proatherogenic role via the regulation of aortic myeloid cell recruitment.	IL17A IL17RA	1.10e-05	3	67	2	22302786
Pubmed	Role of IL-17A on resolution of pulmonary C. neoformans infection.	IL17A IL17RA	1.10e-05	3	67	2	21359196
Pubmed	IL-17 Receptor Signaling through IL-17A or IL-17F Is Sufficient to Maintain Innate Response and Control of Helicobacter pylori Immunopathogenesis.	IL17A IL17RA	1.10e-05	3	67	2	35144998
Pubmed	Divergent functions of IL-17-family cytokines in DSS colitis: Insights from a naturally-occurring human mutation in IL-17F.	IL17A IL17RA	1.10e-05	3	67	2	34587561
Pubmed	IL-17 constrains natural killer cell activity by restraining IL-15-driven cell maturation via SOCS3.	IL17A IL17RA	1.10e-05	3	67	2	31405974
Pubmed	IL-17 promotes tumor development through the induction of tumor promoting microenvironments at tumor sites and myeloid-derived suppressor cells.	IL17A IL17RA	1.10e-05	3	67	2	20118280
Pubmed	IL-1 and TNF receptor-deficient mice show decreased inflammation in an immune complex model of uveitis.	TNFRSF1B IL1R1	1.10e-05	3	67	2	10509653
Pubmed	IL-17A neutralizing antibody attenuates eosinophilic meningitis caused by Angiostrongylus cantonensis by involving IL-17RA/Traf6/NF-κB signaling.	IL17A IL17RA	1.10e-05	3	67	2	31415761
Pubmed	Brucella abortus-infected macrophages modulate T lymphocytes to promote osteoclastogenesis via IL-17.	IL17A IL17RA	1.10e-05	3	67	2	22901753
Pubmed	Early MyD88-dependent induction of interleukin-17A expression during Salmonella colitis.	IL17A IL17RA	1.10e-05	3	67	2	21576324
Pubmed	IL-17 promotes neutrophil entry into tumor-draining lymph nodes following induction of sterile inflammation.	IL17A IL17RA	1.10e-05	3	67	2	24026079
Pubmed	Role of IL-17A, IL-17F, and the IL-17 receptor in regulating growth-related oncogene-alpha and granulocyte colony-stimulating factor in bronchial epithelium: implications for airway inflammation in cystic fibrosis.	IL17A IL17RA	1.10e-05	3	67	2	15972674
Pubmed	Intrahepatic innate lymphoid cells secrete IL-17A and IL-17F that are crucial for T cell priming in viral infection.	IL17A IL17RA	1.10e-05	3	67	2	24600029
Pubmed	Genomic profiling of tumor necrosis factor alpha (TNF-alpha) receptor and interleukin-1 receptor knockout mice reveals a link between TNF-alpha signaling and increased severity of 1918 pandemic influenza virus infection.	TNFRSF1B IL1R1	1.10e-05	3	67	2	20926563
Pubmed	Low levels of tumor necrosis factor alpha increase tumor growth by inducing an endothelial phenotype of monocytes recruited to the tumor site.	KDR TNFRSF1B	1.10e-05	3	67	2	19118019
Pubmed	IL-17A promotes macrophage effector mechanisms against Trypanosoma cruzi by trapping parasites in the endolysosomal compartment.	IL17A IL17RA	1.10e-05	3	67	2	23182712
Pubmed	Interleukin-1 and tumor necrosis factor receptor signaling is not required for bacteria-induced osteoclastogenesis and bone loss but is essential for protecting the host from a mixed anaerobic infection.	TNFRSF1B IL1R1	1.10e-05	3	67	2	10595943
Pubmed	IL-17A controls IL-17F production and maintains blood neutrophil counts in mice.	IL17A IL17RA	1.10e-05	3	67	2	19542376
Pubmed	IL-17 mediated inflammation promotes tumor growth and progression in the skin.	IL17A IL17RA	1.10e-05	3	67	2	22359662
Pubmed	The promoter hypermethylation status of GATA6, MGMT, and FHIT in glioblastoma.	MGMT FHIT	1.10e-05	3	67	2	21928112
Pubmed	Deletion of IL-17ra in osteoclast precursors increases bone mass by decreasing osteoclast precursor abundance.	IL17A IL17RA	1.10e-05	3	67	2	34973492
Pubmed	Association between IL-17A, IL-17F and IL-17RA gene polymorphisms and susceptibility to psoriasis and psoriatic arthritis: a meta-analysis.	IL17A IL17RA	1.10e-05	3	67	2	34705056
Pubmed	Cigarette smoke affects IL-17A, IL-17F and IL-17 receptor expression in the lung tissue: Ex vivo and in vitro studies.	IL17A IL17RA	1.10e-05	3	67	2	26198032
Pubmed	Interleukin-17A Serves a Priming Role in Autoimmunity by Recruiting IL-1β-Producing Myeloid Cells that Promote Pathogenic T Cells.	IL17A IL17RA	1.10e-05	3	67	2	32023490
Pubmed	Polymorphisms within Genes Coding for IL-17A and F and Their Receptor as Clinical Hallmarks in Ankylosing Spondylitis.	IL17A IL17RA	1.10e-05	3	67	2	34744511
Pubmed	Mouse CD11b+Gr-1+ myeloid cells can promote Th17 cell differentiation and experimental autoimmune encephalomyelitis.	IL17A IL1R1	1.10e-05	3	67	2	23034169
Pubmed	MCPIP1 Endoribonuclease Activity Negatively Regulates Interleukin-17-Mediated Signaling and Inflammation.	IL17A IL17RA	1.10e-05	3	67	2	26320658
Pubmed	Conformational dynamics in interleukin 17A and 17F functional complexes is a key determinant of receptor A affinity and specificity.	IL17A IL17RA	1.10e-05	3	67	2	33706174
Pubmed	Regulation of Inflammation by IL-17A and IL-17F Modulates Non-Alcoholic Fatty Liver Disease Pathogenesis.	IL17A IL17RA	1.10e-05	3	67	2	26895034
Pubmed	Development of allergen-induced airway inflammation in the absence of T-bet regulation is dependent on IL-17.	IL17A IL17RA	1.10e-05	3	67	2	19783683
Pubmed	Severity of elastase-induced emphysema is decreased in tumor necrosis factor-alpha and interleukin-1beta receptor-deficient mice.	TNFRSF1B IL1R1	1.10e-05	3	67	2	11796828
Pubmed	Chronic mucocutaneous candidiasis in humans with inborn errors of interleukin-17 immunity.	IL17A IL17RA	1.10e-05	3	67	2	21350122
Pubmed	Role of IL-17 Variants in Preeclampsia in Chinese Han Women.	IL17A IL17RA	1.10e-05	3	67	2	26451724
Pubmed	IL-17 integrates multiple self-reinforcing, feed-forward mechanisms through the RNA binding protein Arid5a.	IL17A IL17RA	1.10e-05	3	67	2	30301788
Pubmed	Interleukin-17 contributes to generation of Th1 immunity and neutrophil recruitment during Chlamydia muridarum genital tract infection but is not required for macrophage influx or normal resolution of infection.	IL17A IL17RA	1.10e-05	3	67	2	21149587
Pubmed	ORF8 contributes to cytokine storm during SARS-CoV-2 infection by activating IL-17 pathway.	IL17A IL17RA	1.10e-05	3	67	2	33723527
GeneFamily	WD repeat domain containing\|BEACH domain containing	NBEAL1 NBEAL2	1.88e-04	9	42	2	1230
GeneFamily	WD repeat domain containing	PREB NBEAL1 NBEAL2 HERC1	3.13e-03	262	42	4	362
GeneFamily	CD molecules\|I-set domain containing\|Immunoglobulin like domain containing\|Interleukin receptors\|TIR domain containing	IL17RA IL1R1	4.28e-03	42	42	2	602
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	KDR IL1R1 MYBPC3	6.17e-03	161	42	3	593
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	ZNF366 MFSD6L PCDH12 SBK2	7.46e-06	84	66	4	5d5e519a6652029b9f5275c8e648bbb123fd07b9
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)-\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	ZNF366 MFSD6L PCDH12 SBK2	7.46e-06	84	66	4	f7ce09c6fb2795b7aecabce00cb9830b3c1a7d0e
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)--\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	ZNF366 MFSD6L PCDH12 SBK2	7.46e-06	84	66	4	2b477de422a9f6a8474cba05094577b88236a4f0
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL15A1 ZNF366 SPRY4 KDR RYR2	7.70e-06	183	66	5	dc19857b66dcadbf7c87de91f7b1f4e8ef2857ed
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL15A1 ZNF366 SPRY4 KDR RYR2	7.70e-06	183	66	5	4759560e5b4f4e5a00e5f933e3451a27c7c4aefe
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid-Endo-Endothelial-Endo_L2-5_CLDN5\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	STARD8 ZNF366 KDR TNFRSF1B HERC2P3	8.34e-06	186	66	5	422d24e3e1a9397bb7d5c7ef75de2fd7ae8e136d
ToppCell	droplet-Liver-Hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPRY4 KDR PCDH12 CYB5R2 EBF4	8.34e-06	186	66	5	90d53c2597a9f3a2b39afba75adfc54f1ca0a4db
ToppCell	droplet-Liver-Hepatocytes-24m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPRY4 KDR PCDH12 CYB5R2 EBF4	8.34e-06	186	66	5	2cae34336f184f971f7c8684cc27c23a4e7369ed
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid-Endo\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	STARD8 ZNF366 KDR TNFRSF1B HERC2P3	8.34e-06	186	66	5	65da0666a10a59f8cc379589860a2e98fe487754
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid-Endo-Endothelial\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	STARD8 ZNF366 KDR TNFRSF1B HERC2P3	8.34e-06	186	66	5	dc84fef1ca2f5d5d818b76a3321559e87d1c4a4d
ToppCell	PCW_05-06-Endothelial-Endothelial_immature-endo_immature_arterial1_(12)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	COL15A1 ZNF366 KDR TNFRSF1B PCDH12	8.78e-06	188	66	5	b294d6658e79328bd6fa33223e8c70117ba9789b
ToppCell	3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-cycling_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	STARD8 COL15A1 ZNF366 KDR PCDH12	8.78e-06	188	66	5	5d166d9e71632edd059ff0a9f66f8763f259d40a
ToppCell	droplet-Liver-Hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPRY4 KDR PCDH12 CYB5R2 EBF4	9.01e-06	189	66	5	ce5b3d53c9a5457a5a02b221dee18334b5eaf8b7
ToppCell	10x5'v1-week_12-13-Endothelial-stroma-tip_EC\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	COL15A1 ZNF366 SPRY4 KDR PCDH12	9.48e-06	191	66	5	cf1a67b7c0d5c0dc5d4d59faf9d9b1a3a1fb00e0
ToppCell	facs-Liver-Non-hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STARD8 SPRY4 KDR PCDH12 SYDE1	1.02e-05	194	66	5	c8b9551b93a5aed62154b487db90130604a6125c
ToppCell	PCW_05-06-Endothelial\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	COL15A1 ZNF366 KDR TNFRSF1B PCDH12	1.02e-05	194	66	5	00291c62795a55a7e63b1db10c139d6a3298e55e
ToppCell	PCW_05-06-Endothelial-Endothelial_immature\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	COL15A1 ZNF366 KDR TNFRSF1B PCDH12	1.02e-05	194	66	5	9bd25ea57f2da27bd200d1a8bf797fec77d172c7
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-1m-Neuroepithelial\|1m / Sample Type, Dataset, Time_group, and Cell type.	COL15A1 NBEAL1 KDR CYB5R2 EBF4	1.18e-05	200	66	5	fe15fb050852c187f6f17fb4f6172e69fe7d74a4
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-1m-Neuroepithelial-Proteoglycan-expressing_cell\|1m / Sample Type, Dataset, Time_group, and Cell type.	COL15A1 NBEAL1 KDR CYB5R2 EBF4	1.18e-05	200	66	5	d0a4c3bf9c5211defb4c1d0b6653833cccbd29ee
ToppCell	E16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-matrix_-_immature_1\|E16.5-samps / Age Group, Lineage, Cell class and subclass	PREB ABCA4 LRRC27 DNAJB5	2.67e-05	116	66	4	f32f7eddfe33adb3b5cf7c34667a481a305c5163
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DZANK1 SALL3 OTUD7A FHIT	5.57e-05	140	66	4	7ca49bd7ba9381e75c10f888775df17e5d46804d
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DZANK1 SALL3 OTUD7A FHIT	5.57e-05	140	66	4	1a31bc33d5723b9bc528cc0047ca5f4c80531c7a
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c6-FGF23\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	STARD8 COL15A1 DOCK8 KDR	7.67e-05	152	66	4	0652ee3443e6fbb679d2c4f326239ae7c803f924
ToppCell	E18.5-samps-Endothelial-Mature_fetal_endothelial-endothelial_cells_B\|E18.5-samps / Age Group, Lineage, Cell class and subclass	DCP1B ZNF366 KDR PCDH12	1.00e-04	163	66	4	d6f9b7280c44d120df5a72dfc2ebb26ffbb5752b
ToppCell	facs-Heart-LA-24m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA1 RYR2 SBK2 MYBPC3	1.08e-04	166	66	4	c43aec09578975df8984886993d15b42a10190c8
ToppCell	facs-Heart-LA-24m-Mesenchymal-atrial_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA1 RYR2 SBK2 MYBPC3	1.08e-04	166	66	4	829a8998ce68739a58202851afd73e049ab0f84f
ToppCell	Endothelial-B-Donor_04\|World / lung cells shred on cell class, cell subclass, sample id	ABCA4 KDR PCDH12 RYR2	1.10e-04	167	66	4	6a03d16165e0b003092c39972928981abd4a75aa
ToppCell	356C-Myeloid-Monocyte-CD16+_Monocyte\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	DUOX1 SMYD5 DOLPP1 DNAJB5	1.10e-04	167	66	4	7e61c5d2cdcfa6a2e3484b3994aec6b64ad75f07
ToppCell	droplet-Marrow-nan-24m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NBEAL2 IL17RA SSH2 TNFRSF1B	1.13e-04	168	66	4	e979a4fbeb9f21048b47d69e6da75c57650697f2
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	STARD8 ZNF366 KDR PCDH12	1.15e-04	169	66	4	41ad349806b279fbe1374b7e3cc7f146a11adb44
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	STARD8 ZNF366 KDR PCDH12	1.15e-04	169	66	4	42782c61592742190ab0cba8a94f8bdf9c278f90
ToppCell	droplet-Kidney-nan-3m-Epithelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL15A1 SPRY4 KDR PCDH12	1.24e-04	172	66	4	073a503dc922e3e3ac3528e249b0f8b74402110b
ToppCell	356C-Myeloid-Monocyte-CD16+_Monocyte\|Monocyte / Donor, Lineage, Cell class and subclass (all cells)	DUOX1 SMYD5 DOLPP1 DNAJB5	1.24e-04	172	66	4	9dca1542145d88559527db7e0f6ad150df59ca2d
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-cycling_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL15A1 ZNF366 KDR SLC4A5	1.29e-04	174	66	4	42735f6a8e5ec36dd3d35aceea6d37cf3eaa1871
ToppCell	droplet-Marrow-nan-3m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STARD8 DOCK8 SSH2 TNFRSF1B	1.32e-04	175	66	4	cf53a15bfb37b6019e7052ffdf594a9ac040900e
ToppCell	NS-moderate-d_07-13-Lymphoid-NK\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	COL15A1 OTUD7A KDR SYDE1	1.32e-04	175	66	4	f6cd24d22f62469319f9d244e3e5de527d3d4d94
ToppCell	droplet-Fat-SCAT-30m-Lymphocytic-T_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL17A NBEAL2 SMYD5 FHIT	1.38e-04	177	66	4	baf78a8dad55f124f56585f88b10b58c0269680f
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Mucinous_Colon_Adenocarcinoma-10\|TCGA-Colorectal / Sample_Type by Project: Shred V9	STARD8 DOCK8 ZNF366 PCDH12	1.44e-04	179	66	4	cc079ba015326dccde955c5eafa3e4a2e40de192
ToppCell	5'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-arterial_capillary\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL15A1 SPRY4 KDR PCDH12	1.47e-04	180	66	4	755050226eeb1991ee7f0d15e39d0458f3e4a791
ToppCell	3'-Adult-SmallIntestine-Endothelial-blood_vessel_EC-arterial_capillary\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL15A1 ZNF366 SPRY4 KDR	1.47e-04	180	66	4	efc4c5a4dea456527526bbfd88cf70d803893671
ToppCell	PCW_05-06-Endothelial-Endothelial_immature-endo_immature3_(11)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	ZNF366 KDR TNFRSF1B PCDH12	1.47e-04	180	66	4	7d4cb0ab9f96088cbc5db3096d884a1e5ce4cb5d
ToppCell	5'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL15A1 ZNF366 KDR PCDH12	1.50e-04	181	66	4	7d7d1edeae4e0ebe40b324d1231cd26e27ba9d42
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-venous_capillary\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	STARD8 COL15A1 ZNF366 KDR	1.54e-04	182	66	4	63b41b538b26bc899558807fd035e543611f8c52
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Mesenchymal-Mes-Pericyte-Peri_L1-6_MUSTN1\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	STARD8 KDR SYDE1 CYB5R2	1.54e-04	182	66	4	406abe0e2958c73ff0f8bfbf7e6183dd6a53db0f
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Mesenchymal-Mes-Pericyte\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	STARD8 KDR SYDE1 CYB5R2	1.54e-04	182	66	4	a71054800e7696ae39b03b11aac2991fb5d54fad
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Endothelial_Myeloid-Endo-Endothelial\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF366 KDR HERC2P3 SYDE1	1.57e-04	183	66	4	6cdadb3ece45a94a2915063aa461048e1d371ccd
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Endothelial_Myeloid-Endo\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF366 KDR HERC2P3 SYDE1	1.57e-04	183	66	4	c7fc96ac1d5d31ccefe0c1fc6ec76c7d8607a172
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Endothelial_Myeloid-Endo-Endothelial-Endo_L2-5_CLDN5\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF366 KDR HERC2P3 SYDE1	1.57e-04	183	66	4	8714d3e7663c93cdf9b25b647353572e136f30c3
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA4 LAMA1 RYR2 DNAH1	1.60e-04	184	66	4	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	3'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-cycling_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL15A1 ZNF366 KDR PCDH12	1.60e-04	184	66	4	fa38d6a8709f520a027ad7e3ff783c84187ec467
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA4 LAMA1 RYR2 DNAH1	1.60e-04	184	66	4	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA4 LAMA1 RYR2 DNAH1	1.60e-04	184	66	4	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	5'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC-venous_capillary\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	STARD8 COL15A1 KDR PCDH12	1.60e-04	184	66	4	97e97de52daaff8840f4ee76a94ba5e3f79de7ce
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL15A1 ZNF366 KDR PCDH12	1.60e-04	184	66	4	a12a6a481e78adc62da1904431f62b119f70b15f
ToppCell	E12.5-Endothelial-capillary_endothelial_cell\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ABCA4 COL15A1 KDR PCDH12	1.63e-04	185	66	4	e005d3c01a908157f780bbc1d53dd2ed814a39d2
ToppCell	E12.5-Endothelial-capillary_endothelial_cell-capillary_endothelial_cell\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ABCA4 COL15A1 KDR PCDH12	1.63e-04	185	66	4	0bccc424d0466f7f82baa00127c733640a2d50fb
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Endothelial_Myeloid-Endo-Endothelial\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF366 KDR TNFRSF1B HERC2P3	1.63e-04	185	66	4	03df43e9c2ce4ec24ffed8e4e2993f94ba951c8b
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Endothelial_Myeloid-Endo\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF366 KDR TNFRSF1B HERC2P3	1.63e-04	185	66	4	de2c24719946d5a37a982d816776cea7f3984c49
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL15A1 KDR TNFRSF1B PCDH12	1.63e-04	185	66	4	602536a3308a848f106adcb0a83530997440c8f4
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Endothelial_Myeloid-Endo-Endothelial-Endo_L2-5_CLDN5\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF366 KDR TNFRSF1B HERC2P3	1.63e-04	185	66	4	dbdbd6593cd98550238519746bb45fbf0617550b
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL15A1 KDR TNFRSF1B PCDH12	1.70e-04	187	66	4	0ef82111b9049cc7ee78d64d240e1f10ab14d6b6
ToppCell	PCW_07-8.5-Endothelial-Endothelial_mature-endo_capillary_(2)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	COL15A1 ZNF366 KDR PCDH12	1.70e-04	187	66	4	106f50ad85a92403037214f0e94702230284837f
ToppCell	3'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC-arterial_capillary\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL15A1 ZNF366 KDR PCDH12	1.70e-04	187	66	4	50d5730e2cd4951d3ad0641fc81ae9f6ddabafe7
ToppCell	wk_08-11-Endothelial-Blood_vessel_endothelial-GRIA2+_arterial_endo\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	COL15A1 KDR TNFRSF1B PCDH12	1.70e-04	187	66	4	a27aa97aa6508a3ffe92c2b6bb0511a95650a390
ToppCell	PCW_07-8.5-Endothelial-Endothelial_immature-endo_immature_arterial2_(6)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	COL15A1 KDR TNFRSF1B PCDH12	1.70e-04	187	66	4	29b2e2be26a9d72b154760e47acf61cfe2f45fa7
ToppCell	droplet-Kidney-KIDNEY-1m-Endothelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL15A1 SPRY4 KDR PCDH12	1.74e-04	188	66	4	51c6796a9488c056a10d048082015342c2e037f9
ToppCell	droplet-Kidney-KIDNEY-1m-Endothelial-kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL15A1 SPRY4 KDR PCDH12	1.74e-04	188	66	4	b651024d58ed1bcfe0d80b21755f8bf709eda81f
ToppCell	PCW_05-06-Endothelial-Endothelial_immature-endo_immature4_(5)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	COL15A1 ZNF366 KDR PCDH12	1.74e-04	188	66	4	b9c5d573fc5ab0f7f38c55d006f9576634b05462
ToppCell	3'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL15A1 ZNF366 KDR PCDH12	1.77e-04	189	66	4	1d660bceee449aebf12fc9af4c74af246837b27a
ToppCell	Non-neuronal-Non-dividing-OPC\|World / Primary Cells by Cluster	LIMA1 SALL3 SPRY4 FHIT	1.77e-04	189	66	4	13848a031ab896b4b24c8319e4745b9b17ff9cfd
ToppCell	3'-GW_trimst-1-LargeIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL15A1 ZNF366 KDR PCDH12	1.77e-04	189	66	4	b5fa3a619e3b554a1a45a551c9b6369075fe5615
ToppCell	Non-neuronal-Non-dividing-OPC-OPC\|World / Primary Cells by Cluster	LIMA1 SALL3 SPRY4 FHIT	1.77e-04	189	66	4	ddf5be73912570c32c50f4ac2902da9b590526f8
ToppCell	Non-neuronal-Non-dividing-OPC-OPC-30\|World / Primary Cells by Cluster	LIMA1 SALL3 SPRY4 FHIT	1.77e-04	189	66	4	313d165fad541ec6e8dd524b88856e2c93eeb681
ToppCell	PCW_05-06-Endothelial-Endothelial_cycling-endo_proliferating1_(10)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	ZNF366 KDR TNFRSF1B PCDH12	1.81e-04	190	66	4	9a2244c3973aee7270646bf00db7727edb9decc5
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-cycling_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL15A1 ZNF366 KDR PCDH12	1.81e-04	190	66	4	d4aefae2d3164db6a9e953c54af0151501e9d1da
ToppCell	PCW_05-06-Endothelial-Endothelial_immature-endo_immature_arterial2_(6)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	COL15A1 KDR TNFRSF1B PCDH12	1.85e-04	191	66	4	e3fc5c92491b6e334abffbf085c00a0b5fa1aed2
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic-Non-classical_Monocyte\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK8 IL17RA SSH2 TNFRSF1B	1.85e-04	191	66	4	47a2afc4102199b4bc76bd01b2967c8016186462
ToppCell	PCW_07-8.5-Endothelial-Endothelial_immature-endo_immature3_(11)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	COL15A1 ZNF366 KDR PCDH12	1.88e-04	192	66	4	7dbe3117a0f58ff2e838963d49f788a59a4351d7
ToppCell	3'-GW_trimst-1-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL15A1 KDR TNFRSF1B PCDH12	1.88e-04	192	66	4	1f35efb0765e05f7f9c881849953bef3965be25a
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL15A1 KDR TNFRSF1B PCDH12	1.88e-04	192	66	4	5a0615fdc217554ccd611504b16e5d97628e207d
ToppCell	facs-Liver-Non-hepatocytes-24m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STARD8 SPRY4 KDR PCDH12	1.88e-04	192	66	4	d525f7f088a53110912600a7c9f6d33b9270d534
ToppCell	facs-Liver-Non-hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STARD8 SPRY4 KDR PCDH12	1.88e-04	192	66	4	2bfac6b3956265205ca47d06888851ed68b65999
ToppCell	3'-GW_trimst-1-LargeIntestine-Endothelial-blood_vessel_EC-cycling_EC\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL15A1 ZNF366 KDR PCDH12	1.92e-04	193	66	4	807fa1443b3c883cb318c71f4fca3c41d58f4910
ToppCell	droplet-Pancreas-Endocrine-18m-Endothelial-endothelial_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL15A1 SPRY4 KDR PCDH12	1.92e-04	193	66	4	5d42979d811ee13a07dee08a3743a90776017cb4
ToppCell	droplet-Pancreas-Endocrine-18m-Endothelial-endothelial_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL15A1 SPRY4 KDR PCDH12	1.92e-04	193	66	4	95e64b9580d30c28702639a043a8b72ce1cadeb6
ToppCell	droplet-Liver-LIVER_HEP-30m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STARD8 SALL3 KDR PCDH12	1.92e-04	193	66	4	826b8dd801298b3e0cd76232feae5a14026b8806
ToppCell	PCW_07-8.5-Endothelial-Endothelial_immature-endo_immature4_(5)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	COL15A1 ZNF366 KDR PCDH12	1.92e-04	193	66	4	72d20ee257149b238016b44d183ce3fc24b8f621
ToppCell	droplet-Pancreas-Endocrine-18m-Endothelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL15A1 SPRY4 KDR PCDH12	1.92e-04	193	66	4	97c0730aad9135ac681250b3871cc094a28f80a7
ToppCell	PCW_07-8.5-Endothelial-Endothelial_immature-endo_immature_arterial1_(12)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	COL15A1 ZNF366 KDR PCDH12	1.92e-04	193	66	4	d338a7c0585b69947c37f44aa0381619493e31ea
ToppCell	URO\|World / Disease, Lineage and Cell Type	NBEAL2 IL17RA SSH2 TNFRSF1B	1.92e-04	193	66	4	421dc0996c6c973f88e90197b651255ae4dd13a2
ToppCell	COVID-19-Heart-CM_+_EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	DCP1B FHIT RYR2 MYBPC3	1.92e-04	193	66	4	dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCell	droplet-Liver-LIVER_HEP-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STARD8 SALL3 KDR PCDH12	1.92e-04	193	66	4	87d3a577d37fb0cb4b6313c596310de452bc3872
ToppCell	3'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL15A1 ZNF366 KDR PCDH12	1.92e-04	193	66	4	1b69f92c6a7a2516e393d3f3c371407ec791343d
ToppCell	PCW_07-8.5-Endothelial-Endothelial_cycling-endo_proliferating3_(3)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	COL15A1 ZNF366 KDR PCDH12	1.92e-04	193	66	4	72128ece598070f8e752a0691e024e26ab364989
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell-D231\|Adult / Lineage, Cell type, age group and donor	LIMA1 COL15A1 IL1R1 RYR2	1.92e-04	193	66	4	ef2f456c094e6e3c6ee81e0668c953cb8d0e1c0a
ToppCell	PCW_07-8.5-Endothelial-Endothelial_immature-endo_immature1_(0)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	COL15A1 ZNF366 KDR PCDH12	1.96e-04	194	66	4	2e3a64bda7c76fd0c99e93de0215f236e8045d83
ToppCell	PCW_13-14-Endothelial-Endothelial_mature-endo_capillary_(2)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	COL15A1 ZNF366 KDR PCDH12	1.96e-04	194	66	4	3c31ac44e8cf4eca3ba7b8bfc05ad3e96a970956
ToppCell	10x5'v1-week_17-19-Endothelial-stroma\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	SPRY4 KDR IL1R1 SYDE1	1.96e-04	194	66	4	953578102ffc7b612ee8fce45e414750800fef5d
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes-Non-classical_monocytes_L.1.2.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DOCK8 IL17RA SSH2 TNFRSF1B	1.96e-04	194	66	4	dfe0ece81922bfd7c6673726d3ea2365cbdb5513
ToppCell	10x5'v1-week_14-16-Endothelial-stroma-proliferating_EC\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	ABCA4 COL15A1 KDR PCDH12	1.96e-04	194	66	4	8a4be91414a2e69dd410aa75791f16008204c9a1
Disease	macular degeneration (is_implicated_in)	IL17A ABCA4 KDR	2.74e-05	27	64	3	DOID:4448 (is_implicated_in)
Disease	granulosa cell tumor (is_implicated_in)	MGMT FHIT	2.77e-05	4	64	2	DOID:2999 (is_implicated_in)
Disease	Pneumonia	IL17A TNFRSF1B IL1R1	2.23e-04	54	64	3	C0032285
Disease	Pneumonitis	IL17A TNFRSF1B IL1R1	2.23e-04	54	64	3	C3714636
Disease	Lobar Pneumonia	IL17A TNFRSF1B IL1R1	2.23e-04	54	64	3	C0032300
Disease	Experimental Lung Inflammation	IL17A TNFRSF1B IL1R1	2.23e-04	54	64	3	C0887898
Disease	Brain Ischemia	IL17A IL17RA TNFRSF1B	3.05e-04	60	64	3	C0007786
Disease	Cerebral Ischemia	IL17A IL17RA TNFRSF1B	3.05e-04	60	64	3	C0917798
Disease	Allergic Reaction	IL17A TNFRSF1B IL1R1	3.52e-04	63	64	3	C1527304
Disease	Hypersensitivity	IL17A TNFRSF1B IL1R1	3.69e-04	64	64	3	C0020517
Disease	urinary bladder cancer (is_implicated_in)	MGMT KDR FHIT	6.11e-04	76	64	3	DOID:11054 (is_implicated_in)
Disease	ankylosing spondylitis (is_implicated_in)	IL17A TNFRSF1B	7.73e-04	19	64	2	DOID:7147 (is_implicated_in)
Disease	glioblastoma (is_implicated_in)	MGMT KDR	1.24e-03	24	64	2	DOID:3068 (is_implicated_in)
Disease	chronic obstructive pulmonary disease (is_marker_for)	IL17A KDR TNFRSF1B	1.24e-03	97	64	3	DOID:3083 (is_marker_for)
Disease	Micronuclei, Chromosome-Defective	MGMT POLK	1.46e-03	26	64	2	C1449861
Disease	Micronuclei, Genotoxicant-Induced	MGMT POLK	1.46e-03	26	64	2	C1449862

Protein segments in the cluster

Peptide	Gene	Start	Entry
RVIPLPCNDVIKPGT	DNAJB5	286	O75953
TVLRPQLGLHPNPEC	LINC01590	21	Q5TEZ4
NVNPRHPCLGPREKA	ABCA4	1296	P78363
QTPCQLLKEPHPPRL	NBEAL1	2271	Q6ZS30
ILVCGPPPLIQTAAH	CYB5R2	246	Q6BCY4
PPAPGQDLVILKRNH	PAAT	51	Q9H8K7
VLQRHGVPPPCKPLA	PTPN23	1456	Q9H3S7
DLGPNPIPAHCKVLI	PCDH12	326	Q9NPG4
GHKEPCRPVLVYLQP	DUOX1	651	Q9NRD9
HCPGIKVVIPRSPFQ	BCKDHB	206	P21953
QQILCPKPVHVRPPM	PATL1	206	Q86TB9
AVAKLEPHLQPRGQP	IL17RA	646	Q96F46
IKNVIQEPRPCGGPH	DOLPP1	76	Q86YN1
KENVPPGPEVCITHQ	LIMA1	306	Q9UHB6
QQARHPLILPQELPC	NUDT18	171	Q6ZVK8
PGPLLCVLVHVLPQV	ERVS71-1	401	P61550
GNPVPILIPCHRVVC	MGMT	136	P16455
EVVPLPQQVLCLKGP	HERC1	46	Q15751
HPQPIDPLLKNCIGD	CAND1	996	Q86VP6
LVPPVDKNRVHFPCN	MFSD6L	96	Q8IWD5
CLVPNTPLHLKGLPV	MS4A10	206	Q96PG2
RCPKPTPQQISHIAG	POU5F2	231	Q8N7G0
PQPGHKVERPCLQRQ	OTUD7A	91	Q8TE49
QQEILVLRREPPHCP	IL17A	116	Q16552
GGQLIVPIIPLCPEH	OXER1	6	Q8TDS5
RHSPPIEKQLCPAIQ	DCP1B	281	Q8IZD4
QVPFQVLPGQHPRKI	DNAH1	176	Q9P2D7
VNRKPVVPGHVLVCP	FHIT	26	P49789
VEIRPVPECPKEHLG	DOCK8	251	Q8NF50
QRLQKVIPRHPGDPE	EBF4	351	Q9BQW3
RCPPIPAHGKEVRQL	LINC00315	51	P59091
QHSIPLGPNVLPVCL	C1RL	346	Q9NZP8
LLVHVCARPEKPPGQ	IDUA	536	P35475
IIPLRVPQPGKANHE	DZANK1	11	Q9NVP4
NIKGAIFPIPVRPHC	COL15A1	951	P39059
PKVGLPQPAVHRCAA	SBK2	151	P0C263
AKPPLRVQHSCPICQ	SALL3	731	Q9BXA9
KNPVPQCPPRLHVQF	RYR2	1576	Q92736
VRPCPLNPNEHKGTI	IL1R1	41	P14778
TGPLPEQCRLMHIQP	MED19	156	A0JLT2
RERPPGQVPLIIQKC	SYDE1	406	Q6ZW31
PRAVRIQPKVVHCQP	SPRY4	126	Q9C004
HLPCRPVKPNIIGEQ	TRMT1L	161	Q7Z2T5
HCPLEFPPQLVVQKG	LRRC27	146	Q9C0I9
KLVEHVPGRPVRNPQ	LAMA1	51	P25391
GQTPCQLLKEPHPTR	NBEAL2	2331	Q6ZNJ1
PPAKCQHQESLGRPR	MIIP	96	Q5JXC2
HVCPLNQLKPLPAVA	HERC2P3	966	Q9BVR0
VLLKPNPLDQTCIHP	SRBD1	816	Q8N5C6
VPGPQHTELACRKAP	STARD8	841	Q92502
TVQIPHKRLRQPPPC	PREB	266	Q9HCU5
IVRHGRPPPCKKQPQ	ZYG11B	726	Q9C0D3
IQLKGDILPNPCHTP	SSH2	766	Q76I76
NTGLPCQIHPSPLKR	SAMD4B	221	Q5PRF9
VKPANACHPIEAPRL	ZNRF4	136	Q8WWF5
IAKRLCPQLIIVPPN	POLK	156	Q9UBT6
RFPDQKECPPIHIGL	SLC4A5	21	Q9BY07
PPIQNACVADKHRPL	RRP36	81	Q96EU6
TPLHLQVPPCQVGIF	TRIM21	396	P19474
HPKRPVLGLECPQSE	SMUG1	121	Q53HV7
HRLPQQGEKPAQCTP	ZNF786	286	Q8N393
QLVCHELIPGGKTIP	UBE3B	856	Q7Z3V4
PHCLQPVASRGKAPQ	ZNF366	26	Q8N895
PLCLQREAKVPHLPA	TNFRSF1B	291	P20333
LPIHVGELPTPVCKN	KDR	591	P35968
PGQVLPHPELCTVRK	SMYD5	91	Q6GMV2
VVPLQHCKIPELPVQ	TMEM39B	61	Q9GZU3
RQEPPKIHLDCPGRI	MYBPC3	641	Q14896