Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontranslation elongation factor activity

EIF5A EIF5A2 EIF5AL1

1.35e-0520473GO:0003746
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

ZNF711 ZNF398 ZNF778 ZNF322 ZNF700 TSHZ2 ZNF569 PRDM16 ZEB2 ZNF433 ZNF197 MYB STAT6

1.52e-0514124713GO:0000981
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

ZNF711 ZNF398 ZNF778 ZNF322 ZNF700 ZNF865 ZNF569 PRDM16 ZEB2 ZNF433 ZNF197 MYB STAT6

2.15e-0514594713GO:0000977
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

ZNF711 ZNF778 ZNF322 ZNF865 ZNF569 PRDM16 ZEB2 ZNF433 ZNF197 MYB STAT6

1.14e-0412444711GO:0000978
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

ZNF711 ZNF778 ZNF322 ZNF865 ZNF569 PRDM16 ZEB2 ZNF433 ZNF197 MYB STAT6

1.38e-0412714711GO:0000987
GeneOntologyMolecularFunctionribosome binding

EIF5A EIF5A2 EIF5AL1 ERI1

1.81e-04120474GO:0043022
GeneOntologyMolecularFunctionDNA-binding transcription activator activity, RNA polymerase II-specific

ZNF778 PRDM16 ZEB2 ZNF433 ZNF197 MYB STAT6

3.12e-04560477GO:0001228
GeneOntologyMolecularFunctionDNA-binding transcription activator activity

ZNF778 PRDM16 ZEB2 ZNF433 ZNF197 MYB STAT6

3.33e-04566477GO:0001216
GeneOntologyMolecularFunctionU6 snRNA binding

EIF5A EIF5AL1

8.10e-0418472GO:0017070
GeneOntologyMolecularFunctiontranslation factor activity, RNA binding

EIF5A EIF5A2 EIF5AL1

1.05e-0385473GO:0008135
GeneOntologyMolecularFunctionribonucleoprotein complex binding

EIF5A EIF5A2 EIF5AL1 ERI1

1.39e-03206474GO:0043021
GeneOntologyMolecularFunctiontranslation regulator activity, nucleic acid binding

EIF5A EIF5A2 EIF5AL1

2.33e-03112473GO:0090079
GeneOntologyBiologicalProcesspositive regulation of translational termination

EIF5A EIF5A2 EIF5AL1

3.37e-084433GO:0045905
GeneOntologyBiologicalProcesspositive regulation of translational elongation

EIF5A EIF5A2 EIF5AL1

8.42e-085433GO:0045901
GeneOntologyBiologicalProcessregulation of translational termination

EIF5A EIF5A2 EIF5AL1

7.03e-079433GO:0006449
GeneOntologyBiologicalProcessregulation of translational elongation

EIF5A EIF5A2 EIF5AL1

3.02e-0614433GO:0006448
GeneOntologyBiologicalProcesstranslational termination

EIF5A EIF5A2 EIF5AL1

5.62e-0617433GO:0006415
GeneOntologyBiologicalProcesspositive regulation of protein-containing complex disassembly

EIF5A EIF5A2 EIF5AL1

8.51e-0541433GO:0043243
GeneOntologyBiologicalProcesspositive regulation of cytosolic calcium ion concentration

EIF5A PLCZ1 EIF5AL1 SLC8A1 AGTR1

9.94e-05224435GO:0007204
GeneOntologyBiologicalProcessamyloid-beta clearance by cellular catabolic process

LRP4 MME

1.18e-048432GO:0150094
GeneOntologyBiologicalProcesscalcium ion import across plasma membrane

TRPV6 SLC8A1 AGTR1

1.37e-0448433GO:0098703
GeneOntologyBiologicalProcesscalcium ion import into cytosol

TRPV6 SLC8A1 AGTR1

1.37e-0448433GO:1902656
GeneOntologyBiologicalProcesscorticospinal tract morphogenesis

SPG11 ZEB2

1.89e-0410432GO:0021957
DomainIF5A_HYPUSINE

EIF5A EIF5A2 EIF5AL1

1.49e-083473PS00302
DomainTransl_elong_IF5A_C

EIF5A EIF5A2 EIF5AL1

1.49e-083473IPR020189
DomainTransl_elong_IF5A

EIF5A EIF5A2 EIF5AL1

1.49e-083473IPR001884
DomaineIF-5a

EIF5A EIF5A2 EIF5AL1

1.49e-083473PF01287
DomainTrans_elong_IF5A_hypusine_site

EIF5A EIF5A2 EIF5AL1

1.49e-083473IPR019769
DomaineIF-5a

EIF5A EIF5A2 EIF5AL1

1.49e-083473SM01376
DomainZINC_FINGER_C2H2_2

ZNF711 ZNF398 ZNF778 ZNF322 ZNF800 ZNF700 ZNF865 TSHZ2 ZNF569 PRDM16 ZEB2 ZNF433 ZNF197

3.72e-087754713PS50157
DomainZINC_FINGER_C2H2_1

ZNF711 ZNF398 ZNF778 ZNF322 ZNF800 ZNF700 ZNF865 TSHZ2 ZNF569 PRDM16 ZEB2 ZNF433 ZNF197

3.84e-087774713PS00028
DomainZnf_C2H2-like

ZNF711 ZNF398 ZNF778 ZNF322 ZNF800 ZNF700 ZNF865 TSHZ2 ZNF569 PRDM16 ZEB2 ZNF433 ZNF197

5.09e-087964713IPR015880
DomainZnf_C2H2

ZNF711 ZNF398 ZNF778 ZNF322 ZNF800 ZNF700 ZNF865 TSHZ2 ZNF569 PRDM16 ZEB2 ZNF433 ZNF197

5.81e-088054713IPR007087
DomainZnF_C2H2

ZNF711 ZNF398 ZNF778 ZNF322 ZNF800 ZNF700 ZNF865 TSHZ2 ZNF569 PRDM16 ZEB2 ZNF433 ZNF197

6.07e-088084713SM00355
Domain-

ZNF711 ZNF398 ZNF778 ZNF322 ZNF800 ZNF700 ZNF865 ZNF569 PRDM16 ZEB2 ZNF433 ZNF197

7.86e-0867947123.30.160.60
DomainZnf_C2H2/integrase_DNA-bd

ZNF711 ZNF398 ZNF778 ZNF322 ZNF800 ZNF700 ZNF865 ZNF569 PRDM16 ZEB2 ZNF433 ZNF197

9.97e-086944712IPR013087
Domainzf-C2H2

ZNF711 ZNF398 ZNF778 ZNF322 ZNF700 ZNF865 TSHZ2 ZNF569 PRDM16 ZNF433 ZNF197

8.72e-076934711PF00096
DomainTranslation_prot_SH3-like

EIF5A EIF5A2 EIF5AL1

9.91e-0617473IPR008991
DomainRib_L2_dom2

EIF5A EIF5A2 EIF5AL1

1.19e-0518473IPR014722
Domain-

EIF5A EIF5A2 EIF5AL1

1.19e-05184732.30.30.30
Domainzf-C2H2_6

ZNF778 ZNF700 ZNF865 ZNF569 PRDM16 ZNF433 ZNF197

1.25e-05314477PF13912
DomainKRAB

ZNF398 ZNF778 ZNF700 ZNF569 ZNF433 ZNF197

2.63e-04358476PS50805
DomainKRAB

ZNF398 ZNF778 ZNF700 ZNF569 ZNF433 ZNF197

2.63e-04358476PF01352
DomainKRAB

ZNF398 ZNF778 ZNF700 ZNF569 ZNF433 ZNF197

3.09e-04369476SM00349
DomainKRAB

ZNF398 ZNF778 ZNF700 ZNF569 ZNF433 ZNF197

3.14e-04370476IPR001909
DomainKOW

EIF5A EIF5A2

3.36e-0411472IPR005824
DomainKOW

EIF5A EIF5A2

3.36e-0411472PF00467
DomainNA-bd_OB-fold

EIF5A EIF5A2 EIF5AL1

1.19e-0383473IPR012340
Domain-

ERI1 POLE

6.23e-03474723.30.420.10
PathwayREACTOME_HYPUSINE_SYNTHESIS_FROM_EIF5A_LYSINE

EIF5A EIF5A2 EIF5AL1

1.40e-075353MM14823
Pubmed

Human eIF5A2 on chromosome 3q25-q27 is a phylogenetically conserved vertebrate variant of eukaryotic translation initiation factor 5A with tissue-specific expression.

EIF5A EIF5A2 EIF5AL1

2.31e-09347311161802
Pubmed

New K50R mutant mouse models reveal impaired hypusination of eif5a2 with alterations in cell metabolite landscape.

EIF5A EIF5A2 EIF5AL1

2.31e-09347336848144
Pubmed

Differential expression of eIF5A-1 and eIF5A-2 in human cancer cells.

EIF5A EIF5A2 EIF5AL1

2.31e-09347316519677
Pubmed

Biological Relevance and Therapeutic Potential of the Hypusine Modification System.

EIF5A EIF5A2 EIF5AL1

2.31e-08547326037925
Pubmed

Comparison of Human Eukaryotic Translation Initiation Factors 5A1 and 5AL1: Identification of Amino Acid Residues Important for EIF5A1 Lysine 50 Hypusination and Its Protein Stability.

EIF5A EIF5AL1

1.79e-06247237047039
Pubmed

Polyamines and eIF5A Hypusination Modulate Mitochondrial Respiration and Macrophage Activation.

EIF5A EIF5AL1

1.79e-06247231130465
Pubmed

Independent roles of eIF5A and polyamines in cell proliferation.

EIF5A EIF5AL1

1.79e-06247215377278
Pubmed

Sequence determination and cDNA cloning of eukaryotic initiation factor 4D, the hypusine-containing protein.

EIF5A EIF5AL1

1.79e-0624722492279
Pubmed

The N-terminal region of eukaryotic translation initiation factor 5A signals to nuclear localization of the protein.

EIF5A EIF5AL1

1.79e-06247217707773
Pubmed

Proteomic analysis of ubiquitin-proteasome effects: insight into the function of eukaryotic initiation factor 5A.

EIF5A EIF5AL1

1.79e-06247212894223
Pubmed

Targeted inhibition of eIF5Ahpu suppresses tumor growth and polarization of M2-like tumor-associated macrophages in oral cancer.

EIF5A EIF5AL1

1.79e-06247237653021
Pubmed

ACACβ gene (rs2268388) and AGTR1 gene (rs5186) polymorphism and the risk of nephropathy in Asian Indian patients with type 2 diabetes.

ACACB AGTR1

1.79e-06247223081748
Pubmed

Identification of a new member of the human eIF-5A gene family.

EIF5A EIF5AL1

1.79e-0624727622067
Pubmed

Eukaryotic initiation factor 5A is a cellular target of the human immunodeficiency virus type 1 Rev activation domain mediating trans-activation.

EIF5A EIF5AL1

1.79e-0624728253832
Pubmed

Eukaryotic initiation factor 4D. Purification from human red blood cells and the sequence of amino acids around its single hypusine residue.

EIF5A EIF5AL1

1.79e-0624723095320
Pubmed

Exosomal EIF5A derived from Lewis lung carcinoma induced adipocyte wasting in cancer cachexia.

EIF5A EIF5AL1

1.79e-06247237743008
Pubmed

Homology modelling of the human eukaryotic initiation factor 5A (eIF-5A).

EIF5A EIF5AL1

1.79e-06247211742107
Pubmed

The unique hypusine modification of eIF5A promotes islet beta cell inflammation and dysfunction in mice.

EIF5A EIF5AL1

1.79e-06247220501948
Pubmed

Deoxyhypusine synthase mutations alter the post-translational modification of eukaryotic initiation factor 5A resulting in impaired human and mouse neural homeostasis.

EIF5A EIF5AL1

5.36e-06347237333770
Pubmed

Combined inhibition of polyamine metabolism and eIF5A hypusination suppresses colorectal cancer growth through a converging effect on MYC translation.

EIF5A EIF5AL1

5.36e-06347236893894
Pubmed

Essential role of eIF5A-1 and deoxyhypusine synthase in mouse embryonic development.

EIF5A EIF5AL1

5.36e-06347221850436
Pubmed

Klf5 down-regulation induces vascular senescence through eIF5a depletion and mitochondrial fission.

EIF5A EIF5AL1

5.36e-06347232817651
Pubmed

Identification and characterization of eukaryotic initiation factor 5A-2.

EIF5A EIF5A2

5.36e-06347214622290
Pubmed

The role of polyamines in supporting growth of mammalian cells is mediated through their requirement for translation initiation and elongation.

EIF5A EIF5AL1

5.36e-06347220181941
Pubmed

Evidences of a role for eukaryotic translation initiation factor 5A (eIF5A) in mouse embryogenesis and cell differentiation.

EIF5A EIF5AL1

5.36e-06347220458750
Pubmed

Subcellular localization of the hypusine-containing eukaryotic initiation factor 5A by immunofluorescent staining and green fluorescent protein tagging.

EIF5A EIF5AL1

5.36e-06347212210765
Pubmed

The transcription factor c-Myb regulates CD8+ T cell stemness and antitumor immunity.

ZEB2 MYB

1.07e-05447230778251
Pubmed

The genomic structure encoding human initiation factor eIF-5A.

EIF5A EIF5AL1

1.07e-0544727545941
Pubmed

The eukaryotic cofactor for the human immunodeficiency virus type 1 (HIV-1) rev protein, eIF-5A, maps to chromosome 17p12-p13: three eIF-5A pseudogenes map to 10q23.3, 17q25, and 19q13.2.

EIF5A EIF5AL1

1.07e-0544727759117
Pubmed

Interactions between angiotensin ll and atrial natriuretic peptide in renomedullary interstitial cells: the role of neutral endopeptidase.

MME AGTR1

1.07e-05447216582578
Pubmed

Expression of eukaryotic initiation factor 5A and hypusine forming enzymes in glioblastoma patient samples: implications for new targeted therapies.

EIF5A EIF5A2

1.07e-05447222927971
Pubmed

DHPS-dependent hypusination of eIF5A1/2 is necessary for TGFβ/fibronectin-induced breast cancer metastasis and associates with prognostically unfavorable genomic alterations in TP53.

EIF5A EIF5A2

1.07e-05447231558321
Pubmed

The post-translational synthesis of a polyamine-derived amino acid, hypusine, in the eukaryotic translation initiation factor 5A (eIF5A).

EIF5A EIF5A2

1.07e-05447216452303
Pubmed

Calcium transport genes are differently regulated in maternal and fetal placenta in the knockout mice of calbindin-D(9k) and -D(28k).

TRPV6 SLC8A1

1.78e-05547222407925
Pubmed

Neuron-specific ablation of eIF5A or deoxyhypusine synthase leads to impairments in growth, viability, neurodevelopment, and cognitive functions in mice.

EIF5A EIF5AL1

1.78e-05547234688659
Pubmed

A census of human transcription factors: function, expression and evolution.

ZNF711 ZNF398 ZNF322 TSHZ2 ZEB2 ZNF197 MYB STAT6

2.67e-0590847819274049
Pubmed

The discoidin domain receptor tyrosine kinases are activated by collagen.

DDR1 MME

2.67e-0564729659899
Pubmed

Immunohistochemical distinction of renal cell carcinoma from other carcinomas with clear-cell histomorphology: utility of CD10 and CA-125 in addition to PAX-2, PAX-8, RCCma, and adipophilin.

MUC16 MME

2.67e-05647225279712
Pubmed

Prediction of the coding sequences of unidentified human genes. XXII. The complete sequences of 50 new cDNA clones which code for large proteins.

FNIP1 SGSM1 TMEM132D

4.60e-055147311853319
Pubmed

Exportin 4: a mediator of a novel nuclear export pathway in higher eukaryotes.

EIF5A EIF5AL1

7.99e-051047210944119
Pubmed

Association of dysfunctional synapse defective 1 (SYDE1) with restricted fetal growth - SYDE1 regulates placental cell migration and invasion.

MME AGTR1

1.86e-041547227917469
Pubmed

Identification of three novel genetic variations associated with electrocardiographic traits (QRS duration and PR interval) in East Asians.

SLC8A1 PRDM16

2.12e-041647225035420
Pubmed

The thiazide-sensitive Na(+)-Cl(-) cotransporter gene, C1784T, and adrenergic receptor-beta3 gene, T727C, may be gene polymorphisms susceptible to the antihypertensive effect of thiazide diuretics.

SLC8A1 AGTR1

2.12e-041647215824464
Pubmed

Role of TIF1alpha as a modulator of embryonic transcription in the mouse zygote.

EIF5A EIF5AL1

2.12e-041647216880268
Pubmed

Deoxyhypusine synthase, an essential enzyme for hypusine biosynthesis, is required for proper exocrine pancreas development.

EIF5A EIF5AL1

2.40e-041747233811703
Pubmed

Human CIA2A-FAM96A and CIA2B-FAM96B integrate iron homeostasis and maturation of different subsets of cytosolic-nuclear iron-sulfur proteins.

EIF5A2 EIF5AL1 POLE

2.42e-048947323891004
Pubmed

Identification of genetic factors associated with susceptibility to angiotensin-converting enzyme inhibitors-induced cough.

MME AGTR1

3.01e-041947221052031
Pubmed

Emergence of the ZNF91 Krüppel-associated box-containing zinc finger gene family in the last common ancestor of anthropoidea.

ZNF778 ZNF569

3.34e-04204727479878
Pubmed

Activation of the c-H-ras proto-oncogene by retrovirus insertion and chromosomal rearrangement in a Moloney leukemia virus-induced T-cell leukemia.

ZNF778 ZNF569

3.34e-04204722542606
Pubmed

The FNIP co-chaperones decelerate the Hsp90 chaperone cycle and enhance drug binding.

CDC37 FNIP1

3.69e-042147227353360
Pubmed

Chromosomal localization of glutamate receptor genes: relationship to familial amyotrophic lateral sclerosis and other neurological disorders of mice and humans.

MME MYB

4.44e-04234728464923
Pubmed

A single-cell time-lapse of mouse prenatal development from gastrula to birth.

MUC16 ZEB2

5.26e-042547238355799
Pubmed

Non-canonical Wnt Signaling through Ryk Regulates the Generation of Somatostatin- and Parvalbumin-Expressing Cortical Interneurons.

CDC37 ZEB2

6.14e-042747231257105
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

ZNF398 LRP4 B4GALNT4 ZNF865 PRDM16 PCNX4 POLE

6.65e-04110547735748872
Pubmed

Gene expression and characterization of clonally derived murine embryonic brown and brite adipocytes.

ACACB PRDM16

7.09e-042947238972757
Pubmed

Genetic polymorphisms in adaptive immunity genes and childhood acute lymphoblastic leukemia.

MME STAT6

7.09e-042947220716621
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

ZNF398 ZNF322 ERI1 ZNF569 PRDM16 MYB

7.36e-0480847620412781
Pubmed

Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.

SLC8A1 NDUFA8 TMEM132D ZEB2 PIP4K2A MYB

7.65e-0481447623251661
Pubmed

Molecular mapping of developing dorsal horn-enriched genes by microarray and dorsal/ventral subtractive screening.

TSHZ2 ZEB2

8.64e-043247216516881
Pubmed

Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.

TSHZ2 MYB

1.03e-033547219862010
Pubmed

Chromatin state signatures associated with tissue-specific gene expression and enhancer activity in the embryonic limb.

EIF5A EIF5AL1

1.09e-033647222421546
Pubmed

Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.

TRPV6 SLC8A1

1.22e-033847230786075
Cytoband19p13.2

CDC37 MUC16 ZNF700 ZNF433

9.09e-0522947419p13.2
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF711 ZNF398 ZNF778 ZNF322 ZNF800 ZNF700 ZNF865 TSHZ2 ZNF569 PRDM16 ZEB2 ZNF433 ZNF197

2.35e-10718341328
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

TSHZ2 ZEB2

3.55e-0415342529
GeneFamilyGuanylate cyclase receptors|DENN/MADD domain containing

FNIP1 DENND2C

1.00e-0325342504
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#1_top-relative-expression-ranked_1000

MUC16 B4GALNT4 MME NEBL TSHZ2 ZNF569 ZEB2

7.49e-06337467gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k1_1000
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#2_top-relative-expression-ranked_1000

ZNF711 MUC16 MME ZNF700 TSHZ2 ZEB2

2.20e-05265466gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k2_1000
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#4_top-relative-expression-ranked_500

MUC16 MME NEBL TSHZ2 ZEB2

8.31e-05207465gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k4_500
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW09-Neuronal-Neuron|GW09 / Sample Type, Dataset, Time_group, and Cell type.

ZNF711 ZNF865 TSHZ2 ZNF197 PIP4K2A MYB

4.72e-081894763717d1148e26ac78a26aea0ca1dbfbb9d3668877
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Degenerative_Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DDR1 TRPV6 SLC8A1 NEBL PRDM16

1.52e-06186475b3358e0fa6d845c81e94d56c8575f016621d28ff
ToppCellNS-control|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MUC16 DDR1 NEBL TSHZ2 DENND2C

2.18e-06200475ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPV6 SLC8A1 SGSM1 PRDM16

2.32e-051584747960337d87afecf2692ab65e5991f052ceddfacc
ToppCell356C-Fibroblasts-Fibroblast-G-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

MME NEBL ZEB2 AGTR1

2.44e-051604740293b244c063a62819690bf22bbc2681f8d15252
ToppCell356C-Fibroblasts-Fibroblast-G|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

MME NEBL ZEB2 AGTR1

2.44e-051604743eaae86fa08f7651021316f8e5811bf48055591e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC8A1 SGSM1 PRDM16 PCNX4

2.75e-051654749bd332e5ede759a00a47728ea5558c215efdd77a
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 DDR1 PLCZ1 NEBL

3.02e-0516947440b557549fe08c5dc9dba359af35993d68d1640a
ToppCell10x_3'_v3-blood_(10x_3'_v3)-hematologic-hematopoietic_progenitor-hematopoietic_stem_cell|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ZNF711 HFM1 PRDM16 MYB

3.09e-051704745bb577e2c4bd275fbe4ee23ff8c007b2fcb90e56
ToppCell10x_3'_v3-blood_(10x_3'_v3)-hematologic-hematopoietic_progenitor|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ZNF711 HFM1 PRDM16 MYB

3.39e-0517447466df78280f657978c4a568010ae7d7943869af90
ToppCelldroplet-Kidney-nan-21m-Epithelial-Epcam____kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDR1 SLC8A1 SGSM1 PRDM16

4.03e-05182474fe4fb213dc0ca482b0f94097fe1b0a51fc2690e2
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Degenerative_Connecting_Tubule_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DDR1 TRPV6 SLC8A1 PRDM16

4.21e-051844749690d4290e70f9bda889754ffb30b0af1f7cb94b
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MUC16 SLC8A1 PRDM16 ZEB2

4.39e-0518647423b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPV6 SLC8A1 NEBL PRDM16

4.58e-051884744154f4787483c7e076e87a187733a9f666742c3d
ToppCellRV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

SLC8A1 ACACB NEBL PRDM16

4.67e-051894745e80c47f63980904c4c1ff02c201b67b456a0974
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TRPV6 SLC8A1 NEBL PRDM16

4.67e-051894748ff3c3232eff9de4b5c9b22ecb82bc509d773f58
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPV6 SLC8A1 NEBL PRDM16

4.67e-0518947490aae7e806882bebfad78a78e9a16cf56af3ecd4
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LRP4 DDR1 ACACB PRDM16

4.77e-0519047407f21386ea6eb23416a537d2250e3042efe93fb0
ToppCelldroplet-Kidney-nan-18m-Epithelial-kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDR1 TRPV6 SLC8A1 ACACB

4.77e-05190474c408d4033a130c0168159a5b6f286fd2b2a9a39d
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TRPV6 SLC8A1 NEBL PRDM16

4.77e-051904744836ea19308d2a96694f12ab0653b7ce7b101d2f
ToppCellLV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

SLC8A1 ACACB NEBL PRDM16

4.77e-05190474de5ef606a002f85c2e0e3a36c1f259d0b85a76ff
ToppCelldroplet-Kidney-nan-18m-Epithelial-Epcam____kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDR1 TRPV6 SLC8A1 ACACB

4.77e-05190474d4910c37045a8b8bb53b37625263bc0a47b6e3f8
ToppCellRV-06._Ventricular_Cardiomyocyte_II|RV / Chamber and Cluster_Paper

SLC8A1 ACACB NEBL PRDM16

4.77e-05190474fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MME TSHZ2 ZEB2 AGTR1

4.87e-05191474fa380a8752de158974b2ae5e741573439719cc0d
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal|E16.5-samps / Age Group, Lineage, Cell class and subclass

LRP4 MME NEBL ZEB2

4.87e-051914743379d145d34f89150f7b06d1340022cfc6b4a6ce
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HMOX2 TSHZ2 ZEB2 AGTR1

5.07e-051934745b602b1702283184bd3943c2a6f2290b7c37e407
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HMOX2 TSHZ2 ZEB2 AGTR1

5.07e-05193474c8c21eee8c6c086dc2faf416669cd4a002870fbe
ToppCellE17.5-Mesenchymal-mesenchymal_fibroblast|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MME NEBL TSHZ2 ZEB2

5.17e-05194474f15e81ff12525523c62d13105cf264ea72205e2e
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MME NEBL TSHZ2 ZEB2

5.17e-05194474a3e5a15cf6c1361207f661ee15eb634f77daf1cb
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 DDR1 EIF5AL1 DENND2C

5.27e-0519547424d226f89dd337c22728688e4b40ca082a0e1fe1
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MME NEBL TSHZ2 ZEB2

5.27e-05195474598b69032a8441a23749b27863d80f7a1fc82a96
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

LRP4 MUC16 MME NEBL

5.27e-05195474d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

LRP4 MUC16 MME NEBL

5.27e-0519547419853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MME NEBL TSHZ2 ZEB2

5.27e-051954748aa753934debffe5ae4b5eecb6b50c46d17cc3ec
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MME NEBL TSHZ2 ZEB2

5.38e-05196474db64ab27374f82553ee577aec056141170f3656f
ToppCelldistal-3-Epithelial-Differentiating_Basal|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ZNF711 DDR1 B4GALNT4 PRDM16

5.38e-0519647477635a0f86910c4019d3370e9c8ba41de176bcf3
ToppCellcellseq-Epithelial-Epithelial_Airway|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MUC16 DDR1 TSHZ2 DENND2C

5.38e-05196474faa39c567f24403e511b240c1d1a654ffadd8473
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MME NEBL TSHZ2 ZEB2

5.38e-05196474617103f4a09e009fe96c28eb5e40505a4fd6dcf4
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

MME NEBL TSHZ2 ZEB2

5.38e-0519647422538376a95fe3afe8639a216a5497087aa94110
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 DDR1 EIF5AL1 TSHZ2

5.60e-051984743cc9e671f596ef0829684018e4257571fefb6267
ToppCellcellseq-Epithelial-Epithelial_Airway-Basal/Suprabasal-Suprabasal|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MUC16 DDR1 TSHZ2 DENND2C

5.60e-051984746e047de63ef59dcb47e4fc06b173b2a02fdcf4c9
ToppCellBronchial-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Duct|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ZNF711 MUC16 TRPV6 TSHZ2

5.60e-051984741fe60443c11d34b6d2671af8f06e0dedc8d1558b
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 DDR1 NEBL TSHZ2

5.60e-05198474d0ecace1fad24ce50b0935036fabb07e6c9e372d
ToppCellNS-critical-d_07-13|critical / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MUC16 DDR1 NEBL DENND2C

5.60e-05198474a6e11c87b31beffb6af190c64b4ef3ee1d9dab8d
ToppCellNS-moderate-d_16-33-Epithelial|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MUC16 DDR1 NEBL TSHZ2

5.71e-05199474aa2b51940115c22768c0d7493b4b60d41df3f376
ToppCellSepsis-ICU-SEP-Lymphocyte-T/NK-MAIT|ICU-SEP / Disease, condition lineage and cell class

SCLY DUSP10 ACACB PIP4K2A

5.71e-051994742f10622319c6146dfed8cfe3844180c1e1d56e94
ToppCellcontrol-Epithelial|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

MUC16 DDR1 NEBL TSHZ2

5.82e-05200474f95bbb94e51ac28b1995026c599ec3a34e012916
ToppCellcontrol|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DDR1 NEBL TSHZ2 DENND2C

5.82e-0520047497f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCellNS-moderate-d_0-4-Epithelial|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MUC16 DDR1 NEBL TSHZ2

5.82e-0520047464462a18afca3c1a8548a857924b8166058bf958
ToppCellNS-control-d_0-4-Epithelial|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MUC16 DDR1 NEBL TSHZ2

5.82e-05200474d014959891893b6d3854a471fba1dc50c6625a0a
ToppCellNasal_Brush-Epithelial|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

MUC16 DDR1 NEBL TSHZ2

5.82e-052004747911073119ee47a37b68b73fc54f063e902a5067
ToppCellBronchus_Control_(B.)-Epithelial-TX|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

MUC16 DDR1 NEBL TSHZ2

5.82e-05200474f5bc7d30aa03dd0f95eb64255bd1a2543be8d327
ToppCellControl-Epithelial_alveolar-AT_1-Differentiating_AT2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MME PCNX4 DENND2C

4.15e-04138473611fe0fb284e12678f9c47a0bdbfc367a93c52b3
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

NEBL TSHZ2 ZEB2

4.70e-041444731c001a5a3bbe4ecbce8305f8b260e933033550dd
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC8A1 PRDM16 PCNX4

5.29e-0415047387968ce885a4959616f0321f58517fe8029ba1b1
ToppCell3'_v3-Lung-Lymphocytic_T_CD4-Tnaive/CM_CD4_activated|Lung / Manually curated celltypes from each tissue

SCLY TSHZ2 ZNF569

5.39e-041514739bfb807e1180b31fa9a2c500ce993de9707c070f
ToppCellControl-PLT_4|World / Disease Group and Platelet Clusters

ZNF778 ZNF433 DENND2C

5.71e-04154473a2a03c5e6759c45aeeedf1e68ecb5a0112ef9a20
ToppCell10x5'-bone_marrow-Lymphocytic_B-Pro-B|bone_marrow / Manually curated celltypes from each tissue

DDR1 MME MYB

5.71e-041544738a8c3851888ab86ca2b13ccc042cde1fef8d88f8
ToppCellE15.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SLC8A1 NEBL TSHZ2

5.71e-04154473e65e4636646164610f33f7bbac0d879a3ea55986
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EIF5A2 HFM1 ZNF865

5.93e-04156473895927228c93cd090303984c5be6ebfb59ed6f3a
ToppCellsevere-CD4+_T_naive|World / disease stage, cell group and cell class

TSHZ2 ZNF197 MYB

6.04e-04157473ccf9abe0b59e9ea728cec4bba1872ffe14c7385c
ToppCellCOVID_non-vent-Myeloid-Monocytic-SC_&_Eosinophil|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

ZNF711 HFM1 MYB

6.15e-041584730d4fe87fc7901dd5f9c004e91708a03cafdb4ad9
ToppCellLPS-IL1RA-Stromal_mesenchymal-Fibroblasts-MatrixFB_->_Myofibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EIF5A2 HFM1 STAT6

6.38e-04160473778faada072e3abfa76a9a06fd4885fb63de7902
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

EIF5A2 DUSP10 TSHZ2

6.61e-0416247368c40d12689cc1b6c797e6e48173f0110f8144e4
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

EIF5A2 DUSP10 TSHZ2

6.61e-04162473735fa3f77b31a4189e431d05c326403c18cbbffb
ToppCell356C-Myeloid-Dendritic-pDC|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

ZNF711 SGSM1 MYB

6.85e-04164473fed26f4ac36a2b0722bc7b9f91659c5e0cf4d53a
ToppCellE18.5-samps-Mesenchymal-Matrix_fibroblast-MatrixFB-A|E18.5-samps / Age Group, Lineage, Cell class and subclass

MME NEBL ZEB2

6.85e-04164473519ab4fe885dfe4c50846f346a062acc2cb44299
ToppCellT_cells-TFH-like_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

NEBL TSHZ2 MYB

6.85e-04164473b10cf59f4cc37ca6cd0ecf71d7de278cc2bdd8b5
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

EIF5AL1 ZEB2 AGTR1

6.98e-04165473cd8de98af8a1a8a6c81d71fae807cc07f319f4c9
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

EIF5AL1 ZEB2 AGTR1

6.98e-041654734f83ac71efc57be3668d8db1e62bad05dc6a5e2b
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Dendritic-conventional_dendritic_cell-DC_c1-CLEC9A|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZNF322 ERI1 PRDM16

7.10e-04166473c8fd241088de27c6e741a5dfee3cd770183b6bcb
ToppCell10x5'-Liver-Lymphocytic_T_CD4-Tnaive/CM_CD4_activated|Liver / Manually curated celltypes from each tissue

TSHZ2 DENND2C MYB

7.10e-041664739afa33b5ad27dc33576be592f9b22d8161366838
ToppCell367C-Myeloid-Macrophage-FABP4+_Macrophage_3|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

NEBL TSHZ2 AGTR1

7.22e-041674735c82d801e3b7d7c6c967a73b94b2ee2a8da1fd6e
ToppCellPosterior_cortex-Neuronal-Inhibitory|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

DUSP10 MME ZEB2

7.22e-041674739a84f45345c75f2c8ff38a04245aadee2a26a240
ToppCell368C-Fibroblasts-Fibroblast-C_(Myofibroblast)|368C / Donor, Lineage, Cell class and subclass (all cells)

NEBL ZNF197 AGTR1

7.35e-041684731bc6a1915d48f547385ed4f44e118bcc8a4a7b6c
ToppCell368C-Fibroblasts-Fibroblast-C_(Myofibroblast)-|368C / Donor, Lineage, Cell class and subclass (all cells)

NEBL ZNF197 AGTR1

7.35e-0416847369f534de0f9a293047bea03cb1b78551087a8df5
ToppCellControl-Epithelial_alveolar-Mes-like-AT1_Progenitor|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZNF711 MME IDNK

7.35e-0416847349180994311b3f4f9ec338b1d35d8edd7422e3c9
ToppCellControl-Epithelial_alveolar-Mes-like|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZNF711 MME IDNK

7.35e-041684733c2ce9cfaca8ceab9b29f918ab46afc69eba3330
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_ETV4|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PLCZ1 MME TSHZ2

7.48e-04169473716e9d4c5fb99c56b76afaa5ed90bfa859fde802
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

EIF5A2 POLE ZNF197

7.48e-04169473c6e5b179461996ced6c7621dc01cec00d401f4e8
ToppCellMild_COVID-19-Myeloid-MoAM5|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）

DDR1 ZNF433 DENND2C

7.61e-04170473b2daf46ab5a49590ede8f75e4240bfe6e9d8b764
ToppCellfacs-Large_Intestine-Proximal-18m-Epithelial-enterocyte_of_epithelium_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC8A1 C11orf54 IDNK

7.61e-0417047375b0486620cab838d3feb1c3aa965b487a906618
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRP4 NEBL TSHZ2

7.74e-04171473effcc4b6d26eafc2ca6fa08b6fee2689eff48f0f
ToppCellfacs-Lung-Endomucin-3m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SGSM1 TSHZ2 ZEB2

7.87e-04172473b3c4adccc34bb9e4e78e40f4e2e23736c347cc75
ToppCell3'-Distal_airway-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZNF711 ZNF398 FNIP1

7.87e-0417247380b565f6e37f38629f4cf89d5b053b3b8517244e
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TSHZ2 ZEB2 AGTR1

7.87e-041724731ef243bce63d841c25e4b74d029d1377f84bcc3d
ToppCellfacs-Lung-Endomucin-3m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SGSM1 TSHZ2 ZEB2

7.87e-041724732f1673fcb2356684d60871debb0f159aec553a1c
ToppCellmetastatic_Brain-Fibroblasts-Undetermined|Fibroblasts / Location, Cell class and cell subclass

EIF5A SPG11 SCLY

7.87e-04172473c3822ff7329c3ac38c68c5c38cd67c390682e2a6
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TSHZ2 ZEB2 AGTR1

7.87e-04172473ab1c81be29f93ca8920c6ab5ab92f497a9256d3f
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MUC16 SLC8A1 ZEB2

7.87e-0417247372fbfa890995e47048b47199c170cc7dcd7661f8
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MUC16 SLC8A1 ZEB2

7.87e-041724732ca6f0d1181aabe0d0e3e8f2e193f08dbda42dea
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC8A1 ZEB2 MYB

7.87e-04172473f6b4754a7e4b3e38030316a0ae00d932bfa87e41
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC8A1 SGSM1 ACACB

8.00e-041734734bc6d93716f093b460c8b047199db8cab5fea720
ToppCell390C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

ZNF778 ZNF569 ZEB2

8.00e-04173473b9dee61973559e8c2fef3f2dafd43475b386befb
ToppCelldroplet-Fat-Scat-21m-Endothelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NEBL PRDM16 DENND2C

8.00e-04173473f13124b4cf2ac1dc2895f90f5487d6ac681b0ba4
ToppCellCOVID-19-Myeloid-MoAM5,_CCL3L1|COVID-19 / Condition, Lineage and Cell class

FNIP1 DUSP10 ZEB2

8.00e-04173473502f888b7684ed39f5c577eedcacf673ae81d39e
ToppCellwk_15-18-Mesenchymal-Fibroblast-Mesenchymal_3|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ZNF778 HFM1 B4GALNT4

8.00e-04173473b43817a6b1ed8d6b5366702343be4311c0d52d83
ToppCellfacs-Pancreas-Exocrine-18m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP4 ACACB AGTR1

8.13e-04174473165e14cad57e90aa247dcecfaa3c2e8ff2a470ad
ToppCellfacs-Pancreas-Exocrine-18m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP4 ACACB AGTR1

8.13e-041744734289dfc7613db4bb3d706b9b65d06e84c0c53558
ToppCellASK428-Immune-B_cell|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

MUC16 ZNF569 PRDM16

8.13e-04174473b5a7a612a515736cf3489afd0f6ad2054d54526f
DiseaseMuckle-Wells Syndrome

MME ZEB2

2.37e-055462C0268390
Diseaseglucose measurement

EIF5A2 SLC8A1 SGSM1 TSHZ2 PRDM16 DENND2C

2.66e-05380466EFO_0004468
Diseasealkaline phosphatase measurement

EIF5A EIF5AL1 HFM1 ZNF800 B4GALNT4 ERI1 ACACB PIP4K2A

1.56e-041015468EFO_0004533
Diseasepentachlorophenol measurement

MUC16 TSHZ2 PIP4K2A

2.04e-0473463EFO_0022071
Diseaseparathion measurement

MUC16 TSHZ2 PIP4K2A

2.04e-0473463EFO_0022070
Diseasepotassium chromate measurement

MUC16 TSHZ2 PIP4K2A

2.04e-0473463EFO_0022072
Diseasemercuric chloride measurement

MUC16 TSHZ2 PIP4K2A

2.04e-0473463EFO_0022068
Diseaseheptachlor epoxide measurement

MUC16 TSHZ2 PIP4K2A

2.04e-0473463EFO_0022067
Diseasemethoxychlor measurement

MUC16 TSHZ2 PIP4K2A

2.04e-0473463EFO_0022069
Disease4,6-dinitro-o-cresol measurement

MUC16 TSHZ2 PIP4K2A

2.04e-0473463EFO_0022053
Disease2,4,5-trichlorophenol measurement

MUC16 TSHZ2 PIP4K2A

2.04e-0473463EFO_0022052
Diseaseazinphos methyl measurement

MUC16 TSHZ2 PIP4K2A

2.04e-0473463EFO_0022055
Diseasealdrin measurement

MUC16 TSHZ2 PIP4K2A

2.04e-0473463EFO_0022054
Diseasedicofol measurement

MUC16 TSHZ2 PIP4K2A

2.04e-0473463EFO_0022060
Diseasedisulfoton measurement

MUC16 TSHZ2 PIP4K2A

2.04e-0473463EFO_0022062
Diseasedieldrin measurement

MUC16 TSHZ2 PIP4K2A

2.04e-0473463EFO_0022061
Diseaseendrin measurement

MUC16 TSHZ2 PIP4K2A

2.04e-0473463EFO_0022064
Diseaseendosulfan measurement

MUC16 TSHZ2 PIP4K2A

2.04e-0473463EFO_0022063
Diseaseheptachlor measurement

MUC16 TSHZ2 PIP4K2A

2.04e-0473463EFO_0022066
Diseaseethion measurement

MUC16 TSHZ2 PIP4K2A

2.04e-0473463EFO_0022065
Diseasechlorpyrifos measurement

MUC16 TSHZ2 PIP4K2A

2.04e-0473463EFO_0022057
Diseasecadmium chloride measurement

MUC16 TSHZ2 PIP4K2A

2.04e-0473463EFO_0022056
Diseasediazinon measurement

MUC16 TSHZ2 PIP4K2A

2.04e-0473463EFO_0022059
Diseasedibutyl phthalate measurement

MUC16 TSHZ2 PIP4K2A

2.04e-0473463EFO_0022058
Diseaseenvironmental exposure measurement

MUC16 TSHZ2 PIP4K2A

2.04e-0473463EFO_0008360
DiseaseDDT metabolite measurement

MUC16 TSHZ2 PIP4K2A

2.13e-0474463EFO_0007886
Diseasehormone measurement

SLC8A1 TMEM132D MYB

3.09e-0484463EFO_0004730
Diseaseblood cobalt measurement

MUC16 TSHZ2 PIP4K2A

5.31e-04101463EFO_0007577
Diseasebasophil count, eosinophil count

ZNF398 FNIP1 MYB STAT6

5.41e-04241464EFO_0004842, EFO_0005090
Diseaselymphocyte percentage of leukocytes

ZNF778 ZNF800 SLC8A1 PRDM16 PIP4K2A MYB

5.57e-04665466EFO_0007993
Diseasecongestive heart failure (biomarker_via_orthology)

DDR1 SLC8A1 MME

6.28e-04107463DOID:6000 (biomarker_via_orthology)
Diseaseinflammatory biomarker measurement

SLC8A1 DUSP10

7.55e-0426462EFO_0004872
Diseaseblood nickel measurement

MUC16 TSHZ2 PIP4K2A

8.76e-04120463EFO_0007583
DiseaseQRS duration

DDR1 SLC8A1 NEBL PRDM16

1.19e-03298464EFO_0005055
Diseasecoronary aneurysm

NEBL TSHZ2

1.37e-0335462EFO_1000881
Diseaseasthma (implicated_via_orthology)

AGTR1 STAT6

1.37e-0335462DOID:2841 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
MDYDGRPHCGLDDSK

ERI1

286

Q8IV48
DDCPKAGRHNYIFVM

AGTR1

16

P30556
DMKGHFDPAKCRYAL

DDR1

21

Q08345
IDMYGHQFCPENLKK

ACACB

1251

O00763
KYEEDMHRPGSRKFN

MUC16

12556

Q8WXI7
KYEEDMHCPGSRKFN

MUC16

12711

Q8WXI7
GKKYEDICPSTHNMD

EIF5A2

66

Q9GZV4
DCRPFMEYNKSHIQG

DUSP10

176

Q9Y6W6
YCSKRPGMKENVHNT

PCNX4

771

Q63HM2
EAFHCRKNSYMNPEK

MME

731

P08473
GKKYEDICPSTHNMD

EIF5A

66

P63241
MCDHDYDGLLPKSGK

MYB

21

P10242
KDSQGEYKAPQCIHM

POLE

391

Q07864
HDGKGDMRKCPFYAA

HMOX2

256

P30519
CKKEVDFSMYHPDDE

HFM1

1406

A2PYH4
GKKYEDICPSTHNMD

EIF5AL1

66

Q6IS14
DDYHPEENRRKMGKG

IDNK

36

Q5T6J7
PTDAKYHMQRCIDSG

CDC37

326

Q16543
PEKNHLCYRFMKEFT

FNIP1

426

Q8TF40
FPGKDDHGYKQSKDM

DENND2C

516

Q68D51
HYGAQCDKPNKEFML

NDUFA8

31

P51970
IKCHENSPRKEVYFM

PIP4K2A

341

P48426
EDDDSGHCKMNRYDK

ODF2

111

Q5BJF6
DPGDCKELHNYMERL

TMEM132D

1081

Q14C87
FKNECRKVYQDMTHP

PLCZ1

146

Q86YW0
HECKDCERMFPNKYS

PRDM16

281

Q9HAZ2
HMETDNKCFYRESPL

B4GALNT4

381

Q76KP1
TCMRETLEKHYGNKP

C11orf54

186

Q9H0W9
YIKRCRPGDSEKHNM

SPG11

2206

Q96JI7
GCGKHNSPERKVYMD

SCLY

21

Q96I15
HERSHMGEKPYQCKE

ZNF700

296

Q9H0M5
QRMHTGEKPYECDKC

ZNF197

921

O14709
SHKEVHMAEKPYGCD

ZNF865

686

P0CJ78
MRTHTGEKPYECKDC

ZNF778

496

Q96MU6
KDEAFRSHYKPEQMG

STAT6

621

P42226
YPCTDCSKSFMRKEH

ZNF398

511

Q8TD17
CERTHTGEKPYKCDM

ZNF322

61

Q6U7Q0
KYEDCKVHQRGAMGE

TRPV6

106

Q9H1D0
GPCALEYTKMKTADH

SGSM1

176

Q2NKQ1
LKNMDKGHPIFYCSD

TSHZ2

916

Q9NRE2
MRSHTGEKPYECKEC

ZNF569

401

Q5MCW4
THKKFYCPPSLQMDD

ZNF800

86

Q2TB10
LKGYHMKDPCSQPEE

ZEB2

486

O60315
PDHLMRKKYQCTDCD

ZNF711

406

Q9Y462
MHREEKPYECKGYGK

ZNF433

471

Q8N7K0
MYNQLCYKKEGGPDH

LRP4

1786

O75096
GEEKLPSCFDYVMHF

SLC8A1

766

P32418
DAAKGFSDYAHMKEP

NEBL

131

O76041