Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	DUF3534	PARD3B PARD3	6.47e-06	2	48	2	PF12053
Domain	DUF3534	PARD3B PARD3	6.47e-06	2	48	2	IPR021922
Domain	Znf_FYVE_PHD	KDM3A DPF3 PHRF1 DIDO1 BSN	3.68e-05	147	48	5	IPR011011
Domain	PHD	DPF3 PHRF1 DIDO1	9.45e-04	75	48	3	PF00628
Domain	Znf_PHD-finger	DPF3 PHRF1 DIDO1	1.10e-03	79	48	3	IPR019787
Domain	PHD	DPF3 PHRF1 DIDO1	1.55e-03	89	48	3	SM00249
Domain	Znf_PHD	DPF3 PHRF1 DIDO1	1.65e-03	91	48	3	IPR001965
Domain	Chromo_domain	CBX7 CHD9	1.72e-03	24	48	2	IPR023780
Domain	ZF_PHD_2	DPF3 PHRF1 DIDO1	1.87e-03	95	48	3	PS50016
Domain	ZF_PHD_1	DPF3 PHRF1 DIDO1	1.92e-03	96	48	3	PS01359
Domain	Chromo	CBX7 CHD9	2.02e-03	26	48	2	PF00385
Domain	CHROMO_2	CBX7 CHD9	2.34e-03	28	48	2	PS50013
Domain	CHROMO_1	CBX7 CHD9	2.34e-03	28	48	2	PS00598
Domain	Chromodomain-like	CBX7 CHD9	3.05e-03	32	48	2	IPR016197
Domain	-	PLEKHH1 NUMB PLEKHA2 AGAP1 TECPR1	3.20e-03	391	48	5	2.30.29.30
Domain	CHROMO	CBX7 CHD9	3.25e-03	33	48	2	SM00298
Domain	Chromo/shadow_dom	CBX7 CHD9	3.25e-03	33	48	2	IPR000953
Domain	PH_dom-like	PLEKHH1 NUMB PLEKHA2 AGAP1 TECPR1	4.61e-03	426	48	5	IPR011993
Domain	PH	PLEKHH1 PLEKHA2 AGAP1 TECPR1	5.59e-03	278	48	4	SM00233
Domain	PH_DOMAIN	PLEKHH1 PLEKHA2 AGAP1 TECPR1	5.66e-03	279	48	4	PS50003
Domain	PH_domain	PLEKHH1 PLEKHA2 AGAP1 TECPR1	5.73e-03	280	48	4	IPR001849
Domain	-	DPF3 PHRF1 DIDO1 BSN UBOX5	5.75e-03	449	48	5	3.30.40.10
Domain	Znf_RING/FYVE/PHD	DPF3 PHRF1 DIDO1 BSN UBOX5	6.30e-03	459	48	5	IPR013083
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	TANC2 NCOR2 ATN1 DPF3 PRSS56 PHRF1 HELZ CHD9 TIGD5 CRYBG3 PARD3 SPATC1L ZNF646	9.12e-09	1116	53	13	31753913
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	KDM3A PHRF1 NCAPD2 AUTS2 DIDO1 BSN AGAP1 ZNF646	1.32e-06	529	53	8	14621295
Pubmed	Numb controls integrin endocytosis for directional cell migration with aPKC and PAR-3.	NUMB PARD3	2.28e-06	2	53	2	17609107
Pubmed	Association of KIR2DL5B gene with celiac disease supports the susceptibility locus on 19q13.4.	KIR2DL5B KIR2DL5A	2.28e-06	2	53	2	17215859
Pubmed	Some human KIR haplotypes contain two KIR2DL5 genes: KIR2DL5A and KIR2DL5B.	KIR2DL5B KIR2DL5A	2.28e-06	2	53	2	12185535
Pubmed	Gene structure and promoter variation of expressed and nonexpressed variants of the KIR2DL5 gene.	KIR2DL5B KIR2DL5A	2.28e-06	2	53	2	11086080
Pubmed	Par-3 family proteins in cell polarity & adhesion.	PARD3B PARD3	2.28e-06	2	53	2	33565714
Pubmed	Numb regulates vesicular docking for homotypic fusion of early endosomes via membrane recruitment of Mon1b.	NUMB MON1B	2.28e-06	2	53	2	26987402
Pubmed	Gli3 is required for the specification and differentiation of preplate neurons.	NUMB PARD3 AXIN2	3.18e-06	19	53	3	16168404
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	TANC2 ESYT2 MEGF8 NUMB PLEKHA2 HELZ PARD3B CRYBG3 PARD3	5.60e-06	861	53	9	36931259
Pubmed	Scaffold polarity proteins Par3A and Par3B share redundant functions while Par3B acts independent of atypical protein kinase C/Par6 in podocytes to maintain the kidney filtration barrier.	PARD3B PARD3	6.83e-06	3	53	2	34929254
Pubmed	Promoter variants of KIR2DL5 add to diversity and may impact gene expression.	KIR2DL5B KIR2DL5A	6.83e-06	3	53	2	18461314
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	AREL1 ZNF142 CHD9 TECPR1	9.74e-06	87	53	4	12465718
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	PLEKHH1 NCOR2 ESYT2 AUTS2 NUMB PLEKHA2 CHD9 PARD3B PARD3 MCTP2 AGAP1	1.24e-05	1489	53	11	28611215
Pubmed	Killer-cell immunoglobulin-like receptors (KIR) in severe A (H1N1) 2009 influenza infections.	KIR2DL5B KIR2DL5A	1.36e-05	4	53	2	22652695
Pubmed	KIR2DL5, a novel killer-cell receptor with a D0-D2 configuration of Ig-like domains.	KIR2DL5B KIR2DL5A	1.36e-05	4	53	2	10820258
Pubmed	Multiple splice variants of Par3 and of a novel related gene, Par3L, produce proteins with different binding properties.	PARD3B PARD3	1.36e-05	4	53	2	12234671
Pubmed	Investigation of killer cell immunoglobulin-like receptor (KIR) gene diversity: KIR2DL2, KIR2DL5 and KIR2DS5.	KIR2DL5B KIR2DL5A	1.36e-05	4	53	2	18498296
Pubmed	PAR3 restricts the expansion of neural precursor cells by regulating hedgehog signaling.	NUMB PARD3 AXIN2	1.77e-05	33	53	3	36218069
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	AREL1 DIDO1 CHD9 ZNF646	1.97e-05	104	53	4	9205841
Pubmed	Loss of Usp9x disrupts cell adhesion, and components of the Wnt and Notch signaling pathways in neural progenitors.	NUMB PARD3 AXIN2	2.11e-05	35	53	3	28808228
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	KDM3A NCOR2 ESYT2 ATN1 PHRF1 DIDO1 HELZ PARD3	2.12e-05	774	53	8	15302935
Pubmed	Two forms of human Inscuteable-related protein that links Par3 to the Pins homologues LGN and AGS3.	PARD3B PARD3	3.40e-05	6	53	2	16458856
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	ESYT2 NUMB PLEKHA2 PARD3B PARD3 AGAP1	4.31e-05	421	53	6	36976175
Pubmed	Histone deacetylase-associating Atrophin proteins are nuclear receptor corepressors.	NCOR2 ATN1	4.76e-05	7	53	2	16481466
Pubmed	PAR3beta, a novel homologue of the cell polarity protein PAR3, localizes to tight junctions.	PARD3B PARD3	4.76e-05	7	53	2	12459187
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	NCOR2 ATN1 NUMB TEX14 BSN TECPR1	4.85e-05	430	53	6	35044719
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	TANC2 PLEKHH1 NCOR2 ZNF142 MEGF8 TIGD5 BSN	5.02e-05	638	53	7	31182584
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	CDCA3 NUMB HELZ CRYBG3 PARD3	5.08e-05	263	53	5	34702444
Pubmed	Left-right function of dmrt2 genes is not conserved between zebrafish and mouse.	DMRT2 AXIN2	6.34e-05	8	53	2	21203428
Pubmed	Genetic utility of broadly defined bipolar schizoaffective disorder as a diagnostic concept.	AUTS2 BSN	6.34e-05	8	53	2	19567891
Pubmed	Cell polarity and spindle orientation in the distal epithelium of embryonic lung.	NUMB PARD3	1.02e-04	10	53	2	21246661
Pubmed	Notch Activation by Shootin1 Opposing Activities on 2 Ubiquitin Ligases.	NUMB PARD3	1.24e-04	11	53	2	28981589
Pubmed	Different KIRs confer susceptibility and protection to adults with latent autoimmune diabetes in Latvian and Asian Indian populations.	KIR2DL5B KIR2DL5A	1.76e-04	13	53	2	19120281
Pubmed	A gene-rich cluster between the CD4 and triosephosphate isomerase genes at human chromosome 12p13.	CDCA3 ATN1	2.05e-04	14	53	2	8723724
Pubmed	Epicardial spindle orientation controls cell entry into the myocardium.	NUMB PARD3	2.05e-04	14	53	2	20643355
Pubmed	Comparative sequence analysis of a gene-rich cluster at human chromosome 12p13 and its syntenic region in mouse chromosome 6.	CDCA3 ATN1	2.70e-04	16	53	2	9445485
Pubmed	[Polymorphism of killer cell immunoglobulin-like receptors gene family in Zhejiang Han population].	KIR2DL5B KIR2DL5A	2.70e-04	16	53	2	16403292
Pubmed	Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.	CDCA3 ESYT2 NUMB PARD3B AGAP1	2.73e-04	377	53	5	38117590
Pubmed	[Analysis of natural killer cell immunoglobulin-like receptor genes in Chinese].	KIR2DL5B KIR2DL5A	3.05e-04	17	53	2	19218127
Pubmed	Association of KIR2DS1 and KIR2DS3 with fatal outcome in Ebola virus infection.	KIR2DL5B KIR2DL5A	3.05e-04	17	53	2	20878400
Pubmed	Killer cell immunoglobulin-like receptor gene diversity in the Tibetan ethnic minority group of China.	KIR2DL5B KIR2DL5A	3.05e-04	17	53	2	20650299
Pubmed	Killer cell immunoglobulin-like receptor gene polymorphisms in patients with leukemia: possible association with susceptibility to the disease.	KIR2DL5B KIR2DL5A	3.05e-04	17	53	2	19450876
Pubmed	Numb is required for the production of terminal asymmetric cell divisions in the developing mouse retina.	NUMB PARD3	3.05e-04	17	53	2	23197712
Pubmed	Distribution of killer-cell immunoglobulin-like receptor genes in Eastern mainland Chinese Han and Taiwanese Han populations.	KIR2DL5B KIR2DL5A	3.05e-04	17	53	2	19761533
Pubmed	Signatures of natural selection and coevolution between killer cell immunoglobulin-like receptors (KIR) and HLA class I genes.	KIR2DL5B KIR2DL5A	3.43e-04	18	53	2	20200544
Pubmed	αE-catenin inhibits YAP/TAZ activity to regulate signalling centre formation during tooth development.	PARD3 AXIN2	3.83e-04	19	53	2	27405641
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	ESYT2 PHRF1 NCAPD2 SLC35E1 NUMB DIDO1 HELZ PARD3 AGAP1	3.96e-04	1497	53	9	31527615
Pubmed	Large-scale sequencing in human chromosome 12p13: experimental and computational gene structure determination.	CDCA3 ATN1	4.25e-04	20	53	2	9074930
Pubmed	HLA and KIR frequencies in Sicilian Centenarians.	KIR2DL5B KIR2DL5A	4.25e-04	20	53	2	20426625
Pubmed	Compound KIR-HLA genotype analyses in the Iranian population by a novel PCR-SSP assay.	KIR2DL5B KIR2DL5A	4.25e-04	20	53	2	20193031
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	NCOR2 ESYT2 ZNF142 ATN1 NCAPD2 SLC35E1 AUTS2 ZNF646	4.45e-04	1203	53	8	29180619
Pubmed	SNAP23 deficiency causes severe brain dysplasia through the loss of radial glial cell polarity.	PARD3 AXIN2	4.70e-04	21	53	2	33332551
Pubmed	DIAPH3 deficiency links microtubules to mitotic errors, defective neurogenesis, and brain dysfunction.	NUMB PARD3	5.16e-04	22	53	2	33899739
Pubmed	The transition from radial glial to intermediate progenitor cell is inhibited by FGF signaling during corticogenesis.	NUMB PARD3	5.16e-04	22	53	2	19923290
Pubmed	Distribution of KIR genes in the population of unrelated individuals homozygous for ancestral haplotype AH8.1 (HLA-A1B8DR3).	KIR2DL5B KIR2DL5A	5.16e-04	22	53	2	20492596
Pubmed	Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.	NCOR2 ATN1 RBM12B AUTS2 HELZ	6.55e-04	457	53	5	32344865
Pubmed	Nubp1 is required for lung branching morphogenesis and distal progenitor cell survival in mice.	NUMB PARD3	6.68e-04	25	53	2	23028652
Pubmed	Interaction proteomics analysis of polycomb proteins defines distinct PRC1 complexes in mammalian cells.	KDM3A NCOR2 CBX7	7.50e-04	116	53	3	21282530
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	STARD13 TANC2 FAM210A SLC35E1 NUMB HELZ PARD3 AGAP1	8.22e-04	1321	53	8	27173435
Pubmed	Osteocyte transcriptome mapping identifies a molecular landscape controlling skeletal homeostasis and susceptibility to skeletal disease.	STARD13 AUTS2	8.40e-04	28	53	2	33953184
Pubmed	Secreted frizzled-related proteins are required for Wnt/β-catenin signalling activation in the vertebrate optic cup.	PARD3 AXIN2	8.40e-04	28	53	2	21896628
Pubmed	KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4.	KDM3A NCOR2 DIDO1	1.04e-03	130	53	3	35545047
Pubmed	Association of mitotic regulation pathway polymorphisms with pancreatic cancer risk and outcome.	TEX14 AXIN2	1.10e-03	32	53	2	20056645
Pubmed	ESYT1 tethers the ER to mitochondria and is required for mitochondrial lipid and calcium homeostasis.	CDCA3 KDM3A ESYT2 NUMB	1.13e-03	299	53	4	37931956
Pubmed	α-catenin interaction with YAP/FoxM1/TEAD-induced CEP55 supports liver cancer cell migration.	NUMB PARD3	1.31e-03	35	53	2	37381005
Pubmed	Role of human leukocyte antigen, killer-cell immunoglobulin-like receptors, and cytokine gene polymorphisms in leptospirosis.	KIR2DL5B KIR2DL5A	1.31e-03	35	53	2	19683555
Pubmed	Host PDZ-containing proteins targeted by SARS-CoV-2.	PARD3B PARD3	1.31e-03	35	53	2	33864728
Pubmed	Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.	NCOR2 CBX7 MED13L PARD3 AGAP1	1.33e-03	536	53	5	15840001
Pubmed	Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals.	NCOR2 DIDO1 MON1B	1.34e-03	142	53	3	19851296
Pubmed	Exchangeable gene trap using the Cre/mutated lox system.	NCOR2 CBX7 MED13L PARD3 AGAP1	1.35e-03	538	53	5	10512203
Pubmed	Association of genetic variants with hemorrhagic stroke in Japanese individuals.	NCOR2 DIDO1 MON1B	1.37e-03	143	53	3	20198315
Pubmed	Identification of phagocytosis regulators using magnetic genome-wide CRISPR screens.	NUMB PLEKHA2 CRYBG3	1.37e-03	143	53	3	30397336
Pubmed	Adamts18 Deficiency Causes Spontaneous SMG Fibrogenesis in Adult Mice.	BTBD7 PARD3	1.47e-03	37	53	2	34323105
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	KDM3A NCAPD2 NUMB DIDO1 PARD3	1.48e-03	549	53	5	38280479
Cytoband	Ensembl 112 genes in cytogenetic band chr14q24	PLEKHH1 AREL1 DPF3 NUMB	8.66e-05	200	53	4	chr14q24
GeneFamily	CD molecules\|Killer cell immunoglobulin like receptors	KIR2DL5B KIR2DL5A	4.56e-04	18	32	2	620
GeneFamily	PHD finger proteins	DPF3 PHRF1 DIDO1	5.33e-04	90	32	3	88
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	PLEKHH1 PLEKHA2 AGAP1	5.67e-03	206	32	3	682
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	STARD13 KDM3A NCOR2 NUMB HELZ CHD9 CRYBG3 MED13L PARD3 AGAP1	3.39e-06	856	49	10	M4500
Coexpression	GRYDER_PAX3FOXO1_TOP_ENHANCERS	STARD13 NCOR2 ESYT2 DMRT2 AUTS2 MED13L PARD3	1.70e-05	441	49	7	M172
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN	STARD13 NUMB HELZ CHD9 MED13L PARD3 AGAP1	2.42e-05	466	49	7	M13522
Coexpression	GSE18893_TCONV_VS_TREG_2H_TNF_STIM_DN	TANC2 BTBD7 CBX7 AUTS2 MED13L	3.09e-05	194	49	5	M7306
Coexpression	HALLMARK_WNT_BETA_CATENIN_SIGNALING	NCOR2 NUMB AXIN2	6.70e-05	42	49	3	M5895
CoexpressionAtlas	alpha beta T cells, NKT.4-.Lv, CD45 TCRb aGalCer-loaded CD1d tet, Liver, avg-4	ESYT2 ATN1 CBX7 RINL MCTP2 AXIN2 TECPR1	1.31e-05	351	48	7	GSM538325_500
CoexpressionAtlas	alpha beta T cells, T.8Eff.Sp.OT1.d15.VSVOva, CD8+ CD45.1+, Spleen, avg-2	TANC2 ESYT2 CBX7 RINL MCTP2 AXIN2 TECPR1	1.57e-05	361	48	7	GSM538385_500
CoexpressionAtlas	CD positive, CD4 Test JS, 4+8-B220-, Spleen, avg-3	ESYT2 ATN1 CBX7 RINL AXIN2 TECPR1	1.51e-04	359	48	6	GSM404000_500
CoexpressionAtlas	alpha beta T cells, T.4Mem44h62l.Sp, CD4 TCRb CD44hi CD62Llo, Spleen, avg-3	ESYT2 CBX7 RINL MCTP2 AXIN2 TECPR1	1.51e-04	359	48	6	GSM538371_500
CoexpressionAtlas	alpha beta T cells, T.4FP3-.Sp, 4+ 8- GFP- 44lo, Spleen, avg-3	ESYT2 ATN1 CBX7 RINL AXIN2 TECPR1	1.63e-04	364	48	6	GSM605766_500
CoexpressionAtlas	alpha beta T cells, T.8Mem.Sp.OT1.d106.VSVOva, CD8+ CD45.1+, Spleen, avg-2	ESYT2 CBX7 RINL MCTP2 AXIN2 TECPR1	1.70e-04	367	48	6	GSM538401_500
CoexpressionAtlas	alpha beta T cells, T.8Eff.Sp.OT1.d6.VSVOva, CD8+ CD45.1+, Spleen, avg-3	TANC2 ESYT2 NCAPD2 RINL MCTP2 TECPR1	1.88e-04	374	48	6	GSM538389_500
CoexpressionAtlas	alpha beta T cells, T.8Eff.Sp.OT1.d15.LisOva, CD8+ CD45.1+, Spleen, avg-3	ESYT2 CBX7 RINL MCTP2 AXIN2 TECPR1	1.94e-04	376	48	6	GSM605894_500
CoexpressionAtlas	alpha beta T cells, T.8Mem.Sp.OT1.d45.VSVOva, CD8+ CD45.1+, Spleen, avg-3	ESYT2 CBX7 RINL MCTP2 AXIN2 TECPR1	2.14e-04	383	48	6	GSM538403_500
CoexpressionAtlas	alpha beta T cells, NKT.44+NK1.1+.Th, aGC CD1d tet CD3e CD44 NK1.1, Thymus, avg-3	ATN1 CBX7 RINL MCTP2 AXIN2 TECPR1	2.20e-04	385	48	6	GSM538332_500
CoexpressionAtlas	alpha beta T cells, T.8Eff.Sp.OT1.d8.VSVOva, CD8+ CD45.1+, Spleen, avg-3	ESYT2 CBX7 RINL MCTP2 AXIN2 TECPR1	2.27e-04	387	48	6	GSM538392_500
CoexpressionAtlas	gamma delta T cells, Tgd.vg2+.act.Sp, TCRd+ Vg2+ CD44+, Spleen, avg-3	ESYT2 ATN1 CBX7 RINL AXIN2 TECPR1	2.53e-04	395	48	6	GSM476678_500
ToppCell	Bronchial-NucSeq\|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations	STARD13 TANC2 AUTS2 PARD3B MED13L PARD3 AGAP1	2.63e-09	196	51	7	ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	STARD13 TANC2 AUTS2 PARD3B MED13L PARD3 AGAP1	2.82e-09	198	51	7	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	STARD13 AUTS2 PARD3B MED13L PARD3 AGAP1	1.06e-07	199	51	6	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	TCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma-Intrahepatic\|TCGA-Bile_Duct / Sample_Type by Project: Shred V9	TANC2 NCOR2 ATN1 SLC35E1 PARD3	3.28e-06	200	51	5	1fa8422fd820d21e285a7e7c4c6fbd8b7277d2af
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-5w-Neuronal-Intermediate\|5w / Sample Type, Dataset, Time_group, and Cell type.	TANC2 ATN1 MEGF8 AUTS2 AGAP1	3.28e-06	200	51	5	c92e4fc0442404481fcac623d691dae6215b852d
ToppCell	TCGA-Peripheral_Nervous_System-Primary_Tumor-Paraganglioma-Paraganglioma-3\|TCGA-Peripheral_Nervous_System / Sample_Type by Project: Shred V9	TANC2 RBM12B DIDO1 CHD9	1.74e-05	135	51	4	ac20133d4a36f48338b45bffb13e842cb66f83ad
ToppCell	renal_papilla_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	STARD13 ESYT2 AUTS2 MCTP2	5.35e-05	180	51	4	49829e833fe6d2431cfd2e8f378c2aaa3b2b46a4
ToppCell	343B-Fibroblasts-Fibroblast-E\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	KDM3A NCAPD2 UBOX5 AXIN2	5.95e-05	185	51	4	02cbf492bc40abebaa93a3a208888afae72fbe06
ToppCell	343B-Fibroblasts-Fibroblast-E-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	KDM3A NCAPD2 UBOX5 AXIN2	5.95e-05	185	51	4	1b8e3ddb91797f84e4b15d2457b0c008e5be50db
ToppCell	COPD-Epithelial-ATII\|Epithelial / Disease state, Lineage and Cell class	STARD13 TANC2 AUTS2 TEX14	6.20e-05	187	51	4	030af361f8bdcd0aff4ec1922702833325cf74d8
ToppCell	COPD-Multiplet-Multiplet\|World / Disease state, Lineage and Cell class	AUTS2 PARD3 MCTP2 AGAP1	6.33e-05	188	51	4	186fe1ea328c942910190a4240262c0d8642ea3b
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	STARD13 TANC2 APCDD1L PLEKHA2	6.59e-05	190	51	4	11d3c31167ea71809b4cc3757a0c6ea54a448602
ToppCell	Control-Multiplet-Multiplet\|World / Disease state, Lineage and Cell class	AUTS2 PARD3 MCTP2 AGAP1	6.87e-05	192	51	4	1bfd022d5b87cf8a5d5069f559339a553a52a0a2
ToppCell	Adult-Epithelial\|Adult / Lineage, Cell type, age group and donor	AUTS2 PARD3B PARD3 AGAP1	6.87e-05	192	51	4	efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	PARD3B MED13L PARD3 AGAP1	6.87e-05	192	51	4	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	10x5'-blood-Lymphocytic_NK-NK_CD16\|blood / Manually curated celltypes from each tissue	ESYT2 AUTS2 PLEKHA2 MCTP2	7.15e-05	194	51	4	c34a32f1cfe3e597cb0f91ba5bdd3e114e9f3d2e
ToppCell	10x5'-blood-Lymphocytic_NK\|blood / Manually curated celltypes from each tissue	ESYT2 AUTS2 PLEKHA2 MCTP2	7.29e-05	195	51	4	c1db871e8e8e8b8d6a5798bc43eaf54e102b75eb
ToppCell	LA-02._Fibroblast_II\|World / Chamber and Cluster_Paper	NCOR2 CHD9 PARD3B AGAP1	7.29e-05	195	51	4	a78b605b49acd8c9d68716266ca269dafcd910b9
Drug	irinotecan HCl; Down 200; 100uM; MCF7; HT_HG-U133A	STARD13 TANC2 NUMB CHD9 MED13L PARD3	2.78e-06	174	52	6	7530_DN
Drug	Sulmazole [73384-60-8]; Up 200; 14uM; MCF7; HT_HG-U133A	STS ATN1 PLEKHA2 TEX14 MCTP2 ZNF646	5.52e-06	196	52	6	4127_UP
Disease	developmental disorder of mental health (implicated_via_orthology)	TANC2 NCOR2 PARD3B PARD3	1.35e-06	49	49	4	DOID:0060037 (implicated_via_orthology)
Disease	cholesteryl ester 16:2 measurement	AREL1 DPF3	5.64e-05	7	49	2	EFO_0021435
Disease	body surface area	NCOR2 C12orf42 AUTS2 DIDO1 MED13L PARD3 AXIN2	8.77e-05	643	49	7	EFO_0022196
Disease	hippocampal volume	DIDO1 PARD3B MED13L MCTP2 AXIN2	1.33e-04	297	49	5	EFO_0005035
Disease	hemifacial microsomia	PARD3B AGAP1	4.54e-04	19	49	2	MONDO_0015398
Disease	Neurodevelopmental Disorders	TANC2 PARD3B MED13L	5.03e-04	93	49	3	C1535926
Disease	X-24309 measurement	DPF3 NUMB	5.04e-04	20	49	2	EFO_0800872
Disease	Abnormality of refraction	CDCA3 PRSS56 PHRF1 AUTS2 PARD3 AXIN2	8.36e-04	673	49	6	HP_0000539
Disease	cortical surface area measurement	TANC2 DMRT2 AUTS2 PARD3B MED13L PARD3 MCTP2 AGAP1	1.56e-03	1345	49	8	EFO_0010736
Disease	colorectal carcinoma (is_marker_for)	CBX7 AXIN2	1.73e-03	37	49	2	DOID:0080199 (is_marker_for)
Disease	Parkinson disease, disease progression measurement	PARD3 MCTP2	1.92e-03	39	49	2	EFO_0008336, MONDO_0005180
Disease	ovarian carcinoma	KDM3A AUTS2 PARD3B MON1B	1.98e-03	321	49	4	EFO_0001075
Disease	eye disease	CDCA3 PRSS56	2.56e-03	45	49	2	EFO_0003966
Disease	ocular hypertension, response to triamcinolone acetonide	CHD9 TEX14	3.02e-03	49	49	2	EFO_0006954, EFO_1001069
Disease	abdominal adipose tissue measurement	DMRT2 UBOX5	3.53e-03	53	49	2	EFO_0803316
Disease	alcohol use disorder (implicated_via_orthology)	KDM3A DPF3 AUTS2	4.19e-03	195	49	3	DOID:1574 (implicated_via_orthology)
Disease	Seizures	TANC2 ZNF142 ATN1	5.71e-03	218	49	3	C0036572
Disease	synophrys measurement	DMRT2 AUTS2	5.74e-03	68	49	2	EFO_0007906
Disease	congenital heart disease (implicated_via_orthology)	CHD9 AXIN2	5.90e-03	69	49	2	DOID:1682 (implicated_via_orthology)
Disease	hematocrit	STARD13 NCOR2 DPF3 CBX7 NUMB BSN	6.35e-03	1011	49	6	EFO_0004348
Disease	Intellectual Disability	TANC2 ZNF142 ATN1 MED13L	6.43e-03	447	49	4	C3714756
Disease	coronary artery calcification	CBX7 NUMB MED13L AGAP1	6.58e-03	450	49	4	EFO_0004723

Protein segments in the cluster

Peptide	Gene	Start	Entry
LDAHPPQPGVLRHKQ	FAM210A	71	Q96ND0
ERPPDHQHSAQVKRP	ESYT2	661	A0FGR8
LDPPPSPHANRKKHR	AGAP1	516	Q9UPQ3
PSPNKSIRHEHLQLP	CRYBG3	456	Q68DQ2
NPLLPHPLHENEVLR	ATN1	1101	P54259
DFSRPPQHRPSLQKH	APCDD1L	461	Q8NCL9
QVSLPHFPRTHRLPK	AXIN2	346	Q9Y2T1
PHNKHLARVADPRSP	CDCA3	16	Q99618
KHPQRDFRQPDRHPP	RBM12B	541	Q8IXT5
LPNAKPRSLSPAHKH	KIR2DL5A	331	Q8N109
KPLDIPDHHRQLPQF	MON1B	416	Q7L1V2
EAAHLPHLRPLPESQ	NCOR2	2096	Q9Y618
EVRKNDLPFHRPRPH	PARD3B	756	Q8TEW8
NPSKPPDLRARHHLD	MCTP2	31	Q6DN12
PARNSQRVPHPLDSK	MED13L	2146	Q71F56
RSPPNHRNENHRPQK	DPF3	236	Q92784
AHLHKPRADPQLPSR	MAPK15	366	Q8TD08
QPPIEKEDNGLHPHR	LRRC53	506	A6NM62
SQEPAALPKRRLPHN	BSN	886	Q9UPA5
LPNAKPRSLSPAHKH	KIR2DL5B	331	Q8NHK3
RKEDHDLPPEAPQTH	AUTS2	986	Q8WXX7
SPHLKEPRPRLFHAS	MEGF8	1776	Q7Z7M0
AEDRAPRAPLHRPQK	PHRF1	1416	Q9P1Y6
FPRKDNLNPRHINLP	HELZ	1331	P42694
HPQLFERLKLCHPNP	CHD9	1941	Q3L8U1
LHFPNSPEENLRKRP	FER1L6-AS2	56	Q96M78
ANPPELQKHLEHAPS	KDM3A	431	Q9Y4C1
SKENTRHPLPLRHNP	DMRT2	456	Q9Y5R5
HSHRRELFLQEPPAP	CBX7	166	O95931
LLELPSHPPQHRKDR	DIDO1	2026	Q9BTC0
LVHPNPNRPAHLRLK	AREL1	536	O15033
LSPDGHLHRQKNEPI	BTBD7	1011	Q9P203
RILPHPKFDPRTFHN	PRSS56	176	P0CW18
PRLNHPPEQIDSHSR	PARD3	406	Q8TEW0
NNPHAIPRRHAPIEQ	NUMB	256	P49757
HYKPLARRHLPQSPD	NUTM2D	266	Q5VT03
SRPEHHRPEAKPQRT	NRAC	51	Q8N912
RIRHRSEPQHPKEKP	PLEKHA2	396	Q9HB19
SQPLPHPSLKARIDH	UBOX5	316	O94941
NHPFHPKNEKPTRAR	STARD13	241	Q9Y3M8
IRHPSPRQKEQPEHS	TEX14	1031	Q8IWB6
NSLHSAVPKRHPRLP	TEX53	41	A0A1B0GU33
HHDPPLLFDISKDPR	STS	496	P08842
PHASPKHVDANRELP	TANC2	401	Q9HCD6
HRSPLEKPHNGLLFP	SLC35E1	361	Q96K37
KQRPDLRANPLHSSP	SPATC1L	286	Q9H0A9
GKRHPPFRLPQEHRL	NCAPD2	831	Q15021
PKHPHTPRDRRPQAD	C12orf42	286	Q96LP6
TLHRKDHPRAQANLP	RINL	536	Q6ZS11
LQHRPLDRVALPSPH	TECPR1	101	Q7Z6L1
PELSRHRELLHPSPN	ZNF646	21	O15015
PRDSIQLAKRHHSQP	PLEKHH1	321	Q9ULM0
LKQHALRRHPEPAQP	ZNF142	1301	P52746
RLPDPPSLRHHNQDK	TIGD5	296	Q53EQ6