Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
HumanPheno	Widened distal phalanges	FLNB CREBBP	2.54e-05	4	11	2	HP:0006200
MousePheno	herniated intestine	SHROOM3 SLIT3	2.66e-05	4	30	2	MP:0005155
MousePheno	impaired lectin complement pathway	MASP1 MASP2	2.66e-05	4	30	2	MP:0009062
MousePheno	absent organized vascular network	PAXIP1 CREBBP	1.24e-04	8	30	2	MP:0000263
Domain	Pept_S1A_C1r/C1S/mannan-bd	MASP1 MASP2	2.29e-05	4	37	2	IPR024175
Domain	CTCK_1	MUC19 SLIT3	5.73e-04	18	37	2	PS01185
Domain	CT	MUC19 SLIT3	8.60e-04	22	37	2	SM00041
Domain	EGF_Ca-bd_CS	MASP1 SLIT3 MASP2	9.28e-04	97	37	3	IPR018097
Domain	EGF_CA	MASP1 SLIT3 MASP2	9.85e-04	99	37	3	PS01187
Domain	TRYPSIN_HIS	MASP1 LPA MASP2	1.10e-03	103	37	3	IPR018114
Domain	Cys_knot_C	MUC19 SLIT3	1.11e-03	25	37	2	IPR006207
Domain	CTCK_2	MUC19 SLIT3	1.11e-03	25	37	2	PS01225
Domain	TRYPSIN_SER	MASP1 LPA MASP2	1.20e-03	106	37	3	PS00135
Domain	EGF-type_Asp/Asn_hydroxyl_site	MASP1 SLIT3 MASP2	1.20e-03	106	37	3	IPR000152
Domain	TRYPSIN_HIS	MASP1 LPA MASP2	1.23e-03	107	37	3	PS00134
Domain	EGF-like_dom	LAMB1 MASP1 SLIT3 MASP2	1.44e-03	249	37	4	IPR000742
Domain	Peptidase_S1A	MASP1 LPA MASP2	1.44e-03	113	37	3	IPR001314
Domain	TRYPSIN_DOM	MASP1 LPA MASP2	1.52e-03	115	37	3	PS50240
Domain	EGF_1	LAMB1 MASP1 SLIT3 MASP2	1.57e-03	255	37	4	PS00022
Domain	Tryp_SPc	MASP1 LPA MASP2	1.59e-03	117	37	3	SM00020
Domain	EGF-like_CS	LAMB1 MASP1 SLIT3 MASP2	1.71e-03	261	37	4	IPR013032
Domain	Trypsin	MASP1 LPA MASP2	1.75e-03	121	37	3	PF00089
Domain	Trypsin_dom	MASP1 LPA MASP2	1.75e-03	121	37	3	IPR001254
Domain	EGF_CA	MASP1 SLIT3 MASP2	1.80e-03	122	37	3	SM00179
Domain	EGF_2	LAMB1 MASP1 SLIT3 MASP2	1.81e-03	265	37	4	PS01186
Domain	Peptidase_S1_PA	MASP1 LPA MASP2	1.84e-03	123	37	3	IPR009003
Domain	EGF-like_Ca-bd_dom	MASP1 SLIT3 MASP2	1.88e-03	124	37	3	IPR001881
Domain	BROMODOMAIN_1	CREBBP ASH1L	2.43e-03	37	37	2	PS00633
Domain	Bromodomain	CREBBP ASH1L	2.57e-03	38	37	2	PF00439
Domain	BROMODOMAIN_2	CREBBP ASH1L	2.98e-03	41	37	2	PS50014
Domain	BROMO	CREBBP ASH1L	3.13e-03	42	37	2	SM00297
Domain	Bromodomain	CREBBP ASH1L	3.13e-03	42	37	2	IPR001487
Domain	-	CREBBP ASH1L	3.13e-03	42	37	2	1.20.920.10
Domain	CUB	MASP1 MASP2	4.24e-03	49	37	2	PF00431
Domain	CUB	MASP1 MASP2	4.41e-03	50	37	2	SM00042
Domain	Sushi	MASP1 MASP2	4.76e-03	52	37	2	PF00084
Domain	-	MASP1 MASP2	4.76e-03	52	37	2	2.60.120.290
Domain	CUB	MASP1 MASP2	4.94e-03	53	37	2	PS01180
Domain	CCP	MASP1 MASP2	5.12e-03	54	37	2	SM00032
Domain	KRAB	ZNF778 ZNF45 ZNF689 ZNF780B	5.32e-03	358	37	4	PS50805
Domain	KRAB	ZNF778 ZNF45 ZNF689 ZNF780B	5.32e-03	358	37	4	PF01352
Domain	SUSHI	MASP1 MASP2	5.50e-03	56	37	2	PS50923
Domain	Sushi_SCR_CCP_dom	MASP1 MASP2	5.69e-03	57	37	2	IPR000436
Domain	CUB_dom	MASP1 MASP2	5.69e-03	57	37	2	IPR000859
Domain	KRAB	ZNF778 ZNF45 ZNF689 ZNF780B	5.92e-03	369	37	4	SM00349
Domain	KRAB	ZNF778 ZNF45 ZNF689 ZNF780B	5.98e-03	370	37	4	IPR001909
Pathway	REACTOME_FICOLINS_BIND_TO_REPETITIVE_CARBOHYDRATE_STRUCTURES_ON_THE_TARGET_CELL_SURFACE	MASP1 MASP2	4.07e-05	5	29	2	M27204
Pathway	KEGG_MEDICUS_REFERENCE_REGULATION_OF_FIBRINOLYTIC_SYSTEM_C1INH	MASP1 MASP2	6.10e-05	6	29	2	M47882
Pathway	REACTOME_LECTIN_PATHWAY_OF_COMPLEMENT_ACTIVATION	MASP1 MASP2	8.53e-05	7	29	2	MM14654
Pathway	REACTOME_LECTIN_PATHWAY_OF_COMPLEMENT_ACTIVATION	MASP1 MASP2	1.14e-04	8	29	2	M27005
Pathway	REACTOME_SARS_COV_2_ACTIVATES_MODULATES_INNATE_AND_ADAPTIVE_IMMUNE_RESPONSES	MASP1 NUP214 CREBBP MASP2	1.22e-04	126	29	4	M45009
Pathway	BIOCARTA_LECTIN_PATHWAY	MASP1 MASP2	2.22e-04	11	29	2	MM1430
Pathway	KEGG_MEDICUS_REFERENCE_LECTIN_PATHWAY_OF_COMPLEMENT_CASCADE_C4_C2_TO_C3_CONVERTASE_FORMATION	MASP1 MASP2	2.22e-04	11	29	2	M47874
Pathway	BIOCARTA_LECTIN_PATHWAY	MASP1 MASP2	3.14e-04	13	29	2	M4732
Pathway	BIOCARTA_COMP_PATHWAY	MASP1 MASP2	5.45e-04	17	29	2	MM1369
Pathway	BIOCARTA_COMP_PATHWAY	MASP1 MASP2	7.59e-04	20	29	2	M917
Pathway	REACTOME_SIGNALING_BY_ROBO_RECEPTORS	ABL2 SLIT3	7.59e-04	20	29	2	MM14974
Pathway	REACTOME_SARS_COV_2_HOST_INTERACTIONS	MASP1 NUP214 CREBBP MASP2	7.62e-04	204	29	4	M45011
Pathway	WP_COMPLEMENT_ACTIVATION	MASP1 MASP2	9.20e-04	22	29	2	M39502
Pathway	WP_COMPLEMENT_SYSTEM	LAMB1 MASP1 MASP2	9.84e-04	96	29	3	M39581
Pubmed	Mannose-binding lectin (MBL)-associated serine protease (MASP)-1 contributes to activation of the lectin complement pathway.	MASP1 MASP2	1.10e-06	2	37	2	18424734
Pubmed	Selective inhibition of the lectin pathway of complement with phage display selected peptides against mannose-binding lectin-associated serine protease (MASP)-1 and -2: significant contribution of MASP-1 to lectin pathway activation.	MASP1 MASP2	1.10e-06	2	37	2	20817870
Pubmed	Cutting Edge: Role of MASP-3 in the Physiological Activation of Factor D of the Alternative Complement Pathway.	MASP1 MASP2	1.10e-06	2	37	2	31399515
Pubmed	Dissociation and re-association studies on the interaction domains of mannan-binding lectin (MBL)-associated serine proteases, MASP-1 and MASP-2, provide evidence for heterodimer formation.	MASP1 MASP2	1.10e-06	2	37	2	24424083
Pubmed	Serine proteases of the complement lectin pathway and their genetic variations in ischaemic stroke.	MASP1 MASP2	1.10e-06	2	37	2	28720568
Pubmed	MBL-associated serine proteases (MASPs) and infectious diseases.	MASP1 MASP2	1.10e-06	2	37	2	25862418
Pubmed	Plasma levels of mannan-binding lectin-associated serine proteases MASP-1 and MASP-2 are elevated in type 1 diabetes and correlate with glycaemic control.	MASP1 MASP2	1.10e-06	2	37	2	25533914
Pubmed	The role of MASP-1/3 in complement activation.	MASP1 MASP2	1.10e-06	2	37	2	23402018
Pubmed	Molecular characterization of a novel serine protease involved in activation of the complement system by mannose-binding protein.	MASP1 MASP2	1.10e-06	2	37	2	8018603
Pubmed	The lectin complement pathway serine proteases (MASPs) represent a possible crossroad between the coagulation and complement systems in thromboinflammation.	MASP1 MASP2	1.10e-06	2	37	2	26614707
Pubmed	Monospecific inhibitors show that both mannan-binding lectin-associated serine protease-1 (MASP-1) and -2 Are essential for lectin pathway activation and reveal structural plasticity of MASP-2.	MASP1 MASP2	1.10e-06	2	37	2	22511776
Pubmed	The role of mannose-binding lectin-associated serine protease-3 in activation of the alternative complement pathway.	MASP1 MASP2	1.10e-06	2	37	2	21865552
Pubmed	Cooperation between MASP-1 and MASP-2 in the generation of C3 convertase through the MBL pathway.	MASP1 MASP2	1.10e-06	2	37	2	17182967
Pubmed	Synergy of protease-binding sites within the ecotin homodimer is crucial for inhibition of MASP enzymes and for blocking lectin pathway activation.	MASP1 MASP2	1.10e-06	2	37	2	35483450
Pubmed	Distinct Longitudinal Associations of MBL, MASP-1, MASP-2, MASP-3, and MAp44 With Endothelial Dysfunction and Intima-Media Thickness: The Cohort on Diabetes and Atherosclerosis Maastricht (CODAM) Study.	MASP1 MASP2	1.10e-06	2	37	2	27055907
Pubmed	Distinct pathways of mannan-binding lectin (MBL)- and C1-complex autoactivation revealed by reconstitution of MBL with recombinant MBL-associated serine protease-2.	MASP1 MASP2	3.30e-06	3	37	2	10925294
Pubmed	Two lineages of mannose-binding lectin-associated serine protease (MASP) in vertebrates.	MASP1 MASP2	3.30e-06	3	37	2	9794427
Pubmed	The mannan-binding lectin pathway of complement activation: biology and disease association.	MASP1 MASP2	3.30e-06	3	37	2	11532276
Pubmed	Mannan-binding lectin-associated serine protease (MASP)-1 is crucial for lectin pathway activation in human serum, whereas neither MASP-1 nor MASP-3 is required for alternative pathway function.	MASP1 MASP2	3.30e-06	3	37	2	22966085
Pubmed	Collectin-11/MASP complex formation triggers activation of the lectin complement pathway--the fifth lectin pathway initiation complex.	MASP1 MASP2	3.30e-06	3	37	2	23220946
Pubmed	Revised mechanism of complement lectin-pathway activation revealing the role of serine protease MASP-1 as the exclusive activator of MASP-2.	MASP1 MASP2	3.30e-06	3	37	2	22691502
Pubmed	Mannose-binding lectin binds to a range of clinically relevant microorganisms and promotes complement deposition.	MASP1 MASP2	3.30e-06	3	37	2	10639434
Pubmed	Extra-hepatic transcription of the human mannose-binding lectin gene (mbl2) and the MBL-associated serine protease 1-3 genes.	MASP1 MASP2	3.30e-06	3	37	2	16112196
Pubmed	Natural substrates and inhibitors of mannan-binding lectin-associated serine protease-1 and -2: a study on recombinant catalytic fragments.	MASP1 MASP2	3.30e-06	3	37	2	12538697
Pubmed	Oligomerization of Mannan-binding Lectin Dictates Binding Properties and Complement Activation.	MASP1 MASP2	3.30e-06	3	37	2	27104295
Pubmed	Interaction properties of human mannan-binding lectin (MBL)-associated serine proteases-1 and -2, MBL-associated protein 19, and MBL.	MASP1 MASP2	3.30e-06	3	37	2	11290788
Pubmed	Activation of the lectin complement pathway by H-ficolin (Hakata antigen).	MASP1 MASP2	3.30e-06	3	37	2	11907111
Pubmed	MASP interactions with plasma-derived MBL.	MASP1 MASP2	3.30e-06	3	37	2	22607836
Pubmed	Identification and characterization of BCL-3-binding protein: implications for transcription and DNA repair or recombination.	CREBBP N4BP2	6.60e-06	4	37	2	12730195
Pubmed	Co-complexes of MASP-1 and MASP-2 associated with the soluble pattern-recognition molecules drive lectin pathway activation in a manner inhibitable by MAp44.	MASP1 MASP2	6.60e-06	4	37	2	23785123
Pubmed	The chaperone and potential mannan-binding lectin (MBL) co-receptor calreticulin interacts with MBL through the binding site for MBL-associated serine proteases.	MASP1 MASP2	6.60e-06	4	37	2	18177377
Pubmed	Heteromeric complexes of native collectin kidney 1 and collectin liver 1 are found in the circulation with MASPs and activate the complement system.	MASP1 MASP2	6.60e-06	4	37	2	24174618
Pubmed	Cutting edge: complement-activating complex of ficolin and mannose-binding lectin-associated serine protease.	MASP1 MASP2	6.60e-06	4	37	2	10679061
Pubmed	Proteolytic activities of two types of mannose-binding lectin-associated serine protease.	MASP1 MASP2	6.60e-06	4	37	2	10946292
Pubmed	Characterization of the interaction between L-ficolin/p35 and mannan-binding lectin-associated serine proteases-1 and -2.	MASP1 MASP2	6.60e-06	4	37	2	12421953
Pubmed	Toward a structure-based comprehension of the lectin pathway of complement.	MASP1 MASP2	1.10e-05	5	37	2	23911397
Pubmed	A novel PCR-based technique using expressed sequence tags and gene homology for murine genetic mapping: localization of the complement genes.	MASP1 MASP2	1.10e-05	5	37	2	10700458
Pubmed	Essential role of mannose-binding lectin-associated serine protease-1 in activation of the complement factor D.	MASP1 MASP2	1.10e-05	5	37	2	20038603
Pubmed	Ficolin A and ficolin B are expressed in distinct ontogenic patterns and cell types in the mouse.	MASP1 MASP2	1.65e-05	6	37	2	15950722
Pubmed	Interaction of C1q and mannan-binding lectin (MBL) with C1r, C1s, MBL-associated serine proteases 1 and 2, and the MBL-associated protein MAp19.	MASP1 MASP2	1.65e-05	6	37	2	10878362
Pubmed	Developmental activities of the complement pathway in migrating neurons.	MASP1 MASP2	7.22e-05	12	37	2	28462915
Pubmed	Demethylation of H3K27 regulates polycomb recruitment and H2A ubiquitination.	PAXIP1 N4BP2	8.53e-05	13	37	2	17761849
Pubmed	A germline-specific class of small RNAs binds mammalian Piwi proteins.	ZNF778 ABL2 DSTYK ZNF689 ASH1L	1.10e-04	450	37	5	16751776
Pubmed	A human MAP kinase interactome.	LAMB1 NUP214 ABL2 CREBBP N4BP2	1.57e-04	486	37	5	20936779
Pubmed	Inflammation-dependent overexpression of c-Myc enhances CRL4DCAF4 E3 ligase activity and promotes ubiquitination of ST7 in colitis-associated cancer.	KNTC1 PHKA2 ABL2 ASH1L	1.59e-04	257	37	4	30945288
Pubmed	Fine expression profiling of full-length transcripts using a size-unbiased cDNA library prepared with the vector-capping method.	FLNB N4BP2	2.51e-04	22	37	2	18487259
Pubmed	An improved smaller biotin ligase for BioID proximity labeling.	MUC19 NUP214 ASH1L	3.07e-04	123	37	3	26912792
Pubmed	The Maternal Microbiome Programs the m6A Epitranscriptome of the Mouse Fetal Brain and Intestine.	ABL2 METTL4	3.25e-04	25	37	2	35874829
Pubmed	Localization of somatostatin receptor genes on mouse chromosomes 2, 11, 12, 15, and 17: correlation with growth QTLs.	LAMB1 LPA	3.52e-04	26	37	2	9226367
Pubmed	Functional proteomics mapping of a human signaling pathway.	PAXIP1 PHKA2 FLNB CREBBP ASH1L	3.87e-04	591	37	5	15231748
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	FLNB ABL2 CREBBP DSTYK	4.20e-04	332	37	4	37433992
Pubmed	Association between the SERPING1 gene and age-related macular degeneration: a two-stage case-control study.	MASP1 MASP2	5.35e-04	32	37	2	18842294
Pubmed	Analysis of early C2C12 myogenesis identifies stably and differentially expressed transcriptional regulators whose knock-down inhibits myoblast differentiation.	FOXN2 ZNF689	8.80e-04	41	37	2	22147266
Pubmed	A GO catalogue of human DNA-binding transcription factors.	ZNF469 ZNF45	9.23e-04	42	37	2	34673265
Pubmed	Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.	ZNF778 ZNF45 ZNF689	9.46e-04	181	37	3	37372979
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	FLNB NUP214 N4BP2 ATG2B	9.93e-04	418	37	4	34709266
Interaction	FCN2 interactions	MASP1 MASP2	1.75e-05	4	35	2	int:FCN2
ToppCell	COVID-19_Mild-PLT_4\|World / Disease Group and Platelet Clusters	UBE2F HEMGN ZNF778 FOXN2	1.94e-05	193	37	4	98a52523aa1efd5d14a2878ed106828a80a33aa2
ToppCell	COVID-19_Mild-PLT_4\|COVID-19_Mild / Disease Group and Platelet Clusters	UBE2F HEMGN ZNF778 FOXN2	2.14e-05	198	37	4	3d8c33dba759df0974aeb2b9a6b5167ae7a18e1f
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FLNB ABL2 DOCK11 DENND4B	2.19e-05	199	37	4	379bbd9cecf466b902411c54d74bd9885285b1ba
ToppCell	Neuronal-Excitatory-eA(LAMP5_LINC00507)-FREM3---L2-3\|Neuronal / cells hierarchy compared to all cells using T-Statistic	LAMB1 ZNF469 SHROOM3 SLIT3	2.23e-05	200	37	4	9c89e91bb630cc306a820927a36ea6fb3d13e9d7
ToppCell	Neuronal-Excitatory-eA(LAMP5_LINC00507)-FREM3--\|Neuronal / cells hierarchy compared to all cells using T-Statistic	LAMB1 ZNF469 SHROOM3 SLIT3	2.23e-05	200	37	4	96b1d2e70fbbba744fd4356a70efcf356aca9abc
ToppCell	Neuronal-Excitatory-eA(LAMP5_LINC00507)-FREM3\|Neuronal / cells hierarchy compared to all cells using T-Statistic	LAMB1 ZNF469 SHROOM3 SLIT3	2.23e-05	200	37	4	ad6f1d4d7f5d7bab2ba2e4fff58c535290065c0e
ToppCell	Neuronal-Excitatory-eA(LAMP5_LINC00507)-FREM3-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	LAMB1 ZNF469 SHROOM3 SLIT3	2.23e-05	200	37	4	8821574d17b55dfea3ca0204e6b4c0ca6b19588a
ToppCell	mild-immature_Neutrophil\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	KNTC1 ZNF778 ZNF780B	4.50e-05	83	37	3	f7225bc24ad6df3a41375cc4614af824e0db3559
Disease	aortic stenosis, aortic valve calcification	FLNB LPA	1.08e-03	42	34	2	EFO_0000266, EFO_0005239
Disease	myopathy (implicated_via_orthology)	FLNB MYBPC2	1.41e-03	48	34	2	DOID:423 (implicated_via_orthology)
Disease	glucose metabolism measurement, age-related hearing impairment	UBE2F ZNF469	1.65e-03	52	34	2	EFO_0005782, EFO_0009367
Disease	acute lymphoblastic leukemia (is_implicated_in)	NUP214 CREBBP	1.84e-03	55	34	2	DOID:9952 (is_implicated_in)
Disease	Precursor Cell Lymphoblastic Leukemia Lymphoma	NUP214 CREBBP	2.26e-03	61	34	2	C1961102
Disease	Ulcerative Colitis	LAMB1 MASP2	2.41e-03	63	34	2	C0009324
Disease	gut microbiome measurement, taxonomic microbiome measurement	FLNB SHROOM3	2.64e-03	66	34	2	EFO_0007874, EFO_0007883

Protein segments in the cluster

Peptide	Gene	Start	Entry
IVKHGEPAPYLCNKD	TPST1	146	O60507
TSKHEKQPPVYCTSP	ASH1L	516	Q9NR48
KQKQAEHVPPYDVVP	CACNB3	161	P54284
CNKPTVYGVSPIHDK	ABL2	266	P42684
DYIFHCHPPDQKIPK	CREBBP	1481	Q92793
KFQHEVYPPCKPDCD	ATG2B	1616	Q96BY7
CTHLIVPEPKGEKYE	PAXIP1	136	Q6ZW49
CVYKPMQPGPHVVKI	FLNB	416	O75369
HPIVNPKPYHEECKK	MUC19	1021	Q7Z5P9
KHPVCVKHPPSVKYA	EEF2KMT	56	Q96G04
KKVIPCPPFYESDHP	NUP214	226	P35658
PEPYCIVSHLQEDKK	LAMB1	61	P07942
TEYSKHCGKPVPPDT	KNTC1	2181	P50748
FPCALKSVVPPDEKH	DSTYK	676	Q6XUX3
PKYLPHKTCNEIIVP	HEMGN	321	Q9BXL5
KDVPKECFPEPHQET	HEMGN	416	Q9BXL5
TKMPNPHYLPEVCIK	DNAH6	3171	Q9C0G6
HCAEPYIKNSDPVKT	DOCK11	491	Q5JSL3
APPEKSPVVQDCYHG	LPA	1491	P08519
DHPEVPCPYDYIKIK	MASP1	236	P48740
PIVDHQKCTAAYEKP	MASP2	591	O00187
SCVEKVHPEQEKPEP	DENND4B	651	O75064
EHSPNKCLPVKEIYS	FOXN2	126	P32314
TKPYITPAVHKECQQ	METTL4	96	Q8N3J2
PPNKVDEEYKNPHTV	PHKA2	376	P46019
EVPDAYNMVPPKVKC	UBE2F	86	Q969M7
KYVPSKVHFCSVPEN	SHROOM3	551	Q8TF72
HQPELDPPRYKCTEK	C11orf1	126	Q9H5F2
VQKKEYVCPAPHSEP	SLIT3	256	O75094
KHVQTDPGQKPYECK	ZNF778	326	Q96MU6
KEKHLNTPYIVACDP	RNASE8	121	Q8TDE3
KEYPPHVQKVEINPV	SENP6	161	Q9GZR1
PQSIHTGEKPYECKE	ZNF780B	771	Q9Y6R6
NPHVYGKRCEKPVLP	ZNF469	2846	Q96JG9
SHKCAQNLKKPYPCP	ZNF689	166	Q96CS4
ASTVEKHCGKVPYPP	UGT2A1	176	P0DTE4
PLIVHTGEKPYKCEE	ZNF45	266	Q02386
HPELPTKGKDVSYCP	N4BP2	331	Q86UW6
EYVPKQEPPKIHLDC	MYBPC2	531	Q14324