Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunction3'-5' exonuclease activity

TOE1 POLG

1.52e-0361192GO:0008408
GeneOntologyMolecularFunctionexonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters

TOE1 POLG

1.57e-0362192GO:0016796
GeneOntologyMolecularFunctionexonuclease activity

TOE1 POLG

3.41e-0392192GO:0004527
GeneOntologyCellularComponentperineuronal net

TNR BCAN

3.51e-0510192GO:0072534
GeneOntologyCellularComponentperisynaptic extracellular matrix

TNR BCAN

4.28e-0511192GO:0098966
GeneOntologyCellularComponentsynapse-associated extracellular matrix

TNR BCAN

6.07e-0513192GO:0099535
MousePhenoabsent cochlear outer hair cells

COL11A1 JAG1

4.81e-0510152MP:0004403
DomainEGF_3

TNR BCAN JAG1 EGF

6.51e-05235184PS50026
DomainEGF

TNR BCAN JAG1 EGF

6.51e-05235184SM00181
DomainEGF-like_dom

TNR BCAN JAG1 EGF

8.15e-05249184IPR000742
DomainEGF_1

TNR BCAN JAG1 EGF

8.93e-05255184PS00022
DomainEGF-like_CS

TNR BCAN JAG1 EGF

9.77e-05261184IPR013032
DomainEGF_2

TNR BCAN JAG1 EGF

1.04e-04265184PS01186
DomainEGF

BCAN JAG1 EGF

2.27e-04126183PF00008
Domain-

TOE1 POLG

9.24e-04471823.30.420.10
DomainEGF_extracell

TNR JAG1

1.50e-0360182IPR013111
DomainEGF_2

TNR JAG1

1.50e-0360182PF07974
DomainRNaseH-like_dom

TOE1 POLG

1.98e-0369182IPR012337
DomainEGF_CA

JAG1 EGF

3.06e-0386182PF07645
DomainEGF_Ca-bd_CS

JAG1 EGF

3.87e-0397182IPR018097
DomainEGF_CA

JAG1 EGF

4.03e-0399182PS01187
DomainASX_HYDROXYL

JAG1 EGF

4.11e-03100182PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

JAG1 EGF

4.60e-03106182IPR000152
DomainEGF_CA

JAG1 EGF

6.05e-03122182SM00179
DomainEGF-like_Ca-bd_dom

JAG1 EGF

6.24e-03124182IPR001881
DomainGrowth_fac_rcpt_

JAG1 EGF

9.71e-03156182IPR009030
Pubmed

The C-type lectin domains of lecticans, a family of aggregating chondroitin sulfate proteoglycans, bind tenascin-R by protein-protein interactions independent of carbohydrate moiety.

TNR BCAN

8.48e-0731929294172
Pubmed

Brevican distinctively assembles extracellular components at the large diameter nodes of Ranvier in the CNS.

TNR BCAN

8.48e-07319219141078
Pubmed

Changes in resting-state functional connectivity after stroke in a mouse brain lacking extracellular matrix components.

TNR BCAN

1.70e-06419229367009
Pubmed

Extracellular matrix alterations in brains lacking four of its components.

TNR BCAN

1.70e-06419215694392
Pubmed

Elimination of the four extracellular matrix molecules tenascin-C, tenascin-R, brevican and neurocan alters the ratio of excitatory and inhibitory synapses.

TNR BCAN

1.70e-06419231558805
Pubmed

Primary hippocampal neurons, which lack four crucial extracellular matrix molecules, display abnormalities of synaptic structure and function and severe deficits in perineuronal net formation.

TNR BCAN

1.70e-06419223637166
Pubmed

Brevican, Neurocan, Tenascin-C, and Tenascin-R Act as Important Regulators of the Interplay Between Perineuronal Nets, Synaptic Integrity, Inhibitory Interneurons, and Otx2.

TNR BCAN

1.70e-06419235721494
Pubmed

Intrinsic cellular and molecular properties of in vivo hippocampal synaptic plasticity are altered in the absence of key synaptic matrix molecules.

TNR BCAN

1.70e-06419228512860
Pubmed

Neural extracellular matrix regulates visual sensory motor integration.

TNR BCAN

1.70e-06419238318351
Pubmed

The proteoglycans aggrecan and Versican form networks with fibulin-2 through their lectin domain binding.

TNR BCAN

2.82e-06519211038354
Pubmed

Candidate gene analysis of the human natural killer-1 carbohydrate pathway and perineuronal nets in schizophrenia: B3GAT2 is associated with disease risk and cortical surface area.

TNR BCAN

1.27e-051019220950796
Pubmed

Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia.

COL11A1 JAG1 KREMEN1 EGF

2.79e-0533119420634891
Pubmed

Fibroblast growth factor receptor-Frs2α signaling is critical for nephron progenitors.

JAG1 EGF

6.49e-052219225641696
Pubmed

Tet2- and Tet3- Mediated Cytosine Hydroxymethylation in Six2 Progenitor Cells in Mice Is Critical for Nephron Progenitor Differentiation and Nephron Endowment.

TET3 JAG1

1.48e-043319236522157
CoexpressionGSE7459_UNTREATED_VS_IL6_TREATED_ACT_CD4_TCELL_DN

SHISA9 JAG1 EGF DNAJC10

3.26e-06145194M463
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SHISA9 TNR BCAN COL11A1

1.29e-06196194671c380b58d7f634b4fbec38c357d357ea4f3535
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SHISA9 TNR BCAN COL11A1

1.29e-06196194f374cb3ec31c6eef2cef9e07547bfd1e380553af
ToppCellMacroglial-Polydendrocytes-PDGFRA----L1-6|Macroglial / cells hierarchy compared to all cells using T-Statistic

SHISA9 TNR BCAN COL11A1

1.39e-06200194310cd53db1c137f6af74e6ae682221d7ac27310c
ToppCellMacroglial-Polydendrocytes-PDGFRA|Macroglial / cells hierarchy compared to all cells using T-Statistic

SHISA9 TNR BCAN COL11A1

1.39e-06200194c24a3099e3d96d8b72f6d05286bb355d661a0377
ToppCellMacroglial-Polydendrocytes-PDGFRA---|Macroglial / cells hierarchy compared to all cells using T-Statistic

SHISA9 TNR BCAN COL11A1

1.39e-062001944fc3de4bff7ed2bf40b38462c4b4e9b87af6a4ca
ToppCellMacroglial-Polydendrocytes-PDGFRA-|Macroglial / cells hierarchy compared to all cells using T-Statistic

SHISA9 TNR BCAN COL11A1

1.39e-06200194f17b5a54e8f9eba9dcd0808ba4e8d275ac41bce2
ToppCellMacroglial-Polydendrocytes-PDGFRA--|Macroglial / cells hierarchy compared to all cells using T-Statistic

SHISA9 TNR BCAN COL11A1

1.39e-06200194cc3409518f8b436ea92deb955e81114b3f410ff7
ToppCellMacroglial-Polydendrocytes|Macroglial / cells hierarchy compared to all cells using T-Statistic

SHISA9 TNR BCAN COL11A1

1.39e-06200194961858738ce35db8760c8c2e136f8369bc444ccf
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Igfbp6_Pltp|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GLP1R COL11A1 THSD7B

1.92e-0512419336dfc702a570e1a1a6dde09f38badf9023ea7287
ToppCell21-Trachea-Epithelial-Submucosal_gland_basal|Trachea / Age, Tissue, Lineage and Cell class

ADCY5 BCAN THSD7B

4.03e-051591934f670b57b8d3b090ea2f1aafe15baf93cb7ef146
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell-D122|Adult / Lineage, Cell type, age group and donor

ADCY5 GLP1R JAG1

4.10e-05160193fd14dfeb7021a4b7299371854dc8fc1fd66c8dae
ToppCellfacs-Lung-EPCAM-3m-Endothelial-Capillary_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPWD1 TNR GLP1R

4.26e-051621931f1b93394b1f27cbb76b369c19b9313609edd577
ToppCellChildren_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADCY5 GLP1R JAG1

4.49e-051651938a82e20c9b1156bb4bbc16f7785abb04458d671b
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell|Adult / Lineage, Cell type, age group and donor

ADCY5 GLP1R JAG1

5.09e-05172193c62cad0f4212d1e9ea1ec3143ad3c4e06aff0ebf
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

GLP1R JAG1 THSD7B

5.63e-05178193066dbc4cc2083c549d98122ed44707127f34d582
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Macroglial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNR BCAN COL11A1

5.92e-051811931037051eb82313c13346617b33f3c4c648181c4d
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-OPC|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TNR BCAN COL11A1

6.02e-051821933cc61f5f7ad4a81eba3daf65e122880b5af3adc0
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-OPC|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TNR BCAN COL11A1

6.02e-051821938a8b08ac4bb3cba3541dbe234e088703842285b9
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TNR BCAN COL11A1

6.02e-051821935d909e4b5f662905bf1be9c686bbddc3e87d2be9
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TNR BCAN COL11A1

6.02e-05182193e36766309c4d96a90d213ce37d3acef1029a3fdc
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like-D|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SHISA9 TNR BCAN

6.11e-05183193a742c9a33f32058f9fb051733e3e736bc704d8e6
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_OPC-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TNR BCAN COL11A1

6.11e-051831938c8ce5a0d5535bef58ac10b7eb726f9c50af2ed8
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-OPC|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TNR BCAN COL11A1

6.31e-05185193fba2dc46cd98ab9c78e788959c2121aa10d148b2
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TNR BCAN COL11A1

6.31e-05185193efc5d564f8793c751ba640aef60f761e4b081d3f
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADCY5 GLP1R JAG1

6.42e-05186193a95744b8649096bd7cfc3591a02841fa411085b3
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_2-VSMC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ADCY5 GLP1R JAG1

6.42e-05186193c7885fd6dc7dc8fffc96f0112c51a365cf8a8f80
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_OPC|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SHISA9 BCAN COL11A1

6.42e-05186193aed57d1498fae4abe708aaad210900f2db2a189c
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADCY5 GLP1R JAG1

6.42e-051861934780af76237d7af2abbe2d8d5530cdf53e3ed0b7
ToppCellCOVID-19-Fibroblasts-Airway_smooth_muscle|COVID-19 / group, cell type (main and fine annotations)

ADCY5 COL11A1 JAG1

6.52e-05187193464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TNR BCAN COL11A1

6.52e-051871935b7a1edee602e55d3400dc17dbb6b8aaa26defc0
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-OPC|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TNR BCAN COL11A1

6.52e-05187193daff7ccd3f1924cf2b34d3aca3eccde245aaf371
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNR BCAN COL11A1

6.62e-05188193006db2c2c44971ca9241c582bc89f258c785f5ed
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNR BCAN COL11A1

6.62e-05188193d0e6fb4a3b3d79d3512b5500062ea285495ae526
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADCY5 GLP1R JAG1

6.73e-051891937fbe855bfdb47d35e040b04a80fe4b729a3764e8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADCY5 GLP1R JAG1

6.73e-0518919306b35abecd29f902cf251fcc1f6ad33db7ab08a2
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SHISA9 TNR COL11A1

6.83e-051901936c7e1086c0a274cd5527c3104106e372811c9905
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ADCY5 GLP1R JAG1

6.83e-05190193d6b3a92119b210974a32af3fe9875d60eb02761e
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADCY5 GLP1R JAG1

6.83e-0519019373d94fbae92029745989a8712eed8b99fd84c193
ToppCellMesenchymal-vascular_smooth_muscle_cell|World / Lineage, Cell type, age group and donor

ADCY5 GLP1R JAG1

6.94e-05191193fd89fbc62aa1c73e0f659991e3bd726a0c97bd68
ToppCellwk_20-22-Mesenchymal-Myofibro_&_SMC-Vascular_SMC_2|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ADCY5 GLP1R JAG1

7.05e-05192193a7d08416f07f29ad920168a3b52ddf992f263bf4
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_OPC|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TNR BCAN COL11A1

7.27e-05194193920955e775617d6156c5ee8b90d2cecd01a70e12
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-NPC-like|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TNR BCAN COL11A1

7.49e-05196193fe2dd3a93fe22da93e24a400e154a68757985fc8
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SHISA9 TNR BCAN

7.72e-0519819302d0d8a212e09c0962ab1dae6a885d26d357f66a
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TNR BCAN COL11A1

7.84e-05199193333056c2abe9724efeab542c0365fcfe4eff8f18
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TNR BCAN COL11A1

7.84e-05199193e60ecbb8fa7bcd3e2ce7d78f6efb2cfd1fd77698
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_Prolif-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TNR BCAN COL11A1

7.84e-0519919353b3d35767889a152f1f38e8f6f0ba8f7a7690f2
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-Macroglial-Astrocyte|GW10 / Sample Type, Dataset, Time_group, and Cell type.

MAMDC4 COL11A1 DNAJC10

7.96e-0520019398a994692440cb4f505b050276f0c8022c814a21
ToppCelldistal-3-mesenchymal-Airway_Smooth_Muscle|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ADCY5 GLP1R JAG1

7.96e-052001934072cfb3047954f507289587b4bfaf1526936992
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-Macroglial|GW10 / Sample Type, Dataset, Time_group, and Cell type.

MAMDC4 COL11A1 DNAJC10

7.96e-05200193ef222dc4a205d670172dae74990bdb952ac92e5b
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2.Synpr-Nnat_(Neuron.Gad1Gad2.Synpr-Nnat)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

GLP1R THSD7B

5.91e-04851922429bacccd103e5b2414264b4aff3103ed9d7cec
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2.Synpr-Nnat_(Neuron.Gad1Gad2.Synpr-Nnat)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

GLP1R THSD7B

5.91e-0485192642755ed2b562dd5e599a04a2b9730e8d29aefe8
ToppCell(05)_Ciliated-(1)_24hpi|(05)_Ciliated / shred by cell type and Timepoint

TNR POLG

6.33e-048819276959e7e3f6fae07c9881a29c28ba847be406694
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-Like-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHISA9 BCAN

6.77e-0491192b0658e020f80e56fab9d2aa07e321d9b33d7af2c
ToppCell368C-Epithelial_cells-Epithelial-B_(AT2)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

MAMDC4 EGF

9.33e-041071925bae4b3aede9bcbf7e88414e3453973cc8b0c3e7
ToppCell368C-Epithelial_cells-Epithelial-B_(AT2)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

MAMDC4 EGF

9.33e-04107192410b37beffaf637a2a64c9d0ce7baf81f4bc667c
ToppCellfacs-Thymus-Epithelium-3m-Lymphocytic-DN_to_DP_transition_(most_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPWD1 ARID2

9.86e-041101923a641dced828ed97a8eea70d0a7b76f33630c9be
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Gabrg1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GLP1R COL11A1

1.13e-031181923f0a304ef9c9e5ba047fc09f4372590eed624328
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-hematologic|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SHISA9 COL11A1

1.29e-03126192f2ec5aa6c649ae1ff99519f6897cf207dc292edf
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-hematologic-erythrocytic|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SHISA9 COL11A1

1.29e-03126192cd02f3d4a3fadd24f3a298639b392f0354d227d2
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-hematologic-erythrocytic-erythrocyte|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SHISA9 COL11A1

1.29e-0312619261a7e400cbc81691b21cd3c37376c1d19fec2270
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADCY5 EGF

1.39e-0313119272340ea139a6616a466b417949e273f473fba993
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_VISp_Car3|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

COL11A1 KREMEN1

1.46e-031341924ef5f395e321cf04e56560be2502a8aa157682f4
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

THSD7B EGF

1.48e-0313519252b5c664c0b7a303c6084d508748dcb6c38a0c23
ToppCellPND01-03-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_DCN|PND01-03-samps / Age Group, Lineage, Cell class and subclass

COL11A1 THSD7B

1.52e-03137192a69976938d4e89315ec0be3a332b91ddf3799d65
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADCY5 GLP1R

1.54e-03138192a88c3ae56b0af60f6e87cabade4f21e2bbb336f2
ToppCellCOVID-19-kidney-Technical/muscle_(PCT)|COVID-19 / Disease (COVID-19 only), tissue and cell type

TNR THSD7B

1.57e-03139192a1945b07f177cde40e7eea03a19236ce76165857
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Igfbp6_Pltp|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GLP1R THSD7B

1.57e-031391929e9f29f92dbe65b26cc78b3a1c00778c6a701f5b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_low-phase|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TNR THSD7B

1.68e-03144192f6061dd965a2b2fe6ad864f8aecc06d2e74881ce
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Reln_Itm2a|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

BCAN COL11A1

1.68e-031441920bbe670454846cf9bc7464ae4e91488415c4111d
ToppCellLPS-IL1RA-Endothelial-Mes-Like-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PPWD1 MAMDC4

1.70e-0314519290ca38c02325c5c637c32efdef634b54cc3cd105
ToppCellCOVID-19-kidney-Technical/muscle_(PCT)|kidney / Disease (COVID-19 only), tissue and cell type

TNR THSD7B

1.72e-03146192c55f1bdb6ac43b4118cb27ea7c879527e1afcbab
ToppCellE18.5-samps-Mesenchymal-Pericyte-pericyte_D|E18.5-samps / Age Group, Lineage, Cell class and subclass

SHISA9 COL11A1

1.80e-03149192dcf68eb25733b5db2893728fe4dca5c7267eb58c
ToppCell3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADCY5 JAG1

1.82e-03150192aa11579a57d671a55e64183d35c1340fda6dec14
ToppCellSubstantia_nigra-Macroglia-POLYDENDROCYTE|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

TNR BCAN

1.82e-0315019270ac8ae4b1683fb17278a8e4606f2fa0b94988c0
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L3-6_VIP_KCTD13|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GLP1R THSD7B

1.84e-031511921fd43cda3ac4d1c96560338fcfb6c346b1dec0a2
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

ARID2 KREMEN1

1.87e-03152192b8aa62e3cf2b4c252db4bccfa75d881c4fa0a788
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADCY5 EGF

1.89e-031531920307f10e772021ae68a42690634df458672a6df9
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SHISA9 TNR

1.94e-0315519277fdae85d36efb776db977eb424b32487ef222e4
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

POLG JAG1

1.94e-031551928e239470799426ea474a36f57e1b7e0d9365ca5f
ToppCellfacs-Lung-EPCAM-3m-Endothelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNR GLP1R

1.94e-031551920e942609d3e060f1e589fee5997fc6299f3d18bc
ToppCell10x5'-bone_marrow-Lymphocytic_Invariant-Inducer-like-ILC3|bone_marrow / Manually curated celltypes from each tissue

TNR JAG1

1.94e-0315519283430a64c2cb5ad29caa3dacba76c28dd204ac40
ToppCellfacs-Lung-EPCAM-3m-Endothelial-endothelial_cell_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNR GLP1R

1.97e-03156192bb64bf520cb74897a01c64924a85a1550df2b801
ToppCell5'-Adult-Appendix-Hematopoietic-B_cells-Cycling_B_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

THSD7B DNAJC10

1.97e-03156192203ef22eb76bd2b829b027c30af0557080f4006c
ToppCellGoblet|World / Class top

EGF DNAJC10

1.99e-03157192b352aa37d662629db6a9c6def9ee6d7c49a9071c
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal-cortical_neurons_1|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

ADCY5 THSD7B

2.01e-031581921f94622186d8329357fa06785e03eeacf29ab1ce
ToppCellLPS-antiTNF-Endothelial-Mes-Like|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHISA9 DNAJC10

2.01e-0315819250df52d64d07178975563abd98ce4fddb9f2f7ef
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell-D231|Adult / Lineage, Cell type, age group and donor

ADCY5 JAG1

2.01e-031581928d64c0c9de910a3f4658778642d183c8b9b6f6a2
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SHISA9 JAG1

2.01e-031581921cefb82b9bf79c687a119be568cfc15b14c6e040
ToppCellGoblet-gob-1|World / Class top

EGF DNAJC10

2.04e-0315919262d4ca2b538382419252e306d7a789b64420fb18
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_VIP_SOX11|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GLP1R THSD7B

2.04e-03159192ec725cccd2e58a5cd73dae5f9c9c334fdb9ef1a5
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-5_VIP_KCNJ2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

THSD7B EGF

2.04e-0315919251a7322efead3d4978e8f9fef71302bfae96edd7
ToppCelldroplet-Fat-SCAT-30m-Hematologic-erythroblast|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLP1R THSD7B

2.07e-03160192fc76337ad766c859db390ef8b6fb9caeaace3a56
ToppCelldroplet-Fat-SCAT-30m-Hematologic|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLP1R THSD7B

2.07e-03160192759749f708c3a2b36692d42499f19aff937e592f
ToppCelldroplet-Fat-SCAT-30m-Hematologic-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLP1R THSD7B

2.07e-0316019267ee7a314d7d4d3ea206e0158083f36f6dd7e80b
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell-D231|Adult / Lineage, Cell type, age group and donor

ADCY5 THSD7B

2.07e-03160192d783d29150033e9181c0e30870070268fed3fd85
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_VIP_TNFAIP8L3|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GLP1R JAG1

2.09e-03161192a14773afbe0e64662bfa5fce793cd9d05c24a9b5
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-plasmacytoid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAMDC4 EGF

2.09e-03161192ed93cb6c133855a5c244821e1a260aae8ab4df9a
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Plasmacytoid_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAMDC4 EGF

2.09e-031611920089d7bb305c592392791862a3341fc92af8f3e2
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ADCY5 GLP1R

2.14e-0316319251dee6c21cbeca4e17d1cc386e203f0c403089e8
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_4|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

TET3 DNAJC10

2.14e-031631929f5facfa1864eb63e2f8022ad7379d9252b7a254
Drugrhamnose

ADCY5 BCAN COL11A1 JAG1 EGF

8.82e-06356195CID000000840
DrugAC1L1JJ0

JAG1 EGF

1.38e-057192CID000005061
DrugJmv 320

JAG1 EGF

1.38e-057192CID003081775
Diseasehepatocellular carcinoma (is_implicated_in)

ARID2 POLG EGF

1.73e-04181183DOID:684 (is_implicated_in)
Diseasehemoglobin A1 measurement

ADCY5 GLP1R JAG1 EGF

2.40e-04520184EFO_0007629
Diseasespleen volume

ADCY5 EGF

3.13e-0443182EFO_0600047
Diseasechronic kidney disease

TET3 ADCY5 KREMEN1

3.73e-04235183EFO_0003884
DiseaseFamilial thoracic aortic aneurysm and aortic dissection

COL11A1 JAG1

4.75e-0453182C4707243
DiseaseAlcoholic Intoxication, Chronic

ADCY5 THSD7B EGF

5.46e-04268183C0001973
Diseaseosteoarthritis, hip, osteoarthritis, knee

COL11A1 THSD7B

6.50e-0462182EFO_0004616, EFO_1000786
DiseaseBenign Neoplasm

GLP1R DNAJC10

7.82e-0468182C0086692
DiseaseNeoplasms

GLP1R DNAJC10

7.82e-0468182C0027651
Diseasemultiple sclerosis (is_implicated_in)

POLG JAG1

9.00e-0473182DOID:2377 (is_implicated_in)
DiseaseGlioblastoma

JAG1 EGF

1.05e-0379182C0017636
DiseaseCleft Palate

COL11A1 EGF

1.11e-0381182C0008925
DiseaseGiant Cell Glioblastoma

JAG1 EGF

1.19e-0384182C0334588

Protein segments in the cluster

PeptideGeneStartEntry
GAPFACDFEQDPCGW

MAMDC4

61

Q6UXC1
DVYPGQCLWEGCEPF

ARID2

1661

Q68CP9
FCGSPWPNCNFPEYF

ADCY5

896

O95622
RFCNPGWDAFQGACY

BCAN

686

Q96GW7
QVCNSDPPCYEFLWG

MAGEB6

346

Q8N7X4
FDEYACWPDGEPGSF

GLP1R

66

P43220
DFPDGEYWIDPNQGC

COL11A1

1616

P12107
NGPYNDVDIPGCWFF

POLG

736

P54098
ACFCGNNPDYWKYGE

KREMEN1

166

Q96MU8
PVSWECDCFPGYDLQ

EGF

456

P01133
CQDFGWDPCFQPDGY

ITPA

146

Q9BY32
YAPWCGPCQNFAPEF

DNAJC10

696

Q8IXB1
DNWYRCECAPGFAGP

JAG1

801

P78504
FPGQCEWIYCPGDAI

PPWD1

176

Q96BP3
GYFDVMGQWDPPFNC

SHISA9

76

B4DS77
NEGWFGKNCSEPYCP

TNR

191

Q92752
NCNCDGPECPDYLEW

TET3

271

O43151
CPCDEFISQPYGNWS

THSD7B

921

Q9C0I4
DNFSAYGWCPLGPQC

TOE1

301

Q96GM8