Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionATP-dependent activity

MYD88 MYO1A ABCA13 MYO19 NVL RNF213 ATP9B ARID1A KIF20B DNAH1 BLM MCM9 SMARCA2 SMARCA4 DNA2 HSPA14

4.10e-0661413516GO:0140657
GeneOntologyMolecularFunctionubiquitin-like protein transferase activity

TRAF2 TRAF6 UBR4 MKRN2 HECTD4 RNF213 ZZEF1 TRIM24 BRAP ZNF451 ARIH1 HERC1 TRIM38 FBXW11

9.94e-0651213514GO:0019787
GeneOntologyMolecularFunctionaminoacyltransferase activity

TRAF2 TRAF6 UBR4 MKRN2 HECTD4 RNF213 ZZEF1 TRIM24 BRAP ZNF451 ARIH1 HERC1 TRIM38 FBXW11

1.53e-0553213514GO:0016755
GeneOntologyMolecularFunctionATP-dependent activity, acting on DNA

MYD88 ARID1A BLM MCM9 SMARCA2 SMARCA4 DNA2

2.51e-051271357GO:0008094
GeneOntologyMolecularFunctionacyltransferase activity

TRAF2 TRAF6 UBR4 MKRN2 HECTD4 RNF213 CHAT ZZEF1 TRIM24 BRAP ZDHHC23 ZNF451 ARIH1 HERC1 TRIM38 FBXW11

7.06e-0577513516GO:0016746
GeneOntologyMolecularFunctioncatalytic activity, acting on DNA

MYD88 POLG ARID1A BLM MCM9 SMARCA2 SMARCA4 POLN DNA2

7.45e-052621359GO:0140097
GeneOntologyMolecularFunctionubiquitin-like protein ligase activity

TRAF6 UBR4 MKRN2 RNF213 ZZEF1 TRIM24 BRAP ZNF451 ARIH1 TRIM38 FBXW11

8.44e-0539813511GO:0061659
GeneOntologyMolecularFunctionubiquitin-protein transferase activity

TRAF2 TRAF6 UBR4 MKRN2 HECTD4 RNF213 TRIM24 BRAP ARIH1 HERC1 TRIM38 FBXW11

9.02e-0547313512GO:0004842
GeneOntologyMolecularFunctionATP-dependent chromatin remodeler activity

MYD88 ARID1A SMARCA2 SMARCA4

1.11e-04371354GO:0140658
GeneOntologyMolecularFunctionATP hydrolysis activity

ABCA13 MYO19 NVL RNF213 ATP9B KIF20B BLM MCM9 SMARCA4 DNA2 HSPA14

2.07e-0444113511GO:0016887
GeneOntologyMolecularFunctionubiquitin protein ligase activity

TRAF6 UBR4 MKRN2 RNF213 TRIM24 BRAP ARIH1 TRIM38 FBXW11

9.78e-043721359GO:0061630
GeneOntologyMolecularFunctionlysine-acetylated histone binding

ZZEF1 TRIM24 SMARCA4

1.07e-03301353GO:0070577
GeneOntologyMolecularFunctionacetylation-dependent protein binding

ZZEF1 TRIM24 SMARCA4

1.18e-03311353GO:0140033
GeneOntologyBiologicalProcesspost-translational protein modification

USP53 USP34 TRAF2 TRAF6 GNL3L PARP8 UVSSA UBR4 MKRN2 HECTD4 RNF213 PARP14 ZZEF1 TRIM24 BRAP ATG4B ASB9 ZNF451 USP4 ARIH1 HERC1 FBXL2 TRIM38 FBXW11

1.02e-07107413424GO:0043687
GeneOntologyBiologicalProcessprotein modification by small protein conjugation or removal

USP53 USP34 TRAF2 TRAF6 GNL3L UVSSA UBR4 MKRN2 HECTD4 RNF213 ZZEF1 TRIM24 BRAP ASB9 ZNF451 USP4 ARIH1 HERC1 FBXL2 TRIM38 FBXW11

2.21e-06100913421GO:0070647
GeneOntologyBiologicalProcessprotein modification by small protein conjugation

TRAF2 TRAF6 GNL3L UVSSA UBR4 MKRN2 HECTD4 RNF213 ZZEF1 TRIM24 BRAP ASB9 ZNF451 USP4 ARIH1 HERC1 FBXL2 TRIM38 FBXW11

5.19e-0689313419GO:0032446
GeneOntologyBiologicalProcessprotein ubiquitination

TRAF2 TRAF6 GNL3L UVSSA UBR4 MKRN2 HECTD4 RNF213 ZZEF1 TRIM24 BRAP ASB9 USP4 ARIH1 HERC1 FBXL2 TRIM38 FBXW11

5.29e-0681113418GO:0016567
GeneOntologyBiologicalProcessmicrotubule bundle formation

CFAP47 SPACA9 PRC1 AK7 DNAH1 DNAAF5 CFAP46

4.58e-051451347GO:0001578
GeneOntologyBiologicalProcessmicrotubule cytoskeleton organization

CFAP47 RTTN RANBP9 SPACA9 PRC1 AK7 SPDL1 DNAH1 CEP350 DNAAF5 ZPR1 CEP295 STAG2 CFAP46 FBXW11

7.00e-0572013415GO:0000226
GeneOntologyBiologicalProcessinterleukin-17-mediated signaling pathway

TRAF2 TRAF6 IKBKE

7.31e-05131343GO:0097400
GeneOntologyBiologicalProcessaxoneme assembly

CFAP47 SPACA9 AK7 DNAH1 DNAAF5 CFAP46

7.87e-051091346GO:0035082
GeneOntologyCellularComponentbBAF complex

ARID1A SMARCA2 SMARCA4

2.86e-05101323GO:0140092
GeneOntologyCellularComponentnpBAF complex

ARID1A SMARCA2 SMARCA4

8.51e-05141323GO:0071564
GeneOntologyCellularComponentgamma DNA polymerase complex

POLG DNA2

1.18e-0431322GO:0005760
GeneOntologyCellularComponentnBAF complex

ARID1A SMARCA2 SMARCA4

1.30e-04161323GO:0071565
DomainARM-type_fold

USP34 IPO7 UBR4 RTTN NCBP1 ARID1A DNAAF5 IFRD1 UNC45B IFRD2 PUM1 STAG2

5.66e-0633913312IPR016024
DomainGln-Leu-Gln_QLQ

SMARCA2 SMARCA4

5.03e-0521332IPR014978
DomainIFRD_C

IFRD1 IFRD2

5.03e-0521332PF04836
DomainSnAC

SMARCA2 SMARCA4

5.03e-0521332PF14619
DomainQLQ

SMARCA2 SMARCA4

5.03e-0521332SM00951
DomainQLQ

SMARCA2 SMARCA4

5.03e-0521332PS51666
DomainIFRD

IFRD1 IFRD2

5.03e-0521332PF05004
DomainInterferon-rel_develop_reg_C

IFRD1 IFRD2

5.03e-0521332IPR006921
DomainSnAC

SMARCA2 SMARCA4

5.03e-0521332SM01314
DomainSnAC

SMARCA2 SMARCA4

5.03e-0521332IPR029295
DomainQLQ

SMARCA2 SMARCA4

5.03e-0521332PF08880
DomainInterferon-rel_develop_reg_N

IFRD1 IFRD2

5.03e-0521332IPR007701
DomainARM-like

IPO7 RTTN ARID1A DNAAF5 IFRD1 UNC45B IFRD2 PUM1 STAG2

1.38e-042701339IPR011989
DomainDNA_pol_A

POLG POLN

1.50e-0431332PF00476
DomainDNA-dir_DNA_pol_A_palm_dom

POLG POLN

1.50e-0431332IPR001098
DomainDNA_POLYMERASE_A

POLG POLN

1.50e-0431332PS00447
DomainPOLAc

POLG POLN

1.50e-0431332SM00482
Domain-

IPO7 RTTN ARID1A DNAAF5 IFRD1 UNC45B IFRD2 PUM1

1.93e-0422213381.25.10.10
DomainHSA

SMARCA2 SMARCA4

2.99e-0441332SM00573
DomainHSA

SMARCA2 SMARCA4

2.99e-0441332PS51204
DomainHSA_dom

SMARCA2 SMARCA4

2.99e-0441332IPR014012
DomainHSA

SMARCA2 SMARCA4

2.99e-0441332PF07529
DomainP-loop_NTPase

GNL3L MYO1A ABCA13 MYO19 NVL RNF213 CMSS1 AK7 KIF20B DNAH1 BLM MTHFD1 MCM9 SMARCA2 SMARCA4 DNA2

3.52e-0484813316IPR027417
DomainBRK

SMARCA2 SMARCA4

7.41e-0461332SM00592
DomainRIH_assoc-dom

RYR1 ITPR3

7.41e-0461332IPR013662
DomainCLTH

RANBP9 GID8

7.41e-0461332PF10607
DomainCRA

RANBP9 GID8

7.41e-0461332SM00757
DomainCTLH/CRA

RANBP9 GID8

7.41e-0461332IPR024964
DomainBRK_domain

SMARCA2 SMARCA4

7.41e-0461332IPR006576
DomainIns145_P3_rec

RYR1 ITPR3

7.41e-0461332PF08709
DomainTNF_rcpt--assoc_TRAF

TRAF2 TRAF6

7.41e-0461332IPR012227
DomainRIH_assoc

RYR1 ITPR3

7.41e-0461332PF08454
DomainRIH_dom

RYR1 ITPR3

7.41e-0461332IPR000699
DomainIns145_P3_rcpt

RYR1 ITPR3

7.41e-0461332IPR014821
DomainRyanodine_recept-rel

RYR1 ITPR3

7.41e-0461332IPR015925
Domain-

RYR1 ITPR3

7.41e-04613321.25.10.30
DomainRYDR_ITPR

RYR1 ITPR3

7.41e-0461332PF01365
DomainLiprin

PPFIA4 PPFIA3

7.41e-0461332IPR029515
DomainCRA_dom

RANBP9 GID8

7.41e-0461332IPR013144
DomainBRK

SMARCA2 SMARCA4

7.41e-0461332PF07533
DomainBromodomain_CS

TRIM24 SMARCA2 SMARCA4

8.14e-04261333IPR018359
Domain-

GNL3L ABCA13 MYO19 NVL RNF213 CMSS1 AK7 DNAH1 BLM MTHFD1 MCM9 SMARCA2 SMARCA4 DNA2

8.81e-04746133143.40.50.300
Domainzf-C3HC4

TRAF2 TRAF6 MKRN2 RNF213 TRIM24 BRAP TRIM38

1.10e-032231337PF00097
DomainZF_RING_2

TRAF2 TRAF6 MKRN2 RNF213 TRIM24 BRAP ARIH1 TRIM38

1.34e-032981338PS50089
Domainzf-TRAF

TRAF2 TRAF6

1.37e-0381332PF02176
Domain-

TRAF2 TRAF6 KDM5A MKRN2 RNF213 TRIM24 BRAP ARIH1 TRIM38 KDM4B

1.42e-03449133103.30.40.10
DomainJMJC

KDM5A HSPBAP1 KDM4B

1.51e-03321333PS51184
DomainJmjC_dom

KDM5A HSPBAP1 KDM4B

1.51e-03321333IPR003347
DomainRING

TRAF2 TRAF6 MKRN2 RNF213 TRIM24 BRAP ARIH1 TRIM38

1.55e-033051338SM00184
DomainJmjC

KDM5A HSPBAP1 KDM4B

1.65e-03331333SM00558
DomainZnf_RING/FYVE/PHD

TRAF2 TRAF6 KDM5A MKRN2 RNF213 TRIM24 BRAP ARIH1 TRIM38 KDM4B

1.67e-0345913310IPR013083
DomainLisH

RANBP9 GID8

1.75e-0391332PF08513
DomainCTLH

RANBP9 GID8

1.75e-0391332SM00668
DomainMIR

RYR1 ITPR3

2.18e-03101332PF02815
DomainJmjN

KDM5A KDM4B

2.18e-03101332SM00545
DomainMIR_motif

RYR1 ITPR3

2.18e-03101332IPR016093
DomainJmjN

KDM5A KDM4B

2.18e-03101332PF02375
DomainCTLH_C

RANBP9 GID8

2.18e-03101332IPR006595
DomainMIR

RYR1 ITPR3

2.18e-03101332PS50919
DomainMIR

RYR1 ITPR3

2.18e-03101332SM00472
DomainJMJN

KDM5A KDM4B

2.18e-03101332PS51183
DomainCTLH

RANBP9 GID8

2.18e-03101332PS50897
DomainJmjN

KDM5A KDM4B

2.18e-03101332IPR003349
DomainBROMODOMAIN_1

TRIM24 SMARCA2 SMARCA4

2.30e-03371333PS00633
DomainZnf_RING

TRAF2 TRAF6 MKRN2 RNF213 TRIM24 BRAP ARIH1 TRIM38

2.35e-033261338IPR001841
DomainBromodomain

TRIM24 SMARCA2 SMARCA4

2.48e-03381333PF00439
DomainBROMODOMAIN_2

TRIM24 SMARCA2 SMARCA4

3.09e-03411333PS50014
DomainMATH

TRAF2 TRAF6

3.17e-03121332PS50144
DomainZnf_TRAF

TRAF2 TRAF6

3.17e-03121332IPR001293
DomainPeptidase_M28

ERMP1 NCLN

3.17e-03121332PF04389
DomainPeptidase_M28

ERMP1 NCLN

3.17e-03121332IPR007484
DomainMATH/TRAF_dom

TRAF2 TRAF6

3.17e-03121332IPR002083
DomainMATH

TRAF2 TRAF6

3.17e-03121332SM00061
DomainMATH

TRAF2 TRAF6

3.17e-03121332PF00917
DomainBromodomain

TRIM24 SMARCA2 SMARCA4

3.31e-03421333IPR001487
DomainBROMO

TRIM24 SMARCA2 SMARCA4

3.31e-03421333SM00297
Domain-

TRIM24 SMARCA2 SMARCA4

3.31e-034213331.20.920.10
DomainSPRY

RANBP9 RYR1 HERC1 TRIM38

3.47e-03871334SM00449
DomainZF_TRAF

TRAF2 TRAF6

3.73e-03131332PS50145
DomainFA

FARP1 FRMD3

3.73e-03131332PF08736
DomainFERM-adjacent

FARP1 FRMD3

3.73e-03131332IPR014847
DomainFA

FARP1 FRMD3

3.73e-03131332SM01195
Domain-

TRAF2 TRAF6

4.33e-031413322.60.210.10
DomainSPRY

RANBP9 RYR1 HERC1 TRIM38

4.57e-03941334PF00622
DomainSPRY_dom

RANBP9 RYR1 HERC1 TRIM38

4.57e-03941334IPR003877
DomainB30.2/SPRY

RANBP9 RYR1 HERC1 TRIM38

4.75e-03951334IPR001870
DomainB302_SPRY

RANBP9 RYR1 HERC1 TRIM38

4.75e-03951334PS50188
DomainConA-like_dom

RANBP9 LAMA3 RYR1 CELSR2 HERC1 TRIM38

4.85e-032191336IPR013320
DomainZF_RING_1

TRAF2 TRAF6 MKRN2 TRIM24 BRAP ARIH1 TRIM38

4.87e-032911337PS00518
Domain-

KDM5A ARID1A

4.97e-031513321.10.150.60
DomainBRIGHT

KDM5A ARID1A

4.97e-03151332SM00501
DomainARID_dom

KDM5A ARID1A

4.97e-03151332IPR001606
DomainARID

KDM5A ARID1A

4.97e-03151332PS51011
DomainARID

KDM5A ARID1A

4.97e-03151332PF01388
DomainFBOX

FBXL2 FBXO34 FBXW11

6.05e-03521333SM00256
DomainZnf_RING_CS

TRAF2 TRAF6 MKRN2 TRIM24 TRIM38

6.25e-031631335IPR017907
DomainPoly(ADP-ribose)pol_cat_dom

PARP8 PARP14

6.38e-03171332IPR012317
DomainPARP_CATALYTIC

PARP8 PARP14

6.38e-03171332PS51059
DomainPARP

PARP8 PARP14

6.38e-03171332PF00644
Domain-

PARP8 PARP14

6.38e-031713323.90.228.10
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

USP34 POLG UBR4 RTTN HECTD4 LMNB2 NCLN ARID1A ZZEF1 LDLR RYR1 ITPR3 CELSR2 PLA2G4B IFRD2 LRRC56 STK40 HERC1 HAS3 SIPA1L2 PUM1 ABTB2 ARAP1

5.87e-1111051362335748872
Pubmed

Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity.

TRAF2 TRAF6 UBR4 HECTD4 RNF213 BRAP ARIH1 HERC1

4.06e-0995136829643511
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

TRAF2 PLVAP IPO7 UBR4 PPFIA3 CMSS1 NCLN ARID1A INTS3 TRIM24 RYR1 ITPR3 CEP350 SMARCA2 CEP295 STAG2

4.67e-096381361631182584
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

CFAP47 HSPBAP1 MYO19 UBR4 RNF213 PBX4 NCBP1 LMNB2 AGPS PPFIA3 PARP14 ZZEF1 RYR1 MTHFD1 CEP295 TNR FBXO34

5.06e-097361361729676528
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

USP53 MYD88 GNL3L POLG UVSSA HECTD4 LAMA3 RNF213 ATP9B ARID1A INTS3 DNAH1 RLF DNAAF5 IFRD1 FARP1 SMARCA2 ARIH1 STAG2 KDM4B ARAP1 FRMD3 FBXW11

1.73e-0814891362328611215
Pubmed

Ubiquitin-specific protease 4 (USP4) targets TRAF2 and TRAF6 for deubiquitination and inhibits TNFα-induced cancer cell migration.

TRAF2 TRAF6 USP4

5.85e-083136322029577
Pubmed

Clinicopathological and prognostic significance of SWI/SNF complex subunits in undifferentiated gastric carcinoma.

ARID1A SMARCA2 SMARCA4

5.85e-083136336464671
Pubmed

Defining the membrane proteome of NK cells.

GNL3L IPO7 UBR4 NVL RNF213 ERMP1 AGPS NCLN PEX11B PARP14 LDLR ITPR3 CEP350 MTHFD1 BUB1 SMARCA4 CORO7 HSPA14 STAG2

1.58e-0711681361919946888
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

GNL3L IPO7 UBR4 LMNB2 CMSS1 NCLN PEX11B ITPR3 DNAAF5 IFRD1 LRIG1 CORO7 PUM1 HSPA14 STAG2 CAPN15 CDK4

1.78e-079421361731073040
Pubmed

The clinicopathological significance of SWI/SNF alterations in gastric cancer is associated with the molecular subtypes.

ARID1A SMARCA2 SMARCA4

2.33e-074136333481850
Pubmed

Loss of the SWI/SNF-ATPase subunit members SMARCF1 (ARID1A), SMARCA2 (BRM), SMARCA4 (BRG1) and SMARCB1 (INI1) in oesophageal adenocarcinoma.

ARID1A SMARCA2 SMARCA4

2.33e-074136331906887
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

MYO1A KDM5A UBR4 LMNB2 CMSS1 PRC1 INTS3 TRIM24 BLM IFRD1 SMARCA4 STK40 PUM1 HSPA14 STAG2 FBXW11

2.68e-078571361625609649
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

TRAF2 GNL3L IPO7 PMPCB MYO19 UBR4 RANBP9 LMNB2 AGPS CMSS1 ARID1A KIF20B BLM RLF ATG4B MTHFD1 SMARCA2 SMARCA4 CORO7 PUM1

3.32e-0713531362029467282
Pubmed

An Interaction Landscape of Ubiquitin Signaling.

CCDC14 RABEP2 UBR4 HECTD4 NVL RNF213 BRAP ITPR3 ZNF451 USP4 HERC1 CAPN15

4.61e-074811361228190767
Pubmed

Largest subunits of the human SWI/SNF chromatin-remodeling complex promote transcriptional activation by steroid hormone receptors.

ARID1A SMARCA2 SMARCA4

5.82e-075136312200431
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

GNL3L IPO7 KDM5A NVL NCBP1 TRIM24 KIF20B BLM RLF ZNF451 SMARCA4 STAG2 KDM4B

8.53e-076081361336089195
Pubmed

Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.

ARID1A TRIM24 SMARCA2 SMARCA4 STAG2 CDK4

9.43e-0783136628794006
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

TRAF2 GNL3L PMPCB ARID1A LDLR METAP1 MTHFD1 PLA2G4B DGKK SMARCA2 SMARCA4 USP4 ARIH1 CDK4

1.15e-067301361434857952
Pubmed

Testing for association between MeCP2 and the brahma-associated SWI/SNF chromatin-remodeling complex.

ARID1A SMARCA2 SMARCA4

1.16e-066136316940996
Pubmed

Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies.

LDLR CELSR2 ZPR1

1.16e-066136322003152
Pubmed

The p270 (ARID1A/SMARCF1) subunit of mammalian SWI/SNF-related complexes is essential for normal cell cycle arrest.

ARID1A SMARCA2 SMARCA4

1.16e-066136316230384
Pubmed

Numerous BAF complex genes are mutated in Coffin-Siris syndrome.

ARID1A SMARCA2 SMARCA4

1.16e-066136325081545
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

USP34 IPO7 PMPCB ANXA3 UBR4 RANBP9 NCLN ITPR3 DNAAF5 PTPRD WDR97 GID8 SIPA1L2 CORO7 ABTB2 FBXW11

1.44e-069741361628675297
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

USP34 TRAF2 GNL3L KDM5A RANBP9 RNF213 PPFIA3 ARID1A ZZEF1 TRIM24 LDLR SMARCA2 SMARCA4 CEP295 SIGLEC1 SIPA1L2 DNA2

1.83e-0611161361731753913
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

USP34 IPO7 UBR4 NVL NCBP1 LMNB2 ARID1A ITPR3 BLM SMARCA2 SMARCA4 PUM1 STAG2

1.88e-066531361322586326
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

TCEA1 USP34 IPO7 ANXA3 UBR4 NVL RNF213 NCBP1 LMNB2 PRC1 BLM ZNF451 SMARCA2 SMARCA4 ARIH1 STAG2

2.41e-0610141361632416067
Pubmed

Epigenetic regulation by BAF (mSWI/SNF) chromatin remodeling complexes is indispensable for embryonic development.

ARID1A SMARCA2 SMARCA4

3.23e-068136326986003
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

CCDC14 RABEP2 IPO7 PMPCB RNF213 NCBP1 PPFIA3 ARID1A ITPR3 CEP350 BLM PTPRD FARP1 HERC1 PUM1 FBXW11

3.71e-0610491361627880917
Pubmed

MAVS activates TBK1 and IKKε through TRAFs in NEMO dependent and independent manner.

TRAF2 TRAF6 IKBKE

4.83e-069136329125880
Pubmed

Competition between TRAF2 and TRAF6 regulates NF-kappaB activation in human B lymphocytes.

TRAF2 TRAF6 IKBKE

4.83e-069136320449947
Pubmed

IFN-induced TPR protein IFIT3 potentiates antiviral signaling by bridging MAVS and TBK1.

TRAF2 TRAF6 IKBKE

4.83e-069136321813773
Pubmed

IKKε-mediated tumorigenesis requires K63-linked polyubiquitination by a cIAP1/cIAP2/TRAF2 E3 ubiquitin ligase complex.

MYD88 TRAF2 IKBKE

4.83e-069136323453969
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

USP34 GNL3L NVL RNF213 LMNB2 BRAP SPDL1 CEP350 ZNF451 SMARCA4 CEP295 CORO7 PUM1

6.55e-067331361334672954
Pubmed

SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.

TCEA1 HECTD4 RNF213 LMNB2 PARP14 SMARCA2 SMARCA4 DNA2

6.79e-06250136833536335
Pubmed

β-TrCP-mediated IRAK1 degradation releases TAK1-TRAF6 from the membrane to the cytosol for TAK1-dependent NF-κB activation.

MYD88 TRAF6 FBXW11

6.88e-0610136322851693
Pubmed

The transmembrane activator TACI triggers immunoglobulin class switching by activating B cells through the adaptor MyD88.

MYD88 TRAF2 TRAF6

6.88e-0610136320676093
Pubmed

UBE2O negatively regulates TRAF6-mediated NF-κB activation by inhibiting TRAF6 polyubiquitination.

MYD88 TRAF2 TRAF6

6.88e-0610136323381138
Pubmed

ARID1a-DNA interactions are required for promoter occupancy by SWI/SNF.

ARID1A SMARCA2 SMARCA4

6.88e-0610136323129809
Pubmed

CpG DNA prevents liver injury and shock-mediated death by modulating expression of interleukin-1 receptor-associated kinases.

MYD88 TRAF6 LDLR

6.88e-0610136318378686
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

USP53 USP34 UVSSA HECTD4 ERMP1 ZZEF1 METAP1 ATG4B DNA2 KDM4B ARAP1

8.00e-065291361114621295
Pubmed

TRIM38 inhibits TNFα- and IL-1β-triggered NF-κB activation by mediating lysosome-dependent degradation of TAB2/3.

TRAF2 TRAF6 TRIM38

9.43e-0611136324434549
Pubmed

The p97/VCP segregase is essential for arsenic-induced degradation of PML and PML-RARA.

USP34 TRAF2 RNF213 NCBP1 PARP14 TRIM24 MTHFD1 ZNF451

9.56e-06262136836880596
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

HECTD4 NVL AGPS PRC1 ARID1A ITPR3 BLM SMARCA2 SMARCA4 THAP12

9.77e-064401361034244565
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

USP34 TRAF2 TRAF6 ZBTB38 KDM5A POLG UBR4 HECTD4 RANBP9 NCBP1 ARID1A CEP350 METAP1 PTPRD ZNF451 SMARCA4 FBXW11

1.17e-0512851361735914814
Pubmed

Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair.

IPO7 PMPCB NVL TRIM24 SPDL1 CEP350 BLM MTHFD1 CORO7

1.22e-05357136937059091
Pubmed

Chemosensory Cell-Derived Acetylcholine Drives Tracheal Mucociliary Clearance in Response to Virulence-Associated Formyl Peptides.

CHAT ITPR3 NOS3

1.25e-0512136332294408
Pubmed

Brazilin selectively disrupts proximal IL-1 receptor signaling complex formation by targeting an IKK-upstream signaling components.

MYD88 TRAF2 TRAF6

1.25e-0512136324735611
Pubmed

Liprins, a family of LAR transmembrane protein-tyrosine phosphatase-interacting proteins.

PPFIA4 PPFIA3 PTPRD

1.25e-051213639624153
Pubmed

SYT associates with human SNF/SWI complexes and the C-terminal region of its fusion partner SSX1 targets histones.

ARID1A SMARCA2 SMARCA4

1.25e-0512136311734557
Pubmed

Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.

USP34 ANXA3 ERMP1 LMNB2 PEX11B ARID1A TRIM24 DNAAF5 SMARCA2 PUM1

1.35e-054571361032344865
Pubmed

The hbrm and BRG-1 proteins, components of the human SNF/SWI complex, are phosphorylated and excluded from the condensed chromosomes during mitosis.

SMARCA2 SMARCA4

1.52e-05213628670841
Pubmed

Lung cancer with loss of BRG1/BRM, shows epithelial mesenchymal transition phenotype and distinct histologic and genetic features.

SMARCA2 SMARCA4

1.52e-052136223163725
Pubmed

Treg-mediated suppression of atherosclerosis requires MYD88 signaling in DCs.

MYD88 LDLR

1.52e-052136223257360
Pubmed

Glycosylation of a CNS-specific extracellular matrix glycoprotein, tenascin-R, is dominated by O-linked sialylated glycans and "brain-type" neutral N-glycans.

SIGLEC1 TNR

1.52e-052136210406848
Pubmed

Combined gene dosage requirement for SWI/SNF catalytic subunits during early mammalian development.

SMARCA2 SMARCA4

1.52e-052136223076393
Pubmed

The SWI/SNF chromatin remodeling protein Brg1 is required for vertebrate neurogenesis and mediates transactivation of Ngn and NeuroD.

SMARCA2 SMARCA4

1.52e-052136215576411
Pubmed

Chromatin remodeling factors and BRM/BRG1 expression as prognostic indicators in non-small cell lung cancer.

SMARCA2 SMARCA4

1.52e-052136215240517
Pubmed

Concomitant loss of SMARCA2 and SMARCA4 expression in small cell carcinoma of the ovary, hypercalcemic type.

SMARCA2 SMARCA4

1.52e-052136226564006
Pubmed

SMARCA4/SMARCA2-deficient Carcinoma of the Esophagus and Gastroesophageal Junction.

SMARCA2 SMARCA4

1.52e-052136233027072
Pubmed

A synthetic lethality-based strategy to treat cancers harboring a genetic deficiency in the chromatin remodeling factor BRG1.

SMARCA2 SMARCA4

1.52e-052136223872584
Pubmed

Alterations of the SWI/SNF chromatin remodelling subunit-BRG1 and BRM in hepatocellular carcinoma.

SMARCA2 SMARCA4

1.52e-052136223088494
Pubmed

SWI/SNF chromatin remodeling enzyme ATPases promote cell proliferation in normal mammary epithelial cells.

SMARCA2 SMARCA4

1.52e-052136220333683
Pubmed

SWI/SNF Complex-deficient Undifferentiated Carcinoma of the Gastrointestinal Tract: Clinicopathologic Study of 30 Cases With an Emphasis on Variable Morphology, Immune Features, and the Prognostic Significance of Different SMARCA4 and SMARCA2 Subunit Deficiencies.

SMARCA2 SMARCA4

1.52e-052136234812766
Pubmed

Targeting of BRM Sensitizes BRG1-Mutant Lung Cancer Cell Lines to Radiotherapy.

SMARCA2 SMARCA4

1.52e-052136230478150
Pubmed

Sialoadhesin promotes rapid proinflammatory and type I IFN responses to a sialylated pathogen, Campylobacter jejuni.

MYD88 SIGLEC1

1.52e-052136222851711
Pubmed

Low-intensity pulsed ultrasound (LIPUS) prevents periprosthetic inflammatory loosening through FBXL2-TRAF6 ubiquitination pathway.

TRAF6 FBXL2

1.52e-052136228378753
Pubmed

The SWI/SNF ATPases Are Required for Triple Negative Breast Cancer Cell Proliferation.

SMARCA2 SMARCA4

1.52e-052136225808524
Pubmed

Antagonistic roles for BRM and BRG1 SWI/SNF complexes in differentiation.

SMARCA2 SMARCA4

1.52e-052136219144648
Pubmed

Blood pressure regulation by CD4+ lymphocytes expressing choline acetyltransferase.

CHAT NOS3

1.52e-052136227617738
Pubmed

Characterization of mammalian orthologues of the Drosophila osa gene: cDNA cloning, expression, chromosomal localization, and direct physical interaction with Brahma chromatin-remodeling complex.

ARID1A SMARCA2

1.52e-052136211318604
Pubmed

TLR-independent anti-inflammatory function of intestinal epithelial TRAF6 signalling prevents DSS-induced colitis in mice.

MYD88 TRAF6

1.52e-052136225761602
Pubmed

High expression of SMARCA4 or SMARCA2 is frequently associated with an opposite prognosis in cancer.

SMARCA2 SMARCA4

1.52e-052136229391527
Pubmed

Expression of SMARCA2 and SMARCA4 in gastric adenocarcinoma and construction of a nomogram prognostic model.

SMARCA2 SMARCA4

1.52e-052136237634210
Pubmed

Two human homologues of Saccharomyces cerevisiae SWI2/SNF2 and Drosophila brahma are transcriptional coactivators cooperating with the estrogen receptor and the retinoic acid receptor.

SMARCA2 SMARCA4

1.52e-05213628208605
Pubmed

A Brg1 null mutation in the mouse reveals functional differences among mammalian SWI/SNF complexes.

SMARCA2 SMARCA4

1.52e-052136211163203
Pubmed

Transcriptional specificity of human SWI/SNF BRG1 and BRM chromatin remodeling complexes.

SMARCA2 SMARCA4

1.52e-052136212620226
Pubmed

BRG1 and BRM SWI/SNF ATPases redundantly maintain cardiomyocyte homeostasis by regulating cardiomyocyte mitophagy and mitochondrial dynamics in vivo.

SMARCA2 SMARCA4

1.52e-052136227039070
Pubmed

Partial Inactivation of the Chromatin Remodelers SMARCA2 and SMARCA4 in Virus-Infected Cells by Caspase-Mediated Cleavage.

SMARCA2 SMARCA4

1.52e-052136229848589
Pubmed

E3 ubiquitin ligase tripartite motif 38 negatively regulates TLR-mediated immune responses by proteasomal degradation of TNF receptor-associated factor 6 in macrophages.

TRAF6 TRIM38

1.52e-052136222323536
Pubmed

Polymorphisms at LDLR locus may be associated with coronary artery disease through modulation of coagulation factor VIII activity and independently from lipid profile.

LDLR SMARCA4

1.52e-052136220810930
Pubmed

Differential preimplantation regulation of two mouse homologues of the yeast SWI2 protein.

SMARCA2 SMARCA4

1.52e-05213629603422
Pubmed

[G894T (NOS3) and G1958A (MTHFD1) gene polymorphisms and risk of ischemic heart disease in Yucatan, Mexico].

MTHFD1 NOS3

1.52e-052136225304051
Pubmed

Tumor progression by epithelial-mesenchymal transition in ARID1A- and SMARCA4-aberrant solid-type poorly differentiated gastric adenocarcinoma.

ARID1A SMARCA4

1.52e-052136234997313
Pubmed

SWI/SNF gene variants and glioma risk and outcome.

SMARCA2 SMARCA4

1.52e-052136223276717
Pubmed

Differential Expression of SWI/SNF Chromatin Remodeler Subunits Brahma and Brahma-Related Gene During Drug-Induced Liver Injury and Regeneration in Mouse Model.

SMARCA2 SMARCA4

1.52e-052136227097303
Pubmed

SMARCA4 and SMARCA2 deficiency in non-small cell lung cancer: immunohistochemical survey of 316 consecutive specimens.

SMARCA2 SMARCA4

1.52e-052136228038711
Pubmed

Proinflammatory stimuli engage Brahma related gene 1 and Brahma in endothelial injury.

SMARCA2 SMARCA4

1.52e-052136223963727
Pubmed

SW13 cells can transition between two distinct subtypes by switching expression of BRG1 and Brm genes at the post-transcriptional level.

SMARCA2 SMARCA4

1.52e-052136212493776
Pubmed

Heterozygous Mutations in SMARCA2 Reprogram the Enhancer Landscape by Global Retargeting of SMARCA4.

SMARCA2 SMARCA4

1.52e-052136231375262
Pubmed

Aberrant expression of SWI/SNF catalytic subunits BRG1/BRM is associated with tumor development and increased invasiveness in prostate cancers.

SMARCA2 SMARCA4

1.52e-052136217075831
Pubmed

Oncogenic role of MPHOSPH1, a cancer-testis antigen specific to human bladder cancer.

PRC1 KIF20B

1.52e-052136217409436
Pubmed

TRAF6 mediates human DNA2 polyubiquitination and nuclear localization to maintain nuclear genome integrity.

TRAF6 DNA2

1.52e-052136231216032
Pubmed

Loss of SWI/SNF Chromatin Remodeling Alters NRF2 Signaling in Non-Small Cell Lung Carcinoma.

SMARCA2 SMARCA4

1.52e-052136232855269
Pubmed

The Ran-binding protein RanBPM can depress the NF-κB pathway by interacting with TRAF6.

TRAF6 RANBP9

1.52e-052136221805090
Pubmed

Downregulation of SWI/SNF chromatin remodeling factor subunits modulates cisplatin cytotoxicity.

SMARCA2 SMARCA4

1.52e-052136222721696
Pubmed

Cloning of the human interferon-related developmental regulator (IFRD1) gene coding for the PC4 protein, a member of a novel family of developmentally regulated genes.

IFRD1 IFRD2

1.52e-05213629722946
Pubmed

Chromatin remodeling complexes interact dynamically with a glucocorticoid receptor-regulated promoter.

SMARCA2 SMARCA4

1.52e-052136218508913
Pubmed

Compensation of BRG-1 function by Brm: insight into the role of the core SWI-SNF subunits in retinoblastoma tumor suppressor signaling.

SMARCA2 SMARCA4

1.52e-052136211719516
Pubmed

DNA binding drives the association of BRG1/hBRM bromodomains with nucleosomes.

SMARCA2 SMARCA4

1.52e-052136228706277
Pubmed

[Expression of BRG1 and BRM proteins in prostatic cancer].

SMARCA2 SMARCA4

1.52e-052136221092585
InteractionUBC interactions

CCDC14 RABEP2 MYD88 USP34 UBR4 HECTD4 NVL RNF213 BRAP ITPR3 IKBKE ZNF451 USP4 HERC1 CAPN15

2.40e-0744613215int:UBC
InteractionUBE2L3 interactions

USP34 TRAF6 UBR4 MKRN2 HECTD4 RNF213 BRAP ZPR1 ARIH1 HERC1

1.31e-0621113210int:UBE2L3
InteractionUBE2D1 interactions

USP34 TRAF2 TRAF6 UVSSA MKRN2 TRIM24 ASB9 ZPR1 ARIH1 FBXL2 TRIM38

3.83e-0629413211int:UBE2D1
InteractionZIC2 interactions

MKRN2 CMSS1 SMARCA2 ARIH1 FBXW11

5.38e-06391325int:ZIC2
InteractionNR3C1 interactions

RABEP2 TRAF2 PLVAP IPO7 KDM5A UBR4 RANBP9 PPFIA3 CMSS1 NCLN ARID1A INTS3 TRIM24 RYR1 ITPR3 CEP350 SMARCA2 SMARCA4 CEP295 STAG2

5.42e-0697413220int:NR3C1
InteractionUBE2D2 interactions

TRAF2 TRAF6 UVSSA UBR4 MKRN2 HECTD4 RNF213 BRAP ZPR1 HERC1 TRIM38

8.07e-0631813211int:UBE2D2
InteractionTOP3B interactions

USP34 POLG UBR4 MKRN2 RTTN HECTD4 LMNB2 NCLN ARID1A ZZEF1 LDLR RYR1 ITPR3 CELSR2 PLA2G4B IFRD2 LRRC56 STK40 HERC1 HAS3 SIPA1L2 PUM1 DNA2 ABTB2 ARAP1

8.98e-06147013225int:TOP3B
InteractionIRF4 interactions

MYD88 TRAF2 TRAF6 ARID1A SMARCA2 USP4

2.02e-05851326int:IRF4
InteractionRNF123 interactions

CFAP47 HSPBAP1 MYO19 UBR4 RNF213 PBX4 NCBP1 LMNB2 AGPS PPFIA3 PARP14 ZZEF1 RYR1 MTHFD1 CEP295 TNR FBXO34

2.77e-0582413217int:RNF123
InteractionSPANXN3 interactions

PBX4 CMSS1 ARIH1 FBXW11

3.68e-05291324int:SPANXN3
InteractionKDM1A interactions

CCDC14 USP34 KDM5A UBR4 MKRN2 RANBP9 MSANTD2 PBX4 TRIM24 KIF20B SPDL1 CEP350 RLF KRT39 ZNF451 BUB1 SMARCA2 ARIH1

4.27e-0594113218int:KDM1A
InteractionSMG7 interactions

IPO7 UVSSA MKRN2 AGPS ARID1A TRIM24 PUM1 DNA2 ABTB2 FBXW11

4.87e-0531913210int:SMG7
InteractionBRCA1 interactions

CFAP47 GNL3L IPO7 UBR4 MKRN2 RANBP9 PRC1 ARID1A TRIM24 KIF20B BRAP CEP350 BLM MTHFD1 SMARCA2 SMARCA4 ARIH1 POLN HERC1 HSPA14 CDK4

6.14e-05124913221int:BRCA1
InteractionNANOG interactions

USP34 GNL3L NVL PRC1 ARID1A TRIM24 KIF20B ITPR3 SMARCA2 SMARCA4 SIPA1L2 PUM1

7.80e-0548113212int:NANOG
InteractionPPP2R1B interactions

USP53 NCBP1 PRC1 INTS3 DNAAF5 FBXW11 CDK4

8.61e-051591327int:PPP2R1B
InteractionSLX4 interactions

IPO7 PMPCB NVL TRIM24 SPDL1 CEP350 BLM MTHFD1 ZNF451 MCM9 SMARCA4 GID8 CORO7

9.98e-0557213213int:SLX4
InteractionKDM4B interactions

TRAF6 PARP14 SMARCA4 HSPA14 KDM4B

1.03e-04711325int:KDM4B
InteractionUBE2D3 interactions

TRAF2 TRAF6 UVSSA RNF213 ARIH1 HERC1 FBXL2 TRIM38 FBXW11

1.05e-042831329int:UBE2D3
InteractionH2BC8 interactions

GNL3L POLG NVL NCBP1 PRC1 INTS3 TRIM24 KIF20B BLM RLF SMARCA4 STAG2 KDM4B

1.07e-0457613213int:H2BC8
InteractionPLEC interactions

USP53 TRAF2 MYO19 TSGA10 PRC1 SPDL1 KRT39 ZNF451 BUB1 USP4 DNA2

1.26e-0443013211int:PLEC
InteractionSH2D3C interactions

USP34 TRAF2 ANXA3 RNF213 LDLR DNAAF5 ALDH1A3

1.41e-041721327int:SH2D3C
InteractionLMBR1L interactions

GNL3L IPO7 UBR4 LMNB2 CMSS1 NCLN PEX11B ITPR3 DNAAF5 IFRD1 LRIG1 CORO7 PUM1 HSPA14 STAG2 CAPN15 CDK4

1.51e-0494613217int:LMBR1L
Cytoband3q21.1

CCDC14 HSPBAP1 PARP14

2.79e-052013633q21.1
GeneFamilyRing finger proteins

TRAF2 TRAF6 MKRN2 RNF213 TRIM24 BRAP TRIM38

4.76e-0427591758
GeneFamilyTNF receptor associated factors

TRAF2 TRAF6

5.18e-0479121056
CoexpressionFISCHER_DREAM_TARGETS

CCDC14 USP53 TCEA1 LRRC45 MYO19 RTTN NCBP1 CMSS1 PRC1 LDLR KIF20B SPDL1 BLM IFRD1 MTHFD1 IFRD2 BUB1 CEP295 DNA2 THAP12 CDK4

2.59e-0896913521M149
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

USP34 IPO7 KDM5A NVL ZZEF1 TRIM24 LDLR KIF20B CEP350 BLM RLF IFRD1 LRIG1 ZNF451 SMARCA2 ARIH1 PUM1 STAG2 FBXW11

8.85e-0885613519M4500
CoexpressionBRUINS_UVC_RESPONSE_EARLY_LATE

TRAF2 ANXA3 UVSSA ARID1A INTS3 IFRD1 LRIG1 ARIH1 PUM1 STAG2 FBXW11

7.81e-0731613511M2248
CoexpressionBRUINS_UVC_RESPONSE_EARLY_LATE

TRAF2 ANXA3 UVSSA ARID1A INTS3 IFRD1 LRIG1 ARIH1 PUM1 STAG2 FBXW11

8.83e-0732013511MM1063
CoexpressionGSE21546_WT_VS_SAP1A_KO_ANTI_CD3_STIM_DP_THYMOCYTES_DN

RABEP2 USP34 PARP8 ODF1 PARP14 METAP1 IKBKE MCM9 KDM4B

9.99e-072001359M7532
CoexpressionHE_LIM_SUN_FETAL_LUNG_C2_CYCLING_DC_CELL

CCDC14 RABEP2 TRAF2 LRRC45 MYO19 MKRN2 NVL NCBP1 LMNB2 AGPS CMSS1 PRC1 CCNQ KIF20B SPDL1 BLM METAP1 MTHFD1 IFRD2 BUB1 CEP295 DNA2

3.65e-06142313522M45722
CoexpressionLIU_SOX4_TARGETS_DN

USP34 GNL3L HECTD4 ATP9B ITPR3 SMARCA2 SMARCA4 PUM1 STAG2 CAPN15

4.96e-0631013510M17287
CoexpressionHE_LIM_SUN_FETAL_LUNG_C4_CYCLING_T_CELL

CCDC14 TRAF2 LRRC45 MYO19 LMNB2 CMSS1 PRC1 LDLR KIF20B BRAP SPDL1 BLM MTHFD1 BUB1 SMARCA4 CEP295 DNA2

6.99e-0693913517M45768
CoexpressionGSE22886_UNSTIM_VS_IL15_STIM_NKCELL_DN

IPO7 LMNB2 PRC1 LDLR BLM MTHFD1 HSPA14 CDK4

9.67e-062001358M4533
CoexpressionGSE22886_UNSTIM_VS_IL2_STIM_NKCELL_DN

IPO7 LMNB2 PRC1 LDLR BLM MTHFD1 IFRD2 CDK4

9.67e-062001358M4531
CoexpressionHE_LIM_SUN_FETAL_LUNG_C4_CYCLING_NK_CELL

CCDC14 TRAF2 LRRC45 RANBP9 LMNB2 PRC1 TRIM24 KIF20B SPDL1 BLM MTHFD1 BUB1 CEP295 DNA2

1.46e-0569413514M45767
CoexpressionGEORGES_TARGETS_OF_MIR192_AND_MIR215

CCDC14 USP34 HSPBAP1 NCBP1 ERMP1 LMNB2 KIF20B BLM IFRD1 LRIG1 ZDHHC23 MCM9 SMARCA2 GID8 CEP295 HAS3

1.49e-0589213516M18120
CoexpressionHE_LIM_SUN_FETAL_LUNG_C6_DEUTEROSOMAL_CELL

CCDC14 RTTN PRC1 KIF20B BUB1 CEP295 CCDC171 CCDC158

1.99e-052211358M45789
CoexpressionDANG_BOUND_BY_MYC

KDM5A PMPCB NCBP1 AGPS PEX11B KIF20B BLM MTHFD1 ZPR1 ZNF451 IFRD2 BUB1 USP4 HERC1 THAP12 HSPA14 CDK4

3.34e-05106113517M15774
CoexpressionPUJANA_CHEK2_PCC_NETWORK

TCEA1 MYO1A POLG NCBP1 LMNB2 TRIM24 KIF20B BLM METAP1 BUB1 SMARCA4 DNA2 THAP12 CDK4

4.00e-0576113514M11961
CoexpressionDUTERTRE_ESTRADIOL_RESPONSE_24HR_UP

MYO19 PRC1 SPDL1 BLM CELSR2 LRIG1 MTHFD1 BUB1 DNA2

4.71e-053231359M2156
CoexpressionHE_LIM_SUN_FETAL_LUNG_C5_LARGE_PRE_B_CELL

CCDC14 TRAF2 IPO7 LRRC45 NCBP1 LMNB2 AGPS CMSS1 PRC1 TRIM24 KIF20B SPDL1 BLM MTHFD1 IFRD2 BUB1 CEP295 DNA2 CDK4

7.35e-05136313519M45782
CoexpressionGSE37532_TREG_VS_TCONV_PPARG_KO_CD4_TCELL_FROM_LN_DN

MYD88 CMSS1 NCLN DNAH1 DNAAF5 IFRD2 ABTB2

7.98e-051991357M8960
CoexpressionGSE22432_CONVENTIONAL_CDC_VS_PLASMACYTOID_PDC_DN

RABEP2 TRAF2 PARP8 PARP14 ZPR1 STK40 KDM4B

8.23e-052001357M7814
CoexpressionGSE11864_CSF1_IFNG_VS_CSF1_PAM3CYS_IN_MAC_UP

MYD88 HSPBAP1 ERMP1 INTS3 SMARCA2 SIGLEC1 FRMD3

8.23e-052001357M3142
CoexpressionDODD_NASOPHARYNGEAL_CARCINOMA_UP

CCDC14 MYO19 RNF213 NCBP1 LMNB2 CMSS1 PRC1 TRIM24 KIF20B BRAP SPDL1 IFRD1 ASB9 BUB1 SMARCA4 SIGLEC1 DNA2 HSPA14 CDK4

1.12e-04140713519M14427
CoexpressionKINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP

TCEA1 IPO7 MYO19 MKRN2 RTTN RANBP9 NCBP1 PRC1 KIF20B SPDL1 ITPR3 BLM DNAAF5 IFRD1 MTHFD1 ZPR1 BUB1 DNA2

1.14e-04129013518M80
CoexpressionNADERI_BREAST_CANCER_PROGNOSIS_UP

TRIM24 BUB1 SMARCA4 HSPA14

1.39e-04511354M6862
CoexpressionBASAKI_YBX1_TARGETS_UP

ANXA3 MYO19 LMNB2 PRC1 SPDL1 MTHFD1 IFRD2 BUB1

1.47e-042941358M14985
CoexpressionHAMAI_APOPTOSIS_VIA_TRAIL_UP

TCEA1 ZBTB38 ZNF397 TRIM24 KIF20B SPDL1 CEP350 BLM RLF PIEZO2 SMARCA2 STAG2

1.54e-0465613512M18979
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN

IPO7 KDM5A NVL KIF20B CEP350 BLM SMARCA2 ARIH1 PUM1 FBXW11

1.56e-0446613510M13522
CoexpressionBENPORATH_MYC_MAX_TARGETS

KDM5A PMPCB NCBP1 AGPS PEX11B TRIM24 KIF20B MTHFD1 ZPR1 USP4 HERC1 THAP12 HSPA14

1.90e-0477513513M17753
ToppCellPSB-critical-LOC-Epithelial-FOXN4+|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CCDC14 RTTN RANBP9 PRC1 KIF20B BLM BUB1 CEP295 CCDC171

8.54e-091931369b7d9c5bed524423e92f01496a9f8fad11b33a3f7
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC14 CFAP47 RANBP9 SPACA9 BUB1 CCDC171 CCDC158 CFAP46

8.54e-0818013680c146e80d55d18b6988dd21b1da635801bd3140c
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC14 CFAP47 RANBP9 SPACA9 BUB1 CCDC171 CCDC158 CFAP46

8.54e-081801368e9af22beae2f3c7fe213b4e19df84abfd2453433
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC14 CFAP47 RANBP9 SPACA9 BUB1 CCDC171 CCDC158 CFAP46

8.54e-08180136811455ba704ac73f69b474845136cfecec6a88349
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

USP34 RNF213 PARP14 LDLR RLF IFRD1 ARIH1 HERC1

1.19e-071881368ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellNS-critical-d_07-13-Epithelial-FOXN4+|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CCDC14 RTTN KIF20B ITPR3 LRIG1 BUB1 CEP295 CCDC171

1.29e-0719013687be0f2ff86ca8500a43e0d44e5e292530f9ba0bb
ToppCellmoderate-Epithelial-FOXN4+|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CCDC14 RTTN RANBP9 KIF20B CEP350 BUB1 CEP295 CCDC171

1.52e-071941368dff3fb10372053951d41e0ccd41aac3ece6009bd
ToppCellcritical-Epithelial-FOXN4+|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CCDC14 RTTN KIF20B CEP350 BLM BUB1 CEP295 CCDC171

1.92e-072001368f39db4250ce220a3eb58edee3f7fc3671701d46f
ToppCellPND07-28-samps-Epithelial-Epithelial-non_alveolar-Ciliated_cell_of_lung_parenchyma|PND07-28-samps / Age Group, Lineage, Cell class and subclass

CFAP47 SPACA9 NME9 AK7 DNAH1 ZDHHC23 CFAP46

1.10e-061741367f41d05a3703d7092bd3c4a97c15ae13069aaa4ad
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA13 SPACA9 AK7 DNAH1 WDR97 LRRC56 CFAP46

1.28e-0617813673b12db04006db6e94fc45649a4b3a63b92f21a61
ToppCell15-Trachea-Epithelial-Multiciliated_precursor|Trachea / Age, Tissue, Lineage and Cell class

CCDC14 RTTN RANBP9 SPACA9 CEP350 CCDC171 CFAP46

1.66e-0618513679a8b8360d99375b726ca8e3c9a3f9b08919892d7
ToppCellTCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Cervical_Squamous_Cell_Carcinoma-3|TCGA-Cervix / Sample_Type by Project: Shred V9

POLG UBR4 ERMP1 CEP350 HERC1 ARAP1

2.07e-0612213661ed865f0ecfe304fb86313ff51c04e9052357270
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

RNF213 PBX4 ATP9B LDLR IFRD1 ARIH1 HERC1

2.12e-06192136747646d7e4990be85072987f92bf18d52f8da752e
ToppCellhuman_hepatoblastoma-Tumor_cells-T1|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

RTTN CMSS1 KIF20B BLM BUB1 CEP295 DNA2

2.19e-0619313674b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_cycling|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

LMNB2 PRC1 KIF20B SPDL1 BLM BUB1 DNA2

2.35e-061951367926eb3fc5d028be936885bea0654a77db3107234
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_cycling|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

LMNB2 PRC1 KIF20B SPDL1 BLM BUB1 DNA2

2.43e-06196136773f951f7712e0aa3323676b9a4b7944d21d347c4
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

USP34 PARP8 RTTN RNF213 PARP14 ZNF451 HERC1

2.69e-061991367f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

POLG CNBD2 PRC1 SPDL1 BUB1 FRMD3

8.24e-0615513668e239470799426ea474a36f57e1b7e0d9365ca5f
ToppCellNS-moderate-d_07-13-Epithelial-FOXN4+|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFAP47 RTTN ZDHHC23 CEP295 CCDC171 CFAP46

8.87e-061571366410c9d74a2085179cfb39853cb6d330fa98c9c1b
ToppCell3'_v3-GI_small-bowel-Lymphocytic_T_CD8-Tem/emra_CD8|GI_small-bowel / Manually curated celltypes from each tissue

NPR3 PLVAP ANXA3 ASB9 ALDH1A3 NOS3

1.10e-0516313661a8c79903ed416f286ebe8a9922233affbc55d82
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KIF20B SPDL1 BLM BUB1 CEP295 DNA2

1.35e-051691366b253a4a50c06d36228fcd5d856c57202cbac158f
ToppCellPND01-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYO19 PRC1 KIF20B SPDL1 BUB1 DNA2

1.44e-0517113666e7ade1d14a3ec4c566476aac3eb509bd2661e39
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

PARP8 RNF213 PBX4 LDLR ARIH1 HERC1

1.44e-0517113662e9a20f8980b78325c52065a9c14ab3656267c05
ToppCellwk_20-22-Epithelial-Proximal_epithelial-Deuterosomal|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

CFAP47 TSGA10 SPACA9 CCDC171 CCDC158 CFAP46

1.44e-05171136652aec5f6677fe2f7a36fb5b18117a4cffaeff58f
ToppCellLymphoid-Lymphoid-B_cells_(cycle)|Lymphoid / shred on cell class and cell subclass (v4)

PBX4 PRC1 LDLR RYR1 SPDL1 MCM9

1.49e-051721366f39822afcc35f0fbf68b8ffd1894e4b6c8d7a80c
ToppCellPND07-28-samps-Epithelial-Epithelial-non_alveolar|PND07-28-samps / Age Group, Lineage, Cell class and subclass

CFAP47 NME9 AK7 DNAH1 ZDHHC23 CFAP46

1.64e-051751366c01a15b2084da4a18f8ff3623f44eb9dfe499f10
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LMNB2 PRC1 KIF20B SPDL1 BUB1 ALDH1A3

1.75e-0517713664197cf2b1e743230c821f422836fa5991b155a52
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PLVAP LMNB2 PRC1 PIEZO2 BUB1 NOS3

1.75e-05177136673ba0f0b4b33f10e9f036d6d9befa48a1258e682
ToppCelldroplet-Heart-4Chambers-21m-Mesenchymal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC14 MKRN2 DNAH1 BLM PTPRD LRIG1

1.87e-051791366b44e2d53b82c3c141bfc6539054b19708200a0d9
ToppCell10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8|Liver / Manually curated celltypes from each tissue

USP34 PARP8 RNF213 PBX4 LRIG1 HERC1

1.99e-051811366f2315414e714ac86211546a935660c4be6e85f1b
ToppCellPBMC-Control-cDC_12|Control / Compartment, Disease Groups and Clusters

TRAF2 ANXA3 MYO19 BLM METAP1 DNA2

2.05e-0518213664774066d0f9986abc3d13a2a3bc99ce4f1327ae0
ToppCellwk_15-18-Epithelial-Proximal_epithelial-Deuterosomal|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CFAP47 TSGA10 SPACA9 AK7 CCDC158 CFAP46

2.05e-051821366000eca5baa6eb2335a1e6d76a13fff5382b0e150
ToppCell21-Trachea-Epithelial-Multiciliated_precursor|Trachea / Age, Tissue, Lineage and Cell class

CFAP47 RANBP9 SPACA9 ZDHHC23 CCDC171 CFAP46

2.05e-0518213666e35892fa959ee31591850ded8f1088195ddeb01
ToppCellControl-T_cells-Cycling_NK/T_cells|Control / group, cell type (main and fine annotations)

LMNB2 PRC1 KIF20B BLM BUB1 DNA2

2.25e-0518513669766216b41ee62bbac4caa25cb98ec5627a24075
ToppCellAdult-Epithelial-ciliated_cell-D175|Adult / Lineage, Cell type, age group and donor

CFAP47 TSGA10 UROC1 NME9 AK7 CFAP46

2.25e-05185136630f4980dee6cd5959655f8d74049f3bfb5312611
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA3 LMNB2 KIF20B BLM BUB1 DNA2

2.39e-0518713669351fa87b69a951af85b10bf91fe9b1cce8c0517
ToppCellNS-moderate-d_16-33-Epithelial-FOXN4+|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CCDC14 RTTN BUB1 CEP295 CCDC171 CFAP46

2.61e-051901366250ca4a605c1cccd77d23383e4fe6f91cf3609ba
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

RNF213 PARP14 LDLR ZDHHC23 MCM9 DNA2

2.69e-0519113669454f642c3621370fa23640b631301346b300950
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

LMNB2 PRC1 KIF20B SPDL1 BUB1 DNA2

2.77e-05192136627723f4e320e49d4a3daafa2d8d3946ff79fab64
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

LMNB2 PRC1 KIF20B SPDL1 BUB1 DNA2

2.77e-0519213660a54c79dcfdeb99e3b512d42b22359618cfd17e9
ToppCellfacs-Aorta-Heart-3m|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPR3 UBR4 LAMA3 CEP350 PIEZO2 CCNI

2.77e-0519213661ccc47792edf9ee23501c8e2165d11271636b66a
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

USP34 GNL3L ARID1A CEP350 PUM1 STAG2

2.85e-051931366abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

LMNB2 PRC1 KIF20B BLM BUB1 DNA2

2.94e-051941366f9070035553bc68106a9e0bdf4b507715a138aba
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 ANXA3 LAMA3 RNF213 ITPR3 FBXL2

2.94e-051941366e577d9e88390b36b5a09b97fe1026089892275a3
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP47 ABCA13 TSGA10 SPACA9 AK7 CFAP46

2.94e-0519413664a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

RTTN KIF20B BLM MTHFD1 DNA2 CDK4

3.02e-051951366cec7df321f372d05c94f97d6bb18891a5cc3dec3
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MYO19 RTTN KIF20B BLM MTHFD1 DNA2

3.02e-051951366b65463a804fed2d9a3be9e528ca8b9c98469bc86
ToppCellControl-Lymphoid-T|Lymphoid / Disease state, Lineage and Cell class

CASS4 PARP8 PBX4 LDLR LRIG1 SMARCA2

3.02e-0519513666687e579582d7a239bee80846de0cf827a6f6a62
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

LMNB2 PRC1 KIF20B BLM BUB1 DNA2

3.02e-0519513661a5e814e12fe37287dbfc58189e1958e2c76b5da
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

MYO19 RTTN KIF20B BLM MTHFD1 DNA2

3.02e-05195136656d8734d020b3da08a5aa9e67999706a9e023a99
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PLVAP LMNB2 PRC1 KIF20B SPDL1 BUB1

3.11e-05196136620383d576708b7e4bfce3e9fe40548cce496e3cb
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

LMNB2 PRC1 KIF20B BLM BUB1 DNA2

3.11e-0519613661d2e0b328eb822db7521b5f5724d4bd17c0bad5f
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

LMNB2 PRC1 KIF20B BLM BUB1 DNA2

3.11e-0519613661964c5003a0cb84539850a7cfe3bbb0e23a61d2d
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PLVAP LMNB2 PRC1 KIF20B SPDL1 BUB1

3.11e-0519613660644bd14a944b9c9759a295dfdd5e67a4775f20a
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

LMNB2 PRC1 KIF20B BLM BUB1 DNA2

3.20e-05197136684ed777cdba569200a3ef1654d8a12f17fcfb7f1
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_cycling|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

LMNB2 PRC1 KIF20B BLM BUB1 DNA2

3.20e-0519713668b616cde333bdbc0c591035ad9e4949155866245
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PLVAP PRC1 KIF20B SPDL1 BUB1 CEP295

3.20e-0519713661c89d6836eed30c50c765f7dde9cc8ee15c363d2
ToppCell(11)_FOXN4+|World / shred by cell type by condition

CCDC14 ODF1 KIF20B BLM BUB1 CCDC171

3.29e-051981366516b1acdf997dd8debc3dca066519366e507b414
ToppCell(03)_KRT6B+-(2)_GFP_FOXI1|(03)_KRT6B+ / shred by cell type by condition

USP53 TCEA1 CEP350 SMARCA2 TRIM38 STAG2

3.39e-051991366c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCellTransverse-Dendritic_cell-cycling_DCs|Dendritic_cell / Region, Cell class and subclass

CCDC14 LMNB2 PRC1 KIF20B SPDL1 BUB1

3.48e-052001366617a6a42f7b31eb3c45bdceaf55a591b6de7f154
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P5-P5_1-Sox4-POLYDENDROCYTE_(Neurogenesis.Sox4.Cdc20)|Hippocampus / BrainAtlas - Mouse McCarroll V32

MYO1A PRC1 KIF20B SPDL1 BUB1

5.14e-051311365f9fb8d74ca720b81fd5910cc975510359a8ef751
ToppCellPND01-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PRC1 KIF20B SPDL1 BUB1 DNA2

7.54e-051421365be63c48794a227ea55978524c0f5935342fc455e
ToppCell10x5'-Lung-Lymphocytic_T_CD4-T_CD4/CD8|Lung / Manually curated celltypes from each tissue

CFAP47 ABCA13 PARP8 PBX4 CFAP46

1.17e-04156136510d191e29b16cae8238e8df6c0ff38882253f34e
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c02-AQP3|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CASS4 NVL AGPS PRC1 CEP350

1.28e-041591365ba82d1f55dd77c4b2183981b76cab1480fba75ad
ToppCelldroplet-Lung-3m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l15|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PMPCB PPFIA4 BLM CEP295 DNA2

1.53e-0416513651d0f60bf47a40ac916f0fcb5532a968742a0edbb
ToppCelldroplet-Heart-nan-24m-Hematologic-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRC1 KIF20B BLM CELSR2 POLN

1.61e-041671365bad33497ceeab968a7eb8a48b921c6f936390743
ToppCellPND14-Immune-Immune_Myeloid-DC-cDC2-cDC2_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PPFIA4 PRC1 KIF20B SPDL1 BLM

1.66e-041681365b7cd33f5da4f37b9384fc3bd3ca01fbc790accfc
ToppCell368C-Fibroblasts-Fibroblast-C_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

PLVAP ANXA3 CEP350 BUB1 FRMD3

1.66e-041681365c66a61d3ec711796313a2c6d2dc39aedbfc20afd
ToppCell368C-Fibroblasts-Fibroblast-C_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

PLVAP ANXA3 CEP350 BUB1 FRMD3

1.66e-04168136583b4f817d95daa15ae60668e789f97d8a3b2e6dd
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PRC1 KIF20B SPDL1 PTPRD BUB1

1.71e-041691365563c267edaade0e5df192ad953801ef9768d4270
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Mesenchymal-ependymal_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPACA9 NME9 AK7 DNAH1 CFAP46

1.75e-041701365b535baeb4dbd644051cf992babb61add9eaae4e3
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PBX4 PRC1 KIF20B BLM BUB1

1.75e-041701365b04e2f84024baaae9b4ff19bdac8c69afdb92a76
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Mesenchymal-Ependyma|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPACA9 NME9 AK7 DNAH1 CFAP46

1.75e-0417013652477c9f29dbe27f172df699003971e828d6ab8c9
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(15)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

LMNB2 PRC1 KIF20B SPDL1 BUB1

1.85e-0417213657f3d0ef18f5df1ed80498d435b0378ca398c0b88
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LMNB2 PRC1 KIF20B BUB1 POLN

1.85e-041721365c06ca5d075937747952ed915c9db39a9f62072f9
ToppCell368C-Endothelial_cells-Endothelial-B_(Artery)-|368C / Donor, Lineage, Cell class and subclass (all cells)

NPR3 PLVAP ANXA3 PPFIA3 NOS3

1.90e-041731365ec88e871b49331fca59bc610a8ae58e2d5e76bc1
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_prolif|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TRAF2 NPR3 PLVAP LMNB2 TNR

1.90e-04173136512f779b8dce79431b2d1002ba524dd3f9566aeb0
ToppCell368C-Endothelial_cells-Endothelial-B_(Artery)|368C / Donor, Lineage, Cell class and subclass (all cells)

NPR3 PLVAP ANXA3 PPFIA3 NOS3

1.90e-04173136522200fe74e33e2beae0eed289ca8476bbc0b1b2d
ToppCellCV-Mild-7|Mild / Virus stimulation, Condition and Cluster

TRAF6 AGPS ZDHHC23 ABTB2 FBXW11

1.90e-041731365c9bbca9313a0fdf146c8c995624b94b937e818d8
ToppCellTCGA-Adrenal-Primary_Tumor-Adrenocortical_carcinoma-Usual_Type-4|TCGA-Adrenal / Sample_Type by Project: Shred V9

NCLN TRIM24 LDLR FARP1 KDM4B

1.95e-04174136515e2b9f46404ff9575e149024b24cb17b50b02b5
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LMNB2 PRC1 KIF20B BLM BUB1

1.95e-04174136572df66319f6efbd88ecf439013d97409fbf3cb52
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LMNB2 PRC1 KIF20B BLM BUB1

1.95e-041741365c6087fd0e036ec7f40f0f8f17d1f6ce13ddb5235
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LMNB2 PRC1 KIF20B BLM BUB1

1.95e-041741365dbb4e1a6c3319ce40f81bfd2d1745a88a2cc412e
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC14 RANBP9 SPACA9 BUB1 CCDC171

1.95e-0417413650227fea1678baa9168bd47c3b4aacb2592bb5867
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PPFIA3 PRC1 KIF20B BUB1 CEP295

1.95e-0417413657b2f35add804981c7d588a996bdbca6ec11a1ca5
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC14 RANBP9 SPACA9 BUB1 CCDC171

1.95e-041741365c2f8c59fca5f1ff6ffa6dc8cfce62da4b19fe9b3
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC14 RANBP9 SPACA9 BUB1 CCDC171

1.95e-04174136584024c04b0ce9f7068677d2d99ede56882b7dbd2
ToppCellClub-club-15|World / Class top

PRC1 INTS3 SPDL1 USP4 ALDH1A3

2.01e-041751365ca9d012f520f697c7450ec6958a015e20538a6a8
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Granulocytic-Neutrophil-Neu_c4-RSAD2|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RNF213 PARP14 INTS3 TRIM38 FRMD3

2.01e-04175136597616bb5c127284aa9e67bc336dfcf29e137164b
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PLVAP PRC1 KIF20B BUB1 NOS3

2.01e-041751365d43ae33a6256606ce848247cad32d74f21b38988
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l7|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PLVAP PARP14 UNC45B HAS3 NOS3

2.01e-0417513657be76d39e1a4f4ac709672cd2d409a2523a083ce
ToppCell3'_v3-Lung-Lymphocytic_T_CD4/8-lo-Cycling_T|Lung / Manually curated celltypes from each tissue

ODF1 PRC1 KIF20B BUB1 DNA2

2.06e-041761365a40dfd8c4ba16757ff929b2f03a0628acf334de4
ToppCellPND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP47 PBX4 AK7 CCDC171 CFAP46

2.06e-041761365d6d7e4e937d49a5c0d16322c8dd3bf9e97eb8732
ToppCellPND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP47 PBX4 AK7 CCDC171 CFAP46

2.06e-041761365c03d80df2550c0d2b0452326480d6bf21d20fdd2
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP47 NME9 AK7 DNAH1 CCDC158

2.11e-041771365e8bb4f8ecd5e283efec966b9fc2040a6152d5551
ToppCellfacs-Trachea-3m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell-ciliated_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CFAP47 SPACA9 NME9 AK7 CFAP46

2.11e-0417713653cfde67b93f3986312f5e74e42504214d966e7dc
ToppCellfacs-Trachea-3m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CFAP47 SPACA9 NME9 AK7 CFAP46

2.11e-04177136512a52a12a87a31e501ced611f46a90d172ca7e35
ToppCellfacs-Marrow-Granulocytes-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA13 ANXA3 PRC1 KIF20B BUB1

2.17e-04178136515a99080e9f669572ab6d82934f324e6714846c1
ToppCell10x5'v1-week_17-19-Hematopoietic-HSC/MPP_and_pro-MEP|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

NPR3 PPFIA3 PIEZO2 ASB9 SMARCA2

2.17e-041781365b8c301d65c0f37941e8e9414d55e90edb6ecc195
ToppCellfacs-Marrow-Granulocytes-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA13 ANXA3 PRC1 KIF20B BUB1

2.17e-041781365200308e109abb7e6f8816a6f8cce6d56862d4098
DrugCamptothecine (S,+) [7689-03-4]; Down 200; 11.4uM; PC3; HT_HG-U133A

HSPBAP1 ARID1A TRIM24 LDLR CEP350 RLF IFRD1 PUM1 FBXO34

1.40e-0618013694541_DN
DrugCamptothecine (S,+) [7689-03-4]; Down 200; 11.4uM; MCF7; HT_HG-U133A

ARID1A TRIM24 LDLR KIF20B CEP350 RLF IFRD1 PUM1 FBXW11

1.53e-0618213693887_DN
DiseaseMENTAL RETARDATION, AUTOSOMAL DOMINANT 12

ARID1A SMARCA2 SMARCA4

8.89e-0751333C3281201
Diseasevery low density lipoprotein cholesterol measurement, esterified cholesterol measurement

PBX4 CELSR2 ZPR1 SMARCA4

1.15e-06181334EFO_0008317, EFO_0008589
Diseasesodium-coupled monocarboxylate transporter 1 measurement

LDLR CELSR2 ZPR1 SMARCA4

1.45e-06191334EFO_0802076
Diseaselarge artery stroke, coronary artery disease

BRAP CELSR2 ZPR1 SMARCA4

4.64e-06251334EFO_0001645, EFO_0005524
DiseaseAntithrombotic agent use measurement

HECTD4 LDLR CELSR2 ZPR1 SMARCA4

5.01e-06551335EFO_0009925
Diseasefamilial hyperlipidemia

PBX4 ARID1A LDLR CELSR2 ZPR1 SMARCA4

8.83e-061061336MONDO_0001336
DiseaseAbnormal circulating lipid concentration

LDLR SMARCA4

2.02e-0521332HP_0003119
DiseaseCoffin-Siris syndrome

ARID1A SMARCA2 SMARCA4

2.48e-05131333C0265338
DiseaseHMG CoA reductase inhibitor use measurement

ARID1A LDLR ITPR3 CELSR2 ZPR1 SMARCA4 NOS3

2.49e-051891337EFO_0009932
Diseaseaspirin use measurement

LDLR CELSR2 ZPR1 SMARCA4

2.87e-05391334EFO_0007013
Diseaseesterified cholesterol measurement, low density lipoprotein cholesterol measurement

LDLR CELSR2 SMARCA4

3.14e-05141333EFO_0004611, EFO_0008589
Diseaselipoprotein-associated phospholipase A(2) measurement

RNF213 LDLR CELSR2 ZPR1

3.18e-05401334EFO_0004746
Diseasefree cholesterol to total lipids in very small VLDL percentage

LDLR CELSR2 ZPR1 SMARCA4

4.25e-05431334EFO_0022290
Diseaseconcentration of large LDL particles measurement

LDLR CELSR2 ZPR1 SMARCA4

4.66e-05441334EFO_0022160
Diseasecholesterol in medium VLDL measurement

LDLR CELSR2 ZPR1 SMARCA4

4.66e-05441334EFO_0022225
Diseasetotal lipids in very small VLDL measurement

LDLR CELSR2 ZPR1 SMARCA4

5.09e-05451334EFO_0022156
Diseasecholesterol to total lipids in large VLDL percentage

LDLR CELSR2 ZPR1 SMARCA4

5.09e-05451334EFO_0022236
Diseaseprotocadherin alpha-4 measurement

ODF1 SIGLEC1

6.03e-0531332EFO_0801972
DiseaseBloom syndrome (implicated_via_orthology)

BLM DNA2

6.03e-0531332DOID:2717 (implicated_via_orthology)
DiseaseAbruptio Placentae

MTHFD1 NOS3

6.03e-0531332C0000832
Diseasetotal lipids in small LDL

LDLR CELSR2 ZPR1 SMARCA4

6.05e-05471334EFO_0022168
Diseasefree cholesterol in small VLDL measurement

LDLR CELSR2 ZPR1 SMARCA4

6.05e-05471334EFO_0022272
Diseasefree cholesterol in very small VLDL measurement

LDLR CELSR2 ZPR1 SMARCA4

6.05e-05471334EFO_0022275
Diseasefree cholesterol in medium VLDL measurement

LDLR CELSR2 ZPR1 SMARCA4

6.05e-05471334EFO_0022269
Diseasetotal lipids in lipoprotein particles measurement

LDLR CELSR2 ZPR1 SMARCA4

6.58e-05481334EFO_0022309
Diseasephospholipids in medium LDL measurement

LDLR CELSR2 ZPR1 SMARCA4

7.14e-05491334EFO_0022183
Diseasecholesterol in medium LDL measurement

LDLR CELSR2 ZPR1 SMARCA4

7.14e-05491334EFO_0022224
Diseasecholesterol in small LDL measurement

LDLR CELSR2 ZPR1 SMARCA4

7.14e-05491334EFO_0022227
Diseasecholesteryl esters to total lipids in small VLDL percentage

LDLR CELSR2 ZPR1 SMARCA4

7.14e-05491334EFO_0022256
Diseasetriglyceride measurement, very low density lipoprotein cholesterol measurement

PBX4 ARID1A LDLR DNAH1 CELSR2 ZPR1 SMARCA4

7.32e-052241337EFO_0004530, EFO_0008317
Diseasetriglycerides to total lipids in medium LDL percentage

LDLR CELSR2 ZPR1 SMARCA4

7.74e-05501334EFO_0022334
Diseasetriglycerides to total lipids in large LDL percentage

LDLR CELSR2 ZPR1 SMARCA4

8.37e-05511334EFO_0022331
Diseasephospholipids in very small VLDL measurement

LDLR CELSR2 ZPR1 SMARCA4

8.37e-05511334EFO_0022300
Diseasecholesterol to total lipids in small VLDL percentage

LDLR CELSR2 ZPR1 SMARCA4

8.37e-05511334EFO_0022242
Diseaseparental longevity

HECTD4 LMNB2 LDLR BRAP CEP350 PTPRD CELSR2 SMARCA2 SMARCA4 CCDC171

8.50e-0549413310EFO_0007796
Diseasephospholipids in medium VLDL measurement

LDLR CELSR2 ZPR1 SMARCA4

9.03e-05521334EFO_0022154
Diseasetotal lipids in medium LDL

LDLR CELSR2 ZPR1 SMARCA4

9.03e-05521334EFO_0022180
Diseasetriglycerides to total lipids in very large VLDL percentage

LDLR CELSR2 ZPR1 SMARCA4

9.73e-05531334EFO_0022340
Diseasecholesterol in small VLDL measurement

LDLR CELSR2 ZPR1 SMARCA4

9.73e-05531334EFO_0022228
Diseasecholesterol to total lipids in very large VLDL percentage

LDLR CELSR2 ZPR1 SMARCA4

1.05e-04541334EFO_0022244
Diseasestroke, coronary artery disease

BRAP CELSR2 SMARCA4

1.12e-04211333EFO_0000712, EFO_0001645
Diseasecholesteryl esters to total lipids in chylomicrons and extremely large VLDL percentage

LDLR CELSR2 SMARCA4

1.12e-04211333EFO_0022246
DiseaseFlushing

HECTD4 BRAP

1.20e-0441332HP_0031284
Diseasecholesterol to total lipids in large LDL percentage

LDLR CELSR2 ZPR1 SMARCA4

1.21e-04561334EFO_0022235
Diseasefree cholesterol to total lipids in large HDL percentage

LDLR CELSR2 ZPR1 SMARCA4

1.21e-04561334EFO_0022279
Diseasecholesteryl esters to total lipids in large VLDL percentage

LDLR CELSR2 ZPR1 SMARCA4

1.21e-04561334EFO_0022250
Diseasefree cholesterol to total lipids in medium VLDL percentage

LDLR CELSR2 ZPR1 SMARCA4

1.29e-04571334EFO_0022284
Diseaselow density lipoprotein particle size measurement

LDLR CELSR2 ZPR1 SMARCA4

1.39e-04581334EFO_0008593
Diseasetriglycerides to total lipids in small VLDL percentage

LDLR CELSR2 ZPR1 SMARCA4

1.39e-04581334EFO_0022338
DiseaseAgents acting on the renin-angiotensin system use measurement

NPR3 NME9 ARID1A LDLR CELSR2 ZPR1 SMARCA4 NOS3

1.45e-043351338EFO_0009931
Diseasefree cholesterol to total lipids in very large VLDL percentage

LDLR CELSR2 ZPR1 SMARCA4

1.48e-04591334EFO_0022289
Diseaseclinical and behavioural ideal cardiovascular health

LDLR CELSR2 SMARCA4

1.48e-04231333EFO_0007654
Diseasephospholipids in small VLDL measurement

LDLR CELSR2 ZPR1 SMARCA4

1.58e-04601334EFO_0022146
Diseasetotal lipids in VLDL measurement

ARID1A LDLR CELSR2 ZPR1

1.58e-04601334EFO_0022314
Diseaseantihyperlipidemic drug use measurement

ARID1A LDLR CELSR2 ZPR1 SMARCA4

1.78e-041151335EFO_0803367
Diseasetriglycerides in medium LDL measurement

ARID1A LDLR CELSR2 ZPR1

1.80e-04621334EFO_0022322
Diseasefree cholesterol in very large HDL measurement

LDLR CELSR2 ZPR1 SMARCA4

1.80e-04621334EFO_0022273
Diseasetriglycerides to total lipids in medium VLDL percentage

LDLR CELSR2 ZPR1 SMARCA4

1.91e-04631334EFO_0022335
Diseasecholesterol to total lipids in medium VLDL percentage

LDLR CELSR2 ZPR1 SMARCA4

1.91e-04631334EFO_0022239
Diseasemyocardial infarction

HECTD4 LMNB2 LDLR BRAP CELSR2 ZPR1 SMARCA4 NOS3

1.96e-043501338EFO_0000612
DiseaseWerner syndrome (implicated_via_orthology)

BLM DNA2

2.00e-0451332DOID:5688 (implicated_via_orthology)
Diseasevon Willebrand factor measurement, coronary artery disease

PMPCB HECTD4 CELSR2 SMARCA4 NOS3

2.01e-041181335EFO_0001645, EFO_0004629
Diseaseglycerol measurement

NPR3 SMARCA2 SIPA1L2

2.16e-04261333EFO_0010115
Diseaselevel of Sterol ester (27:1/18:2) in blood serum

LDLR ZPR1 SMARCA4

2.16e-04261333OBA_2045194
DiseaseCoronary Arteriosclerosis

TRAF6 HECTD4 LDLR NOS3

2.16e-04651334C0010054
Diseasecholesterol in large VLDL measurement

ARID1A LDLR CELSR2 ZPR1

2.16e-04651334EFO_0021902
Diseasecholesterol in very large VLDL measurement

ARID1A LDLR CELSR2 ZPR1

2.16e-04651334EFO_0022230
DiseaseCoronary Artery Disease

TRAF6 HECTD4 LDLR NOS3

2.16e-04651334C1956346
Diseaselow density lipoprotein cholesterol measurement, phospholipid measurement

LDLR CELSR2 ZPR1 CEACAM16 SMARCA4

2.17e-041201335EFO_0004611, EFO_0004639
Diseasefree cholesterol in large VLDL measurement

ARID1A LDLR CELSR2 ZPR1

2.57e-04681334EFO_0022265
Diseasetriglycerides to total lipids in very small VLDL percentage

LDLR CELSR2 ZPR1 SMARCA4

2.72e-04691334EFO_0022341
Diseasesphingomyelin measurement

NVL LDLR BRAP CELSR2 ZPR1 SMARCA4 FRMD3

2.77e-042781337EFO_0010118
Diseaselevel of Sphingomyelin (d42:2) in blood serum

LDLR ZPR1 SMARCA4

3.00e-04291333OBA_2045183
Diseasemetabolic syndrome

HECTD4 ARID1A LDLR CELSR2 ZPR1 SMARCA4

3.02e-042001336EFO_0000195
Diseasefree cholesterol to total lipids in small VLDL percentage

LDLR CELSR2 ZPR1 SMARCA4

3.74e-04751334EFO_0022287
DiseaseLDL cholesterol change measurement

LDLR CELSR2

4.17e-0471332EFO_0007804
Diseasecatalase measurement

CELSR2 ABTB2

4.17e-0471332EFO_0008071
Diseasefree cholesterol measurement, very low density lipoprotein cholesterol measurement

PBX4 ARID1A LDLR CELSR2 ZPR1 SMARCA4

4.44e-042151336EFO_0008317, EFO_0008591
Diseasecarbohydrate intake measurement

HECTD4 BRAP CCDC171

4.84e-04341333EFO_0010811
Diseasechylomicron measurement, very low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio

LDLR CELSR2 SMARCA4

4.84e-04341333EFO_0008317, EFO_0008596, EFO_0020944
Diseasevery low density lipoprotein cholesterol measurement, lipid measurement

PBX4 ARID1A LDLR CELSR2 ZPR1 SMARCA4

5.01e-042201336EFO_0004529, EFO_0008317
DiseaseKartagener Syndrome

DNAH1 DNAAF5 LRRC56

5.27e-04351333C0022521
Diseaselow density lipoprotein cholesterol measurement, C-reactive protein measurement

HECTD4 BRAP CELSR2

5.27e-04351333EFO_0004458, EFO_0004611
DiseaseCiliary Dyskinesia, Primary, 1, With Or Without Situs Inversus

DNAH1 DNAAF5 LRRC56

5.27e-04351333C4551906
DiseasePolynesian Bronchiectasis

DNAH1 DNAAF5 LRRC56

5.27e-04351333C4317124
Diseasetotal cholesterol measurement, very low density lipoprotein cholesterol measurement

ARID1A LDLR METAP1 CELSR2 ZPR1 SMARCA4

5.51e-042241336EFO_0004574, EFO_0008317
Diseaseesterified cholesterol measurement, intermediate density lipoprotein measurement

CELSR2 SMARCA4

5.55e-0481332EFO_0008589, EFO_0008595
Diseaseprogeria (implicated_via_orthology)

POLG LMNB2

5.55e-0481332DOID:3911 (implicated_via_orthology)
Diseasebody weight

NPR3 ZBTB38 RTTN HECTD4 PPFIA3 ZZEF1 TRIM24 BRAP DGKK POLN DNA2 CCDC171 NOS3 KDM4B ARAP1

5.77e-04126113315EFO_0004338
Diseasevery low density lipoprotein cholesterol measurement, phospholipid measurement

PBX4 ARID1A LDLR CELSR2 ZPR1 SMARCA4

6.18e-042291336EFO_0004639, EFO_0008317
Diseasefree cholesterol to total lipids in large VLDL percentage

LDLR CELSR2 SMARCA4

6.22e-04371333EFO_0022281
Diseasefree cholesterol:total lipids ratio, intermediate density lipoprotein measurement

LDLR CELSR2 ZPR1 SMARCA4

6.29e-04861334EFO_0008595, EFO_0020945
Diseaseliver fibrosis measurement

LDLR BRAP ITPR3 CELSR2

6.29e-04861334EFO_0010576
Diseaseopportunistic bacterial infectious disease (implicated_via_orthology)

SMARCA2 SMARCA4

7.11e-0491332DOID:0050340 (implicated_via_orthology)
Diseaseimmunoglobulin M measurement

ODF1 SIGLEC1

7.11e-0491332EFO_0020466
DiseaseParoxysmal atrial fibrillation

USP34 PPFIA4 LRIG1 HERC1 NOS3

7.23e-041561335C0235480
Diseasefamilial atrial fibrillation

USP34 PPFIA4 LRIG1 HERC1 NOS3

7.23e-041561335C3468561
DiseasePersistent atrial fibrillation

USP34 PPFIA4 LRIG1 HERC1 NOS3

7.23e-041561335C2585653
Diseasetriglycerides to total lipids in large VLDL percentage

LDLR CELSR2 SMARCA4

7.27e-04391333EFO_0022332
Diseaselipid measurement, lipoprotein measurement

LDLR CELSR2 ZPR1 SMARCA4

7.47e-04901334EFO_0004529, EFO_0004732

Protein segments in the cluster

PeptideGeneStartEntry
TSLKEDVRRSAMLCI

BRAP

151

Q7Z569
VARTASEELACLLMD

ASB9

206

Q96DX5
CDKESNMERRVITIS

BUB1

201

O43683
LVDTLCMETQERDVR

CASS4

716

Q9NQ75
ALVERRDTLRLMCSS

CEACAM16

141

Q2WEN9
MDCSDLLRRQTSELE

CCDC171

246

Q6TFL3
AVDCMSRELVSLTSR

FBXO34

431

Q9NWN3
LVERDRATLAALETM

ALDH1A3

106

P47895
GCSSSEILRMERIIL

CCNI

121

Q14094
MVSRSEIDLLDIRTE

ANXA3

276

P12429
EESRLVAEMLCTATA

CFAP46

976

Q8IYW2
MITDLEARCLSLRVR

CFAP46

1726

Q8IYW2
ICSSAVRALELIRSM

CMSS1

161

Q9BQ75
KTAEDRRMSDLTCVL

C16orf78

21

Q8WTQ4
SALHLVRECSTEMAR

ABCA13

2411

Q86UQ4
VRECSTEMARLLDTI

ABCA13

2416

Q86UQ4
IMREDCTTIEVLLRN

ANKRD61

36

A6NGH8
AQCALRVTIITDEML

CELSR2

1111

Q9HCU4
ELRDSIVQCELLMLR

CCNQ

116

Q8N1B3
SEIQRLITEMEACIS

CCDC14

451

Q49A88
SDDAVSCSVMLEVLR

ERMP1

216

Q7Z2K6
DNTVVMEEIRRLCRT

ATG4B

171

Q9Y4P1
RVVIMCASSDTIRSI

NPR3

256

P17342
ECAALVRRTMESLEQ

POLN

816

Q7Z5Q5
CMEVILEKASASERR

MKRN2

241

Q9H000
LEITISEARCLELHM

MSANTD2

376

Q6P1R3
TEMEVDSSQLRRQLC

RANBP9

596

Q96S59
VLEASLCSLRTEMER

RABEP2

476

Q9H5N1
DELEERLERCMSIVT

INTS3

46

Q68E01
ERRIVAQLLTCMDDL

NVL

381

O15381
RELDSTERACDTLLM

ITPR3

2446

Q14573
EARTMAAEVLSRRCV

NCLN

71

Q969V3
DLVERVMVTRSLCAE

CAPN15

566

O75808
DCLEMLRENTLVTLA

ARID1A

2051

O14497
CDILVDDNTVMRLIT

ARIH1

236

Q9Y4X5
MRLCTSVTESEVARA

PMPCB

386

O75439
MDLEECILITDSTLI

FBXL2

291

Q9UKC9
TEMIIATRFLCSAVE

DGKK

666

Q5KSL6
QVVDLLVSMCRSALE

PARP8

556

Q8N3A8
LSSEDIEGMRLVCRL

METAP1

131

P53582
VSREELMTVLSRLAD

LAMA3

1601

Q16787
HDITIRTTTMARLEC

LRIG1

606

Q96JA1
RFIMILTEHLVRCET

NCBP1

716

Q09161
RMRDSQECILTETEA

KRT39

331

Q6A163
TDSMLELLECGRARV

MYO19

746

Q96H55
EEVERALCSRTMETA

MYO1A

311

Q9UBC5
ETLMRVDLENRCQSL

LMNB2

201

Q03252
ECLVSRHERSLRMTV

PPFIA3

121

O75145
ATLTRELSMCREQLL

PPFIA4

81

O75335
ESLEREMELLCLTGV

ATP9B

726

O43861
TDIRTLVRLMCLAAA

HERC1

3216

Q15751
VMEVLQATCRRTLEV

IKBKE

446

Q14164
AVMSCEVLRVLQLSD

CORO7

321

P57737
RMELAIRNSALDTCI

PLVAP

376

Q9BX97
REVKTSELRTMCLQV

IPO7

771

O95373
DMASATDITLRRVLV

FBXW11

346

Q9UKB1
EMSRVIRVSELSLCD

KIF20B

366

Q96Q89
SAVDIDRCLRKEVTM

POLG

1181

P54098
IGSLRTILDMVEREC

KDM4B

151

O94953
SIASELIEKRCRRMV

MYD88

206

Q99836
RETLCTELVLSDCML

LRRC45

56

Q96CN5
MAVAEVSRTCLLTVR

PLA2G4B

1

P0C869
RTRACLVMAQLLEDS

HECTD4

1861

Q9Y4D8
MAALSCLLDSVRRDI

ODF1

1

Q14990
CKELTLMTEEETRLR

KDM5A

636

P29375
LEDVAVCMDLDTRTT

NOS3

376

P29474
RTERAVLIDEVCTMN

PUM1

1091

Q14671
RQMLEICESCIREET

THAP12

236

O43422
CMTSATIDVTTVERL

PCDHAC1

736

Q9H158
STSSLKIMEDIIREC

PARP14

1101

Q460N5
IIRECMEITESLSLK

PARP14

1111

Q460N5
TCEAVMTLRSRLLDA

PBX4

196

Q9BYU1
EMRCTIRLLDDSEIS

FRMD3

31

A2A2Y4
EVINVCSDLRMLDSL

DNAH1

1286

Q9P2D7
ARVEEAITRMLVCAL

HSPBAP1

281

Q96EW2
LSRRECDTMADTLQR

BLM

896

P54132
VVRLMDVCATSRTDR

CDK4

71

P11802
RDCRAALAEITEMVA

FARP1

711

Q9Y4F1
SRECLTEMERTLALL

GID8

136

Q9NWU2
TARLTTDAARQICEM

CEP350

1441

Q5VT06
TDAARQICEMAELTR

CEP350

1446

Q5VT06
ERRMTLTDSIERCLK

IFRD1

121

O00458
DMEALCSVLRTLATD

IFRD2

366

Q12894
MDRVRDVVRASTFSC

HAS3

171

O00219
VRDCITESSLRSDMC

CCDC158

941

Q5M9N0
EEDSKMTRLISCRII

DNAAF5

711

Q86Y56
VEETDSRLCVRTVEM

CEP295

2316

Q9C0D2
ASSIRCMRRAVLSET

DNA2

131

P51530
EIRLLMEQESSACSR

PEX11B

141

O96011
TDRRVLLMFLDICSE

SPACA9

61

Q96E40
CMDILELSERLDLQR

RYR1

1646

P21817
IELLSMSSDRRLECI

CFAP47

241

Q6ZTR5
AVLALTTSLEDMRER

MTHFD1

571

P11586
VVERTRTATMLCAAS

PTPRD

136

P23468
VEDSLMIECSARDIL

HSPA14

386

Q0VDF9
DVIMDRSTCVQRATV

OR14A16

131

Q8NHC5
RLMFRDTVTLEDAIT

MCM9

581

Q9NXL9
ILLDQSECSMVRREA

RTTN

1421

Q86VV8
EDRCTEQKLSTAMRI

TRIM38

151

O00635
VRCLRTRTRMDEEVS

UVSSA

441

Q2YD98
RTCEIVEDTESSRMV

STK40

116

Q8N2I9
VVACMRRDTTLETAL

SMARCA2

396

P51531
DDLRLVRTLEMCVDT

LRRC56

66

Q8IYG6
VRTLEMCVDTREGSL

LRRC56

71

Q8IYG6
SNSMVDVCSVDRRSV

GNL3L

511

Q9NVN8
MRRSEVLAEESIVCL

PRC1

1

O43663
VVCMRRDTALETALN

SMARCA4

421

P51532
LSCKSEELRVMSERV

SPDL1

141

Q96EA4
IVTRGCETVEMTLRR

SIPA1L2

941

Q9P2F8
TSDSVRLKCREMLAA

TCEA1

136

P23193
LTACMENLVEEIRAR

ABTB2

231

Q8N961
MCPADETRTIISLDT

AGPS

246

O00116
SMTAEELTLEILDRR

ARAP1

1196

Q96P48
DVLHASVRRSTIVCM

CNBD2

191

Q96M20
SVRRSTIVCMEETEF

CNBD2

196

Q96M20
DSTNRDSLDMIERCI

CHAT

371

P28329
VEESLIDMRDLCSLL

CHAT

711

P28329
TTALCNEVERMLERH

USP53

186

Q70EK8
REVERVAMTAEACSR

TRAF2

291

Q12933
SAEIVCRMIRLLSLV

RNF213

871

Q63HN8
VRIDRICSLMAVENE

UNC45B

221

Q8IWX7
VCDDSGVIRLHMSRI

ZNF451

506

Q9Y4E5
MTRDLLKSETCSVEI

ZPR1

321

O75312
DIDCSSTIMLDNIVR

TRIM24

626

O15164
VALRDCIELFTTMET

USP4

776

Q13107
CVRALQLRSSEDEEM

RLF

376

Q13129
RQESALIEIMLCTIR

STAG2

516

Q8N3U4
LMEVTDSLDRCIQRL

UROC1

286

Q96N76
ACSLESRDVVLELMS

WDR97

1281

A6NE52
DTLLVRCEVSTRFDM

TRAF6

491

Q9Y4K3
IEMLEREVSVLRDQC

TNR

141

Q92752
DISTVLRIERCMLTR

PIEZO2

1676

Q9H5I5
DSRARSMAVIQCTVD

SIGLEC1

1356

Q9BZZ2
EDMVSSERTCTLAII

NME9

151

Q86XW9
CERIMDTISDRLRIP

ZDHHC23

66

Q8IYP9
TEALIVCEQDVSRMR

TSGA10

316

Q9BZW7
EAERCLILTTDSIMC

ZNF397

261

Q8NF99
LVSVAARECELLMLS

ZZEF1

936

O43149
KVSDSMRTASLCLER

ZBTB38

191

Q8NAP3
DSCISDMKTETREVL

USP34

3366

Q70CQ2
QRTTMILLCEDGSLR

UBR4

2226

Q5T4S7
LRSSCMVVRVDDLDI

UHRF1BP1

461

Q6BDS2
SREDLLMRLLECDVI

AK7

101

Q96M32
RDMRSCLTEAEAAVA

LDLR

706

P01130