Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	G protein-coupled receptor activity	OR2C1 OR10D3 OR6V1 NPR1 GPR12 CELSR3 OR4N5 GPR182 OR2C3 OR1F12P FZD10 TAS2R60 OR7A17 GPR88 OR7A10	6.74e-06	884	88	15	GO:0004930
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	OR2C1 OR10D3 OR6V1 NPR1 GPR12 CELSR3 OR4N5 AXL GPR182 OR2C3 OR1F12P FZD10 HTR3B TAS2R60 OR7A17 GPR88 OR7A10 CD200R1	2.07e-05	1353	88	18	GO:0004888
GeneOntologyMolecularFunction	palmitoyl hydrolase activity	PPT2 PPT1 ABHD10	2.91e-05	14	88	3	GO:0098599
GeneOntologyMolecularFunction	fatty acid ligase activity	ACSS1 ACSM2A SLC27A5	2.00e-04	26	88	3	GO:0015645
GeneOntologyMolecularFunction	CoA-ligase activity	ACSS1 ACSM2A SLC27A5	2.24e-04	27	88	3	GO:0016405
GeneOntologyMolecularFunction	acid-thiol ligase activity	ACSS1 ACSM2A SLC27A5	3.40e-04	31	88	3	GO:0016878
GeneOntologyMolecularFunction	olfactory receptor activity	OR2C1 OR10D3 OR6V1 OR4N5 OR2C3 OR1F12P OR7A17 OR7A10	6.29e-04	431	88	8	GO:0004984
GeneOntologyMolecularFunction	ligase activity, forming carbon-sulfur bonds	ACSS1 ACSM2A SLC27A5	7.81e-04	41	88	3	GO:0016877
GeneOntologyBiologicalProcess	detection of stimulus	OR2C1 OR10D3 OR6V1 OR4N5 OR2C3 OR1F12P TAS2R60 OR7A17 GPR88 PPEF1 OR7A10 NLRC4 RYR2	1.29e-05	722	89	13	GO:0051606
GeneOntologyBiologicalProcess	macromolecule depalmitoylation	PPT2 PPT1 ABHD10	2.73e-05	14	89	3	GO:0098734
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway	OR2C1 OR10D3 OR6V1 NPR1 GPR12 CELSR3 OR4N5 GPR182 OR2C3 OR1F12P FZD10 TAS2R60 OR7A17 PDE10A GPR88 CCL25 OR7A10	8.47e-05	1395	89	17	GO:0007186
GeneOntologyBiologicalProcess	detection of chemical stimulus	OR2C1 OR10D3 OR6V1 OR4N5 OR2C3 OR1F12P TAS2R60 OR7A17 OR7A10 RYR2	8.66e-05	524	89	10	GO:0009593
Domain	Dystrophin	DMD UTRN	2.14e-05	2	87	2	IPR016344
Domain	Palm_thioest	PPT2 PPT1	2.14e-05	2	87	2	PF02089
Domain	Palm_thioest	PPT2 PPT1	2.14e-05	2	87	2	IPR002472
Domain	AMP-bd_C	ACSS1 ACSM2A SLC27A5	6.33e-05	17	87	3	IPR025110
Domain	AMP-binding_C	ACSS1 ACSM2A SLC27A5	6.33e-05	17	87	3	PF13193
Domain	ROC_dom	DAPK1 LRRK1	1.28e-04	4	87	2	IPR020859
Domain	ROC	DAPK1 LRRK1	1.28e-04	4	87	2	PS51424
Domain	AMP-binding_CS	ACSS1 ACSM2A SLC27A5	2.35e-04	26	87	3	IPR020845
Domain	AMP_BINDING	ACSS1 ACSM2A SLC27A5	2.94e-04	28	87	3	PS00455
Domain	EF-hand_dom_typ1	DMD UTRN	3.18e-04	6	87	2	IPR015153
Domain	EF-hand_dom_typ2	DMD UTRN	3.18e-04	6	87	2	IPR015154
Domain	EF-hand_2	DMD UTRN	3.18e-04	6	87	2	PF09068
Domain	EF-hand_3	DMD UTRN	3.18e-04	6	87	2	PF09069
Domain	AMP-binding	ACSS1 ACSM2A SLC27A5	3.62e-04	30	87	3	PF00501
Domain	AMP-dep_Synth/Lig	ACSS1 ACSM2A SLC27A5	3.62e-04	30	87	3	IPR000873
Domain	7tm_1	OR2C1 OR6V1 GPR12 OR4N5 GPR182 OR2C3 OR1F12P OR7A17 GPR88 OR7A10	1.19e-03	677	87	10	PF00001
Domain	G_PROTEIN_RECEP_F1_1	OR2C1 OR6V1 GPR12 OR4N5 GPR182 OR2C3 OR1F12P OR7A17 GPR88 OR7A10	1.30e-03	685	87	10	PS00237
Domain	G_PROTEIN_RECEP_F1_2	OR2C1 OR6V1 GPR12 OR4N5 GPR182 OR2C3 OR1F12P OR7A17 GPR88 OR7A10	1.38e-03	691	87	10	PS50262
Domain	GPCR_Rhodpsn	OR2C1 OR6V1 GPR12 OR4N5 GPR182 OR2C3 OR1F12P OR7A17 GPR88 OR7A10	1.40e-03	692	87	10	IPR000276
Domain	-	PPT2 PPT1 ABHD10 LCAT	2.32e-03	119	87	4	3.40.50.1820
Domain	AB_hydrolase	PPT2 PPT1 ABHD10 LCAT	2.32e-03	119	87	4	IPR029058
Domain	Olfact_rcpt	OR2C1 OR6V1 OR4N5 OR2C3 OR1F12P OR7A17 OR7A10	2.39e-03	393	87	7	IPR000725
Domain	ZZ	DMD UTRN	3.13e-03	18	87	2	PF00569
Domain	ZF_ZZ_2	DMD UTRN	3.13e-03	18	87	2	PS50135
Domain	ZF_ZZ_1	DMD UTRN	3.13e-03	18	87	2	PS01357
Domain	CH	MICALL1 DMD UTRN	3.46e-03	65	87	3	SM00033
Domain	Znf_ZZ	DMD UTRN	3.48e-03	19	87	2	IPR000433
Domain	ZnF_ZZ	DMD UTRN	3.48e-03	19	87	2	SM00291
Domain	GPCR_Rhodpsn_7TM	OR2C1 OR6V1 GPR12 OR4N5 GPR182 OR2C3 OR7A17 GPR88 OR7A10	3.96e-03	670	87	9	IPR017452
Domain	CH	MICALL1 DMD UTRN	4.27e-03	70	87	3	PF00307
Domain	-	MICALL1 DMD UTRN	4.44e-03	71	87	3	1.10.418.10
Domain	Quino_amine_DH_bsu	UTP4 LRRK1	4.66e-03	22	87	2	IPR011044
Domain	CH	MICALL1 DMD UTRN	4.80e-03	73	87	3	PS50021
Domain	Actinin_actin-bd_CS	DMD UTRN	5.09e-03	23	87	2	IPR001589
Domain	Spectrin	DMD UTRN	5.09e-03	23	87	2	PF00435
Domain	ACTININ_2	DMD UTRN	5.09e-03	23	87	2	PS00020
Domain	ACTININ_1	DMD UTRN	5.09e-03	23	87	2	PS00019
Domain	CH-domain	MICALL1 DMD UTRN	5.18e-03	75	87	3	IPR001715
Domain	-	AGAP5 ANKDD1A DAPK1 LRRK1 AGAP9	6.06e-03	248	87	5	1.25.40.20
Domain	Ankyrin_rpt-contain_dom	AGAP5 ANKDD1A DAPK1 LRRK1 AGAP9	6.69e-03	254	87	5	IPR020683
Domain	ANK_REP_REGION	AGAP5 ANKDD1A DAPK1 LRRK1 AGAP9	6.69e-03	254	87	5	PS50297
Domain	-	PLCG1 DMD PPEF1 UTRN RYR2	7.48e-03	261	87	5	1.10.238.10
Domain	ArfGap	AGAP5 AGAP9	8.03e-03	29	87	2	SM00105
Domain	ArfGap	AGAP5 AGAP9	8.03e-03	29	87	2	PF01412
Domain	ARFGAP	AGAP5 AGAP9	8.03e-03	29	87	2	PS50115
Domain	Spectrin_repeat	DMD UTRN	8.03e-03	29	87	2	IPR002017
Domain	ArfGAP	AGAP5 AGAP9	8.03e-03	29	87	2	IPR001164
Pathway	WP_GPCRS_ODORANT	OR2C1 OR10D3 GPR12 GPR182 TAS2R60 OR7A17 GPR88 OR7A10	7.40e-07	157	67	8	MM15872
Pubmed	Claudin-5 localizes to the lateral membranes of cardiomyocytes and is altered in utrophin/dystrophin-deficient cardiomyopathic mice.	CLDN5 DMD UTRN	1.62e-08	3	89	3	15698839
Pubmed	Information coding in the olfactory system: evidence for a stereotyped and highly organized epitope map in the olfactory bulb.	OR2C1 OR7A17 OR7A10	5.78e-06	14	89	3	7528109
Pubmed	Decreased myocardial nNOS, increased iNOS and abnormal ECGs in mouse models of Duchenne muscular dystrophy.	DMD UTRN	6.48e-06	2	89	2	10525423
Pubmed	Distribution of dystrophin- and utrophin-associated protein complexes during activation of human neutrophils.	DMD UTRN	6.48e-06	2	89	2	20434517
Pubmed	Plasma lipidomic analysis shows a disease progression signature in mdx mice.	DMD UTRN	6.48e-06	2	89	2	34155298
Pubmed	In Vivo Genome Editing Restores Dystrophin Expression and Cardiac Function in Dystrophic Mice.	DMD UTRN	6.48e-06	2	89	2	28790199
Pubmed	Dystrophic changes in extraocular muscles after gamma irradiation in mdx:utrophin(+/-) mice.	DMD UTRN	6.48e-06	2	89	2	24466085
Pubmed	Crosstalk between RyR2 oxidation and phosphorylation contributes to cardiac dysfunction in mice with Duchenne muscular dystrophy.	DMD RYR2	6.48e-06	2	89	2	26555638
Pubmed	The Angiotensin Converting Enzyme Inhibitor Lisinopril Improves Muscle Histopathology but not Contractile Function in a Mouse Model of Duchenne Muscular Dystrophy.	DMD UTRN	6.48e-06	2	89	2	27110493
Pubmed	Rapid depletion of muscle progenitor cells in dystrophic mdx/utrophin-/- mice.	DMD UTRN	6.48e-06	2	89	2	24781208
Pubmed	Isolation and characterization of a genomic clone from the murine utrophin locus.	DMD UTRN	6.48e-06	2	89	2	8268660
Pubmed	Metabolic dysfunction and altered mitochondrial dynamics in the utrophin-dystrophin deficient mouse model of duchenne muscular dystrophy.	DMD UTRN	6.48e-06	2	89	2	25859846
Pubmed	G-utrophin, the autosomal homologue of dystrophin Dp116, is expressed in sensory ganglia and brain.	DMD UTRN	6.48e-06	2	89	2	7731967
Pubmed	Characterization of neuromuscular synapse function abnormalities in multiple Duchenne muscular dystrophy mouse models.	DMD UTRN	6.48e-06	2	89	2	27037492
Pubmed	Role of dystrophin and utrophin for assembly and function of the dystrophin glycoprotein complex in non-muscle tissue.	DMD UTRN	6.48e-06	2	89	2	16710609
Pubmed	Improvement in survival and muscle function in an mdx/utrn(-/-) double mutant mouse using a human retinal dystrophin transgene.	DMD UTRN	6.48e-06	2	89	2	16487708
Pubmed	Nonclinical Exon Skipping Studies with 2'-O-Methyl Phosphorothioate Antisense Oligonucleotides in mdx and mdx-utrn-/- Mice Inspired by Clinical Trial Results.	DMD UTRN	6.48e-06	2	89	2	30672725
Pubmed	Voltage-gated ion channel dysfunction precedes cardiomyopathy development in the dystrophic heart.	DMD UTRN	6.48e-06	2	89	2	21677768
Pubmed	Talin, vinculin and DRP (utrophin) concentrations are increased at mdx myotendinous junctions following onset of necrosis.	DMD UTRN	6.48e-06	2	89	2	7962191
Pubmed	Consequences of the combined deficiency in dystrophin and utrophin on the mechanical properties and myosin composition of some limb and respiratory muscles of the mouse.	DMD UTRN	6.48e-06	2	89	2	9713852
Pubmed	Skeletal muscle fibrosis in the mdx/utrn+/- mouse validates its suitability as a murine model of Duchenne muscular dystrophy.	DMD UTRN	6.48e-06	2	89	2	25607927
Pubmed	Does utrophin expression in muscles of mdx mice during postnatal development functionally compensate for dystrophin deficiency?	DMD UTRN	6.48e-06	2	89	2	8021701
Pubmed	Correlation of Utrophin Levels with the Dystrophin Protein Complex and Muscle Fibre Regeneration in Duchenne and Becker Muscular Dystrophy Muscle Biopsies.	DMD UTRN	6.48e-06	2	89	2	26974331
Pubmed	Developmental studies of dystrophin-positive fibers in mdx, and DRP localization.	DMD UTRN	6.48e-06	2	89	2	8433092
Pubmed	Second-generation compound for the modulation of utrophin in the therapy of DMD.	DMD UTRN	6.48e-06	2	89	2	25935002
Pubmed	Utrophin deficiency worsens cardiac contractile dysfunction present in dystrophin-deficient mdx mice.	DMD UTRN	6.48e-06	2	89	2	16024571
Pubmed	Disruption of PPT1 or PPT2 causes neuronal ceroid lipofuscinosis in knockout mice.	PPT2 PPT1	6.48e-06	2	89	2	11717424
Pubmed	Androgen receptor agonists increase lean mass, improve cardiopulmonary functions and extend survival in preclinical models of Duchenne muscular dystrophy.	DMD UTRN	6.48e-06	2	89	2	28453658
Pubmed	A quantitative study of bioenergetics in skeletal muscle lacking utrophin and dystrophin.	DMD UTRN	6.48e-06	2	89	2	11801396
Pubmed	Apo-dystrophin-1 and apo-dystrophin-2, products of the Duchenne muscular dystrophy locus: expression during mouse embryogenesis and in cultured cell lines.	DMD UTRN	6.48e-06	2	89	2	7987307
Pubmed	Utility of dystrophin and utrophin staining in childhood muscular dystrophy.	DMD UTRN	6.48e-06	2	89	2	16295426
Pubmed	Comparative analysis of the human dystrophin and utrophin gene structures.	DMD UTRN	6.48e-06	2	89	2	11861579
Pubmed	Distinct mechanical properties in homologous spectrin-like repeats of utrophin.	DMD UTRN	6.48e-06	2	89	2	30914715
Pubmed	Dystrophin is a microtubule-associated protein.	DMD UTRN	6.48e-06	2	89	2	19651889
Pubmed	Skeletal muscle-specific expression of a utrophin transgene rescues utrophin-dystrophin deficient mice.	DMD UTRN	6.48e-06	2	89	2	9590295
Pubmed	Comparison of skeletal muscle pathology and motor function of dystrophin and utrophin deficient mouse strains.	DMD UTRN	6.48e-06	2	89	2	22284942
Pubmed	Utrophin haploinsufficiency does not worsen the functional performance, resistance to eccentric contractions and force production of dystrophic mice.	DMD UTRN	6.48e-06	2	89	2	29879154
Pubmed	Haploinsufficiency of utrophin gene worsens skeletal muscle inflammation and fibrosis in mdx mice.	DMD UTRN	6.48e-06	2	89	2	17889902
Pubmed	Identification of Dp71 isoforms in the platelet membrane cytoskeleton. Potential role in thrombin-mediated platelet adhesion.	DMD UTRN	6.48e-06	2	89	2	12370193
Pubmed	Longitudinal metabolomic analysis of plasma enables modeling disease progression in Duchenne muscular dystrophy mouse models.	DMD UTRN	6.48e-06	2	89	2	32025735
Pubmed	Lifelong quercetin enrichment and cardioprotection in Mdx/Utrn+/- mice.	DMD UTRN	6.48e-06	2	89	2	27836895
Pubmed	BGP-15 Improves Aspects of the Dystrophic Pathology in mdx and dko Mice with Differing Efficacies in Heart and Skeletal Muscle.	DMD UTRN	6.48e-06	2	89	2	27750047
Pubmed	Prevention of dystrophin-deficient cardiomyopathy in twenty-one-month-old carrier mice by mosaic dystrophin expression or complementary dystrophin/utrophin expression.	DMD UTRN	6.48e-06	2	89	2	17967782
Pubmed	Diaphragm rescue alone prevents heart dysfunction in dystrophic mice.	DMD UTRN	6.48e-06	2	89	2	21062902
Pubmed	Matricellular Protein CCN5 Gene Transfer Ameliorates Cardiac and Skeletal Dysfunction in mdx/utrn (±) Haploinsufficient Mice by Reducing Fibrosis and Upregulating Utrophin Expression.	DMD UTRN	6.48e-06	2	89	2	35557546
Pubmed	Characterization of the Ang/Tie2 Signaling Pathway in the Diaphragm Muscle of DMD Mice.	DMD UTRN	6.48e-06	2	89	2	37626761
Pubmed	Molecular heterogeneity of the dystrophin-associated protein complex in the mouse kidney nephron: differential alterations in the absence of utrophin and dystrophin.	DMD UTRN	6.48e-06	2	89	2	15565469
Pubmed	The N- and C-Terminal Domains Differentially Contribute to the Structure and Function of Dystrophin and Utrophin Tandem Calponin-Homology Domains.	DMD UTRN	6.48e-06	2	89	2	26516677
Pubmed	Assessment of cardiac function in three mouse dystrophinopathies by magnetic resonance imaging.	DMD UTRN	6.48e-06	2	89	2	22209498
Pubmed	A Protocol for Simultaneous In Vivo Imaging of Cardiac and Neuroinflammation in Dystrophin-Deficient MDX Mice Using [18F]FEPPA PET.	DMD UTRN	6.48e-06	2	89	2	37108685
Pubmed	Prevention of the dystrophic phenotype in dystrophin/utrophin-deficient muscle following adenovirus-mediated transfer of a utrophin minigene.	DMD UTRN	6.48e-06	2	89	2	10694796
Pubmed	Dystrophin and dystrophin-related protein in the central nervous system of normal controls and Duchenne muscular dystrophy.	DMD UTRN	6.48e-06	2	89	2	8171962
Pubmed	Similar efficacy from specific and non-specific mineralocorticoid receptor antagonist treatment of muscular dystrophy mice.	DMD UTRN	6.48e-06	2	89	2	27822449
Pubmed	Micro-dystrophin gene therapy prevents heart failure in an improved Duchenne muscular dystrophy cardiomyopathy mouse model.	DMD UTRN	6.48e-06	2	89	2	33651713
Pubmed	Thermodynamic stability, unfolding kinetics, and aggregation of the N-terminal actin-binding domains of utrophin and dystrophin.	DMD UTRN	6.48e-06	2	89	2	22275054
Pubmed	NAD+ repletion improves muscle function in muscular dystrophy and counters global PARylation.	DMD UTRN	6.48e-06	2	89	2	27798264
Pubmed	Glycine administration attenuates progression of dystrophic pathology in prednisolone-treated dystrophin/utrophin null mice.	DMD UTRN	6.48e-06	2	89	2	31506484
Pubmed	Skeletal and cardiac myopathies in mice lacking utrophin and dystrophin: a model for Duchenne muscular dystrophy.	DMD UTRN	6.48e-06	2	89	2	9288752
Pubmed	Utrophin-dystrophin-deficient mice as a model for Duchenne muscular dystrophy.	DMD UTRN	6.48e-06	2	89	2	9288751
Pubmed	Enhanced currents through L-type calcium channels in cardiomyocytes disturb the electrophysiology of the dystrophic heart.	DMD UTRN	6.48e-06	2	89	2	24337461
Pubmed	Combined gene therapy via VEGF and mini-dystrophin synergistically improves pathologies in temporalis muscle of dystrophin/utrophin double knockout mice.	DMD UTRN	6.48e-06	2	89	2	33987645
Pubmed	Activation of calcineurin and stress activated protein kinase/p38-mitogen activated protein kinase in hearts of utrophin-dystrophin knockout mice.	DMD UTRN	6.48e-06	2	89	2	11297940
Pubmed	Utrophin up-regulation by artificial transcription factors induces muscle rescue and impacts the neuromuscular junction in mdx mice.	DMD UTRN	6.48e-06	2	89	2	29408646
Pubmed	The crystal structure of palmitoyl protein thioesterase-2 (PPT2) reveals the basis for divergent substrate specificities of the two lysosomal thioesterases, PPT1 and PPT2.	PPT2 PPT1	6.48e-06	2	89	2	12855696
Pubmed	Rescue of severely affected dystrophin/utrophin-deficient mice through scAAV-U7snRNA-mediated exon skipping.	DMD UTRN	6.48e-06	2	89	2	22388933
Pubmed	Functional correction in mouse models of muscular dystrophy using exon-skipping tricyclo-DNA oligomers.	DMD UTRN	6.48e-06	2	89	2	25642938
Pubmed	Activation of non-myogenic mesenchymal stem cells during the disease progression in dystrophic dystrophin/utrophin knockout mice.	DMD UTRN	6.48e-06	2	89	2	25859011
Pubmed	Satellite cells and utrophin are not directly correlated with the degree of skeletal muscle damage in mdx mice.	DMD UTRN	6.48e-06	2	89	2	15703201
Pubmed	Microtubule binding distinguishes dystrophin from utrophin.	DMD UTRN	6.48e-06	2	89	2	24706788
Pubmed	Utrophin suppresses low frequency oscillations and coupled gating of mechanosensitive ion channels in dystrophic skeletal muscle.	DMD UTRN	6.48e-06	2	89	2	25941878
Pubmed	Duchenne muscular dystrophy and the neuromuscular junction: the utrophin link.	DMD UTRN	6.48e-06	2	89	2	9297964
Pubmed	Dystrophin and utrophin do not play crucial roles in nonmuscle tissues in mice.	DMD UTRN	6.48e-06	2	89	2	10204788
Pubmed	SERCA1 overexpression minimizes skeletal muscle damage in dystrophic mouse models.	DMD UTRN	6.48e-06	2	89	2	25652448
Pubmed	Utrophin Compensates dystrophin Loss during Mouse Spermatogenesis.	DMD UTRN	6.48e-06	2	89	2	28785010
Pubmed	The role of proteases in excitation-contraction coupling failure in muscular dystrophy.	DMD UTRN	6.48e-06	2	89	2	25298424
Pubmed	Restoration of all dystrophin protein interactions by functional domains in trans does not rescue dystrophy.	DMD UTRN	6.48e-06	2	89	2	16307000
Pubmed	Expression of the dystrophin isoform Dp116 preserves functional muscle mass and extends lifespan without preventing dystrophy in severely dystrophic mice.	DMD UTRN	6.48e-06	2	89	2	21949353
Pubmed	Dystrophin and utrophin "double knockout" dystrophic mice exhibit a spectrum of degenerative musculoskeletal abnormalities.	DMD UTRN	6.48e-06	2	89	2	23097179
Pubmed	rAAV6-microdystrophin preserves muscle function and extends lifespan in severely dystrophic mice.	DMD UTRN	6.48e-06	2	89	2	16819550
Pubmed	The role of utrophin and Dp71 for assembly of different dystrophin-associated protein complexes (DPCs) in the choroid plexus and microvasculature of the brain.	DMD UTRN	6.48e-06	2	89	2	15501597
Pubmed	Enhanced expression of the alpha 7 beta 1 integrin reduces muscular dystrophy and restores viability in dystrophic mice.	DMD UTRN	6.48e-06	2	89	2	11257121
Pubmed	Characterization of dystrophin and utrophin diversity in the mouse.	DMD UTRN	6.48e-06	2	89	2	10072426
Pubmed	The sparing of extraocular muscle in dystrophinopathy is lost in mice lacking utrophin and dystrophin.	DMD UTRN	6.48e-06	2	89	2	9625743
Pubmed	Systemic human minidystrophin gene transfer improves functions and life span of dystrophin and dystrophin/utrophin-deficient mice.	DMD UTRN	6.48e-06	2	89	2	18973234
Pubmed	Metabolic profiles of dystrophin and utrophin expression in mouse models of Duchenne muscular dystrophy.	DMD UTRN	6.48e-06	2	89	2	12387876
Pubmed	Renin-angiotensin-aldosterone system inhibitors improve membrane stability and change gene-expression profiles in dystrophic skeletal muscles.	DMD UTRN	6.48e-06	2	89	2	27881412
Pubmed	Nanoscale remodeling of ryanodine receptor cluster size underlies cerebral microvascular dysfunction in Duchenne muscular dystrophy.	DMD RYR2	6.48e-06	2	89	2	30181262
Pubmed	Dystrophins, utrophins, and associated scaffolding complexes: role in mammalian brain and implications for therapeutic strategies.	DMD UTRN	6.48e-06	2	89	2	20625423
Pubmed	Utrophin influences mitochondrial pathology and oxidative stress in dystrophic muscle.	DMD UTRN	6.48e-06	2	89	2	29065908
Pubmed	Stabilization of the cardiac sarcolemma by sarcospan rescues DMD-associated cardiomyopathy.	DMD UTRN	6.48e-06	2	89	2	31039133
Pubmed	Developmentally regulated expression and localization of dystrophin and utrophin in the human fetal brain.	DMD UTRN	6.48e-06	2	89	2	11796130
Pubmed	Dystrophin and dystrophin-related protein in the brains of normal and mdx mice.	DMD UTRN	6.48e-06	2	89	2	8159184
Pubmed	Dystrophin and utrophin: genetic analyses of their role in skeletal muscle.	DMD UTRN	6.48e-06	2	89	2	10679963
Pubmed	TAT-μUtrophin mitigates the pathophysiology of dystrophin and utrophin double-knockout mice.	DMD UTRN	6.48e-06	2	89	2	21565990
Pubmed	Generation and characterization of transgenic mice with the full-length human DMD gene.	DMD UTRN	6.48e-06	2	89	2	18083704
Pubmed	Expression of the dystrophin-related protein (utrophin) gene during mouse embryogenesis.	DMD UTRN	6.48e-06	2	89	2	8130373
Pubmed	Early Inflammation in Muscular Dystrophy Differs between Limb and Respiratory Muscles and Increases with Dystrophic Severity.	DMD UTRN	6.48e-06	2	89	2	33497702
Pubmed	Dystrophin and dystrophin-related protein (utrophin) distribution in normal and dystrophin-deficient skeletal muscles.	DMD UTRN	6.48e-06	2	89	2	8186702
Pubmed	ANG1 treatment reduces muscle pathology and prevents a decline in perfusion in DMD mice.	DMD UTRN	6.48e-06	2	89	2	28334037
Pubmed	Contemporary cardiac issues in Duchenne muscular dystrophy. Working Group of the National Heart, Lung, and Blood Institute in collaboration with Parent Project Muscular Dystrophy.	DMD UTRN	6.48e-06	2	89	2	25940966
Cytoband	3q13.2	ABHD10 SIDT1 CD200R1	3.04e-05	31	89	3	3q13.2
GeneFamily	Acyl-CoA synthetase family	ACSS1 ACSM2A SLC27A5	8.56e-05	26	60	3	40
GeneFamily	X-linked mental retardation\|Rho GTPase activating proteins\|BAR-PH domain containing	AGAP5 AGAP9	1.43e-03	17	60	2	1291
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	DMD UTRN	1.60e-03	18	60	2	91
GeneFamily	G protein-coupled receptors, Class A orphans	GPR12 GPR182 GPR88	2.21e-03	78	60	3	262
ToppCell	3'-GW_trimst-1-SmallIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NPR1 GPR182 CD40 CLDN5 ITGA2B ACSM2A	1.77e-06	182	89	6	fc020d784ab81af80d9331cc322b7c259284eaef
ToppCell	3'-GW_trimst-1-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	WFS1 SLC22A23 GPR182 CD40 CLDN5 ITGA2B	1.95e-06	185	89	6	fb84fcf7f51f53489bcb3962fa9cb483e48257ed
ToppCell	3'-Child09-12-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NPR1 WFS1 GPR182 CLDN5 ITGA2B ACSM2A	1.95e-06	185	89	6	9de1db2ce9e44956b1214daf6e1e161334679c88
ToppCell	3'-Child09-12-SmallIntestine-Endothelial-lymphatic_endothelial\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NPR1 WFS1 GPR182 CLDN5 ITGA2B ACSM2A	1.95e-06	185	89	6	18f5d9438c76e37988a7d17aa2a080af6bedbfc4
ToppCell	3'-GW_trimst-1-SmallIntestine-Endothelial-lymphatic_endothelial\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	WFS1 GPR182 CD40 CLDN5 ITGA2B ACSM2A	2.01e-06	186	89	6	9d250d5ae7cf9129be05b41d70cb6c3a046c5f1e
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Endothelial-lymphatic_endothelial\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	WFS1 SLC22A23 GPR182 CLDN5 ITGA2B UTRN	2.42e-06	192	89	6	fa0ef05a32c661bdd59b5a9b6f75fd647ee937f3
ToppCell	368C-Endothelial_cells-Endothelial-F_(Lymphatics)\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	GPR12 WFS1 SBSPON GPR182 ANKDD1A FZD10	2.42e-06	192	89	6	b016e229300c183e14c0e2bba494bf49c7899112
ToppCell	368C-Endothelial_cells-Endothelial-F_(Lymphatics)-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	GPR12 WFS1 SBSPON GPR182 ANKDD1A FZD10	2.42e-06	192	89	6	ac96831492c62ad9e1f7d0b764fbdf7d8a189ad9
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	WFS1 SLC22A23 GPR182 CLDN5 ITGA2B UTRN	2.42e-06	192	89	6	4e63d95f75fe6eb3f817e84528883e95093c5bbd
ToppCell	COVID-19-Myeloid-Migratory_DC\|COVID-19 / Condition, Lineage and Cell class	SLC12A3 CD40 GPC5 LRRK1 PRAME NUAK2	2.81e-06	197	89	6	b6d6cdae33753c1e38394f1f879e00b87f9c0496
ToppCell	PND07-28-samps-Myeloid-Macrophage-macrophage-B\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	PPT2 AXL AMZ1 CD200R1 GSR	1.74e-05	160	89	5	694bf1f1952bd8ab444819f533da24fa2b73f701
ToppCell	wk_15-18-Epithelial-Airway_epithelial_progenitor-epi-prox-progenitor_intermediate_\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	PCDHGC5 DAPK1 GPC5 DMD NUAK2	2.02e-05	165	89	5	f6887c64af0f26e33316bc5587487e24d76ece2a
ToppCell	368C-Endothelial_cells-Endothelial-F_(Lymphatics)\|368C / Donor, Lineage, Cell class and subclass (all cells)	GPR12 SBSPON GPR182 FZD10 CLDN5	2.20e-05	168	89	5	a74c8a9e3299183fba31ce3053ef325b5dbcd104
ToppCell	PND28-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_prolif\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FAM193B PPT2 AMZ1 TRPM2 GSR	2.20e-05	168	89	5	27cdf5cfa1d906868cfd60fdfab3cd51f3b3602f
ToppCell	368C-Endothelial_cells-Endothelial-F_(Lymphatics)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	GPR12 SBSPON GPR182 FZD10 CLDN5	2.20e-05	168	89	5	dae37b316ce80dfe4236c4ed7f0d4e7c340fa7b6
ToppCell	3'_v3-lymph-node_spleen-Myeloid_Dendritic-migDC\|lymph-node_spleen / Manually curated celltypes from each tissue	NPR1 SLC22A23 GPC5 VWCE PRAME	2.47e-05	172	89	5	1b24bed3cd8e3fa463c5e7cefdf9e99e639e2f84
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_10\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GPR12 SLC22A23 CD40 LRRK1 PRAME	2.54e-05	173	89	5	09a13407a41ff2cba82fc417b72bf9a24ce6c42e
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_10\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	GPR12 SLC22A23 CD40 LRRK1 PRAME	2.54e-05	173	89	5	bfec038a6783f166240da4861e100643c6ea80a5
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Endothelial-lymphatic_endothelial\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	WFS1 GPR182 CLDN5 ITGA2B UTRN	2.99e-05	179	89	5	abc6797bd3884aa75dca58fcb2523ee321243ab1
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	WFS1 GPR182 CLDN5 ITGA2B UTRN	2.99e-05	179	89	5	0b996d6e881f31e6b80d359f7caac70ecdeb9982
ToppCell	COVID-19-Heart-Lymph_EC\|Heart / Disease (COVID-19 only), tissue and cell type	WFS1 SLC22A23 GPR182 DAPK1 CLDN5	2.99e-05	179	89	5	411620201a860716a8773b92f50f7b94ef34a586
ToppCell	10x5'-Lung-Myeloid_Dendritic-migDC\|Lung / Manually curated celltypes from each tissue	NPR1 SLC12A3 SLC22A23 LRRK1 NUAK2	3.07e-05	180	89	5	e9e8992deb0beeee5548910e4616e7c990763d99
ToppCell	367C-Endothelial_cells-Endothelial-F_(Lymphatics)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	WFS1 SLC22A23 GPR182 FZD10 CLDN5	3.15e-05	181	89	5	b244ecaa442bbef51289d8ec574ef08fa9e96318
ToppCell	VE-matDC\|VE / Condition, Cell_class and T cell subcluster	SLC22A23 CD40 LRRK1 DMD PRAME	3.15e-05	181	89	5	982fd96ef75bc9ab2c2f4970c01b76ba7a164871
ToppCell	367C-Endothelial_cells-Endothelial-F_(Lymphatics)\|367C / Donor, Lineage, Cell class and subclass (all cells)	WFS1 SLC22A23 GPR182 FZD10 CLDN5	3.15e-05	181	89	5	dd79de8098edb385a0f85d0e9621503cdf76ec43
ToppCell	VE-matDC-\|VE / Condition, Cell_class and T cell subcluster	SLC22A23 CD40 LRRK1 DMD PRAME	3.15e-05	181	89	5	6252184ef098b911df50be4fe1b5565849a5b6b8
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR12 SLC12A3 GPR182 CLDN5 COQ7	3.32e-05	183	89	5	bc24145855bf4d027a8058bf92bc796c10f241bb
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR12 SLC12A3 GPR182 CLDN5 COQ7	3.32e-05	183	89	5	4c325ee6da070513097a11445ec95b0415ffd8a2
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NPR1 SBSPON GAS1 PCOLCE2 CLDN5	3.59e-05	186	89	5	1094c7140131454b2583200e1c01e81ccab3db23
ToppCell	PCW_05-06-Endothelial-Endothelial_mature-lymphatic\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	NPR1 GPR182 CD40 CLDN5 ACSM2A	3.59e-05	186	89	5	86b218a400f9c64f92b050f00b49f09647b17437
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SFTPB SBSPON SLC22A23 DAPK1 UTRN	3.59e-05	186	89	5	3aebe163799109ffc67e4e10ee47c2dd0886a92c
ToppCell	PCW_05-06-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	NPR1 GPR182 CD40 CLDN5 ACSM2A	3.59e-05	186	89	5	f51c76b1c3c6c49e0ebc9a913d8413e0b6a04d80
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SFTPB SBSPON SLC22A23 DAPK1 UTRN	3.68e-05	187	89	5	58d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	WFS1 GPR182 ANKDD1A CLDN5 UTRN	3.68e-05	187	89	5	65d406122dffe18279f14a1ed35ba091730b97be
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	WFS1 GPR182 ANKDD1A CLDN5 UTRN	3.68e-05	187	89	5	4c15c0ed41a55271fc793cb76fee97fa64190369
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	WFS1 GPR182 ANKDD1A CLDN5 UTRN	3.68e-05	187	89	5	5274f2b302bbf7fed30c480af4f35058d2cf61e0
ToppCell	(3)_DC_activated\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	SLC12A3 CD40 LRRK1 PRAME NUAK2	3.87e-05	189	89	5	e977838793fc0eb1499e81018e33e4ccb4a5f0c5
ToppCell	3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	WFS1 GPR182 CLDN5 ITGA2B UTRN	3.97e-05	190	89	5	32400c62cb9de4c2b24af4206c21a0215ab12212
ToppCell	normal_Lung-Endothelial_cells-Lymphatic_ECs\|normal_Lung / Location, Cell class and cell subclass	WFS1 GPR182 FZD10 CLDN5 ACSM2A	3.97e-05	190	89	5	2185db6007404a2b22325f91460dd17635be9bba
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NPR1 SBSPON GAS1 PCOLCE2 CLDN5	3.97e-05	190	89	5	92710caaff05123cf8e909319d7ac441d9b31a66
ToppCell	3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	WFS1 GPR182 CLDN5 ITGA2B UTRN	3.97e-05	190	89	5	b2bd2cb384bb8a5662064ed1aee68e905e1f780d
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-cycling_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NPR1 CD40 CLDN5 ACSM2A UTRN	3.97e-05	190	89	5	d4aefae2d3164db6a9e953c54af0151501e9d1da
ToppCell	droplet-Heart-nan-3m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS10 AXL GAS1 PCOLCE2 RYR2	3.97e-05	190	89	5	96a92212ea3fb35fa3d0da495e504edc61c71c23
ToppCell	(3)_MNP-(3)_DC_activated\|(3)_MNP / Lung cell shreds - cell class (v4) and cell subclass (v4)	SLC12A3 SLC22A23 LRRK1 PRAME NUAK2	4.07e-05	191	89	5	0353bf797c4ef237b9bb82460c173c7d03cb8883
ToppCell	3'-Pediatric_IBD-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	WFS1 GPR182 CLDN5 ITGA2B ACSM2A	4.07e-05	191	89	5	361b123c8289015206d5e706ab2c615d9a724179
ToppCell	3'-Pediatric_IBD-SmallIntestine-Endothelial-lymphatic_endothelial\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	WFS1 GPR182 CLDN5 ITGA2B ACSM2A	4.07e-05	191	89	5	011dc22c488369734749e839d65d52fe46b6a1a4
ToppCell	10x3'2.3-week_14-16-Endothelial-stroma-immature_EC\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	NPR1 WFS1 GPR182 CLDN5 ACSM2A	4.17e-05	192	89	5	5af3b2b38495e925497c48f605d618bbf970965d
ToppCell	BAL-Severe-Myeloid-cDC-cDC-cDC_10\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SLC12A3 GPC5 LRRK1 PRAME NUAK2	4.27e-05	193	89	5	7426a30ed01e5c8376b3e0ebe0f1057cfee88340
ToppCell	BAL-Severe-Myeloid-cDC-cDC-cDC_10\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SLC12A3 GPC5 LRRK1 PRAME NUAK2	4.27e-05	193	89	5	a2194012dfa0174c6160900625c44e0fd04c50e7
ToppCell	5'-Adult-SmallIntestine-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	WFS1 GPR182 FZD10 CLDN5 ACSM2A	4.38e-05	194	89	5	937ee85ffd50869b60f0f6e91017ab77e8b24c0b
ToppCell	3'-Adult-LymphNode-Endothelial-lymphatic_endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	WFS1 SBSPON GPR182 FZD10 CLDN5	4.60e-05	196	89	5	a2845436003e9adf34677eb81e78f8334ff01faa
ToppCell	Endothelial_cells-Endothelial-B\|Endothelial_cells / lung cells shred on cell class, cell subclass, sample id	WFS1 SBSPON SLC22A23 GPR182 FZD10	4.60e-05	196	89	5	36f95f9ef74eb951e41ef46fd136ceaef45208fc
ToppCell	10x3'2.3-week_17-19-Endothelial-stroma-sinusoidal_EC\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	NPR1 WFS1 GPR182 CLDN5 PDE10A	4.71e-05	197	89	5	4e58bbf3ecb30b4c8199adcc04d2eb134d90de56
ToppCell	Tracheal-10x5prime-Endothelial-Endothelia_lymphatic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	WFS1 SBSPON GPR182 CLDN5 ACSM2A	4.83e-05	198	89	5	05429f18e1d74880c1835568c86177f661b3477a
ToppCell	Tracheal-10x5prime-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	WFS1 SBSPON GPR182 CLDN5 ACSM2A	4.83e-05	198	89	5	306e28d31fd587409a12dcccc6b2abd7dc9c2e0a
ToppCell	COVID-19-Myeloid-Migratory_DC\|Myeloid / Condition, Lineage and Cell class	SLC12A3 SLC22A23 GPC5 DMD PRAME	4.83e-05	198	89	5	90f3b227cbc61c268d6d94bc9945a08d83d2d3d5
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating-Cycling_Progenitors\|1_mon / Sample Type, Dataset, Time_group, and Cell type.	GAS1 DAPK1 DMD UTRN NUAK2	4.94e-05	199	89	5	358c4b3037f59378db8916a2fbe9ed4830cf1449
ToppCell	Bronchial-NucSeq-Stromal-Myofibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	AXL SBSPON B3GALNT2 DMD RYR2	5.06e-05	200	89	5	a66449b22b39dd6987fc2c3ed160d24564234ced
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	SFTPB SBSPON SLC22A23 DAPK1 UTRN	5.06e-05	200	89	5	ddfb1f006365bf16203ee49f20200f68220cc288
ToppCell	Tracheal-10x3prime_v2-Endothelial-Endothelia_lymphatic\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	WFS1 SBSPON GPR182 CLDN5 ACSM2A	5.06e-05	200	89	5	b515b2ab0c3f5928dd67f2f227fc932451c272bb
ToppCell	Bronchial-10x5prime-Immune_Myeloid-Dendritic_cell-DC_activated\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SLC12A3 CD40 GPC5 LRRK1 PRAME	5.06e-05	200	89	5	a4c41509ca936e137230a6ae548c90f18a566d12
ToppCell	Tracheal-10x3prime_v2-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	WFS1 SBSPON GPR182 CLDN5 ACSM2A	5.06e-05	200	89	5	35f6c7f2469d12748c27f2a5d4a161ef839b4a07
ToppCell	(53)_Lymphoid_DC\|World / shred on Cell_type and subtype	SLC22A23 DAPK1 GPC5 DMD PRAME	6.09e-05	208	89	5	30212cfacad94a7cc562a69efa73a31259851515
ToppCell	LV-03._Atrial_Cardiomyocyte\|LV / Chamber and Cluster_Paper	OTOP2 HAPLN4 DMD RYR2	9.86e-05	120	89	4	3b77bd0e3630cdd45001cecf5e47660a90ebc92e
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SFTPB SLC22A23 DAPK1 UTRN	1.34e-04	130	89	4	6434d9106ccb38786dad36fab80163dfc07b6eb7
ToppCell	LV-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	OTOP2 HAPLN4 DMD RYR2	1.34e-04	130	89	4	a3e12984fb61311e49cc76c59f74f4dffc48faa1
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Macroglial-oligodendrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCOLCE2 CPOX CCL25 NLRC4	1.42e-04	132	89	4	3661665ed5b257f51530122cb9a9c849b5baa1fb
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D231\|Adult / Lineage, Cell type, age group and donor	CELSR3 SFTPB DISP3 GPC5	1.42e-04	132	89	4	8d30b71776f5f6da55dc78e0c5cb27be460004e3
ToppCell	Substantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Alcam_(Alcam)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	GPR182 GAS1 FZD10 NUAK2	1.89e-04	142	89	4	6a656d28c9f5dfb03a3a2d908cf2edbe0a5b1206
ToppCell	Substantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	GPR182 GAS1 FZD10 NUAK2	1.89e-04	142	89	4	671ba8869db7a6dc69fd1caf0e561f15a312b170
ToppCell	Substantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_2\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	GPR182 GAS1 FZD10 NUAK2	1.89e-04	142	89	4	3557084150670fd2e2634fc674f228ab85181b59
ToppCell	Substantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Alcam_(Alcam)-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	GPR182 GAS1 FZD10 NUAK2	1.89e-04	142	89	4	a3d1f4b570b75402171e38c5a7c88e2896520c8f
ToppCell	Hippocampus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Cbln1-Excitatory_Neuron.Slc17a7.Cbln1-Gpr88_(Medial_entorrhinal_cortex)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	WFS1 OTOP2 GPR88	1.92e-04	56	89	3	a310f50724ada8da92257c54b18d9214d7415010
ToppCell	Hippocampus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Cbln1-Excitatory_Neuron.Slc17a7.Cbln1-Gpr88_(Medial_entorrhinal_cortex)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	WFS1 OTOP2 GPR88	1.92e-04	56	89	3	4740900fffc892200f3e2480328eb43cb6d19f20
ToppCell	BAL-Control-Myeloid-cDC-cDC-cDC_4\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ADAMTS10 SLC12A3 MROH7 CD200R1	1.94e-04	143	89	4	5a279da1cd8e63db32f7c85a73b493c2121d0a96
ToppCell	BAL-Control-Myeloid-cDC-cDC-cDC_4\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ADAMTS10 SLC12A3 MROH7 CD200R1	2.04e-04	145	89	4	997bd540c43725a85ca97e4b79ebe0d336860287
ToppCell	facs-Liver-Non-hepatocytes-3m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CELSR3 TRPM2 PCOLCE2 NLRC4	2.45e-04	152	89	4	b61d2f6ee819c8dd4b4b601a8bc8388b1983de58
ToppCell	PND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ADAMTS10 INTS5 PFAS CCL25	2.70e-04	156	89	4	895927228c93cd090303984c5be6ebfb59ed6f3a
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L6_IT\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	NPR1 AMZ1 TBR1 CD200R1	2.83e-04	158	89	4	9e0589f770920f8ac41cfe5cd0a29e9e7a04a308
ToppCell	droplet-Lung-nan-3m-Myeloid-Myeloid_Dendritic_Type_1\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DAPK1 HPS5 CD200R1 NUAK2	3.12e-04	162	89	4	8a488ecd25ef41468c3c7766eb936dbc2f7665a9
ToppCell	PND07-28-samps-Myeloid-Macrophage\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	AXL AMZ1 CD200R1 GSR	3.12e-04	162	89	4	7c73fe8388af370461e04097cf145cbc9847285b
ToppCell	Bronchial_Biopsy-Endothelial-Lymphatic\|Endothelial / Tissue, Lineage and Cell class of Lung Cells from 10X	SBSPON MROH7 ITGA2B ACSM2A	3.19e-04	163	89	4	961c3a1303108afd680365466045f3460a30a7b0
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c02-NCAM1\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ADAMTS10 SFTPB HTR3B TBR1	3.19e-04	163	89	4	1c014e373667be290d7fb5d24c06c6f313ac8fa3
ToppCell	Int-URO-Myeloid-tDC\|Int-URO / Disease, Lineage and Cell Type	SLC12A3 AXL GAS1 OR2C3	3.34e-04	165	89	4	9803c3db6cdcf925bea7d9c382bf4fd05acf3509
ToppCell	Endothelial-B-Donor_01\|World / lung cells shred on cell class, cell subclass, sample id	SBSPON GPR182 FZD10 CLDN5	3.34e-04	165	89	4	b6893882472aeb0d18e26f47eaec9d53688afcde
ToppCell	Endothelial-B-Donor_04\|World / lung cells shred on cell class, cell subclass, sample id	SBSPON GPR182 CLDN5 RYR2	3.50e-04	167	89	4	6a03d16165e0b003092c39972928981abd4a75aa
ToppCell	367C-Myeloid-Dendritic-pDC\|367C / Donor, Lineage, Cell class and subclass (all cells)	SLC12A3 AMZ1 SIDT1 GPC5	3.50e-04	167	89	4	650de8cd5df070639b8aa292aacead739cfdb02c
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS10 AXL HAPLN4 RYR2	3.50e-04	167	89	4	e228b8373ffd4436e6b944e26d0fadf3ac289b21
ToppCell	Cerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	GPR12 TRPM2 HAPLN4 DISP3	3.50e-04	167	89	4	9efb9511a211d0824bb97f82c1a5860c43d2138f
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS10 AXL HAPLN4 RYR2	3.50e-04	167	89	4	7cb1b11e8e24a10115e46ffbb74889e672a7a026
ToppCell	Cerebellum-Neuronal-Inhibitory\|Cerebellum / BrainAtlas - Mouse McCarroll V32	GPR12 TRPM2 HAPLN4 DISP3	3.50e-04	167	89	4	904c613aac3f9919a432b110bb1dcc832b5aec0a
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS10 AXL HAPLN4 RYR2	3.50e-04	167	89	4	bb53a478b5d821d6d82c15bc4ed075b67682457c
ToppCell	droplet-Fat-Bat-18m-Myeloid-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CELSR3 TRPM2 CD40 OCRL	3.58e-04	168	89	4	6fddc957a0503455d8c165862b5eb8e5fdb8a510
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Neuronal-SPN_Neuron_STR\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR12 TRPM2 PDE10A GPR88	3.58e-04	168	89	4	b87fc63f9e35dfcfc46cb129ea569e73c5e018bb
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Neuronal-medium_spiny_neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR12 TRPM2 PDE10A GPR88	3.58e-04	168	89	4	b96a48552f4236a95bbcdce2f1b05041086d7101
ToppCell	droplet-Fat-Bat-18m-Myeloid-myeloid_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CELSR3 TRPM2 CD40 OCRL	3.58e-04	168	89	4	794035cb63353a7d02fd9939deb5b4d075c9d95a
ToppCell	PND07-28-samps-Myeloid\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	PPT1 AXL CD200R1 GSR	3.58e-04	168	89	4	87512f9e5e95333e7ffc6efa1e93bab2ba9154c6
ToppCell	droplet-Fat-Bat-18m-Myeloid\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CELSR3 TRPM2 CD40 OCRL	3.58e-04	168	89	4	1e23b634f96e88b976a523ca1f3fc08f6fe9b239
ToppCell	droplet-Spleen-SPLEEN-1m-Myeloid-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AXL TRPM2 FZD10 PCOLCE2	3.66e-04	169	89	4	3f8aa6d2f9aa060ae1a0ea3eb47e794099fc2c2c
ToppCell	droplet-Spleen-SPLEEN-1m-Myeloid\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AXL TRPM2 FZD10 PCOLCE2	3.66e-04	169	89	4	26de495c7562e0740689d0f78e803698e3e793db
Disease	cerebral palsy (implicated_via_orthology)	AGAP5 AGAP9	3.72e-04	10	86	2	DOID:1969 (implicated_via_orthology)
Disease	neuronal ceroid lipofuscinosis (implicated_via_orthology)	PPT2 PPT1	7.47e-04	14	86	2	DOID:14503 (implicated_via_orthology)
Disease	myelodysplastic syndrome (is_marker_for)	CD40 PRAME	1.54e-03	20	86	2	DOID:0050908 (is_marker_for)
Disease	muscular dystrophy (implicated_via_orthology)	DMD UTRN	1.70e-03	21	86	2	DOID:9884 (implicated_via_orthology)
Disease	inflammatory bowel disease	GLMN CELSR3 SLC22A23 AMZ1 CD40 DHDDS	2.02e-03	449	86	6	EFO_0003767
Disease	ICAM-1 measurement	ZGLP1 SLC22A23	2.22e-03	24	86	2	EFO_0004520
Disease	chronic myeloid leukemia (is_marker_for)	CD40 PRAME	2.81e-03	27	86	2	DOID:8552 (is_marker_for)

Protein segments in the cluster

Peptide	Gene	Start	Entry
DWCLLAMNLGLPDLV	DAPK1	1326	P53355
ALCISQAWPGMARTI	ACSS1	496	Q9NUB1
MNLWLLACLVAGFLG	CCL25	1	O15444
CWLAVLVTMPAALGL	DISP3	601	Q9P2K9
NPKWASLNLGVLMCI	AGAP9	531	Q5VTM2
LLGLGNCRWLRCLMQ	AMZ1	266	Q400G9
MAPLWACILVAAGIL	HTR3B	6	O95264
ILNILCSLMEPWALG	ACSM2A	266	Q08AH3
TMIPDVDCLLWAIGR	GSR	321	P00390
LGLLPVMGWNCLRDE	GPR12	171	P47775
VPLCVDMCLNWLLNV	DMD	3171	P11532
LGLLMQRCWAEDPQE	NPR1	776	P16066
MAPACQILRWALALG	ADAMTS10	1	Q9H324
WNVLGCQGALLMHLL	ADAT1	306	Q9BUB4
GAEMWRQLILCKPSC	MROH7	796	Q68CQ1
MALRLCASLVAAPWV	OR1F12P	136	Q8NHA8
CALWMPQEAVLGLLP	GPR88	81	Q9GZN0
NVLEQLTALMLPWGC	NLRC4	876	Q9NPP4
PCSPQRLLNWMLALA	LRRK1	146	Q38SD2
MDAQTWPVGFRCLLL	GPC5	1	P78333
KAMGPDRAWSLLQEC	HPS5	1071	Q9UPZ3
MNPRACYALSLVLWL	OR4N5	136	Q8IXE1
LPQLAGKWQVLCMLS	PCDHGC5	6	Q9Y5F6
WQGLMQFTLPVRLCK	PDE10A	446	Q9Y233
MGIGCWRNPLLLLIA	CSTL1	1	Q9H114
MAGPRGALLAWCRRQ	MICALL1	1	Q8N3F8
MLCPWRTANLGLLLI	CD200R1	1	Q8TD46
TVPGAWLCLMALLQL	GAS1	16	P54826
WLCLMALLQLLGSAP	GAS1	21	P54826
MRGANAWAPLCLLLA	PCOLCE2	1	Q9UKZ9
MNPQLCWLLAVIACL	OR2C1	136	O95371
IMHPQLCLGLALASW	OR2C3	136	Q8N628
LLCNVILWIMPAFGA	OTOP2	501	Q7RTS6
RAMCVQLAGAAWAAP	OR6V1	136	Q8N148
MASPGCLWLLAVALL	PPT1	1	P50897
MLGLCGQRLPAAWVL	PPT2	1	Q9UMR5
PRLWLVLQVMGSCAA	FZD10	6	Q9ULW2
ALETMAWGRGPVCLL	GLYCTK	391	Q8IVS8
LLGEMPLWVCQSCRK	FAM193B	121	Q96PV7
MRNWLVLLCPCVLGA	B3GALNT2	1	Q8NCR0
MSCAGAAAAPRLWRL	COQ7	1	Q99807
NLELSLRIWMCGGQL	GALNTL5	336	Q7Z4T8
GRCWIFSCLNVMRLP	BLMH	71	Q13867
ILLNACCPGWVRTDM	CBR1	221	P16152
MVCARAALGPGALWA	HAPLN4	1	Q86UW8
LLLWLPGARCAIRMT	IGKV1-8	11	A0A0C4DH67
LDLNMFLPLGVDCWI	LCAT	86	P04180
ADARAAWMPACLGRK	CELSR3	2776	Q9NYQ7
LWERFCANIIKAGPM	DHDDS	11	Q86SQ9
GWLVQCLDPLQFMSL	RYR2	1616	Q92736
MALQLGRLSSGPCWL	CPOX	1	P36551
WLCAILIILAIAGMN	OTOL1	6	A6NHN0
MNPRICVALAVGTWL	OR10D3	136	Q8NH80
CMENILGLNLPWRSL	PPEF1	511	O14829
MGWNLVGPVVRCLLC	GLMN	61	Q92990
ALGVEWVLRRMLLPC	TAS2R60	41	P59551
AMCLLAVSPDGNWLA	UTP4	486	Q969X6
VNVPLCVDMCLNWLL	UTRN	2926	P46939
VLPCWPNSAAAAARM	TBR1	561	Q16650
LCELGRPSMVWLSAN	PRAME	471	P78395
AIPQAMLQACVGSWL	SFTPB	316	P07988
LMPGLAALCRDWQVL	SLC22A23	331	A1A5C7
MNPQLCGLLVLASWI	OR7A10	136	O76100
RAMCAGIWVLSAIIP	GPR182	171	O15218
MNPRLCGLLVLASWM	OR7A17	136	O14581
GALNELLQLWMGCRA	INTS5	171	Q6P9B9
MARALCPLQALWLLE	ITGA2B	1	P08514
ACGLIRWLLMVNPTR	NUAK2	276	Q9H093
VVIWLGDLNYRLCMP	OCRL	416	Q01968
MAVARLAAVAAWVPC	ABHD10	1	Q9NUJ1
ARLCFGMNALLLSAW	ANKDD1A	86	Q495B1
NPKWASLNLGVLMCI	AGAP5	486	A6NIR3
LILACGLPMWQVTAF	CLDN5	21	O00501
MLMAWCRGPVLLCLR	TRMT61B	1	Q9BVS5
CWLPRDQKLLLAGMH	MIOS	191	Q9NXC5
MAPALWRACNGLMAA	TMEM220	1	Q6QAJ8
MALCALSRLWPGAQA	SBSPON	6	Q8IVN8
ASQAVPALCMWLGLA	SLC27A5	181	Q9Y2P5
NGLWRVTLCMLAFPL	TRPM2	751	O94759
MRGCLRLALLCALPW	SIDT1	1	Q9NXL6
MWLFGCPLLLDDVAR	PFAS	61	O15067
RPAKCLTIMWALGQA	TMEM214	251	Q6NUQ4
MWAGLLLRAACVALL	VWCE	1	Q96DN2
PRMGRVPLAWCLALC	AXL	6	P30530
LPMWICGSQLVALNF	PLCG1	1026	P19174
CMLNIWGVILYLRLP	SLC12A3	146	P55017
MSGRLAWAQQLCLLP	RALGAPB	981	Q86X10
AWAQQLCLLPRGAKA	RALGAPB	986	Q86X10
CWDPMALGTQGRLLL	ZGLP1	81	P0C6A0
MVRLPLQCVLWGCLL	CD40	1	P25942
ALCGPRAWKETNMAR	WFS1	671	O76024