Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncatalytic activity, acting on DNA

ERVK-6 DDX12P ERCC4 CHD3 CHD4 ERVK-7 RFC2 ZRANB3 CRY1 DDX11 ERVK-8 EME2 CDK7

9.51e-1026210313GO:0140097
GeneOntologyMolecularFunctionaspartic-type endopeptidase activity

ERVK-6 ERVK-7 ERVK-21 ERVK-9 ERVK-8 ERVK-19

3.32e-08371036GO:0004190
GeneOntologyMolecularFunctionaspartic-type peptidase activity

ERVK-6 ERVK-7 ERVK-21 ERVK-9 ERVK-8 ERVK-19

3.93e-08381036GO:0070001
GeneOntologyMolecularFunctioncatalytic activity, acting on a nucleic acid

ERVK-6 DDX12P ERCC4 CHD3 CHD4 ERVK-7 RFC2 ZRANB3 CRY1 DDX11 SLFN13 DROSHA ERVK-8 METTL16 EME2 CDK7

1.93e-0764510316GO:0140640
GeneOntologyMolecularFunctionendonuclease activity

ERVK-6 ERCC4 ERVK-7 ZRANB3 SLFN13 DROSHA ERVK-8 EME2

5.20e-071361038GO:0004519
GeneOntologyMolecularFunctionhigh voltage-gated calcium channel activity

CACNA1C CACNA1D CACNA1F CACNA1S

6.42e-07141034GO:0008331
GeneOntologyMolecularFunctionalpha-tocopherol omega-hydroxylase activity

CYP4F2 CYP4F3 CYP4F11

1.32e-0651033GO:0052871
GeneOntologyMolecularFunctiontransition metal ion binding

TRHDE ERVK-6 HDAC6 MIOX CYP4F2 CHD3 CHD4 ERVK-7 ERVK-21 ERVK-9 PTCH1 ZRANB3 USP51 SLFN13 ERVK-8 ERVK-19 CYP4F3 CYP4F11 ALOX12 CA3

2.42e-06118910320GO:0046914
GeneOntologyMolecularFunctionnuclease activity

ERVK-6 ERCC4 ERVK-7 ZRANB3 SLFN13 DROSHA NME5 ERVK-8 EME2

3.10e-062311039GO:0004518
GeneOntologyMolecularFunctionRNA stem-loop binding

ERVK-6 ERVK-7 ERVK-8 METTL16

3.74e-06211034GO:0035613
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity

CACNA1C CACNA1D CACNA1F CACNA1S TMC1

3.84e-06461035GO:0005245
GeneOntologyMolecularFunctionATP-dependent activity, acting on DNA

DDX12P CHD3 CHD4 RFC2 ZRANB3 DDX11 CDK7

4.26e-061271037GO:0008094
GeneOntologyMolecularFunctionleukotriene-B4 20-monooxygenase activity

CYP4F2 CYP4F3 CYP4F11

4.60e-0671033GO:0050051
GeneOntologyMolecularFunctionalkane 1-monooxygenase activity

CYP4F2 CYP4F3 CYP4F11

4.60e-0671033GO:0018685
GeneOntologyMolecularFunctionvoltage-gated monoatomic cation channel activity

CACNA1C CACNA1D CACNA1F CACNA1S TMC1 KCNH6 KCNJ2

1.39e-051521037GO:0022843
GeneOntologyMolecularFunctionarachidonate omega-hydroxylase activity

CYP4F2 CYP4F3 CYP4F11

1.56e-05101033GO:0052869
GeneOntologyMolecularFunctionfatty acid omega-hydroxylase activity

CYP4F2 CYP4F3 CYP4F11

1.56e-05101033GO:0120250
GeneOntologyMolecularFunctionlong-chain fatty acid omega-hydroxylase activity

CYP4F2 CYP4F3 CYP4F11

1.56e-05101033GO:0102033
GeneOntologyMolecularFunctionRNA-DNA hybrid ribonuclease activity

ERVK-6 ERVK-7 ERVK-8

2.13e-05111033GO:0004523
GeneOntologyMolecularFunction20-hydroxy-leukotriene B4 omega oxidase activity

CYP4F2 CYP4F3

2.64e-0521032GO:0097258
GeneOntologyMolecularFunction20-aldehyde-leukotriene B4 20-monooxygenase activity

CYP4F2 CYP4F3

2.64e-0521032GO:0097259
GeneOntologyMolecularFunction[heparan sulfate]-glucosamine 3-sulfotransferase 3 activity

HS3ST3B1 HS3ST3A1

2.64e-0521032GO:0033872
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen

CYP4F2 CYP4F3 CYP4F11

3.67e-05131033GO:0016713
GeneOntologyMolecularFunctionRNA endonuclease activity, producing 5'-phosphomonoesters

ERVK-6 ERVK-7 DROSHA ERVK-8

3.87e-05371034GO:0016891
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity

CACNA1C CACNA1D CACNA1F CACNA1S TMC1 KCNH6 KCNJ2

4.42e-051821037GO:0005244
GeneOntologyMolecularFunctionRNA-directed DNA polymerase activity

ERVK-6 ERVK-7 ERVK-8

4.66e-05141033GO:0003964
GeneOntologyMolecularFunctionvoltage-gated channel activity

CACNA1C CACNA1D CACNA1F CACNA1S TMC1 KCNH6 KCNJ2

4.73e-051841037GO:0022832
GeneOntologyMolecularFunctionzinc ion binding

TRHDE ERVK-6 HDAC6 CHD3 CHD4 ERVK-7 ERVK-21 ERVK-9 PTCH1 ZRANB3 USP51 SLFN13 ERVK-8 ERVK-19 CA3

5.12e-0589110315GO:0008270
GeneOntologyMolecularFunctionRNA endonuclease activity

ERVK-6 ERVK-7 SLFN13 DROSHA ERVK-8

5.51e-05791035GO:0004521
GeneOntologyMolecularFunctionhydrolase activity, acting on ester bonds

ERVK-6 ERCC4 PTPMT1 ACHE ERVK-7 H6PD ZRANB3 ACOT12 SLFN13 DROSHA NME5 ERVK-8 EME2 CA3

6.77e-0580710314GO:0016788
GeneOntologyMolecularFunctionendopeptidase activity

ERVK-6 TRABD2B NRDC PIDD1 ERVK-7 ERVK-21 ERVK-9 ERVK-8 ERVK-19 PROC

7.65e-0543010310GO:0004175
GeneOntologyMolecularFunctionATP-dependent activity

DDX12P DYNC2H1 CHD3 CHD4 RFC2 ZRANB3 DDX11 SLFN13 ATP1A4 DYNC1H1 DNAH11 CDK7

7.66e-0561410312GO:0140657
GeneOntologyMolecularFunctionadiponectin binding

ADIPOR1 ADIPOR2

7.88e-0531032GO:0055100
GeneOntologyMolecularFunctionendonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters

ERVK-6 ERVK-7 DROSHA ERVK-8

9.22e-05461034GO:0016893
GeneOntologyMolecularFunctionATP hydrolysis activity

DDX12P DYNC2H1 CHD3 CHD4 RFC2 DDX11 SLFN13 ATP1A4 DYNC1H1 DNAH11

9.43e-0544110310GO:0016887
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DYNC2H1 DYNC1H1 DNAH11

1.03e-04181033GO:0008569
GeneOntologyMolecularFunctionpeptidase activity

TRHDE ERVK-6 TRABD2B NRDC PIDD1 ERVK-7 ERVK-21 ERVK-9 USP51 ERVK-8 ERVK-19 PROC

1.39e-0465410312GO:0008233
GeneOntologyMolecularFunctionadipokinetic hormone receptor activity

ADIPOR1 ADIPOR2

1.57e-0441032GO:0097003
GeneOntologyMolecularFunctiontriplex DNA binding

DDX12P DDX11

1.57e-0441032GO:0045142
GeneOntologyMolecularFunctionhelicase activity

DDX12P CHD3 CHD4 RFC2 ZRANB3 DDX11

1.70e-041581036GO:0004386
GeneOntologyMolecularFunctionarachidonate epoxygenase activity

CYP4F2 CYP4F3 CYP4F11

2.49e-04241033GO:0008392
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity involved in cardiac muscle cell action potential

CACNA1C CACNA1D

2.61e-0451032GO:0086007
GeneOntologyMolecularFunctionDNA helicase activity

DDX12P RFC2 ZRANB3 DDX11

2.96e-04621034GO:0003678
GeneOntologyMolecularFunctionarachidonate monooxygenase activity

CYP4F2 CYP4F3 CYP4F11

3.56e-04271033GO:0008391
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DYNC2H1 DYNC1H1 DNAH11

3.98e-04281033GO:0051959
GeneOntologyMolecularFunction[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity

HS3ST3B1 HS3ST3A1

5.44e-0471032GO:0008467
GeneOntologyMolecularFunctioncalcium channel activity

CACNA1C CACNA1D CACNA1F CACNA1S TMC1

5.49e-041291035GO:0005262
GeneOntologyMolecularFunctionRNA nuclease activity

ERVK-6 ERVK-7 SLFN13 DROSHA ERVK-8

6.98e-041361035GO:0004540
GeneOntologyMolecularFunctionaromatase activity

CYP4F2 CYP4F3 CYP4F11

7.74e-04351033GO:0070330
GeneOntologyMolecularFunctiondynein intermediate chain binding

DYNC2H1 DYNC1H1 DNAH11

9.12e-04371033GO:0045505
GeneOntologyMolecularFunctionATP-dependent chromatin remodeler activity

CHD3 CHD4 ZRANB3

9.12e-04371033GO:0140658
GeneOntologyMolecularFunctionDEAD/H-box RNA helicase binding

DROSHA SP7

9.26e-0491032GO:0017151
GeneOntologyMolecularFunctionDNA polymerase activity

ERVK-6 ERVK-7 ERVK-8

9.86e-04381033GO:0034061
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

CACNA1C CACNA1D CACNA1F CACNA1S TMC1

1.12e-031511035GO:0015085
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen

CYP4F2 CYP4F3 CYP4F11

1.15e-03401033GO:0016709
GeneOntologyMolecularFunction5'-3' DNA helicase activity

DDX12P DDX11

1.41e-03111032GO:0043139
GeneOntologyMolecularFunctionDNA endonuclease activity

ERCC4 ZRANB3 EME2

1.51e-03441033GO:0004520
GeneOntologyMolecularFunctioniron ion binding

MIOX CYP4F2 CYP4F3 CYP4F11 ALOX12

1.70e-031661035GO:0005506
GeneOntologyMolecularFunctiongated channel activity

CACNA1C CACNA1D CACNA1F CACNA1S TMC1 KCNH6 KCNJ2

1.73e-033341037GO:0022836
GeneOntologyMolecularFunctionmonoatomic cation channel activity

CACNA1C CACNA1D CACNA1F CACNA1S TMC1 KCNH6 KCNJ2

2.01e-033431037GO:0005261
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

CYP4F2 CYP4F3 CYP4F11

2.07e-03491033GO:0016712
GeneOntologyMolecularFunctionG-quadruplex DNA binding

DDX12P DDX11

2.30e-03141032GO:0051880
GeneOntologyMolecularFunctionarachidonate binding

CYP4F2 CYP4F11

2.65e-03151032GO:0050544
GeneOntologyMolecularFunctionheparan sulfate sulfotransferase activity

HS3ST3B1 HS3ST3A1

2.65e-03151032GO:0034483
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

CACNA1C CACNA1D CACNA1F CACNA1S TMC1 KCNH6 KCNJ2 ATP1A4

2.81e-034651038GO:0046873
GeneOntologyMolecularFunctionmonooxygenase activity

MIOX CYP4F2 CYP4F3 CYP4F11

2.98e-031151034GO:0004497
GeneOntologyMolecularFunctionicosanoid binding

CYP4F2 CYP4F11

3.02e-03161032GO:0050542
GeneOntologyMolecularFunctionicosatetraenoic acid binding

CYP4F2 CYP4F11

3.02e-03161032GO:0050543
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

CYP4F2 RIOX2 CYP4F3 CYP4F11 KDM6A

3.34e-031941035GO:0016705
GeneOntologyMolecularFunctionDNA replication origin binding

DDX12P DDX11

3.82e-03181032GO:0003688
GeneOntologyMolecularFunctionDNA nuclease activity

ERCC4 ZRANB3 EME2

5.03e-03671033GO:0004536
GeneOntologyMolecularFunctionsingle-stranded DNA binding

DDX12P ERCC4 ZRANB3 DDX11

5.14e-031341034GO:0003697
GeneOntologyMolecularFunctionmicrotubule motor activity

DYNC2H1 DYNC1H1 DNAH11

5.68e-03701033GO:0003777
GeneOntologyMolecularFunctionprotein-hormone receptor activity

ADIPOR1 ADIPOR2

5.69e-03221032GO:0016500
GeneOntologyMolecularFunctionphosphotransferase activity, for other substituted phosphate groups

PIGG FKTN

5.69e-03221032GO:0016780
GeneOntologyMolecularFunctionoxidoreductase activity, acting on CH-OH group of donors

MIOX CYP4F2 H6PD CYP4F3

5.70e-031381034GO:0016614
GeneOntologyMolecularFunctioncatalytic activity, acting on RNA

ERVK-6 DDX12P ERVK-7 SLFN13 DROSHA ERVK-8 METTL16

5.86e-034171037GO:0140098
GeneOntologyMolecularFunctionhistone modifying activity

HDAC6 RIOX2 TTLL12 USP51 KDM6A

6.70e-032291035GO:0140993
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

DDX12P DYNC2H1 CHD3 CHD4 RFC2 DDX11 SLFN13 ATP1A4 DYNC1H1 DNAH11

6.70e-0377510310GO:0017111
GeneOntologyMolecularFunctionhistone deacetylase binding

MAGEA10 HDAC6 CHD4 CRY1

7.10e-031471034GO:0042826
GeneOntologyMolecularFunctionoxidoreductase activity, acting on single donors with incorporation of molecular oxygen

MIOX ALOX12

7.90e-03261032GO:0016701
GeneOntologyMolecularFunctionlong-chain fatty acid binding

CYP4F2 CYP4F11

9.13e-03281032GO:0036041
GeneOntologyMolecularFunctioninward rectifier potassium channel activity

KCNH6 KCNJ2

9.13e-03281032GO:0005242
GeneOntologyMolecularFunctionhistone H3 demethylase activity

RIOX2 KDM6A

9.13e-03281032GO:0141052
GeneOntologyMolecularFunctionmonoatomic ion channel activity

CACNA1C CACNA1D CACNA1F CACNA1S TMC1 KCNH6 KCNJ2

9.69e-034591037GO:0005216
GeneOntologyBiologicalProcesscell-cell fusion

ERVK-6 CACNA1S ERVK-21 ERVK-9 ERVK-8 ERVK-19 ERVFRD-1

1.97e-07851017GO:0140253
GeneOntologyBiologicalProcesssyncytium formation by plasma membrane fusion

ERVK-6 CACNA1S ERVK-21 ERVK-9 ERVK-8 ERVK-19 ERVFRD-1

1.97e-07851017GO:0000768
GeneOntologyBiologicalProcesssyncytium formation

ERVK-6 CACNA1S ERVK-21 ERVK-9 ERVK-8 ERVK-19 ERVFRD-1

2.71e-07891017GO:0006949
GeneOntologyBiologicalProcessDNA repair

ERVK-6 DDX12P ERCC4 CHD4 ERVK-7 RFC2 ZRANB3 DDX11 TAF6L USP51 KHDC3L ERVK-8 SMARCD1 EME2 CDK7

5.96e-0764810115GO:0006281
GeneOntologyBiologicalProcessleukotriene B4 catabolic process

CYP4F2 CYP4F3 CYP4F11

2.26e-0661013GO:0036101
GeneOntologyBiologicalProcessDNA-templated DNA replication

ERVK-6 ERVK-7 RFC2 ZRANB3 DDX11 KHDC3L ERVK-8 EME2

2.68e-061781018GO:0006261
GeneOntologyBiologicalProcessDNA damage response

ERVK-6 DDX12P ERCC4 PIDD1 CHD4 ERVK-7 RFC2 ZRANB3 CRY1 DDX11 TAF6L USP51 KHDC3L ERVK-8 SMARCD1 EME2 CDK7

3.87e-0695910117GO:0006974
GeneOntologyBiologicalProcessleukotriene B4 metabolic process

CYP4F2 CYP4F3 CYP4F11

3.93e-0671013GO:0036102
GeneOntologyBiologicalProcessleukotriene catabolic process

CYP4F2 CYP4F3 CYP4F11

6.27e-0681013GO:0036100
GeneOntologyBiologicalProcessicosanoid catabolic process

CYP4F2 CYP4F3 CYP4F11

1.83e-05111013GO:1901523
GeneOntologyBiologicalProcessDNA replication

ERVK-6 DDX12P ERVK-7 RFC2 ZRANB3 DDX11 KHDC3L ERVK-8 EME2

2.28e-053121019GO:0006260
GeneOntologyBiologicalProcesslong-chain fatty acid catabolic process

CYP4F2 CYP4F3 CYP4F11

2.43e-05121013GO:0042758
GeneOntologyBiologicalProcessDNA integration

ERVK-6 ERVK-7 ERVK-8

3.15e-05131013GO:0015074
GeneOntologyBiologicalProcessglucose homeostasis

CACNA1C CACNA1D PTPMT1 PTCH1 CRY1 ADIPOR1 TBC1D1 LRP1 ADIPOR2

4.26e-053381019GO:0042593
GeneOntologyBiologicalProcesscarbohydrate homeostasis

CACNA1C CACNA1D PTPMT1 PTCH1 CRY1 ADIPOR1 TBC1D1 LRP1 ADIPOR2

4.36e-053391019GO:0033500
GeneOntologyBiologicalProcessleukotriene metabolic process

CYP4F2 CYP4F3 CYP4F11 ALOX12

4.77e-05411014GO:0006691
GeneOntologyBiologicalProcessregulation of heart rate by cardiac conduction

CACNA1C CACNA1D KCNH6 KCNJ2

4.77e-05411014GO:0086091
GeneOntologyBiologicalProcesspositive regulation of membrane depolarization

CACNA1C CACNA1D ALOX12

6.09e-05161013GO:1904181
GeneOntologyBiologicalProcessinorganic ion import across plasma membrane

CACNA1C CACNA1D CACNA1F CACNA1S KCNJ2 ATP1A4

7.10e-051421016GO:0099587
GeneOntologyBiologicalProcessinorganic cation import across plasma membrane

CACNA1C CACNA1D CACNA1F CACNA1S KCNJ2 ATP1A4

7.10e-051421016GO:0098659
GeneOntologyBiologicalProcessmenaquinone catabolic process

CYP4F2 CYP4F11

7.10e-0531012GO:0042361
GeneOntologyBiologicalProcessDNA recombination

ERVK-6 ERCC4 CHD4 ERVK-7 ZRANB3 USP51 KHDC3L ERVK-8 EME2

8.19e-053681019GO:0006310
GeneOntologyBiologicalProcesscalcium ion import across plasma membrane

CACNA1C CACNA1D CACNA1F CACNA1S

8.93e-05481014GO:0098703
GeneOntologyBiologicalProcesscalcium ion import into cytosol

CACNA1C CACNA1D CACNA1F CACNA1S

8.93e-05481014GO:1902656
GeneOntologyBiologicalProcessreplication fork processing

ZRANB3 DDX11 KHDC3L EME2

1.22e-04521014GO:0031297
GeneOntologyBiologicalProcessmenaquinone metabolic process

CYP4F2 CYP4F11

1.42e-0441012GO:0009233
GeneOntologyBiologicalProcessphylloquinone metabolic process

CYP4F2 CYP4F11

1.42e-0441012GO:0042374
GeneOntologyBiologicalProcessphylloquinone catabolic process

CYP4F2 CYP4F11

1.42e-0441012GO:0042376
GeneOntologyBiologicalProcessvitamin K catabolic process

CYP4F2 CYP4F11

1.42e-0441012GO:0042377
GeneOntologyBiologicalProcessfatty acid derivative catabolic process

CYP4F2 CYP4F3 CYP4F11

1.64e-04221013GO:1901569
GeneOntologyBiologicalProcessregulation of cellular response to stress

ERCC4 HDAC6 CRY1 DDX11 TAF6L USP51 KHDC3L LRP1 INSIG2 SMARCD1 KDM6A

1.66e-0459810111GO:0080135
GeneOntologyBiologicalProcessmembrane depolarization during cardiac muscle cell action potential

CACNA1C CACNA1D KCNJ2

1.88e-04231013GO:0086012
GeneOntologyBiologicalProcessDNA-templated DNA replication maintenance of fidelity

ZRANB3 DDX11 KHDC3L EME2

2.14e-04601014GO:0045005
GeneOntologyBiologicalProcesspositive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel

CACNA1C CACNA1D

2.35e-0451012GO:1904879
GeneOntologyBiologicalProcessDNA metabolic process

ERVK-6 DDX12P ERCC4 CHD4 ERVK-7 RFC2 ZRANB3 DDX11 TAF6L USP51 KHDC3L ERVK-8 SMARCD1 EME2 CDK7

2.42e-04108110115GO:0006259
GeneOntologyBiologicalProcessarachidonate metabolic process

CYP4F2 CYP4F3 CYP4F11 ALOX12

3.47e-04681014GO:0019369
GeneOntologyBiologicalProcessprostaglandin catabolic process

CYP4F2 CYP4F11

3.52e-0461012GO:1905344
GeneOntologyBiologicalProcessprostanoid catabolic process

CYP4F2 CYP4F11

3.52e-0461012GO:0062232
GeneOntologyBiologicalProcessorganic hydroxy compound catabolic process

MIOX CYP4F2 CYP4F3 CYP4F11

4.55e-04731014GO:1901616
GeneOntologyBiologicalProcessnegative regulation of growth

HDAC6 PTCH1 SESN1 BDKRB1 ADIPOR1 SEMA6D ADIPOR2

4.87e-042831017GO:0045926
GeneOntologyBiologicalProcessadiponectin-activated signaling pathway

ADIPOR1 ADIPOR2

4.91e-0471012GO:0033211
GeneOntologyBiologicalProcessnegative regulation of cell growth

HDAC6 SESN1 BDKRB1 ADIPOR1 SEMA6D ADIPOR2

6.19e-042121016GO:0030308
GeneOntologyBiologicalProcessacetate ester metabolic process

ACHE PEBP1

6.52e-0481012GO:1900619
GeneOntologyBiologicalProcessacetylcholine metabolic process

ACHE PEBP1

6.52e-0481012GO:0008291
GeneOntologyBiologicalProcessfatty acid derivative metabolic process

CYP4F2 CYP4F3 CYP4F11 ALOX12

7.07e-04821014GO:1901568
GeneOntologyBiologicalProcessmembrane depolarization during action potential

CACNA1C CACNA1D KCNJ2

7.24e-04361013GO:0086010
GeneOntologyBiologicalProcessDNA geometric change

DDX12P RFC2 ZRANB3 DDX11

8.45e-04861014GO:0032392
GeneOntologyBiologicalProcesscardiac muscle cell action potential

CACNA1C CACNA1D KCNH6 KCNJ2

8.83e-04871014GO:0086001
GeneOntologyBiologicalProcessregulation of cold-induced thermogenesis

NRDC ACHE ADIPOR1 DYNC1H1 ADIPOR2

9.13e-041521015GO:0120161
GeneOntologyBiologicalProcessimport across plasma membrane

CACNA1C CACNA1D CACNA1F CACNA1S KCNJ2 ATP1A4

9.45e-042301016GO:0098739
GeneOntologyBiologicalProcesscold-induced thermogenesis

NRDC ACHE ADIPOR1 DYNC1H1 ADIPOR2

1.03e-031561015GO:0106106
GeneOntologyBiologicalProcesscardiac muscle cell membrane repolarization

CACNA1D KCNH6 KCNJ2

1.06e-03411013GO:0099622
GeneOntologyBiologicalProcessregulation of membrane repolarization

CACNA1D KCNH6 KCNJ2

1.06e-03411013GO:0060306
GeneOntologyBiologicalProcessdouble-strand break repair

ERCC4 CHD4 DDX11 USP51 KHDC3L SMARCD1 EME2

1.08e-033241017GO:0006302
GeneOntologyBiologicalProcesschemical homeostasis

CACNA1C CACNA1D CACNA1F CACNA1S CCDC22 PTPMT1 PTCH1 BDKRB1 CRY1 ADIPOR1 KCNJ2 TBC1D1 LRP1 ATP1A4 ADIPOR2

1.09e-03124910115GO:0048878
GeneOntologyBiologicalProcessregulation of insulin secretion involved in cellular response to glucose stimulus

CACNA1D PTPMT1 TBC1D1 LRP1

1.09e-03921014GO:0061178
GeneOntologyCellularComponentCtf18 RFC-like complex

DDX12P RFC2 DDX11

1.32e-05101023GO:0031390
GeneOntologyCellularComponentL-type voltage-gated calcium channel complex

CACNA1C CACNA1D CACNA1S

2.40e-05121023GO:1990454
GeneOntologyCellularComponentvoltage-gated calcium channel complex

CACNA1C CACNA1D CACNA1F CACNA1S

7.45e-05461024GO:0005891
GeneOntologyCellularComponentstereocilium tip

TMC1 ESPNL PKHD1L1

1.62e-04221023GO:0032426
GeneOntologyCellularComponentcalcium channel complex

CACNA1C CACNA1D CACNA1F CACNA1S

4.49e-04731024GO:0034704
GeneOntologyCellularComponentT-tubule

CACNA1C CACNA1D CACNA1S KCNJ2

6.06e-04791024GO:0030315
GeneOntologyCellularComponenthistone deacetylase complex

HDAC6 CHD3 CHD4 TAF6L

7.99e-04851024GO:0000118
GeneOntologyCellularComponentendonuclease complex

PRKRA DROSHA EME2

1.21e-03431023GO:1905348
HumanPhenoComplex cardiac malformations

CACNA1C CCDC22 ERCC4 CHD4 RFC2 PTCH1 DDX11 FKTN NME5 SMARCD1 KDM6A DNAH11

6.23e-082573512HP:0002565
HumanPhenoAbnormal ventriculoarterial connection

CACNA1C CCDC22 ERCC4 CHD4 RFC2 PTCH1 DDX11 FKTN NME5 SMARCD1 KDM6A DNAH11

1.61e-072803512HP:0011563
HumanPhenoAbnormal connection of the cardiac segments

CACNA1C CCDC22 ERCC4 CHD4 RFC2 PTCH1 DDX11 FKTN NME5 SMARCD1 KDM6A DNAH11

1.88e-072843512HP:0011545
HumanPhenoConotruncal defect

CACNA1C CCDC22 ERCC4 CHD4 RFC2 PTCH1 DDX11 NME5 SMARCD1 KDM6A DNAH11

8.08e-072643511HP:0001710
HumanPhenoTetralogy of Fallot

CACNA1C CCDC22 ERCC4 CHD4 RFC2 PTCH1 DDX11 SMARCD1 KDM6A

2.82e-06185359HP:0001636
HumanPhenoEctopic anus

CCDC22 ERCC4 DYNC2H1 CHD4 PTCH1 KDM6A

3.34e-0593356HP:0004397
HumanPhenoAbnormal anus morphology

CACNA1C CCDC22 ERCC4 DYNC2H1 CHD4 PTCH1 FKTN KDM6A

1.04e-04224358HP:0034915
HumanPhenoCongenital malformation of the great arteries

CACNA1C CCDC22 ERCC4 CHD4 RFC2 PTCH1 DDX11 FKTN NME5 SMARCD1 KDM6A DNAH11

1.23e-045293512HP:0011603
HumanPhenoAbnormal cardiac atrium morphology

CACNA1C CACNA1D CCDC22 ERCC4 CHD3 CHD4 PIGG RFC2 FKTN NME5 SMARCD1 KDM6A DNAH11

1.23e-046173513HP:0005120
HumanPhenoAbnormality of the anus

CACNA1C CCDC22 ERCC4 DYNC2H1 CHD4 PTCH1 FKTN KDM6A

1.99e-04246358HP:0004378
MousePhenosmall mandibular coronoid process

CACNA1S PTCH1 PRKRA

1.27e-059763MP:0030283
DomainVDCC_L_a1su

CACNA1C CACNA1D CACNA1F CACNA1S

6.84e-104974IPR005446
DomainVDCC_a1su_IQ

CACNA1C CACNA1D CACNA1F CACNA1S

2.36e-087974IPR014873
DomainGPHH

CACNA1C CACNA1D CACNA1F CACNA1S

2.36e-087974PF16905
DomainGPHH_dom

CACNA1C CACNA1D CACNA1F CACNA1S

2.36e-087974IPR031649
DomainCa_chan_IQ

CACNA1C CACNA1D CACNA1F CACNA1S

2.36e-087974SM01062
DomainCa_chan_IQ

CACNA1C CACNA1D CACNA1F CACNA1S

2.36e-087974PF08763
DomainCAC1F_C

CACNA1C CACNA1D CACNA1F

1.36e-073973IPR031688
DomainCAC1F_C

CACNA1C CACNA1D CACNA1F

1.36e-073973PF16885
DomainVDCCAlpha1

CACNA1C CACNA1D CACNA1F CACNA1S

1.40e-0710974IPR002077
DomainDHC_N1

DYNC2H1 DYNC1H1 DNAH11

7.46e-068973PF08385
DomainDynein_heavy_dom-1

DYNC2H1 DYNC1H1 DNAH11

7.46e-068973IPR013594
DomainDynein_heavy_chain_D4_dom

DYNC2H1 DYNC1H1 DNAH11

4.74e-0514973IPR024317
DomainDynein_HC_stalk

DYNC2H1 DYNC1H1 DNAH11

4.74e-0514973IPR024743
DomainDynein_heavy_dom-2

DYNC2H1 DYNC1H1 DNAH11

4.74e-0514973IPR013602
DomainDHC_N2

DYNC2H1 DYNC1H1 DNAH11

4.74e-0514973PF08393
DomainMT

DYNC2H1 DYNC1H1 DNAH11

4.74e-0514973PF12777
DomainAAA_8

DYNC2H1 DYNC1H1 DNAH11

4.74e-0514973PF12780
DomainATPase_dyneun-rel_AAA

DYNC2H1 DYNC1H1 DNAH11

4.74e-0514973IPR011704
DomainAAA_5

DYNC2H1 DYNC1H1 DNAH11

4.74e-0514973PF07728
DomainDHC_fam

DYNC2H1 DYNC1H1 DNAH11

5.91e-0515973IPR026983
DomainDynein_heavy_dom

DYNC2H1 DYNC1H1 DNAH11

5.91e-0515973IPR004273
DomainDynein_heavy

DYNC2H1 DYNC1H1 DNAH11

5.91e-0515973PF03028
DomainCHDCT2

CHD3 CHD4

7.98e-053972PF08074
DomainCHDNT

CHD3 CHD4

7.98e-053972PF08073
DomainDUF1086

CHD3 CHD4

7.98e-053972IPR009462
DomainDUF1087

CHD3 CHD4

7.98e-053972IPR009463
DomainCHD_N

CHD3 CHD4

7.98e-053972IPR012958
DomainCHD_C2

CHD3 CHD4

7.98e-053972IPR012957
DomainDUF1087

CHD3 CHD4

7.98e-053972PF06465
DomainDUF1086

CHD3 CHD4

7.98e-053972PF06461
DomainDUF1087

CHD3 CHD4

7.98e-053972SM01147
DomainDUF1086

CHD3 CHD4

7.98e-053972SM01146
DomainChannel_four-helix_dom

CACNA1C CACNA1D CACNA1F CACNA1S

2.19e-0457974IPR027359
Domain-

CACNA1C CACNA1D CACNA1F CACNA1S

2.19e-04579741.20.120.350
DomainERCC4

ERCC4 EME2

2.64e-045972SM00891
DomainERCC4_domain

ERCC4 EME2

2.64e-045972IPR006166
DomainERCC4

ERCC4 EME2

2.64e-045972PF02732
DomainIon_trans_dom

CACNA1C CACNA1D CACNA1F CACNA1S KCNH6

3.20e-04114975IPR005821
DomainIon_trans

CACNA1C CACNA1D CACNA1F CACNA1S KCNH6

3.20e-04114975PF00520
DomainP-loop_NTPase

DYNC2H1 CHD3 CHD4 RFC2 ZRANB3 DDX11 SLFN13 ASPM HS3ST3B1 HS3ST3A1 DYNC1H1 NLRP8 DNAH11

4.35e-048489713IPR027417
Domain-

DYNC2H1 CHD3 CHD4 RFC2 ZRANB3 DDX11 SLFN13 HS3ST3B1 HS3ST3A1 DYNC1H1 NLRP8 DNAH11

4.79e-0474697123.40.50.300
DomainSNF2_N

CHD3 CHD4 ZRANB3

6.04e-0432973IPR000330
DomainSNF2_N

CHD3 CHD4 ZRANB3

6.04e-0432973PF00176
DomainDNA/RNA_helicase_DEAH_CS

CHD3 CHD4 DDX11

7.88e-0435973IPR002464
DomainDEAH_ATP_HELICASE

CHD3 CHD4 DDX11

1.00e-0338973PS00690
DomainAdipoR/HlyIII-related

ADIPOR1 ADIPOR2

1.42e-0311972IPR004254
DomainHlyIII

ADIPOR1 ADIPOR2

1.42e-0311972PF03006
DomainCyt_P450_E_grp-I

CYP4F2 CYP4F3 CYP4F11

1.65e-0345973IPR002401
DomainZnf_UBP

HDAC6 USP51

2.33e-0314972IPR001607
Domainzf-UBP

HDAC6 USP51

2.33e-0314972PF02148
DomainZF_UBP

HDAC6 USP51

2.33e-0314972PS50271
DomainCyt_P450_CS

CYP4F2 CYP4F3 CYP4F11

2.64e-0353973IPR017972
DomainCYTOCHROME_P450

CYP4F2 CYP4F3 CYP4F11

3.24e-0357973PS00086
Domain-

CYP4F2 CYP4F3 CYP4F11

3.41e-03589731.10.630.10
Domainp450

CYP4F2 CYP4F3 CYP4F11

3.41e-0358973PF00067
DomainCyt_P450

CYP4F2 CYP4F3 CYP4F11

3.75e-0360973IPR001128
DomainDSRM

PRKRA DROSHA

4.31e-0319972SM00358
Domaindsrm

PRKRA DROSHA

4.77e-0320972PF00035
PathwayKEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_VGCC_CA2_APOPTOTIC_PATHWAY

CACNA1C CACNA1D CACNA1F CACNA1S

1.36e-086794M47762
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_VGCC_CA2_APOPTOTIC_PATHWAY_N01004

CACNA1C CACNA1D CACNA1F CACNA1S

8.76e-0714794M47692
PathwayKEGG_MEDICUS_REFERENCE_VGCC_CA2_APOPTOTIC_PATHWAY

CACNA1C CACNA1D CACNA1F CACNA1S

7.46e-0623794M47666
PathwayKEGG_MEDICUS_REFERENCE_CA2_ENTRY_VOLTAGE_GATED_CA2_CHANNEL

CACNA1C CACNA1D CACNA1F CACNA1S

1.06e-0525794M47948
PathwayWP_EICOSANOID_METABOLISM_VIA_LIPOXYGENASES_LOX

CYP4F2 CYP4F3 CYP4F11 ALOX12

3.30e-0533794MM15963
PathwayPID_HDAC_CLASSI_PATHWAY

RANBP2 HDAC6 CHD3 CHD4 SSPOP

3.33e-0566795M101
PathwayREACTOME_EICOSANOIDS

CYP4F2 CYP4F3 CYP4F11

3.59e-0512793M27129
PathwayREACTOME_MISCELLANEOUS_SUBSTRATES

CYP4F2 CYP4F3 CYP4F11

3.59e-0512793M27128
PathwayREACTOME_EICOSANOIDS

CYP4F2 CYP4F3 CYP4F11

3.59e-0512793MM14845
PathwayWP_ALZHEIMERS_DISEASE

CACNA1C CACNA1D CACNA1F CACNA1S LRP1

5.79e-0574795MM15962
PathwayWP_EICOSANOID_METABOLISM_VIA_CYTOCHROME_P450_MONOOXYGENASES

CYP4F2 CYP4F3 CYP4F11

5.90e-0514793MM15842
PathwayREACTOME_FATTY_ACIDS

CYP4F2 CYP4F3 CYP4F11

7.34e-0515793M27126
PathwayKEGG_CARDIAC_MUSCLE_CONTRACTION

CACNA1C CACNA1D CACNA1F CACNA1S ATP1A4

7.93e-0579795M17673
PathwayREACTOME_MISCELLANEOUS_SUBSTRATES

CYP4F2 CYP4F3 CYP4F11

1.30e-0418793MM14843
PathwayREACTOME_FATTY_ACIDS

CYP4F2 CYP4F3 CYP4F11

1.30e-0418793MM14841
PathwayREACTOME_SYNTHESIS_OF_LEUKOTRIENES_LT_AND_EOXINS_EX

CYP4F2 CYP4F3 CYP4F11

2.09e-0421793M27137
PathwayREACTOME_ARACHIDONIC_ACID_METABOLISM

CYP4F2 CYP4F3 CYP4F11 ALOX12

3.29e-0459794M27140
PathwayREACTOME_SYNTHESIS_OF_LEUKOTRIENES_LT_AND_EOXINS_EX

CYP4F2 CYP4F3 CYP4F11

3.56e-0425793MM14858
PathwayREACTOME_ARACHIDONIC_ACID_METABOLISM

CYP4F2 CYP4F3 CYP4F11 ALOX12

3.74e-0461794MM14861
PathwayREACTOME_AMPK_INHIBITS_CHREBP_TRANSCRIPTIONAL_ACTIVATION_ACTIVITY

ADIPOR1 ADIPOR2

4.58e-046792MM14630
PathwayREACTOME_INTEGRATION_OF_ENERGY_METABOLISM

CACNA1C CACNA1D ADIPOR1 ADIPOR2

7.04e-0472794MM14631
PathwayKEGG_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY_ARVC

CACNA1C CACNA1D CACNA1F CACNA1S

7.81e-0474794M16376
PathwayWP_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY

CACNA1C CACNA1D CACNA1F CACNA1S

7.81e-0474794M39462
PathwayWP_EICOSANOID_METABOLISM_VIA_CYCLOOXYGENASES_COX

CYP4F2 CYP4F3 CYP4F11

8.19e-0433793MM15918
PathwayREACTOME_AMPK_INHIBITS_CHREBP_TRANSCRIPTIONAL_ACTIVATION_ACTIVITY

ADIPOR1 ADIPOR2

8.49e-048792M26990
PathwayKEGG_HYPERTROPHIC_CARDIOMYOPATHY_HCM

CACNA1C CACNA1D CACNA1F CACNA1S

1.20e-0383794M8728
PathwayWP_LEPTIN_AND_ADIPONECTIN

ADIPOR1 ADIPOR2

1.36e-0310792M39539
PathwayWP_LEPTIN_AND_ADIPONECTIN

ADIPOR1 ADIPOR2

1.36e-0310792MM15824
PathwayKEGG_DILATED_CARDIOMYOPATHY

CACNA1C CACNA1D CACNA1F CACNA1S

1.62e-0390794M835
PathwayBIOCARTA_RANBP2_PATHWAY

RANBP2 HDAC6

1.65e-0311792M22027
PathwayREACTOME_SYNTHESIS_OF_16_20_HYDROXYEICOSATETRAENOIC_ACIDS_HETE

CYP4F2 CYP4F11

1.65e-0311792MM14863
PathwayBIOCARTA_PTC1_PATHWAY

PTCH1 CDK7

1.65e-0311792M13022
PathwayKEGG_MEDICUS_REFERENCE_CA2_CAM_VGCC_RYR_SIGNALING_PATHWAY

CACNA1C CACNA1S

1.65e-0311792M47958
PathwayBIOCARTA_PTC1_PATHWAY

PTCH1 CDK7

1.65e-0311792MM1499
PathwayREACTOME_NCAM1_INTERACTIONS

CACNA1C CACNA1D CACNA1S

1.66e-0342793M7169
PathwayKEGG_NUCLEOTIDE_EXCISION_REPAIR

ERCC4 RFC2 CDK7

1.90e-0344793M18937
PathwayWP_NUCLEOTIDE_EXCISION_REPAIR

ERCC4 RFC2 CDK7

1.90e-0344793M39847
Pubmed

Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution.

ERVK-6 ERVK-21 ERVK-9 ERVK-8 ERVK-19 ERVFRD-1

5.30e-1312103614557543
Pubmed

Beta-adrenergic-regulated phosphorylation of the skeletal muscle Ca(V)1.1 channel in the fight-or-flight response.

CACNA1C CACNA1D CACNA1F CACNA1S

7.25e-114103420937870
Pubmed

Quantitation of HERV-K env gene expression and splicing in human breast cancer.

ERVK-6 ERVK-7 ERVK-21 ERVK-19

3.62e-105103412629516
Pubmed

Enhanced expression of L-type Cav1.3 calcium channels in murine embryonic hearts from Cav1.2-deficient mice.

CACNA1C CACNA1D CACNA1F CACNA1S

2.52e-097103412900400
Pubmed

A revised nomenclature for transcribed human endogenous retroviral loci.

ERVK-6 ERVK-7 ERVK-21 ERVK-9 ERVK-8 ERVK-19 ERVFRD-1

1.35e-0894103721542922
Pubmed

Survey of human genes of retroviral origin: identification and transcriptome of the genes with coding capacity for complete envelope proteins.

ERVK-6 ERVK-21 ERVK-19 ERVFRD-1

1.50e-0810103412970426
Pubmed

Impairment of hippocampal gamma-frequency oscillations in vitro in mice overexpressing human amyloid precursor protein (APP).

CACNA1C CACNA1D CACNA1S

2.52e-083103317767505
Pubmed

Molecular diversity of L-type calcium channels. Evidence for alternative splicing of the transcripts of three non-allelic genes.

CACNA1C CACNA1D CACNA1S

2.52e-08310332173707
Pubmed

Angiotensin II suppresses long-term depression in the lateral amygdala of mice via L-type calcium channels.

CACNA1C CACNA1D CACNA1S

2.52e-083103317289261
Pubmed

Voltage-activated calcium channel expression profiles in mouse brain and cultured hippocampal neurons.

CACNA1C CACNA1D CACNA1F CACNA1S

9.66e-0815103420188150
Pubmed

Differential neuronal targeting of a new and two known calcium channel β4 subunit splice variants correlates with their regulation of gene expression.

CACNA1C CACNA1D CACNA1F CACNA1S

9.66e-0815103424453333
Pubmed

Omega oxidation of 3-hydroxy fatty acids by the human CYP4F gene subfamily enzyme CYP4F11.

CYP4F2 CYP4F3 CYP4F11

1.01e-074103318065749
Pubmed

The cytochrome P450 4 (CYP4) family.

CYP4F2 CYP4F3 CYP4F11

5.01e-07610339068972
Pubmed

Human endogenous retrovirus HERV-K(HML-2) proviruses with Rec protein coding capacity and transcriptional activity.

ERVK-6 ERVK-9 ERVK-19

5.01e-076103315063128
Pubmed

Evolutionary insights into T-type Ca2+ channel structure, function, and ion selectivity from the Trichoplax adhaerens homologue.

CACNA1D CACNA1F CACNA1S

1.40e-068103328330839
Pubmed

International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels.

CACNA1C CACNA1F CACNA1S

2.09e-069103316382099
Pubmed

Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.

CACNA1C CACNA1D CACNA1F CACNA1S KCNH6 KCNJ2

3.80e-06139103616985003
Pubmed

NCAM induces CaMKIIalpha-mediated RPTPalpha phosphorylation to enhance its catalytic activity and neurite outgrowth.

CACNA1C CACNA1D CACNA1F

4.09e-0611103318809727
Pubmed

Cell cycle-related kinase is a crucial regulator for ciliogenesis and Hedgehog signaling in embryonic mouse lung development.

DYNC2H1 PTCH1 DNAH11 CDK7

6.11e-0640103432317081
Pubmed

Adiponectin receptor-1 expression is decreased in the pancreas of obese mice.

ADIPOR1 ADIPOR2

8.69e-062103219062045
Pubmed

Lack of any prognostic relationship between adiponectin receptor (Adipo R1/R2) expression for early/advanced stage gastric cancer.

ADIPOR1 ADIPOR2

8.69e-062103224969908
Pubmed

Temporal expression of calcium channel subunits in satellite cells and bone marrow mesenchymal cells.

CACNA1C CACNA1S

8.69e-062103225277766
Pubmed

Molecular analysis of a major antigenic region of the 240-kD protein of Mi-2 autoantigen.

CHD3 CHD4

8.69e-06210327560064
Pubmed

Arterial stiffness is associated with increased monocyte expression of adiponectin receptor mRNA and protein in patients with coronary artery disease.

ADIPOR1 ADIPOR2

8.69e-062103222534793
Pubmed

Omental fat expression of adiponectin and adiponectin receptors in non-obese women with PCOS: a preliminary study.

ADIPOR1 ADIPOR2

8.69e-062103219909601
Pubmed

The role of AdipoR1 and AdipoR2 in liver fibrosis.

ADIPOR1 ADIPOR2

8.69e-062103229237572
Pubmed

Variations in adiponectin receptor genes and susceptibility to type 2 diabetes in women: a tagging-single nucleotide polymorphism haplotype analysis.

ADIPOR1 ADIPOR2

8.69e-062103217416799
Pubmed

Adiponectin receptor expression predicts favorable prognosis in cases of hepatocellular carcinoma.

ADIPOR1 ADIPOR2

8.69e-062103224619866
Pubmed

A single nucleotide deletion in the skeletal muscle-specific calcium channel transcript of muscular dysgenesis (mdg) mice.

CACNA1C CACNA1S

8.69e-06210321281468
Pubmed

Involvement of AdipoR receptor in adiponectin-induced motility and alpha2beta1 integrin upregulation in human chondrosarcoma cells.

ADIPOR1 ADIPOR2

8.69e-062103219549705
Pubmed

Different roles attributed to Cav1 channel subtypes in spontaneous action potential firing and fine tuning of exocytosis in mouse chromaffin cells.

CACNA1C CACNA1D

8.69e-062103221054386
Pubmed

Pattern of expression of adiponectin receptors in human liver and its relation to nonalcoholic steatohepatitis.

ADIPOR1 ADIPOR2

8.69e-062103218923878
Pubmed

Dual action of adiponectin on insulin secretion in insulin-resistant mice.

ADIPOR1 ADIPOR2

8.69e-062103215358228
Pubmed

Regulation of adiponectin receptor gene expression in diabetic mice.

ADIPOR1 ADIPOR2

8.69e-062103215613685
Pubmed

Voltage-Gated Cav1 Channels in Disorders of Vision and Hearing.

CACNA1D CACNA1F

8.69e-062103225966695
Pubmed

AdipoR1 and AdipoR2 maintain membrane fluidity in most human cell types and independently of adiponectin.

ADIPOR1 ADIPOR2

8.69e-062103230890562
Pubmed

The major dermatomyositis-specific Mi-2 autoantigen is a presumed helicase involved in transcriptional activation.

CHD3 CHD4

8.69e-06210327575689
Pubmed

Genetic variations in genes involved in heparan sulphate biosynthesis are associated with Plasmodium falciparum parasitaemia: a familial study in Burkina Faso.

HS3ST3B1 HS3ST3A1

8.69e-062103222475533
Pubmed

The regulation of adiponectin receptors in human prostate cancer cell lines.

ADIPOR1 ADIPOR2

8.69e-062103216899222
Pubmed

An improved targeted cAMP sensor to study the regulation of adenylyl cyclase 8 by Ca2+ entry through voltage-gated channels.

CACNA1C CACNA1D

8.69e-062103224086669
Pubmed

Genetic analysis of the cytoplasmic dynein subunit families.

DYNC2H1 DYNC1H1

8.69e-062103216440056
Pubmed

Differential zinc permeation and blockade of L-type Ca2+ channel isoforms Cav1.2 and Cav1.3.

CACNA1C CACNA1D

8.69e-062103226049024
Pubmed

Characterisation of the adiponectin receptors: Differential cell-surface expression and temporal signalling profiles of AdipoR1 and AdipoR2 are regulated by the non-conserved N-terminal trunks.

ADIPOR1 ADIPOR2

8.69e-062103225892445
Pubmed

Adiponectin receptors form homomers and heteromers exhibiting distinct ligand binding and intracellular signaling properties.

ADIPOR1 ADIPOR2

8.69e-062103223255609
Pubmed

Polymorphisms in adiponectin receptor genes ADIPOR1 and ADIPOR2 and insulin resistance.

ADIPOR1 ADIPOR2

8.69e-062103217716299
Pubmed

Low-abundant adiponectin receptors in visceral adipose tissue of humans and rats are further reduced in diabetic animals.

ADIPOR1 ADIPOR2

8.69e-062103220470935
Pubmed

Adipo-R1 and adipo-R2 expression in colorectal adenomas and carcinomas.

ADIPOR1 ADIPOR2

8.69e-062103225640382
Pubmed

The expression and relationship of AdipoR1/R2 in gastric intestinal metaplasia.

ADIPOR1 ADIPOR2

8.69e-062103233851685
Pubmed

Adiponectin receptor expression is elevated in colorectal carcinomas but not in gastrointestinal stromal tumors.

ADIPOR1 ADIPOR2

8.69e-062103218310295
Pubmed

The effect of renal transplantation on adiponectin and its isoforms and receptors.

ADIPOR1 ADIPOR2

8.69e-062103217697862
Pubmed

Genetic polymorphisms of L-type calcium channel alpha1C and alpha1D subunit genes are associated with sensitivity to the antihypertensive effects of L-type dihydropyridine calcium-channel blockers.

CACNA1C CACNA1D

8.69e-062103219225208
Pubmed

Ca1.2 and CaV1.3 neuronal L-type calcium channels: differential targeting and signaling to pCREB.

CACNA1C CACNA1D

8.69e-062103216706838
Pubmed

Temperature-sensitive Cav1.2 calcium channels support intrinsic firing of pyramidal neurons and provide a target for the treatment of febrile seizures.

CACNA1C CACNA1D

8.69e-062103223761887
Pubmed

Polymorphisms of ADIPOR1 and ADIPOR2 are associated with phenotypes of type 2 diabetes in Koreans.

ADIPOR1 ADIPOR2

8.69e-062103218466348
Pubmed

Association of ADIPOR2 with liver function tests in type 2 diabetic subjects.

ADIPOR1 ADIPOR2

8.69e-062103218719649
Pubmed

Non-voltage-gated L-type Ca2+ channels in human T cells: pharmacology and molecular characterization of the major alpha pore-forming and auxiliary beta-subunits.

CACNA1C CACNA1D

8.69e-062103214981074
Pubmed

Adiponectin receptors are expressed in hypothalamus and colocalized with proopiomelanocortin and neuropeptide Y in rodent arcuate neurons.

ADIPOR1 ADIPOR2

8.69e-062103218971219
Pubmed

CaV1.2 and CaV1.3 channel hyperactivation in mouse islet β cells exposed to type 1 diabetic serum.

CACNA1C CACNA1D

8.69e-062103225292336
Pubmed

Crystal structures of the human adiponectin receptors.

ADIPOR1 ADIPOR2

8.69e-062103225855295
Pubmed

Adiponectin receptors gene expression and insulin sensitivity in non-diabetic Mexican Americans with or without a family history of Type 2 diabetes.

ADIPOR1 ADIPOR2

8.69e-062103215105989
Pubmed

Ca(v)1.3 channels produce persistent calcium sparklets, but Ca(v)1.2 channels are responsible for sparklets in mouse arterial smooth muscle.

CACNA1C CACNA1D

8.69e-062103217526649
Pubmed

Adiponectin receptors are downregulated in human gastric cancer.

ADIPOR1 ADIPOR2

8.69e-062103220336470
Pubmed

Mechanisms Responsible for ω-Pore Currents in Cav Calcium Channel Voltage-Sensing Domains.

CACNA1D CACNA1S

8.69e-062103228978442
Pubmed

Ligand-activated signal transduction in the 2-cell embryo.

CACNA1C CACNA1D

8.69e-062103212606379
Pubmed

Localization of chi1-related helicase genes to human chromosome regions 12p11 and 12p13: similarity between parts of these genes and conserved human telomeric-associated DNA.

DDX12P DDX11

8.69e-06210328833153
Pubmed

Pyrimidine-2,4,6-triones are a new class of voltage-gated L-type Ca2+ channel activators.

CACNA1C CACNA1D

8.69e-062103224941892
Pubmed

Structural insights into adiponectin receptors suggest ceramidase activity.

ADIPOR1 ADIPOR2

8.69e-062103228329765
Pubmed

Localization of novel adiponectin receptor constructs.

ADIPOR1 ADIPOR2

8.69e-062103217118803
Pubmed

in vitro Anti-Proliferative Effect of Adiponectin on Human Endometriotic Stromal Cells through AdipoR1 and AdipoR2 Gene Receptor Expression.

ADIPOR1 ADIPOR2

8.69e-062103226459399
Pubmed

A monoclonal antibody activating AdipoR for type 2 diabetes and nonalcoholic steatohepatitis.

ADIPOR1 ADIPOR2

8.69e-062103237948516
Pubmed

AdipoR1 and 2 are expressed on warm sensitive neurons of the hypothalamic preoptic area and contribute to central hyperthermic effects of adiponectin.

ADIPOR1 ADIPOR2

8.69e-062103222000082
Pubmed

Adiponectin regulate growth hormone secretion via adiponectin receptor mediated Ca(2+) signalling in rat somatotrophs in vitro.

ADIPOR1 ADIPOR2

8.69e-062103219500219
Pubmed

Regulation of adiponectin receptors in hepatocytes by the peroxisome proliferator-activated receptor-gamma agonist rosiglitazone.

ADIPOR1 ADIPOR2

8.69e-062103216609881
Pubmed

Equal sensitivity of Cav1.2 and Cav1.3 channels to the opposing modulations of PKA and PKG in mouse chromaffin cells.

CACNA1C CACNA1D

8.69e-062103222826131
Pubmed

C-terminal modulator controls Ca2+-dependent gating of Ca(v)1.4 L-type Ca2+ channels.

CACNA1D CACNA1F

8.69e-062103216921373
Pubmed

Transcriptional regulation of L-type calcium channel subtypes Cav1.2 and Cav1.3 by nicotine and their potential role in nicotine sensitization.

CACNA1C CACNA1D

8.69e-062103224470632
Pubmed

The distribution of adiponectin receptors on human peripheral blood mononuclear cells.

ADIPOR1 ADIPOR2

8.69e-062103219120283
Pubmed

Role of adiponectin receptors, AdipoR1 and AdipoR2, in the steroidogenesis of the human granulosa tumor cell line, KGN.

ADIPOR1 ADIPOR2

8.69e-062103219671624
Pubmed

Cav1.2 and Cav1.3 L-type calcium channels operate in a similar voltage range but show different coupling to Ca(2+)-dependent conductances in hippocampal neurons.

CACNA1C CACNA1D

8.69e-062103224760982
Pubmed

Leveraging a gain-of-function allele of Caenorhabditis elegans paqr-1 to elucidate membrane homeostasis by PAQR proteins.

ADIPOR1 ADIPOR2

8.69e-062103232750056
Pubmed

Genetic variation in adiponectin receptor 1 and adiponectin receptor 2 is associated with type 2 diabetes in the Old Order Amish.

ADIPOR1 ADIPOR2

8.69e-062103215983228
Pubmed

Cardiomyocyte-derived adiponectin is biologically active in protecting against myocardial ischemia-reperfusion injury.

ADIPOR1 ADIPOR2

8.69e-062103220028965
Pubmed

Deletion of the L-type calcium channel Ca(V) 1.3 but not Ca(V) 1.2 results in a diminished sAHP in mouse CA1 pyramidal neurons.

CACNA1C CACNA1D

8.69e-062103220014384
Pubmed

Adiponectin and adiponectin receptor in relation to colorectal cancer progression.

ADIPOR1 ADIPOR2

8.69e-062103221351255
Pubmed

Cytochrome P450-dependent catabolism of vitamin K: ω-hydroxylation catalyzed by human CYP4F2 and CYP4F11.

CYP4F2 CYP4F11

8.69e-062103224138531
Pubmed

Expression of adiponectin receptor mRNA in human skeletal muscle cells is related to in vivo parameters of glucose and lipid metabolism.

ADIPOR1 ADIPOR2

8.69e-062103215331527
Pubmed

Muscle-specific overexpression of AdipoR1 or AdipoR2 gives rise to common and discrete local effects whilst AdipoR2 promotes additional systemic effects.

ADIPOR1 ADIPOR2

8.69e-062103228145500
Pubmed

Role of putative voltage-sensor countercharge D4 in regulating gating properties of CaV1.2 and CaV1.3 calcium channels.

CACNA1C CACNA1D

8.69e-062103230001160
Pubmed

AdipoR agonist increases insulin sensitivity and exercise endurance in AdipoR-humanized mice.

ADIPOR1 ADIPOR2

8.69e-062103233420419
Pubmed

Rescue and worsening of congenital heart block-associated electrocardiographic abnormalities in two transgenic mice.

CACNA1C CACNA1D

8.69e-062103221352396
Pubmed

Overexpression of adiponectin receptors potentiates the antiinflammatory action of subeffective dose of globular adiponectin in vascular endothelial cells.

ADIPOR1 ADIPOR2

8.69e-062103218988888
Pubmed

Cloning and expression of a novel form of leukotriene B4 omega-hydroxylase from human liver.

CYP4F2 CYP4F3

8.69e-06210328026587
Pubmed

Chromosomal mapping of two members of the human dynein gene family to chromosome regions 7p15 and 11q13 near the deafness loci DFNA 5 and DFNA 11.

DYNC2H1 DNAH11

8.69e-06210329325061
Pubmed

Molecular nature of anomalous L-type calcium channels in mouse cerebellar granule cells.

CACNA1C CACNA1D

8.69e-062103217409250
Pubmed

Neuronal L-type calcium channels open quickly and are inhibited slowly.

CACNA1C CACNA1D

8.69e-062103216267232
Pubmed

Macrophage polarization phenotype regulates adiponectin receptor expression and adiponectin anti-inflammatory response.

ADIPOR1 ADIPOR2

8.69e-062103225392268
Pubmed

Absence of an association between the polymorphisms in the genes encoding adiponectin receptors and type 2 diabetes.

ADIPOR1 ADIPOR2

8.69e-062103215918014
Pubmed

The adiponectin receptors AdipoR1 and AdipoR2 activate ERK1/2 through a Src/Ras-dependent pathway and stimulate cell growth.

ADIPOR1 ADIPOR2

8.69e-062103218842004
Pubmed

Expression of human endogenous retrovirus type K envelope glycoprotein in insect and mammalian cells.

ERVK-6 ERVK-19

8.69e-06210329060628
Pubmed

The role of L-type voltage-gated calcium channels Cav1.2 and Cav1.3 in normal and pathological brain function.

CACNA1C CACNA1D

8.69e-062103224996399
GeneFamilyCalcium voltage-gated channel subunits

CACNA1C CACNA1D CACNA1F CACNA1S

2.89e-0626704253
GeneFamilyAdiponectin receptors|Progestin and adipoQ receptor family

ADIPOR1 ADIPOR2

1.48e-052702293
GeneFamilyCytochrome P450 family 4

CYP4F2 CYP4F3 CYP4F11

3.62e-04367031003
GeneFamilyProgestin and adipoQ receptor family

ADIPOR1 ADIPOR2

7.95e-0411702930
GeneFamilyPHD finger proteins|NuRD complex

CHD3 CHD4

9.51e-04127021305
GeneFamilyDyneins, cytoplasmic

DYNC2H1 DYNC1H1

1.12e-0313702538
GeneFamilyZinc fingers RANBP2-type |RNA binding motif containing

RANBP2 ZRANB3

2.96e-032170289
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRHDE CACNA1F SFI1 SSPOP PKHD1L1 ATP1A4 DNAH11

1.61e-071849772cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRHDE CACNA1F SFI1 SSPOP PKHD1L1 ATP1A4 DNAH11

1.61e-07184977ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRHDE CACNA1F SFI1 SSPOP PKHD1L1 ATP1A4 DNAH11

1.61e-071849772b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellControl-Stromal_mesenchymal|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TRHDE CACNA1C CACNA1D TRABD2B PTCH1 LRP1 HS3ST3A1

2.07e-0719197714057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DRC7 SSPOP KCNH6 USP51 FKTN DNAH11

2.42e-061769763766e0533b103ec92ac75eba3df02e287efc53fa
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-late_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DRC7 SSPOP KCNH6 USP51 FKTN DNAH11

2.42e-06176976aa1bada2175d8370fc71939a607407155259d195
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1C CACNA1D TRABD2B PTCH1 LRP1 HS3ST3A1

3.65e-0618997645e588b2a4ad9e3ff74e22d9d627ed3571f3b8b8
ToppCellTCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

MIOX CYP4F2 KCNH6 SLC22A6 CYP4F3

2.20e-0515497589a60a79d07466d7ad05888d10a72d3b1ab384af
ToppCellTCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal-Connective_tissue_normal|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

MIOX CYP4F2 KCNH6 SLC22A6 CYP4F3

2.20e-05154975f1fea1a87e977221fa125b62287368be9af4987d
ToppCellTCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal-Connective_tissue_normal-Connective_tissue_normal|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

MIOX CYP4F2 KCNH6 SLC22A6 CYP4F3

2.20e-05154975b5604c0b0b9b283352a3f612f40883b9123475d1
ToppCellTCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal-Connective_tissue_normal-Connective_tissue_normal-1|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

MIOX CYP4F2 KCNH6 SLC22A6 CYP4F3

2.20e-05154975160b170a3ade8b246843c9854af332475c047ba0
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BDKRB1 ZRANB3 IGSF9 DNAH11 SP7

2.57e-051599757ed659163f45e0c4df4782997c0786900c8186c8
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TRABD2B MIOX KCNH6 SLC22A6 CYP4F3

3.84e-051739758888434641ea554a9b62c436e87920378eef29cd
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TMC1 KCNH6 SLC22A6 PEBP1 CYP4F3

4.52e-0517997578fae47ec9bff4e0159a86a281e831d7f8ee925a
ToppCellChildren_(3_yrs)-Mesenchymal-myofibroblast_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

CACNA1C TRABD2B PTCH1 SEMA6D HS3ST3A1

4.64e-0518097501f2e5d96016823482f89ba503d007d4bd88eeac
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HDAC6 MIOX CYP4F2 SLC22A6 CYP4F3

5.02e-05183975facd6dbe0851b537d70a899ac7485714ab27d071
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1D TRABD2B PTCH1 LRP1 HS3ST3A1

5.02e-051839757eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MIOX KCNH6 SLC22A6 CYP4F3 PROC

5.02e-0518397585446581999cd66b171c4f69b7eb8b0bbbaa8617
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TRABD2B MIOX SLC22A6 TMEM132E CYP4F3

5.42e-051869755784d255e9ca449d375d81938d0fbbd8a7eb44f6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRABD2B MIOX KCNH6 SLC22A6 CYP4F3

5.56e-05187975dcf6475ece5b34d9d58a0d1f51c18acedb19c119
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRABD2B MIOX KCNH6 SLC22A6 CYP4F3

5.56e-05187975f1356273bd3587b6883295edf15cb9cdb706c057
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CACNA1C TRABD2B PTCH1 SEMA6D HS3ST3A1

5.56e-05187975c104fbfef2d0bef64077ac721edf2379fd59d547
ToppCellMesenchymal-myofibroblast_cell|World / Lineage, Cell type, age group and donor

CACNA1C TRABD2B PTCH1 SEMA6D HS3ST3A1

5.85e-0518997544e37f88137bb249933eb615235b2cf2ae7f3925
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TRHDE CACNA1C CACNA1D PTCH1 LRP1

5.85e-051899752a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1C CACNA1D TRABD2B PTCH1 HS3ST3A1

6.15e-05191975b133ee1c0e58d00ddd2e4e05b01fd04947524c18
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CACNA1C TRABD2B PTCH1 SEMA6D HS3ST3A1

6.30e-0519297572881b280a415e65f87a80ca1369cbb0b722a0c4
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1D HDAC6 DYNC2H1 CHD4 DYNC1H1

6.78e-051959753e519cffa6144a62b06124642a14c9ff39b76554
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1D HDAC6 DYNC2H1 CHD4 DYNC1H1

6.78e-051959757796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CACNA1D TRABD2B H6PD ANKRD13A LRP1

6.94e-05196975617103f4a09e009fe96c28eb5e40505a4fd6dcf4
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CACNA1D TRABD2B H6PD ANKRD13A LRP1

6.94e-05196975db64ab27374f82553ee577aec056141170f3656f
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CACNA1D H6PD SESN1 ANKRD13A LRP1

7.11e-0519797506a0d7062dadda656decaf77dcef9a10b5f2698d
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CACNA1D H6PD SESN1 ANKRD13A LRP1

7.11e-05197975d35c7a36135b5ed6a7bf2f934849678eba2a0177
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

TRHDE CACNA1D DYNC2H1 PTCH1 LRP1

7.64e-052009759b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCellBronchial-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TRHDE CACNA1C TRABD2B LRP1 HS3ST3A1

7.64e-05200975389cc775c8419d90fb77cd794376d2160a7bf44e
ToppCellSepsis-ICU-NoSEP-Lymphocyte-T/NK-MAIT|ICU-NoSEP / Disease, condition lineage and cell class

CACNA1D ERCC4 SESN1 USP51 METTL16

7.64e-052009754f03b5f4110ed1637ffe17cb6ff309265a3af9a8
DrugCinnarizine

CACNA1C CACNA1D CACNA1F CACNA1S

4.00e-089984DB00568
DrugNimodipine

CACNA1C CACNA1D CACNA1F CACNA1S

4.00e-089984DB00393
DrugMibefradil

CACNA1C CACNA1D CACNA1F CACNA1S

1.04e-0711984DB01388
DrugVerapamil

CACNA1C CACNA1D CACNA1F CACNA1S

5.64e-0716984DB00661
DrugNisoldipine

CACNA1C CACNA1D CACNA1S

7.68e-075983DB00401
DrugNilvadipine

CACNA1C CACNA1D CACNA1S

7.68e-075983DB06712
DrugCPU-23

CACNA1C CACNA1D CACNA1S

1.53e-066983CID003036051
DrugAmlodipine

CACNA1C CACNA1D CACNA1S

2.67e-067983DB00381
DrugIsradipine

CACNA1C CACNA1D CACNA1S

2.67e-067983DB00270
DrugNifedipine

CACNA1C CACNA1D CACNA1S

4.26e-068983DB01115
DrugNitrendipine

CACNA1C CACNA1D CACNA1S

4.26e-068983DB01054
Druglercanidipine

CACNA1C CACNA1D CACNA1F CACNA1S BDKRB1

7.69e-0663985CID000065866
Drugfelodipine

CACNA1C CACNA1D CACNA1F CACNA1S CYP4F2 CYP4F3 CYP4F11

8.60e-06169987CID000003333
DrugCNS 1145

CACNA1C CACNA1D CACNA1F CACNA1S

1.20e-0533984CID000190902
DrugIHC-64

CACNA1C CACNA1D CACNA1F CACNA1S

1.20e-0533984CID000162753
DrugFelodipine

CACNA1C CACNA1D CACNA1S

1.24e-0511983DB01023
Drugethosuximide

CACNA1C CACNA1D CACNA1F CACNA1S PTCH1

1.70e-0574985CID000003291
DrugRA 56

ACHE RIOX2

1.83e-052982CID005746926
DrugAC1O4QX2

ACHE RIOX2

1.83e-052982CID006399062
DrugNatamycin [7681-93-8]; Up 200; 6uM; MCF7; HT_HG-U133A

CACNA1D BDKRB1 SEMA6D KCNJ2 NME5 CYP4F3 ALOX12

2.40e-051989873548_UP
DrugAC1L1JG6

CACNA1C CACNA1D CACNA1S

2.72e-0514983CID000005026
DrugFPL 64176

CACNA1C CACNA1D CACNA1S

3.39e-0515983CID000003423
DrugAC1L1WTA

ACHE RIOX2

5.49e-053982CID000011190
DrugKW-3049

CACNA1C CACNA1D CACNA1F CACNA1S

6.38e-0550984CID000002324
Drugazelnidipine

CACNA1C CACNA1D TYK2 DYNC1H1

6.91e-0551984CID000065948
Drugparaoxon

ACHE CYP4F2 H6PD RIOX2 CYP4F3 CYP4F11

7.76e-05164986CID000009395
DiseaseTimothy syndrome (implicated_via_orthology)

CACNA1C CACNA1D CACNA1F CACNA1S

1.01e-104954DOID:0060173 (implicated_via_orthology)
DiseaseDuchenne muscular dystrophy (implicated_via_orthology)

CACNA1C CACNA1D CACNA1F CACNA1S

5.49e-0636954DOID:11723 (implicated_via_orthology)
DiseaseWarsaw breakage syndrome (implicated_via_orthology)

DDX12P DDX11

3.07e-053952DOID:0060535 (implicated_via_orthology)
Diseaseepilepsy (implicated_via_orthology)

BDKRB1 KCNH6 LRP1 ATP1A4 DYNC1H1

1.88e-04163955DOID:1826 (implicated_via_orthology)
DiseaseMuscular Dystrophy

ACHE FKTN

2.84e-048952C0026850
Diseasehexadecenedioate (C16:1-DC) measurement

CYP4F2 CYP4F11

3.64e-049952EFO_0800562
DiseaseShortened QT interval

CACNA1C KCNJ2

5.54e-0411952C0151879
DiseaseBasal cell carcinoma

ERCC4 PTCH1

5.54e-0411952C0007117
Diseasehypertension (biomarker_via_orthology)

HDAC6 CYP4F2 BDKRB1 CYP4F11 ALOX12

8.52e-04227955DOID:10763 (biomarker_via_orthology)
Diseasehyperinsulinism (biomarker_via_orthology)

ADIPOR1 ADIPOR2

1.05e-0315952DOID:2018 (biomarker_via_orthology)
DiseaseConventional (Clear Cell) Renal Cell Carcinoma

ACHE PIDD1 PEBP1 KDM6A

1.36e-03148954C0279702
Diseasewellbeing measurement

TRHDE ERCC4 ZKSCAN8 LINGO2 PTCH1 SEMA6D PEBP1 HS3ST3B1

1.78e-03692958EFO_0007869
Diseasecerebellum white matter volume change measurement, age at assessment

TRHDE LINGO2

1.88e-0320952EFO_0008007, EFO_0021498
DiseaseDeep Vein Thrombosis

F13B PROC

2.07e-0321952C0149871
DiseaseVenous Thrombosis

F13B PROC

2.07e-0321952C0042487
DiseaseSchizophrenia

CACNA1C CACNA1F ACHE CHD4 KCNH6 ERVK-8 LRP1 ZNF480 ALOX12

2.19e-03883959C0036341
DiseaseCardiac Arrhythmia

CACNA1C KCNJ2

2.93e-0325952C0003811
Diseasecolon adenocarcinoma (is_implicated_in)

CHD4 KDM6A

3.17e-0326952DOID:234 (is_implicated_in)
Diseasemigraine disorder, pulse pressure measurement

DYNC2H1 LRP1

3.17e-0326952EFO_0005763, MONDO_0005277

Protein segments in the cluster

PeptideGeneStartEntry
EHHRITYLDKGSWLL

TRHDE

666

Q9UKU6
LHYTDWLHPEDPARL

ACHE

411

P22303
GVKYAAELHLVHWNP

CA3

111

P07451
LIRKGIPHHFRAIVW

EVI5L

111

Q96CN4
LLLPHEAWHFARIVE

BDKRB1

191

P46663
HLWLHESARVYGDKL

DNAH11

2736

Q96DT5
WVEKHVGSPAHLAYR

ACOT12

391

Q8WYK0
LPDRLKWYLLSEHSG

ASB6

401

Q9NWX5
HLAGQWEKHRVPLLA

CCDC22

416

O60826
WEKHRVPLLAEYRHL

CCDC22

421

O60826
WRAILPAKIAHEHFL

ASPM

3011

Q8IZT6
KDEIRHWILPQDYDH

RCN1

266

Q15293
EKHGLQPALLVHWAE

RANBP2

566

P49792
RLWIGNLDPKITEYH

RBM18

26

Q96H35
LPDWLKDNDFLLHGH

ADIPOR2

111

Q86V24
HPAGHLVLKWLIEQD

PUM3

551

Q15397
LWGHRYEPVLFEEKH

KCNJ2

321

P63252
DAGDHYPLHLLVWKN

ANKRD13A

6

Q8IZ07
YLTRDWSILGPHHLD

CACNA1F

1446

O60840
WSILGPHHLDEFKRI

CACNA1F

1451

O60840
AARFGHPVLVEWLLH

ESPNL

111

Q6ZVH7
PDWLKDNDYLLHGHR

ADIPOR1

101

Q96A54
IQIGIYAKHLEHWLR

HS3ST3B1

271

Q9Y662
HLIYGEPRKLLTQDW

MAGEA10

261

P43363
DEGAKHIWNALPHLR

NLRP8

881

Q86W28
GLVVHPLRGKLYWTD

LRP1

1706

Q07954
EIIWHGRTKEEPAHY

KDM6A

1316

O15550
ERPYLEHKIGWLDSL

KCNH6

426

Q9H252
LKWDFDNRPHILHGE

F13B

596

P05160
RKDPKYREWHHFLVV

PEBP1

76

P30086
RHKAISYWLELLGPN

NME5

86

P56597
LRLNYIHWVEDLIGH

METTL16

81

Q86W50
HLKHLEIDYWPLLDM

LINGO2

226

Q7L985
IQIGIYAKHLEHWLR

HS3ST3A1

286

Q9Y663
PGALYAHDALRLWEI

ALOX12

456

P18054
EYLRQVHAHWEKGGL

DDX11

711

Q96FC9
IDRHLGEPHKFKREW

INSIG2

91

Q9Y5U4
YLDWIHGHIRDKEAP

PROC

441

P04070
DWYHRIDPTVLLGAL

PTPMT1

36

Q8WUK0
LDSIAHGHRLIPYDW

ERVK-19

336

Q9YNA8
HGHRLIPYDWEILAK

ERVK-19

341

Q9YNA8
LDSIAHGHRLIPYDW

ERVK-21

336

P62683
HGHRLIPYDWEILAK

ERVK-21

341

P62683
LDSIAHGHRLIPYDW

ERVK-6

336

Q7LDI9
HGHRLIPYDWEILAK

ERVK-6

341

Q7LDI9
LDSIAHGHRLIPYDW

ERVK-7

336

P63130
HGHRLIPYDWEILAK

ERVK-7

341

P63130
LDSIAHGHRLIPYDW

ERVK-8

336

P62685
HGHRLIPYDWEILAK

ERVK-8

341

P62685
LDSIAHGHRLIPYDW

ERVK-9

336

P63126
HGHRLIPYDWEILAK

ERVK-9

341

P63126
LDSIAHGHRLIPYDW

HERVK_113

336

P62684
HGHRLIPYDWEILAK

HERVK_113

341

P62684
ILKYVRGEHLSPDHW

DYNC2H1

1196

Q8NCM8
ILGPHHLDEFKRIWA

CACNA1C

1536

Q13936
YLTRDWSILGPHHLD

CACNA1S

1386

Q13698
WSILGPHHLDEFKAI

CACNA1S

1391

Q13698
EYLHQHWILHRDLKP

CDK7

126

P50613
ENVDPDYWEKLLRHH

CHD3

1311

Q12873
GLSWVLYHLAKHPEY

CYP4F11

336

Q9HBI6
VHWFRKGLRLHDNPA

CRY1

6

Q16526
WIHRHPKAEDLRVGL

FSCN3

6

Q9NQT6
YLRQVHAHWEKGGLL

DDX12P

731

Q92771
GLSWVLYHLAKHPEY

CYP4F2

336

P78329
GNYLWHGHLRLKEHI

FKTN

181

O75072
AKPDALHGLRVHSWV

DRC7

291

Q8IY82
RHEALLYTWLAEHKP

DYNC1H1

2576

Q14204
VEVLGHLPKRFSWFH

KHDC3L

21

Q587J8
GLSWVLYHLAKHPEY

CYP4F3

336

Q08477
ARPHLAVIGLDAYLW

EME2

176

A4GXA9
GDADYLAAWHRLVLP

HDAC6

711

Q9UBN7
AWLRVVLEKPFGHDH

H6PD

166

O95479
GHVHYLIKWRDLPYD

CHD4

636

Q14839
WHHHDKDGRPLYVLR

SEC14L1

331

Q92503
LLAGVAYAVPHWRHL

SLC22A6

236

Q4U2R8
IPHGYLAILSEAKWV

SLFN13

756

Q68D06
ILGPHHLDEFKRIWS

CACNA1D

1476

Q01668
LDWPAVALHLGVSYR

PIDD1

801

Q9HB75
PDKDWFHLVGLLHDL

MIOX

111

Q9UGB7
ALGWKAVERVLYPHL

TAF6L

316

Q9Y6J9
ELLPLLHAAWDHYRI

SFI1

436

A8K8P3
KKAHPDRLHDELWYN

DROSHA

511

Q9NRR4
LAHRPWLITKEHIEG

SESN1

171

Q9Y6P5
GLHWHDYRDLLPGIL

SSPOP

2161

A2VEC9
KDLYGPDNHLVEWHR

SMARCD1

246

Q96GM5
WHIDYRGHGALPDLE

TMEM132E

411

Q6IEE7
IRPHRPEWVHDKADY

PTCH1

941

Q13635
HKFPHVRQLESLGWD

SPATA25

91

Q9BR10
FRVLLWGPAAVEHHK

URB1

1561

O60287
LDSIAHGHRLIPYDW

ERVK-9

336

P63128
HGHRLIPYDWEILAK

ERVK-9

341

P63128
EDYHPLIALKWLLGR

TMC1

431

Q8TDI8
PVDLLGIRLHWEDKY

ATP1A4

886

Q13733
LARHWRVHTGEKPYK

ZNF665

501

Q9H7R5
LHYSEWHRKKQAGIP

TRAPPC1

16

Q9Y5R8
HIPYKLLHLIWIHAE

USP51

426

Q70EK9
ELHISYRWDPNLKGL

ERVFRD-1

71

P60508
LKAHLRWHTGERPFV

SP7

311

Q8TDD2
DVLPHELYWRLKRHL

TRABD2B

111

A6NFA1
VPRHHRGEIWKFLAE

TBC1D1

801

Q86TI0
KPLHYISWLVGHEGK

NRDC

456

O43847
ILAHLWHLGYSPEDI

RFC2

281

P35250
LGRYPIHWHLLGDLQ

PKHD1L1

2471

Q86WI1
LILRPLTKEAHGHWE

IGSF9

471

Q9P2J2
ERYWGRLLHKLEHEV

TTLL12

46

Q14166
EGEKHWRLYHPTVPL

RIOX2

191

Q8IUF8
LQELAIHHGWRLPEY

PRKRA

131

O75569
LAQHWRIHTGEKPYK

ZNF480

386

Q8WV37
LNDHWRLHTGEKPYE

ZNF154

176

Q13106
PFDKTIRHYLDPLWH

ERCC4

261

Q92889
IRHYLDPLWHQLGAK

ERCC4

266

Q92889
GDWDILILHYLGLDH

PIGG

206

Q5H8A4
KWIKEPHFLHAIEYG

SEMA6D

216

Q8NFY4
LIYHLEHGQEPWTRK

ZNF805

61

Q5CZA5
GLVRHWRIHTGEKPY

ZKSCAN8

336

Q15776
QAKLRPEDGLYLIHW

TYK2

461

P29597
HVVFAELYWDPGHIK

ZRANB3

411

Q5FWF4