Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainG8

PKHD1 PKHD1L1

4.37e-054512PF10162
DomainG8_domain

PKHD1 PKHD1L1

4.37e-054512IPR019316
DomainG8

PKHD1 PKHD1L1

4.37e-054512PS51484
DomainG8

PKHD1 PKHD1L1

4.37e-054512SM01225
DomainIPT

PKHD1 NFAT5 PKHD1L1

5.36e-0527513SM00429
DomainVWC

COL5A2 PXDN MUC5AC

5.99e-0528513PF00093
DomainTIG

PKHD1 NFAT5 PKHD1L1

8.17e-0531513PF01833
DomainIPT

PKHD1 NFAT5 PKHD1L1

9.00e-0532513IPR002909
DomainPbH1

PKHD1 PKHD1L1

1.09e-046512SM00710
DomainPbH1

PKHD1 PKHD1L1

1.09e-046512IPR006626
DomainVWFC_1

COL5A2 PXDN MUC5AC

1.29e-0436513PS01208
DomainVWC

COL5A2 PXDN MUC5AC

1.51e-0438513SM00214
DomainVWFC_2

COL5A2 PXDN MUC5AC

1.51e-0438513PS50184
DomainIg_E-set

CD109 PKHD1 NFAT5 PKHD1L1

1.85e-04104514IPR014756
DomainPectin_lyase_fold/virulence

PKHD1 PKHD1L1

2.03e-048512IPR011050
DomainVWF_dom

COL5A2 PXDN MUC5AC

2.04e-0442513IPR001007
DomainPeptidase_M14

AGBL1 AGTPBP1

1.78e-0323512PF00246
DomainPeptidase_M14

AGBL1 AGTPBP1

1.78e-0323512IPR000834
Domain-

CNTNAP2 ADGRD1 PROS1

2.22e-03955132.60.120.200
DomainSerpin_CS

SERPINB2 SERPINA6

3.44e-0332512IPR023795
DomainSerpin_dom

SERPINB2 SERPINA6

4.34e-0336512IPR023796
DomainSERPIN

SERPINB2 SERPINA6

4.58e-0337512SM00093
DomainSERPIN

SERPINB2 SERPINA6

4.58e-0337512PS00284
DomainSerpin

SERPINB2 SERPINA6

4.83e-0338512PF00079
DomainLAM_G_DOMAIN

CNTNAP2 PROS1

4.83e-0338512PS50025
DomainSerpin_fam

SERPINB2 SERPINA6

5.08e-0339512IPR000215
DomainLaminin_G_2

CNTNAP2 PROS1

5.34e-0340512PF02210
DomainLamG

CNTNAP2 PROS1

6.43e-0344512SM00282
DomainLaminin_G

CNTNAP2 PROS1

1.10e-0258512IPR001791
DomainBACK

BTBD6 KBTBD12

1.17e-0260512SM00875
DomainBACK

BTBD6 KBTBD12

1.21e-0261512PF07707
Pubmed

[Effect of osmotic response element binding protein on mucus secretion with hypertonicity in human airway epithelial cells].

NFAT5 MUC5AC

6.32e-06351221418859
Pubmed

Reduced transcript expression of genes affected by inherited and de novo CNVs in autism.

CNTNAP2 PRODH

1.26e-05451221448237
Pubmed

The cytoplasmic tail of fibrocystin contains a ciliary targeting sequence.

PKHD1 PKHD1L1

2.10e-05551220048263
Pubmed

The cytosolic carboxypeptidases CCP2 and CCP3 catalyze posttranslational removal of acidic amino acids.

AGBL1 AGTPBP1

3.15e-05651225103237
Pubmed

The carboxypeptidase-like substrate-binding site in Nna1 is essential for the rescue of the Purkinje cell degeneration (pcd) phenotype.

AGBL1 AGTPBP1

3.15e-05651216952463
Pubmed

A novel subfamily of mouse cytosolic carboxypeptidases.

AGBL1 AGTPBP1

3.15e-05651217244818
Pubmed

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.

COL5A2 PXDN CD109 IL1RAP PROS1

3.18e-0524851524006456
Pubmed

A family of protein-deglutamylating enzymes associated with neurodegeneration.

AGBL1 AGTPBP1

4.41e-05751221074048
Pubmed

Arf4 is required for Mammalian development but dispensable for ciliary assembly.

PKHD1 PKHD1L1

4.41e-05751224586199
Pubmed

Glutamylation of the DNA sensor cGAS regulates its binding and synthase activity in antiviral immunity.

AGBL1 AGTPBP1

7.54e-05951226829768
Pubmed

IL-7Rα glutamylation and activation of transcription factor Sall3 promote group 3 ILC development.

AGBL1 AGTPBP1

1.38e-041251228794449
Pubmed

Genome cross-referencing and XREFdb: implications for the identification and analysis of genes mutated in human disease.

GK SLC26A2

3.18e-04185129090377
Pubmed

ASPP2 binds Par-3 and controls the polarity and proliferation of neural progenitors during CNS development.

RLBP1 TP53BP2

3.55e-041951220619750
Pubmed

Comparative analysis of 1196 orthologous mouse and human full-length mRNA and protein sequences.

GK SLC26A2

6.19e-04255128889551
Pubmed

Tubby family proteins are adapters for ciliary trafficking of integral membrane proteins.

KISS1R PKHD1

6.19e-042551228154160
Pubmed

Klf4 glutamylation is required for cell reprogramming and early embryonic development in mice.

AGBL1 AGTPBP1

6.19e-042551229593216
Pubmed

The LIFEdb database in 2006.

PDE5A KBTBD12 ATG9A IDH3G SERPINA6 PHLPP2

6.29e-0472051616381901
Pubmed

From ORFeome to biology: a functional genomics pipeline.

PDE5A KBTBD12 ATG9A IDH3G SERPINA6 PHLPP2

6.38e-0472251615489336
Pubmed

DNA cloning using in vitro site-specific recombination.

PDE5A KBTBD12 ATG9A IDH3G SERPINA6 PHLPP2

1.04e-0379451611076863
Pubmed

Genome-wide contribution of genotype by environment interaction to variation of diabetes-related traits.

NFAT5 AGBL1

1.08e-033351224204828
Pubmed

Early embryonic expression of murine coagulation system components.

SERPINB2 PROS1

1.15e-033451211154109
Pubmed

The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3.

RLBP1 RPS15 IDH3G ATP1B2 HBD

1.27e-0355251536293380
Cytoband4q27

TRPC3 PDE5A

2.76e-04225124q27
CoexpressionGSE13547_WT_VS_ZFX_KO_BCELL_ANTI_IGM_STIM_12H_DN

BTBD6 KISS1R TANC1 EZH1 TASL

1.31e-05159505M2983
CoexpressionBOCHKIS_FOXA2_TARGETS

GK KBTBD12 CCR8 SLC13A2 SERPINA6 TP53BP2 PROS1

1.76e-05434507M1806
CoexpressionBOCHKIS_FOXA2_TARGETS

GK KBTBD12 CCR8 SLC13A2 SERPINA6 TP53BP2 PROS1

2.81e-05467507MM1233
ToppCellCOPD-Stromal-Pericyte|COPD / Disease state, Lineage and Cell class

COL5A2 PXDN TANC1 ATP1B2 ADGRD1

2.41e-06184525a56264a22dfc2d3672b20134ab7c3c7c23da5ae1
ToppCell10x5'v1-week_14-16-Hematopoietic-MK-early_MK|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

STXBP5 PDE5A KBTBD12 HBD PROS1

3.20e-061955259b4f217325afb2efb9c65f298ac87649cb1e1af9
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COL5A2 PXDN TRPC3 PDE5A ADGRD1

3.28e-0619652512d9028f90c057c6e5cff00301793fa550e86c5a
ToppCellBronchial-10x5prime-Stromal-Pericyte-Muscle_pericyte_pulmonary|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

COL5A2 TRPC3 PDE5A ATP1B2 ADGRD1

3.62e-0620052512326cc6f0af24bacba9493dc79e7c7347db2f41
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte-Pericyte_2|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

COL5A2 TRPC3 PDE5A ATP1B2 ADGRD1

3.62e-06200525d2fcd3bd7c3223875f027eeb48ff621192a5f242
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Pericyte|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

COL5A2 TRPC3 PDE5A ATP1B2 ADGRD1

3.62e-062005254e1e19214aeebbdca004de7faaf4cc9d18498591
ToppCellControl_saline-Mesenchymal_myocytic|Control_saline / Treatment groups by lineage, cell group, cell type

ANO4 COL5A2 PDE5A ATP1B2 ADGRD1

3.62e-062005255ed4261157cd51109b314818133ac3a0d34ee5fa
ToppCellLPS_anti-TNF-Mesenchymal_myocytic|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ANO4 COL5A2 TRPC3 PDE5A ADGRD1

3.62e-0620052567dcbd86fbc79fd585d0793f979e4aac100326c9
ToppCellBronchial-10x5prime-Stromal-Pericyte|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

COL5A2 TRPC3 PDE5A ATP1B2 ADGRD1

3.62e-06200525362706445edb33b313684efe50b1f44f5f816e67
ToppCellControl_saline-Mesenchymal_myocytic-Pericyte|Control_saline / Treatment groups by lineage, cell group, cell type

COL5A2 TRPC3 PDE5A ATP1B2 ADGRD1

3.62e-06200525cb7ef774b6d300f8019c5b16a04e3ebd165e4f1c
ToppCellParenchymal-10x5prime-Stromal-Pericyte-Muscle_pericyte_pulmonary|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

COL5A2 TRPC3 PDE5A ATP1B2 ADGRD1

3.62e-06200525f9bc22ff17bb1c751e6b05bca3f403836f33459a
ToppCellParenchymal-10x5prime-Stromal-Pericyte|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

COL5A2 TRPC3 PDE5A ATP1B2 ADGRD1

3.62e-062005250a7640db28c708003d5da2d19eb651f6fedfd710
ToppCellLPS_IL1RA-Mesenchymal_myocytic|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ANO4 COL5A2 TRPC3 PDE5A ATP1B2

3.62e-0620052577631c471cc5d453a749784f838cfa6408caf09b
ToppCellfacs-Pancreas-Exocrine-24m-Epithelial-pancreatic_D_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GK SLC26A2 KBTBD12 AGBL1

3.39e-05157524370f44047ef438b8f1124c2c2761c150c0d8c57f
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL5A2 CNTNAP2 PKHD1 PKHD1L1

3.65e-05160524c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL5A2 CNTNAP2 PKHD1 PKHD1L1

3.65e-0516052425c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Neural-neural_cell-Schwann_Cell_/_Neural|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PCSK2 COL5A2 CNTNAP2 ATP1B2

3.74e-051615247d1bc73f4c82465b3f489d6737048b0cd54f22cf
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Neural-neural_cell-Schwann_Cell_/_Neural-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PCSK2 COL5A2 CNTNAP2 ATP1B2

3.74e-05161524410eef62c83c704cbfc5a1b643c4db11bbdcd81f
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Neural|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PCSK2 COL5A2 CNTNAP2 ATP1B2

3.74e-0516152471022485da6754a2b57b4c3e758e3de4c95cc292
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Neural-neural_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PCSK2 COL5A2 CNTNAP2 ATP1B2

3.74e-0516152459ae8a7c9a04ecaa335b8064852a5a91a21780bd
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-enterocyte_of_epithelium_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC26A2 SLC13A2 PLS1 PHLPP2

3.83e-05162524bc63a96ad3ba0b3433e3679d7a005f47709ff384
ToppCellfacs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-1|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NEXMIF CD109 SLC13A2 ADGRD1

3.83e-0516252456f1789e69a6cb29956e46aba92b290847327c1f
ToppCellAdult-Mesenchymal-pericyte_cell-D231|Adult / Lineage, Cell type, age group and donor

COL5A2 TRPC3 PDE5A ADGRD1

4.84e-05172524858cee96c1c06160863b4adcd7023c0d678bd50f
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL5A2 DCTN6 PKHD1L1 ADGRD1

4.95e-0517352430d67738633493d47f06ae452424382f069b6c0a
ToppCell5'-GW_trimst-1.5-LargeIntestine-Epithelial-goblet|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC13A2 SERPINA6 MUC5AC PLS1

5.06e-05174524e7cca4b6a3935fad61cf2a3d9984ab1ffa1a9447
ToppCell5'-GW_trimst-1.5-LargeIntestine-Epithelial-goblet-Goblet_cell|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC13A2 SERPINA6 MUC5AC PLS1

5.06e-05174524ad5b56f0ace6455c033834b931ec870cc0dc9290
ToppCellfacs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ZFYVE26 ATP1B2 PLS1 PRODH

5.18e-05175524bb898796662b97f7459b7dda7cecf6a9bde8b055
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL5A2 TRPC3 PDE5A ADGRD1

5.65e-05179524dc6cd46fa652b296ddbc41855f6377946d0a4cdc
ToppCelldroplet-Lung-nan-18m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPC3 PDE5A TANC1 ATP1B2

5.77e-05180524f6a05b3751b01e74b2de8440801b0eb2e723c199
ToppCelldroplet-Lung-nan-18m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPC3 PDE5A TANC1 ATP1B2

5.77e-05180524dfc75ae4395ff46fbec2c54915d98ead5a1ba1a1
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL5A2 TRPC3 PDE5A ADGRD1

6.16e-051835248a799807fbf24456a9811e0c64068187940a2f71
ToppCell10x5'v1-week_12-13-Hematopoietic-MK-MK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

PDE5A HBD PKHD1L1 PROS1

6.16e-051835246cbc88c27dc957d182526e84824f70c8e860bf74
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL5A2 TRPC3 PDE5A ADGRD1

6.29e-05184524689a8af81a79a4bb3123cfa01958c953eab5de98
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANO4 PDE5A AGBL1 ADGRD1

6.56e-051865246add08d4ca019ff2864acdd5ec2c66a59a574591
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL5A2 TRPC3 PDE5A ADGRD1

6.56e-05186524888e85a025bd982d36c910db0f5a3385b1ca3b28
ToppCellCOPD-Stromal-Pericyte|World / Disease state, Lineage and Cell class

TRPC3 TANC1 ATP1B2 ADGRD1

6.56e-051865248adfd2d1fda4e8aecc95192ea627bf7ed5214b8d
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ANO4 COL5A2 TRPC3 PDE5A

6.69e-05187524a9316e2818217ec5feae9cf8816f7249803caee6
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANO4 PDE5A AGBL1 ADGRD1

6.83e-05188524293f2fa99f5f96aa7fd2b2a5cc94ff60eeaabe11
ToppCell10x5'v1-week_17-19-Hematopoietic|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

PDE5A HBD PKHD1L1 PROS1

6.83e-05188524c00ba0abd0c7bb2c8f9166a2ac6220aae4f4d857
ToppCellCOPD-Myeloid-cMonocyte|COPD / Disease state, Lineage and Cell class

GK SERPINB2 IL1RAP AGTPBP1

6.98e-05189524d29f3a0bd23e6eb46389e6eb7ef21851c7b57545
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANO4 TRPC3 PDE5A ADGRD1

6.98e-051895247ab1cfc1657277858339f7258a0c4ae9cb42fdf8
ToppCellIPF-Myeloid-cMonocyte|Myeloid / Disease state, Lineage and Cell class

GK SERPINB2 IL1RAP AGTPBP1

6.98e-05189524ad7bb3a7de8e48c145e4382f90d30bb2159c2b76
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANO4 CNTNAP2 TANC1 AGBL1

7.12e-0519052426843ec1d19ac85a50990705353b802745d33e4d
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

PCSK2 COL5A2 CNTNAP2 PDE5A

7.12e-051905247986586b7c82e91c71102cc8c4d7a689ae63ab4d
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-A|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

STXBP5 CD109 ATG9A EZH1

7.12e-0519052463018acb7ad80415e861643162abdc2e55968ee4
ToppCellIPF-Myeloid-cMonocyte|IPF / Disease state, Lineage and Cell class

GK SERPINB2 IL1RAP AGTPBP1

7.12e-05190524a099f51f2b7618b6712af38eedd5ee64d8663a4a
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

COL5A2 PXDN ADGRD1 PROS1

7.12e-051905240fea33f2dc1efa23aaa2da1c318482a52a313ff1
ToppCell10x3'2.3-week_17-19-Hematopoietic-MK|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

PDE5A HBD PKHD1L1 PROS1

7.12e-0519052464060e4b56ac9989e659c2d5d2a6b6edeba4d8d4
ToppCellfacs-Lung-3m-Mesenchymal-myofibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL5A2 CD109 PDE5A ATP1B2

7.27e-05191524fd8331c7abdd999f55ba43d307945c6abfccbf84
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANO4 TRPC3 PDE5A ATP1B2

7.27e-051915247853ac7dff649150e6ff27cd4c8cf7c1fc034ed4
ToppCell10x5'v1-week_14-16-Hematopoietic-MK|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

PDE5A HBD PKHD1L1 PROS1

7.27e-051915247edc22e7e70697fb22690699efb352577162709b
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANO4 TRPC3 PDE5A ADGRD1

7.41e-05192524992d08092edbc68c47b945deb8708379738c239a
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature4_(1)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ANO4 COL5A2 SIK3 NFAT5

7.41e-051925246bba80887d6f64cf913a5c22f62baaddda417ce0
ToppCell3'-GW_trimst-1.5-LargeIntestine|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC26A2 CNTNAP2 PDE5A SLC13A2

7.41e-051925249946f5d5cab64936ca68d9f4dc9ce6eba85b43ab
ToppCell10x3'2.3-week_12-13-Hematopoietic-MK-MK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

PDE5A HBD PKHD1L1 PROS1

7.56e-051935243d4411b3c1cb160dec5db29f0c126d8827dfe185
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL5A2 TRPC3 PDE5A ADGRD1

7.72e-051945248f19e553f18c313c2a2ff9453884b9484b255d71
ToppCell10x5'v1-week_12-13-Hematopoietic-MK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

STXBP5 PDE5A HBD PROS1

7.72e-05194524245a3eb6db9c862b73ad34a8cd2898a3688c16f6
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL5A2 TRPC3 PDE5A ADGRD1

7.72e-0519452467fbb81b7d20cb63be27b2a2beea5b5689f8e08c
ToppCell390C-Myeloid-Dendritic-cDC2|390C / Donor, Lineage, Cell class and subclass (all cells)

GK CD109 NFAT5 TASL

7.72e-05194524705fa653c11b6c8a427e007533aa4a4bb5845078
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL5A2 TRPC3 PDE5A ADGRD1

7.72e-05194524f95935153bd2c4c3c7b2b729da6f7e98b45fed79
ToppCellCOVID-19-lung-Pericytes/_Smooth_Muscle|lung / Disease (COVID-19 only), tissue and cell type

COL5A2 TRPC3 PDE5A ADGRD1

7.72e-051945245e1e0513a54ec4cf0b247ec85c9fbc68dfac1da3
ToppCellfacs-Lung-3m-Mesenchymal-myofibroblast-myofibroblast_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL5A2 CD109 PDE5A ATP1B2

7.87e-05195524c6bb16c0076639c6ddef1a15d8cba44bc29c077d
ToppCelldroplet-Lung-immune-endo-depleted-3m-Mesenchymal-Myofibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL5A2 CD109 PDE5A ATP1B2

7.87e-051955243f64e2313ec79a6d5f4013a52722d071172f6c5d
ToppCell5'-GW_trimst-1-SmallIntestine-Neuronal-Glial_immature|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RLBP1 PCSK2 COL5A2 IL1RAP

7.87e-051955249fea1ddb68da83ca43dd8006c9e51295b1817f0e
ToppCellfacs-Lung-3m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL5A2 CD109 PDE5A ATP1B2

7.87e-05195524ea89f80d3d7e9f737442f7c1aa1791d277ffc90c
ToppCelldroplet-Lung-immune-endo-depleted-3m-Mesenchymal-pulmonary_interstitial_fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL5A2 CD109 PDE5A ATP1B2

7.87e-051955247a5108335353ac160b684650c5da97d6f7f4dbcf
ToppCell5'-GW_trimst-1-SmallIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RLBP1 PCSK2 COL5A2 IL1RAP

8.03e-051965249afd0a7135028a446f06bb68f334e79b8f171b45
ToppCellCOVID-19-lung-Pericytes/_Smooth_Muscle|COVID-19 / Disease (COVID-19 only), tissue and cell type

COL5A2 TRPC3 PDE5A ADGRD1

8.03e-05196524754a3613340932563cd8424d775e18b93c3a1aaa
ToppCellTransverse-T_cell-Treg|T_cell / Region, Cell class and subclass

GK PKHD1 CCR8 TASL

8.19e-05197524b7a1637e4baadd657f6279f4aa96cd590c9cd8c9
ToppCellFibroblast|World / shred by cell class for bronchial biopsy

PDE5A ATP1B2 ADGRD1 PROS1

8.19e-051975248bf9846228b6b6721b10375fe54a2fb389ff64a6
ToppCellBronchus_Control_(B.)|World / Sample group, Lineage and Cell type

SLC26A2 SERPINB2 SIK3 MUC5AC

8.19e-05197524b6dff2ee108813e18657e2d8cf850e2423f8c8e9
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL5A2 PXDN PDE5A PROS1

8.19e-0519752443b5f8e917506c1717f9311584901b506ffd2c79
ToppCellFetal_29-31_weeks|World / Lineage, Cell type, age group and donor

COL5A2 PXDN CNTNAP2 RPS15

8.51e-051995245b9d355795dd03a22f0961dfd143425c367a4654
ToppCellTransverse-T_cell-Treg|Transverse / Region, Cell class and subclass

GK RPS15 PKHD1 CCR8

8.51e-051995245a483208fbd205a6aac443c22179742806942934
ToppCellTransverse-(1)_T_cell-(15)_Treg|Transverse / shred on region, Cell_type, and subtype

GK RPS15 PKHD1 CCR8

8.51e-05199524807a6dd05c4112ce7c62ed9f37bb02b783c60bc7
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

COL5A2 TRPC3 PDE5A ATP1B2

8.68e-05200524b5b5a32925f225610fe25a021a742d6397162863
ToppCellParenchyma_Control_(B.)-Stromal-TX-Smooth_muscle-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

TRPC3 PDE5A TANC1 ADGRD1

8.68e-052005240c648941447c738caf62f2d71e296d6cca492c8b
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ANO4 TRPC3 PDE5A ADGRD1

8.68e-05200524f599e4b051ac3dad11ad437e98dc8ea6754cca53
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Pericyte|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

COL5A2 TRPC3 PDE5A ATP1B2

8.68e-05200524b22cae282591d8dead9869c2adbb9632615f50f7
ToppCellNeuronal-Inhibitory-iA-iA_3(VIP)-VIP_3-CHRM2|Neuronal / cells hierarchy compared to all cells using T-Statistic

ANO4 PXDN CNTNAP2 ATP1B2

8.68e-05200524501a3b93624df463458a35d3e6648d4ccc941724
ToppCellParenchyma_COVID-19-Stromal-TX-Smooth_muscle-1|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

COL5A2 PXDN PDE5A ATP1B2

8.68e-0520052478e9a40153d7ba5d9ea6393a37d26fc5c0220867
ToppCellNeuronal-Inhibitory-iA-iA_3(VIP)-VIP_3-CHRM2-L1-3|Neuronal / cells hierarchy compared to all cells using T-Statistic

ANO4 PXDN CNTNAP2 ATP1B2

8.68e-05200524d1f36a8232411933b1494168ec912fd0e5246428
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TRPC3 PDE5A TANC1 ADGRD1

8.68e-05200524522a51a284d2992d519c4669e1a48c8ebcc08c80
ToppCellLung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Smooth_muscle-1|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

COL5A2 PXDN PDE5A ATP1B2

8.68e-05200524c46e06b4f22d3456e67bc62a9ac198e8041965ad
ToppCellLung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Smooth_muscle-1-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

COL5A2 PXDN PDE5A ATP1B2

8.68e-0520052443b76e382b38b9856c07557a75e5b1ce0cee1d9e
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Pericyte-Pericyte_2|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

COL5A2 TRPC3 PDE5A ADGRD1

8.68e-05200524786f1ae53e60b5ffbf4bfd393d10b802478148b3
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

TRPC3 PDE5A TANC1 ADGRD1

8.68e-0520052494f1fa61aa82eb9f411b2b1cb759476939ab5db7
ToppCellControl_saline-Mesenchymal_myocytic-Pericyte-Pericyte_2|Control_saline / Treatment groups by lineage, cell group, cell type

COL5A2 TRPC3 PDE5A ADGRD1

8.68e-05200524bc8949eb34482aca166c4602ff6ab876cb4c2c3c
ToppCelldroplet-Lung-30m-Hematologic-myeloid-interstitial_macrophage-interstitial_macrophage_l14|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

BTBD6 SERPINB2 IL1RAP

2.58e-04106523ede8407ad253080d1fa2a6e2aacf549ce220309a
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_dendritic-CD141-positive_myeloid_dendritic_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

GK CD109 ADGRD1

5.13e-041345230b1bb6fee8a2d8c27bca6d9cac6b47e85073dbf7
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_PT|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ANO4 TANC1 PLS1

5.13e-04134523cb676d5bbc468bd3ce1b6712d41c986ee9221ac5
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_2|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

SLC26A2 CD109 SERPINB2

5.24e-041355234451c44f3ad788437f4e2ae81049fbbab53f967e
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

SLC26A2 CD109 SERPINB2

5.24e-0413552345f67f33c8320d9fb6dbceae603b564f6a8ffd1e
ToppCellLPS-antiTNF-Myeloid-Myeloid_granulocytic|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GK IL1RAP AGTPBP1

6.20e-041435234a0f26eef935fe68a1da5d319503059a8a8682dd
ToppCellLPS-antiTNF-Myeloid-Myeloid_granulocytic-Neutrophils|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GK IL1RAP AGTPBP1

6.20e-0414352365328a0a2f3972fac596e07933e74b2ef7cceb84
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ANO4 COL5A2 PDE5A

6.33e-041445231c001a5a3bbe4ecbce8305f8b260e933033550dd
ToppCell343B-Myeloid-Macrophage-SPP1+_Macrophage_3|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

STXBP5 CNTNAP2 ATP1B2

6.33e-041445235e948d4cb913ccd8f82262a1b4d20967aadab3ab
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Crispld2_Htr2c|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ANO4 CNTNAP2 PDE5A

6.58e-0414652347368f981180ca6a8c81a50f7f9430f12456f609
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ANO4 PCSK2 ATG9A

6.85e-04148523f85dc34f6a4a15ecffa4fbd5644dea12ce30089b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ANO4 PCSK2 ATG9A

6.85e-041485234b1fdf90c585f89cee1cf521db4e3fafc9d74d9a
Diseasehemoglobin measurement, hemoglobin A2 measurement

HBD HBD

2.80e-055502EFO_0004509, EFO_0005845
Diseasehemoglobin E disease

HBD HBD

4.20e-056502MONDO_0016243
Diseaselevel of Phosphatidylethanolamine (18:1_18:1) in blood serum

CNTNAP2 SIK3

2.53e-0414502OBA_2045142
DiseaseMalignant neoplasm of breast

MAN2C1 CD109 SERPINB2 RECQL ZFYVE26 SIK3 TP53BP2 PRODH

4.14e-041074508C0006142
DiseaseColorectal Carcinoma

PCSK2 ERGIC3 CD109 PKHD1 AGTPBP1 PROS1

1.16e-03702506C0009402

Protein segments in the cluster

PeptideGeneStartEntry
GVLAVNGCAVVFQYM

ADGRD1

776

Q6QNK2
GMTEVQCGKVAFQFQ

BTBD6

501

Q96KE9
QGEAGQKCMVGYVNA

ANO4

811

Q32M45
IINCEKSNSQFNYGM

AGTPBP1

766

Q9UPW5
TQCSQFLYGVQEKMG

TP53BP2

1041

Q13625
INCEKPNSQFNYGMQ

AGBL1

651

Q96MI9
KQYVNEAFQAGAMTC

NFXL1

146

Q6ZNB6
GQMCFQIGQAKNTYG

GK3P

266

Q14409
CYKIQNFNNVIPEGM

IL1RAP

181

Q9NPH3
INFYAGANQSMNVTC

ATP1B2

186

P14415
LGGNMKKIENCNYAV

PLS1

451

Q14651
VIFCGLGIQNTQMYE

PDE5A

496

O76074
MQEQKNEGCQVYGFL

ERGIC3

191

Q9Y282
GDFMCKFVNYIQQVS

KISS1R

111

Q969F8
QDQQGPFKMCLNYEV

MUC5AC

3301

P98088
QDQQGPFKMCLNYEV

MUC5AC

4706

P98088
CGNFKVNAIYGLMVA

OR52N2

191

Q8NGI0
QQTSGMFLFGIQNNC

NFAT5

1441

O94916
CGEQNMINFAPNIYI

CD109

921

Q6YHK3
VMPNLYGNIVNNVCA

IDH3G

271

P51553
QKSCSQIFNYLGRQM

CCR8

316

P51685
YNLHQKNGFTCMLIG

ATG9A

51

Q7Z3C6
VGQMCFQIGQAKNTY

GK

271

P32189
GEEIACTQNGQMYLN

COL5A2

36

P05997
LQGQNFFLQEFGKMC

MAN2C1

351

Q9NTJ4
KNFKGCMESINYNGV

CNTNAP2

331

Q9UHC6
QMQAAYQKVVAGVAN

HBD

126

P02042
GQVVMLYINCKVNGH

DDI2

231

Q5TDH0
TNNVFEVGCYSQAMK

DCTN6

86

O00399
GEKMQEQQQAAYCVI

SLC13A2

301

Q13183
QLVQMNYVGNGTVFF

SERPINA6

251

P08185
GGQMKIKNQYLITNC

KBTBD12

391

Q3ZCT8
FTSCGFMQQIQKGSY

SERPINB2

76

P05120
QINSVFNKYCVNMQG

UTP25

541

Q68CQ4
FNKYCVNMQGQVAVR

UTP25

546

Q68CQ4
DIGIQCINAGENMKY

NEXMIF

181

Q5QGS0
QVYFGQLLGMCDQIS

PRODH

521

O43272
LQQECEQLQKMYGGQ

SIK3

651

Q9Y2K2
SLMQVGGYNNQAKTC

TANC1

1771

Q9C0D5
YQFLMQGFICKQTDQ

PKHD1

3396

P08F94
FGNCNGIAMVDYLQK

STXBP5

646

Q5T5C0
PVNAFYNGCMEVNIN

PROS1

631

P07225
YNGCMEVNINGVQLD

PROS1

636

P07225
GQQKLYEMVSYCQNI

RECQL

436

P46063
GSMVGVYNGKTFNQV

RPS15

91

P62841
GCQDNVGAMVVYLNI

PHLPP2

1021

Q6ZVD8
TVKANQEMYAIGFCN

SLC26A2

411

P50443
CKNYNDLQIAGGQVM

TASL

121

Q9HAI6
SVNPNCYAKVVMVNG

EZH1

691

Q92800
DQGIYQCMAKNVAGE

PXDN

311

Q92626
NGFCIIENFKGFTMQ

RLBP1

196

P12271
KGYNFGNELTQNMAV

PKHD1L1

1261

Q86WI1
QNMAVYVGGKTCQIL

PKHD1L1

1271

Q86WI1
QCQNLTLYQGFCAMK

ZFYVE26

491

Q68DK2
KTLNVNCVDYMGQNA

TRPC3

51

Q13507
NNNICGVGVAYNSKV

PCSK2

221

P16519