Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhistone H3 methyltransferase activity

KMT2C SUV39H1 EZH2 SMYD3

6.44e-0644554GO:0140938
GeneOntologyMolecularFunctionreceptor ligand activity

VEGFC TGFB2 TGFB3 ASIP AGRP WNT9A GRN FLRT3 FLRT2

1.68e-05547559GO:0048018
GeneOntologyMolecularFunctionsignaling receptor activator activity

VEGFC TGFB2 TGFB3 ASIP AGRP WNT9A GRN FLRT3 FLRT2

1.86e-05554559GO:0030546
GeneOntologyMolecularFunctionprotein-lysine N-methyltransferase activity

KMT2C SUV39H1 EZH2 SMYD3

3.68e-0568554GO:0016279
GeneOntologyMolecularFunctionlysine N-methyltransferase activity

KMT2C SUV39H1 EZH2 SMYD3

3.90e-0569554GO:0016278
GeneOntologyMolecularFunctionsignaling receptor regulator activity

VEGFC TGFB2 TGFB3 ASIP AGRP WNT9A GRN FLRT3 FLRT2

4.27e-05616559GO:0030545
GeneOntologyMolecularFunctionhistone methyltransferase activity

KMT2C SUV39H1 EZH2 SMYD3

4.36e-0571554GO:0042054
GeneOntologyMolecularFunctiontype III transforming growth factor beta receptor binding

TGFB2 TGFB3

4.45e-054552GO:0034714
GeneOntologyMolecularFunctionryanodine-sensitive calcium-release channel activity

RYR1 RYR2

4.45e-054552GO:0005219
GeneOntologyMolecularFunctionfibroblast growth factor receptor binding

FLRT3 FLRT2 FLRT1

6.87e-0529553GO:0005104
GeneOntologyMolecularFunctionmelanocortin receptor binding

ASIP AGRP

7.41e-055552GO:0031779
GeneOntologyMolecularFunctionS-adenosylmethionine-dependent methyltransferase activity

KMT2C SUV39H1 EZH2 SMYD3 DNMT3L

1.10e-04172555GO:0008757
GeneOntologyMolecularFunctioncalcium-induced calcium release activity

RYR1 RYR2

1.11e-046552GO:0048763
GeneOntologyMolecularFunctionubiquitin conjugating enzyme binding

RNF125 ARIH2 RNF217

1.32e-0436553GO:0031624
GeneOntologyMolecularFunctionzinc ion binding

POLR3K RNF125 SEC24C TRIM42 CTCF SUV39H1 ARIH2 ZIM2 ADAMTS20 RNF217

1.40e-048915510GO:0008270
GeneOntologyMolecularFunctionchromatin insulator sequence binding

CTCFL CTCF

1.55e-047552GO:0043035
GeneOntologyMolecularFunctionneuropeptide receptor binding

ASIP AGRP CCKBR

1.68e-0439553GO:0071855
GeneOntologyMolecularFunctionprotein methyltransferase activity

KMT2C SUV39H1 EZH2 SMYD3

1.86e-04103554GO:0008276
GeneOntologyMolecularFunctionN-methyltransferase activity

KMT2C SUV39H1 EZH2 SMYD3

2.00e-04105554GO:0008170
GeneOntologyMolecularFunctionchromatin loop anchoring activity

CTCF MSL2

2.06e-048552GO:0140587
GeneOntologyMolecularFunctionubiquitin-like protein conjugating enzyme binding

RNF125 ARIH2 RNF217

2.10e-0442553GO:0044390
GeneOntologyMolecularFunctionDNA-DNA tethering activity

CTCF MSL2

2.65e-049552GO:0106260
GeneOntologyMolecularFunctionmethyltransferase activity

KMT2C SUV39H1 EZH2 SMYD3 DNMT3L

2.97e-04213555GO:0008168
GeneOntologyMolecularFunctionhistone H3K4 trimethyltransferase activity

KMT2C SMYD3

3.31e-0410552GO:0140999
GeneOntologyMolecularFunctiontransition metal ion binding

POLR3K RNF125 SEC24C TRIM42 CTCF SUV39H1 ARIH2 OGFOD2 ZIM2 ADAMTS20 RNF217

3.38e-0411895511GO:0046914
GeneOntologyMolecularFunctiontransferase activity, transferring one-carbon groups

KMT2C SUV39H1 EZH2 SMYD3 DNMT3L

3.74e-04224555GO:0016741
GeneOntologyMolecularFunctionhistone modifying activity

KMT2C SUV39H1 EZH2 SMYD3 MSL2

4.14e-04229555GO:0140993
GeneOntologyMolecularFunctiontype II transforming growth factor beta receptor binding

TGFB2 TGFB3

4.83e-0412552GO:0005114
GeneOntologyMolecularFunctionmolecular adaptor activity

KMT2C LIMD1 LMO1 CTCF LMO3 FLRT3 FLRT2 FLRT1 EZH2 SPPL2C MSL2

1.02e-0313565511GO:0060090
GeneOntologyMolecularFunctionintracellularly gated calcium channel activity

RYR1 RYR2

1.11e-0318552GO:0015278
GeneOntologyMolecularFunctionchromatin DNA binding

CTCFL CTCF EZH2 MSL2

1.15e-03167554GO:0031490
GeneOntologyMolecularFunctiongrowth factor receptor binding

VEGFC FLRT3 FLRT2 FLRT1

1.32e-03173554GO:0070851
GeneOntologyMolecularFunctiongrowth factor activity

VEGFC TGFB2 TGFB3 GRN

1.32e-03173554GO:0008083
GeneOntologyMolecularFunctionhistone H3K4 methyltransferase activity

KMT2C SMYD3

1.37e-0320552GO:0042800
GeneOntologyMolecularFunctionmolecular function activator activity

VEGFC TGFB2 TGFB3 ASIP AGRP WNT9A GRN FLRT3 FLRT2 DNMT3L

1.78e-0312335510GO:0140677
GeneOntologyMolecularFunctionchemorepellent activity

FLRT3 FLRT2

2.88e-0329552GO:0045499
GeneOntologyMolecularFunctiontransforming growth factor beta receptor binding

TGFB2 TGFB3

3.29e-0331552GO:0005160
GeneOntologyMolecularFunctionligand-gated calcium channel activity

RYR1 RYR2

3.29e-0331552GO:0099604
GeneOntologyMolecularFunctionintracellularly ligand-gated monoatomic ion channel activity

RYR1 RYR2

3.72e-0333552GO:0005217
GeneOntologyMolecularFunctionneuropeptide hormone activity

ASIP AGRP

3.95e-0334552GO:0005184
GeneOntologyMolecularFunctionneuropeptide activity

ASIP AGRP

3.95e-0334552GO:0160041
GeneOntologyMolecularFunctioncytokine activity

TGFB2 TGFB3 WNT9A GRN

4.96e-03250554GO:0005125
GeneOntologyMolecularFunctionamide binding

TGFB2 ITGB2 RYR2 CCKBR

9.23e-03299554GO:0033218
GeneOntologyBiologicalProcessepigenetic programming of gene expression

CTCFL CTCF ASIP SUV39H1 DNMT3L

1.33e-0749515GO:0043045
GeneOntologyBiologicalProcessuterine wall breakdown

TGFB2 TGFB3

5.99e-062512GO:0042704
GeneOntologyBiologicalProcessepigenetic programming in the zygotic pronuclei

ASIP SUV39H1 DNMT3L

9.45e-0617513GO:0044725
GeneOntologyBiologicalProcessfacultative heterochromatin formation

CTCF SUV39H1 EZH2 DNMT3L

1.03e-0555514GO:0140718
GeneOntologyBiologicalProcessepigenetic regulation of gene expression

CTCFL CTCF ASIP SUV39H1 EZH2 DNMT3L MSL2

1.59e-05330517GO:0040029
GeneOntologyBiologicalProcessresponse to hypoxia

VEGFC TGFB2 TGFB3 LIMD1 SUV39H1 RYR1 RYR2

2.24e-05348517GO:0001666
GeneOntologyBiologicalProcessresponse to decreased oxygen levels

VEGFC TGFB2 TGFB3 LIMD1 SUV39H1 RYR1 RYR2

2.99e-05364517GO:0036293
GeneOntologyBiologicalProcesschromatin remodeling

KMT2C CTCFL CTCF ASIP SUV39H1 EZH2 SMYD3 DNMT3L MSL2

7.46e-05741519GO:0006338
GeneOntologyBiologicalProcessresponse to oxygen levels

VEGFC TGFB2 TGFB3 LIMD1 SUV39H1 RYR1 RYR2

8.55e-05430517GO:0070482
GeneOntologyBiologicalProcessgenomic imprinting

CTCFL CTCF DNMT3L

8.81e-0535513GO:0071514
GeneOntologyBiologicalProcessregulation of epithelial to mesenchymal transition involved in endocardial cushion formation

TGFB2 TGFB3

8.93e-056512GO:1905005
GeneOntologyBiologicalProcessfibroblast growth factor receptor signaling pathway

FLRT3 FLRT2 FLRT1 ITGB1

1.01e-0498514GO:0008543
GeneOntologyBiologicalProcessrelease of sequestered calcium ion into cytosol by sarcoplasmic reticulum

HRC RYR1 RYR2

1.04e-0437513GO:0014808
GeneOntologyBiologicalProcessrelease of sequestered calcium ion into cytosol by endoplasmic reticulum

HRC RYR1 RYR2

1.22e-0439513GO:1903514
GeneOntologyBiologicalProcessembryo development

VEGFC TGFB2 TGFB3 SEC24C CTCF SUV39H1 WNT9A GRN FLRT3 PLXNB2 ITGB1 RYR2

1.55e-0414375112GO:0009790
GeneOntologyBiologicalProcessDNA methylation-dependent constitutive heterochromatin formation

CTCF EZH2 DNMT3L

1.76e-0444513GO:0006346
GeneOntologyBiologicalProcesssarcoplasmic reticulum calcium ion transport

HRC RYR1 RYR2

1.76e-0444513GO:0070296
GeneOntologyBiologicalProcesscell adhesion involved in heart morphogenesis

TGFB2 FLRT2

2.13e-049512GO:0061343
GeneOntologyBiologicalProcesspositive regulation of heart contraction

TGFB2 HRC RYR2

2.42e-0449513GO:0045823
GeneOntologyBiologicalProcesscellular response to fibroblast growth factor stimulus

FLRT3 FLRT2 FLRT1 ITGB1

2.50e-04124514GO:0044344
GeneOntologyBiologicalProcessrhythmic process

TGFB2 TGFB3 AGRP SUV39H1 EZH2 CCKBR

2.52e-04360516GO:0048511
GeneOntologyBiologicalProcessnegative regulation of keratinocyte differentiation

TGFB2 EZH2

2.66e-0410512GO:0045617
GeneOntologyBiologicalProcessmethylation

KMT2C SUV39H1 EZH2 SMYD3 DNMT3L

2.76e-04234515GO:0032259
GeneOntologyBiologicalProcesspositive regulation of blood circulation

TGFB2 HRC RYR2

3.06e-0453513GO:1903524
GeneOntologyBiologicalProcesschromatin organization

KMT2C CTCFL CTCF ASIP SUV39H1 EZH2 SMYD3 DNMT3L MSL2

3.11e-04896519GO:0006325
GeneOntologyBiologicalProcessresponse to fibroblast growth factor

FLRT3 FLRT2 FLRT1 ITGB1

3.17e-04132514GO:0071774
GeneOntologyBiologicalProcessadult feeding behavior

ASIP AGRP

3.25e-0411512GO:0008343
GeneOntologyBiologicalProcesscellular response to caffeine

RYR1 RYR2

3.25e-0411512GO:0071313
GeneOntologyBiologicalProcessembryonic neurocranium morphogenesis

TGFB2 TGFB3

3.25e-0411512GO:0048702
GeneOntologyBiologicalProcesschordate embryonic development

TGFB2 TGFB3 SEC24C CTCF SUV39H1 WNT9A GRN PLXNB2 ITGB1

3.38e-04906519GO:0043009
GeneOntologyBiologicalProcessdevelopmental growth

TGFB2 KMT2C SUV39H1 ARIH2 GRN FLRT3 FLRT1 EZH2 ITGB1

3.52e-04911519GO:0048589
GeneOntologyBiologicalProcessembryo development ending in birth or egg hatching

TGFB2 TGFB3 SEC24C CTCF SUV39H1 WNT9A GRN PLXNB2 ITGB1

4.06e-04929519GO:0009792
GeneOntologyBiologicalProcessrelease of sequestered calcium ion into cytosol

TGFB2 HRC RYR1 RYR2

4.65e-04146514GO:0051209
GeneOntologyBiologicalProcessnegative regulation of sequestering of calcium ion

TGFB2 HRC RYR1 RYR2

4.77e-04147514GO:0051283
GeneOntologyBiologicalProcessheart development

TGFB2 TGFB3 CTCF FLRT3 FLRT2 ITGB1 RYR1 RYR2

4.99e-04757518GO:0007507
GeneOntologyBiologicalProcessregulation of sequestering of calcium ion

TGFB2 HRC RYR1 RYR2

5.02e-04149514GO:0051282
GeneOntologyBiologicalProcesspositive regulation of epithelial to mesenchymal transition

TGFB2 TGFB3 EZH2

5.09e-0463513GO:0010718
GeneOntologyBiologicalProcessregulation of cardiac epithelial to mesenchymal transition

TGFB2 TGFB3

5.35e-0414512GO:0062042
GeneOntologyBiologicalProcessnegative regulation of macrophage cytokine production

TGFB2 TGFB3

5.35e-0414512GO:0010936
GeneOntologyBiologicalProcesscellular response to purine-containing compound

RYR1 RYR2

5.35e-0414512GO:0071415
GeneOntologyBiologicalProcesssequestering of calcium ion

TGFB2 HRC RYR1 RYR2

5.55e-04153514GO:0051208
GeneOntologyBiologicalProcesspositive regulation of nervous system development

VEGFC FLRT3 FLRT2 FLRT1 PLXNB2 ITGB1

5.57e-04418516GO:0051962
GeneOntologyBiologicalProcessmulticellular organismal reproductive process

TGFB2 TGFB3 CTCFL CTCF AGRP GRN ITGB1 SPPL2C CCKBR DNMT3L

5.90e-0411945110GO:0048609
GeneOntologyBiologicalProcessregulation of cell shape

LIMD1 FGD2 PLXNB2 ITGB2

6.41e-04159514GO:0008360
GeneOntologyBiologicalProcesscirculatory system development

VEGFC TGFB2 TGFB3 CTCF GRN FLRT3 FLRT2 ITGB1 ITGB2 RYR1 RYR2

6.63e-0414425111GO:0072359
GeneOntologyBiologicalProcessprotein-DNA complex organization

KMT2C CTCFL CTCF ASIP SUV39H1 EZH2 SMYD3 DNMT3L MSL2

6.86e-04999519GO:0071824
GeneOntologyBiologicalProcessheterochromatin formation

CTCF SUV39H1 EZH2 DNMT3L

7.03e-04163514GO:0031507
GeneOntologyBiologicalProcessnegative regulation of epidermis development

TGFB2 EZH2

7.04e-0416512GO:0045683
GeneOntologyBiologicalProcessnegative regulation of epidermal cell differentiation

TGFB2 EZH2

7.04e-0416512GO:0045605
GeneOntologyBiologicalProcessregulation of nervous system development

VEGFC FLRT3 FLRT2 FLRT1 EZH2 PLXNB2 ITGB1

8.25e-04625517GO:0051960
GeneOntologyBiologicalProcesscardioblast differentiation

TGFB2 ITGB1

8.94e-0418512GO:0010002
GeneOntologyBiologicalProcessepithelial to mesenchymal transition involved in endocardial cushion formation

TGFB2 TGFB3

9.98e-0419512GO:0003198
GeneOntologyBiologicalProcesspositive regulation of sequestering of calcium ion

TGFB2 RYR2

9.98e-0419512GO:0051284
GeneOntologyBiologicalProcesscell-cell adhesion via plasma-membrane adhesion molecules

TGFB2 FLRT3 PLXNB2 ITGB1 ITGB2

1.03e-03313515GO:0098742
GeneOntologyBiologicalProcesscellular response to growth factor stimulus

VEGFC TGFB2 TGFB3 FLRT3 FLRT2 FLRT1 ITGB1 RYR1

1.06e-03850518GO:0071363
GeneOntologyBiologicalProcessheart morphogenesis

TGFB2 TGFB3 FLRT2 RYR1 RYR2

1.16e-03321515GO:0003007
GeneOntologyBiologicalProcessregulation of cytosolic calcium ion concentration

HRC RYR1 RYR2

1.18e-0384513GO:0051480
GeneOntologyBiologicalProcessresponse to caffeine

RYR1 RYR2

1.22e-0321512GO:0031000
GeneOntologyBiologicalProcesspositive regulation of synapse assembly

FLRT3 FLRT2 FLRT1

1.26e-0386513GO:0051965
GeneOntologyBiologicalProcessregulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion

HRC RYR2

1.34e-0322512GO:0010881
GeneOntologyBiologicalProcessresponse to growth factor

VEGFC TGFB2 TGFB3 FLRT3 FLRT2 FLRT1 ITGB1 RYR1

1.36e-03883518GO:0070848
GeneOntologyBiologicalProcesscell adhesion mediated by integrin

TGFB2 ITGB1 ITGB2

1.48e-0391513GO:0033627
GeneOntologyBiologicalProcessregulation of cell division

VEGFC TGFB2 TGFB3 ZFYVE26

1.53e-03201514GO:0051302
GeneOntologyBiologicalProcessnegative regulation of gene expression, epigenetic

CTCF SUV39H1 EZH2 DNMT3L

1.59e-03203514GO:0045814
GeneOntologyBiologicalProcessresponse to abiotic stimulus

VEGFC TGFB2 TGFB3 KMT2C LIMD1 AGRP SUV39H1 ITGB1 RYR1 RYR2

1.61e-0313615110GO:0009628
GeneOntologyBiologicalProcessmonoatomic cation homeostasis

TGFB2 HRC GRN SPPL2C RYR1 RYR2 CCKBR

1.66e-03705517GO:0055080
GeneOntologyBiologicalProcessregulation of protein phosphorylation

VEGFC TGFB2 FGD2 HRC EZH2 PLXNB2 ITGB1 ITGB2 SMYD3

1.66e-031133519GO:0001932
GeneOntologyBiologicalProcessovulation cycle

TGFB2 TGFB3 CCKBR

1.68e-0395513GO:0042698
GeneOntologyBiologicalProcesscardiac left ventricle morphogenesis

TGFB2 RYR2

1.73e-0325512GO:0003214
GeneOntologyBiologicalProcessnegative regulation of cytosolic calcium ion concentration

HRC RYR2

1.73e-0325512GO:0051481
GeneOntologyBiologicalProcesspositive regulation of cell differentiation

VEGFC TGFB2 TGFB3 WNT9A ADAMTS20 LMO3 EZH2 PLXNB2 ITGB1

1.75e-031141519GO:0045597
GeneOntologyBiologicalProcessembryonic morphogenesis

VEGFC TGFB2 TGFB3 WNT9A FLRT3 PLXNB2 RYR2

1.77e-03713517GO:0048598
GeneOntologyBiologicalProcessmonoatomic ion homeostasis

TGFB2 HRC GRN SPPL2C RYR1 RYR2 CCKBR

1.82e-03717517GO:0050801
GeneOntologyBiologicalProcessregulation of release of sequestered calcium ion into cytosol

TGFB2 HRC RYR2

1.84e-0398513GO:0051279
GeneOntologyBiologicalProcesscell communication by electrical coupling involved in cardiac conduction

HRC RYR2

1.88e-0326512GO:0086064
GeneOntologyBiologicalProcessintracellular calcium ion homeostasis

TGFB2 HRC SPPL2C RYR1 RYR2

1.89e-03359515GO:0006874
GeneOntologyBiologicalProcessneuroinflammatory response

GRN ITGB1 ITGB2

2.00e-03101513GO:0150076
GeneOntologyBiologicalProcesssensory organ development

TGFB2 TGFB3 KMT2C RP1L1 WNT9A GRN OTOG

2.02e-03730517GO:0007423
GeneOntologyBiologicalProcesssecondary palate development

TGFB2 TGFB3

2.02e-0327512GO:0062009
GeneOntologyBiologicalProcesscalcium ion transmembrane import into cytosol

TGFB2 HRC RYR1 RYR2

2.02e-03217514GO:0097553
GeneOntologyBiologicalProcesspositive regulation of angiogenesis

VEGFC GRN ITGB1 ITGB2

2.13e-03220514GO:0045766
GeneOntologyBiologicalProcessregulation of cardiac muscle contraction by calcium ion signaling

HRC RYR2

2.17e-0328512GO:0010882
GeneOntologyBiologicalProcesspositive regulation of cell division

VEGFC TGFB2 TGFB3

2.18e-03104513GO:0051781
GeneOntologyBiologicalProcessneuroblast proliferation

VEGFC PLXNB2 ITGB1

2.18e-03104513GO:0007405
GeneOntologyBiologicalProcesspositive regulation of vasculature development

VEGFC GRN ITGB1 ITGB2

2.23e-03223514GO:1904018
GeneOntologyBiologicalProcesstissue morphogenesis

VEGFC TGFB2 TGFB3 FLRT3 PLXNB2 ITGB1 RYR2

2.35e-03750517GO:0048729
GeneOntologyBiologicalProcesscell morphogenesis

TGFB2 LIMD1 FGD2 FLRT3 FLRT2 FLRT1 PLXNB2 ITGB1 ITGB2

2.38e-031194519GO:0000902
GeneOntologyBiologicalProcessembryonic skeletal system morphogenesis

TGFB2 TGFB3 WNT9A

2.49e-03109513GO:0048704
GeneOntologyBiologicalProcesscell junction organization

TGFB2 TGFB3 GRN FLRT3 FLRT2 FLRT1 PLXNB2 ITGB1

2.51e-03974518GO:0034330
GeneOntologyCellularComponentextracellular matrix

TGFB2 TGFB3 SBSPON ADAMTS20 COL6A5 MUC5B FLRT3 FLRT2 FLRT1 PLXNB2 ITGB1 OTOG

6.78e-086565312GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

TGFB2 TGFB3 SBSPON ADAMTS20 COL6A5 MUC5B FLRT3 FLRT2 FLRT1 PLXNB2 ITGB1 OTOG

7.01e-086585312GO:0030312
GeneOntologyCellularComponentsarcoplasmic reticulum membrane

HRC RYR1 RYR2

2.03e-0445533GO:0033017
GeneOntologyCellularComponentjunctional sarcoplasmic reticulum membrane

RYR1 RYR2

2.80e-0410532GO:0014701
GeneOntologyCellularComponentcerebellar climbing fiber to Purkinje cell synapse

GRN ITGB1

3.42e-0411532GO:0150053
GeneOntologyCellularComponentcollagen-containing extracellular matrix

TGFB2 TGFB3 SBSPON ADAMTS20 COL6A5 PLXNB2 ITGB1

3.63e-04530537GO:0062023
GeneOntologyCellularComponentchromatin silencing complex

SUV39H1 EZH2

5.63e-0414532GO:0005677
GeneOntologyCellularComponentplatelet alpha granule lumen

VEGFC TGFB2 TGFB3

6.57e-0467533GO:0031093
GeneOntologyCellularComponentfocal adhesion

LIMD1 FLRT3 FLRT2 FLRT1 ITGB1 ITGB2

7.51e-04431536GO:0005925
GeneOntologyCellularComponentESC/E(Z) complex

EZH2 DNMT3L

8.37e-0417532GO:0035098
GeneOntologyCellularComponentcell-substrate junction

LIMD1 FLRT3 FLRT2 FLRT1 ITGB1 ITGB2

8.66e-04443536GO:0030055
GeneOntologyCellularComponenthistone methyltransferase complex

KMT2C EZH2 DNMT3L

9.13e-0475533GO:0035097
GeneOntologyCellularComponentsarcolemma

TGFB3 ITGB1 RYR1 RYR2

1.37e-03190534GO:0042383
GeneOntologyCellularComponentsarcoplasmic reticulum

HRC RYR1 RYR2

1.45e-0388533GO:0016529
GeneOntologyCellularComponentasymmetric, glutamatergic, excitatory synapse

GRN ITGB1

1.68e-0324532GO:0098985
GeneOntologyCellularComponentplatelet alpha granule

VEGFC TGFB2 TGFB3

1.70e-0393533GO:0031091
GeneOntologyCellularComponentheterochromatin

SUV39H1 EZH2 DNMT3L

2.15e-03101533GO:0000792
GeneOntologyCellularComponentmethyltransferase complex

KMT2C EZH2 DNMT3L

2.60e-03108533GO:0034708
GeneOntologyCellularComponentintegrin complex

ITGB1 ITGB2

2.98e-0332532GO:0008305
GeneOntologyCellularComponentsarcoplasm

HRC RYR1 RYR2

3.03e-03114533GO:0016528
GeneOntologyCellularComponentendoplasmic reticulum membrane

RNF125 SEC24C HRC FLRT3 FLRT2 FLRT1 SPPL2C RYR1 RYR2

4.85e-031293539GO:0005789
GeneOntologyCellularComponentendoplasmic reticulum subcompartment

RNF125 SEC24C HRC FLRT3 FLRT2 FLRT1 SPPL2C RYR1 RYR2

5.00e-031299539GO:0098827
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

RNF125 SEC24C HRC FLRT3 FLRT2 FLRT1 SPPL2C RYR1 RYR2

5.74e-031327539GO:0042175
GeneOntologyCellularComponentsmooth endoplasmic reticulum

RYR1 RYR2

6.08e-0346532GO:0005790
GeneOntologyCellularComponentZ disc

HRC RYR1 RYR2

6.65e-03151533GO:0030018
GeneOntologyCellularComponentPcG protein complex

EZH2 DNMT3L

7.71e-0352532GO:0031519
GeneOntologyCellularComponentI band

HRC RYR1 RYR2

8.62e-03166533GO:0031674
GeneOntologyCellularComponentextrinsic component of cytoplasmic side of plasma membrane

RYR1 RYR2

8.90e-0356532GO:0031234
DomainSET

KMT2C SUV39H1 EZH2 SMYD3

6.76e-0641564PF00856
DomainAgouti

ASIP AGRP

8.83e-062562SM00792
DomainAgouti

ASIP AGRP

8.83e-062562PF05039
DomainAGOUTI_2

ASIP AGRP

8.83e-062562PS51150
Domain-

ASIP AGRP

8.83e-0625624.10.760.10
DomainAgouti

ASIP AGRP

8.83e-062562IPR007733
DomainAGOUTI_1

ASIP AGRP

8.83e-062562PS60024
DomainAgouti_dom

ASIP AGRP

8.83e-062562IPR027300
DomainSET

KMT2C SUV39H1 EZH2 SMYD3

1.08e-0546564SM00317
DomainSET_dom

KMT2C SUV39H1 EZH2 SMYD3

1.51e-0550564IPR001214
DomainSET

KMT2C SUV39H1 EZH2 SMYD3

1.51e-0550564PS50280
DomainRyanrecept_TM4-6

RYR1 RYR2

2.64e-053562IPR009460
DomainRyR

RYR1 RYR2

2.64e-053562PF02026
DomainRyanodine_rcpt

RYR1 RYR2

2.64e-053562IPR003032
DomainRR_TM4-6

RYR1 RYR2

2.64e-053562PF06459
DomainTGF-beta

TGFB2 TGFB3

2.64e-053562IPR016319
DomainRyan_recept

RYR1 RYR2

2.64e-053562IPR013333
DomainZnf_RING/FYVE/PHD

KMT2C RNF125 TRIM42 FGD2 ARIH2 ZFYVE26 DNMT3L MSL2

6.32e-05459568IPR013083
Domain-

SEC24C COL6A5 ITGB1 ITGB2

7.13e-05745643.40.50.410
DomainRIH_assoc

RYR1 RYR2

1.31e-046562PF08454
DomainRIH_assoc-dom

RYR1 RYR2

1.31e-046562IPR013662
DomainRIH_dom

RYR1 RYR2

1.31e-046562IPR000699
DomainIns145_P3_rcpt

RYR1 RYR2

1.31e-046562IPR014821
DomainTesmin/TSO1-like_CXC

EZH2 MSL2

1.31e-046562IPR033467
DomainIntegrin_bsu_cyt_dom

ITGB1 ITGB2

1.31e-046562IPR014836
DomainRyanodine_recept-rel

RYR1 RYR2

1.31e-046562IPR015925
DomainZF_HIT

ZNHIT2 ZNHIT3

1.31e-046562PS51083
Domain-

RYR1 RYR2

1.31e-0465621.25.10.30
Domainzf-HIT

ZNHIT2 ZNHIT3

1.31e-046562PF04438
DomainRYDR_ITPR

RYR1 RYR2

1.31e-046562PF01365
DomainZnf_HIT

ZNHIT2 ZNHIT3

1.31e-046562IPR007529
DomainCXC

EZH2 MSL2

1.31e-046562SM01114
DomainIns145_P3_rec

RYR1 RYR2

1.31e-046562PF08709
DomainIntegrin_b_cyt

ITGB1 ITGB2

1.31e-046562SM01241
DomainIntegrin_b_cyt

ITGB1 ITGB2

1.31e-046562PF08725
DomainIntegrin_bsu_tail

ITGB1 ITGB2

1.84e-047562IPR012896
DomainIntegrin_B_tail

ITGB1 ITGB2

1.84e-047562SM01242
DomainIntegrin_B_tail

ITGB1 ITGB2

1.84e-047562PF07965
DomainVWF_A

SEC24C COL6A5 ITGB1 ITGB2

2.21e-0499564IPR002035
DomainIntegrin_beta

ITGB1 ITGB2

2.44e-048562PF00362
DomainINB

ITGB1 ITGB2

2.44e-048562SM00187
DomainIntegrin_bsu_VWA

ITGB1 ITGB2

2.44e-048562IPR002369
DomainZF_RING_2

KMT2C RNF125 TRIM42 ARIH2 RNF217 MSL2

2.61e-04298566PS50089
DomainPSI

PLXNB2 ITGB1 ITGB2

3.10e-0444563IPR016201
DomainIntegrin_bsu

ITGB1 ITGB2

3.14e-049562IPR015812
DomainIntegin_beta_N

ITGB1 ITGB2

3.14e-049562IPR033760
DomainINTEGRIN_BETA

ITGB1 ITGB2

3.14e-049562PS00243
DomainPSI_integrin

ITGB1 ITGB2

3.14e-049562PF17205
DomainPSI

PLXNB2 ITGB1 ITGB2

3.54e-0446563SM00423
Domain-

KMT2C RNF125 FGD2 ARIH2 ZFYVE26 DNMT3L MSL2

3.71e-044495673.30.40.10
DomainMIR

RYR1 RYR2

3.91e-0410562PS50919
DomainMIR

RYR1 RYR2

3.91e-0410562PF02815
DomainMIR

RYR1 RYR2

3.91e-0410562SM00472
DomainE3_UB_ligase_RBR

ARIH2 RNF217

3.91e-0410562IPR031127
DomainMIR_motif

RYR1 RYR2

3.91e-0410562IPR016093
DomainLRRNT

FLRT3 FLRT2 FLRT1

5.38e-0453563PF01462
DomainTIL

MUC5B OTOG

5.72e-0412562PF01826
DomainC8

MUC5B OTOG

5.72e-0412562PF08742
DomainUnchr_dom_Cys-rich

MUC5B OTOG

6.74e-0413562IPR014853
DomainC8

MUC5B OTOG

6.74e-0413562SM00832
DomainIBR

ARIH2 RNF217

7.85e-0414562SM00647
DomainTIL_dom

MUC5B OTOG

7.85e-0414562IPR002919
DomainIBR

ARIH2 RNF217

7.85e-0414562PF01485
DomainIBR_dom

ARIH2 RNF217

9.04e-0415562IPR002867
DomainZnf_FYVE_PHD

KMT2C FGD2 ZFYVE26 DNMT3L

9.85e-04147564IPR011011
DomainPost-SET_dom

KMT2C SUV39H1

1.03e-0316562IPR003616
DomainVWD

MUC5B OTOG

1.03e-0316562SM00216
DomainPostSET

KMT2C SUV39H1

1.03e-0316562SM00508
DomainVWF_type-D

MUC5B OTOG

1.03e-0316562IPR001846
DomainVWFD

MUC5B OTOG

1.03e-0316562PS51233
DomainPOST_SET

KMT2C SUV39H1

1.03e-0316562PS50868
DomainVWD

MUC5B OTOG

1.03e-0316562PF00094
Domain-

VEGFC TGFB2 TGFB3

1.07e-03675632.10.90.10
DomainCystine-knot_cytokine

VEGFC TGFB2 TGFB3

1.07e-0367563IPR029034
DomainLIM

LIMD1 LMO1 LMO3

1.16e-0369563PF00412
Domain-

LIMD1 LMO1 LMO3

1.21e-03705632.10.110.10
DomainZnf_LIM

LIMD1 LMO1 LMO3

1.26e-0371563IPR001781
DomainLIM_DOMAIN_1

LIMD1 LMO1 LMO3

1.26e-0371563PS00478
DomainLIM_DOMAIN_2

LIMD1 LMO1 LMO3

1.26e-0371563PS50023
DomainLIM

LIMD1 LMO1 LMO3

1.26e-0371563SM00132
Domainfn3

TRIM42 FLRT3 FLRT2 FLRT1

1.41e-03162564PF00041
DomainVWC_out

MUC5B OTOG

1.46e-0319562SM00215
DomainZF_RING_1

RNF125 TRIM42 ARIH2 RNF217 MSL2

1.77e-03291565PS00518
DomainGPCR_3

GPR156 GPRC6A

1.79e-0321562IPR000337
DomainVWFA

COL6A5 ITGB1 ITGB2

1.91e-0382563PS50234
Domain7tm_3

GPR156 GPRC6A

1.96e-0322562PF00003
DomainG_PROTEIN_RECEP_F3_2

GPR156 GPRC6A

1.96e-0322562PS00980
DomainG_PROTEIN_RECEP_F3_3

GPR156 GPRC6A

1.96e-0322562PS00981
DomainG_PROTEIN_RECEP_F3_1

GPR156 GPRC6A

1.96e-0322562PS00979
DomainG_PROTEIN_RECEP_F3_4

GPR156 GPRC6A

1.96e-0322562PS50259
DomainCT

MUC5B OTOG

1.96e-0322562SM00041
DomainGPCR_3_C

GPR156 GPRC6A

1.96e-0322562IPR017978
DomainVWA

COL6A5 ITGB1 ITGB2

2.05e-0384563SM00327
DomainFN3

TRIM42 FLRT3 FLRT2 FLRT1

2.29e-03185564SM00060
DomainCys-rich_flank_reg_C

FLRT3 FLRT2 FLRT1

2.49e-0390563IPR000483
DomainLRRCT

FLRT3 FLRT2 FLRT1

2.49e-0390563SM00082
DomainIntegrin_dom

ITGB1 ITGB2

2.53e-0325562IPR032695
DomainCys_knot_C

MUC5B OTOG

2.53e-0325562IPR006207
DomainCTCK_2

MUC5B OTOG

2.53e-0325562PS01225
DomainZnf_RING

KMT2C RNF125 TRIM42 ARIH2 MSL2

2.90e-03326565IPR001841
PathwayWP_CELLTYPE_DEPENDENT_SELECTIVITY_OF_CCK2R_SIGNALING

RYR1 RYR2 CCKBR

8.50e-0613453M39589
PathwayWP_HISTONE_MODIFICATIONS

KMT2C SUV39H1 EZH2 SMYD3

5.32e-0565454M39374
PathwayBIOCARTA_CTCF_PATHWAY

TGFB2 TGFB3 CTCF

5.87e-0524453M11420
PathwayBIOCARTA_CTCF_PATHWAY

TGFB2 TGFB3 CTCF

5.87e-0524453MM1373
PathwayREACTOME_PKMTS_METHYLATE_HISTONE_LYSINES

KMT2C SUV39H1 EZH2 SMYD3

7.12e-0570454M27231
PathwayKEGG_LEISHMANIA_INFECTION

TGFB2 TGFB3 ITGB1 ITGB2

7.96e-0572454M3126
PathwayREACTOME_ECM_PROTEOGLYCANS

TGFB2 TGFB3 COL6A5 ITGB1

9.83e-0576454M27219
PathwayREACTOME_DOWNSTREAM_SIGNALING_OF_ACTIVATED_FGFR1

FLRT3 FLRT2 FLRT1

1.16e-0430453MM15236
PathwayREACTOME_DOWNSTREAM_SIGNALING_OF_ACTIVATED_FGFR1

FLRT3 FLRT2 FLRT1

1.28e-0431453M27510
PathwayKEGG_HYPERTROPHIC_CARDIOMYOPATHY_HCM

TGFB2 TGFB3 ITGB1 RYR2

1.39e-0483454M8728
PathwayREACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES

TGFB2 TGFB3 ITGB1

1.41e-0432453MM14854
PathwayKEGG_DILATED_CARDIOMYOPATHY

TGFB2 TGFB3 ITGB1 RYR2

1.89e-0490454M835
PathwayREACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES

TGFB2 TGFB3 ITGB1

2.19e-0437453M27134
PathwayREACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS

TGFB2 TGFB3 ITGB1

2.37e-0438453MM14874
PathwayWP_IMMUNE_INFILTRATION_IN_PANCREATIC_CANCER

VEGFC TGFB2 TGFB3

2.56e-0439453M46456
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

TGFB2 TGFB3 ITGB1

2.56e-0439453MM14601
PathwayKEGG_MEDICUS_REFERENCE_TGF_BETA_SIGNALING_PATHWAY

TGFB2 TGFB3

2.76e-048452M47415
PathwayKEGG_MEDICUS_REFERENCE_PLASMIN_MEDIATED_ACTIVATION_OF_LATENT_TGF_BETA

TGFB2 TGFB3

2.76e-048452M47850
PathwayBIOCARTA_LYMPHOCYTE_PATHWAY

ITGB1 ITGB2

3.54e-049452MM1534
PathwayKEGG_MEDICUS_REFERENCE_HIF_1_SIGNALING_PATHWAY

TGFB2 TGFB3

3.54e-049452M47421
PathwayBIOCARTA_LYMPHOCYTE_PATHWAY

ITGB1 ITGB2

3.54e-049452M22008
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

TGFB2 TGFB3 ITGB1

3.67e-0444453M26969
PathwayREACTOME_PKMTS_METHYLATE_HISTONE_LYSINES

SUV39H1 EZH2 SMYD3

4.19e-0446453MM14933
PathwayWP_T_CELL_MODULATION_IN_PANCREATIC_CANCER

VEGFC TGFB2 TGFB3

4.19e-0446453M46466
PathwayWP_MECHANOREGULATION_AND_PATHOLOGY_OF_YAPTAZ_VIA_HIPPO_AND_NONHIPPO_MECHANISMS

LIMD1 ITGB1 ITGB2

4.47e-0447453M39829
PathwayREACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS

TGFB2 TGFB3 ITGB1

4.47e-0447453M646
PathwayREACTOME_SIGNALING_BY_FGFR1

FLRT3 FLRT2 FLRT1

5.36e-0450453MM15255
PathwayBIOCARTA_MONOCYTE_PATHWAY

ITGB1 ITGB2

5.38e-0411452MM1436
PathwayKEGG_MEDICUS_REFERENCE_CA2_CAM_VGCC_RYR_SIGNALING_PATHWAY

RYR1 RYR2

5.38e-0411452M47958
PathwayBIOCARTA_MONOCYTE_PATHWAY

ITGB1 ITGB2

5.38e-0411452M4956
PathwayREACTOME_SIGNALING_BY_FGFR1

FLRT3 FLRT2 FLRT1

6.02e-0452453M27530
PathwayWP_11P112_COPY_NUMBER_VARIATION_SYNDROME

ITGB1 ITGB2 SPPL2C

7.49e-0456453M48075
PathwayKEGG_MEDICUS_VARIANT_LOSS_OF_VHL_TO_HIF_1_SIGNALING_PATHWAY

TGFB2 TGFB3

8.85e-0414452M47422
PathwayBIOCARTA_LYM_PATHWAY

ITGB1 ITGB2

8.85e-0414452M1469
PathwayBIOCARTA_ERYTH_PATHWAY

TGFB2 TGFB3

1.02e-0315452M9367
PathwayBIOCARTA_TGFB_PATHWAY

TGFB2 TGFB3

1.31e-0317452MM1509
PathwayWP_CELLS_AND_MOLECULES_INVOLVED_IN_LOCAL_ACUTE_INFLAMMATORY_RESPONSE

ITGB1 ITGB2

1.31e-0317452M39733
PathwayWP_PLATELETMEDIATED_INTERACTIONS_WITH_VASCULAR_AND_CIRCULATING_CELLS

TGFB2 TGFB3

1.31e-0317452M39807
PathwayBIOCARTA_LAIR_PATHWAY

ITGB1 ITGB2

1.31e-0317452M3952
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

SBSPON ADAMTS20 MUC5B

1.32e-0368453M27303
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

TGFB2 TGFB3 COL6A5 ITGB1 ITGB2

1.33e-03258455MM14572
PathwayKEGG_RENAL_CELL_CARCINOMA

VEGFC TGFB2 TGFB3

1.43e-0370453M13266
PathwayKEGG_PANCREATIC_CANCER

VEGFC TGFB2 TGFB3

1.43e-0370453M9726
PathwayBIOCARTA_ERYTH_PATHWAY

TGFB2 TGFB3

1.48e-0318452MM1392
PathwayBIOCARTA_TGFB_PATHWAY

TGFB2 TGFB3

1.65e-0319452M18933
PathwayKEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

RYR1 RYR2

1.65e-0319452M47760
PathwayBIOCARTA_TOB1_PATHWAY

TGFB2 TGFB3

1.65e-0319452M18215
PathwayBIOCARTA_TOB1_PATHWAY

TGFB2 TGFB3

1.65e-0319452MM1490
PathwayREACTOME_CHROMATIN_MODIFYING_ENZYMES

KMT2C SUV39H1 EZH2 SMYD3 MSL2

1.68e-03272455M29619
PathwayWP_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_IN_COLORECTAL_CANCER

TGFB2 TGFB3 WNT9A EZH2

1.70e-03161454M39770
PathwayREACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS

COL6A5 ITGB1 ITGB2

1.82e-0376453MM14867
PathwayREACTOME_SIGNALING_BY_FGFR

FLRT3 FLRT2 FLRT1

1.89e-0377453MM14722
PathwayREACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX

TGFB2 TGFB3 ITGB1

1.89e-0377453MM14670
PathwayREACTOME_SIGNALING_BY_RECEPTOR_TYROSINE_KINASES

VEGFC COL6A5 FLRT3 FLRT2 FLRT1 ITGB1

2.01e-03418456MM15587
PathwayREACTOME_CHROMATIN_MODIFYING_ENZYMES

SUV39H1 EZH2 SMYD3 MSL2

2.30e-03175454MM14941
PathwayREACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS

COL6A5 ITGB1 ITGB2

2.50e-0385453M16441
PathwayWP_PLEURAL_MESOTHELIOMA

VEGFC KMT2C LIMD1 EZH2 ITGB1 ITGB2

2.57e-03439456M42563
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

TGFB2 TGFB3 COL6A5 ITGB1 ITGB2

2.57e-03300455M610
PathwayREACTOME_SIGNALING_BY_FGFR

FLRT3 FLRT2 FLRT1

2.85e-0389453M1090
PathwayPID_INTEGRIN_A9B1_PATHWAY

VEGFC ITGB1

2.85e-0325452M118
PathwayPID_LYMPH_ANGIOGENESIS_PATHWAY

VEGFC ITGB1

2.85e-0325452M274
PathwayBIOCARTA_NKT_PATHWAY

TGFB2 TGFB3

3.08e-0326452M4047
PathwayPID_INTEGRIN_CS_PATHWAY

ITGB1 ITGB2

3.08e-0326452M47
PathwayPID_GLYPICAN_1PATHWAY

TGFB2 TGFB3

3.32e-0327452M33
PathwayREACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX

TGFB2 TGFB3 ITGB1

3.33e-0394453M1041
PathwayBIOCARTA_G1_PATHWAY

TGFB2 TGFB3

3.57e-0328452M648
PathwayKEGG_PATHWAYS_IN_CANCER

VEGFC TGFB2 TGFB3 WNT9A ITGB1

3.62e-03325455M12868
PathwayWP_SELECTIVE_EXPRESSION_OF_CHEMOKINE_RECEPTORS_DURING_TCELL_POLARIZATION

TGFB2 TGFB3

3.83e-0329452M39797
PathwayWP_EXTRACELLULAR_VESICLEMEDIATED_SIGNALING_IN_RECIPIENT_CELLS

TGFB2 TGFB3

3.83e-0329452M39516
PathwayBIOCARTA_INFLAM_PATHWAY

TGFB2 TGFB3

3.83e-0329452M6910
PathwayBIOCARTA_G1_PATHWAY

TGFB2 TGFB3

3.83e-0329452MM1364
PathwayBIOCARTA_IL1R_PATHWAY

TGFB2 TGFB3

4.37e-0331452M12095
PathwayBIOCARTA_P38MAPK_PATHWAY

TGFB2 TGFB3

4.65e-0332452MM1450
PathwayBIOCARTA_NKT_PATHWAY

TGFB2 TGFB3

4.65e-0332452MM1492
PathwayWP_COMPLEMENT_SYSTEM_IN_NEURONAL_DEVELOPMENT_AND_PLASTICITY

TGFB2 TGFB3 ITGB2

4.66e-03106453M42535
PathwayWP_SIGNAL_TRANSDUCTION_THROUGH_IL1R

TGFB2 TGFB3

4.94e-0333452M39803
PathwayBIOCARTA_INFLAM_PATHWAY

TGFB2 TGFB3

4.94e-0333452MM1379
PathwayREACTOME_O_LINKED_GLYCOSYLATION

SBSPON ADAMTS20 MUC5B

5.04e-03109453MM15164
PathwayWP_TYPE_2_PAPILLARY_RENAL_CELL_CARCINOMA

TGFB2 TGFB3

5.24e-0334452M39771
PathwayREACTOME_O_LINKED_GLYCOSYLATION

SBSPON ADAMTS20 MUC5B

5.30e-03111453M27416
PathwayBIOCARTA_P38MAPK_PATHWAY

TGFB2 TGFB3

5.86e-0336452M862
PathwayBIOCARTA_ALK_PATHWAY

TGFB2 TGFB3

6.18e-0337452M17400
PathwayWP_NEOVASCULARIZATION_PROCESSES

TGFB2 TGFB3

6.18e-0337452M39506
PathwayREACTOME_SIGNALING_BY_TGFB_FAMILY_MEMBERS

TGFB2 TGFB3 ITGB1

6.28e-03118453MM15588
PathwayREACTOME_SIGNALING_BY_RECEPTOR_TYROSINE_KINASES

VEGFC COL6A5 FLRT3 FLRT2 FLRT1 ITGB1

6.55e-03532456M27870
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

SBSPON ADAMTS20

6.85e-0339452M27417
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

SBSPON ADAMTS20

6.85e-0339452MM15165
PathwayREACTOME_ACTIVATION_OF_ANTERIOR_HOX_GENES_IN_HINDBRAIN_DEVELOPMENT_DURING_EARLY_EMBRYOGENESIS

KMT2C CTCF EZH2

6.89e-03122453M29689
Pubmed

Identification of FLRT1, FLRT2, and FLRT3: a novel family of transmembrane leucine-rich repeat proteins.

FLRT3 FLRT2 FLRT1

3.95e-09356310644439
Pubmed

FLRT3 Marks Direction-Selective Retinal Ganglion Cells That Project to the Medial Terminal Nucleus.

FLRT3 FLRT2 FLRT1

1.58e-08456334955746
Pubmed

Regulated expression of FLRT genes implies a functional role in the regulation of FGF signalling during mouse development.

FLRT3 FLRT2 FLRT1

1.58e-08456316872596
Pubmed

Structural Basis of Teneurin-Latrophilin Interaction in Repulsive Guidance of Migrating Neurons.

FLRT3 FLRT2 FLRT1

1.58e-08456331928845
Pubmed

Localization of extracellular matrix molecules, integrins and their regulators, TGF betas, is correlated with axon pathfinding in the spinal cord of normal and Danforth's short tail mice.

TGFB2 TGFB3 ITGB1

1.38e-0775639427478
Pubmed

The testis-specific factor CTCFL cooperates with the protein methyltransferase PRMT7 in H19 imprinting control region methylation.

CTCFL CTCF DNMT3L

4.71e-071056317048991
Pubmed

Cartography of teneurin and latrophilin expression reveals spatiotemporal axis heterogeneity in the mouse hippocampus during development.

FLRT3 FLRT2 FLRT1

4.71e-071056338713721
Pubmed

Single-cell profiling of epigenetic modifiers identifies PRDM14 as an inducer of cell fate in the mammalian embryo.

KMT2C SUV39H1 EZH2 DNMT3L

7.80e-074456424183668
Pubmed

FLRT2 and FLRT3 act as repulsive guidance cues for Unc5-positive neurons.

FLRT3 FLRT2 FLRT1

8.61e-071256321673655
Pubmed

Regulation of Cerebral Cortex Folding by Controlling Neuronal Migration via FLRT Adhesion Molecules.

FLRT3 FLRT2 FLRT1

1.12e-061356328475893
Pubmed

Ventral closure, headfold fusion and definitive endoderm migration defects in mouse embryos lacking the fibronectin leucine-rich transmembrane protein FLRT3.

FLRT3 FLRT2 FLRT1

1.12e-061356318448090
Pubmed

An extracellular biochemical screen reveals that FLRTs and Unc5s mediate neuronal subtype recognition in the retina.

FLRT3 FLRT2 FLRT1 PLXNB2

1.54e-065256426633812
Pubmed

The fibronectin leucine-rich repeat transmembrane protein Flrt2 is required in the epicardium to promote heart morphogenesis.

FLRT3 FLRT2 ITGB1

2.18e-061656321350012
Pubmed

CTCF and CTCFL in cancer.

CTCFL CTCF

2.55e-06256232334335
Pubmed

Starvation after AgRP neuron ablation is independent of melanocortin signaling.

ASIP AGRP

2.55e-06256218272480
Pubmed

Skeletal and cardiac ryanodine receptors exhibit different responses to Ca2+ overload and luminal ca2+.

RYR1 RYR2

2.55e-06256217259277
Pubmed

Defining the relative and combined contribution of CTCF and CTCFL to genomic regulation.

CTCFL CTCF

2.55e-06256232393311
Pubmed

Ryanodine receptor oligomeric interaction: identification of a putative binding region.

RYR1 RYR2

2.55e-06256214722100
Pubmed

Structural and functional interactions within ryanodine receptor.

RYR1 RYR2

2.55e-06256226009179
Pubmed

Dissecting Integrin Expression and Function on Memory B Cells in Mice and Humans in Autoimmunity.

ITGB1 ITGB2

2.55e-06256230949178
Pubmed

Structure and Function of the Human Ryanodine Receptors and Their Association with Myopathies-Present State, Challenges, and Perspectives.

RYR1 RYR2

2.55e-06256232899693
Pubmed

Integrin beta1-mediated signaling is involved in transforming growth factor-beta2-promoted migration in human lens epithelial cells.

TGFB2 ITGB1

2.55e-06256217960115
Pubmed

Immunohistochemical localization of members of the transforming growth factor (TGF)-beta superfamily in normal human salivary glands and pleomorphic adenomas.

TGFB2 TGFB3

2.55e-06256211488419
Pubmed

Agouti and agouti-related protein: analogies and contrasts.

ASIP AGRP

2.55e-06256210702221
Pubmed

Correlations of EZH2 and SMYD3 gene polymorphisms with breast cancer susceptibility and prognosis.

EZH2 SMYD3

2.55e-06256229089464
Pubmed

Platelet binding to monocytes increases the adhesive properties of monocytes by up-regulating the expression and functionality of beta1 and beta2 integrins.

ITGB1 ITGB2

2.55e-06256216415171
Pubmed

Discovering a binary CTCF code with a little help from BORIS.

CTCFL CTCF

2.55e-06256229077515
Pubmed

beta1 and beta2 integrins activate different signalling pathways in monocytes.

ITGB1 ITGB2

2.55e-06256211931654
Pubmed

BORIS and CTCF are overexpressed in squamous intraepithelial lesions and cervical cancer.

CTCFL CTCF

2.55e-06256226125810
Pubmed

The arrhythmogenic human HRC point mutation S96A leads to spontaneous Ca(2+) release due to an impaired ability to buffer store Ca(2+).

HRC RYR2

2.55e-06256224805197
Pubmed

Expression of transforming growth factor-beta isoforms (beta 2 and beta 3) in the mouse uterus: analysis of the periimplantation period and effects of ovarian steroids.

TGFB2 TGFB3

2.55e-0625621375903
Pubmed

The cancer-testis antigen BORIS phenocopies the tumor suppressor CTCF in normal and neoplastic cells.

CTCFL CTCF

2.55e-06256223553099
Pubmed

Ryanodine receptors in human pancreatic beta cells: localization and effects on insulin secretion.

RYR1 RYR2

2.55e-06256215033925
Pubmed

Testis-specific transcriptional regulators selectively occupy BORIS-bound CTCF target regions in mouse male germ cells.

CTCFL CTCF

2.55e-06256228145452
Pubmed

The role of the specificity-determining loop of the integrin beta subunit I-like domain in autonomous expression, association with the alpha subunit, and ligand binding.

ITGB1 ITGB2

2.55e-06256211914080
Pubmed

Disease-related quantitation of TGF-beta3 in human aqueous humor.

TGFB2 TGFB3

2.55e-06256218049952
Pubmed

The novel BORIS + CTCF gene family is uniquely involved in the epigenetics of normal biology and cancer.

CTCFL CTCF

2.55e-06256212191639
Pubmed

Short-chain fatty acids from periodontal pathogens suppress histone deacetylases, EZH2, and SUV39H1 to promote Kaposi's sarcoma-associated herpesvirus replication.

SUV39H1 EZH2

2.55e-06256224501407
Pubmed

SMYD3 regulates gastric cancer progression and macrophage polarization through EZH2 methylation.

EZH2 SMYD3

2.55e-06256236127410
Pubmed

The male germ cell gene regulator CTCFL is functionally different from CTCF and binds CTCF-like consensus sites in a nucleosome composition-dependent manner.

CTCFL CTCF

2.55e-06256222709888
Pubmed

Ablation of neurons expressing agouti-related protein activates fos and gliosis in postsynaptic target regions.

ASIP AGRP

2.55e-06256218784302
Pubmed

Recent advances in understanding the ryanodine receptor calcium release channels and their role in calcium signalling.

RYR1 RYR2

2.55e-06256230542613
Pubmed

The combined action of CTCF and its testis-specific paralog BORIS is essential for spermatogenesis.

CTCFL CTCF

2.55e-06256234158481
Pubmed

Decreased stroma adhesion capacity of CD34+ progenitor cells from mobilized peripheral blood is not lineage- or stage-specific and is associated with low beta 1 and beta 2 integrin expression.

ITGB1 ITGB2

2.55e-06256212183834
Pubmed

Ryanodine receptors are expressed and functionally active in mouse spermatogenic cells and their inhibition interferes with spermatogonial differentiation.

RYR1 RYR2

2.55e-06256215280431
Pubmed

Expression of the ryanodine receptor isoforms in immune cells.

RYR1 RYR2

2.55e-06256211673493
Pubmed

Epigenetic-related gene expression profile in medullary thyroid cancer revealed the overexpression of the histone methyltransferases EZH2 and SMYD3 in aggressive tumours.

EZH2 SMYD3

2.55e-06256224813658
Pubmed

B-lymphocytes from malignant hyperthermia-susceptible patients have an increased sensitivity to skeletal muscle ryanodine receptor activators.

RYR1 RYR2

2.55e-06256211673462
Pubmed

BORIS, a novel male germ-line-specific protein associated with epigenetic reprogramming events, shares the same 11-zinc-finger domain with CTCF, the insulator protein involved in reading imprinting marks in the soma.

CTCFL CTCF

2.55e-06256212011441
Pubmed

Crystal structures of wild type and disease mutant forms of the ryanodine receptor SPRY2 domain.

RYR1 RYR2

2.55e-06256225370123
Pubmed

The role of transforming growth factor beta-2, beta-3 in mediating apoptosis in the murine intestinal mucosa.

TGFB2 TGFB3

2.55e-06256211984523
Pubmed

Thermodynamics of calmodulin binding to cardiac and skeletal muscle ryanodine receptor ion channels.

RYR1 RYR2

2.55e-06256218618700
Pubmed

TGF-beta-1 up-regulates extra-cellular matrix production in mouse hepatoblasts.

TGFB2 TGFB3 ITGB1

3.17e-061856323041440
Pubmed

Chromosomal localization of seven members of the murine TGF-beta superfamily suggests close linkage to several morphogenetic mutant loci.

TGFB2 TGFB3 ASIP

5.15e-06215631970330
Pubmed

Studies of TGF-beta(1-3) in serosal fluid during abdominal surgery and their effect on in vitro human mesothelial cell proliferation.

TGFB2 TGFB3

7.63e-06356219062040
Pubmed

Activity-dependent release of transforming growth factor-beta in a neuronal network in vitro.

TGFB2 TGFB3

7.63e-06356217997227
Pubmed

Type 1 and type 3 ryanodine receptors are selectively involved in muscarinic antinociception in mice: an antisense study.

RYR1 RYR2

7.63e-06356218403125
Pubmed

A biochemical function for attractin in agouti-induced pigmentation and obesity.

ASIP AGRP

7.63e-06356211137996
Pubmed

TGF-beta knockout and dominant-negative receptor transgenic mice.

TGFB2 TGFB3

7.63e-0635629525700
Pubmed

Integrating role of T antigen, Rb2/p130, CTCF and BORIS in mediating non-canonical endoplasmic reticulum-dependent death pathways triggered by chronic ER stress in mouse medulloblastoma.

CTCFL CTCF

7.63e-06356222544282
Pubmed

Differential expression of transforming growth factor-beta isoforms in bullous keratopathy corneas.

TGFB2 TGFB3

7.63e-06356220142847
Pubmed

TGF-beta is required for programmed cell death in interdigital webs of the developing mouse limb.

TGFB2 TGFB3

7.63e-06356211960699
Pubmed

Effects of AgRP inhibition on energy balance and metabolism in rodent models.

ASIP AGRP

7.63e-06356223762342
Pubmed

Activation of Epac stimulates integrin-dependent homing of progenitor cells.

ITGB1 ITGB2

7.63e-06356218032709
Pubmed

The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues.

RYR1 RYR2

7.63e-0635627876312
Pubmed

Posttraumatic temporal TGF-β mRNA expression in lens epithelial cells of paediatric patients.

TGFB2 TGFB3

7.63e-06356222464821
Pubmed

Dendritic differentiation of cerebellar Purkinje cells is promoted by ryanodine receptors expressed by Purkinje and granule cells.

RYR1 RYR2

7.63e-06356224123915
Pubmed

Expression of transforming growth factor-beta 1, -beta 2, and -beta 3 in human developing teeth: immunolocalization according to the odontogenesis phases.

TGFB2 TGFB3

7.63e-06356218078367
Pubmed

Excess TGF-β mediates muscle weakness associated with bone metastases in mice.

TGFB2 TGFB3

7.63e-06356226457758
Pubmed

Specific transforming growth factor-beta subtypes regulate embryonic mouse Meckel's cartilage and tooth development.

TGFB2 TGFB3

7.63e-0635628125201
Pubmed

Experimental manipulation of transforming growth factor-beta isoforms significantly affects adhesion formation in a murine surgical model.

TGFB2 TGFB3

7.63e-06356216192636
Pubmed

Differential expression of TGF beta isoforms in murine palatogenesis.

TGFB2 TGFB3

7.63e-0635622401212
Pubmed

Tgfbeta2 and 3 are coexpressed with their extracellular regulator Ltbp1 in the early limb bud and modulate mesodermal outgrowth and BMP signaling in chicken embryos.

TGFB2 TGFB3

7.63e-06356220565961
Pubmed

Isoform-specific effects of transforming growth factor β on endothelial-to-mesenchymal transition.

TGFB2 TGFB3

7.63e-06356229856065
Pubmed

Transforming growth factor-beta gene polymorphisms in sarcoidosis patients with and without fibrosis.

TGFB2 TGFB3

7.63e-06356216778279
Pubmed

Dopamine D1 receptor signaling system regulates ryanodine receptor expression in ethanol physical dependence.

RYR1 RYR2

7.63e-06356223278119
Pubmed

Synergistic effects of TGFβ2, WNT9a, and FGFR4 signals attenuate satellite cell differentiation during skeletal muscle development.

TGFB2 WNT9A

7.63e-06356229869452
Pubmed

Transforming growth factor beta (TGFbeta1, TGFbeta2 and TGFbeta3) null-mutant phenotypes in embryonic gonadal development.

TGFB2 TGFB3

7.63e-06356218790002
Pubmed

Transforming growth factor-beta isoform and receptor expression in chondrosarcoma of bone.

TGFB2 TGFB3

7.63e-06356212021923
Pubmed

Bidirectional coupling between ryanodine receptors and Ca2+ release-activated Ca2+ (CRAC) channel machinery sustains store-operated Ca2+ entry in human T lymphocytes.

RYR1 RYR2

7.63e-06356222948152
Pubmed

Characterization of L-plastin interaction with beta integrin and its regulation by micro-calpain.

ITGB1 ITGB2

7.63e-06356220183869
Pubmed

Differential expression of TGFβ isoforms in breast cancer highlights different roles during breast cancer progression.

TGFB2 TGFB3

7.63e-06356229320969
Pubmed

Relationship between Axial Length and Levels of TGF-β in the Aqueous Humor and Plasma of Myopic Patients.

TGFB2 TGFB3

7.63e-06356233728344
Pubmed

Aberrant TGFβ Signaling Contributes to Altered Trophoblast Differentiation in Preeclampsia.

TGFB2 TGFB3

7.63e-06356226653761
Pubmed

In situ hybridization analysis of TGF beta 3 RNA expression during mouse development: comparative studies with TGF beta 1 and beta 2.

TGFB2 TGFB3

7.63e-0635621723948
Pubmed

Developmental changes in expression of the three ryanodine receptor mRNAs in the mouse brain.

RYR1 RYR2

7.63e-06356210788707
Pubmed

Localization and binding of transforming growth factor-beta isoforms in mouse preimplantation embryos and in delayed and activated blastocysts.

TGFB2 TGFB3

7.63e-0635621577201
Pubmed

Transforming growth factor-beta. A family of growth regulatory peptides.

TGFB2 TGFB3

7.63e-0635622375595
Pubmed

Ca(2+)-induced Ca2+ release in myocytes from dyspedic mice lacking the type-1 ryanodine receptor.

RYR1 RYR2

7.63e-0635627621815
Pubmed

Embryonic gene expression patterns of TGF beta 1, beta 2 and beta 3 suggest different developmental functions in vivo.

TGFB2 TGFB3

7.63e-0635621707784
Pubmed

alpha subunit partners to beta1 and beta2 integrins during IL-4-induced foreign body giant cell formation.

ITGB1 ITGB2

7.63e-06356217311314
Pubmed

Null mutation of the Lmo4 gene or a combined null mutation of the Lmo1/Lmo3 genes causes perinatal lethality, and Lmo4 controls neural tube development in mice.

LMO1 LMO3

7.63e-06356214966285
Pubmed

Wiz binds active promoters and CTCF-binding sites and is required for normal behaviour in the mouse.

CTCF ASIP

7.63e-06356227410475
Pubmed

Developing human minor salivary glands: morphological parallel relation between the expression of TGF-beta isoforms and cytoskeletal markers of glandular maturation.

TGFB2 TGFB3

7.63e-06356218080134
Pubmed

High immunoexpression of Ki67, EZH2, and SMYD3 in diagnostic prostate biopsies independently predicts outcome in patients with prostate cancer.

EZH2 SMYD3

7.63e-06356229174711
Pubmed

CCCTC-Binding Factor Mediates the Transcription of Insulin-Like Growth Factor Binding Protein 5 Through EZH2 in Ulcerative Colitis.

CTCF EZH2

7.63e-06356235705732
Pubmed

Ablation of HRC alleviates cardiac arrhythmia and improves abnormal Ca handling in CASQ2 knockout mice prone to CPVT.

HRC RYR2

7.63e-06356226410369
Pubmed

Molecular identification of the ryanodine receptor pore-forming segment.

RYR1 RYR2

7.63e-06356210473538
Pubmed

Circulating levels of transforming growth factor beta-1, 2 and 3 in HIV associated preeclamptic pregnancies.

TGFB2 TGFB3

7.63e-06356236006052
Pubmed

Regulation of proliferation, motility, and contractivity of cultured human endometrial stromal cells by transforming growth factor-beta isoforms.

TGFB2 TGFB3

7.63e-06356216210002
InteractionUNC5D interactions

FLRT3 FLRT2 FLRT1

1.01e-068543int:UNC5D
InteractionUNC5A interactions

FLRT3 FLRT2 FLRT1

1.51e-069543int:UNC5A
GeneFamilyZinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family

KMT2C SUV39H1 EZH2 SMYD3

1.11e-0634424487
GeneFamilyRyanodine receptors|Protein phosphatase 1 regulatory subunits

RYR1 RYR2

1.58e-053422287
GeneFamilyZinc fingers HIT-type

ZNHIT2 ZNHIT3

7.86e-05642283
GeneFamilyCD molecules|Integrin beta subunits

ITGB1 ITGB2

1.88e-0494221159
GeneFamilyLIM domain containing

LIMD1 LMO1 LMO3

3.46e-04594231218
GeneFamilyFibronectin type III domain containing

TRIM42 FLRT3 FLRT2 FLRT1

5.09e-04160424555
GeneFamilyZinc fingers FYVE-type|Pleckstrin homology domain containing|Rho guanine nucleotide exchange factors

FGD2 ZFYVE26

2.35e-033142281
GeneFamilyRing finger proteins

RNF125 TRIM42 RNF217 MSL2

3.72e-0327542458
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

CSRNP2 TRIM42 RYR1

8.51e-03181423694
GeneFamilyEndogenous ligands

TGFB2 TGFB3 AGRP

1.75e-02237423542
CoexpressionNABA_MATRISOME

VEGFC TGFB2 TGFB3 SBSPON WNT9A OGFOD2 ADAMTS20 COL6A5 MUC5B PLXNB2 OTOG

7.84e-0610085611MM17056
CoexpressionNABA_MATRISOME

VEGFC TGFB2 TGFB3 SBSPON WNT9A OGFOD2 ADAMTS20 COL6A5 MUC5B PLXNB2 OTOG

9.27e-0610265611M5889
ToppCellP15-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

LMO1 SBSPON ADAMTS20 FLRT3 FLRT1

2.81e-06176565792f414f5092aba14260b8e16378e793a822498e
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

KMT2C ADAMTS20 GPRC6A FLRT2 RYR2

3.68e-0618656523b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TGFB2 LIMD1 SBSPON LMO3 FLRT3

3.88e-06188565e9cef856a96a97afac5ecafe2ee91eff0d731e01
ToppCellfacs-Trachea-3m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_tracheal_l15|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FGD2 FLRT3 ITGB2 RYR1

5.39e-051645645ca7b69684a8bb12dd0b45e7ad94e30d16ed01ce
ToppCellfacs-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-myeloid_dendritic_type_1|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FGD2 LMO1 ITGB2 RYR1

6.20e-051705646686d1797988216c0d9417f21a2537369abce410
ToppCelldroplet-Trachea-3m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_tracheal_l15|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FGD2 FLRT3 ITGB2 RYR1

6.34e-0517156487cb65648c663e246f94cea1a5ed12e8e29ec629
ToppCelldroplet-Kidney-nan-21m-Lymphocytic-lymphocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FGD2 LMO1 ITGB2 RYR1

6.34e-051715640385d5834ae16bbb0c6a68893fec60e4dd1e478d
ToppCelldroplet-Thymus-nan-3m-Myeloid|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VEGFC FGD2 LMO1 DNMT3L

6.34e-0517156425493a4a7b636920e2cfd984542cc500709c9dcf
ToppCelldroplet-Kidney-nan-21m-Lymphocytic-CD45|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FGD2 LMO1 ITGB2 RYR1

6.34e-05171564a3e3fe0cbab21abb178c482f5951e576529f7e30
ToppCelldroplet-Thymus-nan-3m-Myeloid-professional_antigen_presenting_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VEGFC FGD2 LMO1 DNMT3L

6.34e-05171564508b41e3ad2638f9dd546d251b13ff60fc8c3207
ToppCellLymphoid-Lymphoid-B_cells_(cycle)|Lymphoid / shred on cell class and cell subclass (v4)

SUV39H1 GRN EZH2 RYR1

6.49e-05172564f39822afcc35f0fbf68b8ffd1894e4b6c8d7a80c
ToppCellfacs-Trachea-18m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_tracheal_l15|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FGD2 FLRT3 ITGB2 RYR1

6.49e-05172564eaba10a4d4eaab42ad2e2da65ebb20b50edaf815
ToppCell11.5-Distal-Mesenchymal-Mesenchyme_SERPINF1-high|Distal / Age, Tissue, Lineage and Cell class

TGFB3 CTCFL LMO1 SBSPON

6.63e-051735646989c9cebcd81eccceac7e5a86152676ee959386
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.5.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FGD2 ZFYVE26 GRN ITGB2

6.78e-05174564d5c22b43531414951666ee7542a66ed9380e2d14
ToppCellfacs-Trachea-24m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_tracheal_l15|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FGD2 FLRT3 ITGB2 RYR1

6.78e-05174564c52aed2ffe9c648e5f23e3459e2d331d6ca214e3
ToppCellAT1_cells-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

TGFB2 SBSPON WNT9A FLRT3

7.09e-051765644a30bb771297b30926fb98e2b5ec0dbdc46feac7
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

AGRP BRI3 GRN ITGB2

7.25e-05177564382f0d6bbff01e84b0c7840e74ac865864e6da89
ToppCellfacs-Lung-EPCAM-3m-Myeloid-myeloid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FGD2 LMO1 ITGB2 RYR1

7.25e-05177564e73e2b6a72630bb56ac2af1cdeedc8f0f828f390
ToppCellfacs-Lung-24m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25-31|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SBSPON ADAMTS20 LMO3 FLRT1

7.25e-051775646b4fe717928814dafcd13090b1c90ea973938c6d
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.6.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FGD2 AGRP BRI3 GRN

7.25e-05177564929cd8f530ce001623735da53b7278d02522e2b5
ToppCellfacs-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FGD2 LMO1 ITGB2 RYR1

7.57e-0517956433ed9270d257895ff3b40df2c1af878119c9f492
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Myeloid-Dendritic-conventional_dendritic_cell-DC_c2-CD1C|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

FGD2 BRI3 GRN PLXNB2

7.74e-051805642bc3fd2e4c249bf236340c5f0483747faa5c04ec
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Myeloid-Dendritic-conventional_dendritic_cell|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

FGD2 BRI3 GRN PLXNB2

7.90e-051815641b4eb044825ede6361928442524b1988c8ef58b3
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFB2 WNT9A ADAMTS20 RNF217

7.90e-051815647af469f5bcb9b1ab3f35b2758bf2afb87e8eba57
ToppCellcellseq2-Immune-Immune_Myeloid-AM|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

AGRP BRI3 GRN ITGB2

7.90e-05181564d4ab8ab41bf3e6f1937e919662456d7c9551eeab
ToppCellcellseq2-Immune-Immune_Myeloid-AM-AM|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

AGRP BRI3 GRN ITGB2

7.90e-0518156445fc9c27ea60312a118a2a6c1eb635d776fde295
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Myeloid-Dendritic|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

FGD2 BRI3 GRN PLXNB2

7.90e-051815648d7ebbedc373d55e29da02ac2728b4f4118038f2
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Dendritic-conventional_dendritic_cell-DC_c2-CD1C|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

OGFOD2 GRN PLXNB2 ITGB2

7.90e-05181564c8286a7ac8e3cc5aa7e92b043a08435294ea686f
ToppCellfacs-Lung-EPCAM-24m-Myeloid-myeloid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FGD2 LMO1 ITGB2 RYR1

8.07e-051825649465238ac806fce46dfe1a141e83893f23eb4afb
ToppCellCOVID-19-lung-AT1|lung / Disease (COVID-19 only), tissue and cell type

TGFB2 WNT9A LMO3 FLRT3

8.25e-05183564942530449e9c6583705eeb8f6f12621daea57252
ToppCellfacs-Lung-EPCAM-24m-Myeloid-Myeloid_Dendritic_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FGD2 LMO1 ITGB2 RYR1

8.25e-05183564107cc756c45d6e92181659868d91188814dae66d
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS20 MUC5B RYR2 OTOG

8.42e-051845642cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS20 MUC5B RYR2 OTOG

8.42e-05184564ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS20 MUC5B RYR2 OTOG

8.42e-051845642b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

FGD2 BRI3 GRN PLXNB2

8.42e-05184564bc0dfe29337f02594e7e0092c9e47dda94b45ad5
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SBSPON WNT9A FLRT2 ITGB1

9.15e-051885644d1e5f85342ae550086609d7680e32730b78b5d2
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LIMD1 FGD2 ITGB2 RYR1

9.15e-05188564cb091912f9b627a78a8793a37df7f1de839f887f
ToppCelldroplet-Heart-HEART-1m-Neuronal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SBSPON ADAMTS20 FLRT3 FLRT1

9.34e-05189564a618a1ddf5097a010c6c2c7341f3a0bd46a29c02
ToppCelldroplet-Heart-HEART-1m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SBSPON ADAMTS20 FLRT3 FLRT1

9.34e-051895644e61f9cd1c06bddb47ebf98affc0f97770e26e8c
ToppCelldroplet-Tongue-nan-3m-Epithelial-filiform|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFB2 FGD2 LMO1 RYR1

9.53e-05190564251e3a33041023bfc4b547c7eb68cfb8f421636f
ToppCelldroplet-Tongue-TONGUE-1m-Epithelial-filiform|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFB2 FGD2 FLRT1 RYR1

9.53e-051905648a53f4d3c9aca45b5826f53f7dcdfb8bc8280acb
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Myeloid-Macrophages|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FGD2 BRI3 GRN ITGB2

9.73e-0519156494c7da03e5264f4d73bb507ce339a935d90279a0
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FGD2 BRI3 GRN ITGB2

9.73e-05191564b5715eeb72a97b7bc87b83f6c289e225f58da842
ToppCellfacs-Aorta-Heart-3m-Mesenchymal|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFB2 TGFB3 FLRT2 PLXNB2

9.92e-051925640dc1f46e40346ed0b286e53b106a812441575100
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AGRP ZFYVE26 GRN ITGB2

1.01e-0419356450c2832de75b6469f649355c6b9a75e910d32db3
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.5.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AGRP ZFYVE26 GRN ITGB2

1.01e-04193564222829c30ebe47f0ed1e035897e3cd4be10b2a11
ToppCell5'-Adult-SmallIntestine-Hematopoietic-Myeloid-Macrophages|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FGD2 GRN ITGB2 RYR1

1.03e-041945647c7091de47359760003e910cfbe63db5c99410d6
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar-AT1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TGFB2 WNT9A LMO3 FLRT3

1.05e-04195564a71ba5e4043e2d35a45a2c60a96b087e31832345
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Dendritic|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

FGD2 ASIP GRN RYR1

1.05e-041955644cbc36fb3ef9aef61367d3b37070a9a85fae1418
ToppCell(1)_Osterolineage_cells-(11)_OLC-2|World / Cell class and subclass of bone marrow stroma cells in homeostatis

TGFB2 TGFB3 COL6A5 FLRT2

1.05e-0419556478978d85273e5463a7f43e4c121e647fa6aba42b
ToppCell10x5'-blood-Myeloid_Monocytic-Nonclassical_monocytes|blood / Manually curated celltypes from each tissue

FGD2 BRI3 GRN PLXNB2

1.05e-0419556488d65c7c3a28922c125bd9f7c403a55d7d4d83a9
ToppCellILEUM-non-inflamed-(9)_Enteric_neurons|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

TGFB2 SBSPON FLRT3 FLRT1

1.07e-04196564998aa523555ed6bc9c1b5cacbf7ba77c7b218e6b
ToppCellILEUM-non-inflamed-(9)_Neuro_cell|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

TGFB2 SBSPON FLRT3 FLRT1

1.07e-041965642b08cd6730119d5dea0152709ab8de580b66cd3c
ToppCellfacs-Aorta-Heart-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFB2 TGFB3 FLRT2 PLXNB2

1.07e-041965642029f58ce6a7b8c35d3a7496c3341391990909ce
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TGFB2 TGFB3 SBSPON WNT9A

1.10e-041975649d7a1c7dc70ba5e35645f19f9e056e4fa2494aa0
ToppCellFetal_29-31_weeks-Immune-alveolar_macrophage_(MARCO_positive)-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FGD2 AGRP GRN ITGB2

1.12e-04198564ab70bf89690410221ec7aa3149bb50ac34433f99
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_monocytic-non-classical_monocyte|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

FGD2 BRI3 GRN ITGB2

1.12e-04198564ecf1cb56bdd43b9c62cec3fcf914ede608a7c8a0
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TGFB2 TGFB3 WNT9A ITGB1

1.12e-04198564b258f672529fb2c03e62e2696d335043c4963280
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-Glial_immature|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TGFB2 LMO1 FLRT3 FLRT1

1.12e-04198564c8272ac4d90f2367f538f66db40de911ad73ea7f
ToppCellMonocytes|World / Immune cells in Kidney/Urine in Lupus Nephritis

FGD2 BRI3 GRN PLXNB2

1.12e-041985648beccf03c9ec9cd02a96107a9d7ca9a6764c6a61
ToppCellSevere_COVID-19-Myeloid-MoAM3|Severe_COVID-19 / Disease group,lineage and cell class (2021.01.30)

AGRP BRI3 GRN ITGB2

1.14e-0419956430523cf08815ca214877e33a2c52197ff8318557
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)-myeloid-myeloid_monocytic|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

FGD2 BRI3 GRN PLXNB2

1.14e-041995647dde5c02fcae64cd2d68f607500f2a46b97851fd
ToppCellBAL-Severe-Myeloid-MoAM-MoAM3|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

AGRP BRI3 GRN ITGB2

1.14e-04199564105709b97c55826a852aed27658e3b4af1738c8a
ToppCellTracheal-10x5prime-Stromal-Myofibroblastic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TGFB3 SBSPON HRC RYR2

1.14e-041995640a145172787f40d0fdaf21188d539ffaf7ece3e4
ToppCellCOVID-19-Myeloid-MoAM3,_VCAN|COVID-19 / Condition, Lineage and Cell class

AGRP BRI3 GRN ITGB2

1.14e-04199564aba0b833e44fe42625fac91466f6ebaa8e786d3b
ToppCellBAL-Severe-Myeloid-MoAM-MoAM3|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

AGRP BRI3 GRN ITGB2

1.14e-041995640892957a49304ce4b6daa3657d76d8365ce0dd19
ToppCellBAL-Severe-Myeloid-MoAM-MoAM3-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

AGRP BRI3 GRN ITGB2

1.14e-04199564b2dc3d0af6ecd3ab01779aaa1f061cb0f941cae8
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)-myeloid-myeloid_monocytic-monocyte|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

FGD2 BRI3 GRN PLXNB2

1.14e-0419956484879280851380e5bfe6bd48b6bbf57aedf6e003
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW23-Myeloid-Microglia|GW23 / Sample Type, Dataset, Time_group, and Cell type.

FGD2 GRN ITGB2 RYR1

1.14e-041995644ddfbcaa8054b69b3398d8c0d5fab8ae94805cb9
ToppCellBAL-Severe-Myeloid-MoAM-MoAM3-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

AGRP BRI3 GRN ITGB2

1.14e-04199564961ad44199871be8e09d31904d383edc865ba262
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AGRP BRI3 GRN ITGB2

1.14e-0419956481b3cb41abbee9785041170d0469edc50b622d7e
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TGFB2 LMO1 FLRT3 FLRT1

1.14e-041995648d13a9ea87f685b5a34b84c4571db6be753cf2d9
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c5-CD16|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

FGD2 BRI3 GRN PLXNB2

1.14e-04199564df946601b295be5419c09befbfa73f4314eef116
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.0.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AGRP BRI3 GRN ITGB2

1.14e-0419956453dac0455b84597460457ed429969a42ed0fe932
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AGRP BRI3 GRN ITGB2

1.14e-041995643216fdaba8be8e8e715aceb2c29f1ad5cc02f8ae
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW23-Myeloid|GW23 / Sample Type, Dataset, Time_group, and Cell type.

FGD2 GRN ITGB2 RYR1

1.14e-041995643ba48a4715d5e9387650aa97e0c5d7f7897bf380
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AGRP BRI3 GRN ITGB2

1.16e-042005644657d18e92abde7f0b8b7e4fc9fa0081efe20a55
ToppCellCOVID_vent-Myeloid|COVID_vent / Disease condition, Lineage, Cell class and subclass

BRI3 GRN PLXNB2 ITGB2

1.16e-04200564621af09aae34226902c03edf556562f3ab35a7d8
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Monocytic-Classical_Monocyte-Mono_c2-CD14-HLA-DPB1|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

BRI3 GRN PLXNB2 ITGB2

1.16e-0420056494679f6914dab1551ce1c58542a65c339254451d
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Myeloid-Monocytic-Classical_Monocyte-Mono_c2-CD14-HLA-DPB1|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

BRI3 GRN PLXNB2 ITGB2

1.16e-04200564b719af4e821f371459344693458bfd316cc2b37c
ToppCellCOVID_vent-Myeloid-Monocytic-CD14+_Monocyte|COVID_vent / Disease condition, Lineage, Cell class and subclass

BRI3 GRN PLXNB2 ITGB2

1.16e-04200564e57452b73abb21cb3f645d45523ab93f6bef0243
ToppCellCOVID_vent-Myeloid-Monocytic|COVID_vent / Disease condition, Lineage, Cell class and subclass

BRI3 GRN PLXNB2 ITGB2

1.16e-04200564b0a5bee87700ce38f26f95a6f491da7e27cade51
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AGRP BRI3 GRN ITGB2

1.16e-04200564f1255d4de08134bd0a95296c8cc743e90044d2ff
ToppCellCOVID_non-vent-Myeloid|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

BRI3 GRN PLXNB2 ITGB2

1.16e-04200564a40768e8e58c86b8e20bc188b9274ebe412fc765
ToppCellmild-Myeloid-CD14_Monocytes_1|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

FGD2 BRI3 GRN PLXNB2

1.16e-042005643874c1f078cb8789be2e2275a202357c711b1be3
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Myeloid-Monocytic-Classical_Monocyte|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

BRI3 GRN PLXNB2 ITGB2

1.16e-042005643408641b60c4cbc99da3f0cce7bf3d5247370f5f
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Myeloid|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

BRI3 GRN PLXNB2 ITGB2

1.16e-0420056411f6c597eca9c770d61a8cba83b26cde5fc7222d
ToppCellCOVID_non-vent-Myeloid-Monocytic|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

BRI3 GRN PLXNB2 ITGB2

1.16e-042005644243a9d32f3a11141284d0d944cb81194b532876
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Myeloid-Monocytic|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

BRI3 GRN PLXNB2 ITGB2

1.16e-042005641bf1be3461d8498454f1a064437bfbe2c0baa3ac
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Myeloid-Monocytic-Nonclassical_Monocyte|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

FGD2 BRI3 GRN PLXNB2

1.16e-0420056497f261d56bc6c55683eb4c42670d00b9a6992a26
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Rxfp1_Eya1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

LMO1 SBSPON OTOG

1.51e-048256342017b8ace6f142a8358213c95a2632226c3a867
ToppCellCOVID-19-Heart-Fib_+_CM|Heart / Disease (COVID-19 only), tissue and cell type

LMO3 SPPL2C RYR1

3.04e-041045630b60a56a46f1fe3f8224ec6399d009a34a117a21
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Neuronal-Interneuron|GW19 / Sample Type, Dataset, Time_group, and Cell type.

LMO1 FLRT1 RYR1

4.74e-04121563b2d571f571133c281d72584fe925cebbd2317829
ToppCellCOVID-19_Severe-Neu_3|World / 5 Neutrophil clusters in COVID-19 patients

TGFB2 LMO1 FLRT3

5.09e-0412456354b42ffb161eece4ae308782e43a0e0dc360281e
ToppCellHippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Nxph3|Hippocampus / BrainAtlas - Mouse McCarroll V32

WNT9A LMO3 SMYD3

6.95e-04138563b63e26afafbd2cdeed9c9451e6f530ab6295504c
ToppCellLymphoid-Lymphoid-NK_cells|Lymphoid / shred on cell class and cell subclass (v4)

ITGB1 ITGB2 SMYD3

8.51e-04148563d51a4b654a88d58dcdf29c2bc362c0cc1c40723a
ToppCelldroplet-Fat-Scat-21m-Myeloid-monocyte|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A5 ITGB2 RYR1

8.85e-04150563b6e5e04aaf1c5265ac07581868d3159f9292a84c
ToppCellLPS-antiTNF-Endothelial-Epi-like-Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

WNT9A LMO3 ZNHIT2

8.85e-041505639cb3332924bd67c966873343c14445e30d3f384f
ToppCellP15-Epithelial-epithelial_progenitor_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ADAMTS20 MUC5B FLRT1

9.19e-0415256300d5503d462cfa009fb4cac79ecee11725a18b9a
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Conventional_Leiomyosarcoma|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

LMO1 SBSPON RYR2

9.37e-04153563ec6fe6b8c884fa76adc7a0f9db041f7b1567a2ee
ComputationalT-cell proliferation genes.

VEGFC GRN CCKBR

1.45e-0436313MODULE_521
Drug2-nitrotoluene

TGFB2 TGFB3 ITGB1 ITGB2

1.54e-0561564ctd:C029955
Drug2-hydroxycarbazole

RYR1 RYR2

1.78e-053562CID000093551
Drugcis-diammineplatinum(II

RYR1 RYR2

1.78e-053562CID000159790
Drug2-hydroxyheptanoic acid

RYR1 RYR2

1.78e-053562CID002750949
DrugRyanodyl 3-(pyridine-3-carboxylate

RYR1 RYR2

1.78e-053562CID005748312
Drug8N3-cADPR

RYR1 RYR2

1.78e-053562CID000127713
Drugaminodantrolene

RYR1 RYR2

1.78e-053562CID009570289
DrugMW 1

VEGFC TGFB2 TGFB3 RYR1 RYR2

3.49e-05151565CID000073965
DrugPCB74

RYR1 RYR2

3.55e-054562CID000036218
Drug148504-47-6

RYR1 RYR2

3.55e-054562CID006444275
DrugSC 38249

RYR1 RYR2

3.55e-054562CID000134834
DrugAC1L1U7A

RYR1 RYR2

3.55e-054562CID000035682
DrugAC1O3MMZ

TGFB2 TGFB3

3.55e-054562CID006332294
Drug2-(2,6-dioxopiperidin-3-yl)phthalimidine

ITGB1 ITGB2

5.91e-055562ctd:C001079
DrugChlorthalidone

VEGFC TGFB3

5.91e-055562ctd:D002752
DrugA 68930

RYR1 RYR2

5.91e-055562ctd:C065380
Drugtrichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A

VEGFC TGFB3 CTCF SUV39H1 ZNHIT2

8.05e-051805656886_DN
DrugMBED

RYR1 RYR2

8.86e-056562CID000129958
Drugchloro-m-cresol

RYR1 RYR2

8.86e-056562CID000012008
DrugAC1O528X

RYR1 RYR2

8.86e-056562CID006475857
DrugNSC114784

RYR1 RYR2

8.86e-056562CID000419425
DrugAzacytidine-5 [320-67-2]; Up 200; 16.4uM; MCF7; HT_HG-U133A

TGFB2 AGRP MUC5B FLRT3 CCKBR

1.12e-041935653348_UP
DrugAzumoleno

RYR1 RYR2

1.24e-047562CID000056259
DrugBr2BAPTA

RYR1 RYR2

1.24e-047562CID003081001
Drug[[(2R,3S,4R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-3,4,5-trihydroxyoxolan-2-yl]methyl hydrogen phosphate

RYR1 RYR2

1.24e-047562CID009547999
Drug1d3q

TGFB2 TGFB3 CCKBR

1.31e-0440563CID000001635
Drugbromochloroacetic acid

TGFB2 TGFB3 ITGB1 ITGB2

1.51e-04109564ctd:C099813
Diseaseosteochondrodysplasia (biomarker_via_orthology)

TGFB2 RYR1

3.41e-062552DOID:2256 (biomarker_via_orthology)
Diseasecongenital myopathy 1A (implicated_via_orthology)

RYR1 RYR2

1.02e-053552DOID:3529 (implicated_via_orthology)
DiseaseCongenital abnormality of respiratory system

TGFB2 TGFB3

1.02e-053552C0035238
Diseasemalignant hyperthermia (implicated_via_orthology)

RYR1 RYR2

1.02e-053552DOID:8545 (implicated_via_orthology)
DiseaseLoeys-Dietz Aortic Aneurysm Syndrome

TGFB2 TGFB3

3.40e-055552C1836635
DiseaseLoeys-Dietz Syndrome, Type 1a

TGFB2 TGFB3

3.40e-055552C4551955
DiseaseLoeys-Dietz Syndrome

TGFB2 TGFB3

7.12e-057552C2697932
Diseasepancreatic cancer (biomarker_via_orthology)

EZH2 CCKBR

7.12e-057552DOID:1793 (biomarker_via_orthology)
DiseaseLeukemia, Megakaryoblastic, of Down Syndrome

CTCF EZH2

9.48e-058552C1860789
Diseasearrhythmogenic right ventricular cardiomyopathy (is_implicated_in)

TGFB3 RYR2

1.52e-0410552DOID:0050431 (is_implicated_in)
DiseaseCognitive impairment

SMYD3 RYR2

1.86e-0411552HP_0100543
DiseaseChromosome Breaks

SUV39H1 EZH2

3.06e-0414552C0333704
DiseaseChromosome Breakage

SUV39H1 EZH2

3.06e-0414552C0376628
DiseasePulmonary Emphysema

TGFB2 TGFB3

4.56e-0417552C0034067
Diseasediabetic neuropathy (biomarker_via_orthology)

TGFB2 TGFB3

4.56e-0417552DOID:9743 (biomarker_via_orthology)
Diseaseselenium measurement, response to dietary selenium supplementation

LMO1 GPR156

6.34e-0420552EFO_0006331, EFO_0600021
Diseasepancreatic ductal adenocarcinoma (is_marker_for)

TGFB2 TGFB3

1.16e-0327552DOID:3498 (is_marker_for)
Diseasecongestive heart failure (is_implicated_in)

EZH2 RYR1

1.16e-0327552DOID:6000 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
CCDPCATCYCRFFNA

AGRP

101

O00253
GERPFQCCQCSYASR

CTCFL

366

Q8NI51
FQCELCSYTCPRRSN

CTCF

266

P49711
LICGNPDCTRCYCFE

DNMT3L

106

Q9UJW3
FICCFALRKRRCPNC

BRI3

106

O95415
DCRLYCDPEACACSQ

CSRNP2

216

Q9H175
WACCPYRQGVCCADR

GRN

541

P28799
CPSVCRCDAGFIYCN

FLRT3

31

Q9NZU0
RLRYSVCCKVCPNFC

CD300LD-AS1

116

Q96MU5
RVQCNRCNEVFCFKC

ARIH2

246

O95376
RFRQACLETCARCCP

CCKBR

396

P32239
DCPNCNYRRRCACDD

FAM193A

201

P78312
CPSVCRCDRNFVYCN

FLRT2

36

O43155
YQCPFNGSRREDCEC

ADAMTS20

1776

P59510
ACCDPCASCQCRFFR

ASIP

106

P42127
DCCPTFRCRPQLCSY

MUC5B

5511

Q9HC84
CRVCECNPNYTGSAC

ITGB1

576

P05556
LDCFACQLCNQRFCV

LMO1

111

P25800
CRCACFCTDNLYVAR

OGFOD2

11

Q6N063
CDNCYQQQDNLCPFC

KMT2C

456

Q8NEZ4
YHPGCFRCVICNECL

LIMD1

556

Q9UGP4
FCQCSSECQNRFPGC

EZH2

546

Q15910
DCSLCRAANPDYRCA

PLXNB2

766

O15031
DCFACQLCNQRFCVG

LMO3

101

Q8TAP4
CRGQRCPCYSNRKAC

MSL2

476

Q9HCI7
RSQHICCYECQNCPE

GPRC6A

536

Q5T6X5
CRCNVCECHSGYQLP

ITGB2

596

P05107
CYRVYCCCCLANVSL

DENND11

271

A4D1U4
RRCALCYDKCFPNAC

COL6A5

1936

A8TX70
CRACGYVVCARCSDY

FGD2

481

Q7Z6J4
CRCHRPYCEICFQSS

GPR156

756

Q8NFN8
CPSVCRCDNGFIYCN

FLRT1

26

Q9NZU1
QCCFCSCINDVPPQY

SEC24C

446

P53992
SCCRFLCYFCRISRQ

RYR1

2231

P21817
CCRFLCYFCRISRQN

RYR2

2196

Q92736
TELCCPLYQCVCENF

OTOG

2601

Q6ZRI0
NCTCFPCPYKDERNC

TRIM42

36

Q8IWZ5
PCPYKDERNCQFCHC

TRIM42

41

Q8IWZ5
VAYCCRFDVQVCSRQ

SPPL2C

456

Q8IUH8
CSQCNTNFCYRCGER

RNF217

441

Q8TC41
LCGYCSFCNRCTECE

HRC

626

P23327
QYCFECDCFRCQTQD

SMYD3

256

Q9H7B4
ECNSRCRCGYDCPNR

SUV39H1

221

O43463
AAYCFRNVQDNCCLR

TGFB2

306

P61812
PLTRKCCYRACFRQC

WFDC5

56

Q8TCV5
CCYRACFRQCVPRVS

WFDC5

61

Q8TCV5
CSCYRRPCTNRQKAC

VEGFC

381

P49767
AARCVCPFCQRELYE

RNF125

136

Q96EQ8
CRFTGDCCFDYDRAC

SBSPON

56

Q8IVN8
DCCFDYDRACPARPC

SBSPON

61

Q8IVN8
CCFPTFLNARACACA

RP1L1

1256

Q8IWN7
EGQRCHRFACNTCPY

POLR3K

16

Q9Y2Y1
CQCCDCGRVFSRNSY

ZIM2

466

Q9NZV7
TCPRCNAPYCSLRCY

ZNHIT2

21

Q9UHR6
TRPCQCQVRWCCYVE

WNT9A

336

O14904
CRFNTQCTRPDCTFY

ZC3H14

701

Q6PJT7
RCPACRVPYCSVVCF

ZNHIT3

21

Q15649
CRENPARVCDQCYSY

ZFYVE26

1856

Q68DK2
YCFRNLEENCCVRPL

TGFB3

306

P10600