Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionphospholipid binding

TNFAIP8L3 DOK7 SPTBN1 MYO1B PICALM PXK CADPS CIBAR1 SBF2 ARHGAP44 RACGAP1 AKT1 PRKCI

2.18e-0554811813GO:0005543
GeneOntologyMolecularFunctionhistone deacetylase binding

MAGEA11 MEF2B SRF MEF2A MEF2C MEF2D TBX2

2.71e-051471187GO:0042826
GeneOntologyMolecularFunctionglucosamine-6-phosphate deaminase activity

GNPDA1 GNPDA2

3.46e-0521182GO:0004342
GeneOntologyMolecularFunctiondeaminase activity

ADAD1 GNPDA1 GNPDA2 CDADC1

4.69e-05341184GO:0019239
GeneOntologyMolecularFunctionphosphatidylinositol binding

TNFAIP8L3 DOK7 MYO1B PICALM PXK CADPS SBF2 RACGAP1 AKT1

1.10e-043161189GO:0035091
GeneOntologyMolecularFunctioncalmodulin binding

MYO1A SPTBN1 MYO1B RYR2 ASPM AKT1 SNTB1

4.38e-042301187GO:0005516
GeneOntologyMolecularFunctionprotein dimerization activity

ANO2 SUPT3H MEF2B FMR1 MYOM3 SRF XPA IDE CHKA MEF2A PTGS2 MEF2C MEF2D FZD9 CLCN1 CDADC1 AKT1

7.16e-04120511817GO:0046983
GeneOntologyMolecularFunctionlipid binding

TNFAIP8L3 TEX2 DOK7 SPTBN1 MYO1B NR3C1 PICALM PXK CADPS CIBAR1 SBF2 ARHGAP44 RACGAP1 AKT1 PRKCI

7.20e-0498811815GO:0008289
GeneOntologyBiologicalProcessregulation of protein localization to membrane

VPS26B DOK7 SPTBN1 IQSEC2 PICALM FZD9 ARHGAP44 AKT1 PRKCI EFCAB7

1.01e-0623711710GO:1905475
GeneOntologyBiologicalProcessregulation of protein localization to cell periphery

VPS26B SPTBN1 IQSEC2 PICALM ARHGAP44 AKT1 PRKCI EFCAB7

6.00e-061711178GO:1904375
GeneOntologyBiologicalProcessmuscle cell fate determination

MEF2C TBX2

3.19e-0521172GO:0007521
GeneOntologyBiologicalProcessglucosamine catabolic process

GNPDA1 GNPDA2

3.19e-0521172GO:0006043
GeneOntologyBiologicalProcessUV-damage excision repair

CUL4B XPA XPC

6.19e-05141173GO:0070914
GeneOntologyBiologicalProcessamyloid-beta clearance

SRF IDE PICALM IL4

7.68e-05401174GO:0097242
GeneOntologyBiologicalProcessmembraneless organelle assembly

KNTC1 FMR1 NEBL MYOM3 SRF MEF2A MEF2C MDN1 ASPM RACGAP1 MRTO4

8.32e-0547511711GO:0140694
GeneOntologyBiologicalProcessnegative regulation of synaptic transmission

FMR1 IQSEC2 SRF GRIK1 PTGS2

9.23e-05801175GO:0050805
GeneOntologyBiologicalProcessembryonic heart tube morphogenesis

TBX3 SRF MEF2C RYR2 TBX2

9.23e-05801175GO:0003143
GeneOntologyBiologicalProcessureteric peristalsis

TBX3 TBX2

9.54e-0531172GO:0072105
GeneOntologyBiologicalProcessureter smooth muscle contraction

TBX3 TBX2

9.54e-0531172GO:0014849
GeneOntologyBiologicalProcessN-acetylglucosamine catabolic process

GNPDA1 GNPDA2

9.54e-0531172GO:0006046
GeneOntologyBiologicalProcesssynaptic transmission, glutamatergic

IQSEC2 GRIK1 VPS54 NR3C1 PTGS2 MEF2C

1.07e-041321176GO:0035249
GeneOntologyBiologicalProcessnegative regulation of plasma membrane bounded cell projection assembly

MAK RAB3IP ARHGAP44 AKT1

1.22e-04451174GO:0120033
GeneOntologyBiologicalProcessmyofibril assembly

NEBL MYOM3 SRF MEF2A MEF2C

1.30e-04861175GO:0030239
GeneOntologyBiologicalProcessmuscle cell fate commitment

TBX3 MEF2C TBX2

1.36e-04181173GO:0042693
GeneOntologyBiologicalProcessstriated muscle cell development

NEBL MYOM3 SRF MEF2A MEF2C

1.53e-04891175GO:0055002
GeneOntologyBiologicalProcessmammary placode formation

TBX3 TBX2

1.90e-0441172GO:0060596
GeneOntologyBiologicalProcesscardiac myofibril assembly

NEBL SRF MEF2A

2.20e-04211173GO:0055003
GeneOntologyBiologicalProcessanterograde trans-synaptic signaling

GABRB2 FMR1 IQSEC2 SRF GRIK1 VPS54 NR3C1 PTGS2 MEF2C PXK UBE3A CADPS ARHGAP44 PRKAR2A AKT1

2.51e-0493111715GO:0098916
GeneOntologyBiologicalProcesschemical synaptic transmission

GABRB2 FMR1 IQSEC2 SRF GRIK1 VPS54 NR3C1 PTGS2 MEF2C PXK UBE3A CADPS ARHGAP44 PRKAR2A AKT1

2.51e-0493111715GO:0007268
GeneOntologyBiologicalProcessregulation of synaptic plasticity

FMR1 IQSEC2 SRF GRIK1 NR3C1 PTGS2 MEF2C UBE3A

2.70e-042931178GO:0048167
GeneOntologyBiologicalProcesscardiocyte differentiation

TBX3 NEBL SRF NR3C1 MEF2A MEF2C TBX2

2.70e-042211177GO:0035051
GeneOntologyBiologicalProcesstrans-synaptic signaling

GABRB2 FMR1 IQSEC2 SRF GRIK1 VPS54 NR3C1 PTGS2 MEF2C PXK UBE3A CADPS ARHGAP44 PRKAR2A AKT1

2.75e-0493911715GO:0099537
GeneOntologyBiologicalProcessmuscle system process

TBX3 SRF VPS54 NR3C1 MEF2A PTGS2 MEF2C RYR2 CLCN1 SNTB1 TBX2

2.84e-0454711711GO:0003012
GeneOntologyBiologicalProcessembryonic heart tube development

TBX3 SRF MEF2C RYR2 TBX2

3.03e-041031175GO:0035050
GeneOntologyBiologicalProcessregulation of filopodium assembly

FMR1 SRF RAB3IP ARHGAP44

3.08e-04571174GO:0051489
GeneOntologyBiologicalProcessatrioventricular canal morphogenesis

TBX3 TBX2

3.15e-0451172GO:1905222
GeneOntologyBiologicalProcessregulation of cellular respiration

TMEM135 IDE AKT1 IL4

3.29e-04581174GO:0043457
GeneOntologyBiologicalProcessmuscle structure development

TBX3 MEF2B NEBL MYOM3 SRF VPS54 NR3C1 MEF2A MEF2C MEF2D RYR2 AKT1 IL4 TBX2

3.61e-0485811714GO:0061061
GeneOntologyBiologicalProcessstriated muscle cell differentiation

TBX3 NEBL MYOM3 SRF NR3C1 MEF2A MEF2C AKT1 IL4

3.93e-043911179GO:0051146
GeneOntologyBiologicalProcesssynaptic signaling

GABRB2 FMR1 IQSEC2 SRF GRIK1 VPS54 NR3C1 PTGS2 MEF2C PXK UBE3A CADPS ARHGAP44 PRKAR2A AKT1

4.14e-0497611715GO:0099536
GeneOntologyBiologicalProcesscardiac jelly development

TBX3 TBX2

4.71e-0461172GO:1905072
GeneOntologyBiologicalProcessnegative regulation of filopodium assembly

RAB3IP ARHGAP44

4.71e-0461172GO:0051490
GeneOntologyBiologicalProcessglucosamine metabolic process

GNPDA1 GNPDA2

4.71e-0461172GO:0006041
GeneOntologyBiologicalProcesscardiac muscle cell differentiation

TBX3 NEBL SRF NR3C1 MEF2A MEF2C

5.22e-041771176GO:0055007
GeneOntologyBiologicalProcesscardiac muscle tissue development

TBX3 NEBL SRF NR3C1 MEF2A MEF2C RYR2 TBX2

5.59e-043271178GO:0048738
GeneOntologyCellularComponentglutamatergic synapse

GABRB2 ANO2 FMR1 VPS26B SPTB SPTBN1 IQSEC2 GRIK1 NR3C1 FZD9 UBE3A CADPS ARHGAP44 PRKAR2A AKT1 PRKCI

1.60e-0581711916GO:0098978
GeneOntologyCellularComponentpostsynapse

GABRB2 RPL37A FMR1 VPS26B DOK7 SPTB SPTBN1 IQSEC2 RPS9 RPS10 GRIK1 NR3C1 PICALM MEF2C FZD9 UBE3A ARHGAP44 AKT1

1.79e-05101811918GO:0098794
GeneOntologyCellularComponentnucleotide-excision repair complex

XPA XPC XRCC4

4.93e-05131193GO:0000109
HumanPhenoObesity

CUL4B TBX3 MAK FMR1 SPTBN1 IQSEC2 NR3C1 XRCC4 MEF2A PNPLA6 UBE3A SDC3 AKT1 SNRNP200

1.68e-054254714HP:0001513
DomainMADS_BOX_1

MEF2B SRF MEF2A MEF2C MEF2D

5.52e-1161185PS00350
DomainMADS

MEF2B SRF MEF2A MEF2C MEF2D

5.52e-1161185SM00432
DomainSRF-TF

MEF2B SRF MEF2A MEF2C MEF2D

5.52e-1161185PF00319
DomainMADS_BOX_2

MEF2B SRF MEF2A MEF2C MEF2D

5.52e-1161185PS50066
DomainTF_MADSbox

MEF2B SRF MEF2A MEF2C MEF2D

1.92e-1071185IPR002100
DomainMADS_MEF2-like

MEF2B MEF2A MEF2C MEF2D

1.51e-0941184IPR033896
DomainHJURP_C

MEF2A MEF2C MEF2D

9.79e-0741183IPR022102
DomainHJURP_C

MEF2A MEF2C MEF2D

9.79e-0741183PF12347
DomainTBX

TBX3 TBX2

3.96e-0521182IPR022582
DomainGlucosamine6P_isomerase_CS

GNPDA1 GNPDA2

3.96e-0521182IPR018321
DomainTBX

TBX3 TBX2

3.96e-0521182PF12598
DomainGlucosamine6P_isomerase

GNPDA1 GNPDA2

3.96e-0521182IPR004547
DomainGLC_GALNAC_ISOMERASE

GNPDA1 GNPDA2

3.96e-0521182PS01161
DomainPH

TEX2 DOK7 SPTBN1 IQSEC2 SBF1 CADPS SBF2 AKT1 SNTB1

6.84e-052781189SM00233
DomainPH_domain

TEX2 DOK7 SPTBN1 IQSEC2 SBF1 CADPS SBF2 AKT1 SNTB1

7.23e-052801189IPR001849
DomainSBF2

SBF1 SBF2

1.18e-0431182PF12335
DomainSBF1/SBF2

SBF1 SBF2

1.18e-0431182IPR022096
DomainSpectrin_bsu

SPTB SPTBN1

2.36e-0441182IPR016343
DomainGlc/Gal-6P_isomerase

GNPDA1 GNPDA2

2.36e-0441182IPR006148
DomainGlucosamine_iso

GNPDA1 GNPDA2

2.36e-0441182PF01182
DomainPH_DOMAIN

DOK7 SPTBN1 IQSEC2 SBF1 CADPS SBF2 AKT1 SNTB1

3.97e-042791188PS50003
DomainMyosin_TH1

MYO1A MYO1B

8.14e-0471182PF06017
DomainMyosin_TH1

MYO1A MYO1B

8.14e-0471182IPR010926
DomainTH1

MYO1A MYO1B

8.14e-0471182PS51757
DomainIQ

MYO1A IQSEC2 MYO1B ASPM

1.06e-03711184PF00612
DomainCNMP_BINDING_1

CNBD1 PNPLA6 PRKAR2A

1.07e-03321183PS00888
DomainCNMP_BINDING_2

CNBD1 PNPLA6 PRKAR2A

1.07e-03321183PS00889
DomaincNMP_binding

CNBD1 PNPLA6 PRKAR2A

1.28e-03341183PF00027
DomaincNMP-bd_dom

CNBD1 PNPLA6 PRKAR2A

1.39e-03351183IPR000595
DomainCNMP_BINDING_3

CNBD1 PNPLA6 PRKAR2A

1.39e-03351183PS50042
DomainPH_dom-like

DOK7 SPTBN1 IQSEC2 MYO1B SBF1 CADPS SBF2 AKT1 SNTB1

1.54e-034261189IPR011993
DomaincNMP-bd-like

CNBD1 PNPLA6 PRKAR2A

1.77e-03381183IPR018490
DomainIQ_motif_EF-hand-BS

MYO1A IQSEC2 MYO1B ASPM

2.55e-03901184IPR000048
DomainIQ

MYO1A IQSEC2 MYO1B ASPM

2.87e-03931184PS50096
DomainPH

SPTBN1 SBF1 CADPS SBF2 AKT1 SNTB1

3.35e-032291186PF00169
Domain-

DOK7 SPTBN1 IQSEC2 SBF1 CADPS SBF2 AKT1 SNTB1

3.40e-0339111882.30.29.30
DomainMyotubularin-like_Pase_dom

SBF1 SBF2

3.43e-03141182IPR010569
DomainuDENN

SBF1 SBF2

3.43e-03141182SM00800
DomainPPASE_MYOTUBULARIN

SBF1 SBF2

3.43e-03141182PS51339
DomainMyotubularin_fam

SBF1 SBF2

3.43e-03141182IPR030564
DomainMyotub-related

SBF1 SBF2

3.43e-03141182PF06602
Domain-

CNBD1 PNPLA6 PRKAR2A

3.46e-034811832.60.120.10
DomainuDENN

SBF1 SBF2

3.94e-03151182PF03456
DomainRmlC-like_jellyroll

CNBD1 PNPLA6 PRKAR2A

4.11e-03511183IPR014710
DomainGRAM

SBF1 SBF2

4.48e-03161182SM00568
DomainDENN

SBF1 SBF2

4.48e-03161182SM00799
DomainDENN

SBF1 SBF2

4.48e-03161182PF02141
DomaindDENN

SBF1 SBF2

4.48e-03161182PF03455
DomainUDENN

SBF1 SBF2

4.48e-03161182PS50946
DomainDDENN

SBF1 SBF2

4.48e-03161182PS50947
DomaindDENN

SBF1 SBF2

4.48e-03161182SM00801
DomaindDENN_dom

SBF1 SBF2

4.48e-03161182IPR005112
DomainuDENN_dom

SBF1 SBF2

4.48e-03161182IPR005113
DomainDENN

SBF1 SBF2

4.48e-03161182PS50211
DomainDENN_dom

SBF1 SBF2

4.48e-03161182IPR001194
DomainTF_T-box

TBX3 TBX2

5.06e-03171182IPR001699
DomainTBOX

TBX3 TBX2

5.06e-03171182SM00425
DomainTF_T-box_CS

TBX3 TBX2

5.06e-03171182IPR018186
Domain-

TBX3 TBX2

5.06e-031711822.60.40.820
DomainTBOX_3

TBX3 TBX2

5.06e-03171182PS50252
DomainT-box

TBX3 TBX2

5.06e-03171182PF00907
DomainTBOX_1

TBX3 TBX2

5.06e-03171182PS01283
DomainTBOX_2

TBX3 TBX2

5.06e-03171182PS01264
PathwayWP_SRF_AND_MIRS_IN_SMOOTH_MUSCLE_DIFFERENTIATION_AND_PROLIFERATION

MEF2B SRF MEF2A MEF2C MEF2D

6.41e-0818875M39393
PathwayWP_CELL_DIFFERENTIATION_INDEX

MEF2B SRF MEF2A MEF2C MEF2D

1.36e-0550875M39528
PathwayREACTOME_MYOGENESIS

MEF2B MEF2A MEF2C MEF2D

2.86e-0529874M853
PathwayWP_CELL_DIFFERENTIATION_EXPANDED_INDEX

MEF2B SRF MEF2A MEF2C MEF2D

3.07e-0559875M39723
Pubmed

Regional chromosomal assignments for four members of the MADS domain transcription enhancer factor 2 (MEF2) gene family to human chromosomes 15q26, 19p12, 5q14, and 1q12-q23.

MEF2B MEF2A MEF2C MEF2D

1.30e-10411948575763
Pubmed

Transcriptional activity of MEF2 during mouse embryogenesis monitored with a MEF2-dependent transgene.

MEF2B MEF2A MEF2C MEF2D

1.30e-104119410207130
Pubmed

Spine growth in the anterior cingulate cortex is necessary for the consolidation of contextual fear memory.

MEF2B MEF2A MEF2C MEF2D

1.30e-104119421531906
Pubmed

MEF2 transcription factors regulate distinct gene programs in mammalian skeletal muscle differentiation.

MEF2B MEF2A MEF2C MEF2D

1.30e-104119425416778
Pubmed

Neurotoxin-induced selective ubiquitination and regulation of MEF2A isoform in neuronal stress response.

MEF2B MEF2A MEF2C MEF2D

1.30e-104119422764880
Pubmed

Expression of mef2 genes in the mouse central nervous system suggests a role in neuronal maturation.

MEF2B MEF2A MEF2C MEF2D

1.30e-10411947643214
Pubmed

FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.

CUL4B RPL37A FMR1 RPS9 RPS10 ABCF2 MYO1B SUCLG1 IGF2BP2 PNPLA6 SUB1 SBF2 SMARCA1 PYGL MRTO4 SNRNP200

2.70e-106011191633658012
Pubmed

The MEF2B homologue differentially expressed in mouse embryonal carcinoma cells.

MEF2B MEF2A MEF2C MEF2D

6.50e-10511947646512
Pubmed

Galpha13 regulates MEF2-dependent gene transcription in endothelial cells: role in angiogenesis.

MEF2B MEF2A MEF2C MEF2D

6.50e-105119419093215
Pubmed

Regulatory role of MEF2D in serum induction of the c-jun promoter.

MEF2B MEF2A MEF2C MEF2D

6.50e-10511947760790
Pubmed

Absence of MEF2 binding to the A/T-rich element in the muscle creatine kinase (MCK) enhancer correlates with lack of early expression of the MCK gene in embryonic mammalian muscle.

MEF2B MEF2A MEF2C MEF2D

6.50e-10511948993831
Pubmed

Calcineurin initiates skeletal muscle differentiation by activating MEF2 and MyoD.

MEF2B MEF2A MEF2C MEF2D

6.50e-105119412694204
Pubmed

Expression of MEF2 genes during human cardiac development.

MEF2B MEF2A MEF2C MEF2D

6.50e-105119410458488
Pubmed

Postsynaptic FMRP bidirectionally regulates excitatory synapses as a function of developmental age and MEF2 activity.

FMR1 MEF2A MEF2C MEF2D

6.50e-105119423511190
Pubmed

Influence of natriuretic peptide receptor-1 on survival and cardiac hypertrophy during development.

SRF MEF2A MEF2C MEF2D AKT1

1.26e-0915119519782130
Pubmed

The expression of MEF2 genes is implicated in CNS neuronal differentiation.

MEF2B MEF2A MEF2C MEF2D

1.94e-09611949013788
Pubmed

MEF2B Instructs Germinal Center Development and Acts as an Oncogene in B Cell Lymphomagenesis.

MEF2B MEF2A MEF2C MEF2D

9.02e-098119430205047
Pubmed

Myocyte Enhancer Factor 2c Regulates Dendritic Complexity and Connectivity of Cerebellar Purkinje Cells.

MEF2B MEF2A MEF2C MEF2D

2.69e-0810119430276662
Pubmed

In vivo analysis of MEF2 transcription factors in synapse regulation and neuronal survival.

MEF2A MEF2C MEF2D

3.91e-083119322496871
Pubmed

Myocyte enhancer factor-2 and serum response factor binding elements regulate fast Myosin heavy chain transcription in vivo.

MEF2B SRF MEF2A

3.91e-083119315728583
Pubmed

Alternative pre-mRNA splicing governs expression of a conserved acidic transactivation domain in myocyte enhancer factor 2 factors of striated muscle and brain.

MEF2A MEF2C MEF2D

3.91e-083119315834131
Pubmed

An intragenic MEF2-dependent enhancer directs muscle-specific expression of microRNAs 1 and 133.

MEF2A MEF2C MEF2D

3.91e-083119318093911
Pubmed

Experience-Dependent and Differential Regulation of Local and Long-Range Excitatory Neocortical Circuits by Postsynaptic Mef2c.

MEF2A MEF2C MEF2D

3.91e-083119327989458
Pubmed

Inducible knockout of Mef2a, -c, and -d from nestin-expressing stem/progenitor cells and their progeny unexpectedly uncouples neurogenesis and dendritogenesis in vivo.

MEF2A MEF2C MEF2D

3.91e-083119326286136
Pubmed

MEF2 transcription factors differentially contribute to retinal ganglion cell loss after optic nerve injury.

MEF2A MEF2C MEF2D

3.91e-083119333315889
Pubmed

Control of mouse cardiac morphogenesis and myogenesis by transcription factor MEF2C.

MEF2B MEF2A MEF2C MEF2D

4.22e-081111949162005
Pubmed

Enhanced Functional Genomic Screening Identifies Novel Mediators of Dual Leucine Zipper Kinase-Dependent Injury Signaling in Neurons.

MEF2A MEF2C MEF2D MAP2K7

6.31e-0812119428641113
Pubmed

RNA microarray analysis in prenatal mouse cochlea reveals novel IGF-I target genes: implication of MEF2 and FOXM1 transcription factors.

MEF2B MEF2A MEF2C MEF2D AKT1

8.06e-0832119520111592
Pubmed

Cyclin D-cdk4 activity modulates the subnuclear localization and interaction of MEF2 with SRC-family coactivators during skeletal muscle differentiation.

MEF2B MEF2A MEF2C MEF2D

1.27e-0714119412130539
Pubmed

TEF-1 and MEF2 transcription factors interact to regulate muscle-specific promoters.

SRF MEF2A MEF2C

1.56e-074119312061776
Pubmed

Neuronal Myocyte-Specific Enhancer Factor 2D (MEF2D) Is Required for Normal Circadian and Sleep Behavior in Mice.

MEF2A MEF2C MEF2D

1.56e-074119331420455
Pubmed

Early expression of the different isoforms of the myocyte enhancer factor-2 (MEF2) protein in myogenic as well as non-myogenic cell lineages during mouse embryogenesis.

MEF2A MEF2C MEF2D

1.56e-07411938817457
Pubmed

Requirement of MEF2A, C, and D for skeletal muscle regeneration.

MEF2A MEF2C MEF2D

1.56e-074119324591619
Pubmed

MEF2C transcription factor controls chondrocyte hypertrophy and bone development.

MEF2B MEF2A MEF2C MEF2D

3.00e-0717119417336904
Pubmed

Control of the SOST bone enhancer by PTH using MEF2 transcription factors.

MEF2A MEF2C MEF2D

3.89e-075119317696759
Pubmed

Membrane hyperpolarization triggers myogenin and myocyte enhancer factor-2 expression during human myoblast differentiation.

MEF2B MEF2A MEF2C

3.89e-075119315084602
Pubmed

Histone demethylase LSD1 is required to induce skeletal muscle differentiation by regulating myogenic factors.

MEF2A MEF2C MEF2D

3.89e-075119320833138
Pubmed

MEF2 transcription factors are key regulators of sprouting angiogenesis.

MEF2A MEF2C MEF2D

3.89e-075119327898394
Pubmed

Interaction of myocyte enhancer factor 2 (MEF2) with a mitogen-activated protein kinase, ERK5/BMK1.

MEF2A MEF2C MEF2D

3.89e-07511939753748
Pubmed

Regulation of the MEF2 family of transcription factors by p38.

MEF2A MEF2C MEF2D

3.89e-07511939858528
Pubmed

Cooperative transcriptional activation by the neurogenic basic helix-loop-helix protein MASH1 and members of the myocyte enhancer factor-2 (MEF2) family.

MEF2A MEF2C MEF2D

3.89e-07511938900141
Pubmed

Cooperation between MEF2 and PPARgamma in human intestinal beta,beta-carotene 15,15'-monooxygenase gene expression.

MEF2B MEF2A MEF2C

3.89e-075119316504037
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

CDK17 RPL37A TEX2 SPTBN1 RPS10 POR NR3C1 NCBP3 MDN1 PNPLA6 SBF1 ASPM PRKAR2A PRKCI MRTO4 SNRNP200 GPAT4 MRPL1 SNTB1

7.28e-0714871191933957083
Pubmed

Akt binds prohibitin 2 and relieves its repression of MyoD and muscle differentiation.

MEF2A MEF2C AKT1

7.75e-076119315173318
Pubmed

TRIM72, a novel negative feedback regulator of myogenesis, is transcriptionally activated by the synergism of MyoD (or myogenin) and MEF2.

MEF2A MEF2C MEF2D

7.75e-076119320399744
Pubmed

Signal-dependent activation of the MEF2 transcription factor by dissociation from histone deacetylases.

MEF2A MEF2C MEF2D

7.75e-076119310737771
Pubmed

Transcription enhancer factor 1 binds multiple muscle MEF2 and A/T-rich elements during fast-to-slow skeletal muscle fiber type transitions.

MEF2B MEF2A MEF2C

1.35e-067119312861002
Pubmed

Mef2 gene expression marks the cardiac and skeletal muscle lineages during mouse embryogenesis.

MEF2A MEF2C MEF2D

1.35e-06711938026334
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

CUL4B TBX3 SUPT3H FMR1 XPC SUCLG1 SLC35G1 IGF2BP2 PNPLA6 SAT1 CADPS CIBAR1 ASPM SMARCA1 MAP2K7 TBX2

1.38e-0611161191631753913
Pubmed

MEF2-dependent recruitment of the HAND1 transcription factor results in synergistic activation of target promoters.

MEF2A MEF2C MEF2D

2.16e-068119316043483
Pubmed

Histone deacetylase 3 interacts with and deacetylates myocyte enhancer factor 2.

MEF2B SRF MEF2D

2.16e-068119317158926
Pubmed

Histone deacetylase degradation and MEF2 activation promote the formation of slow-twitch myofibers.

MEF2A MEF2C MEF2D

2.16e-068119317786239
Pubmed

Combinatorial cis-acting elements control tissue-specific activation of the cardiac troponin I gene in vitro and in vivo.

MEF2A MEF2C MEF2D

3.23e-06911939738004
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

SPTBN1 RPS9 RPS10 ABCF2 MYO1B XPC IGF2BP2 MDN1 PNPLA6 SBF1 UBE3A ASPM SMARCA1 RACGAP1 PYGL MRTO4 SNRNP200

3.72e-0613531191729467282
Pubmed

Genetic analysis of specific and redundant roles for p38alpha and p38beta MAPKs during mouse development.

MEF2B MEF2A MEF2C MEF2D

4.35e-0632119421768366
Pubmed

Mef2d is essential for the maturation and integrity of retinal photoreceptor and bipolar cells.

MEF2B MEF2A MEF2C MEF2D

4.35e-0632119425757744
Pubmed

The Rho guanine nucleotide exchange factor AKAP13 (BRX) is essential for cardiac development in mice.

SRF MEF2C TBX2

6.32e-0611119320139090
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

RPL37A FMR1 RPS9 RPS10 ABCF2 MYO1B XPC IGF2BP2 MDN1 PNPLA6 RACGAP1 MRTO4 SNRNP200

7.04e-068471191335850772
Pubmed

High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men.

SOX5 TBX3 IDE NR3C1 MEF2A MEF2C MEF2D AKT1 TBX2

7.23e-06383119919453261
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

KNTC1 RPL37A FMR1 SPTBN1 RPS9 RPS10 POR ABCF2 MYO1B IDE MDN1 SMARCA1 RACGAP1 PRKAR2A PRKCI MRTO4 SNRNP200

7.36e-0614251191730948266
Pubmed

CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.

FMR1 SPTBN1 RPS9 RPS10 MYO1B NCBP3 IGF2BP2 MDN1 SMARCA1 MRTO4 SNRNP200

7.80e-066051191128977666
Pubmed

Skeletal muscle specification by myogenin and Mef2D via the SWI/SNF ATPase Brg1.

MEF2A MEF2C MEF2D

8.40e-0612119316424906
Pubmed

Coordinated regulation of differentiation and proliferation of embryonic cardiomyocytes by a jumonji (Jarid2)-cyclin D1 pathway.

MEF2A MEF2C MEF2D

1.09e-0513119321447557
Pubmed

Cloning and functional characterization of GNPI2, a novel human homolog of glucosamine-6-phosphate isomerase/oscillin.

GNPDA1 GNPDA2

1.16e-052119212616532
Pubmed

Polymorphisms of the DNA repair gene XPA and XPC and its correlation with gastric cardiac adenocarcinoma in a high incidence population in North China.

XPA XPC

1.16e-052119218645534
Pubmed

Regulation of Akt(ser473) phosphorylation by choline kinase in breast carcinoma cells.

CHKA AKT1

1.16e-052119220042122
Pubmed

Genetic variants of nucleotide excision repair genes are associated with DNA damage in coke oven workers.

XPA XPC

1.16e-052119220056640
Pubmed

IL-4 regulates COX-2 and PGE2 production in human non-small cell lung cancer.

PTGS2 IL4

1.16e-052119216574063
Pubmed

Loss of myocyte enhancer factor 2 expression in osteoclasts leads to opposing skeletal phenotypes.

MEF2A MEF2D

1.16e-052119232512162
Pubmed

Increased rates of cerebral glucose metabolism in a mouse model of fragile X mental retardation.

FMR1 IL4

1.16e-052119212427968
Pubmed

Molecular Pathway to Protection From Age-Dependent Photoreceptor Degeneration in Mef2 Deficiency.

MEF2C MEF2D

1.16e-052119228738418
Pubmed

The transcription factors TBX2 and TBX3 interact with human papillomavirus 16 (HPV16) L2 and repress the long control region of HPVs.

TBX3 TBX2

1.16e-052119223388722
Pubmed

Identification of TBX2 and TBX3 variants in patients with conotruncal heart defects by target sequencing.

TBX3 TBX2

1.16e-052119230223900
Pubmed

Overexpression of myocyte enhancer factor 2 and histone hyperacetylation in hepatocellular carcinoma.

MEF2A MEF2C

1.16e-052119217611778
Pubmed

The T-box transcription factors TBX2 and TBX3 in mammary gland development and breast cancer.

TBX3 TBX2

1.16e-052119223624936
Pubmed

Intestinal toxicity and carcinogenic potential of the food mutagen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in DNA repair deficient XPA-/- mice.

XPA XPC

1.16e-052119211285198
Pubmed

Expression of p-Akt and COX-2 in gastric adenocarcinomas and adenovirus mediated Akt1 and COX-2 ShRNA suppresses SGC-7901 gastric adenocarcinoma and U251 glioma cell growth in vitro and in vivo.

PTGS2 AKT1

1.16e-052119219925030
Pubmed

T-cell glucocorticoid receptor is required to suppress COX-2-mediated lethal immune activation.

NR3C1 PTGS2

1.16e-052119212949501
Pubmed

Polymorphisms of the DNA repair gene xeroderma pigmentosum groups A and C and risk of esophageal squamous cell carcinoma in a population of high incidence region of North China.

XPA XPC

1.16e-052119217653764
Pubmed

Prognostic significance of cyclooxygenase 2 and phosphorylated Akt1 overexpression in primary nonmetastatic and metastatic cutaneous melanomas.

PTGS2 AKT1

1.16e-052119228604419
Pubmed

Stratification based on methylation of TBX2 and TBX3 into three molecular grades predicts progression in patients with pTa-bladder cancer.

TBX3 TBX2

1.16e-052119225394776
Pubmed

The flowering repressor SVP underlies a novel Arabidopsis thaliana QTL interacting with the genetic background.

SRF MEF2C

1.16e-052119223382706
Pubmed

Mouse models for xeroderma pigmentosum group A and group C show divergent cancer phenotypes.

XPA XPC

1.16e-052119218316597
Pubmed

The survival impact of XPA and XPC genetic polymorphisms on patients with esophageal squamous cell carcinoma.

XPA XPC

1.16e-052119222941172
Pubmed

The Selective Glucocorticoid Receptor Modulator Cort 113176 Reduces Neurodegeneration and Neuroinflammation in Wobbler Mice Spinal Cord.

VPS54 NR3C1

1.16e-052119229890290
Pubmed

IGF2BP2, an RNA-binding protein regulates cell proliferation and osteogenic differentiation by stabilizing SRF mRNA.

SRF IGF2BP2

1.16e-052119236436184
Pubmed

Glucocorticoid receptor changes its cellular location with breast cancer development.

NR3C1 PTGS2

1.16e-052119217952860
Pubmed

A Late Phase of Long-Term Synaptic Depression in Cerebellar Purkinje Cells Requires Activation of MEF2.

MEF2A MEF2D

1.16e-052119230699340
Pubmed

Exploring the mammalian neuromuscular system by analysis of mutations: spinal muscular atrophy and myotonia.

VPS54 CLCN1

1.16e-05211928008830
Pubmed

Myocyte enhancer factors 2A and 2C induce dilated cardiomyopathy in transgenic mice.

MEF2A MEF2C

1.16e-052119216469744
Pubmed

Restoration of impaired endothelial myocyte enhancer factor 2 function rescues pulmonary arterial hypertension.

MEF2A MEF2C

1.16e-052119225336633
Pubmed

Two mammalian glucosamine-6-phosphate deaminases: a structural and genetic study.

GNPDA1 GNPDA2

1.16e-052119212965206
Pubmed

MEF2B is a component of a smooth muscle-specific complex that binds an A/T-rich element important for smooth muscle myosin heavy chain gene expression.

MEF2B MEF2A

1.16e-05211929430690
Pubmed

Clinical profile and mutation analysis of xeroderma pigmentosum in Indian patients.

XPA XPC

1.16e-052119225566891
Pubmed

Potential risk of esophageal squamous cell carcinoma due to nucleotide excision repair XPA and XPC gene variants and their interaction among themselves and with environmental factors.

XPA XPC

1.16e-052119226831662
Pubmed

Angelman syndrome protein UBE3A interacts with primary microcephaly protein ASPM, localizes to centrosomes and regulates chromosome segregation.

UBE3A ASPM

1.16e-052119221633703
Pubmed

Regulation of myocyte enhancer factor-2 transcription factors by neurotoxins.

MEF2A MEF2C

1.16e-052119221741404
Pubmed

Early cardiac hypertrophy in mice with impaired calmodulin regulation of cardiac muscle Ca release channel.

MEF2A RYR2

1.16e-052119217431507
Pubmed

Fragile X mental retardation protein is required for synapse elimination by the activity-dependent transcription factor MEF2.

FMR1 MEF2A

1.16e-052119220434996
Pubmed

Distinct roles for the Charcot-Marie-Tooth disease-causing endosomal regulators Mtmr5 and Mtmr13 in axon radial sorting and Schwann cell myelination.

SBF1 SBF2

1.16e-052119234718573
InteractionMEF2B interactions

MEF2B MEF2A MEF2C MEF2D

3.57e-07111184int:MEF2B
InteractionBORCS8-MEF2B interactions

MEF2B MEF2A MEF2C MEF2D

1.45e-06151184int:BORCS8-MEF2B
InteractionFBXW7 interactions

CUL4B RPL37A FMR1 SPTBN1 RPS9 RPS10 ABCF2 MYO1B XPA NR3C1 XRCC4 SUCLG1 IGF2BP2 PNPLA6 TIMP4 SUB1 SBF2 SMARCA1 PYGL AKT1 MRTO4 SNRNP200

1.94e-06121511822int:FBXW7
InteractionMEF2C interactions

MEF2B SPTBN1 MEF2A MEF2C MEF2D

1.59e-05541185int:MEF2C
InteractionECT2 interactions

FMR1 RBMXL3 MYO1A SPTB SPTBN1 RPS9 RPS10 POR MYO1B SUCLG1 PICALM IGF2BP2 ASPM RACGAP1 MRTO4 SNRNP200 MRPL1

1.60e-0588711817int:ECT2
InteractionKIF23 interactions

FMR1 RBMXL3 MYO1A SPTBN1 RPS9 RPS10 POR MYO1B AK9 IGF2BP2 TNRC18 CLCN1 ASPM RACGAP1 PRKAR2A PRKCI MRTO4 SNRNP200

3.06e-05103111818int:KIF23
GeneFamilyMyocyte enhancer factor 2 proteins|MADS box family

MEF2B SRF MEF2A MEF2C MEF2D

1.15e-1257651086
GeneFamilyMyocyte enhancer factor 2 proteins|MADS box family

MEF2B MEF2A MEF2C MEF2D

2.88e-104764649
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

SPTB SPTBN1 SBF1 CADPS SBF2 AKT1 SNTB1

2.53e-05206767682
GeneFamilyEF-hand domain containing|Spectrins

SPTB SPTBN1

3.61e-0477621113
GeneFamilyWD repeat domain containing|Xeroderma pigmentosum complementation groups|Nucleotide excision repair

XPA XPC

4.80e-0487621125
GeneFamilyMyosins, class I

MYO1A MYO1B

4.80e-0487621097
GeneFamilyMyotubularins|Phosphoinositide phosphatases

SBF1 SBF2

1.77e-0315762903
GeneFamilyT-boxes

TBX3 TBX2

2.55e-0318762766
GeneFamilyGuanylate cyclase receptors|DENN/MADD domain containing

SBF1 SBF2

4.91e-0325762504
GeneFamilyPyrin domain containing|Pyrin and HIN domain family

NLRP10 MNDA

4.91e-0325762994
CoexpressionCAIRO_HEPATOBLASTOMA_CLASSES_UP

KNTC1 SUPT3H RPL37A TEX2 RPS9 ABCF2 MDN1 ASPM SMARCA1 PYGL MRTO4 SNRNP200 SNTB1

4.39e-0661211913M4772
CoexpressionNAKAYA_PLASMACYTOID_DENDRITIC_CELL_FLUMIST_AGE_18_50YO_7DY_UP

CUL4B SUPT3H FMR1 SPTBN1 NR3C1 XRCC4 MEF2A MEF2C SHQ1 NCBP3 SIDT2 MDN1 UBE3A PRKCI OTULINL SNRNP200 UBFD1

3.52e-05121511917M41122
CoexpressionGSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_HET_4H_DN

VPS26B TEX2 XPA MEF2C TNRC18 OTULINL MNDA

3.58e-051991197M8707
CoexpressionGSE17721_LPS_VS_PAM3CSK4_16H_BMDC_DN

RPL37A RPS9 TMEM135 RPS10 MYO1B MEF2A EFCAB7

3.69e-052001197M3929
CoexpressionGSE16385_ROSIGLITAZONE_VS_UNTREATED_IFNG_TNF_STIM_MACROPHAGE_UP

MYO1B TUFT1 IGF2BP2 PKD2L2 ATP11B FBXO42 EFCAB7

3.69e-052001197M7894
CoexpressionAtlasdev gonad_e11.5_M_SupCellPrec_Sry_top-relative-expression-ranked_500

CUL4B SOX5 CHKA RYR2 GXYLT2 SIDT2 IGF2BP2 TNRC18 SLC26A7 CADPS SMARCA1

2.73e-0543211711gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_500
CoexpressionAtlasDevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#2_top-relative-expression-ranked_500

MED18 SPTBN1 GRIK1 NCBP3 TNRC18 UBE3A ASPM

3.24e-051621177gudmap_developingGonad_e16.5_epididymis_500_k2
CoexpressionAtlasdev gonad_e11.5_M_SupCellPrec_Sry_k-means-cluster#3_top-relative-expression-ranked_500

SOX5 CHKA SIDT2 IGF2BP2 TNRC18 SMARCA1

6.19e-051231176gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_k3_500
ToppCellmild-immature_Neutrophil|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

KNTC1 CHKA SHQ1 IGF2BP2 ASPM

2.93e-06831195f7225bc24ad6df3a41375cc4614af824e0db3559
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

SOX5 TBX3 SPTB MYO1B RYR2 TBX2

8.45e-061781196185b44700f06ec58b3c09c80520502166c965fd6
ToppCellAdult-Mesenchymal-pericyte_cell-D122|Adult / Lineage, Cell type, age group and donor

GABRB2 SOX5 TBX3 SPTB RYR2 TBX2

9.89e-061831196fc31a43a637423cb3bb9aa184a3a889a0b9aaea6
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 MYO1B MEF2C CADPS ARHGAP44 TBX2

1.05e-05185119651dfe6ac7df8b330343b37e3bee71e5c65267189
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 MYO1B MEF2C CADPS ARHGAP44 TBX2

1.05e-051851196a8c02cec3c414f3a0da9f2d6d28ce563b0030705
ToppCellmild-immature_Neutrophil|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

KNTC1 CHKA SHQ1 IGF2BP2 ASPM

1.12e-0510911952f03d6ee8b13424cc6a5bc60ac3461b44dff9d79
ToppCellAdult-Mesenchymal-pericyte_cell|Adult / Lineage, Cell type, age group and donor

GABRB2 SOX5 TBX3 SPTB RYR2 TBX2

1.12e-05187119662759efb660179402fb574ce5701c89a2e17bcfe
ToppCellCOVID-19-Heart-CM_4|Heart / Disease (COVID-19 only), tissue and cell type

SPTB MYOM3 POR IGF2BP2 SAT1 CADPS

1.22e-0519011963729648a17093b438398b82e32bbccc3af7b8c5d
ToppCellCOVID-19-Heart-EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

SOX5 CDK17 ANO2 MYO1B MEF2C TBX2

1.22e-051901196a21653bfb7bafbc273f94fa7c13bfb48cf8fd562
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GABRB2 TBX3 MYO1B RYR2 OTULINL TBX2

1.26e-0519111961626b23a57429f835fddc052e3c57f63a4e5b8bb
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GABRB2 TBX3 MYO1B RYR2 OTULINL TBX2

1.26e-051911196716dfa7fccbd62b5f574792e68a26dc6c45511dc
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_INF-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CNBD1 MEF2A MEF2C SAT1 OTULINL MNDA

1.30e-051921196935a4a36881a9fa4daa02cba96af07f6686ed8d6
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SOX5 TBX3 RPL37A NEBL RPS9 TBX2

1.30e-0519211964c9d748f209cc1e13d28c8c7f5180ab8522e0fbf
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SOX5 TBX3 RPL37A NEBL CDCA7 TBX2

1.30e-051921196c4efc170852abbcf0c53c2b0f8a0cc9fe7f116c8
ToppCellCF-Lymphoid|CF / Disease state, Lineage and Cell class

SOX5 SUPT3H BCAS4 MEF2C MDN1 MRPL1

1.34e-05193119611de07d13a7da223990b56fa89ba7fc1c3dd0122
ToppCellcontrol-Epithelial-Basal|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

RPL37A RPS9 RPS10 MEF2C MNDA

1.39e-051141195276e32c2e04c4c060078cd5277ac5a9ae02033f8
ToppCellfacs-Brain_Myeloid-Hippocampus|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO1B NR3C1 MEF2A PICALM MEF2C NCBP3

1.42e-051951196a1478021a3ed0e779716393124ca2a7770c433b7
ToppCellMid-temporal_gyrus_(MTG)-Neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GABRB2 MEF2C RYR2 UBE3A CADPS ARHGAP44

1.46e-051961196676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCelltumor_Lung-Fibroblasts-COL13A1+_matrix_FBs|Fibroblasts / Location, Cell class and cell subclass

RPL37A NEBL SPTBN1 RPS10 CIBAR1 TBX2

1.50e-05197119644f37a98f07c3e46a7e8fd3b64c2b2b44d5bbe40
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GABRB2 MEF2C RYR2 UBE3A CADPS ARHGAP44

1.55e-051981196c01091ef18e096d792ea2a7a715764a5b215355f
ToppCellprimary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GABRB2 MEF2C RYR2 UBE3A CADPS ARHGAP44

1.55e-0519811966d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GABRB2 MEF2C RYR2 UBE3A CADPS ARHGAP44

1.55e-0519811968ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GABRB2 MEF2C RYR2 UBE3A CADPS ARHGAP44

1.55e-0519811964ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GABRB2 MEF2C RYR2 UBE3A CADPS ARHGAP44

1.55e-0519811960ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCellParenchymal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NEBL MYO1B CHKA ARHGAP44 PRKCI SNTB1

1.59e-0519911965cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCellCaecum-B_cell-B_cell_memory|Caecum / Region, Cell class and subclass

RPL37A RPS9 RPS10 BCAS4 MEF2C MNDA

1.64e-0520011965a954d366762c6838cc6ec3ae05ed908e5f120b5
ToppCellParenchyma_Control_(B.)-Stromal-TX-Smooth_muscle-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

GABRB2 SOX5 TBX3 MYO1B RYR2 TBX2

1.64e-0520011960c648941447c738caf62f2d71e296d6cca492c8b
ToppCellTracheal-10x3prime_v2-Stromal-Pericyte-Muscle_pericyte_pulmonary|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

GABRB2 TBX3 MYO1B MEF2C RYR2 TBX2

1.64e-0520011968158f4eaeff945a6788c8e732b7a1b0d78052a06
ToppCellNeuronal|World / cells hierarchy compared to all cells using T-Statistic

GABRB2 MEF2C RYR2 UBE3A CADPS ARHGAP44

1.64e-05200119648d801219bc771d6c7e151dc88ca4c179988de85
ToppCellCaecum-(2)_B_cell-(22)_B_cell_memory|Caecum / shred on region, Cell_type, and subtype

RPL37A RPS9 RPS10 BCAS4 MEF2C MNDA

1.64e-0520011968e71f3518cde586fe0b8dfa3f6ee57e85e10ad4e
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GABRB2 SOX5 TBX3 MYO1B RYR2 TBX2

1.64e-052001196522a51a284d2992d519c4669e1a48c8ebcc08c80
ToppCellTracheal-10x3prime_v2-Stromal-Pericyte|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

GABRB2 TBX3 MYO1B MEF2C RYR2 TBX2

1.64e-052001196600d56257b1b0cda8ed2fd0db92c6551711f7d6d
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

GABRB2 SOX5 TBX3 MYO1B RYR2 TBX2

1.64e-05200119694f1fa61aa82eb9f411b2b1cb759476939ab5db7
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

RBMXL3 PTGS2 SAT1 MNDA IL4

3.60e-051391195fa0eedebf53317928022c3bed391ce99a2114f98
ToppCellLymphoid-Lymphoid-NK_cells|Lymphoid / shred on cell class and cell subclass (v4)

MYO1B MEF2A PICALM ZNF879 IGF2BP2

4.86e-051481195d51a4b654a88d58dcdf29c2bc362c0cc1c40723a
ToppCell368C-Lymphocytic-CD4_T-cell-CD4+_Naive_T_cell_/_CD4+_Trm_cell|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

MAK FZD9 SBF1 ARHGAP44 PYGL

7.04e-05160119519105debef96ea0c267d6a1d332303ec668ae47e
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb-18m-Mesenchymal-skeletal_muscle_satellite_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAD1 RPL37A RPS9 RPS10 GRIK1

7.25e-051611195d02f8c01b26158a06e109eb603b0fe76372ec983
ToppCellPND28-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RPL37A RPS9 SAT1 PYGL MNDA

8.14e-0516511951d844d19ff9b49dd0f61f0b24799e172076771ef
ToppCellPND28-Immune-Immune_Myeloid-Monocytic-Macrophage|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RPL37A RPS9 SAT1 PYGL MNDA

8.14e-0516511959a6abd0e6b11860231ce5e845c87b8d66f3ef697
ToppCellPND28-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RPL37A RPS9 SAT1 PYGL MNDA

8.14e-051651195433771abefc5bcb89bdae64af45cce7407bffe5d
ToppCellPND28-Immune-Immune_Myeloid|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RPL37A RPS9 SAT1 PYGL MNDA

8.37e-051661195caa992944bc7488a6868dbd1902bc3ead6945eb1
ToppCellInfluenza_Severe-Neutrophil|World / Disease group and Cell class

MAK PTGS2 SAT1 PYGL MNDA

9.11e-0516911956e8e2580e19c96bcf7fa6a6d8c183df65f428396
ToppCellnormal_Lung-Fibroblasts-Pericytes|Fibroblasts / Location, Cell class and cell subclass

GABRB2 MYO1B MEF2C OTULINL TBX2

9.37e-051701195d69c0ea4cb6b204f19d0a5d2164afb42184779ac
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TBX3 MEF2C RYR2 SLC35G1 SNTB1

9.37e-0517011955570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCellsevere_influenza-Neutrophil|severe_influenza / disease group, cell group and cell class (v2)

MAK TDP2 SAT1 PYGL MNDA

1.02e-041731195615e266419b9f06e964eff73cb466f05451ba0dd
ToppCelldroplet-Liver-Npc-18m-Myeloid-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPL37A IGF2BP2 SAT1 SDC3 OTULINL

1.02e-0417311959ba55e21d1037ec3150d77895e52f0b051df65da
ToppCell5'-Adult-LargeIntestine-Hematopoietic-B_cells-Cycling_B_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MEF2B BCAS4 MEF2C PXK ASPM

1.02e-041731195b7e0193fd4983cb38d1bee441f608f73ee8743b9
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PXK TMCO4 SLC26A7 RACGAP1 SNTB1

1.04e-0417411955f4436863a40f8bca46e2989bca66c02b6be88d4
ToppCellControl-Epithelial_cells-AT1|Control / group, cell type (main and fine annotations)

NEBL SPTBN1 MYO1B ARHGAP44 OTULINL

1.04e-041741195548d7f2b958a2bfd2c95eb049ceaab55a559c77d
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RPL37A RPS9 RPS10 MEF2C PXK

1.04e-0417411959aa2168d3bcef7cdc5a47442618cb8e9eb24c95b
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PXK TMCO4 SLC26A7 RACGAP1 SNTB1

1.07e-04175119577c16e615c0fb9c83f29d7e0a547be72635fac81
ToppCellfacs-Skin-nan-18m-Epithelial-inner_bulge|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAK RPL37A DOK7 RPS9 ARHGAP44

1.10e-041761195086197acbfec4ac0c15b7e9721871aaa9e32e219
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 PXK TMCO4 SLC26A7 SNTB1

1.13e-041771195f35b04c3557ebbdeba37dec54c8f45880eafb422
ToppCell(3)_Chondrocytes-(32)_Chondro-prehyper-2|World / Cell class and subclass of bone marrow stroma cells in homeostatis

SUPT3H MEF2C FZD9 GXYLT2 SDC3

1.16e-041781195c569a406c3ae183a278d8540e8eba58f4f26c5b0
ToppCellfacs-BAT-Fat-3m-Lymphocytic-T_cell|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPL37A ATP11B RAB3IP OTULINL SNTB1

1.16e-0417811957c101e3957ea9b0d4ebf619d1d02e7e64ae28915
ToppCelldroplet-Lung-21m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KNTC1 SUPT3H CHKA SDC3 MNDA

1.19e-0417911954f20540bfbcefe0e83812be7ea542e8bb3bf19bc
ToppCelldroplet-Lung-18m-Mesenchymal-myofibroblast-pericyte_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SOX5 MYO1B RYR2 SMARCA1 TBX2

1.19e-041791195f5bb4d3a27d56698473219970e764084096cc582
ToppCelldroplet-Limb_Muscle-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPL37A RPS9 RPS10 PTGS2 MNDA

1.19e-041791195013818e173101efca7625ccd4258e60655815d73
ToppCellCOVID-19-kidney-REN+Pericyte|kidney / Disease (COVID-19 only), tissue and cell type

SOX5 TBX3 MYO1B MEF2C TBX2

1.19e-041791195342c1cc4444f51b8dcb30d3adc98285a25669c6e
ToppCelldroplet-Lung-18m-Mesenchymal-myofibroblast-pericyte_cell-pericyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SOX5 MYO1B RYR2 SMARCA1 TBX2

1.19e-041791195fa03ec3cc0132f977b4cb28e7b23789732375183
ToppCell3'-GW_trimst-2-LargeIntestine-Epithelial-epithelial_progenitor_cell-TA|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GABRB2 CDCA7 TIMP4 ASPM RACGAP1

1.22e-041801195271ee52ed8f21f78ddf68e52fc88fe582701675e
ToppCellCV-Healthy-2|CV / Virus stimulation, Condition and Cluster

RPL37A ABCF2 ASPM SMARCA1 MRTO4

1.22e-041801195e182e5c495dd82d4fcbf1a920086c70b064801f3
ToppCelldroplet-Lung-nan-18m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX5 MYO1B RYR2 SMARCA1 TBX2

1.22e-041801195f6a05b3751b01e74b2de8440801b0eb2e723c199
ToppCelldroplet-Lung-nan-18m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX5 MYO1B RYR2 SMARCA1 TBX2

1.22e-041801195dfc75ae4395ff46fbec2c54915d98ead5a1ba1a1
ToppCellCOVID-19_Convalescent|World / Disease condition and Cell class

RPL37A RPS9 RPS10 RAB24 MNDA

1.26e-041811195a62115a8da486fc61225901c72b1ec70bcaf4c36
ToppCellLA-11._Adipocyte|LA / Chamber and Cluster_Paper

SOX5 TMEM135 CHKA SAT1 SNTB1

1.32e-0418311953f9011976782fa8aa95cdd6f00f07a91094d411b
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SOX5 MYO1B RYR2 SLC35G1 TBX2

1.32e-0418311958a799807fbf24456a9811e0c64068187940a2f71
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SOX5 MYO1B RYR2 SLC35G1 TBX2

1.36e-041841195689a8af81a79a4bb3123cfa01958c953eab5de98
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-enteroendocrine_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GXYLT2 CADPS SMARCA1 OTULINL SNTB1

1.36e-0418411953da93e7d8b62463e307cc0425c47dbd3bef66799
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Degenerative_Cortical_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RPL37A PXK SLC26A7 RACGAP1 SNTB1

1.36e-041841195282118f8221fa383ffb81dfb5798a0b7f065f911
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D122|Adult / Lineage, Cell type, age group and donor

NEBL SPTBN1 MYO1B ARHGAP44 OTULINL

1.36e-041841195561592edc3083fad41b91811151b442207c65dd9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 MYO1B MEF2C CADPS ARHGAP44

1.39e-0418511957092436b4db90289516ed130ade596e3021cffaf
ToppCellCOVID-19-Heart-CM_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

NEBL SPTB MYOM3 RYR2 CADPS

1.39e-041851195549eeb521c3985bff396ea0f202db21822efa51f
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D175|Adult / Lineage, Cell type, age group and donor

NEBL SPTBN1 MYO1B PTGS2 ARHGAP44

1.39e-04185119532b4e68e551d435a732f253f6ad83408c759a642
ToppCelldroplet-Fat-Mat-18m-Lymphocytic-B_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEF2B RPL37A RPS9 RPS10 MEF2C

1.39e-04185119598bb853c495eb16c3663685a8e20755bd309b520
ToppCellkidney_cells-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

RPS9 RPS10 SUCLG1 SAT1 SUB1

1.39e-0418511958b381706b656d366b63adb9703db1c3dc796b3f8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 MYO1B MEF2C CADPS ARHGAP44

1.39e-041851195a8ca7819066d5297ef6966e7f3e2c9f8a7673fdc
ToppCellCOVID-19-Fibroblasts-Pericytes|COVID-19 / group, cell type (main and fine annotations)

SOX5 TBX3 MYO1B RYR2 TBX2

1.39e-0418511954905adaeeffd353e089578e5ea614437dbe794e6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Degenerative_Cortical_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RPL37A PXK SLC26A7 RACGAP1 SNTB1

1.39e-0418511959438097e94219c1db922b8507e3a29106d32a923
ToppCellInfluenza-Influenza_Severe-Myeloid-Neutrophil|Influenza_Severe / Disease, condition lineage and cell class

SOX5 MAK SAT1 PYGL MNDA

1.43e-0418611951dfcec9196d4db76fba3abc74e85885b1fb98b87
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GABRB2 TBX3 MYO1B RYR2 TBX2

1.43e-041861195888e85a025bd982d36c910db0f5a3385b1ca3b28
ToppCellCOPD-Stromal-Pericyte|World / Disease state, Lineage and Cell class

SOX5 TBX3 MYO1B RYR2 TBX2

1.43e-0418611958adfd2d1fda4e8aecc95192ea627bf7ed5214b8d
ToppCell356C-Lymphocytic-CD4_T-cell-Proliferating_T_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

IGF2BP2 CDCA7 CIBAR1 ASPM PYGL

1.43e-041861195722da08cd978249a19855fd3ec8ddda780c99d83
ToppCell5'-GW_trimst-2-LymphNode-Mesenchymal-Pericytes-angiogenic_pericyte|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MAGEA11 TNFAIP8L3 SPTB MYO1B MEF2C

1.46e-041871195b8f88599e22b9b345c7ec3bbecd87a8b2a033f9f
ToppCelldroplet-Mammary_Gland-nan-21m-Lymphocytic-nan|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPL37A RPS9 RPS10 MEF2C SUB1

1.46e-04187119516b2fddf2c23a29f173102f117876c9df5544ae4
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX5 KNTC1 CDCA7 ASPM RACGAP1

1.46e-04187119538ee33295a21db4aae5ba085df033db9693e41c6
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX5 KNTC1 CDCA7 ASPM RACGAP1

1.46e-041871195dbcec24d2c852964736c78e9d81650bff5c455ae
ToppCelldroplet-Kidney-nan-18m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANO2 TBX3 NEBL PTGS2 TIMP4

1.46e-041871195e93cad16a087d1443cbf4e1690dc1b35d7a84c41
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

SOX5 TBX3 MYO1B RYR2 TBX2

1.50e-041881195ee151792c7ac9afe820f1a281c6dab383799f358
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MEF2B SPTB MEF2C SLC26A7 TBX2

1.50e-041881195c2321a3a1d9603f8b4b4fc09707eb32ec1e04f3f
ToppCellMesenchymal-pericyte_cell|World / Lineage, Cell type, age group and donor

SOX5 TBX3 MYO1B RYR2 TBX2

1.54e-041891195d7ed96add29f219183c802895fbff519b627f635
ToppCellCF-Lymphoid-B_cell|CF / Disease state, Lineage and Cell class

SOX5 BCAS4 MEF2C MDN1 MRPL1

1.58e-041901195374d8fd63c733178acab07682ed1519693efab45
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_1-Pericyte|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

GABRB2 SOX5 MYO1B RYR2 TBX2

1.58e-0419011954eb92aef1ee868f4537483d19014d947b7684612
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NEBL PXK SLC26A7 SNTB1 TBX2

1.58e-041901195b3bccf4dd95e986db3cee324a6737f5fcc22e8e5
ToppCellCOVID-19-kidney-AQP1+SLC14A1+EC|kidney / Disease (COVID-19 only), tissue and cell type

SOX5 CDK17 ANO2 PTGS2 MEF2C

1.58e-0419011951519f34d31fe0817184c5865a0bc9f0cb479b1a4
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

NEBL SPTBN1 MYO1B TUFT1 ARHGAP44

1.58e-04190119530b50d183d7649146eb1e79b47ba897355f1998a
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

GABRB2 SOX5 MYO1B RYR2 TBX2

1.58e-0419011957be4341e2909101d756f14031c21e705eb45e69a
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_B-ABC_aged-B_memory|lymph-node_spleen / Manually curated celltypes from each tissue

SOX5 BCAS4 MEF2A MEF2C PXK

1.62e-041911195c3ca8077da8594fb493e47ac4dfbbd20bfc14b37
ToppCell10x5'-Lung-Myeloid_Monocytic-Nonclassical_monocytes|Lung / Manually curated celltypes from each tissue

RPS9 MEF2C SIDT2 RAB24 SAT1

1.62e-041911195a862a571625ab7238589ff201e5954f602c3bd7e
ToppCellEpithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|World / Lineage, Cell type, age group and donor

SOX5 NEBL MYO1B ARHGAP44 PRKCI

1.62e-041911195d3733c8c4bda70c4390e5601fdda6188a64be944
Drugciglitazone

TNFAIP8L3 NR3C1 PTGS2 SAT1 TIMP4 AKT1 SNRNP200 IL4

3.04e-061691198CID000002750
Drug0198306-0000 [212631-61-3]; Down 200; 10uM; MCF7; HT_HG-U133A

NEBL ABCF2 CHKA PICALM SIDT2 PNPLA6 SBF1 FBXO42

8.73e-0619511987099_DN
DrugZuclopenthixol hydrochloride [633-59-0]; Down 200; 9.2uM; HL60; HT_HG-U133A

CDK17 POR MYO1B MEF2C RYR2 IGF2BP2 SBF1 SNTB1

9.07e-0619611982936_DN
Drug(+,-)-Octopamine hydrochloride [770-05-8]; Down 200; 21uM; HL60; HT_HG-U133A

GABRB2 SPTBN1 IQSEC2 ABCF2 MEF2A IGF2BP2 SBF1 OTULINL

9.76e-0619811983112_DN
DrugMerbromin [129-16-8]; Down 200; 5uM; HL60; HT_HG-U133A

GABRB2 SUPT3H XRCC4 MEF2C RYR2 ARHGAP44 MAP2K7 TBX2

1.01e-0519911982577_DN
Diseaseintellectual disability (implicated_via_orthology)

CUL4B MEF2B MEF2A MEF2C MEF2D UBE3A

4.97e-07751156DOID:1059 (implicated_via_orthology)
DiseaseEpilepsy, Cryptogenic

GABRB2 IQSEC2 MEF2C UBE3A AKT1

1.77e-05821155C0086237
DiseaseAwakening Epilepsy

GABRB2 IQSEC2 MEF2C UBE3A AKT1

1.77e-05821155C0751111
DiseaseAura

GABRB2 IQSEC2 MEF2C UBE3A AKT1

1.77e-05821155C0236018
Diseaseautism spectrum disorder (implicated_via_orthology)

MEF2B FMR1 MEF2A MEF2C MEF2D UBE3A

3.00e-051521156DOID:0060041 (implicated_via_orthology)
DiseaseSchizophrenia

GABRB2 SOX5 FMR1 GRIK1 IDE NR3C1 XRCC4 PTGS2 IGF2BP2 SLC26A7 AKT1 MAP2K7 IL4

4.15e-0588311513C0036341
DiseaseFibrosis

PTGS2 AKT1 MAP2K7 IL4

4.39e-05501154C0016059
DiseaseCirrhosis

PTGS2 AKT1 MAP2K7 IL4

4.39e-05501154C1623038
DiseaseEpilepsy

GABRB2 IQSEC2 MEF2C UBE3A AKT1

6.97e-051091155C0014544
Diseasespinocerebellar ataxia type 5 (implicated_via_orthology)

SPTB SPTBN1

8.99e-0541152DOID:0050882 (implicated_via_orthology)
DiseaseXeroderma Pigmentosum

XPA XPC

8.99e-0541152C0043346
DiseaseCardiomyopathies

NEBL PTGS2 RYR2 AKT1 IL4

1.60e-041301155C0878544
Diseaseattention deficit hyperactivity disorder (implicated_via_orthology)

MEF2A MEF2C MEF2D

1.76e-04281153DOID:1094 (implicated_via_orthology)
Diseaseprostate carcinoma in situ (is_marker_for)

PTGS2 TIMP4 MAP2K7

1.76e-04281153DOID:8634 (is_marker_for)
Diseasexeroderma pigmentosum (is_implicated_in)

XPA XPC

2.24e-0461152DOID:0050427 (is_implicated_in)
Diseasecortical thickness

SOX5 ANO2 CNBD1 SUPT3H RPL37A SPTBN1 MEF2C PXK FZD9 CADPS FBXO42 PRKAR2A SNTB1

4.06e-04111311513EFO_0004840
Diseaseheart disease (implicated_via_orthology)

SOX5 RYR2 MAP2K7

4.40e-04381153DOID:114 (implicated_via_orthology)
DiseaseMood Disorders

GABRB2 NR3C1 PTGS2 SAT1 AKT1

5.22e-041681155C0525045
Diseasephosphatidylinositol measurement

ANO2 DOK7 RPS9 SLCO1B3

5.30e-04951154EFO_0010230
DiseaseXeroderma pigmentosum

XPA XPC

5.32e-0491152cv:C0043346
Diseaselung cancer (implicated_via_orthology)

XPC PTGS2

5.32e-0491152DOID:1324 (implicated_via_orthology)
DiseaseCutaneous Melanoma

XPA XPC AKT1

5.52e-04411153C0151779
DiseaseAutistic Disorder

FMR1 XPC PTGS2 MEF2C UBE3A IL4

5.69e-042611156C0004352
Diseasecholesteryl ester 22:5 measurement

DOK7 SIDT2

6.64e-04101152EFO_0021444
Diseasetype 2 diabetes mellitus (implicated_via_orthology)

IDE NR3C1 AKT1 PRKCI

7.73e-041051154DOID:9352 (implicated_via_orthology)
DiseasePremature Birth

PTGS2 IL4

8.09e-04111152C0151526
DiseaseBasal cell carcinoma

XPA XPC

8.09e-04111152C0007117
DiseaseCondition, Preneoplastic

CCDC134 PTGS2 AKT1 MAP2K7

9.20e-041101154C0282313
DiseasePrecancerous Conditions

CCDC134 PTGS2 AKT1 MAP2K7

9.20e-041101154C0032927
Diseaseglycerophospholipid measurement

ANO2 DOK7 SIDT2

9.32e-04491153EFO_0007630
Diseasedisks large homolog 3 measurement

MEF2C MEF2D

9.69e-04121152EFO_0802472
Diseasepancreatic cancer (is_implicated_in)

XPC PTGS2 AKT1 IL4

9.84e-041121154DOID:1793 (is_implicated_in)
Diseasevelocity of sound measurement

SPTBN1 TMEM135

1.14e-03131152EFO_0005654
DiseaseCharcot-Marie-Tooth disease type 4

SBF1 SBF2

1.14e-03131152cv:C4082197
DiseaseObesity

PTGS2 SAT1 GNPDA2 SDC3 AKT1

1.27e-032051155C0028754
DiseaseSquamous cell carcinoma

XPA XPC PTGS2 AKT1

1.43e-031241154C0007137
DiseaseAlzheimer's disease (implicated_via_orthology)

SOX5 IDE PTGS2

1.45e-03571153DOID:10652 (implicated_via_orthology)
DiseaseLibman-Sacks Disease

PTGS2 PXK IL4

1.52e-03581153C0242380
Diseaseforehead morphology measurement

SUPT3H GRIK1

1.53e-03151152EFO_0007844
Diseasetumor necrosis factor beta measurement

CCDC134 SNTB1

1.53e-03151152EFO_0008308
DiseaseMalignant neoplasm of skin

XPA PTGS2 AKT1

1.60e-03591153C0007114
DiseaseSkin Neoplasms

XPA PTGS2 AKT1

1.60e-03591153C0037286
Diseasehypertension (implicated_via_orthology)

SRF NR3C1 PTGS2 AKT1

1.61e-031281154DOID:10763 (implicated_via_orthology)
Diseaserenal cell carcinoma (is_marker_for)

NR3C1 PTGS2 TIMP4 AKT1

1.61e-031281154DOID:4450 (is_marker_for)
DiseaseChromosome Aberrations

XPC XRCC4

1.74e-03161152C0008625
DiseaseAutosome Abnormalities

XPC XRCC4

1.74e-03161152C0004403
DiseasePolyposis, Adenomatous Intestinal

PTGS2 AKT1

1.74e-03161152C2713442
DiseaseFamilial Intestinal Polyposis

PTGS2 AKT1

1.74e-03161152C2713443
Diseaseimmunoglobulin lambda-like polypeptide 1 measurement

SUPT3H MEF2C

1.74e-03161152EFO_0801688
DiseaseAdenomatous Polyposis Coli

PTGS2 AKT1

1.97e-03171152C0032580
Diseasenoggin measurement

MEF2C MEF2D

2.21e-03181152EFO_0021995
Diseasecortical surface area measurement

SOX5 ANO2 CNBD1 SUPT3H RPL37A SPTBN1 PICALM MEF2C FZD9 CADPS FBXO42 PRKAR2A SNTB1

2.26e-03134511513EFO_0010736
Diseasefacial asymmetry measurement

SOX5 CNBD1

2.47e-03191152EFO_0009751
DiseaseCardiomyopathies, Primary

PTGS2 AKT1 IL4

2.51e-03691153C0033141
DiseaseMyocardial Diseases, Secondary

PTGS2 AKT1 IL4

2.51e-03691153C0036529
DiseaseLupus Erythematosus, Systemic

PTGS2 PXK IL4

2.72e-03711153C0024141
Diseaseanti-Mullerian hormone measurement

MEF2C CDCA7

2.73e-03201152EFO_0004769
Diseaseunipolar depression, bipolar disorder, schizophrenia

TEX2 NCBP3

2.73e-03201152EFO_0003761, MONDO_0004985, MONDO_0005090
Diseasemelanoma

MYO1B XPA XPC PTGS2 AKT1

2.92e-032481155C0025202
Diseasein situ carcinoma (is_marker_for)

PTGS2 AKT1

3.01e-03211152DOID:8719 (is_marker_for)
Diseasestatus epilepticus (implicated_via_orthology)

GRIK1 PTGS2

3.01e-03211152DOID:1824 (implicated_via_orthology)
Diseasedepressive disorder (implicated_via_orthology)

NR3C1 RNF103

3.31e-03221152DOID:1596 (implicated_via_orthology)
Diseasefree androgen index

SOX5 DOK7 POR NR3C1 FZD9 SIDT2

3.52e-033741156EFO_0007005
Diseaseidiopathic pulmonary fibrosis (is_marker_for)

PTGS2 AKT1

3.61e-03231152DOID:0050156 (is_marker_for)
Diseaseepilepsy (implicated_via_orthology)

CHKA SBF1 UBE3A SBF2

3.86e-031631154DOID:1826 (implicated_via_orthology)
DiseaseLung Neoplasms

SLCO1B3 XPC SIDT2 AKT1 MAP2K7

3.87e-032651155C0024121

Protein segments in the cluster

PeptideGeneStartEntry
LVKEKATGRYYAMKI

AKT1

166

P31749
ATGRYYAMKILKKEV

AKT1

171

P31749
KEKEEMRKIIGRYGL

ABCF2

491

Q9UG63
LKEMKKGKEFYVIFD

GRIK1

216

P39086
KIPKEFIMKYKRGEI

ADAD1

81

Q96M93
VDVGKKKADISYMRF

CDADC1

446

Q9BWV3
EFLKIKVPTKKEMYE

ANO2

201

Q9NQ90
GKMQREKYLTILKAV

ASPM

2156

Q8IZT6
VDVKVVMLGKEYVGK

RAB24

6

Q969Q5
RKEMSLAKLGYFKEE

RAB3IP

461

Q96QF0
TFKTLERMKKYVFID

OVOS1

856

Q6IE37
LKTLIRMVKKTYRDF

CADPS

1286

Q9ULU8
MYVLDIKDTKEKGRV

FBXO42

646

Q6P3S6
RDKVLFYGRKIMRKV

PNPLA6

101

Q8IY17
VRLKKTDRIYAMKVV

PRKCI

271

P41743
TDRIYAMKVVKKELV

PRKCI

276

P41743
LKIYDRMKAKEFTGI

MDN1

1686

Q9NU22
KYRVKGLITKAEMLG

MAGEA11

236

P43364
EKMKKTGRNIIVFYG

POR

71

P16435
YIKKLMTKGRYSLDV

POR

661

P16435
ELKVKTVKYFKGLML

GNPDA1

246

P46926
EVVEIFKKQLMKFRY

SBF2

991

Q86WG5
KKLKFYLRDMTLSEG

NLRP10

26

Q86W26
EKKKVMGVLDIYGFE

MYO1A

371

Q9UBC5
DKKVEMLERKYGGSF

IQSEC2

331

Q5JU85
KMTVAIVKALYYLKE

MAP2K7

221

O14733
KVAIKKIMKRIFYSE

OR14C36

296

Q8NHC7
VFLKQIEKTMKRAYE

GXYLT2

416

A0PJZ3
MKKAIPKVRLETIYI

NCBP3

116

Q53F19
RLFKDGKMKYQIIDG

PTGS2

231

P35354
KEFGILAKTKYFQML

KNTC1

2136

P50748
FTKRKFGLMKKAYEL

MEF2C

21

Q06413
EKMRLDVNKIFYKDI

GABRB2

351

P47870
MTYIKELGKAIVKRE

NR3C1

691

P04150
FGKMETYIKLEKLGE

CDK17

186

Q00537
GKIMEVDYSVSKKLR

IGF2BP2

66

Q9Y6M1
FTKRKFGLMKKAYEL

MEF2A

21

Q02078
TRYGASLRKMVKKIE

RPL37A

16

P61513
FTKRKFGLMKKAYEL

MEF2B

21

Q02080
DMFILGYSLEVKIKV

OTULINL

301

Q9NUU6
FRKGIMKIMVYKIFR

MED18

136

Q9BUE0
ISYVFEGKMLEAKKL

SBF1

571

O95248
LEKLMVKIGVFSILY

FZD9

441

O00144
LAKVRMIKGEFYVIE

FMR1

81

Q06787
FLERLKTIMREKYSK

IL4

136

P05112
TYGTIVKMKRDDLKA

CIBAR1

101

A1XBS5
GIRKLYMKSLLKIFA

GPAT4

41

Q86UL3
DLYKFLTKRGEKMTR

EFCAB7

126

A8K855
GTMEKYLKEVLRIKF

CHKA

251

P35790
KAKLTEMRGIYAKVD

BCAS4

101

Q8TDM0
SGELVAIKRMKRKFY

MAK

26

P20794
ELRVKTVKYFKGLMH

GNPDA2

246

Q8TDQ7
KMLLKEYEERVIIKG

EFHB

631

Q8N7U6
MKIVDVIGEKIYKDG

PRKAR2A

271

P13861
LTKEDIIKFYKEMLA

IDE

931

P14735
LLMLVYKDKSERIKG

DOK7

36

Q18PE1
LGIIKAKMEEYFQKV

FAM186A

711

A6NE01
AFLVTLLIYRMKKKD

SDC3

401

O75056
LLIYRMKKKDEGSYT

SDC3

406

O75056
KVMLKEYSGRKIEVE

RNF103

186

O00237
KMLDYLKEKKDVGFF

RYR2

3776

Q92736
DRLSILLKGKMKVSY

BVES

171

Q8NE79
MLDKIMIIFRFIYGK

CUL4B

586

Q13620
MVKLQEIFKTFYLGK

CUL4B

701

Q13620
AGLEVTVDFKKLMKY

HELB

861

Q8NG08
FTKRKFGLMKKAYEL

MEF2D

21

Q14814
KLFGYEMAEFKVTIK

MRTO4

191

Q9UKD2
MVNEYKKILLLKGFE

MNDA

1

P41218
KMKLDYILGLKIEDF

RPS9

91

P46781
LITYLGAKMTRKYKE

AK9

1871

Q5TCS8
KRAGKEVLLEVKYMR

SNTB1

181

Q13884
FYIVEQRMKTKGEKV

HARS2

391

P49590
AFYIIMKLRSGERIK

SIDT2

731

Q8NBJ9
SGLDKKAKYILLMDI

TBX3

141

O15119
KEIKIYLGLSKMQRE

SMARCA1

411

P28370
LTGYKMKKRVGAIEE

TMCO4

251

Q5TGY1
GYQAKLFKGVLKERM

LIPI

301

Q6XZB0
MKAYRDTIKILQLGK

SHQ1

341

Q6PI26
LFKIDKEYLLKMATE

SAT1

156

P21673
VKEALIKELSMKIYF

OR5M8

296

Q8NGP6
IGKMRYVSVRDFKGK

SUB1

66

P53999
LGKYKDLLMKAETER

RACGAP1

51

Q9H0H5
LEFYKKDGLRKIQSM

ARHGAP44

501

Q17R89
QLGTTIYKEFEKRKM

SUCLG1

331

P53597
FSKRKTGIMKKAYEL

SRF

161

P11831
YFSKMKALAVEGKRI

SPTBN1

276

Q01082
SLEIYKKMFEVKRRE

CCDC134

31

Q9H6E4
NLKKFRYVKLISMET

CDCA7

16

Q9BWT1
VYMGKLKEKESFGEI

CNBD1

391

Q8NA66
VVLKEYLTMKAFVAK

CLCN1

201

P35523
ETMEVKTLGKLERYK

ATP11B

551

Q9Y2G3
KEGLDIYKKFLTRMT

PICALM

231

Q13492
IYELLFKEGVMVAKK

RPS10

11

P46783
KLFYKAIVRGKEMIR

TNRC18

2806

O15417
EIIKVYLKGRSGDKM

TUFT1

76

Q9NNX1
VYLDLTLDMALGKKK

MRPL1

121

Q9BYD6
GKIYFLLVRIKIKHM

VPS26B

191

Q4G0F5
EKDLMKAYLFKGNIL

TXNDC16

96

Q9P2K2
MKDLIKVAIKIGILY

TNFAIP8L3

166

Q5GJ75
KVMYKGLVPEDKTLR

UBFD1

126

O14562
VVYRKLMGKKGTFRD

UBE3A

636

Q05086
MFIRDYKSKIVKGID

SUPT3H

101

O75486
YGHIIKVFLMKDRKT

RBMXL3

31

Q8N7X1
RVSGLDKKAKYILLM

TBX2

141

Q13207
ALVLYIVFIFAMKKK

SLCO1B3

636

Q9NPD5
MEKGKYVGELRKALL

XRCC4

61

Q13426
EGYFTAIMLKKSRVK

TDP2

176

O95551
KLVETMYFKGIEAGK

TMEM135

356

Q86UB9
RMFNEKGTLKDLIYK

PXK

226

Q7Z7A4
LRYEIKQIKMFKGFE

TIMP4

71

Q99727
YFSKMKVLAVEGKRV

SPTB

276

P11277
RLDFELGKMIKQSYK

PKD2L2

506

Q9NZM6
EMVGIIYKPKTKETR

SNRNP200

96

O75643
GDMKLYLKLQIVKRS

XPA

176

P23025
RLFSKVLVTIKKVYM

ZNF879

136

B4DU55
VLVTIKKVYMKERSF

ZNF879

141

B4DU55
KKVYMKERSFKGVEF

ZNF879

146

B4DU55
ILRKMGKSVDYFLSI

SLC35G1

241

Q2M3R5
DGKKLRIGEYKAIMR

SOX5

636

P35711
KIKLEFETYLRRAMK

XPC

181

Q01831
KIMRFVDKITKSKYF

TEX2

986

Q8IWB9
GLKGMLIQFRDLKKY

SLC26A7

416

Q8TE54
MVGSKLKVIFLENYR

PYGL

636

P06737
KQRKLNFLEIYGEKM

VPS54

391

Q9P1Q0
TKVRKKVMGVLDIYG

MYO1B

376

O43795
AELSVYGKLRKVAKM

NADSYN1

596

Q6IA69
IEELSKKDKGIYRAM

MYOM3

1176

Q5VTT5
SKMLSGREYKKLFEE

NEBL

296

O76041