Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessSA node cell to atrial cardiac muscle cell communication

GJC1 HCN4

3.09e-0511162GO:0086070
Pubmed

Connexin 30 is expressed in the mouse sino-atrial node and modulates heart rate.

GJC1 HCN4

2.25e-06517219679680
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

HCN4 STOX2 TAF15 PKP4 PBRM1 TCF20

4.23e-0696317628671696
Pubmed

Rescue of deficits by Brwd1 copy number restoration in the Ts65Dn mouse model of Down syndrome.

SS18L1 PBRM1

2.04e-051417236289231
Pubmed

PBAF Subunit Pbrm1 Selectively Influences the Transition from Progenitors to Pre-Myelinating Cells during Oligodendrocyte Development.

MCM2 PBRM1

2.35e-051517237371026
Pubmed

Kinetic analysis of npBAF to nBAF switching reveals exchange of SS18 with CREST and integration with neural developmental pathways.

SS18L1 PBRM1

2.35e-051517223785148
Pubmed

Role of the Pbrm1 subunit and the PBAF complex in Schwann cell development.

MCM2 PBRM1

3.83e-051917235173232
Pubmed

GATA6 is a regulator of sinus node development and heart rhythm.

GJC1 HCN4

4.25e-052017233443158
Pubmed

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.

PBRM1 ADIPOQ

4.70e-052117222479202
Pubmed

TTF-1/NKX2-1 binds to DDB1 and confers replication stress resistance to lung adenocarcinomas.

MCM2 TAF15 TCF20

5.32e-0515217328192407
Pubmed

FET family fusion oncoproteins target the SWI/SNF chromatin remodeling complex.

TAF15 PBRM1

5.66e-052317230962207
Pubmed

An embryonic stem cell chromatin remodeling complex, esBAF, is essential for embryonic stem cell self-renewal and pluripotency.

SS18L1 PBRM1

9.06e-052917219279220
Pubmed

High-throughput analyses of hnRNP H1 dissects its multi-functional aspect.

B4GALNT2 TAF15 PKP4 SS18L1 TCF20

9.95e-05102117526760575
Pubmed

Microarray analysis of the Df1 mouse model of the 22q11 deletion syndrome.

GJC1 TCF20

1.04e-043117215778864
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

CPA4 MCM2 PKP4 ASAP1 TCF20

3.70e-04135317529467282
Pubmed

Loss of BAF (mSWI/SNF) Complexes Causes Global Transcriptional and Chromatin State Changes in Forebrain Development.

SS18L1 PBRM1

4.59e-046517226655900
CytobandEnsembl 112 genes in cytogenetic band chr17q21

GJC1 B4GALNT2

1.30e-02473172chr17q21
DiseaseBMI-adjusted adiponectin measurement

PBRM1 ADIPOQ

2.88e-0515162EFO_0007737
DiseaseCrohn's disease (is_marker_for)

PBRM1 ADIPOQ

1.11e-0429162DOID:8778 (is_marker_for)
DiseaseR-6-hydroxywarfarin to R-warfarin ratio measurement

B4GALNT2 STOX2

1.48e-03106162EFO_0803333
DiseasePapillary Renal Cell Carcinoma

PBRM1 ADIPOQ

2.15e-03128162C1306837
DiseaseRenal Cell Carcinoma

PBRM1 ADIPOQ

2.15e-03128162C0007134
DiseaseSarcomatoid Renal Cell Carcinoma

PBRM1 ADIPOQ

2.15e-03128162C1266043
DiseaseChromophobe Renal Cell Carcinoma

PBRM1 ADIPOQ

2.15e-03128162C1266042
DiseaseCollecting Duct Carcinoma of the Kidney

PBRM1 ADIPOQ

2.15e-03128162C1266044
Diseaseadiponectin measurement

PBRM1 ADIPOQ

2.79e-03146162EFO_0004502
DiseaseConventional (Clear Cell) Renal Cell Carcinoma

PBRM1 ADIPOQ

2.86e-03148162C0279702
Diseaseautism spectrum disorder (implicated_via_orthology)

PKP4 TCF20

3.02e-03152162DOID:0060041 (implicated_via_orthology)
Diseaseautism spectrum disorder

PKP4 ASAP1

3.17e-03156162EFO_0003756
DiseaseHypertensive disease

GJC1 ADIPOQ

4.66e-03190162C0020538

Protein segments in the cluster

PeptideGeneStartEntry
GYQEAGSFHNSQNVS

PKP4

156

Q99569
EKHSSSYNQGGYNQD

SYNPR

216

Q8TBG9
EQGGYNFQDAYGQSD

B4GALNT2

146

Q8NHY0
YDQYQENNVDQASGS

ADIPOQ

186

Q15848
GQQDSYDQQSGYDQH

TAF15

111

Q92804
YDQQSGYDQHQGSYD

TAF15

116

Q92804
GYDQHQGSYDEQSNY

TAF15

121

Q92804
QGSYDEQSNYDQQHD

TAF15

126

Q92804
GIYHNNYDGSLNTAN

MCM2

416

P49736
NARHYNEEGSQVYND

PBRM1

596

Q86U86
NGQIHYDHQNDGASQ

LMAN1

171

P49257
QHDLNSGVFNYQENE

HCN4

726

Q9Y3Q4
ANTAQEQQYGSHEEN

GJC1

316

P36383
QHNEGQERSSNNFNY

CPA4

106

Q9UI42
IYNSGQDHVQNEENY

ASAP1

81

Q9ULH1
HYYEGGNSQYSQQQA

SS18L1

301

O75177
QESGGNQEASFDYYN

STOX2

761

Q9P2F5
EQSSYHGNQQSYPQE

TCF20

6

Q9UGU0
QDQSYHYGQTDRQGQ

RPTN

301

Q6XPR3
QCYHYDQTNRQGQGS

RPTN

351

Q6XPR3
DTHGVEAFQSGQNNY

ZNF17

176

P17021