Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	translation elongation factor activity	EIF5AL1 EIF5A EIF5A2	6.23e-05	20	78	3	GO:0003746
GeneOntologyMolecularFunction	aliphatic amine oxidase activity	AOC2 AOC3	8.99e-05	4	78	2	GO:0052595
GeneOntologyMolecularFunction	guanyl-nucleotide exchange factor activity	DOCK3 RAPGEF6 TRIO FARP1 HERC2 PREX1	2.88e-04	231	78	6	GO:0005085
GeneOntologyMolecularFunction	primary methylamine oxidase activity	AOC2 AOC3	5.33e-04	9	78	2	GO:0008131
GeneOntologyBiologicalProcess	positive regulation of translational termination	EIF5AL1 EIF5A EIF5A2	2.00e-07	4	77	3	GO:0045905
GeneOntologyBiologicalProcess	positive regulation of translational elongation	EIF5AL1 EIF5A EIF5A2	4.98e-07	5	77	3	GO:0045901
GeneOntologyBiologicalProcess	regulation of translational termination	EIF5AL1 EIF5A EIF5A2	4.13e-06	9	77	3	GO:0006449
GeneOntologyBiologicalProcess	regulation of translational elongation	EIF5AL1 EIF5A EIF5A2	1.77e-05	14	77	3	GO:0006448
GeneOntologyBiologicalProcess	translational termination	EIF5AL1 EIF5A EIF5A2	3.28e-05	17	77	3	GO:0006415
Domain	IF5A_HYPUSINE	EIF5AL1 EIF5A EIF5A2	7.28e-08	3	79	3	PS00302
Domain	Transl_elong_IF5A_C	EIF5AL1 EIF5A EIF5A2	7.28e-08	3	79	3	IPR020189
Domain	Transl_elong_IF5A	EIF5AL1 EIF5A EIF5A2	7.28e-08	3	79	3	IPR001884
Domain	eIF-5a	EIF5AL1 EIF5A EIF5A2	7.28e-08	3	79	3	PF01287
Domain	Trans_elong_IF5A_hypusine_site	EIF5AL1 EIF5A EIF5A2	7.28e-08	3	79	3	IPR019769
Domain	eIF-5a	EIF5AL1 EIF5A EIF5A2	7.28e-08	3	79	3	SM01376
Domain	Rib_L2_dom2	EIF5AL1 EIF5A EIF5A2 HERC2	8.67e-07	18	79	4	IPR014722
Domain	-	EIF5AL1 EIF5A EIF5A2 HERC2	8.67e-07	18	79	4	2.30.30.30
Domain	NA-bd_OB-fold	CSDE1 EIF5AL1 EIF5A EIF5A2 MCM2	2.67e-05	83	79	5	IPR012340
Domain	Translation_prot_SH3-like	EIF5AL1 EIF5A EIF5A2	4.75e-05	17	79	3	IPR008991
Domain	-	AOC2 AOC3	5.29e-05	3	79	2	2.70.98.20
Domain	Cu_amine_oxidase_N3	AOC2 AOC3	5.29e-05	3	79	2	IPR015802
Domain	Cu_amine_oxidase_N2	AOC2 AOC3	5.29e-05	3	79	2	IPR015800
Domain	Cu_amine_oxidN2	AOC2 AOC3	5.29e-05	3	79	2	PF02727
Domain	Cu_amine_oxidN3	AOC2 AOC3	5.29e-05	3	79	2	PF02728
Domain	Cu_amine_oxidase_N-reg	AOC2 AOC3	5.29e-05	3	79	2	IPR016182
Domain	Cu_amine_oxid	AOC2 AOC3	5.29e-05	3	79	2	PF01179
Domain	Cu_amine_oxidase_C	AOC2 AOC3	5.29e-05	3	79	2	IPR015798
Domain	COPPER_AMINE_OXID_1	AOC2 AOC3	5.29e-05	3	79	2	PS01164
Domain	COPPER_AMINE_OXID_2	AOC2 AOC3	5.29e-05	3	79	2	PS01165
Domain	Cu_amine_oxidase	AOC2 AOC3	1.05e-04	4	79	2	IPR000269
Domain	F5_F8_type_C	CNTNAP3B CNTNAP3 BTBD9	1.38e-04	24	79	3	PF00754
Domain	FA58C	CNTNAP3B CNTNAP3 BTBD9	1.38e-04	24	79	3	IPR000421
Domain	-	ZNF131 ZNF777 ZFAT ZBTB39 REST ZNF227 ZNF468 PRDM15 ZNF415 ZFX	5.66e-04	679	79	10	3.30.160.60
Domain	GDS_CDC24_CS	TRIO FARP1 PREX1	5.96e-04	39	79	3	IPR001331
Domain	zf-C2H2	ZNF131 ZNF777 ZFAT ZBTB39 REST ZNF227 ZNF468 PRDM15 ZNF415 ZFX	6.63e-04	693	79	10	PF00096
Domain	Znf_C2H2/integrase_DNA-bd	ZNF131 ZNF777 ZFAT ZBTB39 REST ZNF227 ZNF468 PRDM15 ZNF415 ZFX	6.70e-04	694	79	10	IPR013087
Domain	Galactose-bd-like	CNTNAP3B CNTNAP3 HERC2 BTBD9	6.77e-04	94	79	4	IPR008979
Domain	KOW	EIF5A EIF5A2	9.48e-04	11	79	2	IPR005824
Domain	KOW	EIF5A EIF5A2	9.48e-04	11	79	2	PF00467
Domain	FERM-adjacent	FARP1 EPB41L4A	1.34e-03	13	79	2	IPR014847
Domain	FA	FARP1 EPB41L4A	1.34e-03	13	79	2	SM01195
Domain	FA	FARP1 EPB41L4A	1.34e-03	13	79	2	PF08736
Domain	ZINC_FINGER_C2H2_2	ZNF131 ZNF777 ZFAT ZBTB39 REST ZNF227 ZNF468 PRDM15 ZNF415 ZFX	1.55e-03	775	79	10	PS50157
Domain	PIN_domain-like	FAM120A MARF1	1.56e-03	14	79	2	IPR029060
Domain	ZINC_FINGER_C2H2_1	ZNF131 ZNF777 ZFAT ZBTB39 REST ZNF227 ZNF468 PRDM15 ZNF415 ZFX	1.58e-03	777	79	10	PS00028
Domain	Znf_C2H2-like	ZNF131 ZNF777 ZFAT ZBTB39 REST ZNF227 ZNF468 PRDM15 ZNF415 ZFX	1.88e-03	796	79	10	IPR015880
Domain	-	PIK3CG TRRAP	2.04e-03	16	79	2	1.10.1070.11
Domain	PI3Kc	PIK3CG TRRAP	2.04e-03	16	79	2	SM00146
Domain	Znf_C2H2	ZNF131 ZNF777 ZFAT ZBTB39 REST ZNF227 ZNF468 PRDM15 ZNF415 ZFX	2.04e-03	805	79	10	IPR007087
Domain	Kinase-like_dom	TRIO PIK3CG STK32B TBCK RIPK4 MERTK TRRAP DYRK2	2.05e-03	542	79	8	IPR011009
Domain	ZnF_C2H2	ZNF131 ZNF777 ZFAT ZBTB39 REST ZNF227 ZNF468 PRDM15 ZNF415 ZFX	2.10e-03	808	79	10	SM00355
Domain	DH_1	TRIO FARP1 PREX1	2.41e-03	63	79	3	PS00741
Domain	PI3/4_kinase_cat_dom	PIK3CG TRRAP	2.59e-03	18	79	2	IPR000403
Domain	ZZ	HERC2 CREBBP	2.59e-03	18	79	2	PF00569
Domain	PI3_PI4_kinase	PIK3CG TRRAP	2.59e-03	18	79	2	PF00454
Domain	PI3_4_KINASE_3	PIK3CG TRRAP	2.59e-03	18	79	2	PS50290
Domain	ZF_ZZ_2	HERC2 CREBBP	2.59e-03	18	79	2	PS50135
Domain	PI3_4_KINASE_1	PIK3CG TRRAP	2.59e-03	18	79	2	PS00915
Domain	PI3_4_KINASE_2	PIK3CG TRRAP	2.59e-03	18	79	2	PS00916
Domain	ZF_ZZ_1	HERC2 CREBBP	2.59e-03	18	79	2	PS01357
Domain	Znf_ZZ	HERC2 CREBBP	2.88e-03	19	79	2	IPR000433
Domain	ZnF_ZZ	HERC2 CREBBP	2.88e-03	19	79	2	SM00291
Domain	RhoGEF	TRIO FARP1 PREX1	3.00e-03	68	79	3	SM00325
Domain	RhoGEF	TRIO FARP1 PREX1	3.25e-03	70	79	3	PF00621
Domain	DH_2	TRIO FARP1 PREX1	3.25e-03	70	79	3	PS50010
Domain	DH-domain	TRIO FARP1 PREX1	3.39e-03	71	79	3	IPR000219
Domain	-	TRIO FARP1 PREX1	3.39e-03	71	79	3	1.20.900.10
Domain	FA58C	CNTNAP3B CNTNAP3	3.52e-03	21	79	2	SM00231
Domain	Ez/rad/moesin-like	FARP1 EPB41L4A	3.52e-03	21	79	2	IPR000798
Domain	FA58C_3	CNTNAP3B CNTNAP3	3.52e-03	21	79	2	PS50022
Domain	FA58C_1	CNTNAP3B CNTNAP3	3.52e-03	21	79	2	PS01285
Domain	FA58C_2	CNTNAP3B CNTNAP3	3.52e-03	21	79	2	PS01286
Domain	-	CNTNAP3 HERC2 BTBD9	3.66e-03	73	79	3	2.60.120.260
Domain	Spectrin	TRIO SYNE2	4.22e-03	23	79	2	PF00435
Pathway	REACTOME_HYPUSINE_SYNTHESIS_FROM_EIF5A_LYSINE	EIF5AL1 EIF5A EIF5A2	9.74e-07	5	66	3	MM14823
Pubmed	Human eIF5A2 on chromosome 3q25-q27 is a phylogenetically conserved vertebrate variant of eukaryotic translation initiation factor 5A with tissue-specific expression.	EIF5AL1 EIF5A EIF5A2	1.17e-08	3	80	3	11161802
Pubmed	New K50R mutant mouse models reveal impaired hypusination of eif5a2 with alterations in cell metabolite landscape.	EIF5AL1 EIF5A EIF5A2	1.17e-08	3	80	3	36848144
Pubmed	Differential expression of eIF5A-1 and eIF5A-2 in human cancer cells.	EIF5AL1 EIF5A EIF5A2	1.17e-08	3	80	3	16519677
Pubmed	Biological Relevance and Therapeutic Potential of the Hypusine Modification System.	EIF5AL1 EIF5A EIF5A2	1.17e-07	5	80	3	26037925
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	DOCK3 CSDE1 SEMA4D DCHS2 FAM120A TRIO GLS RIPK4 ZNF227 HERC2 MERTK UROD CREBBP PREX1	1.27e-06	1285	80	14	35914814
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	CSDE1 SEMA4D PTPRB FAM120A TRIO FARP1 TBCK DAB1 BTBD9 TEP1 TRRAP PRDM15 CREBBP THRAP3 PLEKHM1	1.34e-06	1489	80	15	28611215
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	DOCK3 ABCC3 RAPGEF6 TRIO AOC2 PCYT2 HERC2 TEP1 TRRAP PREX1 AP3D1 PLEKHM1 TOP3A	1.37e-06	1105	80	13	35748872
Pubmed	Scanning the human proteome for calmodulin-binding proteins.	DOCK3 SYNE2 PAM HERC2 NEB	2.39e-06	92	80	5	15840729
Pubmed	Identification of Novel Nuclear Factor of Activated T Cell (NFAT)-associated Proteins in T Cells.	ZNF131 ALDH18A1 MCM2 TRRAP PRDM15 CREBBP	3.63e-06	178	80	6	27637333
Pubmed	Peptide selectivity discriminates NK cells from KIR2DL2- and KIR2DL3-positive individuals.	KIR2DL2 KIR2DL3	5.23e-06	2	80	2	25359276
Pubmed	Comparison of Human Eukaryotic Translation Initiation Factors 5A1 and 5AL1: Identification of Amino Acid Residues Important for EIF5A1 Lysine 50 Hypusination and Its Protein Stability.	EIF5AL1 EIF5A	5.23e-06	2	80	2	37047039
Pubmed	Allelic polymorphism of KIR2DL2/2DL3 in a southern Chinese population.	KIR2DL2 KIR2DL3	5.23e-06	2	80	2	26423800
Pubmed	The critical role of ASD-related gene CNTNAP3 in regulating synaptic development and social behavior in mice.	CNTNAP3B CNTNAP3	5.23e-06	2	80	2	31150793
Pubmed	Structural plasticity of KIR2DL2 and KIR2DL3 enables altered docking geometries atop HLA-C.	KIR2DL2 KIR2DL3	5.23e-06	2	80	2	33846289
Pubmed	Identification of four novel KIR2DL2 alleles and two novel KIR2DL3 alleles in an East African population.	KIR2DL2 KIR2DL3	5.23e-06	2	80	2	20875478
Pubmed	Polyamines and eIF5A Hypusination Modulate Mitochondrial Respiration and Macrophage Activation.	EIF5AL1 EIF5A	5.23e-06	2	80	2	31130465
Pubmed	Independent roles of eIF5A and polyamines in cell proliferation.	EIF5AL1 EIF5A	5.23e-06	2	80	2	15377278
Pubmed	Sequence determination and cDNA cloning of eukaryotic initiation factor 4D, the hypusine-containing protein.	EIF5AL1 EIF5A	5.23e-06	2	80	2	2492279
Pubmed	The N-terminal region of eukaryotic translation initiation factor 5A signals to nuclear localization of the protein.	EIF5AL1 EIF5A	5.23e-06	2	80	2	17707773
Pubmed	Proteomic analysis of ubiquitin-proteasome effects: insight into the function of eukaryotic initiation factor 5A.	EIF5AL1 EIF5A	5.23e-06	2	80	2	12894223
Pubmed	Caspr3-Deficient Mice Exhibit Low Motor Learning during the Early Phase of the Accelerated Rotarod Task.	CNTNAP3B CNTNAP3	5.23e-06	2	80	2	26807827
Pubmed	The unique substrate specificity of human AOC2, a semicarbazide-sensitive amine oxidase.	AOC2 AOC3	5.23e-06	2	80	2	19588076
Pubmed	Genetic polymorphism of NK receptors and their ligands in melanoma patients: prevalence of inhibitory over activating signals.	KIR2DL2 KIR2DL3	5.23e-06	2	80	2	15248031
Pubmed	Allelic variation in KIR2DL3 generates a KIR2DL2-like receptor with increased binding to its HLA-C ligand.	KIR2DL2 KIR2DL3	5.23e-06	2	80	2	23686481
Pubmed	Targeted inhibition of eIF5Ahpu suppresses tumor growth and polarization of M2-like tumor-associated macrophages in oral cancer.	EIF5AL1 EIF5A	5.23e-06	2	80	2	37653021
Pubmed	Identification of a new member of the human eIF-5A gene family.	EIF5AL1 EIF5A	5.23e-06	2	80	2	7622067
Pubmed	Eukaryotic initiation factor 5A is a cellular target of the human immunodeficiency virus type 1 Rev activation domain mediating trans-activation.	EIF5AL1 EIF5A	5.23e-06	2	80	2	8253832
Pubmed	Differential association of gene content polymorphisms of killer cell immunoglobulin-like receptors with placental malaria in HIV- and HIV+ mothers.	KIR2DL2 KIR2DL3	5.23e-06	2	80	2	22715396
Pubmed	Anatomical distribution of primary amine oxidase activity in four adipose depots and plasma of severely obese women with or without a dysmetabolic profile.	AOC2 AOC3	5.23e-06	2	80	2	27766585
Pubmed	KIR2DL2/2DL3-E(35) alleles are functionally stronger than -Q(35) alleles.	KIR2DL2 KIR2DL3	5.23e-06	2	80	2	27030405
Pubmed	Eukaryotic initiation factor 4D. Purification from human red blood cells and the sequence of amino acids around its single hypusine residue.	EIF5AL1 EIF5A	5.23e-06	2	80	2	3095320
Pubmed	Exosomal EIF5A derived from Lewis lung carcinoma induced adipocyte wasting in cancer cachexia.	EIF5AL1 EIF5A	5.23e-06	2	80	2	37743008
Pubmed	Homology modelling of the human eukaryotic initiation factor 5A (eIF-5A).	EIF5AL1 EIF5A	5.23e-06	2	80	2	11742107
Pubmed	The unique hypusine modification of eIF5A promotes islet beta cell inflammation and dysfunction in mice.	EIF5AL1 EIF5A	5.23e-06	2	80	2	20501948
Pubmed	Proteomic and Interactome Approaches Reveal PAK4, PHB-2, and 14-3-3η as Targets of Overactivated Cdc42 in Cellular Responses to Genomic Instability.	TRIO GLS ALDH18A1 TRRAP ZNF415 AP3D1	1.38e-05	225	80	6	31478661
Pubmed	Deoxyhypusine synthase mutations alter the post-translational modification of eukaryotic initiation factor 5A resulting in impaired human and mouse neural homeostasis.	EIF5AL1 EIF5A	1.57e-05	3	80	2	37333770
Pubmed	Killer immunoglobulin receptor genes and their HLA-C ligand are associated with Type 1 diabetes in an Eastern Indian population.	KIR2DL2 KIR2DL3	1.57e-05	3	80	2	26031759
Pubmed	Combined inhibition of polyamine metabolism and eIF5A hypusination suppresses colorectal cancer growth through a converging effect on MYC translation.	EIF5AL1 EIF5A	1.57e-05	3	80	2	36893894
Pubmed	Haplotypes spanning SPEC2, PDZ-GEF2 and ACSL6 genes are associated with schizophrenia.	ACSL6 RAPGEF6	1.57e-05	3	80	2	17030554
Pubmed	Killer Immunoglobulin-Like Receptor 2DS2 (KIR2DS2), KIR2DL2-HLA-C1, and KIR2DL3 as Genetic Markers for Stratifying the Risk of Cytomegalovirus Infection in Kidney Transplant Recipients.	KIR2DL2 KIR2DL3	1.57e-05	3	80	2	30696053
Pubmed	Association of haplotypes spanning PDZ-GEF2, LOC728637 and ACSL6 with schizophrenia in Han Chinese.	ACSL6 RAPGEF6	1.57e-05	3	80	2	18718982
Pubmed	Increased Susceptibility of the CD57- NK Cells Expressing KIR2DL2/3 and NKG2C to iCasp9 Gene Retroviral Transduction and the Relationships with Proliferative Potential, Activation Degree, and Death Induction Response.	KIR2DL2 KIR2DL3	1.57e-05	3	80	2	34948123
Pubmed	Essential role of eIF5A-1 and deoxyhypusine synthase in mouse embryonic development.	EIF5AL1 EIF5A	1.57e-05	3	80	2	21850436
Pubmed	Natural killer cell receptor variants and chronic hepatitis B virus infection in the Vietnamese population.	KIR2DL2 KIR2DL3	1.57e-05	3	80	2	32422377
Pubmed	Susceptibility to Crohn's disease is mediated by KIR2DL2/KIR2DL3 heterozygosity and the HLA-C ligand.	KIR2DL2 KIR2DL3	1.57e-05	3	80	2	19789864
Pubmed	Mutation at positively selected positions in the binding site for HLA-C shows that KIR2DL1 is a more refined but less adaptable NK cell receptor than KIR2DL3.	KIR2DL2 KIR2DL3	1.57e-05	3	80	2	22772445
Pubmed	Comparison of killer Ig-like receptor genotyping and phenotyping for selection of allogeneic blood stem cell donors.	KIR2DL2 KIR2DL3	1.57e-05	3	80	2	15879158
Pubmed	Implication of HLA-C and KIR alleles in human papillomavirus infection and associated cervical lesions.	KIR2DL2 KIR2DL3	1.57e-05	3	80	2	25188020
Pubmed	Characterization of AOC2 gene encoding a copper-binding amine oxidase expressed specifically in retina.	AOC2 AOC3	1.57e-05	3	80	2	14585497
Pubmed	Klf5 down-regulation induces vascular senescence through eIF5a depletion and mitochondrial fission.	EIF5AL1 EIF5A	1.57e-05	3	80	2	32817651
Pubmed	Associations of killer cell immunoglobulin- like receptor genes with rheumatoid arthritis.	KIR2DL2 KIR2DL3	1.57e-05	3	80	2	22960345
Pubmed	Identification and characterization of eukaryotic initiation factor 5A-2.	EIF5A EIF5A2	1.57e-05	3	80	2	14622290
Pubmed	The role of polyamines in supporting growth of mammalian cells is mediated through their requirement for translation initiation and elongation.	EIF5AL1 EIF5A	1.57e-05	3	80	2	20181941
Pubmed	Genetic risk for co-occurrence of type 1 diabetes and celiac disease is modified by HLA-C and killer immunoglobulin-like receptors.	KIR2DL2 KIR2DL3	1.57e-05	3	80	2	25329633
Pubmed	Evidences of a role for eukaryotic translation initiation factor 5A (eIF5A) in mouse embryogenesis and cell differentiation.	EIF5AL1 EIF5A	1.57e-05	3	80	2	20458750
Pubmed	Imputation of KIR Types from SNP Variation Data.	KIR2DL2 KIR2DL3	1.57e-05	3	80	2	26430804
Pubmed	Conjunctival scarring in trachoma is associated with the HLA-C ligand of KIR and is exacerbated by heterozygosity at KIR2DL2/KIR2DL3.	KIR2DL2 KIR2DL3	1.57e-05	3	80	2	24651768
Pubmed	Subcellular localization of the hypusine-containing eukaryotic initiation factor 5A by immunofluorescent staining and green fluorescent protein tagging.	EIF5AL1 EIF5A	1.57e-05	3	80	2	12210765
Pubmed	[Effect of demethylation treatment on the expression of inhibitory receptor KIR gene in NK-92MI cell line].	KIR2DL2 KIR2DL3	1.57e-05	3	80	2	19549382
Pubmed	Cutting edge: selective expression of inhibitory or activating killer cell Ig-like receptors in circulating CD4+ T lymphocytes.	KIR2DL2 KIR2DL3	1.57e-05	3	80	2	18292496
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	ABCC3 AZIN2 GLS SYNE2 CEP295 ZNF227 NEB CREBBP PREX1	1.62e-05	638	80	9	31182584
Pubmed	FoxP1 orchestration of ASD-relevant signaling pathways in the striatum.	CNTNAP3B DPP10 CNTNAP3	1.75e-05	22	80	3	26494785
Pubmed	MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.	CSDE1 SEMA4D TRIO SYNE2 DAB1 AP3D1 THRAP3	1.93e-05	358	80	7	32460013
Pubmed	B-lymphoma cells escape rituximab-triggered elimination by NK cells through increased HLA class I expression.	KIR2DL2 KIR2DL3	3.13e-05	4	80	2	20056126
Pubmed	GRK2 mediates TCR-induced transactivation of CXCR4 and TCR-CXCR4 complex formation that drives PI3Kγ/PREX1 signaling and T cell cytokine secretion.	PIK3CG PREX1	3.13e-05	4	80	2	30018141
Pubmed	HLA-C and KIR genes in hepatitis C virus infection.	KIR2DL2 KIR2DL3	3.13e-05	4	80	2	16571411
Pubmed	Cell-type-specific function of BCL9 involves a transcriptional activation domain that synergizes with beta-catenin.	TRRAP CREBBP	3.13e-05	4	80	2	18347063
Pubmed	Killer Ig-like receptor (KIR) genotype and HLA ligand combinations in ulcerative colitis susceptibility.	KIR2DL2 KIR2DL3	3.13e-05	4	80	2	16929347
Pubmed	The genomic structure encoding human initiation factor eIF-5A.	EIF5AL1 EIF5A	3.13e-05	4	80	2	7545941
Pubmed	The eukaryotic cofactor for the human immunodeficiency virus type 1 (HIV-1) rev protein, eIF-5A, maps to chromosome 17p12-p13: three eIF-5A pseudogenes map to 10q23.3, 17q25, and 19q13.2.	EIF5AL1 EIF5A	3.13e-05	4	80	2	7759117
Pubmed	KIR/HLA ligand incompatibility in kidney transplantation.	KIR2DL2 KIR2DL3	3.13e-05	4	80	2	18091530
Pubmed	High-throughput genotyping of KIR2DL2/L3, KIR3DL1/S1, and their HLA class I ligands using real-time PCR.	KIR2DL2 KIR2DL3	3.13e-05	4	80	2	19522772
Pubmed	[Analysis of HLA-Cw, KIR2D genetic variations in 2 Chinese populations].	KIR2DL2 KIR2DL3	3.13e-05	4	80	2	18543232
Pubmed	Expression of eukaryotic initiation factor 5A and hypusine forming enzymes in glioblastoma patient samples: implications for new targeted therapies.	EIF5A EIF5A2	3.13e-05	4	80	2	22927971
Pubmed	Oligoclonal band phenotypes in MS differ in their HLA class II association, while specific KIR ligands at HLA class I show association to MS in general.	KIR2DL2 KIR2DL3	3.13e-05	4	80	2	25037176
Pubmed	[Distribution of immunoglobulin like receptor gene in Han population in China and the impact thereof on the HLA-identical sibling hematopoietic stem cell transplantation].	KIR2DL2 KIR2DL3	3.13e-05	4	80	2	18269867
Pubmed	HERC2 Interacts with Claspin and regulates DNA origin firing and replication fork progression.	MCM2 HERC2	3.13e-05	4	80	2	21775519
Pubmed	Investigation of activating and inhibitory killer cell immunoglobulin-like receptors and their putative ligands in type 1 diabetes (T1D).	KIR2DL2 KIR2DL3	3.13e-05	4	80	2	26542066
Pubmed	DHPS-dependent hypusination of eIF5A1/2 is necessary for TGFβ/fibronectin-induced breast cancer metastasis and associates with prognostically unfavorable genomic alterations in TP53.	EIF5A EIF5A2	3.13e-05	4	80	2	31558321
Pubmed	The post-translational synthesis of a polyamine-derived amino acid, hypusine, in the eukaryotic translation initiation factor 5A (eIF5A).	EIF5A EIF5A2	3.13e-05	4	80	2	16452303
Pubmed	Protective KIR-HLA interactions for HCV infection in intravenous drug users.	KIR2DL2 KIR2DL3	3.13e-05	4	80	2	19552960
Pubmed	Activating killer cell immunoglobulin-like receptor gene KIR2DS1 is associated with psoriatic arthritis.	KIR2DL2 KIR2DL3	5.20e-05	5	80	2	16112031
Pubmed	Role of the hepatocyte nuclear factor-1beta (HNF-1beta) C-terminal domain in Pkhd1 (ARPKD) gene transcription and renal cystogenesis.	PKHD1 CREBBP	5.20e-05	5	80	2	15647252
Pubmed	Analysis of candidate genes on chromosome 19 in coeliac disease: an association study of the KIR and LILR gene clusters.	KIR2DL2 KIR2DL3	5.20e-05	5	80	2	12121272
Pubmed	Association of killer cell immunoglobulin-like receptor genotypes with vascular arterial events and anticardiolipin antibodies in patients with lupus.	KIR2DL2 KIR2DL3	5.20e-05	5	80	2	18755860
Pubmed	Synergistic polymorphism at two positions distal to the ligand-binding site makes KIR2DL2 a stronger receptor for HLA-C than KIR2DL3.	KIR2DL2 KIR2DL3	5.20e-05	5	80	2	18322206
Pubmed	Neuron-specific ablation of eIF5A or deoxyhypusine synthase leads to impairments in growth, viability, neurodevelopment, and cognitive functions in mice.	EIF5AL1 EIF5A	5.20e-05	5	80	2	34688659
Pubmed	Associations of killer cell immunoglobulin-like receptor genes with complications of rheumatoid arthritis.	KIR2DL2 KIR2DL3	7.79e-05	6	80	2	17882223
Pubmed	In trans neuregulin3-Caspr3 interaction controls DA axonal bassoon cluster development.	CNTNAP3B CNTNAP3	7.79e-05	6	80	2	34143959
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	DOCK3 ZBTB39 HERC2 PLEKHM1	1.00e-04	104	80	4	9205841
Pubmed	Human ING1 proteins differentially regulate histone acetylation.	TRRAP CREBBP	1.09e-04	7	80	2	12015309
Pubmed	Ts65Dn -- localization of the translocation breakpoint and trisomic gene content in a mouse model for Down syndrome.	RIPK4 PRDM15	1.09e-04	7	80	2	11528125
Pubmed	Identification of seventeen novel KIR variants: fourteen of them from two non-Caucasian donors.	KIR2DL2 KIR2DL3	1.09e-04	7	80	2	11169255
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	CSDE1 TGFBI RAPGEF6 FAM120A MARF1 PAM AP3D1 TOP3A	1.27e-04	650	80	8	38777146
Pubmed	KIR haplotype content at the allele level in 77 Northern Irish families.	KIR2DL2 KIR2DL3	1.45e-04	8	80	2	17200871
Pubmed	P-Rex1 directly activates RhoG to regulate GPCR-driven Rac signalling and actin polarity in neutrophils.	PIK3CG PREX1	1.45e-04	8	80	2	24659802
Pubmed	Genotypes of NK cell KIR receptors, their ligands, and Fcγ receptors in the response of neuroblastoma patients to Hu14.18-IL2 immunotherapy.	KIR2DL2 KIR2DL3	1.45e-04	8	80	2	20935224
Pubmed	A population-based cohort study of KIR genes and genotypes in relation to cervical intraepithelial neoplasia.	KIR2DL2 KIR2DL3	1.45e-04	8	80	2	15730517
Pubmed	NullHap--a versatile application to estimate haplotype frequencies from unphased genotypes in the presence of null alleles.	KIR2DL2 KIR2DL3	1.45e-04	8	80	2	18681957
Pubmed	Interaction between interleukin 3 and dystrobrevin-binding protein 1 in schizophrenia.	ACSL6 RAPGEF6	1.45e-04	8	80	2	18804346
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF131 ZNF777 ZFAT ZBTB39 ZNF227 ZNF468 PRDM15 ZNF415 ZFX	9.75e-05	718	48	9	28
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	TRIO FARP1 PREX1	7.15e-04	66	48	3	722
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	HERC2 CREBBP	1.03e-03	18	48	2	91
GeneFamily	CD molecules\|Killer cell immunoglobulin like receptors	KIR2DL2 KIR2DL3	1.03e-03	18	48	2	620
GeneFamily	Basic leucine zipper proteins\|BTB domain containing	ZNF131 ZBTB39 BTBD9	5.40e-03	134	48	3	861
Coexpression	LAKE_ADULT_KIDNEY_C4_PROXIMAL_TUBULE_EPITHELIAL_CELLS_S2	TRIO FARP1 GLS SYNE2 PKHD1 PAM EPB41L4A	1.15e-06	176	80	7	M39223
Coexpression	GSE37301_HEMATOPOIETIC_STEM_CELL_VS_CD4_TCELL_UP	TGFBI FAM120A PIK3CG NEB TEP1 PREX1	1.68e-05	176	80	6	M8881
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK3 ABCC3 SEMA4D TRIO FARP1 SYNE2 PKHD1	5.44e-08	191	80	7	d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC3 SEMA4D TRIO FARP1 PKHD1 EPB41L4A	1.25e-06	191	80	6	1cb02007adb344f17ef73d58890f91298c7cf5a1
ToppCell	facs-Lung-nan-3m-Myeloid-Intermediate_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TGFBI SEMA4D PIK3CG FEM1C PREX1	9.16e-06	156	80	5	3f0b9e35d4da85c90759b930052e5b9c3cde9b15
ToppCell	facs-Lung-nan-3m-Myeloid-intermediate_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TGFBI SEMA4D PIK3CG FEM1C PREX1	9.16e-06	156	80	5	69e6e8810d1738a66c9821910f41498931cf30cc
ToppCell	Influenza_Severe-gd_T\|World / Disease group and Cell class	CNTNAP3B SYNE2 CNTNAP3 PRSS23 KIR2DL3	1.07e-05	161	80	5	b3cdaed4d58d57e3c5dbc904a09388f3bf949407
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c07-TYROBP\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	SEMA4D RAPGEF6 SYNE2 KIR2DL3 NEB	1.27e-05	167	80	5	ded4d6cccd3660662f12cf5a512de31d26325f1b
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_vein-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CNTNAP3B PTPRB CNTNAP3 PRSS23 EPB41L4A	1.27e-05	167	80	5	d7fe24cdc4b55a9555ce9e20699f5036b88148e9
ToppCell	Control-Endothelial_cells-Systemic_venous_endothelial_cells\|Control / group, cell type (main and fine annotations)	CNTNAP3B PTPRB STK32B PRSS23 EPB41L4A	1.47e-05	172	80	5	c55dce1ed3ed7312394b4e050e1de852a994e130
ToppCell	Adult-Endothelial-endothelial_cell_of_lymph_vessel-D122\|Adult / Lineage, Cell type, age group and donor	CNTNAP3B PTPRB STK32B CNTNAP3 PRSS23	1.51e-05	173	80	5	dba09ba9748871e38a16449d500ae4d7b405c42f
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC3 FARP1 SYNE2 PKHD1 CHRNA4	1.69e-05	177	80	5	2f81b26be89cc2fd8eafadaf7eae3c6ad6521462
ToppCell	COVID-19-kidney-Epi_(Mes)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ABCC3 DCHS2 FARP1 SYNE2 PKHD1	1.73e-05	178	80	5	544379f5a6145429762258d426b876bb36c112f5
ToppCell	PCW_13-14-Endothelial-Endothelial_mature-endo_arterial_(9)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	CNTNAP3B PTPRB PIK3CG CNTNAP3 PREX1	1.73e-05	178	80	5	c227da59dc7beb73f84405bf13356bdeb59d9338
ToppCell	COVID-19-kidney-PCT-S2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CNTNAP3B FARP1 STK32B SYNE2 PKHD1	1.83e-05	180	80	5	358923e4228035a3e90e2957392089219e90dcd7
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_vein-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CNTNAP3B PTPRB CNTNAP3 PRSS23 EPB41L4A	1.83e-05	180	80	5	27e8bbee388e64dd79d70b160b76d45b1f398006
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC3 DCHS2 AMACR FARP1 CHRNA4	1.98e-05	183	80	5	d73cac83cde82665f110baad7cf28db75f9ffe52
ToppCell	COVID-19-kidney-PCT-S1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ABCC3 FARP1 STK32B SYNE2 PKHD1	1.98e-05	183	80	5	6878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCell	COVID-19-kidney-PCT-S1\|kidney / Disease (COVID-19 only), tissue and cell type	ABCC3 FARP1 STK32B SYNE2 PKHD1	2.03e-05	184	80	5	51ed1ebfdef45149541917c66cbacad87072e51f
ToppCell	COVID-19-Endothelial_cells-Systemic_venous_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	CNTNAP3B PTPRB SYNE2 PRSS23 EPB41L4A	2.09e-05	185	80	5	f5e14181f45c37d13ee9e017a4c8bc248c353676
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CNTNAP3B ABCC3 FARP1 SYNE2 PKHD1	2.14e-05	186	80	5	b87acc80b7baa41681e4ed11d5537b9fbf5832f5
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_vein\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CNTNAP3B PTPRB CNTNAP3 PRSS23 EPB41L4A	2.20e-05	187	80	5	e35716f8b482be3bf5ab79f087a9caf67a9d197a
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CNTNAP3B PTPRB STK32B CNTNAP3 PRSS23	2.25e-05	188	80	5	c2805232618a7b6f844d34e37ad458a9923dbfe1
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SEMA4D TRIO FARP1 STK32B PKHD1	2.25e-05	188	80	5	63a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CNTNAP3B PTPRB STK32B CNTNAP3 PRSS23	2.25e-05	188	80	5	2db80767903703e7e0a1a37c598f7877a909ee94
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CNTNAP3B ABCC3 TRIO FARP1 PKHD1	2.31e-05	189	80	5	3b48b0d220cc24d5170713d61fa91f5bb6c21841
ToppCell	COVID-19-kidney-PCT-S2\|kidney / Disease (COVID-19 only), tissue and cell type	CNTNAP3B ABCC3 FARP1 SYNE2 PKHD1	2.31e-05	189	80	5	0be5c669b6b308bd98ddb70c84877c62a6244bbd
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK3 ABCC3 TRIO PKHD1 PRSS23	2.43e-05	191	80	5	9032aa974aa1b7b1095b8d1b58dcb087358a5001
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK3 ABCC3 TRIO PKHD1 PRSS23	2.43e-05	191	80	5	5717809a1476c20f65bce722c5a57cff92ee0d7a
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	TRIO FARP1 SYNE2 PKHD1 BTBD9	2.49e-05	192	80	5	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	nucseq-Endothelial-Endothelial_Lymphatic-LEC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CNTNAP3B PTPRB STK32B CNTNAP3 PRSS23	2.62e-05	194	80	5	f772a9f9ef8635aeaeb8b022dbb94e9672b36ead
ToppCell	nucseq-Endothelial-Endothelial_Lymphatic-LEC-LEC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CNTNAP3B PTPRB STK32B CNTNAP3 PRSS23	2.62e-05	194	80	5	3b73f2d305a7566f7ab567e5f18c82cd3d80e32c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC3 FARP1 SYNE2 PKHD1 EPB41L4A	2.62e-05	194	80	5	7002937e8903e037332a215d00fbc7c7843b33f2
ToppCell	nucseq-Endothelial-Endothelial_Lymphatic\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CNTNAP3B PTPRB STK32B CNTNAP3 PRSS23	2.62e-05	194	80	5	5d2b3ed5374e2ab10c1c7eb3a03139fc95036a48
ToppCell	background-Endothelial_cells\|background / Sample and Cell Type and Tumor Cluster (all cells)	PTPRB PAM PRSS23 BTBD9 EPB41L4A	2.75e-05	196	80	5	e6fb0bfab1779ec64a8c35d01519eaafbf62e977
ToppCell	10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	WSB1 ABCC3 TRIO CNTNAP3 PAM	2.75e-05	196	80	5	b8b9801181d7604871b48aebacb295d0a57a5eaf
ToppCell	Bronchial-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CNTNAP3B PTPRB STK32B CNTNAP3 PRSS23	2.89e-05	198	80	5	b3a020522e064bb61949d38e442f24026e339364
ToppCell	Bronchial-NucSeq-Endothelial-Endothelia_lymphatic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CNTNAP3B PTPRB STK32B CNTNAP3 PRSS23	2.89e-05	198	80	5	fc4b7c3ad52bc5c8b40fa04a156bfbb58afa2872
ToppCell	Bronchial-NucSeq-Endothelial-Endothelia_vascular-VE_pulmonary_venous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CNTNAP3B PTPRB CNTNAP3 PRSS23 EPB41L4A	2.96e-05	199	80	5	3a4deea6e11a0555d27497b7c9983350797aac69
ToppCell	COVID-19-lung-Capillary_2\|lung / Disease (COVID-19 only), tissue and cell type	CNTNAP3B PTPRB SYNE2 PRSS23 EPB41L4A	2.96e-05	199	80	5	793ce71b78a68033ef4419ed571e1dd86b40124f
ToppCell	368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	PAM ZNF227 KIR2DL3 FEM1C	5.33e-05	114	80	4	670c9802a59b39241abf6f2c12a3d1844c7db5e5
ToppCell	3'_v3-blood-Lymphocytic_T_CD4-T_CD4/CD8\|blood / Manually curated celltypes from each tissue	RAPGEF6 SYNE2 CNTNAP3 PKHD1	1.03e-04	135	80	4	ae2d3a42e567b5bade304c0caa497eb725be3565
ToppCell	PBMC-Control-Myeloid-Neutrophil-Neutrophil-Neu_1\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CNTNAP3B PTPRB AOC3 CNTNAP3	1.25e-04	142	80	4	191a13bba143ecdfc2bfd797c3ac191481388298
ToppCell	PBMC-Control-Myeloid-Neutrophil-Neutrophil-Neu_1\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CNTNAP3B PTPRB AOC3 CNTNAP3	1.28e-04	143	80	4	b405dba9a83a99cc7b53ce71772bc52a0bbb0d4e
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_vein-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CNTNAP3B PTPRB PRSS23 EPB41L4A	1.54e-04	150	80	4	4f31867cb85253ff6d22f3b02ef972a42cb41123
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ACSL6 ZBTB39 PTPRB MCM2	1.84e-04	157	80	4	2c946c6ab284fac3c25db688ed0aabe5a3f9ffa5
ToppCell	facs-Lung-3m-Hematologic-myeloid-intermediate_monocyte\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SEMA4D PIK3CG FEM1C PREX1	1.88e-04	158	80	4	b35bab2b93d0af821bfae18a358eb7dddaf3860f
ToppCell	facs-Lung-3m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l4\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SEMA4D PIK3CG FEM1C PREX1	1.88e-04	158	80	4	7bd4a64a610eb1cbcd3d07ea5258a55107cf6c00
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_B\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	TBCK PRSS23 KIR2DL3 SERPIND1	1.88e-04	158	80	4	1bf692f1e85f677cd62805437b7a59cfaf3b0449
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	DOCK3 SYNE2 HERC2 DYRK2	2.02e-04	161	80	4	5fba13f0aa5002f7eefe219e2c6a07e163f1a50d
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DOCK3 DPP10 PKHD1 NEB	2.07e-04	162	80	4	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HSD3B7 PTPRB AOC2 VPS29	2.12e-04	163	80	4	bb09e6ca3406eee0593d9a312db7e05934309dd2
ToppCell	390C-Fibroblasts-Fibroblast-F\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	HSD3B7 STK32B SERPIND1 CHRNA4	2.17e-04	164	80	4	2957065d7f1332c5280d47be7cc342286f84be3e
ToppCell	343B-Myeloid-Macrophage-SPP1+_Macrophage\|343B / Donor, Lineage, Cell class and subclass (all cells)	TGFBI ABCC3 AOC2 TEP1	2.17e-04	164	80	4	057ca87847373eff7fe97dd9f4358509e66ca4c3
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TGFBI HSPB6 AOC3 PRSS23	2.17e-04	164	80	4	01a7c335897128d3478b8b9b44fb461cab493084
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC3 FARP1 SYNE2 PKHD1	2.17e-04	164	80	4	1cb5fbd7050650047ad6f2ca792118e98d58d22b
ToppCell	Children_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DOCK3 CNTNAP3B DPP10 LRRTM3	2.17e-04	164	80	4	be49af6335f2505065cde2cb9800e4a5516811b1
ToppCell	367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	EIF5AL1 AOC3 PRDM15 ZNF415	2.17e-04	164	80	4	d2218d50e0e2d19f919dcb460b3840687c082810
ToppCell	390C-Fibroblasts-Fibroblast-F-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	HSD3B7 STK32B SERPIND1 CHRNA4	2.17e-04	164	80	4	82e57d618c6e59bca4a03d31caf35b6043dfcf52
ToppCell	356C-Myeloid-Macrophage-SPP1+_Macrophage_4\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	DOCK3 ZFAT AZIN2 ZNF468	2.27e-04	166	80	4	8d5d09f25e8903d481c2097fed435e69d42ccdb5
ToppCell	severe_influenza-gd_T\|World / disease group, cell group and cell class (v2)	SYNE2 CNTNAP3 PRSS23 KIR2DL3	2.43e-04	169	80	4	6d514dd2d1e5253bce49279f43aa2fa2b7c2653e
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	WSB1 CNTNAP3B GLS PKHD1	2.49e-04	170	80	4	928e42c51a7079c506f21c669c4e4c1a0df84d77
ToppCell	facs-Marrow-Granulocytes-24m-Hematologic-hematopoietic_stem_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCC3 AOC2 MERTK SERPIND1	2.49e-04	170	80	4	8d3c51364a332020810836e2055c60893c10d7f3
ToppCell	droplet-Liver-LIVER_NPC-30m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TGFBI DAB1 PRSS23 EPB41L4A	2.49e-04	170	80	4	a121e10099faaeb60251eec162f38caf7c4238c2
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	SEMA4D RAPGEF6 GLS SYNE2	2.54e-04	171	80	4	2e9a20f8980b78325c52065a9c14ab3656267c05
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC3 TRIO FARP1 PKHD1	2.60e-04	172	80	4	0c2d0bb767e5ce089b42ad49e8b303a103de2d5c
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC3 TRIO FARP1 PKHD1	2.60e-04	172	80	4	eeed177a03c116e9815a8e086d24efc9643b16a4
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B DCHS2 DPP10 CNTNAP3	2.66e-04	173	80	4	95c723b09254ae7131fe5ba0841472502e83269b
ToppCell	Adult-Endothelial-endothelial_cell_of_vein-D231\|Adult / Lineage, Cell type, age group and donor	CNTNAP3B PTPRB PRSS23 EPB41L4A	2.72e-04	174	80	4	2dd647c4fdf99fd1f7b838efef01baf2cbc3446d
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HSD3B7 PTPRB PAM PRSS23	2.78e-04	175	80	4	2e54961846c65b185d9bd6e305dd81205579d890
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HSD3B7 PTPRB PAM PRSS23	2.78e-04	175	80	4	efa6a05f7417d46141b6e635f258c126b7a03aa1
ToppCell	droplet-Liver-LIVER_NPC-30m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TGFBI DAB1 PRSS23 EPB41L4A	2.78e-04	175	80	4	f7cd2ef79d91d64976fcdb5f1e7343b24ba27456
ToppCell	3'-Child09-12-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DCHS2 HSPB6 AOC3 CNTNAP3	2.84e-04	176	80	4	a8875b4ba4abf6625cdeb67bf544ce1573c59060
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B DCHS2 DPP10 CNTNAP3	2.84e-04	176	80	4	72a2a01618ce836bc843395d5095e9090759b4a6
ToppCell	Fetal_29-31_weeks-Epithelial-club_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	WSB1 ABCC3 DPP10 BTBD9	2.84e-04	176	80	4	3bbac5c2397535631fce8fa98f6ddb4fe0260351
ToppCell	Adult-Endothelial-endothelial_cell_of_vein\|Adult / Lineage, Cell type, age group and donor	CNTNAP3B PTPRB PRSS23 EPB41L4A	2.84e-04	176	80	4	043683c61c5d1a7f8a4666a612310246bd3d83a2
ToppCell	facs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l39\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HSPB6 AOC3 HRC LRRTM3	2.90e-04	177	80	4	928118b0ed120ec01c7d753ce523ab609ac24e5f
ToppCell	COVID-19_Mild-Lymphoid_T/NK-NK_activated\|COVID-19_Mild / Disease group, lineage and cell class	SYNE2 MARF1 PRSS23 KIR2DL2	2.90e-04	177	80	4	6978a22fef40c8b455342373abe7593f5ede0fa4
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	EIF5AL1 HSD3B7 HSPB6 AOC3	2.90e-04	177	80	4	88403b055eb9fdf96e4695fb6e0d78179e30a1e3
ToppCell	facs-Marrow-Granulocytes-24m-Hematologic-MPP_Fraction_B\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCC3 AOC2 MERTK SERPIND1	2.90e-04	177	80	4	4a697866ed542d3201714234cee03451adf1dcc9
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	EIF5AL1 HSD3B7 HSPB6 AOC3	2.90e-04	177	80	4	8903aeaab61abd81a148ea623038c5114b8a183b
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B DCHS2 DPP10 CNTNAP3	2.96e-04	178	80	4	431e7557b8e8764e16e9e48368ce6bfa3c61561a
ToppCell	Adult-Endothelial-endothelial_cell_of_lymph_vessel-D231\|Adult / Lineage, Cell type, age group and donor	CNTNAP3B DCHS2 PTPRB STK32B	2.96e-04	178	80	4	c80ca7a2d3f976089a5e71d0cd9ba9a1c0bd2815
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_prolif-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TGFBI ZFAT ALDH18A1 BTBD9	2.96e-04	178	80	4	30d2b54462fd16222ad2e3806be6143e834b29e0
ToppCell	PCW_10-12-Endothelial-Endothelial_mature-lymphatic\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	CNTNAP3B PTPRB STK32B CNTNAP3	3.03e-04	179	80	4	ab3d08b51cd7a37582305615ee221c7a2af83b40
ToppCell	PCW_10-12-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	CNTNAP3B PTPRB STK32B CNTNAP3	3.03e-04	179	80	4	35fe9961e228ce255e3317fc244efa35b5adbf8b
ToppCell	10x5'-lymph-node_spleen-Myeloid_Mac-Intestinal_macrophages\|lymph-node_spleen / Manually curated celltypes from each tissue	TGFBI ABCC3 HSD3B7 MERTK	3.09e-04	180	80	4	7be7d7a6906fff6dbdecd9cb013d855aba4eda2a
ToppCell	10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8\|Liver / Manually curated celltypes from each tissue	RAPGEF6 GLS SYNE2 SLC39A10	3.16e-04	181	80	4	f2315414e714ac86211546a935660c4be6e85f1b
ToppCell	Epithelial-lung_neuroendocrine_cell_(PNEC)\|World / Lineage, Cell type, age group and donor	DOCK3 CNTNAP3B DPP10 LRRTM3	3.22e-04	182	80	4	57bf4ffb304324e2e392e196336a530d9f78fe0d
ToppCell	COVID-19-Heart-CM_3\|Heart / Disease (COVID-19 only), tissue and cell type	DOCK3 PAM LRRTM3 SLC39A10	3.22e-04	182	80	4	287fcc3897ae08841f6f85ae6c9cef16f75b1dd1
ToppCell	5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CNTNAP3B STK32B CNTNAP3 CHRNA4	3.29e-04	183	80	4	4d16bfbadf2cd13008c35e23dd2b5b4ecf92ee11
ToppCell	droplet-Limb_Muscle-nan-21m-Mesenchymal-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPB6 AOC3 HRC NEB	3.29e-04	183	80	4	6f5dbac2748f50105f0f548d189c42ef14287019
ToppCell	Control-Endothelial_cells-Pulmonary_venous_endothelial_cells\|Control / group, cell type (main and fine annotations)	CNTNAP3B PTPRB PRSS23 EPB41L4A	3.29e-04	183	80	4	46be9f96755c7b65aeac061d95d15abeb6466034
ToppCell	LPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FARP1 SYNE2 PKHD1 RIPK4	3.36e-04	184	80	4	42ce855b4f8475a8298192feec785bdc69bc5bb0
ToppCell	PCW_10-12-Endothelial-Endothelial_mature-endo_arterial_(9)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	CNTNAP3B PTPRB CNTNAP3 PREX1	3.36e-04	184	80	4	a809b0fa52df8a159f60f87eefcef61220af5e34
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive\|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK3 ABCC3 TRIO PAM	3.36e-04	184	80	4	d2bf0135eb56bb410997dccea39c5ede88a0617f
ToppCell	Endothelial-A-Donor_04\|World / lung cells shred on cell class, cell subclass, sample id	CNTNAP3B PTPRB CNTNAP3 PRSS23	3.43e-04	185	80	4	ae49c61f6ecf128fe2a958b8c75c83688da75f59
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_A_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPP10 GLS PAM LRRTM3	3.43e-04	185	80	4	4e40d3103ebf4a7066b7ce300b6ef700ba0e2863
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CNTNAP3B PTPRB STK32B CNTNAP3	3.43e-04	185	80	4	f9f48251bc33eb6bf2cff580d1a3207d21450aa0
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c3-EREG\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	TGFBI HSD3B7 STK32B MERTK	3.43e-04	185	80	4	7bff05d8d34616adbaa0ea0b69eb30aa906bb9f8
ToppCell	ILEUM-inflamed-(7)_Lymphatics\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	CNTNAP3B STK32B PRSS23 CHRNA4	3.43e-04	185	80	4	d711dd2e91cfee723dae1ccb2b910b8cf3becc3b
ToppCell	COVID-19-kidney-Mito-rich_PCT\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CNTNAP3B FARP1 SYNE2 PKHD1	3.43e-04	185	80	4	1bbc2ba8a20f72f61981b1301cdd6018cdd9150d
Drug	guazatine	AOC2 AOC3 EIF5A PLEKHM1	4.16e-07	18	80	4	CID000003526
Drug	o-phthalaldehyde	GLS AOC2 AOC3 PAM UROD	5.16e-07	45	80	5	CID000004807
Drug	isothiouronium	AOC2 AOC3 EIF5A	8.29e-07	6	80	3	CID000031429
Drug	o-dianisidine	DOCK3 DPP10 AOC2 AOC3 UROD	8.83e-07	50	80	5	CID000008411
Drug	dl-ornithine	AZIN2 GLS AOC2 AOC3 EIF5A ALDH18A1 UROD	4.47e-06	188	80	7	CID000000389
Drug	P-Nz	AOC2 AOC3 PAM	8.98e-06	12	80	3	CID000029146
Drug	DPGBG	AOC2 AOC3	1.22e-05	2	80	2	CID005356884
Drug	monopropionylcadaverine	AOC2 AOC3	1.22e-05	2	80	2	CID000194207
Drug	1-carboxymethylpyridinium	AOC2 AOC3	1.22e-05	2	80	2	CID000080439
Drug	supinidine	AOC2 AOC3	1.22e-05	2	80	2	CID000164663
Drug	diphenylglyoxal bis(guanylhydrazone	AOC2 AOC3	1.22e-05	2	80	2	CID000357080
Drug	AC1Q77R6	AOC2 AOC3	1.22e-05	2	80	2	CID000094259
Drug	p-dimethylaminomethylbenzaldehyde	AOC2 AOC3	1.22e-05	2	80	2	CID000193251
Drug	isoputreanine	AOC2 AOC3	1.22e-05	2	80	2	CID000171763
Drug	N-(3-aminopropyl)pyrrolidin-2-one	AOC2 AOC3	1.22e-05	2	80	2	CID000082111
Drug	benzylhydrazine	AOC2 AOC3 PAM	1.48e-05	14	80	3	CID000011157
Drug	citrullin	GLS EIF5A ALDH18A1 EIF5A2 UROD PADI1	1.66e-05	153	80	6	CID000000833
Drug	DFMO	ACTL7B AZIN2 AOC2 AOC3 EIF5A TOP3A	1.79e-05	155	80	6	CID000003009
Drug	procarbazine	AOC2 AOC3 ALDH18A1 MERTK TOP3A	1.93e-05	93	80	5	CID000004915
Drug	2,4,4'-trichlorobiphenyl	ACSL6 ZBTB39 DPP10 PIK3CG GLS SYNE2 TBCK DAB1 ALDH18A1 MCM2 CEP295 RIPK4 LRRTM3 PRSS23 SLC39A10 DYRK2	2.69e-05	1411	80	16	ctd:C081766
Drug	agmatine	AZIN2 AOC2 AOC3 EIF5A EIF5A2	3.01e-05	102	80	5	CID000000199
Drug	2,4,5,2',5'-pentachlorobiphenyl	ACSL6 ZBTB39 DPP10 PIK3CG GLS SYNE2 TBCK DAB1 ALDH18A1 MCM2 CEP295 RIPK4 LRRTM3 PRSS23 SLC39A10 DYRK2	3.47e-05	1441	80	16	ctd:C009828
Drug	AC1L1B7L	AOC2 AOC3	3.65e-05	3	80	2	CID000026477
Drug	(+)-Cyanustine	AOC2 AOC3	3.65e-05	3	80	2	CID000028846
Drug	propylglyoxal	AOC2 AOC3	3.65e-05	3	80	2	CID000123249
Drug	3-Hydroxycadaverine	AOC2 AOC3	3.65e-05	3	80	2	CID000435285
Drug	5-fluoropentane-1,4-diamine	AOC2 AOC3	3.65e-05	3	80	2	CID010011890
Drug	NSD-1531	AOC2 AOC3	3.65e-05	3	80	2	CID003014318
Drug	necic acid	AOC2 AOC3	3.65e-05	3	80	2	CID006440847
Drug	AC1L34PU	AOC2 AOC3	3.65e-05	3	80	2	CID000134498
Drug	N-(4-aminobutyl)aziridine	AOC2 AOC3	3.65e-05	3	80	2	CID000152643
Drug	alpha-difluoromethyl putrescine	AOC2 AOC3	3.65e-05	3	80	2	CID000135151
Drug	ketosuccinamate	AOC2 AOC3	3.65e-05	3	80	2	CID000439716
Drug	N-(3-aminopropyl)aziridine	AOC2 AOC3	3.65e-05	3	80	2	CID000014076
Drug	3-aminopropionamide	AOC2 AOC3	3.65e-05	3	80	2	CID000192802
Drug	pentafluorobenzamide	AOC2 AOC3	3.65e-05	3	80	2	CID000069547
Drug	acisoga	AOC2 AOC3	3.65e-05	3	80	2	CID000129397
Drug	Nazlinine	AOC2 AOC3	3.65e-05	3	80	2	CID000126237
Drug	5-aminopentanal	AOC2 AOC3	3.65e-05	3	80	2	CID000443849
Drug	h202	AOC2 AOC3	3.65e-05	3	80	2	CID000013826
Drug	amicarbalide	AOC2 AOC3	3.65e-05	3	80	2	CID000072074
Drug	C10974	AOC2 AOC3	3.65e-05	3	80	2	CID000443042
Drug	ethylmethylglyoxal bis(guanylhydrazone	AOC2 AOC3	3.65e-05	3	80	2	CID000129202
Drug	1-pyrroline	AOC2 AOC3 EIF5A	3.89e-05	19	80	3	CID000079803
Drug	N1-acetylspermidine	AOC2 AOC3 EIF5A	4.56e-05	20	80	3	CID000000496
Drug	Pridinol methanesulfonate salt [6856-31-1]; Down 200; 10.2uM; MCF7; HT_HG-U133A	SEMA4D FARP1 EIF5A2 ZFX FKBP14 DYRK2	6.31e-05	194	80	6	7214_DN
Drug	methylglyoxal bis(guanylhydrazone	AOC2 AOC3 EIF5A EIF5A2	6.33e-05	61	80	4	CID000009991
Drug	Aminopurine, 6-benzyl [1214-39-7]; Down 200; 17.8uM; MCF7; HT_HG-U133A	WSB1 SEMA4D FARP1 GLS TEP1 ZFX	6.49e-05	195	80	6	4748_DN
Drug	SC 19220; Down 200; 10uM; MCF7; HT_HG-U133A	WSB1 TRIO MERTK NEB TEP1 ZFX	6.86e-05	197	80	6	7060_DN
Drug	AC1L3XA1	AOC2 AOC3 EIF5A	7.03e-05	23	80	3	CID000123782
Drug	Bupropion hydrochloride [31677-93-7]; Up 200; 14.4uM; MCF7; HT_HG-U133A	ABCC3 TRIO PIK3CG GLS TEP1 SERPIND1	7.06e-05	198	80	6	3180_UP
Drug	Proguanil hydrochloride [637-32-1]; Up 200; 13.8uM; MCF7; HT_HG-U133A	WSB1 TRIO GLS NEB TEP1 ZFX	7.06e-05	198	80	6	3505_UP
Drug	Pirlindole mesylate [60762-57-4]; Up 200; 12.4uM; MCF7; HT_HG-U133A	ZBTB39 PTPRB AOC3 NEB CREBBP TOP3A	7.26e-05	199	80	6	6519_UP
Drug	malonamate	AOC2 AOC3	7.28e-05	4	80	2	CID000075367
Drug	Eovist (TN)	AOC2 AOC3	7.28e-05	4	80	2	CID009961939
Drug	N-acetyl-1,6-diaminohexane	AOC2 AOC3	7.28e-05	4	80	2	CID000162081
Drug	3-aminooxy-2-fluoro-1-propanamine	AOC2 AOC3	7.28e-05	4	80	2	CID000126496
Drug	2-Butene-1,4-diamine	AOC2 AOC3	7.28e-05	4	80	2	CID000148401
Drug	N-methylpyrrolinium	AOC2 AOC3	7.28e-05	4	80	2	CID000440932
Drug	1,4-diamino-2-butyne	AOC2 AOC3	7.28e-05	4	80	2	CID000124159
Drug	2-aminoresorcinol	AOC2 AOC3	7.28e-05	4	80	2	CID000069450
Drug	AC1Q3E6A	AOC2 AOC3	7.28e-05	4	80	2	CID000068318
Drug	spermic acid	AOC2 AOC3	7.28e-05	4	80	2	CID000167029
Drug	lanthionamine	AOC2 AOC3	7.28e-05	4	80	2	CID000070096
Drug	dimethylpyridine	AOC2 AOC3	7.28e-05	4	80	2	CID000011420
Drug	gamma-aminobutyraldehyde	AOC2 AOC3 UROD	9.09e-05	25	80	3	CID000000118
Drug	ifosfamide	SEMA4D ALDH18A1 PCYT2 PAM	9.15e-05	67	80	4	CID000003690
Drug	piperonyl butoxide	DOCK3 ABCC3 UROD AP3D1	9.15e-05	67	80	4	CID000005794
Drug	phenamil	AOC2 AOC3 PKHD1	1.02e-04	26	80	3	CID000004755
Drug	geranylamine	AOC2 AOC3	1.21e-04	5	80	2	CID000160248
Drug	phenamidine	AOC2 AOC3	1.21e-04	5	80	2	CID000064948
Drug	NSD 1024	AOC2 AOC3	1.21e-04	5	80	2	CID000188951
Drug	N(8)-(2-carboxyethyl)spermidine	AOC2 AOC3	1.21e-04	5	80	2	CID000125245
Drug	Nsc82118	AOC2 AOC3	1.21e-04	5	80	2	CID000164749
Drug	perhydroazepinyl	AOC2 AOC3	1.21e-04	5	80	2	CID000123152
Drug	2-fluoroputrescine	AOC2 AOC3	1.21e-04	5	80	2	CID000147066
Drug	pelletierine	AOC2 AOC3	1.21e-04	5	80	2	CID000092987
Drug	1,4-diamino-2-butanone	AOC2 AOC3	1.21e-04	5	80	2	CID000151733
Drug	piperideine	AOC2 AOC3	1.21e-04	5	80	2	CID000068161
Drug	NSD 1039	AOC2 AOC3	1.21e-04	5	80	2	CID000193408
Drug	oxosparteine	AOC2 AOC3	1.21e-04	5	80	2	CID000097492
Drug	alpha-hydrazinohistidine	AOC2 AOC3	1.21e-04	5	80	2	CID000169499
Drug	tyrosine	AOC2 AOC3 UROD	1.43e-04	29	80	3	CID005460802
Drug	AC1ODVCS	KIR2DL2 KIR2DL3 UROD	1.58e-04	30	80	3	CID000111104
Drug	16 d	AOC2 AOC3 EIF5A	1.58e-04	30	80	3	CID000016401
Drug	dicyclohexyl phthalate	TGFBI ABCC3 PTPRB AOC3 PCYT2 RIPK4 REST CREBBP AP3D1 VPS29 TOP3A	1.59e-04	836	80	11	ctd:C036042
Drug	NSC614854	AOC2 AOC3	1.81e-04	6	80	2	CID000122633
Drug	trihydroxyphenylalanine	AOC2 AOC3	1.81e-04	6	80	2	CID000591034
Drug	FF-705	AOC2 AOC3	1.81e-04	6	80	2	CID000126643
Drug	1,4-dimethylputrescine	AOC2 AOC3	1.81e-04	6	80	2	CID000162247
Drug	cyclohexanone oxime	AOC2 AOC3	1.81e-04	6	80	2	CID000007517
Drug	ethylglyoxal	AOC2 AOC3	1.81e-04	6	80	2	CID000145744
Drug	AC1L1AOE	AOC2 AOC3 EIF5A	1.93e-04	32	80	3	CID000001078
Drug	MW 1	TGFBI SEMA4D DAB1 UROD CREBBP	1.93e-04	151	80	5	CID000073965
Drug	methylglyoxal	HSD3B7 PTPRB AOC2 AOC3 PGM3	2.32e-04	157	80	5	CID000000880
Drug	putreanine	AOC2 AOC3	2.53e-04	7	80	2	CID000161506
Drug	AC1L3Y6U	AOC2 AOC3	2.53e-04	7	80	2	CID000097282
Drug	2-hydrazinopyridine	AOC2 AOC3	2.53e-04	7	80	2	CID000078645
Drug	AC1L28PE	AOC2 AOC3	2.53e-04	7	80	2	CID000067954
Drug	ISMP	HRC MERTK	2.53e-04	7	80	2	CID003082200
Disease	Seizures	TBCK PCYT2 PAM REST TRRAP AP3D1 CHRNA4	1.85e-06	218	78	7	C0036572
Disease	autism spectrum disorder (implicated_via_orthology)	CSDE1 CNTNAP3B CNTNAP3 CREBBP PREX1	5.30e-05	152	78	5	DOID:0060041 (implicated_via_orthology)
Disease	autosomal recessive intellectual developmental disorder (implicated_via_orthology)	CNTNAP3B CNTNAP3	1.91e-04	8	78	2	DOID:0060308 (implicated_via_orthology)
Disease	Autistic Disorder	CSDE1 PIK3CG DAB1 TRRAP CHRNA4	6.50e-04	261	78	5	C0004352
Disease	serum alanine aminotransferase measurement, response to combination chemotherapy	SEMA4D MCM2 CEP295	8.92e-04	71	78	3	EFO_0004735, EFO_0007965
Disease	coronary artery disease	DPP10 FARP1 STK32B GLS DAB1 PKHD1 REST MERTK EPB41L4A PREX1	1.17e-03	1194	78	10	EFO_0001645
Disease	cognitive function measurement	DOCK3 TGFBI PMS2P3 SEMA4D FAM120A FARP1 STK32B PKHD1 PRSS23 PREX1 PLEKHM1	1.34e-03	1434	78	11	EFO_0008354
Disease	kidney disease (biomarker_via_orthology)	TGFBI ABCC3	1.40e-03	21	78	2	DOID:557 (biomarker_via_orthology)
Disease	DNA methylation	DCHS2 ZFAT DPP10 TRIO PIK3CG STK32B PKHD1	1.76e-03	656	78	7	GO_0006306
Disease	TEMPS-A questionnaire	ZFAT CEP295	1.99e-03	25	78	2	EFO_0004783
Disease	pancreatic ductal adenocarcinoma (is_marker_for)	PTPRB PIK3CG	2.32e-03	27	78	2	DOID:3498 (is_marker_for)
Disease	Visual seizure	PAM REST CHRNA4	2.46e-03	101	78	3	C0270824
Disease	Epileptic drop attack	PAM REST CHRNA4	2.46e-03	101	78	3	C0270846
Disease	Generalized seizures	PAM REST CHRNA4	2.46e-03	101	78	3	C0234533
Disease	Clonic Seizures	PAM REST CHRNA4	2.46e-03	101	78	3	C0234535
Disease	Vertiginous seizure	PAM REST CHRNA4	2.46e-03	101	78	3	C0422855
Disease	Gustatory seizure	PAM REST CHRNA4	2.46e-03	101	78	3	C0422854
Disease	Seizures, Somatosensory	PAM REST CHRNA4	2.46e-03	101	78	3	C0422850
Disease	Olfactory seizure	PAM REST CHRNA4	2.46e-03	101	78	3	C0422853
Disease	Seizures, Auditory	PAM REST CHRNA4	2.46e-03	101	78	3	C0422852
Disease	Generalized Absence Seizures	PAM REST CHRNA4	2.46e-03	101	78	3	C4505436
Disease	Convulsive Seizures	PAM REST CHRNA4	2.46e-03	101	78	3	C0751494
Disease	Seizures, Sensory	PAM REST CHRNA4	2.46e-03	101	78	3	C0751496
Disease	Jacksonian Seizure	PAM REST CHRNA4	2.46e-03	101	78	3	C0022333
Disease	Non-epileptic convulsion	PAM REST CHRNA4	2.46e-03	101	78	3	C0751056
Disease	Atonic Absence Seizures	PAM REST CHRNA4	2.46e-03	101	78	3	C0751123
Disease	Complex partial seizures	PAM REST CHRNA4	2.46e-03	101	78	3	C0149958
Disease	Single Seizure	PAM REST CHRNA4	2.46e-03	101	78	3	C0751110
Disease	Epileptic Seizures	PAM REST CHRNA4	2.46e-03	101	78	3	C4317109
Disease	Nonepileptic Seizures	PAM REST CHRNA4	2.46e-03	101	78	3	C3495874
Disease	cognitive function measurement, self reported educational attainment	FAM120A PKHD1 PAM PREX1 PLEKHM1	2.52e-03	355	78	5	EFO_0004784, EFO_0008354
Disease	Tonic Seizures	PAM REST CHRNA4	2.53e-03	102	78	3	C0270844
Disease	Absence Seizures	PAM REST CHRNA4	2.53e-03	102	78	3	C4316903
Disease	Convulsions	PAM REST CHRNA4	2.53e-03	102	78	3	C4048158

Protein segments in the cluster

Peptide	Gene	Start	Entry
DHHATNGVVHLIDKV	TGFBI	221	Q15582
GDFAVTHLTKAHLFH	CHRNA4	131	P43681
TGVKHLHHKAQEFDI	PGM3	351	O95394
FTVDKHTHHFQAKGD	CNTNAP3	286	Q9BZ76
GHAFTDDHLHIIEHI	ACTL7B	241	Q9Y614
HEVAAAVAGAHVVIH	HSD3B7	71	Q9H2F3
EEVVHHDHNKERGSF	AMACR	301	Q9UHK6
KKHHVEVVGVSFHIG	AZIN2	186	Q96A70
EKHKEVFFVIHLHAG	CREBBP	1626	Q92793
VFAYRVHTHHLGKVV	PAM	231	P19021
HSHSDHRFLGTVEKE	CSDE1	421	O75534
IIHGTADTKVHFQHS	DPP10	721	Q8N608
LGTVHTHSAHFKVDL	AOC3	516	Q16853
AKICFHHHFSVVERV	AP3D1	1086	O14617
HAVCVVGVEAHVDIH	PADI1	16	Q9ULC6
HVAAAEGHVEVVKFL	GLS	591	O94925
EALHFGHHDVFKILQ	GLS	626	O94925
VDSHVAKHIFDHVIG	ABCC3	781	O15438
GETHEQVHSILHFKD	SERPIND1	171	P05546
HVDSHGHNVFKERIS	MCM2	206	P49736
VLGTVHTHAFHFKLD	AOC2	511	O75106
HTHAFHFKLDLDVAG	AOC2	516	O75106
DPEHVGAFVDAVHKH	UROD	346	P06132
VEHKADLEVSNRHGH	FEM1C	136	Q96JP0
KEFEKHGAVVNESHH	FKBP14	166	Q9NWM8
HHIRVHSAKKFFVEE	REST	176	Q13127
KHVFEHTFHRLEAGE	PTPRB	956	P23467
FKDTLHLIGEHHDGV	KIR2DL2	66	P43627
KVVGEHVEVHARHEE	HSPB6	91	O14558
FKHTVGHIILSEHKG	MERTK	96	Q12866
FKDTLHLIGEHHDGV	KIR2DL3	66	P43628
KHEDLGHVALSLVHA	HERC2	1446	O95714
HGHAKVHLVGIDIFT	EIF5A2	51	Q9GZV4
HIGHVDFLEKVHRLA	PCYT2	226	Q99447
YHQAKHHHGVEVKEV	PMS2P3	51	Q13401
HGHAKVHLVGIDIFT	EIF5A	51	P63241
HVKVAQSIEDHHQEV	FAM120A	156	Q9NZB2
DHIHKYGSSHTDVIV	ALDH18A1	686	P54886
AHVKEDVTVGSLVHH	DCHS2	1626	Q6V1P9
HGHAKVHLVGIDIFT	EIF5AL1	51	Q6IS14
HVLGVGLAVHEKFVH	DOCK3	1591	Q8IZD9
IFDEKTGALQHHHAV	DAB1	96	O75553
ALEDKIVEFHHNHIG	FARP1	191	Q9Y4F1
HGFHIILVHKNQASE	MARF1	466	Q9Y4F3
TAVGEIDHVHILSEH	BTBD9	11	Q96Q07
KVSSEHFIQSHHGDL	CEP295	1491	Q9C0D2
TKGSVVLDHVFHHVN	EPB41L4A	36	Q9HCS5
LLTANGSEIHKHVHF	SLC22A15	76	Q8IZD6
HLDILAVQEGKHFHS	SLC39A10	111	Q9ULF5
VVKAYDHKVHQHVAL	DYRK2	236	Q92630
FTVDKHTHHFQAKGD	CNTNAP3B	286	Q96NU0
AVFIHGLHAKHIRAE	PLEKHM1	56	Q9Y4G2
TTAKEVVFHAVHEFG	RAPGEF6	771	Q8TEU7
VETAATEAELKHHHV	SYNE2	2861	Q8WXH0
TEAELKHHHVTLEAS	SYNE2	2866	Q8WXH0
DAEHISFHKIIAGSV	LRRTM3	411	Q86VH5
VDVLRDHIHVHFKDI	PRDM15	941	P57071
AEKHVLTAAHCIHDG	PRSS23	166	O95084
LENGIIHHVSDKHQF	PREX1	471	Q8TCU6
HEAEVLTVKEVKGHH	PKHD1	2906	P08F94
GALHKAISLEHAVHI	SEMA4D	446	Q92854
KEEVEAVSGEHHHHV	HRC	326	P23327
HLAAAHGHSEVVEEL	RIPK4	756	P57078
GLHSFEQVKAIHIHS	ACSL6	646	Q9UKU0
IHVAFHLCVDDHVKS	C12orf4	426	Q9NQ89
HEQLTIHGKDHESVF	PIK3CG	336	P48736
SEADIHLLVHVHKHV	UHRF1BP1L	801	A0JNW5
HIKEVHGAAQEALVF	ZFAT	476	Q9P243
LFAQHIVTIVHHVKE	THRAP3	626	Q9Y2W1
IVTIVHHVKEHHFGS	THRAP3	631	Q9Y2W1
LKFIAEHGASHLLEH	TEP1	841	Q99973
VIVGHVAKHTAEFAA	TBCK	846	Q8TEA7
IFHRIKVTHDHKDGI	TOP3A	266	Q13472
AKDFHVVRGHILDHL	ZBTB39	461	O15060
FHTVTLEQHEKHDIE	ZNF415	116	Q09FC8
LISGHTHKFEAFEHE	VPS29	111	Q9UBQ0
GHVEHVVHDSVVEAE	ZFX	151	P17010
NTDLHIHFRVHTGEK	ZNF227	476	Q86WZ6
EHGHVHITDFNIATV	STK32B	156	Q9NY57
ITLIVDGHHFKAHKA	ZNF131	36	P52739
KLEGHHHDVVACDFS	WSB1	251	Q9Y6I7
IHQRVHAGKHEVSFI	ZNF777	681	Q9ULD5
HIGEFCFHEIEKDIH	ZNF468	81	Q5VIY5
VAAQEKSFHHVTHDL	TRRAP	1231	Q9Y4A5
SKAVHHVLDVIHEVL	TRIO	531	O75962
HFHHRAVTDTVSDVK	NEB	5321	P20929