Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	organelle assembly	CNOT6 DNHD1 ODF2L CNOT6L CCDC28B SDCCAG8 KIAA0586 EIF5B RNF213 CFAP74 RB1CC1 ODF2 VPS13B PCM1 KIF3A KPNB1	1.66e-05	1138	86	16	GO:0070925
GeneOntologyCellularComponent	cilium	GSTM3 CUL3 DNHD1 ODF2L PDE6A BSG SDCCAG8 KIAA0586 CFAP74 ODF2 PCM1 KIF3A DNAH11	7.41e-05	898	86	13	GO:0005929
GeneOntologyCellularComponent	centriole	ODF2L SDCCAG8 KIAA0586 ODF2 PCM1 KIF3A	7.76e-05	172	86	6	GO:0005814
GeneOntologyCellularComponent	centrosome	CUL3 ODF2L CCDC28B PPP1R12A SDCCAG8 MID1 KIAA0586 SLMAP ODF2 PCM1 KIF3A	3.12e-04	770	86	11	GO:0005813
GeneOntologyCellularComponent	9+2 motile cilium	GSTM3 CUL3 DNHD1 CFAP74 ODF2 DNAH11	4.50e-04	238	86	6	GO:0097729
GeneOntologyCellularComponent	motile cilium	GSTM3 CUL3 DNHD1 CFAP74 ODF2 KIF3A DNAH11	6.54e-04	355	86	7	GO:0031514
GeneOntologyCellularComponent	cytoplasmic region	DNHD1 CFAP74 TRAK2 UNC13A KIF3A DNAH11 NLRP5	7.10e-04	360	86	7	GO:0099568
GeneOntologyCellularComponent	ciliary basal body	ODF2L SDCCAG8 KIAA0586 ODF2 PCM1	1.27e-03	195	86	5	GO:0036064
GeneOntologyCellularComponent	non-motile cilium	PDE6A BSG SDCCAG8 PCM1 KIF3A	1.30e-03	196	86	5	GO:0097730
GeneOntologyCellularComponent	microtubule organizing center	CUL3 ODF2L CCDC28B PPP1R12A SDCCAG8 MID1 KIAA0586 SLMAP ODF2 PCM1 KIF3A	1.34e-03	919	86	11	GO:0005815
GeneOntologyCellularComponent	sperm flagellum	GSTM3 CUL3 DNHD1 CFAP74 ODF2	1.91e-03	214	86	5	GO:0036126
GeneOntologyCellularComponent	centriolar satellite	ODF2L SDCCAG8 MID1 PCM1	1.93e-03	128	86	4	GO:0034451
GeneOntologyCellularComponent	CCR4-NOT complex	CNOT6 CNOT6L	1.93e-03	16	86	2	GO:0030014
HumanPheno	Perifollicular hyperkeratosis	KRT81 KRT83 KRT86	9.87e-07	4	33	3	HP:0007468
HumanPheno	Abnormal perifollicular morphology	KRT81 KRT83 KRT86	4.89e-06	6	33	3	HP:0031285
Domain	Odf2-rel	ODF2L ODF2	2.05e-05	2	85	2	IPR026099
Domain	P-loop_NTPase	DHX15 DNHD1 LRRIQ1 EIF5B RNF213 ABCC12 ZNFX1 POLQ ATAD2 MYO16 KIF3A DNAH11 NLRP5	1.14e-04	848	85	13	IPR027417
Domain	Keratin_2_head	KRT81 KRT83 KRT86	1.72e-04	24	85	3	IPR032444
Domain	Keratin_2_head	KRT81 KRT83 KRT86	1.72e-04	24	85	3	PF16208
Domain	Keratin_II	KRT81 KRT83 KRT86	2.19e-04	26	85	3	IPR003054
Domain	AlbA_2	SLFN12L SLFN12	4.24e-04	7	85	2	PF04326
Domain	Schlafen	SLFN12L SLFN12	4.24e-04	7	85	2	IPR029684
Domain	Schlafen_AAA_dom	SLFN12L SLFN12	4.24e-04	7	85	2	IPR007421
Domain	ZF_BBOX	TRIM51 MID2 MYCBP2 MID1	4.86e-04	80	85	4	PS50119
Domain	AAA+_ATPase	DHX15 RNF213 ABCC12 ATAD2 DNAH11	5.08e-04	144	85	5	IPR003593
Domain	AAA	DHX15 RNF213 ABCC12 ATAD2 DNAH11	5.08e-04	144	85	5	SM00382
Domain	Znf_B-box	TRIM51 MID2 MYCBP2 MID1	5.09e-04	81	85	4	IPR000315
Domain	COS_domain	MID2 MID1	1.31e-03	12	85	2	IPR017903
Domain	COS	MID2 MID1	1.31e-03	12	85	2	PS51262
Domain	Pept_C14_p20	MALT1 CASP7	1.80e-03	14	85	2	IPR001309
Domain	Dynein_HC_stalk	DNHD1 DNAH11	1.80e-03	14	85	2	IPR024743
Domain	Dynein_heavy_dom-2	DNHD1 DNAH11	1.80e-03	14	85	2	IPR013602
Domain	Caspase-like_dom	MALT1 CASP7	1.80e-03	14	85	2	IPR029030
Domain	DHC_N2	DNHD1 DNAH11	1.80e-03	14	85	2	PF08393
Domain	MT	DNHD1 DNAH11	1.80e-03	14	85	2	PF12777
Domain	CASPASE_P20	MALT1 CASP7	1.80e-03	14	85	2	PS50208
Domain	-	MALT1 CASP7	1.80e-03	14	85	2	3.40.50.1460
Domain	DHC_fam	DNHD1 DNAH11	2.07e-03	15	85	2	IPR026983
Domain	Bbox_C	MID2 MID1	2.07e-03	15	85	2	IPR003649
Domain	BBC	MID2 MID1	2.07e-03	15	85	2	SM00502
Domain	Dynein_heavy_dom	DNHD1 DNAH11	2.07e-03	15	85	2	IPR004273
Domain	Dynein_heavy	DNHD1 DNAH11	2.07e-03	15	85	2	PF03028
Domain	Intermediate_filament_CS	KRT81 KRT83 KRT86	2.97e-03	63	85	3	IPR018039
Domain	BBOX	TRIM51 MID2 MID1	3.84e-03	69	85	3	SM00336
Domain	Butyrophylin	TRIM51 MID2 MID1	4.00e-03	70	85	3	IPR003879
Domain	Filament	KRT81 KRT83 KRT86	4.16e-03	71	85	3	SM01391
Domain	-	TRIM51 MID2 MID1	4.16e-03	71	85	3	4.10.45.10
Domain	Prefoldin	SLMAP TRAK2 RB1CC1	4.33e-03	72	85	3	IPR009053
Domain	zf-B_box	TRIM51 MID2 MID1	4.33e-03	72	85	3	PF00643
Domain	IF	KRT81 KRT83 KRT86	4.33e-03	72	85	3	PS00226
Domain	Filament	KRT81 KRT83 KRT86	4.50e-03	73	85	3	PF00038
Domain	IF	KRT81 KRT83 KRT86	5.03e-03	76	85	3	IPR001664
Domain	IQ	LRRIQ1 SCN3A MYO16	6.01e-03	81	85	3	SM00015
Domain	-	CNOT6 CNOT6L	6.20e-03	26	85	2	3.60.10.10
Domain	Exo_endo_phos	CNOT6 CNOT6L	6.20e-03	26	85	2	PF03372
Domain	Endo/exonuclease/phosphatase	CNOT6 CNOT6L	6.67e-03	27	85	2	IPR005135
Domain	-	DHX15 DNHD1 EIF5B RNF213 ABCC12 ZNFX1 POLQ ATAD2 DNAH11	6.77e-03	746	85	9	3.40.50.300
Domain	Leu-rich_rpt	CNOT6 OPTC LRRIQ1 CNOT6L NLRP5	7.92e-03	271	85	5	IPR001611
Domain	IQ_motif_EF-hand-BS	LRRIQ1 SCN3A MYO16	8.04e-03	90	85	3	IPR000048
Domain	Leu-rich_rpt_typical-subtyp	CNOT6 OPTC LRRIQ1 CNOT6L	8.70e-03	177	85	4	IPR003591
Domain	LRR_TYP	CNOT6 OPTC LRRIQ1 CNOT6L	8.70e-03	177	85	4	SM00369
Domain	IQ	LRRIQ1 SCN3A MYO16	8.79e-03	93	85	3	PS50096
Domain	SPRY	TRIM51 MID2 MID1	9.05e-03	94	85	3	PF00622
Domain	SPRY_dom	TRIM51 MID2 MID1	9.05e-03	94	85	3	IPR003877
Pubmed	Structure and site of expression of a murine type II hair keratin.	KRT81 KRT83 KRT86	1.73e-08	3	91	3	1372089
Pubmed	Transient expression of mouse hair keratins in transfected HeLa cells: interactions between "hard" and "soft" keratins.	KRT81 KRT83 KRT86	1.73e-08	3	91	3	1712823
Pubmed	Novel KRT83 and KRT86 mutations associated with monilethrix.	KRT81 KRT83 KRT86	1.73e-08	3	91	3	25557232
Pubmed	Keratins of the human hair follicle.	KRT81 KRT83 KRT86	6.92e-08	4	91	3	15797458
Pubmed	Role of Ca2+ transients at the node of the mouse embryo in breaking of left-right symmetry.	NODAL KIF3A DNAH11	6.92e-08	4	91	3	32743070
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	DHX15 CUL3 LIMA1 CAD NUMBL PPP1R12A IGHM PYGB TLN2 ZNFX1 LANCL2 UNC13A PCM1 WNK2 KIF3A KPNB1 DNAH11	1.62e-07	1431	91	17	37142655
Pubmed	Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.	DHX15 GSTM3 CUL3 CAD MYCBP2 POLR1E PPP1R12A GOLIM4 EIF5B PSMD1 RBFA KIF3A KPNB1	1.92e-07	809	91	13	32129710
Pubmed	ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold.	DHX15 CUL3 LIMA1 CAD P3H1 PPP1R12A PYGB PSMD1 WNK2 KPNB1	3.07e-07	451	91	10	36168627
Pubmed	Defining the membrane proteome of NK cells.	CNOT6 CUL3 GDPD1 CAD MYCBP2 BSG P3H1 GCC2 GOLIM4 RNF213 PYGB PSMD1 PCM1 ITPR1 KPNB1	3.59e-07	1168	91	15	19946888
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	GSTM3 NRBP1 MALT1 CNOT6L MYCBP2 POLR1E BSG PPP1R12A AHCY SLMAP PSMD1 RIOK3 SH3BP5L RB1CC1 POLQ	1.17e-06	1284	91	15	17353931
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	NRBP1 SETDB1 ODF2L MYCBP2 KRT83 AHCY PSMD1 TLN2 ZNFX1 ANKRD36 VPS26A ODF2 PCM1 KIF3A KPNB1	1.19e-06	1285	91	15	35914814
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	CNOT6 DHX15 GSTM3 LIMA1 CAD MYCBP2 P3H1 PPP1R12A AHCY GOLIM4 EIF5B RB1CC1 LANCL2 PCM1 KPNB1	1.33e-06	1297	91	15	33545068
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	CUL3 LIMA1 CAD NUMBL MYCBP2 PPP1R12A TLN2 ZNFX1 UNC13A PCM1 WNK2 KIF3A KPNB1	1.35e-06	963	91	13	28671696
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	MALT1 ODF2L TUT4 MID2 NUMBL MYCBP2 GCC2 PPP1R12A WNT7B SDCCAG8 GAS6 RNF213 PSMD1 VPS13B PCM1 WNK2	1.47e-06	1489	91	16	28611215
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	CNOT6 DHX15 CUL3 ODF2L CNOT6L BSG P3H1 PPP1R12A AHCY TLN2 VPS13B PCM1 ITPR1 KPNB1	1.81e-06	1155	91	14	20360068
Pubmed	Proteomic analysis reveals novel ligands and substrates for LNX1 E3 ubiquitin ligase.	MID2 NUMBL MYCBP2 MID1 PCM1	2.12e-06	79	91	5	29121065
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	CUL3 MYCBP2 POLR1E BSG KRT81 P3H1 GCC2 IGHM SLMAP PSMD1 ABCC12 LANCL2 KIF3A	2.17e-06	1005	91	13	19615732
Pubmed	Genetic Analysis Reveals a Hierarchy of Interactions between Polycystin-Encoding Genes and Genes Controlling Cilia Function during Left-Right Determination.	NODAL KIF3A DNAH11	2.82e-06	11	91	3	27272319
Pubmed	Cluap1 localizes preferentially to the base and tip of cilia and is required for ciliogenesis in the mouse embryo.	ODF2 NODAL KIF3A	2.82e-06	11	91	3	23742838
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	CAD NUMBL MYCBP2 BSG P3H1 GOLIM4 RNF213 PSMD1 RB1CC1 ODF2 PUM1 ITPR1 KPNB1	3.46e-06	1049	91	13	27880917
Pubmed	Characterization of a 300 kbp region of human DNA containing the type II hair keratin gene domain.	KRT81 KRT83 KRT86	3.75e-06	12	91	3	10692104
Pubmed	Discovery of a Human Testis-specific Protein Complex TEX101-DPEP3 and Selection of Its Disrupting Antibodies.	GSTM3 CUL3 PDE6A BSG PYGB PSMD1 KPNB1	4.30e-06	249	91	7	30097533
Pubmed	Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.	DHX15 LIMA1 CAD NUMBL MYCBP2 PPP1R12A SH3BP5L	5.03e-06	255	91	7	15324660
Pubmed	Left-right symmetry breaking in mice by left-right dynein may occur via a biased chromatid segregation mechanism, without directly involving the Nodal gene.	NODAL DNAH11	6.77e-06	2	91	2	23316472
Pubmed	Mid1/Mid2 expression in craniofacial development and a literature review of X-linked opitz syndrome.	MID2 MID1	6.77e-06	2	91	2	26788540
Pubmed	A missense mutation in the type II hair keratin hHb3 is associated with monilethrix.	KRT83 KRT86	6.77e-06	2	91	2	15744029
Pubmed	CNOT6/6L-mediated mRNA degradation in ovarian granulosa cells is a key mechanism of gonadotropin-triggered follicle development.	CNOT6 CNOT6L	6.77e-06	2	91	2	34788619
Pubmed	Schlafen 12 mediates the effects of butyrate and repetitive mechanical deformation on intestinal epithelial differentiation in human Caco-2 intestinal epithelial cells.	SLFN12L SLFN12	6.77e-06	2	91	2	30875077
Pubmed	Lack of reproducible growth inhibition by Schlafen1 and Schlafen2 in vitro.	SLFN12L SLFN12	6.77e-06	2	91	2	18479948
Pubmed	The Ccr4a (CNOT6) and Ccr4b (CNOT6L) deadenylase subunits of the human Ccr4-Not complex contribute to the prevention of cell death and senescence.	CNOT6 CNOT6L	6.77e-06	2	91	2	21233283
Pubmed	A variable monilethrix phenotype associated with a novel mutation, Glu402Lys, in the helix termination motif of the type II hair keratin hHb1.	KRT81 KRT86	6.77e-06	2	91	2	9665406
Pubmed	Macrophage activation and differentiation signals regulate schlafen-4 gene expression: evidence for Schlafen-4 as a modulator of myelopoiesis.	SLFN12L SLFN12	6.77e-06	2	91	2	21249125
Pubmed	A new mutation in the type II hair cortex keratin hHb1 involved in the inherited hair disorder monilethrix.	KRT81 KRT86	6.77e-06	2	91	2	9402962
Pubmed	UM171 Preserves Epigenetic Marks that Are Reduced in Ex Vivo Culture of Human HSCs via Potentiation of the CLR3-KBTBD4 Complex.	DHX15 CUL3 LIMA1 NUMBL AHCY SLMAP TLN2	6.79e-06	267	91	7	33417871
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	DHX15 CAD MYCBP2 EIF5B PYGB PSMD1 PUM1 ATAD2 PCM1 KPNB1	8.34e-06	653	91	10	22586326
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	CNOT6 CUL3 SETDB1 LIMA1 CNOT6L CCDC28B NUMBL MYCBP2 GCC2 PPP1R12A SDCCAG8 EIF5B KIF3A KPNB1	8.45e-06	1321	91	14	27173435
Pubmed	Essential requirement of mammalian Pumilio family in embryonic development.	PUM1 NODAL NLRP5	9.47e-06	16	91	3	30256721
Pubmed	Comprehensive analysis of keratin gene clusters in humans and rodents.	KRT81 KRT83 KRT86	9.47e-06	16	91	3	15085952
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	DHX15 ZC3H7A CAD MYCBP2 POLR1E AHCY EIF5B PYGB PSMD1 RIOK3 VPS26A PUM1 ATAD2 KPNB1	1.11e-05	1353	91	14	29467282
Pubmed	Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins.	LIMA1 CAD MYCBP2 AHCY SH3BP5L PCM1	1.11e-05	190	91	6	15161933
Pubmed	RNF168 and USP10 regulate topoisomerase IIα function via opposing effects on its ubiquitylation.	DHX15 LIMA1 PCM1	1.37e-05	18	91	3	27558965
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	DHX15 LIMA1 CAD MYCBP2 KRT86 AHCY EIF5B PSMD1 RB1CC1 PUM1 PCM1 KPNB1	1.48e-05	1024	91	12	24711643
Pubmed	PERP regulates enamel formation via effects on cell-cell adhesion and gene expression.	KRT81 KRT83 KRT86	1.63e-05	19	91	3	21285247
Pubmed	The CP110-interacting proteins Talpid3 and Cep290 play overlapping and distinct roles in cilia assembly.	KIAA0586 ODF2 PCM1	1.63e-05	19	91	3	24421332
Pubmed	Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.	LIMA1 BSG GCC2 AHCY SLMAP VPS13B PCM1 ITPR1 KPNB1	1.85e-05	568	91	9	37774976
Pubmed	Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.	DNHD1 MID1 RNF213 TLN2 POLQ NLRP5	1.86e-05	208	91	6	33230847
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	DHX15 DNHD1 CAD BSG KIAA0586 AHCY EIF5B CASP7 PSMD1 TLN2 PUM1 ATAD2 LANCL2 KPNB1	1.97e-05	1425	91	14	30948266
Pubmed	Gene-dosage-sensitive genetic interactions between inversus viscerum (iv), nodal, and activin type IIB receptor (ActRIIB) genes in asymmetrical patterning of the visceral organs along the left-right axis.	NODAL DNAH11	2.03e-05	3	91	2	12112458
Pubmed	MID1 and MID2 homo- and heterodimerise to tether the rapamycin-sensitive PP2A regulatory subunit, alpha 4, to microtubules: implications for the clinical variability of X-linked Opitz GBBB syndrome and other developmental disorders.	MID2 MID1	2.03e-05	3	91	2	11806752
Pubmed	The schlafen family of proteins and their regulation by interferons.	SLFN12L SLFN12	2.03e-05	3	91	2	23570387
Pubmed	Schlafen-1 causes a cell cycle arrest by inhibiting induction of cyclin D1.	SLFN12L SLFN12	2.03e-05	3	91	2	15946944
Pubmed	Sequence data and chromosomal localization of human type I and type II hair keratin genes.	KRT81 KRT86	2.03e-05	3	91	2	7556444
Pubmed	Hepatic posttranscriptional network comprised of CCR4-NOT deadenylase and FGF21 maintains systemic metabolic homeostasis.	CNOT6 CNOT6L	2.03e-05	3	91	2	30926667
Pubmed	CNOT6L couples the selective degradation of maternal transcripts to meiotic cell cycle progression in mouse oocyte.	CNOT6 CNOT6L	2.03e-05	3	91	2	30478191
Pubmed	Sequences and differential expression of three novel human type-II hair keratins.	KRT83 KRT86	2.03e-05	3	91	2	9084137
Pubmed	Conserved left-right asymmetry of nodal expression and alterations in murine situs inversus.	NODAL DNAH11	2.03e-05	3	91	2	8610013
Pubmed	Schlafen4+-MDSC in Helicobacter-induced gastric metaplasia reveals role for GTPases.	SLFN12L SLFN12	2.03e-05	3	91	2	37334372
Pubmed	The role of MATER in endoplasmic reticulum distribution and calcium homeostasis in mouse oocytes.	ITPR1 NLRP5	2.03e-05	3	91	2	24374158
Pubmed	Gli1 deletion prevents Helicobacter-induced gastric metaplasia and expansion of myeloid cell subsets.	SLFN12L SLFN12	2.03e-05	3	91	2	23520544
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	ZC3H7A SETDB1 TUT4 CNOT6L MYCBP2 MID1 RNF213 SH3BP5L PUM1 PCM1	2.25e-05	733	91	10	34672954
Pubmed	SENP3 regulates the global protein turnover and the Sp1 level via antagonizing SUMO2/3-targeted ubiquitination and degradation.	DHX15 CUL3 PYGB KPNB1	2.47e-05	64	91	4	26511642
Pubmed	Genomic variants in an inbred mouse model predict mania-like behaviors.	CAD ZNFX1 DNAH11	2.95e-05	23	91	3	29768498
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	GSTM3 NRBP1 ZC3H7A CAD NUMBL MYCBP2 BSG P3H1 SLMAP EIF5B RB1CC1 VPS13B PCM1 ITPR1	3.14e-05	1487	91	14	33957083
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	DHX15 DNHD1 LIMA1 CAD PPP1R12A VPS13B	3.60e-05	234	91	6	36243803
Pubmed	Molecular motors: the driving force behind mammalian left-right development.	KIF3A DNAH11	4.05e-05	4	91	2	10652513
Pubmed	Identification of a novel left-right asymmetrically expressed gene in the mouse belonging to the BPI/PLUNC superfamily.	NODAL DNAH11	4.05e-05	4	91	2	14745963
Pubmed	FGF-induced vesicular release of Sonic hedgehog and retinoic acid in leftward nodal flow is critical for left-right determination.	KIF3A DNAH11	4.05e-05	4	91	2	15889083
Pubmed	Left-right development: the roles of nodal cilia.	KIF3A DNAH11	4.05e-05	4	91	2	10704402
Pubmed	MID1, mutated in Opitz syndrome, encodes an ubiquitin ligase that targets phosphatase 2A for degradation.	MID2 MID1	4.05e-05	4	91	2	11685209
Pubmed	Three types of cilia including a novel 9+4 axoneme on the notochordal plate of the rabbit embryo.	KIF3A DNAH11	4.05e-05	4	91	2	17061268
Pubmed	The Hsp40 family chaperone protein DnaJB6 enhances Schlafen1 nuclear localization which is critical for promotion of cell-cycle arrest in T-cells.	SLFN12L SLFN12	4.05e-05	4	91	2	18373498
Pubmed	An Slfn2 mutation causes lymphoid and myeloid immunodeficiency due to loss of immune cell quiescence.	SLFN12L SLFN12	4.05e-05	4	91	2	20190759
Pubmed	Schlafen 4-expressing myeloid-derived suppressor cells are induced during murine gastric metaplasia.	SLFN12L SLFN12	4.05e-05	4	91	2	27427984
Pubmed	Characterization and chromosomal localization of human hair-specific keratin genes and comparative expression during the hair growth cycle.	KRT81 KRT86	4.05e-05	4	91	2	9457912
Pubmed	Deadenylase-dependent mRNA decay of GDF15 and FGF21 orchestrates food intake and energy expenditure.	CNOT6 CNOT6L	4.05e-05	4	91	2	35385705
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	CAD TUT4 MYCBP2 BSG PYGB PSMD1 TLN2 ZNFX1 UNC13A PCM1 WNK2 ITPR1	4.19e-05	1139	91	12	36417873
Pubmed	Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.	ODF2L SDCCAG8 KIAA0586 ODF2 PCM1	4.23e-05	146	91	5	21399614
Pubmed	MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.	CAD MYCBP2 BSG SDCCAG8 RB1CC1 ODF2 KIF3A	4.45e-05	358	91	7	32460013
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	DHX15 CUL3 LIMA1 CAD LRRIQ1 MYCBP2 PPP1R12A MID1 AHCY EIF5B PSMD1 KPNB1	4.56e-05	1149	91	12	35446349
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	DHX15 GSTM3 CAD MYCBP2 AHCY EIF5B PYGB PSMD1 MYO16 KPNB1	5.06e-05	807	91	10	30575818
Pubmed	Cul3-KLHL20 E3 ubiquitin ligase plays a key role in the arms race between HIV-1 Nef and host SERINC5 restriction.	CUL3 MID2 MYCBP2	5.41e-05	28	91	3	35474067
Pubmed	Proteomic analysis identifies novel binding partners of BAP1.	CAD RB1CC1 LANCL2 KPNB1	5.96e-05	80	91	4	34591877
Pubmed	Subcellular localization of the Schlafen protein family.	SLFN12L SLFN12	6.74e-05	5	91	2	18355440
Pubmed	Monocilia in the embryonic mouse heart suggest a direct role for cilia in cardiac morphogenesis.	KIF3A DNAH11	6.74e-05	5	91	2	18729223
Pubmed	Schlafen-8 is essential for lymphatic endothelial cell activation in experimental autoimmune encephalomyelitis.	SLFN12L SLFN12	6.74e-05	5	91	2	29528433
Pubmed	Conversion of the LIMA1 tumour suppressor into an oncogenic LMO-like protein by API2-MALT1 in MALT lymphoma.	MALT1 LIMA1	6.74e-05	5	91	2	25569716
Pubmed	The paternal gene of the DDK syndrome maps to the Schlafen gene cluster on mouse chromosome 11.	SLFN12L SLFN12	6.74e-05	5	91	2	16172501
Pubmed	Determination of left/right asymmetric expression of nodal by a left side-specific enhancer with sequence similarity to a lefty-2 enhancer.	NODAL DNAH11	6.74e-05	5	91	2	10385627
Pubmed	The structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4-NOT deadenylase complex.	CNOT6 CNOT6L	6.74e-05	5	91	2	22977175
Pubmed	Expression and regulatory effects of murine Schlafen (Slfn) genes in malignant melanoma and renal cell carcinoma.	SLFN12L SLFN12	6.74e-05	5	91	2	24089532
Pubmed	Cnot8 eliminates naïve regulation networks and is essential for naïve-to-formative pluripotency transition.	CNOT6 CNOT6L	6.74e-05	5	91	2	35390160
Pubmed	ISG15 Connects Autophagy and IFN-γ-Dependent Control of Toxoplasma gondii Infection in Human Cells.	DHX15 CAD KRT81 PPP1R12A RNF213 PCM1	7.63e-05	268	91	6	33024031
Pubmed	ARMC5 is part of an RPB1-specific ubiquitin ligase implicated in adrenal hyperplasia.	CUL3 CAD BSG PSMD1 KPNB1	7.79e-05	166	91	5	35687106
Pubmed	mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.	DHX15 LIMA1 CAD PPP1R12A PUM1 KPNB1	8.61e-05	274	91	6	34244482
Pubmed	Calpain activity is negatively regulated by a KCTD7-Cullin-3 complex via non-degradative ubiquitination.	CUL3 CAD KPNB1	8.93e-05	33	91	3	36964131
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	ZC3H7A LIMA1 PDE6A BSG PPP1R12A ANKRD30A EIF5B PSMD1 CFAP74 ODF2 POLQ RBFA KPNB1	9.59e-05	1442	91	13	35575683
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	DHX15 GSTM3 LIMA1 CAD BSG PPP1R12A AHCY EIF5B PSMD1 LANCL2 KIF3A KPNB1	9.92e-05	1247	91	12	27684187
Pubmed	Essential functions of the CNOT7/8 catalytic subunits of the CCR4-NOT complex in mRNA regulation and cell viability.	CNOT6 CNOT6L	1.01e-04	6	91	2	31924127
Pubmed	Kif3a interacts with Dynactin subunit p150 Glued to organize centriole subdistal appendages.	ODF2 KIF3A	1.01e-04	6	91	2	23386061
Pubmed	XAF1 prevents hyperproduction of type I interferon upon viral infection by targeting IRF7.	CUL3 XAF1	1.01e-04	6	91	2	36394357
Interaction	PCM1 interactions	CUL3 ODF2L MYCBP2 KRT81 GCC2 KRT83 KRT86 KIAA0586 RB1CC1 ODF2 PCM1	3.67e-06	434	90	11	int:PCM1
Interaction	KCNA3 interactions	DHX15 DNHD1 CAD NUMBL BSG MID1 AHCY EIF5B RNF213 PSMD1 TLN2 POLQ LANCL2 KPNB1 NLRP5	6.73e-06	871	90	15	int:KCNA3
Interaction	CEP192 interactions	CUL3 CNOT6L SDCCAG8 SLMAP ODF2 PCM1 KPNB1	2.45e-05	192	90	7	int:CEP192
Interaction	OFD1 interactions	KRT81 KRT83 KRT86 SDCCAG8 SLMAP TRAK2 RB1CC1 ODF2 PCM1	2.49e-05	347	90	9	int:OFD1
Interaction	FAM83D interactions	CUL3 POLR1E KRT81 KRT83 TRAK2	3.30e-05	82	90	5	int:FAM83D
Interaction	TNRC6C interactions	CNOT6 CUL3 ZC3H7A CNOT6L ODF2 PUM1	3.59e-05	138	90	6	int:TNRC6C
Interaction	KRT19 interactions	CUL3 ODF2L KRT81 GCC2 KRT83 KRT86 RB1CC1 PCM1	3.83e-05	282	90	8	int:KRT19
Interaction	PPP1CB interactions	DHX15 CUL3 NRBP1 LIMA1 CAD MYCBP2 PPP1R12A RNF213 RB1CC1 KPNB1	4.59e-05	469	90	10	int:PPP1CB
Interaction	EXOC4 interactions	SETDB1 BSG KRT81 KRT83 KRT86 ODF2 PCM1	4.75e-05	213	90	7	int:EXOC4
Interaction	CAPZB interactions	CNOT6 DHX15 CUL3 NRBP1 LIMA1 CAD CNOT6L BSG PPP1R12A AHCY VPS26A PUM1 PCM1 ITPR1 KPNB1	5.89e-05	1049	90	15	int:CAPZB
Interaction	ARHGAP24 interactions	DHX15 CUL3 LIMA1 CAD P3H1 PPP1R12A PYGB PSMD1 WNK2 KPNB1	6.18e-05	486	90	10	int:ARHGAP24
Interaction	BTG3 interactions	NRBP1 SETDB1 CNOT6L MYCBP2 KIF3A	7.78e-05	98	90	5	int:BTG3
Interaction	YTHDF2 interactions	CNOT6 CUL3 ZC3H7A TUT4 CNOT6L BSG RB1CC1 PUM1	7.78e-05	312	90	8	int:YTHDF2
Interaction	ACOT9 interactions	CUL3 NRBP1 SETDB1 POLR1E MYO16 PCM1	9.70e-05	165	90	6	int:ACOT9
Interaction	GARRE1 interactions	CNOT6 CUL3 ZC3H7A CNOT6L RB1CC1 PUM1	1.04e-04	167	90	6	int:GARRE1
Interaction	COP1 interactions	CUL3 CAD LRRIQ1 MYCBP2 RNF213 PYGB RB1CC1 LANCL2	1.05e-04	326	90	8	int:COP1
Interaction	KXD1 interactions	MID2 KRT81 GCC2 SLMAP VPS26A TRAK2	1.14e-04	170	90	6	int:KXD1
Interaction	USP11 interactions	DHX15 CUL3 SETDB1 LIMA1 CAD MYCBP2 BSG PPP1R12A PSMD1 KPNB1	1.45e-04	539	90	10	int:USP11
Interaction	TEX101 interactions	GSTM3 CUL3 PDE6A BSG PYGB PSMD1 KPNB1	1.46e-04	255	90	7	int:TEX101
Cytoband	12q13	LIMA1 KRT81 KRT83 KRT86	1.27e-05	71	91	4	12q13
Cytoband	1p35.2	PUM1 SPOCD1	4.58e-04	16	91	2	1p35.2
GeneFamily	Keratins, type II	KRT81 KRT83 KRT86	7.40e-05	27	55	3	609
GeneFamily	Schlafen family	SLFN12L SLFN12	1.89e-04	7	55	2	1110
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	PPP1R12A RB1CC1 SPOCD1 MYO16 ITPR1	2.21e-04	181	55	5	694
GeneFamily	CCR4-NOT transcription complex	CNOT6 CNOT6L	4.91e-04	11	55	2	1023
GeneFamily	Ring finger proteins\|Tripartite motif containing\|ARF GTPase family	TRIM51 MID2 MID1	3.03e-03	95	55	3	59
Coexpression	HAMAI_APOPTOSIS_VIA_TRAIL_UP	LIMA1 TUT4 MYCBP2 GCC2 MID1 SLMAP GOLIM4 EIF5B VPS26A RB1CC1 POLQ ATAD2 PCM1 KIF3A ITPR1	7.64e-09	656	91	15	M18979
Coexpression	THAKAR_PBMC_INACTIVATED_INFLUENZA_AGE_21_30YO_NONRESPONDER_28DY_UP	CNOT6 SLMAP SH3BP5L VPS26A TRAK2 RB1CC1 PCM1	2.55e-06	174	91	7	M40888
Coexpression	GSE8868_SPLEEN_VS_INTESTINE_CD11B_POS_CD11C_NEG_DC_UP	CCDC28B PDIK1L SDCCAG8 SLMAP RIOK3 PUM1 VPS13B	6.38e-06	200	91	7	M5772
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	DHX15 MALT1 SETDB1 TUT4 MYCBP2 GCC2 PPP1R12A MID1 RB1CC1 PUM1 MBOAT2 VPS13B ITPR1	8.02e-06	856	91	13	M4500
Coexpression	CAIRO_HEPATOBLASTOMA_CLASSES_UP	CNOT6 CAD BSG AHCY EIF5B RIOK3 RB1CC1 ODF2 LANCL2 PCM1 KPNB1	8.98e-06	612	91	11	M4772
Coexpression	GSE41867_DAY6_EFFECTOR_VS_DAY30_EXHAUSTED_CD8_TCELL_LCMV_CLONE13_UP	SLFN12L MYCBP2 P3H1 CASP7 ZNFX1 ITPR1	7.12e-05	200	91	6	M9489
Coexpression	GSE45739_NRAS_KO_VS_WT_ACD3_ACD28_STIM_CD4_TCELL_UP	DHX15 POLR1E KRT86 ZNFX1 ATP8B2 NLRP5	7.12e-05	200	91	6	M9881
Coexpression	GSE35825_IFNA_VS_IFNG_STIM_MACROPHAGE_DN	SCN3A RB1CC1 ATP8B2 PCM1 RBFA KPNB1	7.12e-05	200	91	6	M8656
Coexpression	GSE21380_NON_TFH_VS_GERMINAL_CENTER_TFH_CD4_TCELL_DN	CUL3 PPP1R12A EIF5B VPS26A ATP8B2 ITPR1	7.12e-05	200	91	6	M7505
Coexpression	BENPORATH_CYCLING_GENES	MYCBP2 MID1 KIAA0586 GAS6 ZNFX1 ODF2 POLQ ATAD2 ITPR1 KPNB1	8.46e-05	648	91	10	M8156
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#2	ODF2L TUT4 GCC2 KIAA0586 SLMAP ODF2 POLQ PCM1 KIF3A	6.29e-06	311	89	9	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K2
ToppCell	mild-CD4+_Tcm\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	MALT1 SLFN12L ODF2L CNOT6L GCC2 XAF1 ANKRD36 ATP8B2	7.90e-09	199	91	8	06c8a0e39f7a33736548f04a5e2263334c8541cf
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ODF2L TUT4 CNOT6L GCC2 IGHM ANKRD36 PCM1	1.53e-07	195	91	7	ed5f772c82d4dfd1c8735224446ec9feae3fb8c2
ToppCell	systemic_lupus_erythematosus-flare\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	TUT4 GCC2 PPP1R12A RNF213 XAF1 ANKRD36 PCM1	1.70e-07	198	91	7	4c93ee921d56132d80832d8e94563f32ccf13bbc
ToppCell	(11)_FOXN4+-(2)_GFP_FOXI1\|(11)_FOXN4+ / shred by cell type by condition	ODF2L LRRIQ1 MYCBP2 GCC2 PSMD1 TRAK2 RB1CC1	1.70e-07	198	91	7	76d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCell	COVID-19_Moderate\|World / disease group, cell group and cell class	SLFN12L ODF2L TUT4 GCC2 IGHM RNF213 XAF1	1.76e-07	199	91	7	952fac67588ad5676f5939e3c7f8bac803c27064
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	SLFN12L TUT4 CNOT6L RNF213 ANKRD36 PCM1	1.41e-06	171	91	6	2e9a20f8980b78325c52065a9c14ab3656267c05
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1\|TCGA-Pancreas / Sample_Type by Project: Shred V9	CNOT6 GCC2 PPP1R12A SLMAP GOLIM4 VPS13B	2.29e-06	186	91	6	03db813598b67b1e08f759758a1c2023396921fa
ToppCell	droplet-Marrow-nan-3m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LIMA1 GCC2 SLMAP GOLIM4 CASP7 ATAD2	2.37e-06	187	91	6	14c239af77116d28d511dea754b6150d20488080
ToppCell	COVID_non-vent-Lymphocytic\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	SLFN12L TUT4 GCC2 IGHM ANKRD36 ATP8B2	3.19e-06	197	91	6	c672915f8c8c1e948d251f6eaf9f84a5600c1193
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SLFN12L ODF2L RNF213 ANKRD36 VPS13B PCM1	3.39e-06	199	91	6	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	(10)_Ciliated-(2)_GFP_FOXI1\|(10)_Ciliated / shred by cell type by condition	ODF2L LRRIQ1 GCC2 EIF5B ANKRD36 RB1CC1	3.39e-06	199	91	6	61b1ed2db71b96157b92b7535d1955a4033098da
ToppCell	healthy_donor-Lymphocytic\|healthy_donor / Disease condition, Lineage, Cell class and subclass	SLFN12L TUT4 CNOT6L RNF213 ANKRD36 ATP8B2	3.39e-06	199	91	6	2841e16d54acd344ba454f024e285c28abc37319
ToppCell	(03)_KRT6B+-(2)_GFP_FOXI1\|(03)_KRT6B+ / shred by cell type by condition	LIMA1 GCC2 EIF5B XAF1 ANKRD36 RB1CC1	3.39e-06	199	91	6	c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCell	IIH-CD8-proli_CD4\|IIH / Condition, Cell_class and T cell subcluster	GSTM3 CAD PDE6A P3H1 PYGB	1.25e-05	146	91	5	7fa6e35def3f7cffbee1e1c2f10b523bab678e14
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC-Late_airway_SMC\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	PPP1R12A SLMAP SPOCD1 NODAL DNAH11	2.12e-05	163	91	5	1e8730d75cccf7292010683ab4e81a69d8e3bfa9
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GCC2 SCN3A ABCC12 ITPR1 DNAH11	3.15e-05	177	91	5	1dc69c661e70e7e22bd9d7cf953eb638da9fd43c
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GCC2 SCN3A ABCC12 ITPR1 DNAH11	3.15e-05	177	91	5	426a9845df7fd13b02e744532c336c60bc4d4a22
ToppCell	367C-Lymphocytic-ILC-ILC-2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	HSPBAP1 KRT81 P3H1 IGHM ANKRD36	3.32e-05	179	91	5	5aa8465e943b6b666c7f8b1937fcc3764bfe91f6
ToppCell	FF-Differ-KC\|World / shred by cell class for mouse tongue	KRT81 KRT83 KRT86 MBOAT2 DNAH11	3.32e-05	179	91	5	1526a130565a97c291a25a7a988089bffc1515c1
ToppCell	T_cells-ISG-high_CD4+_T_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	SLFN12L ODF2L RNF213 ZNFX1 XAF1	4.20e-05	188	91	5	6f8946d4710f6e32c937213f99b790b098b8819c
ToppCell	Striatum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Ccnd1_(Mural.Rgs5Acta2.Ccnd1)\|Striatum / BrainAtlas - Mouse McCarroll V32	PDE6A ADAMTS15 MAP3K7CL NODAL	4.51e-05	96	91	4	d98df92856840602a82d3f050bf0a1543445cac0
ToppCell	Striatum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Ccnd1_(Mural.Rgs5Acta2.Ccnd1)-\|Striatum / BrainAtlas - Mouse McCarroll V32	PDE6A ADAMTS15 MAP3K7CL NODAL	4.51e-05	96	91	4	bf62c29da66aa3eefdc59337dfb3cd0467f04f10
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SLFN12L TRBV28 TUT4 CNOT6L GCC2	4.53e-05	191	91	5	696921a4f160b6b55698652488ed781e855e5e51
ToppCell	human_hepatoblastoma-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	TUT4 GCC2 RB1CC1 PUM1 PCM1	4.64e-05	192	91	5	916fbec1c7ab7969bda711886ac88e877e30c280
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	OPTC PPP1R12A SLMAP ADAMTS15 MAP3K7CL	4.64e-05	192	91	5	26d9207e72bbef5e0046de511e2c9ff752b726f3
ToppCell	10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC-A\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	BSG MAP3K7CL SPOCD1 LANCL2 DNAH11	4.64e-05	192	91	5	2dee0402e97e48157e0bc01bcc8034f1645dfb7b
ToppCell	5'-Adult-SmallIntestine-Hematopoietic-T_cells-TRGV2_gdT\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLFN12L ODF2L CNOT6L KRT81 KRT86	4.76e-05	193	91	5	544de0988510cc57744710d7cafe07aa27a0b99d
ToppCell	ASK428-Immune-T_cell\|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq	SLFN12L TRBV28 ODF2L RNF213 ATP8B2	4.76e-05	193	91	5	bca9bf941193feea8ed56735041513185c165135
ToppCell	human_hepatoblastoma\|World / Sample and Cell Type and Tumor Cluster (all cells)	TUT4 GCC2 RB1CC1 PUM1 PCM1	4.76e-05	193	91	5	e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_T\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ODF2L TUT4 GCC2 ANKRD36 PCM1	4.99e-05	195	91	5	53528e5788083bce5a8d4611ab3808878e6a9cd3
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SLFN12L GCC2 RNF213 ANKRD36 PCM1	5.24e-05	197	91	5	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	mild-low-quality_cells\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SLFN12L ODF2L RNF213 ANKRD36 MYO16	5.24e-05	197	91	5	e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCell	Control-PLT_4\|Control / Disease Group and Platelet Clusters	ZC3H7A PDIK1L PPP1R12A RB1CC1 VPS13B	5.37e-05	198	91	5	387fd3037fd52e4d4c42de0588767e58af228b59
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ODF2L TUT4 CNOT6L GCC2 IGHM	5.37e-05	198	91	5	a3bd099ef0e606c2da690a6fcf6f79e9360c9c9f
ToppCell	(02)_MMP9/10+-(2)_GFP_FOXI1\|(02)_MMP9/10+ / shred by cell type by condition	LIMA1 GCC2 GOLIM4 XAF1 RB1CC1	5.50e-05	199	91	5	18a7f9ced4364f45b184bd529f32ef02c27779d3
ToppCell	(01)_IL1RL1+-(2)_GFP_FOXI1\|(01)_IL1RL1+ / shred by cell type by condition	LIMA1 GCC2 GOLIM4 EIF5B RB1CC1	5.50e-05	199	91	5	a2f7d0cabf35b80fe239fae34a77bf9344d5d743
ToppCell	LPS_anti-TNF-Hematopoietic_Myeloid-Dendritic_cells-pDC\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	IGHM GAS6 ANKRD30A PYGB ATP8B2	5.63e-05	200	91	5	6a34e07e6d77fe3fdd9ff44c4b1e46a023f6d6a2
ToppCell	COVID-19-COVID-19_Severe-Others-RBC\|COVID-19_Severe / Disease, condition lineage and cell class	BSG RIOK3 TLN2 TRAK2 MBOAT2	5.63e-05	200	91	5	308f74e7e13ecc6d133c219c42cc8895a96644c8
ToppCell	mild-gd_T\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SLFN12L ODF2L CNOT6L RNF213 XAF1	5.63e-05	200	91	5	109f673a4967ffa52270a0b4f818b3461288db44
ToppCell	mild-CD8+_T_naive\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SLFN12L GCC2 XAF1 ATP8B2 PCM1	5.63e-05	200	91	5	c825320599a61a4c629d736f5c0fd6f1f405540a
ToppCell	droplet-Tongue-nan-24m-Epithelial-nan\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT81 KRT83 KRT86 TRAK2	6.17e-05	104	91	4	a4ae3cae44aac8b6e0d14896f9acab44f0cc97c4
ToppCell	Cerebellum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3\|Cerebellum / BrainAtlas - Mouse McCarroll V32	HSPBAP1 CFAP74 MAP3K7CL NODAL	1.64e-04	134	91	4	8a3acf32cabc37b49d6488d43cdaae7cec79d119
ToppCell	Cerebellum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Acta2Rgs5.Rgs5_(Mural.Acta2Rgs5.Rgs5)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	HSPBAP1 CFAP74 MAP3K7CL NODAL	1.64e-04	134	91	4	1fa13185a4dfb4563473184c0c4f449011d88631
ToppCell	Cerebellum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Acta2Rgs5.Rgs5_(Mural.Acta2Rgs5.Rgs5)-\|Cerebellum / BrainAtlas - Mouse McCarroll V32	HSPBAP1 CFAP74 MAP3K7CL NODAL	1.64e-04	134	91	4	1ab99a22d0d7657f62f8ea7d96bb24e88de54fd4
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GDPD1 PDIK1L MID1 AIFM3	1.79e-04	137	91	4	e9b88ad86b75454a8292a94879c5b665adc42744
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Diffuse-5\|TCGA-Stomach / Sample_Type by Project: Shred V9	LRRIQ1 KRT81 KRT86 SPOCD1	1.89e-04	139	91	4	849e4c060c9cf9eb7962caf5b169e72da4d85e70
ToppCell	Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Nxph3-Excitatory_Neuron.Slc17a7-Slc17a6.Nxph3-Cbln2-Htr2c_(Deep_layer_subiculum)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	KRT81 KRT86 ABCC12	2.16e-04	57	91	3	35494ca30bdafb4c175d74f0b4892098411784b0
ToppCell	3'_v3-Lung-Lymphocytic_T_CD4-T_CD4/CD8\|Lung / Manually curated celltypes from each tissue	SLFN12L TUT4 CNOT6L ANKRD36	2.60e-04	151	91	4	999c11d19b61d6b130ad5e623afa83cbdfe13cdd
ToppCell	367C-Lymphocytic-CD4_T-cell-Treg_cell_4\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	LIMA1 SLFN12 ANKRD36 UNC13A	2.66e-04	152	91	4	eb7ff36792c3c54ac88cfe976f84016b70b1a1d7
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Degenerative_Distal_Convoluted_Tubule_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GSTM3 CNOT6L BSG SCN3A	2.73e-04	153	91	4	98670bbce4a770af244f033cdd2d54db57200ca8
ToppCell	COVID-19_Moderate-multiplets\|World / disease group, cell group and cell class	SLFN12L IGHM RNF213 ANKRD36	2.94e-04	156	91	4	afdc025fa75e7926b1cc182c4a33654a2186abb1
ToppCell	Severe-B_naive-1\|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)	TUT4 IGHM SCN3A ITPR1	3.16e-04	159	91	4	2881b054bbeb479221ee3c38bbd9b0815b123579
ToppCell	343B-Myeloid-Dendritic-cDC1\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	GDPD1 PDIK1L SCN3A AIFM3	3.31e-04	161	91	4	537a1d86de99a493b0345ca0f760994260e97049
ToppCell	facs-Thymus-Epithelium-3m-Epithelial-epithelial_cell_of_thymus\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OPTC LIMA1 MID2 KRT86	3.39e-04	162	91	4	3dc39db0d5f6f3d7bcc312a6bce7aaeb914138d1
ToppCell	facs-Thymus-Epithelium-3m-Epithelial\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OPTC LIMA1 MID2 KRT86	3.39e-04	162	91	4	0a7138266054ea5954649c8b61ef93905d56b068
ToppCell	facs-Thymus-Epithelium-3m-Epithelial-TECs\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OPTC LIMA1 MID2 KRT86	3.39e-04	162	91	4	25323785dd33337bcefd05958a4a1a208a9ceb04
ToppCell	3'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SLFN12L KRT81 KRT86 VPS13B	3.47e-04	163	91	4	e6213900f56257fe38ac7852351bea0340294be0
ToppCell	3'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SLFN12L KRT81 KRT86 VPS13B	3.47e-04	163	91	4	ed7319185c1ec384444309bb8be95691a0c2091c
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c12-MKI67-TYROBP\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	KRT81 KRT86 GOLIM4 POLQ	3.47e-04	163	91	4	466c8129852a5b16cd9fcc6b79e799abc21bb21a
ToppCell	3'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SLFN12L KRT81 KRT86 VPS13B	3.47e-04	163	91	4	ef35d7ff09aa364734fea7fdaab6260c0a3fbf09
ToppCell	PND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_prolif\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MALT1 POLR1E ODF2 ATAD2	3.55e-04	164	91	4	5621c2e3fae84d5a2e4f1595e454bcb3a2b3f93c
ToppCell	5'-Adult-Appendix-Hematopoietic-T_cells-Activated_CD8_T\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLFN12L CNOT6L RNF213 KIF3A	3.55e-04	164	91	4	24fdea5113d92b96f56b06dd2449910a3c785e69
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Ciliated_2\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	DNHD1 MID2 CFAP74 DNAH11	3.64e-04	165	91	4	731147b4337fd0de4383dc8170b4f9ccd98caec6
ToppCell	PND01-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_prolif\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IGHM SDCCAG8 POLQ ATAD2	3.64e-04	165	91	4	66f0364098d82629aa2ec1dfe0c5ad23de7c2c12
ToppCell	PBMC-Severe-Lymphocyte-B-B_cell-B_naive-B_naive-1\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TUT4 IGHM SCN3A ITPR1	3.64e-04	165	91	4	fead3f2032f8fa5f7f0159a4434989b3d65debbb
ToppCell	10x5'-Liver-Hematopoietic_progenitors\|Liver / Manually curated celltypes from each tissue	MID1 POLQ ATAD2 MBOAT2	3.72e-04	166	91	4	ae967570248cf86ca3ddf55e33bcbb3e4e3684bc
ToppCell	10x5'-Liver-Hematopoietic_progenitors-Cycling_pre-Myeloid-2\|Liver / Manually curated celltypes from each tissue	MID1 POLQ ATAD2 MBOAT2	3.72e-04	166	91	4	a176e87aa6eec81d1fb79a028f759182d11b567d
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SLFN12L ODF2L ANKRD36 WNK2	3.81e-04	167	91	4	83969c36ac44b96afc9aa09400a99fa2b487f7ff
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Lgr5+_amplifying_undifferentiated_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PYGB TLN2 LANCL2 DNAH11	3.89e-04	168	91	4	d69452e2cfeb74023b5cf3d09064d7dcad0008ec
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ODF2L LRRIQ1 CFAP74 DNAH11	3.98e-04	169	91	4	14aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCell	Int-URO-Lymphocyte-T_NK-dnT\|Int-URO / Disease, Lineage and Cell Type	LIMA1 CAD NUMBL KIF3A	4.25e-04	172	91	4	e70299573da1679d6d286c3a43699cbff76e207d
ToppCell	367C-Lymphocytic-ILC-ILC-2\|367C / Donor, Lineage, Cell class and subclass (all cells)	KRT81 IGHM KRT86 ANKRD36	4.35e-04	173	91	4	0451450605521fecb27a958628870d268adfb023
ToppCell	Ionocyte-iono-2\|World / Class top	SCN3A CASP7 MBOAT2 UNC13A	4.35e-04	173	91	4	e5ec28ccc5e048fd98de4c876e5c53b866b66228
ToppCell	10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_cytotoxic-D\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	GDPD1 ODF2L SLMAP POLQ	4.54e-04	175	91	4	a3f8c54c77bce9b035a4835945ab341909be4946
ToppCell	metastatic_Brain-T/NK_cells-Exhausted_Tfh\|metastatic_Brain / Location, Cell class and cell subclass	CNOT6L CCDC28B KRT81 KRT86	4.54e-04	175	91	4	b732c6a423c28856211002107d8c611dcfb6f265
ToppCell	facs-Heart-RV-18m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCN3A CFAP74 MAP3K7CL WNK2	4.54e-04	175	91	4	d8e385320f554d974538b7cdc4f8e4767f1455f2
ToppCell	facs-Heart-RV-18m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCN3A CFAP74 MAP3K7CL WNK2	4.54e-04	175	91	4	cf15465855602ba135752c18755e3e058dbd42ec
ToppCell	PBMC-Control-Lymphocyte-B-B_cell-B_naive-B_naive-1\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IGHM SCN3A EFCAB13 ITPR1	4.64e-04	176	91	4	ad05dd934f4ac2e656b3455de091f4c8772de6c8
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Degenerative_Distal_Convoluted_Tubule_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GSTM3 CNOT6L SCN3A ITPR1	4.74e-04	177	91	4	dc846d0feb94d4c289553cc3ac9dac81d10409cb
ToppCell	facs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l39\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PDE6A PPP1R12A SCN3A MAP3K7CL	4.74e-04	177	91	4	928118b0ed120ec01c7d753ce523ab609ac24e5f
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_T-T4_naive-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	GSTM3 ODF2L TUT4 GCC2	4.74e-04	177	91	4	db6de487ef7976b444afadbf3ac60b3259925566
ToppCell	5'-GW_trimst-2-LargeIntestine-Hematopoietic-T_cells-LTi-like_NCR+_ILC3\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLFN12L KRT81 KRT86 ANKRD36	4.84e-04	178	91	4	0b59e3d75b143bd7bf91a7800a49699c51e68c5a
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_T-T4_reg-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ODF2L GCC2 ANKRD36 ATP8B2	4.84e-04	178	91	4	90dedb3cef9b01907b9f8eec64218d6d2072be1f
ToppCell	metastatic_Brain-T/NK_cells-Exhausted_Tfh\|T/NK_cells / Location, Cell class and cell subclass	LIMA1 CCDC28B KRT86 PYGB	4.84e-04	178	91	4	9a3581a0158dfa5a1cc942f8c532afb5e38b272a
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_T-T4_reg\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ODF2L GCC2 ANKRD36 ATP8B2	4.84e-04	178	91	4	d6312286bf6cc5b107ccd7adb583d9667d4e1d21
ToppCell	T_cells-ISG-high_CD4+_T_cells\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	ODF2L RNF213 ZNFX1 XAF1	4.94e-04	179	91	4	af35ef8a7768cee0c2af0590e5bec35cee6a4714
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-hematologic-erythrocytic-erythrocyte\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	BSG TLN2 TRAK2 MBOAT2	4.94e-04	179	91	4	dfefa4b7ae0ee50cf67e0f1938c682f08a03ec53
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-hematologic-erythrocytic\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	BSG TLN2 TRAK2 MBOAT2	4.94e-04	179	91	4	64672528f73ac0921f9c7df72e14ecbfac4d5270
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-hematologic\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	BSG TLN2 TRAK2 MBOAT2	4.94e-04	179	91	4	fa0dd87111d399649cdea55f2e610ebc169e8a56
ToppCell	3'-GW_trimst-1-LargeIntestine-Hematopoietic-T_cells\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLFN12L KRT81 KRT83 KRT86	4.94e-04	179	91	4	e717c0079b788a3703c0a450922bd5a2bdc322a0
ToppCell	3'-GW_trimst-1-LargeIntestine-Hematopoietic-T_cells-ILCP\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLFN12L KRT81 KRT83 KRT86	4.94e-04	179	91	4	dd3cf8fd10dc257d933a7f45860dc2e244c158b7
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Hematopoietic-T_cells-ILCP\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLFN12L KRT81 KRT83 KRT86	5.05e-04	180	91	4	ca7c316027e31559103b2cab1a2c0de993e42e95
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Hematopoietic-T_cells\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLFN12L KRT81 KRT83 KRT86	5.05e-04	180	91	4	eb26ba86fba26899e54c448afc25382ddc853013
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Lymphocytic-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BSG GAS6 EIF5B ANKRD36	5.05e-04	180	91	4	54e3f289a37d4cfbfca4fb284c3b52e9c7d9da97
ToppCell	10x5'v1-week_14-16-Lymphocytic_NK-T_NK-ILC_precursor\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	SLFN12L KRT81 KRT83 KRT86	5.05e-04	180	91	4	a999a6d219a8e58a8b63802ddf8c95ffaab9cfa0
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BSG GAS6 EIF5B ANKRD36	5.05e-04	180	91	4	bfc8568d57034dd9c9e07edae94479a48ca0706d
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LRRIQ1 WNT7B ADAMTS15 DNAH11	5.15e-04	181	91	4	6a6bd8e020cb0929b6ecdcb55d467ad24fecfaf0
ToppCell	droplet-Marrow-nan-3m-Myeloid-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TUT4 MYCBP2 GCC2 PCM1	5.26e-04	182	91	4	f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCell	T_cells-Resident_memory_CD8+_T_cells\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	KRT81 IGHM KRT86 GOLIM4	5.26e-04	182	91	4	111d434b89902ec11fb07f41b8ee1a98f3991b61
ToppCell	Cerebellum-Endothelial-MURAL-M1(Rgs5Acta2)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	P3H1 PPP1R12A MAP3K7CL NODAL	5.26e-04	182	91	4	da61e7cb2537c567968d8bd8baf537ecdff0ab18
Drug	Moroxidine hydrochloride [3160-91-6]; Down 200; 19.2uM; PC3; HG-U133A	DHX15 BSG P3H1 PYGB RIOK3 CFAP74 PUM1 PCM1	1.15e-06	197	90	8	1944_DN
Drug	Triamcinolone [124-94-7]; Down 200; 10.2uM; HL60; HG-U133A	CNOT6 MID2 PPP1R12A RIOK3 XAF1 RB1CC1 PCM1	1.33e-05	197	90	7	1395_DN
Drug	Dibucaine [85-79-0]; Down 200; 11.6uM; PC3; HG-U133A	CUL3 SETDB1 MID2 P3H1 EIF5B CASP7 RIOK3	1.42e-05	199	90	7	1889_DN
Drug	tebuquine	KRT81 KRT83	1.55e-05	2	90	2	CID000071991
Drug	3,5-di-O-galloylquinic acid	KRT81 KRT83	1.55e-05	2	90	2	CID000460896
Drug	melicopicine	KRT81 KRT83	1.55e-05	2	90	2	CID000101253
Disease	Beaded hair	KRT81 KRT83 KRT86	2.48e-08	3	87	3	cv:C0546966
Disease	MONILETHRIX	KRT81 KRT83 KRT86	2.48e-08	3	87	3	158000
Disease	monilethrix (is_implicated_in)	KRT81 KRT83 KRT86	2.48e-08	3	87	3	DOID:0050472 (is_implicated_in)
Disease	Monilethrix	KRT81 KRT83 KRT86	9.88e-08	4	87	3	C0546966
Disease	hair disease (is_implicated_in)	KRT81 KRT86	8.59e-06	2	87	2	DOID:421 (is_implicated_in)
Disease	Opitz GBBB syndrome (implicated_via_orthology)	MID2 MID1	1.28e-04	6	87	2	DOID:0080697 (implicated_via_orthology)
Disease	Ciliopathies	CCDC28B SDCCAG8 NODAL DNAH11	3.21e-04	110	87	4	C4277690
Disease	quality of life during menstruation measurement, dysmenorrheic pain measurement	RB1CC1 VPS13B	4.65e-04	11	87	2	EFO_0007889, EFO_0009366
Disease	diastolic blood pressure, systolic blood pressure	DHX15 ODF2L SDCCAG8 ADAMTS15 PSMD1 TLN2 MAP3K7CL PCM1	8.19e-04	670	87	8	EFO_0006335, EFO_0006336
Disease	Holoprosencephaly	PPP1R12A NODAL	1.14e-03	17	87	2	C0079541
Disease	Bardet-Biedl syndrome	CCDC28B SDCCAG8	1.28e-03	18	87	2	cv:C0752166
Disease	wellbeing measurement, alcohol consumption measurement	KIAA0586 GOLIM4 UNC13A	1.38e-03	74	87	3	EFO_0007869, EFO_0007878
Disease	receptive language perception	MALT1 KIF3A	1.42e-03	19	87	2	EFO_0005686
Disease	brain volume measurement	CNOT6L NUMBL KRT86 EFCAB13 ADAMTS15 PYGB DNAH11	1.90e-03	595	87	7	EFO_0006930
Disease	anxiety disorder (implicated_via_orthology)	SCN3A NODAL	1.91e-03	22	87	2	DOID:2030 (implicated_via_orthology)
Disease	gestational diabetes	NUMBL PPP1R12A	2.09e-03	23	87	2	EFO_0004593
Disease	brain cancer (implicated_via_orthology)	NUMBL VPS26A	2.67e-03	26	87	2	DOID:1319 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
HIEECVKQMGDILSQ	UNC13A	1311	Q9UPW8
EKVFLECVQDMDHEN	TRBV28	36	A0A5B6
KVMETEDLNLGHVCQ	C2orf16	696	Q68DN1
EMLNHATCKVNEAEE	SH3BP5L	171	Q7L8J4
AVCHVKDLENGQMRE	AIFM3	71	Q96NN9
ELQKDHCEQRTGKME	ANKRD30A	976	Q9BXX3
NGQVHEMSEELMELC	DNAH11	501	Q96DT5
MIEKLLSHGTNIEEC	ANKRD36	146	A6QL64
HISDENEGKEMCVLR	ATAD2	1281	Q6PL18
AHCEELEGQKLQEMV	DNHD1	3831	Q96M86
IRTVIQIHMCEEEEG	DHX15	336	O43143
VFNMPHDNVKVCEEV	ADAMTS15	366	Q8TE58
SLCHTVMSEEKNEGE	ATP8B2	491	P98198
EESRGMHVCEDAVKK	NUMBL	91	Q9Y6R0
LCGIDHEALNKQIME	RBFA	236	Q8N0V3
GQMESHLKELERVCD	ODF2L	456	Q9ULJ1
RVVMDGVISDHECQE	P3H1	471	Q32P28
CFVMLHADQDGEKLQ	RB1CC1	456	Q8TDY2
MENCLGESRHEVEKS	LIMA1	161	Q9UHB6
CEIHDGMFRKDEELT	MBOAT2	146	Q6ZWT7
TVLLDEVAEDMGKCH	MALT1	526	Q9UDY8
GEMSLAEVQCHLDKE	ITPR1	1796	Q14643
NEKNDEGVTLLHMAC	MYO16	216	Q9Y6X6
CEEMKATVIRHGETL	KRT86	301	O43790
QQMEEGLKTADPHDC	LANCL2	86	Q9NS86
HKAEQCEEEEAMTPR	HMGN2P46	36	Q86SG4
KNHLSGEICEMQTEE	PCM1	1991	Q15154
ETMQRDVFCDPEEHK	OPTC	281	Q9UBM4
HKDAVLEDCLVMPDQ	PDE6A	116	P16499
QHAVKIGTDMLELDC	GDPD1	61	Q8N9F7
IGTDMLELDCHITKD	GDPD1	66	Q8N9F7
RKHNMCGETEEEKIR	GSTM3	86	P21266
GTHLKEEDVRMACEA	NLRP5	846	P59047
ITIECSEKGIDGNMH	KIF3A	226	Q9Y496
MEGRHQEILVCQKRE	LRRIQ1	1286	Q96JM4
LMQCNIESVEEGVKH	NRBP1	446	Q9UHY1
NEMVRELDGHVLKCV	PUM1	951	Q14671
KQENTEVEEHLVMAG	GOLIM4	586	O00461
GNVCMRESHDKEEEK	OTOP1	501	Q7RTM1
KEELNVCNHMEVGQT	HSPBAP1	356	Q96EW2
KDVMQGTDEHVVCKV	IGHM	76	P01871
ALALMEIKVCDGQEH	GAS6	561	Q14393
INEEIERVMHCLDKS	CUL3	241	Q13618
MLQVKGDEDHVVSLC	POLQ	316	O75417
MCQIEASAKEHEAEI	GCC2	256	Q8IWJ2
HINEGETAMLVCKSE	BSG	231	P35613
EKQERTVMSHGCENF	C17orf80	321	Q9BSJ5
CSILEEHGKDLEIMQ	CASP7	246	P55210
METKVHLFCQAEENI	EFCAB13	1	Q8IY85
KESERHFIMQVVCEA	KPNB1	211	Q14974
EGCDNEEDLQMGIHK	HBP1	241	O60381
GKECSFEQLEHVREM	CCDC28B	111	Q9BUN5
HFEQMKDDAIVCNIG	AHCY	286	P23526
GRIREQEKKEEMECH	CFAP74	261	Q9C0B2
TMSEQERKHVDGCAI	CNOT6	271	Q9ULM6
CEEMKATVIRHGETL	KRT83	306	P78385
EQHCKEDSERLMEQQ	ODF2	276	Q5BJF6
DSEESMEVFKQHCQI	MAP3K7CL	51	P57077
EEILKMIEENSHCTF	POLR1E	241	Q9GZS1
VLLDHHKDMIVEECG	NODAL	331	Q96S42
EEQCVQHGRVHETMK	SDCCAG8	646	Q86SQ7
AHCEELRAQVMEVKA	EIF5B	851	O60841
NVIHLEECILQKDGM	PDIK1L	66	Q8N165
EGIVNKMFQRCLDDH	PSMD1	131	Q99460
EGVDHCMVKLDNDPQ	MYCBP2	1511	O75592
VIEIHEGNKIDSCMS	SCN3A	1036	Q9NY46
CDHVLVMENGKVIEF	ABCC12	1321	Q96J65
RHFIDEELEKMDCVQ	SETDB1	41	Q15047
IMSEQERKHVDGCAI	CNOT6L	271	Q96LI5
HDEVVCGRKNTARME	RIOK3	166	O14730
SCIKEVLCDHMVDGQ	RNF213	2496	Q63HN8
CLGMLHESQEEIKEL	TRAK2	336	O60296
VLEDRMQLECKCHGV	WNT7B	191	P56706
QHEGLKQLICEEMGS	SLFN12L	421	Q6IEE8
LSSEEQICGMHRETK	TRIM51	86	Q9BSJ1
CTHLKEMNERTQEEL	SLMAP	286	Q14BN4
THKGEVEIQRDMDQT	SPOCD1	736	Q6ZMY3
RGLMCLEHEDEKVNM	MID1	171	O15344
MEEHCKLEHQQVGCT	XAF1	46	Q6GPH4
VIEEGDCKRINMAHL	PYGB	431	P11216
LQHEGLKQLICEEMD	SLFN12	401	Q8IYM2
RMVDENCVGFDHTVK	CAD	781	P27708
ELRQEQDHCMHLEKI	MYH16	931	Q9H6N6
EQELHEGAKTLECTM	ZNFX1	726	Q9P2E3
NMGFHDKVLEDCNIV	ZC3H7A	101	Q8IWR0
NNSIKMEVGIEDCLH	VPS26A	161	O75436
EIEDLTCHNKDMLGN	VPS13B	296	Q7Z7G8
RIFQEHKNCGEMSEI	TLN2	281	Q9Y4G6
NTGDKMVECQLETHN	WNK2	1196	Q9Y3S1
RGITCLDHENEKVNM	MID2	191	Q9UJV3
DICMTLEGHENAEKL	TUT4	1011	Q5TAX3
EKENMEVSCHRGNVR	KIAA0586	351	Q9BVV6
CEEMKATVIRHGETL	KRT81	301	Q14533
ALHQACIDDNVDMVK	PPP1R12A	76	O14974