Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainDOCK_N

DOCK3 DOCK4

7.27e-055512PF16172
DomainDOCK_N

DOCK3 DOCK4

7.27e-055512IPR032376
DomainDOCK_C

DOCK3 DOCK4

3.96e-0411512IPR010703
DomainDHR-1_domain

DOCK3 DOCK4

3.96e-0411512IPR027007
DomainDHR_2

DOCK3 DOCK4

3.96e-0411512PS51651
DomainDHR_1

DOCK3 DOCK4

3.96e-0411512PS51650
DomainDOCK-C2

DOCK3 DOCK4

3.96e-0411512PF14429
DomainDHR-2

DOCK3 DOCK4

3.96e-0411512IPR027357
DomainDHR-2

DOCK3 DOCK4

3.96e-0411512PF06920
DomainDOCK

DOCK3 DOCK4

3.96e-0411512IPR026791
DomainWD40_repeat_dom

EML6 CDC20B GEMIN5 RIC1 MAPK8IP3

1.27e-03297515IPR017986
DomainApc4_WD40_dom

EML6 GEMIN5

1.35e-0320512IPR024977
DomainANAPC4_WD40

EML6 GEMIN5

1.35e-0320512PF12894
Domain-

EML6 CDC20B GEMIN5 RIC1 MAPK8IP3

2.10e-033335152.130.10.10
DomainWD40/YVTN_repeat-like_dom

EML6 CDC20B GEMIN5 RIC1 MAPK8IP3

2.15e-03335515IPR015943
DomainPeptidase_S1A

TPSAB1 HP TPSB2

3.64e-03113513IPR001314
DomainTRYPSIN_DOM

TPSAB1 HP TPSB2

3.82e-03115513PS50240
DomainTryp_SPc

TPSAB1 HP TPSB2

4.01e-03117513SM00020
DomainTrypsin

TPSAB1 HP TPSB2

4.40e-03121513PF00089
DomainTrypsin_dom

TPSAB1 HP TPSB2

4.40e-03121513IPR001254
DomainPeptidase_S1_PA

TPSAB1 HP TPSB2

4.61e-03123513IPR009003
DomainWD_REPEATS_1

EML6 CDC20B GEMIN5 RIC1

6.93e-03278514PS00678
DomainWD_REPEATS_2

EML6 CDC20B GEMIN5 RIC1

7.02e-03279514PS50082
DomainWD_REPEATS_REGION

EML6 CDC20B GEMIN5 RIC1

7.02e-03279514PS50294
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

DOCK3 TNRC18 CELSR3 CLCN7 KCNH2 NAGLU TRMT1 GEMIN5 RIC1 KIAA2013 MAPK8IP3

5.80e-071105521135748872
Pubmed

Human beta-tryptase is a ring-like tetramer with active sites facing a central pore.

TPSAB1 TPSB2

2.19e-0625229521329
Pubmed

The structure of the human betaII-tryptase tetramer: fo(u)r better or worse.

TPSAB1 TPSB2

2.19e-06252210500112
Pubmed

Human mast cell tryptase: multiple cDNAs and genes reveal a multigene serine protease family.

TPSAB1 TPSB2

2.19e-0625222187193
Pubmed

Characterization of a tryptase mRNA expressed in the human basophil cell line KU812.

TPSAB1 TPSB2

2.19e-0625228434231
Pubmed

Structural requirements and mechanism for heparin-dependent activation and tetramerization of human betaI- and betaII-tryptase.

TPSAB1 TPSB2

2.19e-06252215567416
Pubmed

Human tryptases alpha and beta/II are functionally distinct due, in part, to a single amino acid difference in one of the surface loops that forms the substrate-binding cleft.

TPSAB1 TPSB2

2.19e-06252210391906
Pubmed

The human mast cell tryptase tetramer: a fascinating riddle solved by structure.

TPSAB1 TPSB2

2.19e-06252210708850
Pubmed

Cloning and characterization of a second complementary DNA for human tryptase.

TPSAB1 TPSB2

2.19e-0625222203827
Pubmed

Tryptase haplotype in mastocytosis: relationship to disease variant and diagnostic utility of total tryptase levels.

TPSAB1 TPSB2

2.19e-06252217449330
Pubmed

Impact of naturally forming human α/β-tryptase heterotetramers in the pathogenesis of hereditary α-tryptasemia.

TPSAB1 TPSB2

2.19e-06252231337736
Pubmed

Characterization of two highly polymorphic human tryptase loci and comparison with a newly discovered monkey tryptase ortholog.

TPSAB1 TPSB2

2.19e-06252210898108
Pubmed

Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16.

TPSAB1 CLCN7 TPSB2 MAPK8IP3

4.73e-067452411157797
Pubmed

Characterization of genes encoding known and novel human mast cell tryptases on chromosome 16p13.3.

TPSAB1 TPSB2

6.57e-0635229920877
Pubmed

Combination of haptoglobin and osteopontin could predict colorectal cancer hepatic metastasis.

HP PTGIS

6.57e-06352222219064
Pubmed

Human subjects are protected from mast cell tryptase deficiency despite frequent inheritance of loss-of-function mutations.

TPSAB1 TPSB2

6.57e-06352219748655
Pubmed

Characterization of human gamma-tryptases, novel members of the chromosome 16p mast cell tryptase and prostasin gene families.

TPSAB1 TPSB2

2.19e-05552210843716
Pubmed

New developments in the genetics and activation of mast cell proteases.

TPSAB1 TPSB2

3.28e-05652212217407
Pubmed

The Arf family GTPase Arl4A complexes with ELMO proteins to promote actin cytoskeleton remodeling and reveals a versatile Ras-binding domain in the ELMO proteins family.

DOCK3 DOCK4

1.69e-041352221930703
Pubmed

Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity.

DOCK3 DOCK4

1.97e-041452212432077
Pubmed

Mitochondrial DNA Maintenance Defects Overview

TK2 RNASEH1

2.27e-041552229517884
Pubmed

Candidate gene analysis in an on-going genome-wide association study of attention-deficit hyperactivity disorder: suggestive association signals in ADRA1A.

DOCK3 NR4A2

8.08e-042852219352218
Pubmed

Biological, clinical and population relevance of 95 loci for blood lipids.

HP FER1L4 ANKRD55

1.38e-0314652320686565
Pubmed

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.

DOCK3 TPSAB1 CELSR3 TPSB2

1.49e-0332952417474147
CytobandEnsembl 112 genes in cytogenetic band chr16p13

TPSAB1 CLCN7 TPSB2 MAPK8IP3

1.39e-03426524chr16p13
Cytoband5q11.2

CDC20B ANKRD55

1.61e-03525225q11.2
GeneFamilyWD repeat domain containing

EML6 CDC20B GEMIN5

6.80e-03262273362
CoexpressionFOURATI_BLOOD_TWINRIX_AGE_25_83YO_RESPONDERS_VS_POOR_RESPONDERS_0DY_DN

FAH TPSAB1 TNRC18 HP TK2 TPSB2 KIAA2013 SLC27A3 CFAP46

1.44e-05746529M40863
CoexpressionAtlasgeo_heart_top-relative-expression-ranked_1000_k-means-cluster#3

TPSAB1 KCNH2 TPSB2

1.04e-0518513geo_heart_1000_K3
ToppCellMyeloid-D_(Mast_cell)|World / shred on cell class and cell subclass (v4)

TPSAB1 CD244 NR4A2 A4GNT TPSB2

4.34e-07130525574e262eb4ed2d69c3da68be061cebac9fefc29e
ToppCelldistal-Hematologic-Basophil/Mast_2-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TPSAB1 CELSR3 KCNH2 NR4A2 TPSB2

3.04e-06193525f22d0a2ea6bbdd625909ccb6a89aca89ab670306
ToppCelldistal-Hematologic-Basophil/Mast_2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TPSAB1 CELSR3 KCNH2 NR4A2 TPSB2

3.04e-06193525dcdc1498726c68bf590bf84cb81e5f7fb7ba4d78
ToppCelldistal-3-Hematologic-Basophil/Mast_2|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TPSAB1 CELSR3 KCNH2 NR4A2 TPSB2

3.04e-0619352523c6c798525dad43eff792727902ea562bf373be
ToppCellTCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Papillary_Muscle_Invasive_Urothelial_Carcinoma|TCGA-Bladder / Sample_Type by Project: Shred V9

MZF1 GGT6 FER1L4 AIG1

3.48e-05158524dc559503bab3ec1b9ea54ef2e896d1be33e5344c
ToppCellnormal_Pleural_Fluid-Myeloid_cells-Undetermined|Myeloid_cells / Location, Cell class and cell subclass

TPSAB1 PTGIS VPS29 TPSB2

3.93e-05163524be774c0ba38fa89a9c0076524cf05d593c6c6826
ToppCell10x5'-Liver-Lymphocytic_T_CD4-Tnaive/CM_CD4_activated|Liver / Manually curated celltypes from each tissue

DNHD1 KCNH2 FAM241B ANKRD55

4.21e-051665249afa33b5ad27dc33576be592f9b22d8161366838
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Parm1-Excitatory_Neuron.Slc17a7.Parm1.Nnat_(Deep_layer_pyramidal_cells--layer_5)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

A4GNT RFX6 TPSB2

4.30e-05585231d938d8ab4148a77f54322bd5501c4ca53665aef
ToppCellmild-Myeloid-Eosinophils|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

TPSAB1 KCNH2 ANKRD55 TPSB2

4.73e-051715245c8198182495bda7a826e9d80aa467f4eb1094ec
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Granulocytic-Mast_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TPSAB1 KCNH2 EML6 TPSB2

5.41e-0517752486c41d262142eeaa95ea7fa6668169eb1bb2953f
ToppCell3'-Broncho-tracheal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TPSAB1 KCNH2 NR4A2 TPSB2

5.65e-0517952440441de2d679733ecbf2145fabc3ed65a53310eb
ToppCelldroplet-Kidney-nan-18m-Epithelial-Stroma____kidney_mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR20 KCNH2 NR4A2 PTGIS

5.77e-05180524b6f44fdedc33b7d93b0074e8e9c8cc32009d4c4d
ToppCellCOPD-Myeloid-Mast|World / Disease state, Lineage and Cell class

TPSAB1 KCNH2 TPSB2 RIC1

6.03e-0518252468a1e7b804f309bfd6c23d65fad20a9a962712ae
ToppCellIIH-Treg-proli_CD4|IIH / Condition, Cell_class and T cell subcluster

TNRC18 UPB1 SRD5A1 FAM241B

6.03e-051825245c7d02da9ca2bca49db9832704b6894dfaa08a71
ToppCell3'-Adult-LargeIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CELSR3 EML6 RFX6 FAM241B

6.16e-0518352449f3ddc1c7c04b4ca837dbd6dad995add82941d6
ToppCellcontrol-Myeloid-Eosinophils|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

TPSAB1 CD244 KCNH2 TPSB2

6.29e-05184524fad517d047e8eaeaa5bd4f311d770880568dd13c
ToppCelldroplet-Bladder-BLADDER-1m-Epithelial-luminal_bladder_epithelial_cell_(umbrella_cell)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM184A SYT8 FER1L4 SRD5A1

6.29e-05184524382b1e90b3f437af596750669c0465a169d97095
ToppCellCOPD-Myeloid-Mast|COPD / Disease state, Lineage and Cell class

TPSAB1 KCNH2 TPSB2 RIC1

6.56e-05186524def6f0f284acc2154738574c8c5d3d2a5ef1f208
ToppCell5'-Parenchyma_lung-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TPSAB1 KCNH2 NR4A2 TPSB2

6.69e-05187524bdcef4f3e093c3646b639a189bbe93d6f4c40f3c
ToppCell5'-Parenchyma_lung-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TPSAB1 KCNH2 NR4A2 TPSB2

6.69e-0518752409348f1e8bbbca8dca885461937b9b1dd248b034
ToppCell5'-Parenchyma_lung-Immune_Myeloid_mast|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TPSAB1 KCNH2 NR4A2 TPSB2

6.69e-051875240f7a42c55997e34a0d20e492e16b03e91e965335
ToppCell5'-Parenchyma_lung-Immune_Myeloid_mast-Myeloid_Mast/Baso|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TPSAB1 KCNH2 NR4A2 TPSB2

6.69e-05187524064730fa72f8637c3db3fc34d2e363d2b9a38f1d
ToppCellfacs-Lung-EPCAM-24m-Epithelial-Club_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYT8 FER1L4 SRD5A1 FAM241B

6.69e-0518752474112df9b34051ae5cd2427ccfa3399eccff0076
ToppCellfacs-Lung-EPCAM-24m-Epithelial-club_cell_of_bronchiole|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYT8 FER1L4 SRD5A1 FAM241B

6.69e-05187524214ce9b55fd6ce2fe7bd4cf4b1383517f5f0d759
ToppCellfacs-Bladder|facs / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYT8 FER1L4 SRD5A1 PTGIS

6.69e-05187524dd5ca59417fd1b388fd975f0f3e1f3245d66ebc5
ToppCelldroplet-Kidney-nan-18m-Epithelial-kidney_mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

B3GALT1 GPR20 NR4A2 PTGIS

6.83e-05188524d1a4cd4db95d8d32b79156290f7867f32824cc87
ToppCell5'-Parenchyma_lung-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TPSAB1 KCNH2 NR4A2 TPSB2

6.98e-05189524f01158bb15df3117fae1271bf8cf8c2501422671
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Undetermined|Myeloid_cells / Location, Cell class and cell subclass

TPSAB1 HP KCNH2 TPSB2

6.98e-05189524b46adb47768a7b6d801c457d7ba65508edfc36a5
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Undetermined|metastatic_Lymph_Node / Location, Cell class and cell subclass

TPSAB1 KCNH2 VPS29 TPSB2

7.56e-0519352447249aabdd912052aa635d276eed20d32b525393
ToppCell3'-Parenchyma_lung-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TPSAB1 KCNH2 NR4A2 TPSB2

7.56e-05193524c17e87c042ef095ac99fdd6facf3bc2886924dc4
ToppCell3'-Broncho-tracheal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TPSAB1 KCNH2 NR4A2 TPSB2

7.72e-051945249d7f232ef5f27c28f325edfa6614f479013acbba
ToppCellproximal-Hematologic-Basophil/Mast_1-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

DOCK3 TPSAB1 KCNH2 TPSB2

8.03e-05196524d3ca25df013967b9d871c01a4785a76661b784ca
ToppCellproximal-3-Hematologic-Basophil/Mast_1|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

DOCK3 TPSAB1 KCNH2 TPSB2

8.03e-051965241a5d0d2fee932f97614bf923686fdc2655c7ca75
ToppCellproximal-Hematologic-Basophil/Mast_1|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

DOCK3 TPSAB1 KCNH2 TPSB2

8.03e-051965249dddf3f33d8f507313f24dfb34d68bcafa064e94
ToppCellLung_Parenchyma-Control-Myeloid-Mast_cell|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

TPSAB1 KCNH2 NR4A2 TPSB2

8.35e-051985240af55f2b859e4626e23e2733bf9ae2ace4547079
ToppCellLung_Parenchyma-Control-Myeloid-Mast_cell-Mast_cells-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TPSAB1 KCNH2 NR4A2 TPSB2

8.35e-05198524f75800b4f3cf0d493226db8db7c949caade0ff90
ToppCellParenchyma_Control_(B.)-Immune-TX-Mast_cells|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

TPSAB1 KCNH2 NR4A2 TPSB2

8.35e-0519852445089e0adf2c00f4b0bccd701f4daebf25858006
ToppCellLung_Parenchyma-Control-Myeloid-Mast_cell-Mast_cells|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

TPSAB1 KCNH2 NR4A2 TPSB2

8.35e-051985244163220f4ccb825a8399298cfac8411eb2acc9a2
ToppCellCaecum-T_cell-CD8_T|T_cell / Region, Cell class and subclass

TPSAB1 CD244 NR4A2 TPSB2

8.68e-0520052440e435f5dd1a0f6554f87dc1e170a740fd733d5b
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid-Mast_cell|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

TPSAB1 KCNH2 NR4A2 TPSB2

8.68e-0520052421de2cf284c8d2aa464f3d403f0e292e1f654e0a
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid-Mast_cell-Mast_cell|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

TPSAB1 KCNH2 NR4A2 TPSB2

8.68e-05200524a338b2b94901e4614ef78e82f580b67891f7c849
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Parm1|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

TPSAB1 A4GNT TPSB2

2.96e-041115231847dde68d349114286bc3317be6339666df4aa2
ToppCellParenchymal-10x5prime-Immune_Myeloid-Myeloid|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TPSAB1 KCNH2 TPSB2

3.45e-04117523f0c738b6b850733f9af68704172554177a1c1198
ToppCellParenchymal-10x5prime-Immune_Myeloid-Myeloid-Megakaryocyte|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TPSAB1 KCNH2 TPSB2

3.45e-04117523b5cb9d69ddd42331134f7e4bd51bd1c31030893c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic-Mast_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TPSAB1 NR4A2 TPSB2

3.90e-04122523032b5da8befcb1a159245f8d0c67f91795883ee0
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Hpse_Sema3c|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SYTL5 VRTN RFX6

3.90e-04122523eae9d94f8510ac0f434942451d55c7260977b178
ToppCell(08)_PNEC-(2)_48hpi|(08)_PNEC / shred by cell type and Timepoint

SYTL5 A4GNT RIC1

6.07e-04142523e95d34170f5053678e0dd9793e68d93c03b05822
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma|TCGA-Pancreas / Sample_Type by Project: Shred V9

TPSAB1 TPSB2

6.36e-0432522b2d87153b4aefefd7b5e31ea67aa43e5f599e734
ToppCellTCGA-Pancreas-Primary_Tumor|TCGA-Pancreas / Sample_Type by Project: Shred V9

TPSAB1 TPSB2

6.36e-0432522f5bcaacbddfb85439ebf5908762bf39cb72b727c
ToppCellfacs-Trachea-3m-Hematologic-myeloid-granulocyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TPSAB1 HP TPSB2

6.45e-04145523e381fd90fdaf2ff8c0d2584b6e0a4506418c9593
ToppCellSevere-Myeloid-Mast-|Severe / Condition, Lineage, Cell class and cell subclass

TPSAB1 KCNH2 TPSB2

6.45e-04145523ce307d45425a5191882078f049f85477eec40b69
ToppCellSevere-Myeloid-Mast|Severe / Condition, Lineage, Cell class and cell subclass

TPSAB1 KCNH2 TPSB2

6.45e-04145523e0bfd2ffdbd6c197ef0a04e983396ebd87ef7127
ToppCell356C-Myeloid-Mast_cell|356C / Donor, Lineage, Cell class and subclass (all cells)

TPSAB1 KCNH2 TPSB2

6.85e-041485231668d8a9e680da335362744f36b05446c499347e
ToppCell356C-Myeloid-Mast_cell-|356C / Donor, Lineage, Cell class and subclass (all cells)

TPSAB1 KCNH2 TPSB2

6.85e-0414852318511ba10765eda937c5a710626361f7e6b9b321
ToppCellE18.5-samps-Epithelial-Epithelial-non_alveolar-Club_cell|E18.5-samps / Age Group, Lineage, Cell class and subclass

TMEM184A HP FAM241B

6.98e-0414952382edfecb7981d8c336cf9da7aa7e2b3f7a017a3f
ToppCellE18.5-samps-Epithelial-Epithelial-non_alveolar|E18.5-samps / Age Group, Lineage, Cell class and subclass

TMEM184A HP FAM241B

6.98e-0414952314a01ae540db8a350ea26a350b2e6ce6c07639d9
ToppCellfacs-Trachea-nan-3m-Myeloid-granulocyte|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TPSAB1 HP TPSB2

6.98e-041495239c4837aa63e46382ff45a41c72beb5722b3ada19
ToppCellPND10-Immune-Immune_Myeloid-Granulocytic|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TPSAB1 CD244 TPSB2

6.98e-04149523c9334f319a0c943268e54b6f0c9446736172c3a9
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic-Mast_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TPSAB1 KCNH2 TPSB2

7.26e-04151523f5ae450e3daa10540ca8437d05efe2d86ac70960
ToppCellChildren_(3_yrs)-Immune-mast_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

TPSAB1 KCNH2 TPSB2

7.26e-04151523bbf735c6433c3fc2feedb24ed6f48c51d545fb60
ToppCellfacs-Trachea-nan-24m-Myeloid-granulocyte|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TPSAB1 HP TPSB2

7.26e-0415152326fd55efb647c41436416d45952ee97b050e632c
ToppCell368C-Myeloid-Mast_cell|368C / Donor, Lineage, Cell class and subclass (all cells)

TPSAB1 KCNH2 TPSB2

7.40e-04152523faf30245a1690aaa27c7be0832797c340e4af4d7
ToppCellTracheal-10x3prime_v2-Immune_Myeloid-Mast_cell-Mast_cell|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

TPSAB1 KCNH2 TPSB2

7.40e-04152523321d322d58c12fd752de4e8ea873f3f367302813
ToppCell368C-Myeloid-Mast_cell-|368C / Donor, Lineage, Cell class and subclass (all cells)

TPSAB1 KCNH2 TPSB2

7.40e-04152523519c9ed05fdaf420e42147ffae1dc05a7f86fdd4
ToppCellTracheal-10x3prime_v2-Immune_Myeloid-Mast_cell|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

TPSAB1 KCNH2 TPSB2

7.40e-04152523a4d50e9af02231c5573aee905cf0905391e6da34
ToppCell3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SYT8 GGT6 PSORS1C1

7.54e-0415352392a5307b8e4dcf9ee42134b4c0645f9d488df61a
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(NPW+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CELSR3 SYTL5 RFX6

7.83e-04155523498e52e2364ff44d3c0c707ba22468217031f5bd
ToppCellCOVID-19-Mast_cells|COVID-19 / group, cell type (main and fine annotations)

TPSAB1 KCNH2 TPSB2

7.98e-04156523159504d43421ee83b9ab484816333ae549c9c2fd
ToppCellCOVID-19-Mast_cells-Mast_cells|COVID-19 / group, cell type (main and fine annotations)

TPSAB1 KCNH2 TPSB2

7.98e-04156523bc10b94673184ef384c6665b16a1209a8975a4f1
ToppCellfacs-Trachea-24m-Hematologic-myeloid-granulocyte|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TPSAB1 HP TPSB2

8.13e-04157523188d2f85babcd4eefe20e7a392d851b2e1185bab
ToppCelldroplet-Heart-nan-18m-Myeloid-mast_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELSR3 CD244 HP

8.28e-041585237ebc8b778c97c0faa79e2d80c98b887fa635f901
ToppCellCOVID_non-vent-Myeloid-Monocytic-SC_&_Eosinophil|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

TPSAB1 SYTL5 KCNH2

8.28e-041585230d4fe87fc7901dd5f9c004e91708a03cafdb4ad9
ToppCelldroplet-Liver-LIVER_NPC-30m-Myeloid-myeloid_leukocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD244 NR4A2 SLC27A3

8.28e-0415852390ca742739a208d457db087655ba3d1c18a9da57
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell-D231|Adult / Lineage, Cell type, age group and donor

UPB1 GPR20 KCNH2

8.28e-041585238d64c0c9de910a3f4658778642d183c8b9b6f6a2
ToppCelldroplet-Heart-nan-18m-Myeloid|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELSR3 CD244 HP

8.28e-0415852381a5a73090804d41429d297ba2462a842f39d380
ToppCelldroplet-Heart-nan-18m-Myeloid-cardiac_mast_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELSR3 CD244 HP

8.28e-041585239596b7b0f6f5157a43d67d2e67fb75a2624a6bb9
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DOCK3 EML6 RFX6

8.43e-041595237747cef94c55144fddcd024a7495318357f1351b
ToppCellPND10-Immune-Immune_Myeloid-Granulocytic-Mast|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TPSAB1 NAGA TPSB2

8.58e-041605236393e3d5c5c8176c93aecd89b313bd054a00d474
ToppCell343B-Myeloid-Mast_cell-|343B / Donor, Lineage, Cell class and subclass (all cells)

TPSAB1 KCNH2 TPSB2

8.58e-04160523a2f09b5955602819c8978f4372130c8ef915cd07
ToppCellPND10-Immune-Immune_Myeloid-Granulocytic-Mast-Mast_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TPSAB1 NAGA TPSB2

8.58e-041605232065938e944eb99478fd8132c2c03adeaee6d447
ToppCell343B-Myeloid-Mast_cell|343B / Donor, Lineage, Cell class and subclass (all cells)

TPSAB1 KCNH2 TPSB2

8.58e-04160523133ecae0a894d9a0d49d58859623359096b6f030
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-plasmacytoid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UPB1 QTRT1 ANKRD55

8.74e-04161523ed93cb6c133855a5c244821e1a260aae8ab4df9a
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Plasmacytoid_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UPB1 QTRT1 ANKRD55

8.74e-041615230089d7bb305c592392791862a3341fc92af8f3e2
ToppCellVE-mono3|VE / Condition, Cell_class and T cell subcluster

DOCK4 HP NR4A2

8.74e-041615237df3fefc55ab43b897fc78d1f0c7383b10ac33d5
ToppCelldroplet-Thymus-nan-21m-Myeloid-Macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK4 UPB1 CD244

8.74e-04161523441ebd3c029861d833fbcf8a68fc740d9de8ef2f
ToppCellVE-mono3-|VE / Condition, Cell_class and T cell subcluster

DOCK4 HP NR4A2

8.74e-041615234e45bf7eceb0ee30dec4d8852778366776ea5a8f
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Myeloid-Monocytic-Classical_Monocyte-Mono_c1-CD14-CCL3|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TK2 NAGA NR4A2

8.90e-0416252388576622af741cf5f754e328bd6d53385ef53be6
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAH UPB1 HP

9.06e-041635230b4d234bdd57d5e991f68942333ca89f70ea28df
ToppCellfacs-Marrow-KLS-24m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK3 B3GALT1 ANKRD55

9.06e-04163523b83a35c4426d66b5734a98fa6c72b345fe462030
ToppCellFetal_29-31_weeks-Immune-mast_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TPSAB1 ANKRD55 TPSB2

9.06e-0416352303b2ec226adffba3ce893f3d12e549c841e662fd
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Epithelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAH UPB1 HP

9.06e-0416352361b4e38d7bbbb031100670928e6fd4f7ea23814f
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAH UPB1 HP

9.06e-04163523cc728796e52d0e6cc1198e0732370c62380e951d
ToppCellfacs-Marrow-KLS-24m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK3 B3GALT1 ANKRD55

9.06e-04163523c20ca9b6b4170ebcb0e66eef3e5d8ebff22b1a91
ToppCellBasal_cells-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

SYT8 SYTL5 EML6

9.22e-04164523b15a26130a1ea1b370b6e3be21f02a0d6aaf6b3c
ToppCellfacs-Marrow-KLS-24m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK3 B3GALT1 ANKRD55

9.22e-04164523d2b5f51af7fcffddebe997ee302bacbd85d76852
ToppCell356C-Myeloid-Mast_cell|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

TPSAB1 KCNH2 TPSB2

9.22e-04164523b3192c443f4848e6a8afdb89c155f9ec42a154b0
ToppCellPND10-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HP SYTL5 CDC20B

9.22e-041645236ea188e17895961cd112152fb111d08641cc5e45
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

DOCK3 KCNH2 RFX6

9.22e-04164523be49af6335f2505065cde2cb9800e4a5516811b1
ToppCell356C-Myeloid-Mast_cell-|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

TPSAB1 KCNH2 TPSB2

9.22e-04164523f7288ec4daf494dae770ea6c58bead27660ccae1
ToppCellMild-Myeloid-Mast-|Mild / Condition, Lineage, Cell class and cell subclass

TPSAB1 KCNH2 TPSB2

9.38e-0416552393d3909a0f5f43d473d5005c842d7d73e25eceed
Drugpimaradiene

TPSAB1 HP TPSB2

1.83e-0611523CID000440909
DrugFdTTP

TPSAB1 TK2 TPSB2

5.01e-0615523CID000162005
DrugProcaine hydrochloride [51-05-8]; Down 200; 14.6uM; HL60; HT_HG-U133A

DOCK4 TUT4 SRD5A1 NR4A2 QTRT1 MAPK8IP3

5.85e-061985261838_DN
DrugCorynanthine hydrochloride [66634-44-4]; Down 200; 10.2uM; MCF7; HT_HG-U133A

TUT4 MZF1 KCNH2 AIG1 NR4A2 MAPK8IP3

5.85e-061985262786_DN
Drug5 alpha-androstan-3-one

TPSAB1 SRD5A1 TPSB2

6.16e-0616523CID000102028
Drugthymidine glycol monophosphate

TPSAB1 TPSB2

1.53e-053522CID000165415
DrugBrunfelsamidine

TPSAB1 TPSB2

3.06e-054522CID005281683
Drug2-methylundecanal

TPSAB1 HP TPSB2

3.16e-0527523CID000061031
Drug1,1/t,t

FAH TPSAB1 TPSB2

4.83e-0531523CID000444372
Druggenistein; Up 200; 10uM; HL60; HT_HG-U133A

DOCK4 TUT4 SRD5A1 NR4A2 MAPK8IP3

5.47e-051795251176_UP
DrugTrichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A

DOCK4 TUT4 KCNH2 AIG1 MAPK8IP3

7.63e-051925252450_UP
Drugcarbathymidine

TK2 RNASEH1

7.63e-056522CID000130766
DrugAttpsa

TPSAB1 TPSB2

7.63e-056522CID005487511
Drugh bu

FAH HP

7.63e-056522CID000446167
DrugIoxaglic acid [59017-64-0]; Down 200; 3.2uM; HL60; HT_HG-U133A

DOCK4 SRD5A1 NR4A2 HMBS MAPK8IP3

8.21e-051955252966_DN
DrugSolasodine [126-17-0]; Down 200; 9.6uM; MCF7; HT_HG-U133A

TUT4 CLCN7 KCNH2 PTGIS MAPK8IP3

8.41e-051965253830_DN
DrugRauwolscine hydrochloride [6211-32-1]; Up 200; 10.2uM; MCF7; HT_HG-U133A

DOCK4 TK2 AIG1 QTRT1 MAPK8IP3

8.41e-051965252778_UP
Drug3-alpha-Hydroxy-5-beta-androstan-17-one [53-42-9]; Up 200; 13.8uM; MCF7; HT_HG-U133A

CLCN7 TK2 KCNH2 A4GNT MAPK8IP3

8.61e-051975254764_UP
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

TK2 NAGLU AIG1 QTRT1 MAPK8IP3

8.61e-051975253566_DN
DrugLobelanidine hydrochloride [6112-86-3]; Down 200; 10.6uM; MCF7; HT_HG-U133A

CLCN7 TK2 NAGLU AIG1 NR4A2

8.61e-051975255500_DN
DrugBenzamil hydrochloride [2898-76-2]; Up 200; 11.2uM; MCF7; HT_HG-U133A

UPB1 TUT4 CLCN7 TK2 A4GNT

8.82e-051985256056_UP
Drug(-)-Quinpirole hydrochloride [85760-74-3]; Up 200; 15.6uM; MCF7; HT_HG-U133A

CELSR3 MZF1 TK2 AIG1 QTRT1

8.82e-051985257481_UP
DrugDanazol [17230-88-5]; Up 200; 11.8uM; MCF7; HT_HG-U133A

DOCK4 CLCN7 TK2 KCNH2 NR4A2

8.82e-051985251538_UP
Drugioxaglate

TPSAB1 TPSB2

1.07e-047522CID000003742
DrugTelebrix

TPSAB1 TPSB2

1.07e-047522CID000034536
Diseasetryptase beta-2 measurement

TPSAB1 CLCN7 TPSB2

3.82e-079503EFO_0008306
Diseasethioredoxin domain-containing protein 12 measurement

DOCK3 TUT4 CELSR3

4.01e-0539503EFO_0008298
Diseaseurticaria

TPSAB1 TPSB2

5.24e-0420502EFO_0005531

Protein segments in the cluster

PeptideGeneStartEntry
LVNMGFPQWHLGNHA

FAM241B

71

Q96D05
LDNFIPGWLNHGMHT

AIG1

121

Q9NVV5
HGTFPGLWLALMAVH

GPR20

46

Q99678
GFLPHHPFLWECMEN

A4GNT

196

Q9UNA3
GIHPFQNSGFNHWKM

B3GALT1

276

Q9Y5Z6
LMEFGQWLHHRHFPL

CFAP46

1221

Q8IYW2
NHQDNEGMTPLHWAA

ANKRD55

156

Q3KP44
HSMPVFWNQSLELGH

DNHD1

4226

Q96M86
PFIWCMLHNFGGNHG

NAGLU

401

P54802
EIQHFLLHFWQGMPD

RFX6

286

Q8HWS3
DGLLHLIHWEGMTNG

RIC1

161

Q4ADV7
GSFPWQAKMVSHHNL

HP

171

P00738
QWDLSNYHLMDLGHP

MAPK8IP3

1031

Q9UPT6
HSPGLLQGSLHMWID

FER1L4

1456

A9Z1Z3
QPHMDSRIGWLHNLG

KCNH2

576

Q12809
HGNMWDLSSPGLINF

CLCN7

346

P51798
QLTGFPGMEKAHHWI

OR51B6

11

Q9H340
WRNVRGHNPLGLMYH

TK2

86

O00142
WQNLGEHKIHFIPGM

DOCK3

1081

Q8IZD9
MWQNLGEHKLHFIPA

DOCK4

1051

Q8N1I0
RHHPLNWLMYSINGA

UPB1

236

Q9UBR1
PHATGLGAMFWGLFH

GGT6

141

Q6P531
MLGHLSVVGALSWNH

CDC20B

311

Q86Y33
HMEGEVWGLAAHPLL

EML6

996

Q6ZMW3
NALMPNWLHLPVGYH

FAH

146

P16930
MGWHNRVGQILHPEE

HMBS

196

P08397
MAHPHHFRGNGTLSW

CELSR3

1761

Q9NYQ7
NGFHHILKWENGSLP

CD244

61

Q9BZW8
PMWDDPGSLHNFHQN

NR4A2

141

P43354
ASGQPLQHWADMLAH

SYT8

351

Q8NBV8
NPQWNHTFMFSGIHP

SYTL5

636

Q8TDW5
HCGQRHQLGGPMWAE

TRMT1

386

Q9NXH9
MHFCGGSLIHPQWVL

TPSAB1

56

Q15661
MHFCGGSLIHPQWVL

TPSB2

56

P20231
IQKANGLHGFMNWPH

QTRT1

86

Q9BXR0
GLHGFMNWPHNLLTD

QTRT1

91

Q9BXR0
MNWPHNLLTDSGGFQ

QTRT1

96

Q9BXR0
RLKNYNMPWGAGHNH

PTGIS

426

Q16647
NMPWGAGHNHCLGRS

PTGIS

431

Q16647
DHMGNSSQGAPWLFL

TMEM184A

36

Q6ZMB5
LMHLAPGFKLDHAWA

C11orf68

171

Q9H3H3
IQWMHVPGHSGFIGN

RNASEH1

256

O60930
NLPMVQLWAAHAHEG

TNRC18

101

O15417
RAMGLHLWAAGPGTH

SLC27A3

236

Q5K4L6
DGNWIYGGHNHPPLM

YY2

46

O15391
NGHPELFHQLMLWKG

GEMIN5

916

Q8TEQ6
PANHFWHAGDLQAMI

PSORS1C1

51

Q9UIG5
HGHQVIPWGDMASLA

VPS29

86

Q9UBQ0
GLWLTGMLINIHSDH

SRD5A1

156

P18405
MWAGQPLTSHFFRHQ

VRTN

221

Q9H8Y1
SWPYGLHQNFMHQGN

TUT4

1596

Q5TAX3
NLTGGNHLFLLDMHW

TTF2

1076

Q9UNY4
NHLFLLDMHWNPSLE

TTF2

1081

Q9UNY4
FSGHATMHAENLWPG

KIAA2013

401

Q8IYS2
GHWNDPDMLLIGNFG

NAGA

246

P17050
HLHVPWDLGMAGLSG

MZF1

276

P28698