Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	arylsulfatase activity	SULF2 SULF1 ARSG	3.11e-05	14	90	3	GO:0004065
GeneOntologyMolecularFunction	sulfuric ester hydrolase activity	SULF2 SULF1 ARSG	5.75e-05	17	90	3	GO:0008484
GeneOntologyMolecularFunction	N-acetylglucosamine-6-sulfatase activity	SULF2 SULF1	6.01e-05	3	90	2	GO:0008449
GeneOntologyMolecularFunction	folic acid receptor activity	FOLR1 FOLR2	6.01e-05	3	90	2	GO:0061714
GeneOntologyMolecularFunction	serine-type endopeptidase inhibitor activity	SLCO1B7 SPINT2 TFPI2 SLCO1B3 TFPI	1.13e-04	105	90	5	GO:0004867
GeneOntologyMolecularFunction	peptidase regulator activity	SLCO1B7 SPINT2 FN1 TFPI2 CST5 SLCO1B3 TFPI	1.62e-04	257	90	7	GO:0061134
GeneOntologyMolecularFunction	endopeptidase inhibitor activity	SLCO1B7 SPINT2 TFPI2 CST5 SLCO1B3 TFPI	1.64e-04	180	90	6	GO:0004866
GeneOntologyMolecularFunction	peptidase inhibitor activity	SLCO1B7 SPINT2 TFPI2 CST5 SLCO1B3 TFPI	2.02e-04	187	90	6	GO:0030414
GeneOntologyMolecularFunction	endopeptidase regulator activity	SLCO1B7 SPINT2 TFPI2 CST5 SLCO1B3 TFPI	2.98e-04	201	90	6	GO:0061135
GeneOntologyMolecularFunction	amide binding	CACNA1B IGF1R NFATC1 FOLR1 FOLR2 PPIL1 CST5	4.07e-04	299	90	7	GO:0033218
GeneOntologyMolecularFunction	catalytic activity, acting on RNA	NSUN5 EXOSC9 TUT4 DDX50 PUS10 DHX57 CARS2 YARS2	5.89e-04	417	90	8	GO:0140098
GeneOntologyMolecularFunction	hemoglobin binding	HPR LRP2	1.08e-03	11	90	2	GO:0030492
GeneOntologyMolecularFunction	glycosaminoglycan binding	SULF2 FN1 SULF1 PLA2G5 SEMA5A ADAMTS5	1.34e-03	268	90	6	GO:0005539
GeneOntologyMolecularFunction	insulin-like growth factor I binding	IGF1R LRP2	1.52e-03	13	90	2	GO:0031994
GeneOntologyMolecularFunction	prostaglandin transmembrane transporter activity	SLCO1B7 SLCO1B3	1.76e-03	14	90	2	GO:0015132
GeneOntologyMolecularFunction	icosanoid transmembrane transporter activity	SLCO1B7 SLCO1B3	2.03e-03	15	90	2	GO:0071714
GeneOntologyMolecularFunction	oligopeptide transmembrane transporter activity	SLCO1B7 SLCO1B3	2.31e-03	16	90	2	GO:0035673
GeneOntologyBiologicalProcess	extracellular matrix organization	NTN4 SULF2 SPINT2 FN1 ADAMTS6 SULF1 CST5 ETS1 ADAMTS20 SEMA5A ADAMTS5 NPNT	4.63e-08	377	85	12	GO:0030198
GeneOntologyBiologicalProcess	extracellular structure organization	NTN4 SULF2 SPINT2 FN1 ADAMTS6 SULF1 CST5 ETS1 ADAMTS20 SEMA5A ADAMTS5 NPNT	4.77e-08	378	85	12	GO:0043062
GeneOntologyBiologicalProcess	external encapsulating structure organization	NTN4 SULF2 SPINT2 FN1 ADAMTS6 SULF1 CST5 ETS1 ADAMTS20 SEMA5A ADAMTS5 NPNT	4.90e-08	379	85	12	GO:0045229
GeneOntologyBiologicalProcess	folic acid transport	FOLR1 FOLR2 LRP2	1.09e-05	11	85	3	GO:0015884
GeneOntologyBiologicalProcess	cellular response to folic acid	FOLR1 FOLR2	1.68e-05	2	85	2	GO:0071231
GeneOntologyBiologicalProcess	esophagus smooth muscle contraction	SULF2 SULF1	1.68e-05	2	85	2	GO:0014846
GeneOntologyBiologicalProcess	gastro-intestinal system smooth muscle contraction	SULF2 HTR2B SULF1	2.97e-05	15	85	3	GO:0014831
GeneOntologyBiologicalProcess	morphogenesis of an epithelium	RAB23 NTN4 IGF1R SPINT2 NFATC1 FOLR1 SULF1 LRP2 SEMA5A CTSZ NPNT	4.64e-05	619	85	11	GO:0002009
GeneOntologyBiologicalProcess	morphogenesis of a branching epithelium	NTN4 SPINT2 NFATC1 SULF1 SEMA5A CTSZ NPNT	5.43e-05	236	85	7	GO:0061138
GeneOntologyBiologicalProcess	tissue morphogenesis	RAB23 NTN4 IGF1R SPINT2 NFATC1 FOLR1 SULF1 LRP2 SEMA5A ADAMTS5 CTSZ NPNT	5.64e-05	750	85	12	GO:0048729
GeneOntologyBiologicalProcess	morphogenesis of a branching structure	NTN4 SPINT2 NFATC1 SULF1 SEMA5A CTSZ NPNT	9.50e-05	258	85	7	GO:0001763
GeneOntologyBiologicalProcess	neural crest cell migration	HTR2B FN1 FOLR1 SEMA5A	1.25e-04	62	85	4	GO:0001755
GeneOntologyBiologicalProcess	mesenchymal cell migration	HTR2B FN1 FOLR1 SEMA5A	1.41e-04	64	85	4	GO:0090497
GeneOntologyBiologicalProcess	regulation of extracellular matrix disassembly	CST5 ETS1 SEMA5A	1.45e-04	25	85	3	GO:0010715
GeneOntologyBiologicalProcess	animal organ morphogenesis	RAB23 NTN4 SULF2 IGF1R HTR2B NFATC1 MYO6 FOLR1 SULF1 CST5 LRP2 TRPM1 ADAMTS5 CTSZ NPNT	1.93e-04	1269	85	15	GO:0009887
GeneOntologyBiologicalProcess	extracellular matrix disassembly	CST5 ETS1 SEMA5A ADAMTS5	2.61e-04	75	85	4	GO:0022617
GeneOntologyBiologicalProcess	epithelial tube morphogenesis	RAB23 SPINT2 NFATC1 FOLR1 LRP2 SEMA5A CTSZ NPNT	3.44e-04	421	85	8	GO:0060562
GeneOntologyBiologicalProcess	negative regulation of proteolysis	RAB23 USP5 SPINT2 TFPI2 CST5 CTSZ TFPI	3.97e-04	326	85	7	GO:0045861
GeneOntologyCellularComponent	extracellular matrix	NTN4 FN1 ADAMTS6 TFPI2 SULF1 CST5 ADAMTS20 ADAMTS5 CTSZ SVEP1 NPNT	1.17e-04	656	90	11	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	NTN4 FN1 ADAMTS6 TFPI2 SULF1 CST5 ADAMTS20 ADAMTS5 CTSZ SVEP1 NPNT	1.20e-04	658	90	11	GO:0030312
Domain	HELP	EML5 EML4 EML6	2.00e-06	6	88	3	PF03451
Domain	HELP	EML5 EML4 EML6	2.00e-06	6	88	3	IPR005108
Domain	Extracellular_sulfatase	SULF2 SULF1	2.19e-05	2	88	2	IPR014615
Domain	Extracellular_sulfatase_C	SULF2 SULF1	2.19e-05	2	88	2	IPR024609
Domain	DUF3740	SULF2 SULF1	2.19e-05	2	88	2	PF12548
Domain	Sulfatase_CS	SULF2 SULF1 ARSG	5.41e-05	16	88	3	IPR024607
Domain	SULFATASE_1	SULF2 SULF1 ARSG	6.55e-05	17	88	3	PS00523
Domain	SULFATASE_2	SULF2 SULF1 ARSG	6.55e-05	17	88	3	PS00149
Domain	Sulfatase	SULF2 SULF1 ARSG	7.84e-05	18	88	3	PF00884
Domain	Sulfatase_N	SULF2 SULF1 ARSG	7.84e-05	18	88	3	IPR000917
Domain	-	SPINT2 TFPI2 TFPI	7.84e-05	18	88	3	4.10.410.10
Domain	Prtase_inh_Kunz-CS	SPINT2 TFPI2 TFPI	7.84e-05	18	88	3	IPR020901
Domain	KU	SPINT2 TFPI2 TFPI	7.84e-05	18	88	3	SM00131
Domain	BPTI_KUNITZ_2	SPINT2 TFPI2 TFPI	9.27e-05	19	88	3	PS50279
Domain	Kunitz_BPTI	SPINT2 TFPI2 TFPI	9.27e-05	19	88	3	PF00014
Domain	BPTI_KUNITZ_1	SPINT2 TFPI2 TFPI	9.27e-05	19	88	3	PS00280
Domain	ADAM_spacer1	ADAMTS6 ADAMTS20 ADAMTS5	1.67e-04	23	88	3	IPR010294
Domain	ADAM_spacer1	ADAMTS6 ADAMTS20 ADAMTS5	1.67e-04	23	88	3	PF05986
Domain	Kunitz_BPTI	SPINT2 TFPI2 TFPI	1.67e-04	23	88	3	IPR002223
Domain	Peptidase_M12B_ADAM-TS	ADAMTS6 ADAMTS20 ADAMTS5	1.90e-04	24	88	3	IPR013273
Domain	Folate_rcpt	FOLR1 FOLR2	2.17e-04	5	88	2	IPR004269
Domain	TSP_1	ADAMTS6 ADAMTS20 SEMA5A ADAMTS5	2.22e-04	63	88	4	PF00090
Domain	TSP1	ADAMTS6 ADAMTS20 SEMA5A ADAMTS5	2.50e-04	65	88	4	SM00209
Domain	TSP1_rpt	ADAMTS6 ADAMTS20 SEMA5A ADAMTS5	2.50e-04	65	88	4	IPR000884
Domain	TSP1	ADAMTS6 ADAMTS20 SEMA5A ADAMTS5	2.50e-04	65	88	4	PS50092
Domain	Alkaline_phosphatase_core	SULF2 SULF1 ARSG	4.13e-04	31	88	3	IPR017850
Domain	Alkaline_Pase-like_a/b/a	SULF2 SULF1 ARSG	4.13e-04	31	88	3	IPR017849
Domain	-	SULF2 SULF1 ARSG	4.13e-04	31	88	3	3.40.720.10
Domain	Folate_rcpt-like	FOLR1 FOLR2	6.03e-04	8	88	2	IPR018143
Domain	Folate_rec	FOLR1 FOLR2	6.03e-04	8	88	2	PF03024
Domain	Peptidase_M12B_N	ADAMTS6 ADAMTS20 ADAMTS5	8.17e-04	39	88	3	IPR002870
Domain	Pep_M12B_propep	ADAMTS6 ADAMTS20 ADAMTS5	8.17e-04	39	88	3	PF01562
Domain	Growth_fac_rcpt_	NTN4 IGF1R LRP2 SVEP1 NPNT	8.55e-04	156	88	5	IPR009030
Domain	DISINTEGRIN_1	ADAMTS6 ADAMTS20 ADAMTS5	8.80e-04	40	88	3	PS00427
Domain	Reprolysin	ADAMTS6 ADAMTS20 ADAMTS5	8.80e-04	40	88	3	PF01421
Domain	ADAM_MEPRO	ADAMTS6 ADAMTS20 ADAMTS5	8.80e-04	40	88	3	PS50215
Domain	DISINTEGRIN_2	ADAMTS6 ADAMTS20 ADAMTS5	8.80e-04	40	88	3	PS50214
Domain	Peptidase_M12B	ADAMTS6 ADAMTS20 ADAMTS5	8.80e-04	40	88	3	IPR001590
Domain	Disintegrin_dom	ADAMTS6 ADAMTS20 ADAMTS5	9.47e-04	41	88	3	IPR001762
Domain	OA_transporter	SLCO1B7 SLCO1B3	1.40e-03	12	88	2	IPR004156
Domain	OATP	SLCO1B7 SLCO1B3	1.40e-03	12	88	2	PF03137
Domain	Quinoprotein_ADH-like_supfam	EML5 EML4 EML6	2.00e-03	53	88	3	IPR011047
Domain	SUSHI	HPR CSMD3 SVEP1	2.34e-03	56	88	3	PS50923
Domain	Sushi_SCR_CCP_dom	HPR CSMD3 SVEP1	2.46e-03	57	88	3	IPR000436
Domain	MAM_1	MDGA1 NPNT	2.52e-03	16	88	2	PS00740
Domain	MAM	MDGA1 NPNT	2.85e-03	17	88	2	SM00137
Domain	MAM	MDGA1 NPNT	3.20e-03	18	88	2	PF00629
Domain	MAM_dom	MDGA1 NPNT	3.20e-03	18	88	2	IPR000998
Domain	MAM_2	MDGA1 NPNT	3.20e-03	18	88	2	PS50060
Domain	AA_TRNA_LIGASE_I	CARS2 YARS2	3.56e-03	19	88	2	PS00178
Domain	Apc4_WD40_dom	EML5 EML6	3.95e-03	20	88	2	IPR024977
Domain	ANAPC4_WD40	EML5 EML6	3.95e-03	20	88	2	PF12894
Domain	TUDOR	SMN1 ALG13	5.21e-03	23	88	2	PS50304
Domain	MetalloPept_cat_dom	ADAMTS6 ADAMTS20 ADAMTS5	6.62e-03	81	88	3	IPR024079
Domain	-	ADAMTS6 ADAMTS20 ADAMTS5	6.62e-03	81	88	3	3.40.390.10
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	ADAMTS6 ADAMTS20 SEMA5A ADAMTS5	2.82e-05	39	64	4	M27417
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	ADAMTS6 ADAMTS20 SEMA5A ADAMTS5	2.82e-05	39	64	4	MM15165
Pathway	REACTOME_DISEASES_OF_GLYCOSYLATION	ADAMTS6 ADAMTS20 B3GALT6 SEMA5A ADAMTS5 ALG13	4.53e-05	143	64	6	M27275
Pathway	REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS	ADAMTS6 ADAMTS20 SEMA5A ADAMTS5	2.53e-04	68	64	4	M27303
Pubmed	Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.	FN1 HPR CST5 ADAMTS5 SVEP1 TFPI NPNT	3.89e-06	248	90	7	24006456
Pubmed	Expression patterns of sulfatase genes in the developing mouse embryo.	SULF2 SULF1 ARSG	4.70e-06	13	90	3	20503373
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	DGLUCY EXOSC9 ZNF605 FN1 MYO6 PPRC1 SULF1 ZNF197 HECTD4 LRP2 ZNF224 CARS2 TRIM5 MADD	5.41e-06	1285	90	14	35914814
Pubmed	Cloning and characterization of two extracellular heparin-degrading endosulfatases in mice and humans.	SULF2 SULF1	6.62e-06	2	90	2	12368295
Pubmed	Heparan sulfate 6-O-endosulfatases: discrete in vivo activities and functional co-operativity.	SULF2 SULF1	6.62e-06	2	90	2	16901266
Pubmed	Overexpression of Sulf2 in idiopathic pulmonary fibrosis.	SULF2 SULF1	6.62e-06	2	90	2	23418199
Pubmed	Preferred sites of glycosylphosphatidylinositol modification in folate receptors and constraints in the primary structure of the hydrophobic portion of the signal.	FOLR1 FOLR2	6.62e-06	2	90	2	7578066
Pubmed	Regulation of fractone heparan sulfate composition in young and aged subventricular zone neurogenic niches.	SULF2 SULF1	6.62e-06	2	90	2	34324645
Pubmed	Sulf loss influences N-, 2-O-, and 6-O-sulfation of multiple heparan sulfate proteoglycans and modulates fibroblast growth factor signaling.	SULF2 SULF1	6.62e-06	2	90	2	18687675
Pubmed	Loss of endothelial sulfatase-1 after experimental sepsis attenuates subsequent pulmonary inflammatory responses.	SULF2 SULF1	6.62e-06	2	90	2	31461325
Pubmed	HSulf-1 and HSulf-2 are potent inhibitors of myeloma tumor growth in vivo.	SULF2 SULF1	6.62e-06	2	90	2	16192265
Pubmed	Functional consequences of the subdomain organization of the sulfs.	SULF2 SULF1	6.62e-06	2	90	2	19520866
Pubmed	Epithelial Deletion of Sulf2 Exacerbates Bleomycin-Induced Lung Injury, Inflammation, and Mortality.	SULF2 SULF1	6.62e-06	2	90	2	28657777
Pubmed	The SULFs, extracellular sulfatases for heparan sulfate, promote the migration of corneal epithelial cells during wound repair.	SULF2 SULF1	6.62e-06	2	90	2	23950901
Pubmed	SULF1/SULF2 splice variants differentially regulate pancreatic tumour growth progression.	SULF2 SULF1	6.62e-06	2	90	2	24726914
Pubmed	Folate-binding proteins.	FOLR1 FOLR2	6.62e-06	2	90	2	2166548
Pubmed	Endosulfatases SULF1 and SULF2 limit Chlamydia muridarum infection.	SULF2 SULF1	6.62e-06	2	90	2	23480519
Pubmed	Expression of functional folate receptors in multiple myeloma.	FOLR1 FOLR2	6.62e-06	2	90	2	29616859
Pubmed	Expression of novel extracellular sulfatases Sulf-1 and Sulf-2 in normal and osteoarthritic articular cartilage.	SULF2 SULF1	6.62e-06	2	90	2	18507859
Pubmed	Differential involvement of the extracellular 6-O-endosulfatases Sulf1 and Sulf2 in brain development and neuronal and behavioural plasticity.	SULF2 SULF1	6.62e-06	2	90	2	20394677
Pubmed	Heparan sulfate 6-O-endosulfatases, Sulf1 and Sulf2, regulate glomerular integrity by modulating growth factor signaling.	SULF2 SULF1	6.62e-06	2	90	2	26764203
Pubmed	SULFs in human neoplasia: implication as progression and prognosis factors.	SULF2 SULF1	6.62e-06	2	90	2	21599997
Pubmed	Association of periconceptional folate supplements and FOLR1 and FOLR2 gene polymorphisms with risk of congenital heart disease in offspring: A hospital-based case-control study.	FOLR1 FOLR2	6.62e-06	2	90	2	35545363
Pubmed	SULF1/SULF2 reactivation during liver damage and tumour growth.	SULF2 SULF1	6.62e-06	2	90	2	27013228
Pubmed	[Fibronectin gene polymorphisms and clinical manifestations of mixed cryoglobulinemic syndrome: increased risk of lymphoma associated to MspI DD and HaeIII AA genotypes].	FN1 TFPI2	6.62e-06	2	90	2	18810851
Pubmed	Short SULF1/SULF2 splice variants predominate in mammary tumours with a potential to facilitate receptor tyrosine kinase-mediated cell signalling.	SULF2 SULF1	6.62e-06	2	90	2	27294358
Pubmed	Heparan Sulfate-Editing Extracellular Sulfatases Enhance VEGF Bioavailability for Ischemic Heart Repair.	SULF2 SULF1	6.62e-06	2	90	2	31434553
Pubmed	Extracellular sulfatases support cartilage homeostasis by regulating BMP and FGF signaling pathways.	SULF2 SULF1	6.62e-06	2	90	2	20479257
Pubmed	Multi-tasking Sulf1/Sulf2 enzymes do not only facilitate extracellular cell signalling but also participate in cell cycle related nuclear events.	SULF2 SULF1	6.62e-06	2	90	2	29360432
Pubmed	Mutational analysis of FOLR1 and FOLR2 genes in children with Myelomeningocele.	FOLR1 FOLR2	6.62e-06	2	90	2	37883728
Pubmed	Expression of functional folate receptors by human parathyroid cells.	FOLR1 FOLR2	6.62e-06	2	90	2	24206618
Pubmed	Sulf1 and Sulf2 Differentially Modulate Heparan Sulfate Proteoglycan Sulfation during Postnatal Cerebellum Development: Evidence for Neuroprotective and Neurite Outgrowth Promoting Functions.	SULF2 SULF1	6.62e-06	2	90	2	26448642
Pubmed	Enhanced tumorigenic potential of colorectal cancer cells by extracellular sulfatases.	SULF2 SULF1	6.62e-06	2	90	2	25477293
Pubmed	Diffusion magnetic resonance tractography-based evaluation of commissural fiber abnormalities in a heparan sulfate endosulfatase-deficient mouse brain.	SULF2 SULF1	6.62e-06	2	90	2	35131262
Pubmed	Analysis of sequence variations in the promoter region of the human tissue factor pathway inhibitor 2 gene in apoplectic patients and blood donors.	TFPI2 TFPI	6.62e-06	2	90	2	16247609
Pubmed	Choroid plexus megalin is involved in neuroprotection by serum insulin-like growth factor I.	IGF1R LRP2	6.62e-06	2	90	2	16306401
Pubmed	Organ-specific sulfation patterns of heparan sulfate generated by extracellular sulfatases Sulf1 and Sulf2 in mice.	SULF2 SULF1	6.62e-06	2	90	2	22298771
Pubmed	Abnormal Pyramidal Decussation and Bilateral Projection of the Corticospinal Tract Axons in Mice Lacking the Heparan Sulfate Endosulfatases, Sulf1 and Sulf2.	SULF2 SULF1	6.62e-06	2	90	2	32038163
Pubmed	Folate receptor beta as a potential delivery route for novel folate antagonists to macrophages in the synovial tissue of rheumatoid arthritis patients.	FOLR1 FOLR2	6.62e-06	2	90	2	19116913
Pubmed	Expression of Heparan Sulfate Endosulfatases in the Adult Mouse Brain: Co-expression of Sulf1 and Dopamine D1/D2 Receptors.	SULF2 SULF1	6.62e-06	2	90	2	34489650
Pubmed	Sulfs are regulators of growth factor signaling for satellite cell differentiation and muscle regeneration.	SULF2 SULF1	6.62e-06	2	90	2	17920055
Pubmed	Tissue factor pathway inhibitor gene disruption produces intrauterine lethality in mice.	TFPI2 TFPI	6.62e-06	2	90	2	9242522
Pubmed	5-HT(2B) receptors are required for serotonin-selective antidepressant actions.	HTR2B FEV	1.98e-05	3	90	2	22158014
Pubmed	Increased expression and characterization of two distinct folate binding proteins in murine erythroleukemia cells.	FOLR1 FOLR2	1.98e-05	3	90	2	8304978
Pubmed	Characterization of two cDNAs encoding folate-binding proteins from L1210 murine leukemia cells. Increased expression associated with a genomic rearrangement.	FOLR1 FOLR2	1.98e-05	3	90	2	1894617
Pubmed	WT1-dependent sulfatase expression maintains the normal glomerular filtration barrier.	SULF2 SULF1	1.98e-05	3	90	2	21719793
Pubmed	Identification of amino acid residues that determine the differential ligand specificities of folate receptors alpha and beta.	FOLR1 FOLR2	1.98e-05	3	90	2	9166787
Pubmed	Characterization of organic anion transporting polypeptide 1b2-null mice: essential role in hepatic uptake/toxicity of phalloidin and microcystin-LR.	SLCO1B7 SLCO1B3	1.98e-05	3	90	2	18296417
Pubmed	Genomic organization of the human folate receptor genes on chromosome 11q13.	FOLR1 FOLR2	1.98e-05	3	90	2	1330883
Pubmed	Interaction Between Sex and Organic Anion-Transporting Polypeptide 1b2 on the Pharmacokinetics of Regorafenib and Its Metabolites Regorafenib-N-Oxide and Regorafenib-Glucuronide in Mice.	SLCO1B7 SLCO1B3	1.98e-05	3	90	2	30955241
Pubmed	Nuclear factor of activated T cells mediates RhoA-induced fibronectin upregulation in glomerular podocytes.	FN1 NFATC1	1.98e-05	3	90	2	23389455
Pubmed	Influence of drug formulation on OATP1B-mediated transport of paclitaxel.	SLCO1B7 SLCO1B3	1.98e-05	3	90	2	24755470
Pubmed	OATP1B2 deficiency protects against paclitaxel-induced neurotoxicity.	SLCO1B7 SLCO1B3	1.98e-05	3	90	2	29337310
Pubmed	Expression of Oatp2 in the Brain and Liver of Alzheimer Disease Mouse Model.	SLCO1B7 SLCO1B3	1.98e-05	3	90	2	31967785
Pubmed	A new Adamts9 conditional mouse allele identifies its non-redundant role in interdigital web regression.	ADAMTS20 ADAMTS5	1.98e-05	3	90	2	24753090
Pubmed	Gene trap disruption of the mouse heparan sulfate 6-O-endosulfatase gene, Sulf2.	SULF2 SULF1	1.98e-05	3	90	2	17116694
Pubmed	Expression of the heparan sulfate 6-O-endosulfatases, Sulf1 and Sulf2, in the avian and mammalian inner ear suggests a role for sulfation during inner ear development.	SULF2 SULF1	1.98e-05	3	90	2	25370455
Pubmed	IGF-1R Reduction Triggers Neuroprotective Signaling Pathways in Spinal Muscular Atrophy Mice.	IGF1R SMN1	1.98e-05	3	90	2	26311784
Pubmed	Renal tubular reabsorption of folate mediated by folate binding protein 1.	FOLR1 FOLR2	1.98e-05	3	90	2	15703271
Pubmed	Role of the murine organic anion-transporting polypeptide 1b2 (Oatp1b2) in drug disposition and hepatotoxicity.	SLCO1B7 SLCO1B3	1.98e-05	3	90	2	18492796
Pubmed	Differential Expression of OATP1B3 Mediates Unconjugated Testosterone Influx.	SLCO1B7 SLCO1B3	1.98e-05	3	90	2	28389619
Pubmed	Organic anion transporting polypeptide 1B transporters modulate hydroxyurea pharmacokinetics.	SLCO1B7 SLCO1B3	1.98e-05	3	90	2	23986199
Pubmed	Targeted disruption of murine organic anion-transporting polypeptide 1b2 (Oatp1b2/Slco1b2) significantly alters disposition of prototypical drug substrates pravastatin and rifampin.	SLCO1B7 SLCO1B3	1.98e-05	3	90	2	18413659
Pubmed	Cav2.2-NFAT2-USP43 axis promotes invadopodia formation and breast cancer metastasis through cortactin stabilization.	CACNA1B NFATC1	1.98e-05	3	90	2	36137995
Pubmed	Developmental consequences of in utero sodium arsenate exposure in mice with folate transport deficiencies.	FOLR1 FOLR2	1.98e-05	3	90	2	15694460
Pubmed	Organic anion-transporting polypeptide 1b2 (Oatp1b2) is important for the hepatic uptake of unconjugated bile acids: Studies in Oatp1b2-null mice.	SLCO1B7 SLCO1B3	1.98e-05	3	90	2	20949553
Pubmed	Heparan sulfate 6-O-endosulfatases (Sulfs) coordinate the Wnt signaling pathways to regulate myoblast fusion during skeletal muscle regeneration.	SULF2 SULF1	1.98e-05	3	90	2	22865881
Pubmed	Expression patterns of folate binding proteins one and two in the developing mouse embryo.	FOLR1 FOLR2	1.98e-05	3	90	2	9973545
Pubmed	Mice lacking the folic acid-binding protein Folbp1 are defective in early embryonic development.	FOLR1 FOLR2	1.98e-05	3	90	2	10508523
Pubmed	Desulfation of Heparan Sulfate by Sulf1 and Sulf2 Is Required for Corticospinal Tract Formation.	SULF2 SULF1	1.98e-05	3	90	2	29062064
Pubmed	Sulf1 and Sulf2 expression in the nervous system and its role in limiting neurite outgrowth in vitro.	SULF2 SULF1	1.98e-05	3	90	2	25448158
Pubmed	Identification, expression, and functional characterization of full-length and splice variants of murine organic anion transporting polypeptide 1b2.	SLCO1B7 SLCO1B3	1.98e-05	3	90	2	19400585
Pubmed	Synergistic interaction between genetics and disease on pravastatin disposition.	SLCO1B7 SLCO1B3	1.98e-05	3	90	2	24613363
Pubmed	Full-length cDNA cloning and genomic organization of the mouse liver-specific organic anion transporter-1 (lst-1).	SLCO1B7 SLCO1B3	1.98e-05	3	90	2	10833452
Pubmed	Impact of Oatp1c1 deficiency on thyroid hormone metabolism and action in the mouse brain.	SLCO1B7 SLCO1B3	3.96e-05	4	90	2	22294745
Pubmed	Secreted sulfatases Sulf1 and Sulf2 have overlapping yet essential roles in mouse neonatal survival.	SULF2 SULF1	3.96e-05	4	90	2	17593974
Pubmed	Growing Mouse Oocytes Transiently Activate Folate Transport via Folate Receptors As They Approach Full Size.	FOLR1 FOLR2	3.96e-05	4	90	2	27122634
Pubmed	Binding of internalized receptors to the PDZ domain of GIPC/synectin recruits myosin VI to endocytic vesicles.	MYO6 LRP2	3.96e-05	4	90	2	16908842
Pubmed	Organic anion transporting polypeptide 1a/1b-knockout mice provide insights into hepatic handling of bilirubin, bile acids, and drugs.	SLCO1B7 SLCO1B3	3.96e-05	4	90	2	20644253
Pubmed	Identification of two putative novel folate receptor genes in humans and mouse.	FOLR1 FOLR2	3.96e-05	4	90	2	11111049
Pubmed	Protection against phalloidin-induced liver injury by oleanolic acid involves Nrf2 activation and suppression of Oatp1b2.	SLCO1B7 SLCO1B3	3.96e-05	4	90	2	25280775
Pubmed	Distinct expression patterns of Sulf1 and Hs6st1 spatially regulate heparan sulfate sulfation during prostate development.	SULF2 SULF1	3.96e-05	4	90	2	23074159
Pubmed	Expression of folate receptors alpha and beta in normal and cancerous gynecologic tissues: correlation of expression of the beta isoform with macrophage markers.	FOLR1 FOLR2	3.96e-05	4	90	2	25971554
Pubmed	Mutations in folate transporter genes and risk for human myelomeningocele.	FOLR1 FOLR2	3.96e-05	4	90	2	28948692
Pubmed	HSulf sulfatases catalyze processive and oriented 6-O-desulfation of heparan sulfate that differentially regulates fibroblast growth factor activity.	SULF2 SULF1	3.96e-05	4	90	2	23457216
Pubmed	Expression regulation and function of heparan sulfate 6-O-endosulfatases in the spermatogonial stem cell niche.	SULF2 SULF1	3.96e-05	4	90	2	20855470
Pubmed	Association of folate receptor (FOLR1, FOLR2, FOLR3) and reduced folate carrier (SLC19A1) genes with meningomyelocele.	FOLR1 FOLR2	3.96e-05	4	90	2	20683905
Pubmed	Contribution of Organic Anion-Transporting Polypeptides 1A/1B to Doxorubicin Uptake and Clearance.	SLCO1B7 SLCO1B3	3.96e-05	4	90	2	27777271
Pubmed	O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.	ADAMTS6 ADAMTS20 SEMA5A ADAMTS5	4.43e-05	75	90	4	20637190
Pubmed	OATP1A/1B transporters affect irinotecan and SN-38 pharmacokinetics and carboxylesterase expression in knockout and humanized transgenic mice.	SLCO1B7 SLCO1B3	6.59e-05	5	90	2	24194565
Pubmed	Roles of heparan sulfate sulfation in dentinogenesis.	SULF2 SULF1	6.59e-05	5	90	2	22351753
Pubmed	Sulfatase modifying factor 1-mediated fibroblast growth factor signaling primes hematopoietic multilineage development.	SULF2 SULF1	6.59e-05	5	90	2	20643830
Pubmed	Fine-mapping quantitative trait loci affecting murine external ear tissue regeneration in the LG/J by SM/J advanced intercross line.	FN1 ADAMTS6 RDM1	8.64e-05	33	90	3	24569637
Pubmed	Complete OATP1B1 and OATP1B3 deficiency causes human Rotor syndrome by interrupting conjugated bilirubin reuptake into the liver.	SLCO1B7 SLCO1B3	9.87e-05	6	90	2	22232210
Pubmed	Genetic control of sensitivity to hippocampal cell death induced by kainic acid: a quantitative trait loci analysis.	NFATC1 SEMA5A	9.87e-05	6	90	2	15281082
Pubmed	Analysis of DNA methylation and histone modification profiles of liver-specific transporters.	SLCO1B7 SLCO1B3	9.87e-05	6	90	2	19047482
Pubmed	Megalin-mediated endocytosis of cystatin C in proximal tubule cells.	CST5 LRP2	9.87e-05	6	90	2	17462596
Pubmed	Folate transport in mouse cumulus-oocyte complexes and preimplantation embryos.	FOLR1 FOLR2	9.87e-05	6	90	2	23904512
Pubmed	Galnt1 is required for normal heart valve development and cardiac function.	FN1 ADAMTS20 ADAMTS5	1.12e-04	36	90	3	25615642
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	EML5 FN1 DDX50 UBE2Q1 BAZ1A PPRC1 ETS1 LRP2 TRIM5 MADD NPNT	1.13e-04	1084	90	11	11544199
GeneFamily	Sulfatases	SULF2 SULF1 ARSG	5.35e-05	18	75	3	410
GeneFamily	ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS6 ADAMTS20 ADAMTS5	6.33e-05	19	75	3	50
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	HPR CSMD3 SVEP1	1.71e-03	57	75	3	1179
GeneFamily	Aminoacyl tRNA synthetases, Class I	CARS2 YARS2	2.77e-03	19	75	2	131
Coexpression	GSE5679_CTRL_VS_RARA_AGONIST_AM580_TREATED_DC_DN	NTN4 TUT4 FBXO22 GIMAP8 EML5 ZNF862 ETS1	5.50e-06	200	89	7	M6556
Coexpression	NABA_ECM_REGULATORS	SULF2 ADAMTS6 SULF1 CST5 ADAMTS20 ADAMTS5 CTSZ	1.71e-05	238	89	7	M3468
Coexpression	NABA_ECM_REGULATORS	SULF2 ADAMTS6 SULF1 CST5 ADAMTS20 ADAMTS5 CTSZ	1.90e-05	242	89	7	MM17062
Coexpression	NABA_MATRISOME	NTN4 SULF2 FN1 ADAMTS6 SULF1 CST5 ADAMTS20 CDCP2 SEMA5A ADAMTS5 CTSZ SVEP1 NPNT	3.49e-05	1008	89	13	MM17056
Coexpression	NABA_MATRISOME	NTN4 SULF2 FN1 ADAMTS6 SULF1 CST5 ADAMTS20 CDCP2 SEMA5A ADAMTS5 CTSZ SVEP1 NPNT	4.19e-05	1026	89	13	M5889
Coexpression	DESCARTES_ORGANOGENESIS_EPENDYMAL_CELL	SLCO1B7 RSPH4A FOLR1 FOLR2 CCNO SLCO1B3 ARSG	5.03e-05	282	89	7	MM3642
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-neuronal_stem_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPN4 FOLR2 EML6 DHX57 SEMA5A ADAMTS5 ALG13	4.54e-08	165	90	7	1703d3eb644b3c743ad3c5532b1d29ea010c79c8
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FN1 SULF1 SEMA5A ADAMTS5 CSMD3 SVEP1 TFPI	1.37e-07	194	90	7	5f5f0cdeacd5e1b28717d78dabdb9eb95f661e36
ToppCell	10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-osteochondral_precursor\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	FN1 TFPI2 SULF1 SEMA5A IGLON5 SVEP1 TFPI	1.52e-07	197	90	7	c165c6fd12dc649b39e920d8528e2eb65c61956b
ToppCell	droplet-Fat-SCAT-30m-Lymphocytic-T_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LY6G5B PTPN4 SPINT2 ZBTB25 CCNO PGM2L1	1.61e-06	177	90	6	baf78a8dad55f124f56585f88b10b58c0269680f
ToppCell	LA-01._Fibroblast_I\|World / Chamber and Cluster_Paper	FN1 SULF1 PLA2G5 ADAMTS5 SVEP1 TFPI	2.22e-06	187	90	6	4ea486991f66c29728d127171a07b81404ec0b78
ToppCell	LV-02._Fibroblast_II\|LV / Chamber and Cluster_Paper	FN1 SULF1 PLA2G5 ADAMTS5 SVEP1 TFPI	2.74e-06	194	90	6	014d2feb5db2a6a35ef759761a41e466e108c3c1
ToppCell	COVID-19-Heart-Fib_1\|Heart / Disease (COVID-19 only), tissue and cell type	FN1 SULF1 PLA2G5 ADAMTS5 SVEP1 TFPI	2.82e-06	195	90	6	f423baa36ac7cdc383c033e35a7d17e6bf913323
ToppCell	LA-02._Fibroblast_II\|World / Chamber and Cluster_Paper	FN1 SULF1 PLA2G5 ADAMTS5 SVEP1 TFPI	2.82e-06	195	90	6	a78b605b49acd8c9d68716266ca269dafcd910b9
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RAB34 FN1 TFPI2 SULF1 CSMD3 TFPI	2.99e-06	197	90	6	236a40eb6c08e1d179cf0fb5450b032975c5f6b6
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Mesenchymal-BMP_responsible_cell\|6m / Sample Type, Dataset, Time_group, and Cell type.	SPINT2 RSPH4A FOLR1 TFPI2 SULF1 TRPM1	3.27e-06	200	90	6	5fb90118d3abc28d72bc483e68317255090a04c7
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NTN4 TFPI2 LRP2 SEMA5A ALDH4A1 TFPI	3.27e-06	200	90	6	105564ee05bd11685b5747ee32d5350cf3c2e2e1
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RAB34 FN1 SEMA5A ADAMTS5 SVEP1 TFPI	3.27e-06	200	90	6	ac8a5d71acd4d401995babd233f0d3738e8ad2a5
ToppCell	COVID-19-kidney-Technical/muscle_(Mes)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CACNA1B WDR64 SPATA16 ADAMTS20 CSMD3	1.26e-05	148	90	5	d6ac5972267254651dfbe16bb4e9a62228093cc7
ToppCell	COVID-19-kidney-Technical/muscle_(Imm)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CACNA1B WDR64 SPATA16 ADAMTS20 CSMD3	1.35e-05	150	90	5	0205318a870e091add66ee4305747dda9f51510d
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1B WDR64 SULF1 LRP2 SVEP1	1.84e-05	160	90	5	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1B WDR64 SULF1 LRP2 SVEP1	1.84e-05	160	90	5	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SULF2 GIMAP8 MYO6 KLHL30 ETS1	2.07e-05	164	90	5	e712d6b89461f741dbd773ba9a27ecaddf97cbaa
ToppCell	LV-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	NTN4 SPINT2 OBP2A PLA2G5 NPNT	2.13e-05	165	90	5	f37fd95adc95d7753cf6e55ae819976513c7ec77
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PTPN4 EXOSC9 ETS1 MDGA1 RAVER1	2.20e-05	166	90	5	ceb0a48c0d853448fd45ac31dde046df9a178571
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FN1 TFPI2 SULF1 CSMD3 TFPI	2.46e-05	170	90	5	b5b47fe42617a4c2ebb49c8ed55db3926213a75a
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	OBP2A FOLR1 TFPI2 CST5 NPNT	2.53e-05	171	90	5	fd59ac4a39748840b2ee1c930ea475433ff61485
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2-Transitional_Club-AT2_L.0.4.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	OBP2A FOLR1 TFPI2 CST5 NPNT	2.53e-05	171	90	5	d5960b40ad5b87aaa00c93a6b31cdf41cc4f1375
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-epithelial_cell_of_lung\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	OBP2A FOLR1 TFPI2 CST5 NPNT	2.53e-05	171	90	5	d382430e5cdd0f2aac4fc093d8fe8d66efb4629b
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	OBP2A FOLR1 TFPI2 CST5 NPNT	2.53e-05	171	90	5	4347e6f62c04ea43299893ad4b79719049009a56
ToppCell	LV-13._Vascular_Smooth_Muscle\|LV / Chamber and Cluster_Paper	NTN4 SPINT2 FN1 PLA2G5 NPNT	2.53e-05	171	90	5	e99ecae66530d1ae09330cee408c8f3950b87e67
ToppCell	11.5-Airway-Epithelial-Basal_cell\|Airway / Age, Tissue, Lineage and Cell class	HTR2B SPINT2 TFPI2 CCNO NPNT	2.60e-05	172	90	5	9d4d92e2d16dfc8a394f2641653bb97de20a2530
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	RAB23 FN1 NFATC1 SULF1 SVEP1	2.91e-05	176	90	5	9bc87cd5cda2372e1bce94c9dfd408eb1dfd8d0c
ToppCell	PND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SULF2 KLHL30 FOLR1 SULF1 LRP2	2.91e-05	176	90	5	8e7f38de8bf68077e2138f4d06c1f55b0fd096cc
ToppCell	PND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SULF2 KLHL30 FOLR1 SULF1 LRP2	2.91e-05	176	90	5	ed575330a08a6748ea4b28433292c8cfd157d444
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	RAB23 FN1 NFATC1 SULF1 SVEP1	2.91e-05	176	90	5	3f8274a7ab67f9f8a8923193763a5543cfe4defa
ToppCell	Frontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Nptxr-Excitatory_Neuron.Slc17a7.Nptxr-Drd1_(Deep_layer_pyramidal_cells)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	SART3 PANK2 PPRC1 FOLR2 ALG13	2.91e-05	176	90	5	3c76a5c4ca2b378667cb155fbb9675519572b35d
ToppCell	LPS-antiTNF-Epithelial_alveolar-Mes-like-AT1_Progenitor\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1B B3GALT6 RDM1 ALDH4A1 SVEP1	2.99e-05	177	90	5	164ffbbf798defa3728197deb1a14b661490e525
ToppCell	P28-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SULF2 SPINT2 FOLR1 SULF1 LRP2	3.07e-05	178	90	5	1e05bc26591fea16e29bcfc5f538dda1dc427f05
ToppCell	10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-early_osteoblast\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	FN1 FOLR1 SEMA5A SVEP1 NPNT	3.07e-05	178	90	5	e32f5ed7a492edfa7073416008b1fcfae6b854ad
ToppCell	390C-Epithelial_cells-Epithelial-B_(AT2)\|390C / Donor, Lineage, Cell class and subclass (all cells)	NTN4 SPINT2 FOLR1 LRP2 TFPI	3.15e-05	179	90	5	466da2bc3bfc534ffe111c8c28ece7a3cfa08051
ToppCell	390C-Epithelial_cells-Epithelial-B_(AT2)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	NTN4 SPINT2 FOLR1 LRP2 TFPI	3.15e-05	179	90	5	f4bdebb77d39e63160fbf3a85a340ce4d52b7cfd
ToppCell	facs-Diaphragm-Limb_Muscle-3m-Lymphocytic-T_cell\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LY6G5B GIMAP8 SPINT2 ETS1 MADD	3.15e-05	179	90	5	8bf04a7ad1b0be6722ebfdceba3f083f07bf96c5
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HTR2B FN1 SULF1 ADAMTS5 SVEP1	3.32e-05	181	90	5	c6d2a13df3b74fade3b0c71e285b4c14c8e52413
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HTR2B FN1 SULF1 ADAMTS5 SVEP1	3.32e-05	181	90	5	c62b0a2422377ffadaab63edd538e87a06fa5017
ToppCell	facs-GAT-Fat-3m-Lymphocytic-T_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LY6G5B GIMAP8 ETS1 PGM2L1 NPNT	3.41e-05	182	90	5	751bd3e3b49de961523e98197688a05c998c121a
ToppCell	droplet-Marrow-nan-3m-Hematologic-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TUT4 GIMAP8 MYO6 EML4 ETS1	3.41e-05	182	90	5	e78ba2c5cae480c16a596ce7c3bf2d480becacf4
ToppCell	droplet-Marrow-nan-3m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TUT4 GIMAP8 MYO6 EML4 ETS1	3.41e-05	182	90	5	1710eab3037a87609d21838be2d2d29c3bc36651
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ASIC1 FOLR1 SULF1 LRP2 ADAMTS5	3.41e-05	182	90	5	9966f42c338cbd471efa8ffc765a6ce93693aa75
ToppCell	10x3'2.3-week_17-19-Mesenchymal_osteo-stroma-early_osteoblast\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	FN1 MYO6 FOLR1 SEMA5A NPNT	3.50e-05	183	90	5	27a57cd8ea924420e182f3d72f5b29b00dea8fa0
ToppCell	E15.5-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FOLR1 SULF1 LRP2 ADAMTS5 NPNT	3.50e-05	183	90	5	274f274cf60daa30d6a4cd603a3af7823bfb8016
ToppCell	COVID-19-Heart-Fib_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FN1 SULF1 PLA2G5 ADAMTS5 SVEP1	3.69e-05	185	90	5	8f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NTN4 IGF1R AGMO LRP2 SEMA5A	3.88e-05	187	90	5	9d77ca45f7563bd6f2a0c1be5d99d93ad30983f7
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma-6\|TCGA-Breast / Sample_Type by Project: Shred V9	NTN4 SULF2 FN1 ADAMTS6 SULF1	3.88e-05	187	90	5	a96495803ba13fcfadd1d83b3cf5774f3fed0a20
ToppCell	10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-osteochondral_precursor\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	FN1 MYO6 TFPI2 TFPI NPNT	3.98e-05	188	90	5	ed92cddf47defea2f904d36c7ae05ffa323349a9
ToppCell	10x3'2.3-week_17-19-Mesenchymal_osteo-stroma-osteochondral_precursor\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	FN1 SULF1 SEMA5A SVEP1 TFPI	4.08e-05	189	90	5	1ff4f8da572bdc6356e9df9f41a7f62c81d4c570
ToppCell	RA-10._Endothelium_II\|World / Chamber and Cluster_Paper	SULF2 FN1 ETS1 PLA2G5 TFPI	4.08e-05	189	90	5	75c248b9de5e2fb7a0baa8cdbab516e575cc4394
ToppCell	3'-GW_trimst-1-LargeIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NTN4 GIMAP8 TFPI2 SULF1 TFPI	4.19e-05	190	90	5	92fdfed12061ee9f6c7171cf8a7f3344921f2d40
ToppCell	Fibroblasts-CD55+_Fibroblasts\|Fibroblasts / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	NTN4 FN1 EML6 SEMA5A ADAMTS5	4.19e-05	190	90	5	b4088128f5acf53f43244c9af9fe44e033f1a57a
ToppCell	3'_v3-bone_marrow-Myeloid_Dendritic\|bone_marrow / Manually curated celltypes from each tissue	SULF2 SPINT2 SEMA5A CTSZ LILRA4	4.19e-05	190	90	5	6892c603037b61ef88d6ca01b7592dc0d347d63b
ToppCell	343B-Endothelial_cells-Endothelial-B_(Artery)\|343B / Donor, Lineage, Cell class and subclass (all cells)	SULF2 GIMAP8 FN1 SULF1 PLA2G5	4.29e-05	191	90	5	27a532a35d9e8822014f581fd56c4ca62e39f8fe
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.4.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NTN4 FN1 SVEP1 TFPI NPNT	4.29e-05	191	90	5	f00d6824bd138b192a996e9f7de57b235bb24c18
ToppCell	LV-02._Fibroblast_II\|World / Chamber and Cluster_Paper	SULF1 PLA2G5 ADAMTS5 SVEP1 TFPI	4.29e-05	191	90	5	d36565257ccba8c1bbed2c1c01be66a9cbb5f834
ToppCell	COVID-19-Lymphoid-pDC\|COVID-19 / Condition, Lineage and Cell class	SULF2 WDR64 SPINT2 IGLON5 LILRA4	4.29e-05	191	90	5	25343b11d42128ad16659e5519cd1673266cc505
ToppCell	343B-Endothelial_cells-Endothelial-B_(Artery)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	SULF2 GIMAP8 FN1 SULF1 PLA2G5	4.29e-05	191	90	5	1dfcff08e01e6a695953334342bcfde04ba005ad
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FN1 ASIC1 SULF1 HPR SVEP1	4.40e-05	192	90	5	f88aba74d6e8c594c32fe2bc095b5da28b4b28e9
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SULF2 FN1 SEMA5A ADAMTS5 SVEP1	4.40e-05	192	90	5	beac6b3c191b11add8e39e8d04562b478ea8929e
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive\|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	NFATC1 BAZ1A PPRC1 EML4 ETS1	4.40e-05	192	90	5	8b86db2ebe0199fee0e9800566a619a24bfdeed5
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FN1 ASIC1 SULF1 HPR SVEP1	4.40e-05	192	90	5	41a8326cd5bc19ad5041068501bab4c72399222e
ToppCell	BLOOD--(3)_DC_(cDC+pDC)\| / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	SULF2 SPINT2 RAB34 CTSZ LILRA4	4.40e-05	192	90	5	e290c55a1321e9e577f49e8ba20501b2c8150044
ToppCell	RV-10._Endothelium_II\|RV / Chamber and Cluster_Paper	SULF2 FN1 ETS1 PLA2G5 TFPI	4.51e-05	193	90	5	01c2df9206f1527c578e808978e58196c35e72f5
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NTN4 SPINT2 SEMA5A TFPI NPNT	4.51e-05	193	90	5	ffa1932da2979d7b63dbac32eb5788346a3f5b2a
ToppCell	ILEUM-inflamed-(8)_Smooth_muscle_cells\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	FN1 SULF1 SEMA5A ADAMTS5 NPNT	4.51e-05	193	90	5	084c88f08ce0ecd6c9f4334caed370eb2154f896
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FN1 TFPI2 SULF1 SEMA5A CSMD3	4.51e-05	193	90	5	68089ba4123e2f9bea9aae0023a844b5a57bfc0e
ToppCell	LV-01._Fibroblast_I\|LV / Chamber and Cluster_Paper	SULF1 PLA2G5 ADAMTS5 SVEP1 TFPI	4.51e-05	193	90	5	dc17f3b9758936d428cf17f77a1ce6d4c479b165
ToppCell	RV-02._Fibroblast_II\|RV / Chamber and Cluster_Paper	FN1 PLA2G5 ADAMTS5 SVEP1 TFPI	4.62e-05	194	90	5	11c79a8c56ece42713b04b321982e41e239f07a5
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Mesenchymal\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	NFATC1 FOLR1 SULF1 ETS1 CCNO	4.62e-05	194	90	5	638b9fdce64ed00243b5303800ec66207d5fd640
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Mesenchymal-choroid_plexus/mesenchymal-like_cells\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	NFATC1 FOLR1 SULF1 ETS1 CCNO	4.62e-05	194	90	5	e9868c22934b6c0ac35e3e8270ec0b671bc6582a
ToppCell	COVID-19-Heart-Fib_2\|Heart / Disease (COVID-19 only), tissue and cell type	FN1 SULF1 ADAMTS5 SVEP1 TFPI	4.62e-05	194	90	5	d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HTR2B FN1 SULF1 HPR SVEP1	4.62e-05	194	90	5	02b8102be9414d6964cd71019613edff6d88b893
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HTR2B FN1 SULF1 HPR SVEP1	4.62e-05	194	90	5	29f83cdd63314fff41258937d70b881a5503bfcc
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HTR2B FN1 SULF1 HPR SVEP1	4.62e-05	194	90	5	d3db241ea316bbcde6d16618193b474591ad5ce4
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NTN4 SPINT2 LRP2 TFPI NPNT	4.62e-05	194	90	5	8ddcaaf24cee6e30d5be52c0cbf778cfba309c53
ToppCell	LA-02._Fibroblast_II\|LA / Chamber and Cluster_Paper	FN1 PLA2G5 ADAMTS5 SVEP1 TFPI	4.62e-05	194	90	5	234d1494c114cce77c619708bbcd8d5ce805f19b
ToppCell	356C-Epithelial_cells-Epithelial-I_(AT1)\|356C / Donor, Lineage, Cell class and subclass (all cells)	FOLR1 CST5 SEMA5A MDGA1 NPNT	4.74e-05	195	90	5	07a3ef6b0f1201fe2bcb9ea426b8f7a69beb4904
ToppCell	normal_Lung-Epithelial_cells-AT1\|normal_Lung / Location, Cell class and cell subclass	SPINT2 FOLR1 CST5 SEMA5A NPNT	4.74e-05	195	90	5	569d1ebc5a5aa110a2430b096755ae35354040c4
ToppCell	356C-Epithelial_cells-Epithelial-I_(AT1)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	FOLR1 CST5 SEMA5A MDGA1 NPNT	4.74e-05	195	90	5	b65511770ed67f7447847e2187555b362988af45
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PTPN4 TUT4 EML4 ETS1 ALG13	4.74e-05	195	90	5	ed5f772c82d4dfd1c8735224446ec9feae3fb8c2
ToppCell	15-Trachea-Mesenchymal\|Trachea / Age, Tissue, Lineage and Cell class	FN1 SULF1 SEMA5A ADAMTS5 SVEP1	4.85e-05	196	90	5	7e178c76285e61c721c38d7a995ebf89dc428f9f
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GIMAP8 ADAMTS6 SULF1 PLA2G5 TFPI	4.85e-05	196	90	5	cf7f384c1771274e766bab03ecc3dfbd13f2df60
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NTN4 SULF2 ASIC1 SEMA5A CSMD3	4.85e-05	196	90	5	f374cb3ec31c6eef2cef9e07547bfd1e380553af
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NTN4 SULF2 ASIC1 SEMA5A CSMD3	4.85e-05	196	90	5	671c380b58d7f634b4fbec38c357d357ea4f3535
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Dendritic\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SULF2 SPINT2 RAB34 CTSZ LILRA4	4.97e-05	197	90	5	89fe4885efc8db142c0dc0506840ae8aceba9ef9
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma\|TCGA-Pancreas / Sample_Type by Project: Shred V9	SULF2 BAZ1A SULF1 PGM2L1 TFPI	4.97e-05	197	90	5	d8355f07a53e771052f9ab6b38814365dfe8d9ae
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-E\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PTPN4 SULF2 SEMA5A ADAMTS5 CSMD3	4.97e-05	197	90	5	b8dc192fc98428bbb701cc2ea57fc8ad93397785
ToppCell	(5)_Fibroblasts-(5)_Fibroblast-G\|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)	SPINT2 FN1 SVEP1 TFPI NPNT	4.97e-05	197	90	5	a21a710c824f9e5c7ef1674168d1ce5aef85bd35
ToppCell	distal-mesenchymal-Vascular_Smooth_Muscle\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	NTN4 KLHL30 SEMA5A ADAMTS5 NPNT	5.09e-05	198	90	5	8d1c74a728040386316fbdcabcdea5fb2b5a76a1
ToppCell	distal-Endothelial-Artery-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SULF2 GIMAP8 SULF1 PLA2G5 TFPI	5.09e-05	198	90	5	f284f59f4ebe55ee132eddfaa2f5d9ecb059654f
ToppCell	distal-mesenchymal-Vascular_Smooth_Muscle-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	NTN4 KLHL30 SEMA5A ADAMTS5 NPNT	5.09e-05	198	90	5	5080767ff55326b7d94fca27d398237c4a15c1ed
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RAB34 FN1 TFPI2 SULF1 TFPI	5.09e-05	198	90	5	75d104eead681f6bf47c4dd24913cc768c9a1717
ToppCell	ILEUM-non-inflamed-(8)_Fibroblasts\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	FN1 SULF1 ADAMTS5 SVEP1 TFPI	5.22e-05	199	90	5	d9d7f36b4b5592b7855448730044c90997b55499
ToppCell	distal-Endothelial-Artery\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SULF2 GIMAP8 SULF1 PLA2G5 TFPI	5.22e-05	199	90	5	b6e9aaac047d4b64b9d97f5e174e89a424d8b36d
ToppCell	medial-Endothelial-Artery\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SULF2 GIMAP8 SULF1 PLA2G5 TFPI	5.22e-05	199	90	5	341c0be18bec66f4cc8bda232dce54edb34b9cda
ToppCell	Tracheal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_systemic_arterial\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	GIMAP8 FN1 ADAMTS6 SULF1 AGMO	5.22e-05	199	90	5	bd43a84e84d8acb8e1008b98a235cc5bd5f43586
ToppCell	medial-2-Endothelial-Artery\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SULF2 GIMAP8 SULF1 PLA2G5 TFPI	5.22e-05	199	90	5	53c17c0493f82351a039bc64def191311e0f4951
ToppCell	ASK428-Epithelial\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	NTN4 SPINT2 FOLR1 TFPI NPNT	5.22e-05	199	90	5	ba2aaaeb4d9b448a6b9660b152fcac1a0e3fcfe7
Drug	Tenoxicam [59804-37-4]; Down 200; 11.8uM; PC3; HT_HG-U133A	TUT4 SULF1 LRP2 CCNO ALDH4A1 TRPM1 ADAMTS5 SVEP1 LILRA4	7.92e-08	197	89	9	4102_DN
Disease	Iniencephaly	SPINT2 FOLR1 FOLR2	8.23e-05	28	89	3	C0152234
Disease	Tethered Cord Syndrome	SPINT2 FOLR1 FOLR2	8.23e-05	28	89	3	C0080218
Disease	Spinal Cord Myelodysplasia	SPINT2 FOLR1 FOLR2	8.23e-05	28	89	3	C0344479
Disease	Exencephaly	SPINT2 FOLR1 FOLR2	8.23e-05	28	89	3	C0266453
Disease	Neurenteric Cyst	SPINT2 FOLR1 FOLR2	8.23e-05	28	89	3	C0027806
Disease	Acrania	SPINT2 FOLR1 FOLR2	8.23e-05	28	89	3	C0702169
Disease	Diastematomyelia	SPINT2 FOLR1 FOLR2	8.23e-05	28	89	3	C0011999
Disease	bilirubin metabolic disorder (implicated_via_orthology)	SLCO1B7 SLCO1B3	8.94e-05	5	89	2	DOID:2741 (implicated_via_orthology)
Disease	Craniorachischisis	SPINT2 FOLR1 FOLR2	9.16e-05	29	89	3	C0152426
Disease	Neural Tube Defects	SPINT2 FOLR1 FOLR2	1.02e-04	30	89	3	C0027794
Disease	hyperuricemia	IGF1R NFATC1 LRP2	1.36e-04	33	89	3	EFO_0009104
Disease	osteoarthritis (is_marker_for)	IGF1R FN1 ADAMTS5	1.62e-04	35	89	3	DOID:8398 (is_marker_for)
Disease	diabetes mellitus (is_marker_for)	IGF1R FN1 TFPI	2.60e-04	41	89	3	DOID:9351 (is_marker_for)
Disease	hexadecenedioate (C16:1-DC) measurement	SLCO1B7 SLCO1B3	3.19e-04	9	89	2	EFO_0800562
Disease	cholestasis (biomarker_via_orthology)	SLCO1B7 HPR SLCO1B3	4.42e-04	49	89	3	DOID:13580 (biomarker_via_orthology)
Disease	heart rate	NFATC1 AGMO PPIL1 ATE1 TFPI	6.08e-04	225	89	5	EFO_0004326
Disease	neuritic plaque measurement	SULF2 SULF1 SPATA16 AGMO ATE1 SVEP1	6.68e-04	349	89	6	EFO_0006798
Disease	glycochenodeoxycholate glucuronide (1) measurement	SLCO1B7 SLCO1B3	6.87e-04	13	89	2	EFO_0800474
Disease	acute kidney failure (biomarker_via_orthology)	IGF1R FN1 HPR	8.41e-04	61	89	3	DOID:3021 (biomarker_via_orthology)
Disease	response to peritoneal dialysis, peritoneal solute transfer rate	NFATC1 BAZ1A	9.21e-04	15	89	2	EFO_0600089, EFO_0600090
Disease	X-21441 measurement	SLCO1B7 SLCO1B3	1.19e-03	17	89	2	EFO_0800814
Disease	cystatin C measurement	USP5 FBXO22 IGF1R HECTD4 CST5 LRP2	1.38e-03	402	89	6	EFO_0004617
Disease	aspartate aminotransferase measurement	DGLUCY PANK2 ADAMTS6 HPR HECTD4 SLCO1B3 CARS2 TRIM5 MADD	1.63e-03	904	89	9	EFO_0004736
Disease	IgA glomerulonephritis (is_marker_for)	FCAR FN1	1.65e-03	20	89	2	DOID:2986 (is_marker_for)
Disease	osteoarthritis (biomarker_via_orthology)	NFATC1 ADAMTS5	1.82e-03	21	89	2	DOID:8398 (biomarker_via_orthology)
Disease	HbA1c measurement, response to sulfonylurea	SLCO1B7 OBP2A	1.82e-03	21	89	2	EFO_0004541, EFO_0007922
Disease	ankylosing spondylitis, psoriasis, ulcerative colitis, Crohn's disease, sclerosing cholangitis	NFATC1 PUS10 ETS1 B3GALT6 RAVER1	2.02e-03	295	89	5	EFO_0000384, EFO_0000676, EFO_0000729, EFO_0003898, EFO_0004268
Disease	Intellectual Disability	CACNA1B FOLR1 AGMO LRP2 ALDH4A1 ALG13	2.36e-03	447	89	6	C3714756

Protein segments in the cluster

Peptide	Gene	Start	Entry
FGRYITCNYRATKSV	HTR2B	391	P41595
RFDTEYRSRGCSNQY	B3GALT6	261	Q96L58
PGKRCCQSYDNFSYR	ALG13	681	Q9NP73
GTRVTYFCNDGYRLS	CSMD3	2651	Q7Z407
AQGGLYFRRGQTCYR	CTSZ	21	Q9UBR2
QTFRDYGQSCYAFRK	CCNO	96	P22674
GRNRYCIDKNYAGVL	AGMO	226	Q6ZNB7
RGFKAYYFSGECQEV	CDCP2	246	Q5VXM1
NNGRYCTGKRAIYRS	ADAMTS5	601	Q9UNA0
RYAYRFDFQGLAQAC	FEV	121	Q99581
FEYGGQKCSACSRLY	ALDH4A1	341	P30038
ERYKAFYITGGARAC	ARSG	426	Q96EG1
SSEKQRFYSCDRFGG	CACNA1B	2121	Q00975
ANNCGFSYRQRITYC	ADAMTS20	1601	P59510
RFQYGATSRQCKYGE	ADAMTS6	491	Q9UKP5
SANAKYRYQKRGGFD	BAZ1A	566	Q9NRL2
CFLVYSERTGQSKGY	RAVER1	161	Q8IY67
FDAITKAYYRGAQAC	RAB23	71	Q9ULC3
KAYYRGAQACVLVFS	RAB23	76	Q9ULC3
QERFKCIASTYYRGA	RAB34	111	Q9BZG1
FRYCGRTEVQSVQYG	PTPN4	331	P29074
VDYFKRQGFSYQGRA	NSUN5	151	Q96P11
YVSNFSAAGCRGRLY	KLHL30	411	Q0D2K2
ELANYYFGFNGCSKR	RDM1	116	Q8NG50
ERIARTQGGRYYCKA	MDGA1	96	Q8NFP4
CVGRGFQYYRAKGNV	FBXO22	326	Q8NEZ5
TFSNRGTFRCYGYEN	LILRA4	186	P59901
YGICVNFYRSFQKRI	MADD	91	Q8WXG6
GQYQCSSFARCYNIR	NPNT	221	Q6UXI9
YQCKNYYRLRTEGDG	HPR	51	P00739
NNLRAEGTAVYYCAR	IGHV3-38	101	A0A0C4DH36
QRECVSRQEYRKYGG	IGF1R	876	P08069
AGKRYVYRFVCDLQS	ETS1	406	P14921
DYRNIRISFGTDYGC	EXOSC9	31	Q06265
DANKAGRYQCQYRIG	FCAR	91	P24071
RCFSDFKQRGFVVGY	PGM2L1	101	Q6PCE3
FYVCNGKRKRSQYQR	NFATC1	676	O95644
YTQRIYRANKYDGSG	LRP2	2611	P98164
QPAKGRVYFTYCGQR	HECTD4	2086	Q9Y4D8
GTDDYVFYCKDQRRG	OBP2A	106	Q9NY56
SVGFNGRSQCYYFEN	PANK2	351	Q9BZ23
EKGCNIRTQSYKYRF	PLA2G5	76	P39877
GAVFVAGRYNKYSRN	PUS10	286	Q3MIT2
YGNYTCRAANRLGAS	IGLON5	286	A6NGN9
TCFDKYTGNTYRVGD	FN1	96	P02751
KEGVRASYNYCRQNF	DHX57	1136	Q6P158
KCKNRYSAFNYRATG	GIMAP8	391	Q8ND71
RKLSVACFYGGTSYQ	DDX50	236	Q9BQ39
GVNYYFNVKFGRTTC	CST5	81	P28325
YKVSNYSRGSGRCIQ	FOLR2	191	P14207
RGCGQYISYRCQEKR	LY6G5B	71	Q8NDX9
YRCGYCKNESGSRSN	ATE1	21	O95260
ENGRKYSRYGRCTGH	EML4	706	Q9HC35
RGYDCRSNLFYTQIG	EML5	686	Q05BV3
RGYDCRNNLFYTQAG	EML6	686	Q6ZMW3
RAGRAADGNYYNARK	DGLUCY	436	Q7Z3D6
NRGDFRGYCYVEFKE	SART3	741	Q15020
FGGRRQFCKRSYSDL	PPRC1	1616	Q5VV67
SYKVSNYSRGSGRCI	FOLR1	196	P15328
ESRTGANKYVYFVCN	RSPH4A	421	Q5TD94
ARGNAYSTAKGNVYF	CARS2	181	Q9HA77
TEGQYCQRCKPGFYR	NTN4	366	Q9HB63
YLFQRYGCRVQLGGS	YARS2	231	Q9Y2Z4
YYMGFRQNQKEGRCS	SMN1	276	Q16637
CYRQKKYALAAGQFR	SPATA16	186	Q9BXB7
CRIYNSTYLGRAFFG	SLCO1B7	566	G3V0H7
YGQTVTYSCNRGFRL	SVEP1	2516	Q4LDE5
NGGHYEQRFRYTCKA	SEMA5A	721	Q13591
VVFTRYGKCYTFNSG	ASIC1	186	P78348
HKGKSYRYNRCQRFG	ZBTB25	371	P24278
ARGTRYQTFVNFNYC	TRIM5	331	Q9C035
YACSECGKGFTYNRN	ZNF197	846	O14709
CKNFAELARRGYYNG	PPIL1	36	Q9Y3C6
FIYGGCRGNKNSYRS	SPINT2	161	O43291
GACRIYNSVFFGRVY	SLCO1B3	611	Q9NPD5
CRANENRFYYNSVIG	TFPI	226	P10646
GKYRNRTACTQFIKY	ZNF862	591	O60290
MGGAYRCNYTRKNFR	TRPM1	541	Q7Z4N2
RQGLISAAQYYKSCR	ZNF598	786	Q86UK7
QTRVNFYKCEAYGRA	ZNF117	131	Q03924
RYTQSCRQFLYGGCE	TFPI2	56	P48307
GKGFYTNSQCYSHQR	ZNF224	406	Q9NZL3
RAAYRYFACPQTKGG	TUT4	701	Q5TAX3
GLIKNSRFYNYTVCR	SULF1	161	Q8IWU6
SRFYNYTVCRNGIKE	SULF1	166	Q8IWU6
YYGCNECGTTFNRKS	ZNF605	616	Q86T29
NSRFYNYTLCRNGVK	SULF2	166	Q8IWU5
DACRKAVYYTGNSGA	USP5	671	P45974
GNCVGRRNYRFFYAF	ZDHHC18	226	Q9NUE0
RDIYRSQSFKGGNYA	UBE2Q1	261	Q7Z7E8
YCGYFGQRRLFELSQ	WDR64	901	B1ANS9
FRYLNRGCTRYFANK	MYO6	271	Q9UM54