Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionpotassium:chloride symporter activity

SLC12A4 SLC12A7 SLC12A5

8.39e-089213GO:0015379
GeneOntologyMolecularFunctionsolute:monoatomic cation symporter activity

SLC12A4 SLC13A2 SLC12A7 SLC13A5 SLC12A5

1.30e-07119215GO:0015294
GeneOntologyMolecularFunctionammonium channel activity

SLC12A4 SLC12A7 SLC12A5

2.19e-0712213GO:0008519
GeneOntologyMolecularFunctionsymporter activity

SLC12A4 SLC13A2 SLC12A7 SLC13A5 SLC12A5

4.13e-07150215GO:0015293
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC12A4 SLC44A4 SLC13A2 SLC12A7 SLC13A5 SLC12A5

4.54e-07296216GO:0015291
GeneOntologyMolecularFunctionchloride:monoatomic cation symporter activity

SLC12A4 SLC12A7 SLC12A5

1.75e-0623213GO:0015377
GeneOntologyMolecularFunctionmonoatomic anion:monoatomic cation symporter activity

SLC12A4 SLC12A7 SLC12A5

2.57e-0626213GO:0015296
GeneOntologyMolecularFunctiontransporter activity

SLC12A4 PITPNM1 SLC44A4 SLC13A2 SLC12A7 SLC13A5 ATP8B2 PIEZO2 SLC12A5

2.74e-061289219GO:0005215
GeneOntologyMolecularFunctionsodium:dicarboxylate symporter activity

SLC13A2 SLC13A5

3.16e-063212GO:0017153
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC12A4 SLC44A4 SLC13A2 SLC12A7 SLC13A5 SLC12A5

7.20e-06477216GO:0022804
GeneOntologyMolecularFunctiondolichyl-diphosphooligosaccharide-protein glycotransferase activity

STT3A STT3B

1.05e-055212GO:0004579
GeneOntologyMolecularFunctionoligosaccharyl transferase activity

STT3A STT3B

1.05e-055212GO:0004576
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

SLC12A4 SLC13A2 SLC12A7 SLC13A5 SLC12A5

1.26e-05301215GO:0022853
GeneOntologyMolecularFunctionsuccinate transmembrane transporter activity

SLC13A2 SLC13A5

1.58e-056212GO:0015141
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

SLC12A4 SLC13A2 SLC12A7 SLC13A5 PIEZO2 SLC12A5

4.68e-05664216GO:0008324
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SLC12A4 SLC13A2 SLC12A7 SLC13A5 SLC12A5

1.00e-04465215GO:0046873
GeneOntologyMolecularFunctionC4-dicarboxylate transmembrane transporter activity

SLC13A2 SLC13A5

1.10e-0415212GO:0015556
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

SLC12A4 SLC13A2 SLC12A7 SLC13A5 PIEZO2 SLC12A5

1.25e-04793216GO:0015075
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC12A4 SLC44A4 SLC13A2 SLC12A7 SLC13A5 PIEZO2 SLC12A5

1.38e-041180217GO:0022857
GeneOntologyMolecularFunctionphosphatidylcholine transporter activity

PITPNM1 ATP8B2

1.98e-0420212GO:0008525
GeneOntologyMolecularFunctionchloride transmembrane transporter activity

SLC12A4 SLC12A7 SLC12A5

2.93e-04125213GO:0015108
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

SLC12A4 SLC13A2 SLC12A7 SLC13A5 SLC12A5

4.02e-04627215GO:0022890
GeneOntologyMolecularFunctiondicarboxylic acid transmembrane transporter activity

SLC13A2 SLC13A5

4.81e-0431212GO:0005310
GeneOntologyMolecularFunctionmonoatomic anion transmembrane transporter activity

SLC12A4 SLC12A7 SLC12A5

5.10e-04151213GO:0008509
GeneOntologyMolecularFunctionorganic acid:sodium symporter activity

SLC13A2 SLC13A5

6.14e-0435212GO:0005343
GeneOntologyMolecularFunctionpotassium ion transmembrane transporter activity

SLC12A4 SLC12A7 SLC12A5

6.84e-04167213GO:0015079
GeneOntologyMolecularFunctioninorganic anion transmembrane transporter activity

SLC12A4 SLC12A7 SLC12A5

7.33e-04171213GO:0015103
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

SLC12A4 SLC13A2 SLC12A7 SLC13A5 SLC12A5

9.53e-04758215GO:0015318
GeneOntologyMolecularFunctionchannel activity

SLC12A4 SLC12A7 PIEZO2 SLC12A5

1.98e-03525214GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

SLC12A4 SLC12A7 PIEZO2 SLC12A5

1.99e-03526214GO:0022803
GeneOntologyMolecularFunctionphospholipid transporter activity

PITPNM1 ATP8B2

2.72e-0374212GO:0005548
GeneOntologyMolecularFunctionsolute:sodium symporter activity

SLC13A2 SLC13A5

3.25e-0381212GO:0015370
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLC44A4 SLC13A2 SLC13A5

3.42e-03293213GO:0008514
GeneOntologyMolecularFunctionG protein-coupled peptide receptor activity

GPR182 MCHR2

8.51e-03133212GO:0008528
GeneOntologyMolecularFunctionpeptide receptor activity

GPR182 MCHR2

9.39e-03140212GO:0001653
GeneOntologyMolecularFunctionprotein kinase binding

SLC12A4 PITPNM1 SLC12A7 SLC12A5

1.20e-02873214GO:0019901
GeneOntologyMolecularFunctionG protein-coupled receptor activity

OR1D5 OR1D4 GPR182 MCHR2

1.25e-02884214GO:0004930
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC13A2 SLC13A5

1.38e-02171212GO:0015081
GeneOntologyMolecularFunctionkinase binding

SLC12A4 PITPNM1 SLC12A7 SLC12A5

1.70e-02969214GO:0019900
GeneOntologyMolecularFunctionlipid transporter activity

PITPNM1 ATP8B2

1.78e-02196212GO:0005319
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

SLC13A2 SLC13A5

1.97e-02207212GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

SLC13A2 SLC13A5

1.99e-02208212GO:0005342
GeneOntologyMolecularFunctionhexosyltransferase activity

STT3A STT3B

2.05e-02211212GO:0016758
GeneOntologyMolecularFunctioncalmodulin binding

WFS1 MYO10

2.40e-02230212GO:0005516
GeneOntologyBiologicalProcessammonium transmembrane transport

SLC12A4 SLC12A7 SLC12A5

2.58e-0713213GO:0072488
GeneOntologyBiologicalProcessfumarate transport

SLC13A2 SLC13A5

9.87e-072212GO:0015741
GeneOntologyBiologicalProcesschloride ion homeostasis

SLC12A4 SLC12A7 SLC12A5

2.06e-0625213GO:0055064
GeneOntologyBiologicalProcessmonoatomic anion homeostasis

SLC12A4 SLC12A7 SLC12A5

2.93e-0628213GO:0055081
GeneOntologyBiologicalProcessco-translational protein modification

STT3A STT3B

2.96e-063212GO:0043686
GeneOntologyBiologicalProcessammonium import across plasma membrane

SLC12A4 SLC12A7

5.92e-064212GO:0140157
GeneOntologyBiologicalProcesspotassium ion homeostasis

SLC12A4 SLC12A7 SLC12A5

6.91e-0637213GO:0055075
GeneOntologyBiologicalProcesscell volume homeostasis

SLC12A4 SLC12A7 SLC12A5

1.02e-0542213GO:0006884
GeneOntologyBiologicalProcesssuccinate transmembrane transport

SLC13A2 SLC13A5

1.48e-056212GO:0071422
GeneOntologyBiologicalProcesssuccinate transport

SLC13A2 SLC13A5

1.48e-056212GO:0015744
GeneOntologyBiologicalProcesspotassium ion import across plasma membrane

SLC12A4 SLC12A7 SLC12A5

1.84e-0551213GO:1990573
GeneOntologyBiologicalProcessalpha-ketoglutarate transport

SLC13A2 SLC13A5

2.07e-057212GO:0015742
GeneOntologyBiologicalProcessmonoatomic ion transport

SLC12A4 SLC13A2 SLC12A7 WFS1 SLC13A5 ATP8B2 PIEZO2 SLC12A5

3.53e-051374218GO:0006811
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

SLC12A4 SLC13A2 SLC12A7 SLC13A5 ATP8B2 PIEZO2 SLC12A5

7.88e-051115217GO:0034220
GeneOntologyBiologicalProcessmonoatomic cation transport

SLC12A4 SLC13A2 SLC12A7 WFS1 SLC13A5 PIEZO2 SLC12A5

9.95e-051157217GO:0006812
GeneOntologyBiologicalProcesscellular response to lithium ion

SLC13A2 SLC13A5

1.50e-0418212GO:0071285
GeneOntologyBiologicalProcesschloride transmembrane transport

SLC12A4 SLC12A7 SLC12A5

1.93e-04112213GO:1902476
GeneOntologyBiologicalProcessresponse to lithium ion

SLC13A2 SLC13A5

2.25e-0422212GO:0010226
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

SLC12A4 SLC13A2 SLC12A7 SLC13A5 PIEZO2 SLC12A5

2.68e-04942216GO:0098655
GeneOntologyBiologicalProcessprotein N-linked glycosylation via asparagine

STT3A STT3B

2.69e-0424212GO:0018279
GeneOntologyBiologicalProcesschloride transport

SLC12A4 SLC12A7 SLC12A5

2.86e-04128213GO:0006821
GeneOntologyBiologicalProcessinorganic anion transmembrane transport

SLC12A4 SLC12A7 SLC12A5

3.27e-04134213GO:0098661
GeneOntologyBiologicalProcessmetal ion transport

SLC12A4 SLC13A2 SLC12A7 WFS1 SLC13A5 SLC12A5

3.70e-041000216GO:0030001
GeneOntologyBiologicalProcessinorganic cation import across plasma membrane

SLC12A4 SLC12A7 SLC12A5

3.88e-04142213GO:0098659
GeneOntologyBiologicalProcessinorganic ion import across plasma membrane

SLC12A4 SLC12A7 SLC12A5

3.88e-04142213GO:0099587
GeneOntologyBiologicalProcessC4-dicarboxylate transport

SLC13A2 SLC13A5

3.94e-0429212GO:0015740
GeneOntologyBiologicalProcessmonoatomic anion transmembrane transport

SLC12A4 SLC12A7 SLC12A5

4.83e-04153213GO:0098656
GeneOntologyBiologicalProcessorganophosphate ester transport

PITPNM1 SLC44A4 ATP8B2

5.70e-04162213GO:0015748
GeneOntologyBiologicalProcessinorganic anion transport

SLC12A4 SLC12A7 SLC12A5

7.74e-04180213GO:0015698
GeneOntologyBiologicalProcessmonoatomic anion transport

SLC12A4 SLC12A7 SLC12A5

8.12e-04183213GO:0006820
GeneOntologyBiologicalProcessregulation of cell size

SLC12A4 SLC12A7 SLC12A5

1.47e-03225213GO:0008361
GeneOntologyBiologicalProcessimport across plasma membrane

SLC12A4 SLC12A7 SLC12A5

1.57e-03230213GO:0098739
GeneOntologyBiologicalProcesspotassium ion transmembrane transport

SLC12A4 SLC12A7 SLC12A5

1.61e-03232213GO:0071805
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

SLC12A4 SLC13A2 SLC12A7 SLC13A5 SLC12A5

1.97e-03922215GO:0098662
GeneOntologyBiologicalProcesspotassium ion transport

SLC12A4 SLC12A7 SLC12A5

2.53e-03272213GO:0006813
GeneOntologyBiologicalProcessprotein N-linked glycosylation

STT3A STT3B

2.69e-0376212GO:0006487
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

SLC12A4 SLC13A2 SLC12A7 SLC13A5 SLC12A5

3.03e-031017215GO:0098660
GeneOntologyBiologicalProcessinorganic ion homeostasis

SLC12A4 SLC12A7 WFS1 SLC12A5

3.26e-03622214GO:0098771
GeneOntologyBiologicalProcessmonoatomic cation homeostasis

SLC12A4 SLC12A7 WFS1 SLC12A5

5.09e-03705214GO:0055080
GeneOntologyBiologicalProcessphospholipid transport

PITPNM1 ATP8B2

5.15e-03106212GO:0015914
GeneOntologyBiologicalProcessmonoatomic ion homeostasis

SLC12A4 SLC12A7 WFS1 SLC12A5

5.41e-03717214GO:0050801
GeneOntologyBiologicalProcessdetection of stimulus

PITPNM1 OR1D5 OR1D4 PIEZO2

5.54e-03722214GO:0051606
GeneOntologyBiologicalProcessERAD pathway

WFS1 STT3B

6.45e-03119212GO:0036503
GeneOntologyBiologicalProcessdicarboxylic acid transport

SLC13A2 SLC13A5

6.56e-03120212GO:0006835
GeneOntologyCellularComponentoligosaccharyltransferase complex

STT3A STT3B

9.55e-0514222GO:0008250
DomainKCL_cotranspt

SLC12A4 SLC12A7 SLC12A5

3.57e-094193IPR000076
DomainSLC12A_fam

SLC12A4 SLC12A7 SLC12A5

3.12e-087193IPR004842
DomainSLC12_C

SLC12A4 SLC12A7 SLC12A5

4.98e-088193IPR018491
DomainSLC12

SLC12A4 SLC12A7 SLC12A5

4.98e-088193PF03522
DomainSTT3

STT3A STT3B

9.80e-072192PF02516
DomainOligo_trans_STT3

STT3A STT3B

9.80e-072192IPR003674
DomainAA-permease/SLC12A_dom

SLC12A4 SLC12A7 SLC12A5

1.36e-0622193IPR004841
DomainAA_permease

SLC12A4 SLC12A7 SLC12A5

1.36e-0622193PF00324
DomainNA_SULFATE

SLC13A2 SLC13A5

2.94e-063192PS01271
DomainNa/sul_symport_CS

SLC13A2 SLC13A5

2.94e-063192IPR031312
DomainNa/sul_symport

SLC13A2 SLC13A5

9.79e-065192IPR001898
DomainNa_sulph_symp

SLC13A2 SLC13A5

9.79e-065192PF00939
Domain-

PITPNM1 ATP8B2

1.90e-03641923.40.50.1000
DomainHAD-like_dom

PITPNM1 ATP8B2

2.88e-0379192IPR023214
Domain7tm_1

OR1D5 OR1D4 GPR182 MCHR2

4.29e-03677194PF00001
DomainG_PROTEIN_RECEP_F1_1

OR1D5 OR1D4 GPR182 MCHR2

4.48e-03685194PS00237
DomainG_PROTEIN_RECEP_F1_2

OR1D5 OR1D4 GPR182 MCHR2

4.62e-03691194PS50262
DomainGPCR_Rhodpsn

OR1D5 OR1D4 GPR182 MCHR2

4.64e-03692194IPR000276
DomainGPCR_Rhodpsn_7TM

OR1D5 GPR182 MCHR2

2.90e-02670193IPR017452
PathwayREACTOME_CATION_COUPLED_CHLORIDE_COTRANSPORTERS

SLC12A4 SLC12A7 SLC12A5

6.10e-087183M27339
PathwayREACTOME_CATION_COUPLED_CHLORIDE_COTRANSPORTERS

SLC12A4 SLC12A7 SLC12A5

6.10e-087183MM15081
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC12A4 SLC44A4 SLC13A2 SLC12A7 SLC13A5 SLC12A5

3.41e-07238186MM15076
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC12A4 SLC44A4 SLC13A2 SLC12A7 SLC13A5 SLC12A5

4.44e-07249186M5988
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC12A4 SLC44A4 SLC13A2 SLC12A7 SLC13A5 ATP8B2 SLC12A5

1.19e-05681187MM14985
PathwayREACTOME_SODIUM_COUPLED_SULPHATE_DI_AND_TRI_CARBOXYLATE_TRANSPORTERS

SLC13A2 SLC13A5

1.54e-055182MM15099
PathwayREACTOME_SODIUM_COUPLED_SULPHATE_DI_AND_TRI_CARBOXYLATE_TRANSPORTERS

SLC13A2 SLC13A5

1.54e-055182M27354
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC12A4 SLC44A4 SLC13A2 SLC12A7 SLC13A5 ATP8B2 SLC12A5

1.97e-05736187M27287
PathwayKEGG_MEDICUS_REFERENCE_N_GLYCAN_PRECURSOR_BIOSYNTHESIS_ALG6_TO_OST

STT3A STT3B

8.41e-0511182M47614
PathwayREACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS

SLC44A4 SLC13A2 SLC13A5

1.16e-0476183MM15072
PathwayREACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS

SLC44A4 SLC13A2 SLC13A5

1.56e-0484183M27334
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC12A4 SLC12A7 SLC12A5

3.28e-04108183M823
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC12A4 SLC12A7 SLC12A5

3.37e-04109183MM15074
PathwayKEGG_N_GLYCAN_BIOSYNTHESIS

STT3A STT3B

1.54e-0346182M11079
PathwayWP_NGLYCAN_BIOSYNTHESIS

STT3A STT3B

2.36e-0357182M48051
PathwayWP_10Q22Q23_COPY_NUMBER_VARIATION

SHLD3 SUSD2

2.96e-0364182M48102
PathwayREACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS

PITPNM1 SLC44A4

1.01e-02120182MM14585
PathwayREACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS

PITPNM1 SLC44A4

1.14e-02128182M706
Pubmed

Influence of K-Cl cotransporter activity on activation of volume-sensitive Cl- channels in human osteoblasts.

SLC12A4 SLC12A7 SLC12A5

8.78e-10422312637262
Pubmed

Disruption of KCC2 reveals an essential role of K-Cl cotransport already in early synaptic inhibition.

SLC12A4 SLC12A7 SLC12A5

1.23e-08822311395011
Pubmed

The WNK-regulated SPAK/OSR1 kinases directly phosphorylate and inhibit the K+-Cl- co-transporters.

SLC12A4 SLC12A7 SLC12A5

1.23e-08822324393035
Pubmed

Similar effects of all WNK3 variants on SLC12 cotransporters.

SLC12A4 SLC12A7 SLC12A5

1.23e-08822321613606
Pubmed

Cation-chloride cotransporters and neuronal function.

SLC12A4 SLC12A7 SLC12A5

1.84e-08922319323993
Pubmed

Rare independent mutations in renal salt handling genes contribute to blood pressure variation.

SLC12A4 SLC12A7 SLC12A5

3.36e-072222318391953
Pubmed

Quantitative glycoproteomics reveals new classes of STT3A- and STT3B-dependent N-glycosylation sites.

STT3A STT3B

3.82e-07222231296534
Pubmed

The middle X residue influences cotranslational N-glycosylation consensus site skipping.

STT3A STT3B

3.82e-07222225029371
Pubmed

Proteome and Glycoproteome Analyses Reveal the Protein N-Linked Glycosylation Specificity of STT3A and STT3B.

STT3A STT3B

3.82e-07222236139350
Pubmed

Mammalian STT3A/B oligosaccharyltransferases segregate N-glycosylation at the translocon from lipid-linked oligosaccharide hydrolysis.

STT3A STT3B

3.82e-07222230181269
Pubmed

Differences in the large extracellular loop between the K(+)-Cl(-) cotransporters KCC2 and KCC4.

SLC12A7 SLC12A5

3.82e-07222220516068
Pubmed

Human Na+ -coupled citrate transporter: primary structure, genomic organization, and transport function.

SLC13A2 SLC13A5

3.82e-07222212445824
Pubmed

Molecular, functional, and genomic characterization of human KCC2, the neuronal K-Cl cotransporter.

SLC12A7 SLC12A5

3.82e-07222212106695
Pubmed

Mutations in STT3A and STT3B cause two congenital disorders of glycosylation.

STT3A STT3B

3.82e-07222223842455
Pubmed

STT3-dependent PD-L1 accumulation on cancer stem cells promotes immune evasion.

STT3A STT3B

1.15e-06322229765039
Pubmed

Structure-Based Identification of Inhibitors for the SLC13 Family of Na(+)/Dicarboxylate Cotransporters.

SLC13A2 SLC13A5

1.15e-06322226176240
Pubmed

Molecular physiology of cation-coupled Cl- cotransport: the SLC12 family.

SLC12A4 SLC12A5

1.15e-06322212739168
Pubmed

A dominant negative mutant of the KCC1 K-Cl cotransporter: both N- and C-terminal cytoplasmic domains are required for K-Cl cotransport activity.

SLC12A4 SLC12A7

1.15e-06322211551954
Pubmed

Cotranslational and posttranslational N-glycosylation of polypeptides by distinct mammalian OST isoforms.

STT3A STT3B

1.15e-06322219167329
Pubmed

K-Cl cotransporter gene expression during human and murine erythroid differentiation.

SLC12A4 SLC12A7

1.15e-06322221733850
Pubmed

Insulin-like growth factor 1 stimulates KCl cotransport, which is necessary for invasion and proliferation of cervical cancer and ovarian cancer cells.

SLC12A4 SLC12A7

1.15e-06322215262997
Pubmed

Keratinocyte-associated protein 2 is a bona fide subunit of the mammalian oligosaccharyltransferase.

STT3A STT3B

2.29e-06422222266900
Pubmed

The oligosaccharyltransferase subunits OST48, DAD1 and KCP2 function as ubiquitous and selective modulators of mammalian N-glycosylation.

STT3A STT3B

3.82e-06522222467853
Pubmed

Molecular properties of the SLC13 family of dicarboxylate and sulfate transporters.

SLC13A2 SLC13A5

3.82e-06522216211368
Pubmed

OST4 is a subunit of the mammalian oligosaccharyltransferase required for efficient N-glycosylation.

STT3A STT3B

5.72e-06622223606741
Pubmed

Oligosaccharyltransferase isoforms that contain different catalytic STT3 subunits have distinct enzymatic properties.

STT3A STT3B

5.72e-06622212887896
Pubmed

Behavioural phenotypes of hypomorphic KCC2-deficient mice.

SLC12A4 SLC12A5

8.01e-06722215813942
Pubmed

Cation chloride cotransporters interact with the stress-related kinases Ste20-related proline-alanine-rich kinase (SPAK) and oxidative stress response 1 (OSR1).

SLC12A4 SLC12A7

1.07e-05822212386165
Pubmed

Loss of K-Cl co-transporter KCC3 causes deafness, neurodegeneration and reduced seizure threshold.

SLC12A7 SLC12A5

1.37e-05922214532115
Pubmed

Cryo-electron microscopy structures of human oligosaccharyltransferase complexes OST-A and OST-B.

STT3A STT3B

2.09e-051122231831667
Pubmed

Proteomic analysis of mammalian oligosaccharyltransferase reveals multiple subcomplexes that contain Sec61, TRAP, and two potential new subunits.

STT3A STT3B

2.51e-051222215835887
Pubmed

ZMPSTE24 defends against influenza and other pathogenic viruses.

SLC12A7 STT3B

2.97e-051322228246125
Pubmed

Sequence, structure, and evolution of a complete human olfactory receptor gene cluster.

OR1D5 OR1D4

4.56e-051622210673334
Pubmed

EDEM1 Drives Misfolded Protein Degradation via ERAD and Exploits ER-Phagy as Back-Up Mechanism When ERAD Is Impaired.

WFS1 STT3A STT3B

1.14e-0415022332423001
Pubmed

Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins.

SLC12A4 WFS1 STT3A STT3B

2.49e-0449922422810586
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

SLC12A4 SLC12A7 WFS1 STT3B

2.59e-0450422434432599
Pubmed

ER-export and ARFRP1/AP-1-dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication.

SLC12A4 SLC12A7 WFS1 STT3A STT3B

2.72e-0495222538569033
Pubmed

Congenital Disorders of N-Linked Glycosylation and Multiple Pathway Overview

STT3A STT3B

3.56e-044422220301507
Pubmed

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.

SLC12A4 PITPNM1 SLC12A7 STT3B

4.08e-0456822437774976
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

SLC12A4 SLC12A7 PIEZO2 STT3B

4.10e-0456922430639242
Pubmed

Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.

MYO10 PIEZO2

4.23e-044822223377640
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

SLC12A4 SLC12A7 WFS1 ATP8B2 STT3A

4.47e-04106122533845483
Pubmed

Protein Binder Toolbox for Studies of Solute Carrier Transporters.

SLC12A4 SLC12A7

5.76e-045622238878854
Pubmed

Inhibition of N-glycan processing modulates the network of EDEM3 interactors.

STT3A STT3B

5.97e-045722228366632
InteractionSLC12A5 interactions

SLC12A4 SLC12A7 SLC12A5

1.10e-0621203int:SLC12A5
InteractionSLC12A7 interactions

SLC12A4 SLC12A7 OR1D4 SLC12A5

7.85e-06132204int:SLC12A7
InteractionRXFP1 interactions

SLC12A4 SLC12A7 ATP8B2

9.29e-0590203int:RXFP1
Cytoband7p22.1

RSPH10B2 RSPH10B

2.34e-04472227p22.1
CytobandEnsembl 112 genes in cytogenetic band chr17p13

OR1D5 OR1D4 SLC13A5

5.88e-04346223chr17p13
Cytoband17p13.3

OR1D5 OR1D4

8.18e-048822217p13.3
CytobandEnsembl 112 genes in cytogenetic band chr7p22

RSPH10B2 RSPH10B

1.88e-03134222chr7p22
CytobandEnsembl 112 genes in cytogenetic band chr17q11

SLC13A2 RSKR

3.03e-03171222chr17q11
CytobandEnsembl 112 genes in cytogenetic band chr5p15

SLC12A7 MYO10

4.28e-03204222chr5p15
GeneFamilySolute carriers

SLC12A4 SLC44A4 SLC13A2 SLC12A7 SLC13A5 SLC12A5

6.97e-07395166752
GeneFamilySTT3 oligosaccharyltransferase catalytic subunits|Oligosaccharyltransferase complex subunits

STT3A STT3B

7.34e-072162444
GeneFamilyOligosaccharyltransferase complex subunits

STT3A STT3B

4.82e-0512162445
GeneFamilyOlfactory receptors, family 1

OR1D5 OR1D4

5.62e-0440162147
CoexpressionAtlasDevelopingKidney_e15.5_early proxim tubul_emap-28005_k-means-cluster#5_top-relative-expression-ranked_1000

SLC44A4 SLC13A2 SLC12A7 SUSD2

4.57e-05230194gudmap_developingKidney_e15.5_early proxim tubul_1000_k5
ToppCell10x3'2.3-week_14-16-Endothelial-stroma-sinusoidal_EC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

WFS1 MYO10 GPR182 PIEZO2

2.45e-06197224f1080d93acf1a4756d2f2c8cabd1fb50bc7bcd09
ToppCelldistal-1-Endothelial-Lymphatic|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

WFS1 SLC13A5 GPR182 PIEZO2

2.50e-06198224b6fea363463c8dd7e6780c085ece4900266a6286
ToppCell10x3'2.3-week_14-16-Endothelial|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

WFS1 MYO10 GPR182 PIEZO2

2.55e-0619922441f046646fff65b7e51b63d3204f76ef32054781
ToppCell10x3'2.3-week_14-16-Endothelial-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

WFS1 MYO10 GPR182 PIEZO2

2.55e-06199224ef7f7f7c861827574b120f48cf4052c563929081
ToppCell10x5'v1-week_14-16-Endothelial-stroma-sinusoidal_EC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

WFS1 MYO10 GPR182 PIEZO2

2.60e-06200224ae429f2de652cc1976e63644781197e9ce0e70c8
ToppCell3'-Pediatric_IBD-SmallIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

WFS1 GPR182 PIEZO2

7.74e-051702234848965bc7e9356c6601bb41eeea1553d2eea87e
ToppCellEndothelial-B-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

WFS1 GPR182 PIEZO2

7.88e-0517122307ff7059071da83da1d8f266a586573920d75b58
ToppCelldroplet-Heart-4Chambers-18m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC12A7 MYO10 GPR182

8.15e-051732239a04271c51fae34f547db3206f9ff5857686e45c
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_4|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

SLC44A4 MYO10 SUSD2

8.29e-05174223110369f6b78de34a6d934b5b47cecd023347bc80
ToppCellHealthy_Control-Myeloid-Mast-|Healthy_Control / Condition, Lineage, Cell class and cell subclass

MYO10 ATP8B2 PIEZO2

8.44e-05175223eadbbcdf2aef4cee268bc70a7a2c4175d898953b
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ATP8B2 RSPH10B PIEZO2

8.44e-051752239a96a946db731ba24c9be34bedebf1f4a1372b9e
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ATP8B2 RSPH10B PIEZO2

8.44e-051752232b51406a2c2daa13ab4ed283ede038cd11d9e641
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ATP8B2 RSPH10B PIEZO2

8.44e-0517522354c1f080195ad8392a095e83b56a4b54073d4c0d
ToppCellHealthy_Control-Myeloid-Mast|Healthy_Control / Condition, Lineage, Cell class and cell subclass

MYO10 ATP8B2 PIEZO2

8.44e-05175223ca187074adcc9b8bd0fa270e2ede1564c8e6c6cf
ToppCell3'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

WFS1 RSPH10B PIEZO2

8.58e-051762235d3b2395bb842eea39175f5af6a4c76527e2fc31
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

WFS1 GPR182 PIEZO2

8.87e-05178223ad3de3e03a401dac64431a541899445262246347
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_TIP|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

SLC12A7 GPR182 PIEZO2

8.87e-05178223cda7695411655bd6d0ba69e5041ca7530a9dad3a
ToppCellILEUM-non-inflamed-(7)_Lymphatics|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

WFS1 GPR182 PIEZO2

9.02e-0517922399777a8931356d1206b8ab22aaa1b1d5a600b809
ToppCellCOVID-19-Heart-Lymph_EC|Heart / Disease (COVID-19 only), tissue and cell type

WFS1 GPR182 PIEZO2

9.02e-05179223411620201a860716a8773b92f50f7b94ef34a586
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

WFS1 GPR182 PIEZO2

9.32e-05181223e898ecb8d8f2eb2204225b7b0d665cadcd241139
ToppCelldroplet-Liver-hepatocytes-3m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO10 ATP8B2 GPR182

9.32e-05181223cbb530566893281289026bfd93adf721decd4ca3
ToppCelldroplet-Liver-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO10 ATP8B2 GPR182

9.32e-051812234df7972f88117108698efd06b124b232f8588981
ToppCell5'-Adult-Appendix-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

WFS1 GPR182 PIEZO2

9.47e-05182223fd786c88826ad3d5cc5c3d80f8e392d6be1b5267
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

WFS1 GPR182 PIEZO2

9.63e-051832234d16bfbadf2cd13008c35e23dd2b5b4ecf92ee11
ToppCell(6)_Endothelial-F_(Lymphatics)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

WFS1 GPR182 PIEZO2

9.79e-0518422303ea613e00b45c81b752c14505a0538d698f551e
ToppCell5'-Adult-Appendix-Endothelial-lymphatic_endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

WFS1 GPR182 PIEZO2

9.79e-05184223453295362888c9a59d0e73c7a5b15914c50ff591
ToppCell3'-Child09-12-SmallIntestine-Endothelial-lymphatic_endothelial|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

WFS1 GPR182 PIEZO2

9.94e-0518522318f5d9438c76e37988a7d17aa2a080af6bedbfc4
ToppCell3'-Child09-12-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

WFS1 GPR182 PIEZO2

9.94e-051852239de1db2ce9e44956b1214daf6e1e161334679c88
ToppCellILEUM-inflamed-(7)_Lymphatics|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

WFS1 GPR182 PIEZO2

9.94e-05185223d711dd2e91cfee723dae1ccb2b910b8cf3becc3b
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

WFS1 GPR182 PIEZO2

1.01e-0418622340070d9cd20188ba49b32acfca9bc16256b38bf5
ToppCell343B-Endothelial_cells-Endothelial-F_(Lymphatics)|343B / Donor, Lineage, Cell class and subclass (all cells)

WFS1 GPR182 PIEZO2

1.01e-041862237a8da2ad140bea3207bd868212cc5e201d586772
ToppCell343B-Endothelial_cells-Endothelial-F_(Lymphatics)-|343B / Donor, Lineage, Cell class and subclass (all cells)

WFS1 GPR182 PIEZO2

1.01e-04186223dc394034929c6b10ae0e1c1a028cc3d4ce873298
ToppCell3'-Child04-06-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

WFS1 GPR182 PIEZO2

1.01e-0418622330dd4164c101006c8d95922d89652b82dbe4b5ea
ToppCell(4)_Lymph_vessel|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

WFS1 GPR182 PIEZO2

1.01e-041862236b3afc2ae870ff73e30a60ce84fcee0eb365d809
ToppCell10x5'v1-week_12-13-Endothelial-stroma-sinusoidal_EC|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

WFS1 GPR182 PIEZO2

1.01e-04186223e8ead5634686ebaa6a230eea69795d923ce9939d
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

WFS1 GPR182 PIEZO2

1.01e-0418622320340a5b5cc7f07386498a4ef937d6fbc9e347c4
ToppCell3'-Child04-06-SmallIntestine-Endothelial-lymphatic_endothelial|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

WFS1 GPR182 PIEZO2

1.01e-04186223eeacf59a9e6bf1c9fd59b6b13d35e8abae228cf0
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

WFS1 GPR182 PIEZO2

1.03e-041872234c15c0ed41a55271fc793cb76fee97fa64190369
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

WFS1 GPR182 PIEZO2

1.03e-041872235274f2b302bbf7fed30c480af4f35058d2cf61e0
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

WFS1 GPR182 PIEZO2

1.03e-0418722365d406122dffe18279f14a1ed35ba091730b97be
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

WFS1 GPR182 PIEZO2

1.04e-0418822326915db8863f4115b46a81982e187322e21600fd
ToppCell5'-Adult-Distal_Rectal-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

WFS1 GPR182 PIEZO2

1.04e-04188223524a12f433c7b6f33fad36c0716afa06cd3235e9
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

WFS1 GPR182 PIEZO2

1.04e-041882233f76c0f912f8f023ea425be7f43593b3d7f967e3
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

WFS1 GPR182 PIEZO2

1.04e-0418822361ee7b152745164293d8a44ef91ee2393efbdca5
ToppCell5'-Adult-Distal_Rectal-Endothelial-lymphatic_endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

WFS1 GPR182 PIEZO2

1.04e-04188223d2610b81b3c7f22977b5e2137b1f61410fc4ef16
ToppCellCOVID-19-lung-Lymphatic_EC|lung / Disease (COVID-19 only), tissue and cell type

WFS1 GPR182 PIEZO2

1.06e-04189223c8db9aaf54ea3cc96c4a2f777c3389e0f31f67f3
ToppCellILEUM-non-inflamed-(7)_Endothelial_cell-(7)_Lymphatics|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

WFS1 GPR182 PIEZO2

1.08e-041902239ce301841ce9486701fa28eb2a9929e35d476878
ToppCell3'-Pediatric_IBD-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

WFS1 GPR182 PIEZO2

1.09e-04191223361b123c8289015206d5e706ab2c615d9a724179
ToppCellControl-Plasmablast|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

WFS1 ATP8B2 STT3A

1.09e-041912233df5bbdb29bbcbcb8476fdf126b6d4c1ac67d64b
ToppCell3'-Pediatric_IBD-SmallIntestine-Endothelial-lymphatic_endothelial|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

WFS1 GPR182 PIEZO2

1.09e-04191223011dc22c488369734749e839d65d52fe46b6a1a4
ToppCell368C-Endothelial_cells-Endothelial-F_(Lymphatics)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

WFS1 GPR182 PIEZO2

1.11e-04192223b016e229300c183e14c0e2bba494bf49c7899112
ToppCell367C-Endothelial_cells-Endothelial-F_(Lymphatics)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

WFS1 GPR182 PIEZO2

1.11e-041922235f4f44f15d3a2846981e68296643a4634930a211
ToppCell10x3'2.3-week_14-16-Endothelial-stroma-immature_EC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

WFS1 GPR182 PIEZO2

1.11e-041922235af3b2b38495e925497c48f605d618bbf970965d
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_mature|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

WFS1 GPR182 PIEZO2

1.11e-04192223291df12b4b5ff11fbaa43033692b8f4b5cdf65a1
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_mature-Lymphatic_EC_mature_L.2.5.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

WFS1 GPR182 PIEZO2

1.11e-0419222335ffe7aa9ffab85eac3326651e901c39d0119650
ToppCell368C-Endothelial_cells-Endothelial-F_(Lymphatics)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

WFS1 GPR182 PIEZO2

1.11e-04192223ac96831492c62ad9e1f7d0b764fbdf7d8a189ad9
ToppCellCOVID-19-lung-Lymphatic_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

WFS1 GPR182 PIEZO2

1.11e-04192223cbe57cda44232b183821ac633b60a2668265e616
ToppCell367C-Endothelial_cells-Endothelial-F_(Lymphatics)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

WFS1 GPR182 PIEZO2

1.11e-041922235e709c0714e8eba27e03a6def0544256bedb3ced
ToppCellCOPD-Endothelial-Lymphatic|World / Disease state, Lineage and Cell class

WFS1 GPR182 PIEZO2

1.13e-0419322325bdc557055b5bce6a21f8696b48e991c696b979
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

WFS1 GPR182 PIEZO2

1.13e-04193223040f6bb42aa41d0921371fdda1cc0912c4fe1930
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

WFS1 GPR182 PIEZO2

1.13e-04193223e468287c8b30c56d1de65e8347ade233ba6cf584
ToppCell5'-Adult-SmallIntestine-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

WFS1 GPR182 PIEZO2

1.14e-04194223937ee85ffd50869b60f0f6e91017ab77e8b24c0b
ToppCell(4)_Endothelial_cells-(4)_Lymph_vessel|(4)_Endothelial_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

WFS1 GPR182 PIEZO2

1.14e-041942239735b86d3b2480a0b34d8aab8e7bd609d83c2454
ToppCell(6)_Endothelial_cells-(6)_Endothelial-F_(Lymphatics)|(6)_Endothelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

WFS1 GPR182 PIEZO2

1.14e-041942239441202d6fa2ffbef9277d48ae9bc98876c26ec5
ToppCellcellseq-Endothelial-Endothelial_Lymphatic|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

WFS1 GPR182 PIEZO2

1.16e-04195223d8f01746c8f92532bd1a5c1b0bbb86208d64c3cd
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

WFS1 GPR182 PIEZO2

1.16e-041952238f3b455553215f6e191842a5953a79c606f22c08
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

WFS1 GPR182 PIEZO2

1.16e-041952237e71b1707b34ce47fffadf6f64d9554768221fc6
ToppCelldistal-2-Endothelial-Lymphatic|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

WFS1 GPR182 PIEZO2

1.16e-041952238e0f67a67af3bc0b16f48a621f74540f136383b7
ToppCellcellseq-Endothelial-Endothelial_Lymphatic-LEC|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

WFS1 GPR182 PIEZO2

1.16e-04195223918b68a271a81202778714e10b09c5c724575b73
ToppCellcellseq-Endothelial-Endothelial_Lymphatic-LEC-LEC|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

WFS1 GPR182 PIEZO2

1.16e-041952238321531bb976e5005973b82f32177be88113abb3
ToppCell10x5'v1-week_17-19-Endothelial-stroma-sinusoidal_EC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

MYO10 GPR182 PIEZO2

1.16e-0419522322a481927147ec4ae9d59e6af7c87df0e9cb51e4
ToppCell343B-Endothelial_cells-Endothelial-F_(Lymphatics)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

WFS1 GPR182 PIEZO2

1.16e-04195223fc75f04eb475c8139cc5c35e6be22e73fb2be9e6
ToppCell343B-Endothelial_cells-Endothelial-F_(Lymphatics)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

WFS1 GPR182 PIEZO2

1.16e-0419522383d45ff5e5bc704448431149fffb2e4c1278f279
ToppCelldistal-Endothelial-Lymphatic-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

WFS1 GPR182 PIEZO2

1.16e-04195223f45c1349932ee7eb419cced8a4fdedae3610953f
ToppCelldistal-Endothelial-Lymphatic|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

WFS1 GPR182 PIEZO2

1.18e-041962233e8a20e1d163dcbd3bbd99fe179d54af02298af0
ToppCell356C-Endothelial_cells-Endothelial-F_(Lymphatics)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

WFS1 GPR182 PIEZO2

1.18e-04196223b04ca69b0ed44e09c989b575f747e1e819cd8008
ToppCell356C-Endothelial_cells-Endothelial-F_(Lymphatics)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

WFS1 GPR182 PIEZO2

1.18e-04196223a31e227de2dc077b81881295b012d22fedbd65ed
ToppCellEndothelial_cells-Endothelial-B|Endothelial_cells / lung cells shred on cell class, cell subclass, sample id

WFS1 GPR182 PIEZO2

1.18e-0419622336f95f9ef74eb951e41ef46fd136ceaef45208fc
ToppCelldistal-Endothelial-Lymphatic-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

WFS1 SLC13A5 GPR182

1.18e-04196223b0f23dc802a2c2a56a08d398a464ea78b58ade4c
ToppCell390C-Endothelial_cells-Endothelial-F_(Lymphatics)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

WFS1 GPR182 PIEZO2

1.20e-04197223c84e988c2ad06087aafda9e3b68e9e72fd0e75f1
ToppCellnormal_Lung-Endothelial_cells-Lymphatic_ECs|Endothelial_cells / Location, Cell class and cell subclass

WFS1 GPR182 PIEZO2

1.20e-04197223c838d0f64e3b43a616a9e381b8139bfe9aa32da7
ToppCell10x3'2.3-week_17-19-Endothelial-stroma-sinusoidal_EC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

WFS1 GPR182 PIEZO2

1.20e-041972234e58bbf3ecb30b4c8199adcc04d2eb134d90de56
ToppCell390C-Endothelial_cells-Endothelial-F_(Lymphatics)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

WFS1 GPR182 PIEZO2

1.20e-041972236195f945b3fd6da07907619267d49e96d1044f8f
ToppCelltumor_Lung-Endothelial_cells-Lymphatic_ECs|Endothelial_cells / Location, Cell class and cell subclass

WFS1 GPR182 PIEZO2

1.20e-04197223a05237ee6d31d9eab491dd7007859d6285cf1424
ToppCell5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

WFS1 GPR182 PIEZO2

1.22e-041982235d42f4fda2081ea3e9f62a00e7eea702e0d0be7d
ToppCellTransplant_Alveoli_and_parenchyma-Endothelial-Lymphatic|Endothelial / Tissue, Lineage and Cell class of Lung Cells from 10X

WFS1 GPR182 PIEZO2

1.22e-041982237a99c341736a4a2ac48ef8e2f7951f21a7378946
ToppCellmedial-Endothelial-Lymphatic-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

WFS1 GPR182 PIEZO2

1.22e-0419822341983d405215b974044e2e9e6c212b134336a6fe
ToppCell5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

WFS1 GPR182 PIEZO2

1.22e-0419822399d6a64f3410dae3019161feef20a8f06081a24b
ToppCellmedial-2-Endothelial-Lymphatic|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

WFS1 GPR182 PIEZO2

1.22e-04198223e4274584512a72270087a1ab104fab449a2f83bc
ToppCellTracheal-10x5prime-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

WFS1 GPR182 PIEZO2

1.22e-04198223306e28d31fd587409a12dcccc6b2abd7dc9c2e0a
ToppCellmedial-Endothelial-Lymphatic|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

WFS1 GPR182 PIEZO2

1.22e-041982231760fede363544bc0fa2e22fe36aff522abd2525
ToppCellTracheal-10x5prime-Endothelial-Endothelia_lymphatic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

WFS1 GPR182 PIEZO2

1.22e-0419822305429f18e1d74880c1835568c86177f661b3477a
ToppCellParenchymal-10x5prime-Endothelial-Endothelia_lymphatic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

WFS1 GPR182 PIEZO2

1.23e-041992231587d24b19f5bb64a3b6cc1df87c7c472cf41672
ToppCellParenchymal-10x5prime-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

WFS1 GPR182 PIEZO2

1.23e-04199223a9c2041e54899cb8ccc026758647f3ae3ca457dd
ToppCellParenchymal-10x3prime_v2-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

WFS1 GPR182 PIEZO2

1.25e-04200223e3e80cb16e0d2e24efc16b62316a6da91bf81ea5
ToppCellParenchymal-10x3prime_v2-Endothelial-Endothelia_lymphatic|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

WFS1 GPR182 PIEZO2

1.25e-0420022376e90231aa94afc12e618da8ae314c51644acab4
ToppCell10x5'v1-week_14-16-Endothelial|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

WFS1 GPR182 PIEZO2

1.25e-04200223e786544cf6f891550c4be55ebb4928c92297b504
ToppCell10x5'v1-week_14-16-Endothelial-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

WFS1 GPR182 PIEZO2

1.25e-042002232488aa12970a43a5af352e2c36c73884d73a1cc5
ToppCellCOVID_vent|World / Disease condition, Lineage, Cell class and subclass

ATP8B2 STT3A STT3B

1.25e-042002231d88e5cc4534073f27a7562e1c4b884bd67f09d9
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_ALM_Nxph2_Sla|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SLC12A4 SUSD2

1.03e-03972220d68bf2dfb9c221375b70b055f735536afb18f65
ComputationalNeighborhood of RAGE

SLC12A4 PITPNM1 SLC13A2

2.02e-0414893MORF_RAGE
ComputationalNeighborhood of FDXR

SLC12A4 PITPNM1 SLC13A2

7.02e-0422693MORF_FDXR
ComputationalNeighborhood of PTPN9

SLC12A4 PITPNM1

1.11e-036192MORF_PTPN9
ComputationalNeighborhood of ORC1L

SLC12A4 PITPNM1

1.42e-036992MORF_ORC1L
ComputationalNeighborhood of RBM8A

SLC12A4 PITPNM1

2.15e-038592MORF_RBM8A
ComputationalNeighborhood of JAK3

SLC12A4 SLC13A2

2.73e-039692MORF_JAK3
ComputationalNeighborhood of CASP2

SLC12A4 PITPNM1

3.13e-0310392MORF_CASP2
ComputationalNeighborhood of CNTN1

SLC12A4 PITPNM1

3.44e-0310892MORF_CNTN1
DrugPotassium Chloride

SLC12A4 SLC12A7 SLC12A5

1.35e-086213DB00761
Drug((2-n-butyl-6,7-dichloro-2-cyclopentyl-2,3-dihydro-1-oxo-1H-inden-5-yl)oxy)acetic acid

SLC12A4 SLC12A7

8.10e-072212ctd:C095651
Drugbumetanide

SLC12A4 SLC13A2 SLC12A7 SLC13A5 SLC12A5

1.12e-06209215CID000002471
DrugBumetanide

SLC12A4 SLC12A5

8.09e-065212DB00887
DrugTrichlormethiazide

SLC12A4 SLC12A7

8.09e-065212ctd:D014237
DrugDCPIB

SLC12A4 SLC12A5

4.43e-0511212CID010071166
DrugNSC9969

SLC12A4 STT3A

5.32e-0512212CID000095441
DrugBumetanide

SLC12A4 SLC12A7

9.65e-0516212ctd:D002034
Drugfurosemide

SLC12A4 SLC13A2 SLC12A7 SLC12A5

1.02e-04272214CID000003440
Drugnalidixic acid

SLC12A4 GPR182 STT3B SLC12A5

1.09e-04277214CID000004421
DrugL-2-amino-6-oxopimelate

STT3A STT3B

1.09e-0417212CID000194695
DrugHCEC

SLC12A4 GPR182 SLC12A5

1.73e-04119213CID000194176
Diseaseepilepsy (implicated_via_orthology)

SLC12A4 SLC13A2 SLC12A7 SLC13A5 SLC12A5

9.16e-08163215DOID:1826 (implicated_via_orthology)
Diseasecongenital disorder of glycosylation Iw (implicated_via_orthology)

STT3A STT3B

4.82e-072212DOID:0080572 (implicated_via_orthology)
DiseaseKohlschutter-Tonz syndrome (implicated_via_orthology)

SLC13A2 SLC13A5

4.82e-065212DOID:0111668 (implicated_via_orthology)
Diseasealcohol-related neurodevelopmental disorder (implicated_via_orthology)

SLC13A2 SLC13A5

1.35e-058212DOID:0050667 (implicated_via_orthology)
Diseaseclopidogrel metabolite measurement

SLC13A2 RSKR

2.51e-0433212EFO_0007966
Diseaseglomerular filtration rate, renal transplant outcome measurement

OR1D5 OR1D4

2.83e-0435212EFO_0005199, EFO_0005208
DiseaseDevelopmental delay (disorder)

STT3A STT3B

3.16e-0437212C0424605
Diseasemetabolite measurement, diet measurement

SLC44A4 SLC13A5

1.16e-0371212EFO_0004725, EFO_0008111
Diseaseperceived unattractiveness to mosquitos measurement

SLC44A4 GPR182

1.20e-0372212EFO_0008380
DiseaseGlobal developmental delay

STT3A STT3B

4.00e-03133212C0557874
DiseaseMood Disorders

WFS1 SLC12A5

6.30e-03168212C0525045
Diseaseempathy measurement

OR1D5 OR1D4

6.45e-03170212EFO_0009183

Protein segments in the cluster

PeptideGeneStartEntry
RWSYLRMCKFLCYFF

ATP8B2

881

P98198
SYMNKCWEIYLAYCR

RSPH10B

551

P0C881
SYMNKCWEIYLAYCR

RSPH10B2

551

B2RC85
LAMALYACCFEWVIK

MYO10

401

Q9HD67
FIMCSYCSTDLYSLW

RSKR

181

Q96LW2
CYILILCYTWEMYQQ

MCHR2

216

Q969V1
LICIAYWAMTALYLA

SLC44A4

366

Q53GD3
CLALMFICSWYYALS

SLC12A7

626

Q9Y666
FICSWYYALSAMLIA

SLC12A7

631

Q9Y666
AYCAYAIILMALFWC

SLC13A2

36

Q13183
VRCAYVIILMAIYWC

SLC13A5

36

Q86YT5
MSLCLALMFICSWYY

SLC12A5

626

Q9H2X9
ALMFICSWYYALVAM

SLC12A5

631

Q9H2X9
YLFCDMYILLWLACS

OR1D4

176

P47884
YLFCDMYILLWLACS

OR1D5

176

P58170
MSHWLYDVLSFYYCC

SUSD2

406

Q9UGT4
CAYVAVFVMCWLPYH

GPR182

261

O15218
SICWAAKCALAYFYM

STT3A

191

P46977
IWVFCDIMYCEYVGS

SHLD3

211

Q6ZNX1
CLALMFVSSWYYALV

SLC12A4

626

Q9UP95
LMCAYKLCKVEFRYW

PITPNM1

186

O00562
VFWTMCCCLSYFYMV

STT3B

246

Q8TCJ2
FYAMIHACWLIAVLY

PIEZO2

1141

Q9H5I5
GTYCYLVPYLVCFMW

WFS1

526

O76024