Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionG protein-coupled receptor activity

FZD1 FZD4 OR8A1 OR10J5 OR8B4 OR12D2 FZD5 OR1Q1 APLNR FSHR OR2Y1 P2RY13 OR1A2 OR5H2 OR4B1 GRM2 OR4A4P

4.43e-098846817GO:0004930
GeneOntologyMolecularFunctionolfactory receptor activity

OR8A1 OR10J5 OR8B4 OR12D2 OR1Q1 OR2Y1 OR1A2 OR5H2 OR4B1 OR4A4P

1.88e-064316810GO:0004984
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

FZD1 FZD4 OR8A1 OR10J5 OR8B4 OR12D2 FZD5 OR1Q1 APLNR FSHR OR2Y1 P2RY13 OR1A2 OR5H2 OR4B1 GRM2 OR4A4P

1.99e-0613536817GO:0004888
GeneOntologyMolecularFunctionWnt-protein binding

FZD1 FZD4 SFRP4 FZD5

5.28e-0634684GO:0017147
GeneOntologyMolecularFunctiondCMP deaminase activity

CDADC1 DCTD

1.14e-052682GO:0004132
GeneOntologyMolecularFunctionWnt receptor activity

FZD1 FZD4 FZD5

2.48e-0517683GO:0042813
GeneOntologyMolecularFunctionsodium,bicarbonate:chloride antiporter activity

SLC4A8 SLC4A10

3.42e-053682GO:0140892
GeneOntologyMolecularFunctionmonoatomic anion transmembrane transporter activity

ANO4 LRRC8C ANO2 SLC4A8 SLC4A10

1.64e-04151685GO:0008509
GeneOntologyMolecularFunctionsodium:bicarbonate symporter activity

SLC4A8 SLC4A10

1.70e-046682GO:0008510
GeneOntologyMolecularFunctionalkaline phosphatase activity

ALPI ALPG

1.70e-046682GO:0004035
GeneOntologyMolecularFunctionprotein dimerization activity

ANO4 FZD1 FZD4 ANO2 FUT9 CDADC1 PADI2 NOS2 ZHX1 ALPI MAP3K5 ALPG

6.93e-0412056812GO:0046983
GeneOntologyMolecularFunctionchloride:bicarbonate antiporter activity

SLC4A8 SLC4A10

8.70e-0413682GO:0140900
GeneOntologyMolecularFunctionbicarbonate:monoatomic anion antiporter activity

SLC4A8 SLC4A10

8.70e-0413682GO:0140829
GeneOntologyMolecularFunctionmonoatomic cation:bicarbonate symporter activity

SLC4A8 SLC4A10

8.70e-0413682GO:0140410
GeneOntologyMolecularFunctionchloride transmembrane transporter activity

ANO4 ANO2 SLC4A8 SLC4A10

8.75e-04125684GO:0015108
GeneOntologyMolecularFunctionodorant binding

OR8A1 OR8B4 OR12D2 OR5H2

9.28e-04127684GO:0005549
GeneOntologyMolecularFunctionprotein homodimerization activity

FZD1 FZD4 FUT9 CDADC1 PADI2 NOS2 ALPI MAP3K5 ALPG

1.71e-03815689GO:0042803
GeneOntologyMolecularFunctionintracellularly calcium-gated channel activity

ANO4 ANO2

2.09e-0320682GO:0141147
GeneOntologyMolecularFunctionintracellularly calcium-gated chloride channel activity

ANO4 ANO2

2.09e-0320682GO:0005229
GeneOntologyMolecularFunctionimportin-alpha family protein binding

CDADC1 DHX9

2.30e-0321682GO:0061676
GeneOntologyMolecularFunctionphospholipid scramblase activity

ANO4 ANO2

2.76e-0323682GO:0017128
GeneOntologyMolecularFunctioninorganic anion transmembrane transporter activity

ANO4 ANO2 SLC4A8 SLC4A10

2.76e-03171684GO:0015103
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

FZD1 FZD4 OR8A1 OR10J5 GRK3 OR8B4 OR12D2 FZD5 OR1Q1 APLNR FSHR OR2Y1 P2RY13 OR1A2 OR5H2 OR4B1 RGS21 GRM2 PADI2 NOS2 OR4A4P

2.03e-0913956821GO:0007186
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception of smell

OR8A1 OR10J5 OR8B4 OR12D2 OR1Q1 OR2Y1 OR1A2 OR5H2 OR4B1 OR4A4P

1.44e-064326810GO:0050911
GeneOntologyBiologicalProcesssensory perception of chemical stimulus

OR8A1 OR10J5 OR8B4 OR12D2 OR1Q1 OR2Y1 OR1A2 OR5H2 OR4B1 RGS21 OR4A4P

1.61e-065476811GO:0007606
GeneOntologyBiologicalProcesssensory perception of smell

OR8A1 OR10J5 OR8B4 OR12D2 OR1Q1 OR2Y1 OR1A2 OR5H2 OR4B1 OR4A4P

2.78e-064656810GO:0007608
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception

OR8A1 OR10J5 OR8B4 OR12D2 OR1Q1 OR2Y1 OR1A2 OR5H2 OR4B1 OR4A4P

4.04e-064856810GO:0050907
GeneOntologyBiologicalProcessdetection of chemical stimulus

OR8A1 OR10J5 OR8B4 OR12D2 OR1Q1 OR2Y1 OR1A2 OR5H2 OR4B1 OR4A4P

7.97e-065246810GO:0009593
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception

OR8A1 OR10J5 OR8B4 OR12D2 OR1Q1 OR2Y1 OR1A2 OR5H2 OR4B1 OR4A4P

1.98e-055826810GO:0050906
GeneOntologyBiologicalProcesssensory perception

FZD4 OR8A1 OR10J5 OR8B4 OR12D2 OR1Q1 OR2Y1 SLC4A10 OR1A2 OR5H2 OR4B1 RGS21 OR4A4P

4.09e-0510726813GO:0007600
GeneOntologyBiologicalProcessregulation of cyclase activity

FSHR P2RY13 GRM2 NOS2

7.95e-0569684GO:0031279
GeneOntologyBiologicalProcessregulation of lyase activity

FSHR P2RY13 GRM2 NOS2

9.91e-0573684GO:0051339
GeneOntologyBiologicalProcessdetection of stimulus

OR8A1 OR10J5 OR8B4 OR12D2 OR1Q1 OR2Y1 OR1A2 OR5H2 OR4B1 OR4A4P

1.20e-047226810GO:0051606
GeneOntologyBiologicalProcessnon-canonical Wnt signaling pathway

FZD1 FZD4 SFRP4 FZD5

1.22e-0477684GO:0035567
GeneOntologyBiologicalProcessmonoatomic anion transmembrane transport

ANO4 LRRC8C ANO2 SLC4A8 SLC4A10

1.50e-04153685GO:0098656
GeneOntologyBiologicalProcessinorganic anion transport

ANO4 ANO2 SFRP4 SLC4A8 SLC4A10

3.20e-04180685GO:0015698
GeneOntologyBiologicalProcessmonoatomic anion transport

ANO4 LRRC8C ANO2 SLC4A8 SLC4A10

3.45e-04183685GO:0006820
GeneOntologyBiologicalProcesscoenzyme A catabolic process

ALPI ALPG

3.80e-049682GO:0015938
MousePhenolong gestation period

FSHR ALPI ALPG

1.58e-0515473MP:0002293
MousePhenoabnormal gestational length

FSHR ALPI ALPG

2.81e-0518473MP:0002292
MousePhenodecreased susceptibility to osteoporosis

SFRP4 LRRK1

1.10e-045472MP:0012072
MousePhenoabnormal susceptibility to osteoporosis

SFRP4 LRRK1

1.10e-045472MP:0012070
DomainFrizzled/SFRP

FZD1 FZD4 SFRP4 FZD5

2.51e-0716664IPR015526
DomainFRI

FZD1 FZD4 SFRP4 FZD5

6.60e-0720664SM00063
Domain-

FZD1 FZD4 SFRP4 FZD5

8.13e-07216641.10.2000.10
DomainFrizzled_dom

FZD1 FZD4 SFRP4 FZD5

1.43e-0624664IPR020067
DomainFZ

FZD1 FZD4 SFRP4 FZD5

1.43e-0624664PS50038
DomainFz

FZD1 FZD4 SFRP4 FZD5

1.43e-0624664PF01392
DomainGPCR_Rhodpsn_7TM

OR8A1 OR10J5 OR8B4 OR12D2 OR1Q1 APLNR FSHR OR2Y1 P2RY13 OR1A2 OR5H2 OR4B1

3.43e-066706612IPR017452
Domain7tm_1

OR8A1 OR10J5 OR8B4 OR12D2 OR1Q1 APLNR FSHR OR2Y1 P2RY13 OR1A2 OR5H2 OR4B1

3.82e-066776612PF00001
DomainG_PROTEIN_RECEP_F1_1

OR8A1 OR10J5 OR8B4 OR12D2 OR1Q1 APLNR FSHR OR2Y1 P2RY13 OR1A2 OR5H2 OR4B1

4.31e-066856612PS00237
DomainG_PROTEIN_RECEP_F1_2

OR8A1 OR10J5 OR8B4 OR12D2 OR1Q1 APLNR FSHR OR2Y1 P2RY13 OR1A2 OR5H2 OR4B1

4.71e-066916612PS50262
DomainGPCR_Rhodpsn

OR8A1 OR10J5 OR8B4 OR12D2 OR1Q1 APLNR FSHR OR2Y1 P2RY13 OR1A2 OR5H2 OR4B1

4.78e-066926612IPR000276
DomainFrizzled

FZD1 FZD4 FZD5

6.82e-0611663IPR000539
DomainFrizzled

FZD1 FZD4 FZD5

6.82e-0611663PF01534
DomainFrizzled

FZD1 FZD4 FZD5

6.82e-0611663SM01330
DomainOlfact_rcpt

OR8A1 OR10J5 OR8B4 OR12D2 OR1Q1 OR2Y1 OR1A2 OR5H2 OR4B1

9.47e-06393669IPR000725
DomaindCMP_deaminase-rel

CDADC1 DCTD

1.23e-052662IPR015517
DomainAlk_phosphatase

ALPI ALPG

7.35e-054662PF00245
DomainAlkaline_phosphatase_AS

ALPI ALPG

7.35e-054662IPR018299
DomainAlkaline_phosphatase

ALPI ALPG

7.35e-054662IPR001952
DomainalkPPc

ALPI ALPG

7.35e-054662SM00098
DomainALKALINE_PHOSPHATASE

ALPI ALPG

7.35e-054662PS00123
DomainNa/HCO3_transpt

SLC4A8 SLC4A10

1.22e-045662IPR003024
DomaindCMP_cyt_deam_1

CDADC1 DCTD

1.22e-045662PF00383
DomainAnoct_dimer

ANO4 ANO2

2.55e-047662PF16178
DomainANION_EXCHANGER_2

SLC4A8 SLC4A10

2.55e-047662PS00220
DomainAnoct_dimer

ANO4 ANO2

2.55e-047662IPR032394
DomainANION_EXCHANGER_1

SLC4A8 SLC4A10

2.55e-047662PS00219
DomainBand3_cytoplasmic_dom

SLC4A8 SLC4A10

4.36e-049662IPR013769
DomainBand_3_cyto

SLC4A8 SLC4A10

4.36e-049662PF07565
Domain-

SLC4A8 SLC4A10

4.36e-0496623.40.1100.10
DomainHCO3_cotransp

SLC4A8 SLC4A10

5.43e-0410662PF00955
DomainHCO3_transpt_C

SLC4A8 SLC4A10

5.43e-0410662IPR011531
DomainLRR_5

LRRC8C FSHR

5.43e-0410662PF13306
DomainLRR_5

LRRC8C FSHR

5.43e-0410662IPR026906
DomainPTrfase/Anion_transptr

SLC4A8 SLC4A10

5.43e-0410662IPR016152
DomainAnoctamin

ANO4 ANO2

5.43e-0410662PF04547
DomainAnoctamin

ANO4 ANO2

5.43e-0410662IPR007632
DomainHCO3_transpt_euk

SLC4A8 SLC4A10

5.43e-0410662IPR003020
DomainAPOBEC/CMP_deaminase_Zn-bd

CDADC1 DCTD

1.09e-0314662IPR016192
DomainGPCR_2-like

FZD1 FZD4 FZD5

1.25e-0360663IPR017981
DomainCYT_DCMP_DEAMINASES_2

CDADC1 DCTD

1.25e-0315662PS51747
DomainG_PROTEIN_RECEP_F2_4

FZD1 FZD4 FZD5

1.31e-0361663PS50261
DomainCytidine_deaminase-like

CDADC1 DCTD

1.62e-0317662IPR016193
DomainCYT_DCMP_DEAMINASES_1

CDADC1 DCTD

1.62e-0317662PS00903
DomainCMP_dCMP_Zn-bd

CDADC1 DCTD

1.62e-0317662IPR002125
DomainAlkaline_phosphatase_core

ALPI ALPG

5.35e-0331662IPR017850
DomainAlkaline_Pase-like_a/b/a

ALPI ALPG

5.35e-0331662IPR017849
Domain-

ALPI ALPG

5.35e-03316623.40.720.10
DomainZINC_FINGER_C2H2_2

ZFHX4 ZNF177 ZNF217 ZNF772 ZHX1 ZNF595 ZNF292 ZNF646

5.81e-03775668PS50157
DomainZINC_FINGER_C2H2_1

ZFHX4 ZNF177 ZNF217 ZNF772 ZHX1 ZNF595 ZNF292 ZNF646

5.90e-03777668PS00028
DomainRGS

GRK3 RGS21

6.79e-0335662PF00615
DomainRGS

GRK3 RGS21

6.79e-0335662SM00315
DomainRGS

GRK3 RGS21

7.17e-0336662PS50132
DomainZnf_C2H2

ZFHX4 ZNF177 ZNF217 ZNF772 ZHX1 ZNF595 ZNF292 ZNF646

7.25e-03805668IPR007087
DomainZnF_C2H2

ZFHX4 ZNF177 ZNF217 ZNF772 ZHX1 ZNF595 ZNF292 ZNF646

7.41e-03808668SM00355
DomainLRR_1

LRRC8C LRFN2 FSHR LRRK1

7.52e-03219664PF00560
DomainRGS

GRK3 RGS21

8.38e-0339662IPR016137
DomainBTB-kelch_protein

KLHL3 KBTBD2

1.01e-0243662IPR017096
PathwayKEGG_OLFACTORY_TRANSDUCTION

OR8A1 OR10J5 GRK3 OR8B4 OR12D2 OR1Q1 OR2Y1 OR1A2 OR5H2 OR4B1

1.28e-063895210M14091
PathwayREACTOME_OLFACTORY_SIGNALING_PATHWAY

OR8A1 ANO2 OR10J5 OR8B4 OR12D2 OR1Q1 OR2Y1 OR1A2 OR5H2 OR4B1

2.40e-064175210M4072
PathwayWP_POLYCYSTIC_KIDNEY_DISEASE_PATHWAY

FZD1 FZD4 SFRP4 FZD5 WNT8B

1.47e-0585525M48315
PathwayKEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_SOST_LRP4

FZD1 FZD4 FZD5

1.67e-0514523M47834
PathwayWNT_SIGNALING

FZD1 FZD4 SFRP4 FZD5 CCND2

1.84e-0589525M5493
PathwayKEGG_WNT_SIGNALING_PATHWAY

FZD1 FZD4 SFRP4 FZD5 WNT8B CCND2

1.85e-05151526M19428
PathwayKEGG_MEDICUS_VARIANT_LRP6_OVEREXPRESSION_TO_WNT_SIGNALING_PATHWAY

FZD1 FZD4 FZD5 WNT8B

2.19e-0545524M47412
PathwayKEGG_MEDICUS_REFERENCE_WNT_SIGNALING_PATHWAY

FZD1 FZD4 FZD5 WNT8B

2.40e-0546524M47409
PathwayKEGG_MEDICUS_REFERENCE_WNT5A_ROR_SIGNALING_PATHWAY

FZD1 FZD4 FZD5

2.56e-0516523M47823
PathwayWP_GPCRS_OTHER

FZD1 FZD5 OR2Y1 OR1A2 OR4B1

2.66e-0596525MM15939
PathwayKEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_LGR_RSPO

FZD1 FZD4 FZD5

4.40e-0519523M47833
PathwayKEGG_BASAL_CELL_CARCINOMA

FZD1 FZD4 FZD5 WNT8B

4.89e-0555524M17807
PathwayWP_GPCRS_NONODORANT

FZD1 FZD4 FZD5 APLNR FSHR P2RY13 GRM2

5.10e-05266527MM15843
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

OR8A1 OR10J5 OR8B4 APLNR FSHR P2RY13

5.99e-05186526MM15994
PathwayWP_WNT_SIGNALING

FZD1 SFRP4 FZD5 CCND2

7.35e-0561524MM15893
PathwayREACTOME_SENSORY_PERCEPTION

OR8A1 ANO2 OR10J5 OR8B4 OR12D2 OR1Q1 OR2Y1 OR1A2 OR5H2 OR4B1

9.24e-056365210M41834
PathwayPID_WNT_SIGNALING_PATHWAY

FZD1 FZD4 FZD5

1.45e-0428523M77
PathwayREACTOME_DISASSEMBLY_OF_THE_DESTRUCTION_COMPLEX_AND_RECRUITMENT_OF_AXIN_TO_THE_MEMBRANE

FZD1 FZD5 WNT8B

1.98e-0431523M27400
PathwayREACTOME_DISASSEMBLY_OF_THE_DESTRUCTION_COMPLEX_AND_RECRUITMENT_OF_AXIN_TO_THE_MEMBRANE

FZD1 FZD5 WNT8B

1.98e-0431523MM15154
PathwayBIOCARTA_WNT_LRP6_PATHWAY

FZD1 WNT8B

1.98e-046522MM1588
PathwayBIOCARTA_WNT_LRP6_PATHWAY

FZD1 WNT8B

1.98e-046522M22083
PathwayREACTOME_SIGNALING_BY_GPCR

FZD1 FZD4 GRK3 FZD5 WNT8B APLNR FSHR P2RY13 RGS21 GRM2

2.08e-047025210M746
PathwayREACTOME_GPCR_LIGAND_BINDING

FZD1 FZD4 FZD5 WNT8B APLNR FSHR P2RY13 GRM2

2.69e-04463528M507
PathwayWP_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_IN_COLORECTAL_CANCER

FZD1 FZD4 COL4A2 FZD5 WNT8B

3.08e-04161525M39770
PathwayWP_WNT_SIGNALING_IN_KIDNEY_DISEASE

FZD1 FZD4 FZD5

3.10e-0436523M39699
PathwayWP_NCRNAS_INVOLVED_IN_WNT_SIGNALING_IN_HEPATOCELLULAR_CARCINOMA

FZD1 SFRP4 FZD5 CCND2

3.19e-0489524M39563
PathwayREACTOME_SIGNALING_BY_RNF43_MUTANTS

FZD4 FZD5

3.68e-048522M27433
PathwayWP_ALZHEIMERS_DISEASE

FZD1 SFRP4 FZD5 NOS2 RYR3 MAP3K5

3.79e-04261526M42565
PathwayREACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS

FZD1 FZD4 FZD5 WNT8B

3.93e-0494524M797
PathwayWP_LNCRNA_IN_CANONICAL_WNT_SIGNALING_AND_COLORECTAL_CANCER

FZD1 SFRP4 FZD5 CCND2

4.60e-0498524M39731
PathwayKEGG_MELANOGENESIS

FZD1 FZD4 FZD5 WNT8B

5.16e-04101524M7761
PathwayWP_WNT_SIGNALING_PATHWAY_AND_PLURIPOTENCY

FZD1 FZD4 FZD5 CCND2

5.16e-04101524MM15829
PathwayWP_WNT_SIGNALING_AND_PLURIPOTENCY

FZD1 FZD4 FZD5 CCND2

5.16e-04101524M39387
PathwayWP_WNT_SIGNALING_IN_KIDNEY_DISEASE

FZD1 FZD4 FZD5

5.64e-0444523MM15878
PathwayREACTOME_BICARBONATE_TRANSPORTERS

SLC4A8 SLC4A10

5.89e-0410522M27335
PathwayREACTOME_BICARBONATE_TRANSPORTERS

SLC4A8 SLC4A10

5.89e-0410522MM15073
PathwayKEGG_FOLATE_BIOSYNTHESIS

ALPI ALPG

7.19e-0411522M2220
PathwayWP_WNT_SIGNALING_WP428

FZD1 SFRP4 FZD5 CCND2

7.88e-04113524M39669
PathwayWP_OSTEOBLAST_DIFFERENTIATION_AND_RELATED_DISEASES

FZD1 FZD4 FZD5 WNT8B

9.26e-04118524M39852
PathwayREACTOME_INDUCTION_OF_CELL_CELL_FUSION

ANO4 ANO2

1.01e-0313522M46426
PathwayWP_PLEURAL_MESOTHELIOMA

FZD1 COL4A2 SFRP4 PIGF FZD5 MAP3K5 CCND2

1.08e-03439527M42563
PathwayKEGG_PATHWAYS_IN_CANCER

FZD1 FZD4 COL4A2 FZD5 WNT8B NOS2

1.20e-03325526M12868
PathwayWP_ALZHEIMERS_DISEASE_AND_MIRNA_EFFECTS

FZD1 SFRP4 FZD5 NOS2 RYR3 MAP3K5

1.21e-03326526M39379
PathwayREACTOME_ASYMMETRIC_LOCALIZATION_OF_PCP_PROTEINS

FZD1 FZD4 FZD5

1.40e-0360523MM15150
PathwayREACTOME_ASYMMETRIC_LOCALIZATION_OF_PCP_PROTEINS

FZD1 FZD4 FZD5

1.68e-0364523M27396
PathwayWP_REGULATION_OF_WNT_BCATENIN_SIGNALING_BY_SMALL_MOLECULE_COMPOUNDS

FZD1 SFRP4

1.75e-0317522M39525
PathwayWP_PHYSICOCHEMICAL_FEATURES_AND_TOXICITYASSOCIATED_PATHWAYS

FZD1 FZD4 FZD5

1.84e-0366523M39642
PathwayREACTOME_LATE_SARS_COV_2_INFECTION_EVENTS

ANO4 ANO2 GALNT1

2.18e-0370523M46438
PathwayREACTOME_REGULATION_OF_FZD_BY_UBIQUITINATION

FZD4 FZD5

2.43e-0320522MM15155
PathwayWP_CANCER_PATHWAYS

FZD1 FZD4 COL4A2 FZD5 WNT8B NOS2 CCND2

2.46e-03507527M48302
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

OR1Q1 APLNR FSHR P2RY13 OR1A2

2.63e-03260525M39397
PathwayWP_GPCRS_ODORANT

OR8A1 OR2Y1 OR5H2 OR4B1

2.65e-03157524MM15872
PathwayREACTOME_REGULATION_OF_FZD_BY_UBIQUITINATION

FZD4 FZD5

2.68e-0321522M27401
PathwayREACTOME_DIGESTION

ALPI ALPG

2.68e-0321522MM15526
PathwayREACTOME_TCF_DEPENDENT_SIGNALING_IN_RESPONSE_TO_WNT

FZD1 FZD4 FZD5 WNT8B

2.71e-03158524MM14791
PathwayREACTOME_PCP_CE_PATHWAY

FZD1 FZD4 FZD5

3.78e-0385523MM15041
PathwayREACTOME_DIGESTION_AND_ABSORPTION

ALPI ALPG

3.79e-0325522MM15557
PathwayREACTOME_PCP_CE_PATHWAY

FZD1 FZD4 FZD5

4.72e-0392523M27322
PathwayKEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_WNT_INHIBITOR

SFRP4 WNT8B

4.74e-0328522M47835
PathwayWP_DYSREGULATED_MIRNA_TARGETING_IN_INSULINPI3KAKT_SIGNALING

COL4A2 CCND2

4.74e-0328522MM15957
PathwayREACTOME_POST_TRANSLATIONAL_MODIFICATION_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS

PIGF ALPI ALPG

4.86e-0393523M26985
PathwayREACTOME_STIMULI_SENSING_CHANNELS

ANO4 ANO2 RYR3

5.79e-0399523MM14910
PathwayREACTOME_POST_TRANSLATIONAL_MODIFICATION_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS

PIGF ALPI ALPG

5.79e-0399523MM14624
Pubmed

A role for Wnt/beta-catenin signaling in lens epithelial differentiation.

FZD1 FZD4 SFRP4 FZD5 WNT8B

1.37e-092569512812787
Pubmed

Different evolutionary processes shaped the mouse and human olfactory receptor gene families.

OR8A1 OR10J5 OR8B4 OR12D2 OR1Q1 OR2Y1 OR1A2 OR5H2 OR4B1 OR4A4P

1.43e-09340691011875048
Pubmed

The olfactory receptor gene superfamily of the mouse.

OR8A1 OR10J5 OR8B4 OR12D2 OR1Q1 OR2Y1 OR1A2 OR5H2 OR4B1 OR4A4P

1.43e-09340691011802173
Pubmed

A unified nomenclature for vertebrate olfactory receptors.

OR8A1 OR10J5 OR8B4 OR12D2 OR1Q1 OR2Y1 OR1A2 OR5H2 OR4B1 OR4A4P

1.55e-09343691032295537
Pubmed

Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.

OR8A1 OR10J5 OR8B4 OR12D2 OR1Q1 OR2Y1 OR1A2 OR5H2 OR4B1 OR4A4P

1.69e-09346691014611657
Pubmed

Integrated analysis of Wnt signalling system component gene expression.

FZD1 FZD4 SFRP4 FZD5 WNT8B

1.10e-083769535831952
Pubmed

Wnt11 promotes cardiomyocyte development by caspase-mediated suppression of canonical Wnt signals.

FZD1 FZD4 SFRP4 FZD5 WNT8B

1.27e-083869521041481
Pubmed

Conditional mutations of beta-catenin and APC reveal roles for canonical Wnt signaling in lens differentiation.

FZD1 FZD4 SFRP4 FZD5 WNT8B CCND2

2.67e-089069619515997
Pubmed

Mapping of Wnt-Frizzled interactions by multiplex CRISPR targeting of receptor gene families.

FZD1 FZD4 FZD5 WNT8B

3.31e-081769428733458
Pubmed

Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells.

FZD1 FZD4 SFRP4 FZD5 WNT8B

4.73e-084969519562671
Pubmed

The human olfactory receptor gene family.

OR8A1 OR10J5 OR8B4 OR12D2 OR1Q1 OR2Y1 OR1A2 OR5H2 OR4B1 OR4A4P

1.14e-07541691014983052
Pubmed

Autosomal dominant familial exudative vitreoretinopathy in two Japanese families with FZD4 mutations (H69Y and C181R).

FZD1 FZD4 FZD5

2.60e-07769315370539
Pubmed

DEFOG: a practical scheme for deciphering families of genes.

OR8A1 OR8B4 OR1Q1 OR2Y1 OR1A2 OR4B1 OR4A4P

2.76e-0721969712213199
Pubmed

3D representation of Wnt and Frizzled gene expression patterns in the mouse embryo at embryonic day 11.5 (Ts19).

FZD1 FZD4 FZD5 WNT8B

3.25e-072969418364260
Pubmed

Differential expression of the Wnt putative receptors Frizzled during mouse somitogenesis.

FZD1 FZD4 FZD5

4.16e-07869310559494
Pubmed

A coated vesicle-associated kinase of 104 kDa (CVAK104) induces lysosomal degradation of frizzled 5 (Fzd5).

FZD1 FZD4 FZD5

4.16e-07869319643732
Pubmed

A novel frizzled gene identified in human esophageal carcinoma mediates APC/beta-catenin signals.

FZD1 FZD4 FZD5

6.22e-0796939707618
Pubmed

Expression of Frizzled genes in developing and postnatal hair follicles.

FZD1 FZD4 FZD5

8.88e-071069315245425
Pubmed

Essential roles of mesenchyme-derived beta-catenin in mouse Müllerian duct morphogenesis.

FZD1 FZD4 FZD5

8.88e-071069317532316
Pubmed

Canonical WNT signaling promotes mammary placode development and is essential for initiation of mammary gland morphogenesis.

FZD1 FZD4 FZD5 WNT8B

8.92e-073769415342465
Pubmed

Tissue-specific requirements of beta-catenin in external genitalia development.

FZD1 FZD4 FZD5 WNT8B

9.95e-073869418635608
Pubmed

Frizzled-9 impairs acetylcholine receptor clustering in skeletal muscle cells.

FZD1 FZD4 FZD5

1.22e-061169324860427
Pubmed

Molecular determinants of WNT9b responsiveness in nephron progenitor cells.

FZD1 FZD4 FZD5

1.22e-061169330978219
Pubmed

Distinct but redundant expression of the Frizzled Wnt receptor genes at signaling centers of the developing mouse brain.

FZD1 FZD4 FZD5

1.22e-061169317582687
Pubmed

Expression of Frizzled5, Frizzled7, and Frizzled10 during early mouse development and interactions with canonical Wnt signaling.

FZD1 FZD4 FZD5

1.22e-061169317576136
Pubmed

Stromal R-spondin orchestrates gastric epithelial stem cells and gland homeostasis.

FZD1 FZD4 FZD5 WNT8B

2.37e-064769428813421
Pubmed

Malformation of Tear Ducts Underlies the Epiphora and Precocious Eyelid Opening in Prickle 1 Mutant Mice: Genetic Implications for Tear Duct Genesis.

FZD1 FZD4 FZD5 WNT8B

2.37e-064769433141892
Pubmed

Information coding in the olfactory system: evidence for a stereotyped and highly organized epitope map in the olfactory bulb.

OR8A1 OR10J5 OR2Y1

2.68e-06146937528109
Pubmed

K+-Driven Cl-/HCO3- Exchange Mediated by Slc4a8 and Slc4a10.

SLC4A8 SLC4A10

3.88e-06269238674160
Pubmed

Cardiac hypertrophy is associated with altered thioredoxin and ASK-1 signaling in a mouse model of menopause.

FSHR MAP3K5

3.88e-06269218676690
Pubmed

Spontaneous and sensory-evoked activity in mouse olfactory sensory neurons with defined odorant receptors.

OR8A1 OR10J5

3.88e-06269223596334
Pubmed

Minigenes impart odorant receptor-specific axon guidance in the olfactory bulb.

OR8A1 OR10J5

3.88e-06269212194868
Pubmed

Efficient transposition of the piggyBac (PB) transposon in mammalian cells and mice.

ANO2 ZFHX4 DHX9

4.11e-061669316096065
Pubmed

The chromosomal distribution of mouse odorant receptor genes.

OR8A1 OR10J5 OR2Y1 OR4B1

4.16e-06546948570653
Pubmed

Mesenchymal Hox6 function is required for mouse pancreatic endocrine cell differentiation.

FZD4 SFRP4 FZD5 WNT8B

5.95e-065969426450967
Pubmed

Expression of the Wnt inhibitor Dickkopf-1 is required for the induction of neural markers in mouse embryonic stem cells differentiating in response to retinoic acid.

FZD1 FZD4 FZD5

1.12e-052269317064353
Pubmed

Two gene duplication events in the evolution of the human heat-stable alkaline phosphatases.

ALPI ALPG

1.16e-0536923443302
Pubmed

Role of lysophosphatidylcholine in brush-border intestinal alkaline phosphatase release and restoration.

ALPI ALPG

1.16e-05369219407215
Pubmed

Genomic structure and comparison of mouse tissue-specific alkaline phosphatase genes.

ALPI ALPG

1.16e-0536922286375
Pubmed

Intestinal Alkaline Phosphatase Regulates Tight Junction Protein Levels.

ALPI ALPG

1.16e-05369227106638
Pubmed

Organic pyrophosphates as substrates for human alkaline phosphatases.

ALPI ALPG

1.16e-05369216742561
Pubmed

Effects of disruption of the embryonic alkaline phosphatase gene on preimplantation development of the mouse.

ALPI ALPG

1.16e-05369210767088
Pubmed

MUSEAP, a novel reporter gene for the study of long-term gene expression in immunocompetent mice.

ALPI ALPG

1.16e-05369211722850
Pubmed

A novel phosphatase upregulated in Akp3 knockout mice.

ALPI ALPG

1.16e-05369217901166
Pubmed

Wnt2b controls retinal cell differentiation at the ciliary marginal zone.

FZD4 FZD5

1.16e-05369212490564
Pubmed

A family of secreted proteins contains homology to the cysteine-rich ligand-binding domain of frizzled receptors.

FZD4 SFRP4 FZD5

1.47e-05246939096311
Pubmed

Odorant and vomeronasal receptor genes in two mouse genome assemblies.

OR12D2 OR2Y1 OR1A2 OR4B1

1.47e-057469415081110
Pubmed

Modulation of the combinatorial code of odorant receptor response patterns in odorant mixtures.

OR10J5 OR2Y1 OR5H2

2.11e-052769332061665
Pubmed

Activation of the Wnt-beta catenin pathway in a cell population on the surface of the forebrain is essential for the establishment of olfactory axon connections.

FZD1 FZD4 WNT8B

2.11e-052769317804636
Pubmed

Interactions between CD36 and global intestinal alkaline phosphatase in mouse small intestine and effects of high-fat diet.

ALPI ALPG

2.32e-05469221900644
Pubmed

Absence of adenylyl cyclase 3 perturbs peripheral olfactory projections in mice.

OR8A1 OR10J5

2.32e-05469217581954
Pubmed

Novel Role of the ALPI Gene Associated with Constipation Caused by Complement Component 3 Deficiency.

ALPI ALPG

2.32e-05469239273477
Pubmed

Structural evidence of functional divergence in human alkaline phosphatases.

ALPI ALPG

2.32e-05469212372831
Pubmed

Amyloid-beta binds to the extracellular cysteine-rich domain of Frizzled and inhibits Wnt/beta-catenin signaling.

FZD4 FZD5

2.32e-05469218234671
Pubmed

Stage-specific expression patterns of alkaline phosphatase during development of the first arch skeleton in inbred C57BL/6 mouse embryos.

ALPI ALPG

2.32e-0546929061447
Pubmed

G protein-coupled odorant receptors underlie mechanosensitivity in mammalian olfactory sensory neurons.

OR8A1 OR10J5

2.32e-05469225550517
Pubmed

Inactivation of two mouse alkaline phosphatase genes and establishment of a model of infantile hypophosphatasia.

ALPI ALPG

2.32e-0546929056646
Pubmed

FLJ10261 gene, located within the CCND1-EMS1 locus on human chromosome 11q13, encodes the eight-transmembrane protein homologous to C12orf3, C11orf25 and FLJ34272 gene products.

ANO4 ANO2

2.32e-05469212739008
Pubmed

Conditional ablation of the Notch2 receptor in the ocular lens.

SFRP4 WNT8B CCND2

3.23e-053169322173065
Pubmed

Immunocytochemical identification of electroneutral Na⁺-coupled HCO₃⁻ transporters in freshly dissociated mouse medullary raphé neurons.

SLC4A8 SLC4A10

3.86e-05569223500099
Pubmed

Non-association between polymorphisms of the frizzled receptor genes and bone mineral density in postmenopausal Korean women.

FZD1 FZD5

3.86e-05569219543507
Pubmed

Ca2+-activated Cl− currents are dispensable for olfaction.

OR8A1 ANO2

3.86e-05569221516098
Pubmed

Central role of pyrophosphate in acellular cementum formation.

ALPI ALPG

3.86e-05569222675556
Pubmed

Secreted Frizzled-related protein-1 is a negative regulator of androgen receptor activity in prostate cancer.

FZD1 FZD4

3.86e-05569219277043
Pubmed

Two alkaline phosphatase genes are expressed during early development in the mouse embryo.

ALPI ALPG

3.86e-0556922133555
Pubmed

Germ cell nuclear antigen (GCNA1) expression does not require a gonadal environment or steroidogenic factor 1: examination of GCNA1 in ectopic germ cells and in Ftz-F1 null mice.

ALPI ALPG

3.86e-0556929291464
Pubmed

Differential impact of Lhx2 deficiency on expression of class I and class II odorant receptor genes in mouse.

OR8A1 OR10J5 OR2Y1

3.91e-053369317350283
Pubmed

Wnt/Rspondin/β-catenin signals control axonal sorting and lineage progression in Schwann cell development.

FZD1 FZD4 FZD5

5.09e-053669324151333
Pubmed

Expression patterns of Wnts, Frizzleds, sFRPs, and misexpression in transgenic mice suggesting a role for Wnts in pancreas and foregut pattern formation.

FZD4 SFRP4 FZD5

5.09e-053669312412008
Pubmed

Patterns of Wnt/Fzd/LRP gene expression during embryonic hematopoiesis.

FZD1 FZD4 FZD5

5.53e-053769318800919
Pubmed

Disrupted compartmental organization of axons and dendrites within olfactory glomeruli of mice deficient in the olfactory cell adhesion molecule, OCAM.

OR8A1 OR10J5

5.79e-05669216531066
Pubmed

Hydrolysis and absorption of pantothenate and its coenzymes in the rat small intestine.

ALPI ALPG

5.79e-0566926619987
Pubmed

Dissection of the odontoblast differentiation process in vitro by a combination of FGF1, FGF2, and TGFbeta1.

ALPI ALPG

5.79e-05669210878613
Pubmed

WNT signaling pathway gene polymorphisms and risk of hepatic fibrosis and inflammation in HCV-infected patients.

FZD1 FZD4

5.79e-05669224386373
Pubmed

Multiplex assessment of the positions of odorant receptor-specific glomeruli in the mouse olfactory bulb by serial two-photon tomography.

OR8A1 OR10J5

5.79e-05669226450880
Pubmed

Cutting edge: apoptosis-regulating signal kinase 1 is required for reactive oxygen species-mediated activation of IFN regulatory factor 3 by lipopolysaccharide.

NOS2 MAP3K5

5.79e-05669216670275
Pubmed

Identification and characterization of TMEM16E and TMEM16F genes in silico.

ANO4 ANO2

5.79e-05669215067359
Pubmed

Linear correlation between the number of olfactory sensory neurons expressing a given mouse odorant receptor gene and the total volume of the corresponding glomeruli in the olfactory bulb.

OR8A1 OR10J5

5.79e-05669226100963
Pubmed

Replacement of Lost Lgr5-Positive Stem Cells through Plasticity of Their Enterocyte-Lineage Daughters.

ALPI ALPG

8.09e-05769226831517
Pubmed

MAGI-3 is involved in the regulation of the JNK signaling pathway as a scaffold protein for frizzled and Ltap.

FZD4 FZD5

8.09e-05769215195140
Pubmed

The protocadherin-alpha family is involved in axonal coalescence of olfactory sensory neurons into glomeruli of the olfactory bulb in mouse.

OR8A1 OR10J5

8.09e-05769218353676
Pubmed

ANOs 3-7 in the anoctamin/Tmem16 Cl- channel family are intracellular proteins.

ANO4 ANO2

8.09e-05769222075693
Pubmed

Wnt7b activates canonical signaling in epithelial and vascular smooth muscle cells through interactions with Fzd1, Fzd10, and LRP5.

FZD1 FZD4

8.09e-05769215923619
Pubmed

PlexinA1 signaling directs the segregation of proprioceptive sensory axons in the developing spinal cord.

FZD1 FZD4 LRFN2 FZD5

8.88e-0511769417145500
Pubmed

Alteration of Nrp1 signaling at different stages of olfactory neuron maturation promotes glomerular shifts along distinct axes in the olfactory bulb.

OR8A1 OR10J5

1.08e-04869227578798
Pubmed

Dysfunction of Wnt signaling and synaptic disassembly in neurodegenerative diseases.

FZD1 FZD5

1.08e-04869224449494
Pubmed

Sequence requirement and subtype specificity in the high-affinity interaction between human frizzled and dishevelled proteins.

FZD1 FZD4

1.08e-04869219388021
Pubmed

Members of the WNT signaling pathways are widely expressed in mouse ovaries, oocytes, and cleavage stage embryos.

FZD1 FZD4 FZD5

1.14e-044769318351675
Pubmed

Brg1 plays an essential role in development and homeostasis of the duodenum through regulation of Notch signaling.

FZD1 FZD4 FZD5

1.37e-045069327510977
Pubmed

ER stress transforms random olfactory receptor choice into axon targeting precision.

OR8A1 OR10J5

1.38e-04969236167070
Pubmed

Adenylyl cyclase-dependent axonal targeting in the olfactory system.

OR8A1 OR10J5

1.38e-04969217537788
Pubmed

The Zonal Organization of Odorant Receptor Gene Choice in the Main Olfactory Epithelium of the Mouse.

OR8A1 OR10J5

1.38e-04969232209480
Pubmed

A role for the Wnt gene family in hematopoiesis: expansion of multilineage progenitor cells.

FZD4 FZD5

1.38e-0496929160667
Pubmed

Direct interaction of Frizzled-1, -2, -4, and -7 with PDZ domains of PSD-95.

FZD1 FZD4

1.38e-04969212067714
Pubmed

A Runx2/miR-3960/miR-2861 regulatory feedback loop during mouse osteoblast differentiation.

ALPI ALPG

1.38e-04969221324897
Pubmed

Genomic analysis of mouse retinal development.

FZD1 FZD4 POLR3K ZFHX4 ARL6IP1 TMEM94 FZD5 ZNF595 CCND2

1.64e-04100669915226823
Pubmed

Multimodal spatiotemporal transcriptomic resolution of embryonic palate osteogenesis.

ALPI ALPG

1.73e-041069237709732
Pubmed

Anoctamin/TMEM16 family members are Ca2+-activated Cl- channels.

ANO4 ANO2

1.73e-041069219015192
Pubmed

Calcium-dependent phospholipid scramblase activity of TMEM16 protein family members.

ANO4 ANO2

1.73e-041069223532839
Pubmed

Structure and function of TMEM16 proteins (anoctamins).

ANO4 ANO2

1.73e-041069224692353
Cytoband2p21-p16

PIGF FSHR

1.33e-0546922p21-p16
GeneFamilyG protein-coupled receptors, Class F frizzled

FZD1 FZD4 FZD5

4.82e-0611573286
GeneFamilyAlkaline phosphatases

ALPI ALPG

5.84e-0545721072
GeneFamilyAnoctamins

ANO4 ANO2

4.32e-0410572865
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZFHX4 ZHX1

9.99e-0415572529
GeneFamilyOlfactory receptors, family 1

OR1Q1 OR1A2

7.05e-0340572147
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF177 ZNF217 ZNF772 ZHX1 ZNF595 ZNF292 ZNF646

7.13e-0371857728
GeneFamilyOlfactory receptors, family 8

OR8A1 OR8B4

1.04e-0249572155
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-Like-Differentiating_AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLC4A8 ZFHX4 APLNR PPP4R4 RYR3

1.67e-061286952cf0384240a4a663869cf6b27d954236f6214a9a
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_bronchial_vessel|Children_(3_yrs) / Lineage, Cell type, age group and donor

FZD4 COL4A2 KLHL3 ANO2 APLNR

5.47e-06163695977a970b1296234c22178420294cea73506ee02f
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_bronchial_vessel-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

FZD4 COL4A2 KLHL3 ANO2 APLNR

5.47e-06163695ba7d02db0f0e2f9916ec8db52c067c87b6917c23
ToppCellCOVID-19-APC-like-Dendritic_cells|COVID-19 / group, cell type (main and fine annotations)

GRK3 P2RY13 LRRK1 PADI2 ADAM28

9.59e-06183695703364836b42aa6ac6c68b42b700ac23c4a1afc7
ToppCellCOVID-19-APC-like|COVID-19 / group, cell type (main and fine annotations)

GRK3 P2RY13 LRRK1 PADI2 ADAM28

9.59e-06183695b8f5afaf9ff1b2b1bc60be58654d1b23859dafa9
ToppCellfacs-Heart-RV-3m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD4 COL4A2 LRRC8C APLNR NOS2

1.15e-0519069589d1d686cc683206534e2157554d7d0df5d53497
ToppCellfacs-Heart-RV-3m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD4 COL4A2 LRRC8C APLNR NOS2

1.15e-0519069565ba6c4f4a2905c0bf4ff99518ae49e3dfd5e640
ToppCellfacs-Heart-LA-3m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD4 COL4A2 LRRC8C APLNR NOS2

1.18e-05191695a15f0fb4bd7dd77ef5f931b6fc9d68697deec1d1
ToppCellfacs-Heart-LA-3m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD4 COL4A2 LRRC8C APLNR NOS2

1.18e-05191695827be47d3574c6c5b021c6f1c1670834344f10cb
ToppCell356C-Endothelial_cells-Endothelial-A_(Artery)|356C / Donor, Lineage, Cell class and subclass (all cells)

FZD4 COL4A2 KLHL3 ANO2 APLNR

1.27e-051946952e5b195e02dcd5e9432b9a98b22e0478e65b9ba2
ToppCell356C-Endothelial_cells-Endothelial-A_(Artery)-|356C / Donor, Lineage, Cell class and subclass (all cells)

FZD4 COL4A2 KLHL3 ANO2 APLNR

1.27e-05194695b6b5b0ab506b05a005ba8a05a3c7f4c725ba9200
ToppCell5'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

C5orf63 ZNF177 SLC4A10 ZNF595

1.01e-04156694d411116d54add2d4fe649a97ac54cb94c085312f
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FUT9 ASTN2 DNAH5 RYR3

1.22e-041646941cb5fbd7050650047ad6f2ca792118e98d58d22b
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Nptxr-Excitatory_Neuron.Slc17a7.Nptxr-Ndst4_(Superficial_layer_pyramidal_cells--dorsal_endopiriform_nucleus_or_piriform_cortex)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ANO2 FSHR ALPI

1.28e-04636931f609765ed8b3a09095427da5dab7ba03a763192
ToppCellEndothelial-A-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

FZD4 COL4A2 KLHL3 APLNR

1.47e-04172694a3201773a25832e92dd113fad165f1ecd37f5e91
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Myeloid_Dendritic_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CWF19L2 GRK3 CDADC1 ZNF217

1.57e-04175694bb058e714d21a0ec8532eaf3c7dd2faf78016bc0
ToppCellDendritic_Cells-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

P2RY13 RGS21 PADI2 ADAM28

1.57e-04175694584290a51f9975782a5ac8c6ad67c778d8323f8c
ToppCellhuman_hepatoblastoma-Tumor_cells-T6|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

ZFHX4 FUT9 PADI2 CCND2

1.71e-0417969414fc8ccb6b215063d747643f47d780d2b237eb67
ToppCellEndothelial-A-HP_01|World / lung cells shred on cell class, cell subclass, sample id

FZD4 COL4A2 APLNR NOS2

1.75e-041806944c3376169770ee9f9283daae44c17f35e46bfd19
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 FUT9 ASTN2 CFAP61

1.79e-041816946a6bd8e020cb0929b6ecdcb55d467ad24fecfaf0
ToppCellfacs-Heart-LV-3m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRFN2 SLC4A8 GRK3 TMEM94

1.79e-041816941db1eb7d330a7e5090994007ae287e11f0a74450
ToppCellfacs-Heart-LV-3m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRFN2 SLC4A8 GRK3 TMEM94

1.79e-0418169406174ce9240c9261c0f51a1b0d875335d60722e5
ToppCell10x3'2.3-week_14-16-Endothelial-stroma-proliferating_EC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

FZD4 COL4A2 APLNR NOS2

1.82e-04182694997d37ca2af661c92a56add888762724dfccc890
ToppCelltumor_Lymph_Node_/_Brain-Endothelial_cells|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

FZD4 COL4A2 ANO2 APLNR

1.82e-04182694d7cce5dd7046f06bf40f00c9dbfa610722b03333
ToppCellpdx-Tumor_cells-T6|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

ZFHX4 FUT9 PADI2 CCND2

1.82e-041826947b24a4f712e1ae1525e8f1c8ec4e1fc43489cbee
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANO2 ZFHX4 DNAH5 RYR3

1.90e-041846942cbed6462fea2622871bb7e49b0df3d984239281
ToppCell(4)_Endothelial_cells-(40)_EC-arterial|World / Cell class and subclass of bone marrow stroma cells in homeostatis

COL4A2 LRRC8C APLNR NOS2

1.90e-041846947e1a2971321ddcfa00d78d3e3ba7960e532f9392
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANO2 ZFHX4 DNAH5 RYR3

1.90e-04184694ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANO2 ZFHX4 DNAH5 RYR3

1.90e-041846942b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell10x5'v1-week_14-16-Myeloid_neutrophil-granulo-eo/baso/mast-eosinophil|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

OR5H2 ADAM28 RYR3 CCND2

1.90e-04184694ce31684772e47a294155f368e50b49753f7c8e87
ToppCelltumor_Lymph_Node_/_Brain-Endothelial_cells-Tumor_ECs|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

FZD4 COL4A2 ANO2 APLNR

2.02e-04187694be5f8c5802b0fa8cc1e274fdf06b13eb8ceb8ad4
ToppCellEndothelial-A-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

FZD4 COL4A2 ANO2 APLNR

2.06e-041886940824d567356d360fd8e78e840c30529c139f98a1
ToppCellcellseq2-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-VEC|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

KLHL3 CDADC1 LRRK1 KBTBD2

2.11e-04189694bccb3481ffed597c845fe860da658505316105b5
ToppCelldroplet-Heart-HEART-1m-Endothelial-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD4 COL4A2 ANO2 APLNR

2.11e-041896944225bbff4037eecc93a12abad3a38dd04b1e22be
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)--|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

APLNR RGS21 NOS2

2.15e-04756933167beedef7304697e9577270cdeacfc9743cee1
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

APLNR RGS21 NOS2

2.15e-047569370c346f92a9ac7e33fc1b9dee1dca0bf9ae0a38c
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

APLNR RGS21 NOS2

2.15e-047569326d6e54ed0a6c3ff57f6269c460177bc7b8bf979
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 FUT9 ASTN2 DNAH5

2.19e-04191694d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCellControl-Stromal_mesenchymal|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANO4 SFRP4 GRK3 ASTN2

2.19e-0419169414057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCell368C-Myeloid-Dendritic-cDC2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

FZD1 LRRC8C P2RY13 ADAM28

2.19e-0419169485dba3a8a52307df52d1d78a6f278501298f3067
ToppCell10x5'v1-week_12-13-Endothelial-stroma-tip_EC|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

FZD4 COL4A2 APLNR NOS2

2.19e-04191694cf1a67b7c0d5c0dc5d4d59faf9d9b1a3a1fb00e0
ToppCellCOVID-19-Myeloid-DC2|COVID-19 / Condition, Lineage and Cell class

P2RY13 LRRK1 PADI2 ADAM28

2.19e-041916941304ab7b5713f29f3966ffc020ea1b52e8e2f375
ToppCellfacs-Heart-RV-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD4 COL4A2 LRRC8C APLNR

2.19e-0419169484ebb9f8e975acc88aa600c08a8aa791256948a6
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GRK3 P2RY13 LRRK1 ADAM28

2.28e-041936943e3d7cb3e7242ec9c9677e07e303835649852b52
ToppCellChildren_(3_yrs)-Immune-monocyte-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

GRK3 P2RY13 LRRK1 ADAM28

2.28e-0419369458e1930a1d80ad3729ab9604ac8ebf7308232a3d
ToppCellIPF-Endothelial-VE_Capillary_B|World / Disease state, Lineage and Cell class

FZD4 COL4A2 ANO2 APLNR

2.28e-04193694d7750a7575ef257963b7f1c64fa67c52dbff797b
ToppCell10x5'-Lung-Myeloid_Dendritic|Lung / Manually curated celltypes from each tissue

P2RY13 LRRK1 PADI2 ADAM28

2.28e-041936947bce609699c515d2d114596a0c527f90cc09c4af
ToppCell10x5'v1-week_14-16-Endothelial-stroma-proliferating_EC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

FZD4 COL4A2 APLNR GRM2

2.33e-041946948a4be91414a2e69dd410aa75791f16008204c9a1
ToppCell10x5'v1-week_17-19-Endothelial|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

FZD4 COL4A2 APLNR NOS2

2.33e-04194694e141beafc9252e5d8c949252bfab53e127c881dc
ToppCellCOPD-Endothelial-VE_Capillary_B|World / Disease state, Lineage and Cell class

FZD4 COL4A2 ANO2 APLNR

2.33e-0419469468705a6eca947c5b42b943d5224a7aef2a744007
ToppCellIPF-Endothelial-VE_Capillary_B|IPF / Disease state, Lineage and Cell class

FZD4 COL4A2 ANO2 APLNR

2.33e-04194694169a304d5c13f08c39fad4116f093bc4a0765e9d
ToppCellControl-Myeloid-MoAM4|Myeloid / Condition, Lineage and Cell class

P2RY13 LRRK1 ADAM28 CCND2

2.33e-041946947ab808dd1876b0eec2831caa16d04fd859b1dc50
ToppCell10x5'v1-week_17-19-Endothelial-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

FZD4 COL4A2 APLNR NOS2

2.33e-04194694953578102ffc7b612ee8fce45e414750800fef5d
ToppCellPCW_13-14-Endothelial-Endothelial_immature-endo_immature_arterial1_(12)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ANO2 APLNR FUT9 NOS2

2.33e-0419469432ba2cf9b8726bc3c6e9dc24b54d22ff188bb12b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GRK3 P2RY13 LRRK1 ADAM28

2.33e-04194694badefcec2af86cbcd97305f4843e84db0f3ebc66
ToppCellCOPD-Endothelial-VE_Capillary_B|COPD / Disease state, Lineage and Cell class

FZD4 COL4A2 ANO2 APLNR

2.33e-0419469418b7f901c12ca4f21f9a1eafd092aefe4d668b6d
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_3|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

P2RY13 LRRK1 ADAM28 CCND2

2.33e-04194694e56c6e5c9b7d287ae94566b561e21cec2055f83d
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

P2RY13 LRRK1 PADI2 ADAM28

2.37e-041956947bb3bdfb8caaae357b1f7841d8d00936c4373dfe
ToppCellAdult-Immune-monocyte-D231|Adult / Lineage, Cell type, age group and donor

GRK3 P2RY13 PADI2 ADAM28

2.37e-04195694ea24da6fea1487acb1e56c28c0649858cc0a12bd
ToppCell10x5'v1-week_17-19-Endothelial-stroma-sinusoidal_EC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

FZD4 COL4A2 APLNR NOS2

2.37e-0419569422a481927147ec4ae9d59e6af7c87df0e9cb51e4
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_3|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

P2RY13 LRRK1 ADAM28 CCND2

2.37e-0419569485fee07d71c0393ea42bcf1130566dff4a62f507
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

P2RY13 LRRK1 PADI2 ADAM28

2.37e-04195694d579150d176e6bd81004b5146de4901ca13a3c3e
ToppCell(2)_5-FU|World / Stress and Cell class

FZD1 FZD4 COL4A2 FZD5

2.37e-04195694e5b1d96fafeb2f3b1f4cdf6b2c9eddef36bca7ff
ToppCellfacs-Thymus-Thymus_Epithelium|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A2 ZFHX4 DNAH5 RYR3

2.42e-041966946bc1187dfc4860a4e09032d7ea87ba3d9fe9f363
ToppCellfacs-Thymus-Thymus_Epithelium-18m|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A2 ZFHX4 DNAH5 RYR3

2.42e-04196694c8c89e469402e11aa2a9561e859b6fd1fb66c39b
ToppCellAdult-Immune-monocyte|Adult / Lineage, Cell type, age group and donor

GRK3 P2RY13 PADI2 ADAM28

2.42e-041966943ef193c5180de3137daf886492e74fc574bc9767
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GRK3 P2RY13 LRRK1 ADAM28

2.42e-041966944370473693d2dd4a8c451a4c477eb79baa33ae12
ToppCell5'-Adult-LargeIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FZD4 ANO2 APLNR RYR3

2.47e-0419769487eda06344498dc66cac292cf89746dc90b5cf67
ToppCell10x3'2.3-week_17-19-Endothelial-stroma-sinusoidal_EC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

FZD4 COL4A2 KLHL3 APLNR

2.47e-041976944e58bbf3ecb30b4c8199adcc04d2eb134d90de56
ToppCellMonocytes-cDCs|World / Immune cells in Kidney/Urine in Lupus Nephritis

GRK3 P2RY13 PADI2 ADAM28

2.47e-041976943388c104af4c6a05988e102627e0c5e34d9dcc45
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GRK3 P2RY13 LRRK1 ADAM28

2.47e-0419769457dafb3047745a44b2345b8036e159c3641d496e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GRK3 P2RY13 LRRK1 ADAM28

2.52e-0419869496883ad8e189a46ed5b7eaafc0543e53682d26ed
ToppCellmetastatic_Brain-Endothelial_cells|metastatic_Brain / Location, Cell class and cell subclass

FZD4 COL4A2 ANO2 APLNR

2.52e-0419869497ef7946ef11ac93318c1dd46b548dc01e5a6aba
ToppCellmetastatic_Brain-Endothelial_cells-Tumor_ECs|metastatic_Brain / Location, Cell class and cell subclass

FZD4 COL4A2 ANO2 APLNR

2.52e-041986945e274f29cc796dae7d64d6035e904816c25f9914
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GRK3 P2RY13 LRRK1 ADAM28

2.52e-04198694623f9d64c9e800d2d7f623392bf2f22b563f0249
ToppCellBAL-Severe-Myeloid-cDC|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

P2RY13 LRRK1 PADI2 ADAM28

2.56e-041996940b20ae65b9340d844e271acda9e116d98fc1cc69
ToppCelldistal-Hematologic-Myeloid_Dendritic_Type_1-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

P2RY13 LRRK1 PADI2 ADAM28

2.56e-041996943860f30114b54abff91898308df71b8b4e05b51e
ToppCell5'-Adult-SmallIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FZD4 ANO2 APLNR RYR3

2.56e-0419969407bda4ac8ffdce1a865ebc99e46c2a27925ff7a8
ToppCellmLN-Dendritic_cell-cDC1|mLN / Region, Cell class and subclass

FZD1 SFRP4 P2RY13 PADI2

2.56e-041996943e25f096ba69fa43ae08adf9ef194ec7ba463fcf
ToppCellBAL-Severe-Myeloid-cDC-cDC|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

P2RY13 LRRK1 PADI2 ADAM28

2.56e-04199694bb9e7418468b88cdfaa78788d062362794ea8230
ToppCellmLN-(5)_Dendritic_cell-(51)_cDC1|mLN / shred on region, Cell_type, and subtype

FZD1 SFRP4 P2RY13 PADI2

2.56e-04199694041353e2d06241b98845a288f90339f30ea722dd
ToppCellBAL-Severe-Myeloid-cDC-cDC|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

P2RY13 LRRK1 PADI2 ADAM28

2.56e-041996949a0e853693e572c63b135f937b2cffd4dd4026fb
ToppCellSevere_COVID-19-Myeloid-cDC|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）

P2RY13 LRRK1 PADI2 ADAM28

2.56e-041996949132c1929d3445fcca49f76f010ca37adeb70315
ToppCellBAL-Severe-Myeloid-cDC|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

P2RY13 LRRK1 PADI2 ADAM28

2.56e-04199694d017848256704ae7237030868b143c3f0842a9c3
ToppCellParenchymal-NucSeq-Immune_Myeloid-Dendritic_cell-DC_activated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

P2RY13 LRRK1 PADI2 ZNF646

2.56e-0419969482759af613ebfffe037afda55159bf6af812c3ac
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FZD4 COL4A2 LRRC8C ANO2

2.56e-0419969463c01e8961f48ed1bed4ab619cacf318cd6de7b9
ToppCellHematolymphoid-Microglia-TYROBP----L1-3|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

P2RY13 LRRK1 ADAM28 MAP3K5

2.61e-04200694a20dce14f94777687aad57d6fbe3258ad376f63f
ToppCellParenchymal-NucSeq-Immune_Myeloid-Dendritic_cell|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

P2RY13 LRRK1 PADI2 ADAM28

2.61e-04200694f19b729b03b5f225b9ed676f0ac31071a4354da3
ToppCellHematolymphoid-Microglia-TYROBP--|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

P2RY13 LRRK1 ADAM28 MAP3K5

2.61e-04200694dc344b3ec51d506952e38f0b3a7795d65f9dd4eb
ToppCellParenchymal-10x5prime-Immune_Myeloid-Dendritic_cell|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

P2RY13 LRRK1 PADI2 ADAM28

2.61e-042006941adebb306112bfc4926678de80f70d35dd57a586
ToppCellHematolymphoid-Microglia-TYROBP-|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

P2RY13 LRRK1 ADAM28 MAP3K5

2.61e-042006943bba5219453322198e8fdb0921d5f8c403598751
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ZFHX4 FUT9 PPP4R4 RYR3

2.61e-0420069407d942803360e1a1e8e131d6e31c726dd0db1a0b
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ZFHX4 FUT9 PPP4R4 RYR3

2.61e-04200694d0812817ef99608994193787a62d39adeb2070ca
ToppCellHematolymphoid-Microglia|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

P2RY13 LRRK1 ADAM28 MAP3K5

2.61e-0420069421bcca3b670fe9bac034aef2275d3de4a9a73e2b
ToppCell10x5'v1-week_14-16-Endothelial-stroma-sinusoidal_EC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

FZD4 COL4A2 KLHL3 APLNR

2.61e-04200694ae429f2de652cc1976e63644781197e9ce0e70c8
ToppCellHematolymphoid-Microglia-TYROBP---|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

P2RY13 LRRK1 ADAM28 MAP3K5

2.61e-04200694a8646d0fca99f10827c2d2a12e584660ef7155f1
ToppCellHematolymphoid-Microglia-TYROBP|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

P2RY13 LRRK1 ADAM28 MAP3K5

2.61e-0420069433036d21c1c82109284473a515c4f890b33fdd5c
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ZFHX4 FUT9 PPP4R4 RYR3

2.61e-04200694cd54ddf1919c98e84b7e4aba85b374fc8b407206
Diseasegranulosa cell tumor (is_marker_for)

FSHR CCND2

2.59e-0411652DOID:2999 (is_marker_for)
Diseaserotator cuff tear, shoulder impingement syndrome

C5orf63 ASTN2

3.11e-0412652EFO_1001178, EFO_1001250
Diseaseanemia (implicated_via_orthology)

SLC4A8 SLC4A10

4.93e-0415652DOID:2355 (implicated_via_orthology)
DiseaseCardiovascular Abnormalities

NOS2 ZNF292

5.62e-0416652C0243050
Diseaseimpotence (biomarker_via_orthology)

NOS2 CCND2

1.07e-0322652DOID:1875 (biomarker_via_orthology)
DiseaseRetinal Diseases

FZD4 NOS2

1.62e-0327652C0035309
DiseaseDrug habituation

ANO4 PRPF4 C5orf63

2.11e-03115653C0013170
DiseaseSubstance-Related Disorders

ANO4 PRPF4 C5orf63

2.11e-03115653C0236969
DiseaseDrug abuse

ANO4 PRPF4 C5orf63

2.11e-03115653C0013146
DiseaseDrug Use Disorders

ANO4 PRPF4 C5orf63

2.11e-03115653C0013222
DiseaseDrug Dependence

ANO4 PRPF4 C5orf63

2.11e-03115653C1510472
DiseaseSubstance Dependence

ANO4 PRPF4 C5orf63

2.11e-03115653C0038580
DiseaseSubstance Use Disorders

ANO4 PRPF4 C5orf63

2.11e-03115653C0038586
DiseaseOrganic Mental Disorders, Substance-Induced

ANO4 PRPF4 C5orf63

2.11e-03115653C0029231
DiseasePrescription Drug Abuse

ANO4 PRPF4 C5orf63

2.11e-03115653C4316881
DiseaseSubstance abuse problem

ANO4 PRPF4 C5orf63

2.17e-03116653C0740858

Protein segments in the cluster

PeptideGeneStartEntry
CGAFYCLRMFKSPDM

C5orf63

116

A6NC05
CLRMFKSPDMTCCFY

C5orf63

121

A6NC05
CMTYAFHTPDKLCFI

GRK3

256

P35626
PFRLQCSMFFSFCEK

CFAP61

926

Q8NHU2
CPSTICVMDKALSFY

ADAM28

356

Q9UKQ2
CYCMTFIFIAKPSTA

GRM2

616

Q14416
SCLARFSTMPFLYCN

COL4A2

1536

P08572
SCFVMFLCLADYLVP

ARL6IP1

71

Q15041
DLYFSRKPCSACLKM

CDADC1

126

Q9BWV3
NAFTMCPLCDKSCDY

ANO2

406

Q9NQ90
DKYCPFMRLSDSCVY

ANO4

401

Q32M45
IFMFCGCVEEYKLAP

ASTN2

731

O75129
MESRCYGCAVKFTLF

ZFYVE19

76

Q96K21
LCYSCVFTPKMLNDF

OR8B4

71

Q96RC9
ALCATDFKFAMYPPS

CCND2

186

P30279
CDFDLFLMNIFPYCT

APLNR

281

P35414
FSCAFNPKVVCMDKY

NOS2

561

P35228
NFYCDIMPLLKLSCS

OR1A2

176

Q9Y585
KDPTFATFMYELCCG

LRRK1

1521

Q38SD2
CFMACLLIYIKPTNS

FUT9

21

Q9Y231
FFCEMPVFLKLACAD

OR2Y1

176

Q8NGV0
HFYCDIIPLFMISCT

OR5H2

181

Q8NGV7
QMEKCLYCFDSSQFP

CWF19L2

671

Q2TBE0
EFPCHKMVLATCSSY

KBTBD2

41

Q8IY47
TYLFFKTRSCSMLCK

OR12D2

221

P58182
PVSVFVCCMKDNYLF

PADI2

306

Q9Y2J8
CMDPLIYIFLCKKFT

P2RY13

311

Q9BPV8
MAFAACLEPYTACDL

ALPI

481

P09923
MAFAACLEPYTACDL

ALPG

481

P10696
CSAELKFFLCSMYAP

FZD1

161

Q9UP38
KFFLCSMYAPVCTVL

FZD1

166

Q9UP38
FFLCSVYVPMCTEKI

FZD4

96

Q9ULV1
IQCSPDLRFFLCSMY

FZD5

76

Q13467
DMFLLLYFSECNKCD

GALNT1

21

Q10472
TDVKGCSMYVALFPC

DCTD

96

P32321
CSMYVALFPCNECAK

DCTD

101

P32321
TFMKYVDSNLCCFIP

FBXO28

156

Q9NVF7
VVLAACSPYFCAMFT

KLHL3

66

Q9UH77
DFFILLSKCGCYEMQ

FSHR

636

P23945
IDTSMFCEYFFNCPI

DHX9

546

Q08211
FSECCPLLEYMASKA

DNAH5

1476

Q8TE73
SHYFCDILPLMKLSC

OR8A1

191

Q8NGG7
FFCDIYPVMKLSCID

OR10J5

176

Q8NHC4
HFFCDLYALMKISCT

OR1Q1

176

Q15612
FCDMYPLLKLACTDT

OR4A4P

176

Q8NGN8
KSLDSPMYFFLSCLS

OR4B1

51

Q8NGF8
MITPHNKVYCCDSSF

MAP3K5

216

Q99683
YCLMAKDSFPRFLKS

RGS21

116

Q2M5E4
KNFHMELYSTFFCLC

PPP4R4

391

Q6NUP7
KLCLVSMDFCFPLDF

TMEM191A

16

Q9H0A3
KVTGFLKCCIYFLMS

PIGF

76

Q07326
LKCCIYFLMSCFSFH

PIGF

81

Q07326
YCHFSPNSKMLATAC

PRPF4

236

O43172
NKCFLSTACGTDFYM

PDIK1L

211

Q8N165
SFLFLYCACMSPVIT

SLC4A8

481

Q2Y0W8
MFLSKPSVYICLFTC

WNT8B

1

Q93098
PVLMCFLCKLSFGYI

ZFHX4

276

Q86UP3
KPFKCTECGRSFYMS

ZNF595

171

Q8IYB9
EMPYECSDCGKAFIF

ZNF177

281

Q13360
VACCRMYPTLDFLKS

SPATA46

186

Q5T0L3
CSAFAYKPMNCALSS

TMEM94

746

Q12767
FPKMVASCCRFLCYF

RYR3

2086

Q15413
FLCAMYAPICTLEFL

SFRP4

76

Q6FHJ7
ASFLFLYCACMSPVI

SLC4A10

511

Q6U841
CMFPKCGRIFSEAYL

ZNF292

781

O60281
YPCAICFKEFSNLMA

ZNF646

266

O15015
ECKYCTFQTPDLNMF

ZHX1

71

Q9UKY1
SADEPMTTFYKCCNA

POLR3K

86

Q9Y2Y1
ISSPYKICMVCGFLF

ZNF217

211

O75362
FDFMLYAKPCCAVDP

UBR4

3711

Q5T4S7
PYMCVLCGKQFCFSA

ZNF772

171

Q68DY9
TMAHLFSKLSFCYLC

LRRC8C

311

Q8TDW0
FGMAFAVVDACPKYC

LRFN2

11

Q9ULH4