Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor activity

VLDLR STAB2 LRP2 LRP1B STAB1

8.80e-1016605GO:0005041
GeneOntologyMolecularFunctionlipoprotein particle receptor activity

VLDLR STAB2 LRP2 LRP1B STAB1

4.05e-0921605GO:0030228
GeneOntologyMolecularFunctionextracellular matrix structural constituent

CRELD1 NID2 FBN2 VWF TNC TECTA TNXB MUC6

8.96e-08188608GO:0005201
GeneOntologyMolecularFunctioncalcium ion binding

CD93 CRELD1 NID2 VLDLR EYS SCUBE1 STAB2 FBN2 JAG1 LRP2 LRP4 LRP1B STAB1

2.66e-077496013GO:0005509
GeneOntologyMolecularFunctionendopeptidase activity

PCSK1 PCSK2 TMPRSS15 ATP23 ADAM23 PRSS56 TMPRSS3 PRSS42P ADAM30

5.12e-06430609GO:0004175
GeneOntologyMolecularFunctioncargo receptor activity

VLDLR STAB2 LRP2 LRP1B STAB1

5.64e-0685605GO:0038024
GeneOntologyMolecularFunctionserine-type endopeptidase activity

PCSK1 PCSK2 TMPRSS15 PRSS56 TMPRSS3 PRSS42P

2.24e-05190606GO:0004252
GeneOntologyMolecularFunctionserine-type peptidase activity

PCSK1 PCSK2 TMPRSS15 PRSS56 TMPRSS3 PRSS42P

3.63e-05207606GO:0008236
GeneOntologyMolecularFunctionserine hydrolase activity

PCSK1 PCSK2 TMPRSS15 PRSS56 TMPRSS3 PRSS42P

4.14e-05212606GO:0017171
GeneOntologyMolecularFunctioncollagen binding

NID2 VWF USH2A TNXB

1.03e-0481604GO:0005518
GeneOntologyMolecularFunctionpeptidase activity

PCSK1 PCSK2 TMPRSS15 ATP23 ADAM23 PRSS56 TMPRSS3 PRSS42P ADAM30

1.36e-04654609GO:0008233
GeneOntologyMolecularFunctionlipoprotein particle binding

VLDLR STAB2 STAB1

1.58e-0435603GO:0071813
GeneOntologyMolecularFunctionprotein-lipid complex binding

VLDLR STAB2 STAB1

1.58e-0435603GO:0071814
GeneOntologyMolecularFunctionstructural molecule activity

CRELD1 NID2 FBN2 VWF TNC JAG1 OBSCN TECTA TNXB MUC6

2.95e-048916010GO:0005198
GeneOntologyMolecularFunctionlow-density lipoprotein particle binding

STAB2 STAB1

1.32e-0318602GO:0030169
GeneOntologyMolecularFunctionapolipoprotein binding

VLDLR LRP4

1.63e-0320602GO:0034185
GeneOntologyMolecularFunctionintegrin binding

VWF ADAM23 TNC TNXB

1.90e-03175604GO:0005178
GeneOntologyMolecularFunctionscavenger receptor activity

STAB2 STAB1

2.97e-0327602GO:0005044
GeneOntologyMolecularFunctionhyaluronic acid binding

STAB2 STAB1

3.42e-0329602GO:0005540
GeneOntologyMolecularFunctionprotein-disulfide reductase activity

STAB2 STAB1

5.24e-0336602GO:0015035
GeneOntologyMolecularFunctionimmunoglobulin binding

VWF FCAMR

5.24e-0336602GO:0019865
GeneOntologyMolecularFunctionmetalloendopeptidase activity

ATP23 ADAM23 ADAM30

5.65e-03120603GO:0004222
GeneOntologyBiologicalProcessinner ear auditory receptor cell differentiation

JAG1 REST TECTA USH2A

4.32e-0567604GO:0042491
GeneOntologyBiologicalProcesshair cell differentiation

JAG1 REST TECTA USH2A

7.86e-0578604GO:0035315
GeneOntologyBiologicalProcesspulmonary artery morphogenesis

JAG1 LRP2

1.24e-046602GO:0061156
GeneOntologyBiologicalProcessnegative regulation of neuron differentiation

JAG1 GPR37L1 REST CASZ1

1.62e-0494604GO:0045665
GeneOntologyBiologicalProcessinner ear receptor cell differentiation

JAG1 REST TECTA USH2A

1.76e-0496604GO:0060113
GeneOntologyBiologicalProcessresponse to vitamin D

STC2 TNC MN1

1.84e-0438603GO:0033280
GeneOntologyBiologicalProcessmechanoreceptor differentiation

JAG1 REST TECTA USH2A

2.39e-04104604GO:0042490
GeneOntologyBiologicalProcesssensory perception of sound

TMPRSS3 LRP2 REST TECTA USH2A

2.76e-04198605GO:0007605
GeneOntologyCellularComponentextracellular matrix

CRELD1 NID2 EYS FCGBP FBN2 VWF ZAN TNC GPC4 TECTA USH2A TNXB MUC6

2.73e-086565913GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

CRELD1 NID2 EYS FCGBP FBN2 VWF ZAN TNC GPC4 TECTA USH2A TNXB MUC6

2.83e-086585913GO:0030312
GeneOntologyCellularComponentcollagen-containing extracellular matrix

CRELD1 NID2 EYS FBN2 VWF TNC GPC4 USH2A TNXB

1.65e-05530599GO:0062023
GeneOntologyCellularComponenttenascin complex

TNC TNXB

4.68e-054592GO:0090733
GeneOntologyCellularComponentcell surface

CD93 NID2 VLDLR SCUBE1 STAB2 VWF GPC4 LRP2 LRP4 ADAM30 ADGRF5 MUSK

5.26e-0511115912GO:0009986
GeneOntologyCellularComponentexternal side of plasma membrane

SCUBE1 STAB2 VWF GPC4 LRP2 ADAM30 MUSK

6.24e-04519597GO:0009897
GeneOntologyCellularComponentside of membrane

SCUBE1 STAB2 VWF GPC4 LRP2 PRSS42P ADAM30 TECTA MUSK

7.25e-04875599GO:0098552
GeneOntologyCellularComponentprotein complex involved in cell-matrix adhesion

TNC TNXB

1.04e-0317592GO:0098637
GeneOntologyCellularComponentclathrin-coated pit

VLDLR LRP2 LRP3

1.50e-0380593GO:0005905
MousePhenoabnormal somatic nervous system morphology

VLDLR SCUBE1 FBN2 JAG1 PRSS56 LPP RXFP2 TMPRSS3 LRP4 REST TECTA MFRP USH2A MUSK

1.91e-0510255314MP:0002752
DomainEGF-like_dom

CD93 CRELD1 NID2 VLDLR EYS SCUBE1 STAB2 FCGBP FBN2 TENM4 ZAN ADAM23 TNC JAG1 LRP2 LRP4 ADAM30 TECTA C9 LRP1B TNXB STAB1

1.97e-262496022IPR000742
DomainEGF_3

CD93 CRELD1 NID2 VLDLR EYS SCUBE1 STAB2 FBN2 TENM4 ZAN ADAM23 TNC JAG1 LRP2 LRP4 ADAM30 C9 LRP1B TNXB STAB1

1.17e-232356020PS50026
DomainEGF

CD93 CRELD1 NID2 VLDLR EYS SCUBE1 STAB2 FCGBP FBN2 TENM4 ZAN ADAM23 TNC JAG1 LRP2 LRP4 TECTA LRP1B TNXB STAB1

1.17e-232356020SM00181
DomainEGF-like_CS

CD93 CRELD1 NID2 VLDLR EYS SCUBE1 STAB2 FBN2 TENM4 ZAN ADAM23 TNC JAG1 LRP2 LRP4 ADAM30 C9 LRP1B TNXB STAB1

9.86e-232616020IPR013032
DomainEGF_2

CD93 CRELD1 NID2 VLDLR EYS SCUBE1 STAB2 FBN2 TENM4 ZAN ADAM23 TNC JAG1 LRP2 LRP4 ADAM30 C9 LRP1B TNXB STAB1

1.34e-222656020PS01186
DomainEGF_1

CRELD1 VLDLR EYS SCUBE1 STAB2 FBN2 TENM4 ZAN ADAM23 TNC JAG1 LRP2 LRP4 ADAM30 C9 USH2A LRP1B TNXB STAB1

2.35e-212556019PS00022
DomainGrowth_fac_rcpt_

CD93 CRELD1 NID2 VLDLR EYS SCUBE1 STAB2 FBN2 TNC JAG1 LRP2 LRP4 C9 LRP1B TNXB STAB1

2.79e-201566016IPR009030
DomainLDLR_class-A_CS

VLDLR TMPRSS15 RXFP2 TMPRSS3 LRP2 LRP3 LRP4 C9 MFRP LRP1B MAMDC4

3.07e-19406011IPR023415
DomainLdl_recept_a

VLDLR TMPRSS15 RXFP2 TMPRSS3 LRP2 LRP3 LRP4 C9 MFRP LRP1B MAMDC4

1.33e-18456011PF00057
Domain-

VLDLR TMPRSS15 RXFP2 TMPRSS3 LRP2 LRP3 LRP4 C9 MFRP LRP1B MAMDC4

1.74e-184660114.10.400.10
DomainEGF

CD93 NID2 VLDLR EYS STAB2 ZAN TNC JAG1 LRP2 LRP4 TECTA LRP1B TNXB STAB1

2.57e-181266014PF00008
DomainLDLRA_1

VLDLR TMPRSS15 RXFP2 TMPRSS3 LRP2 LRP3 LRP4 C9 MFRP LRP1B MAMDC4

2.94e-18486011PS01209
DomainLDLRA_2

VLDLR TMPRSS15 RXFP2 TMPRSS3 LRP2 LRP3 LRP4 C9 MFRP LRP1B MAMDC4

3.78e-18496011PS50068
DomainLDrepeatLR_classA_rpt

VLDLR TMPRSS15 RXFP2 TMPRSS3 LRP2 LRP3 LRP4 C9 MFRP LRP1B MAMDC4

3.78e-18496011IPR002172
DomainLDLa

VLDLR TMPRSS15 RXFP2 TMPRSS3 LRP2 LRP3 LRP4 C9 MFRP LRP1B MAMDC4

3.78e-18496011SM00192
DomainEGF_CA

CD93 CRELD1 NID2 VLDLR EYS SCUBE1 STAB2 FBN2 JAG1 LRP2 LRP4 LRP1B STAB1

8.17e-171226013SM00179
DomainEGF-like_Ca-bd_dom

CD93 CRELD1 NID2 VLDLR EYS SCUBE1 STAB2 FBN2 JAG1 LRP2 LRP4 LRP1B STAB1

1.02e-161246013IPR001881
DomainEGF_Ca-bd_CS

CD93 CRELD1 NID2 VLDLR EYS SCUBE1 FBN2 JAG1 LRP2 LRP4 LRP1B

1.15e-14976011IPR018097
DomainEGF_CA

CD93 CRELD1 NID2 VLDLR EYS SCUBE1 FBN2 JAG1 LRP2 LRP4 LRP1B

1.45e-14996011PS01187
DomainASX_HYDROXYL

CD93 CRELD1 NID2 VLDLR EYS SCUBE1 FBN2 JAG1 LRP2 LRP4 LRP1B

1.63e-141006011PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

CD93 CRELD1 NID2 VLDLR EYS SCUBE1 FBN2 JAG1 LRP2 LRP4 LRP1B

3.14e-141066011IPR000152
DomainEGF_CA

CD93 CRELD1 NID2 VLDLR SCUBE1 FBN2 JAG1 LRP2 LRP4 LRP1B

1.56e-13866010PF07645
DomainEGF_extracell

STAB2 TENM4 ADAM23 TNC JAG1 LRP2 LRP1B TNXB STAB1

2.53e-1360609IPR013111
DomainEGF_2

STAB2 TENM4 ADAM23 TNC JAG1 LRP2 LRP1B TNXB STAB1

2.53e-1360609PF07974
DomaincEGF

CD93 NID2 SCUBE1 FBN2 LRP2 LRP4 LRP1B

1.54e-1226607IPR026823
DomaincEGF

CD93 NID2 SCUBE1 FBN2 LRP2 LRP4 LRP1B

1.54e-1226607PF12662
DomainTIL_dom

FCGBP VWF ZAN LRP2 TECTA MUC6

2.50e-1214606IPR002919
DomainVWC_out

FCGBP VWF ZAN JAG1 TECTA MUC6

2.23e-1119606SM00215
Domain-

NID2 VLDLR TENM4 LRP2 LRP4 HHIPL1 LRP1B

3.49e-11396072.120.10.30
Domain6-blade_b-propeller_TolB-like

NID2 VLDLR TENM4 LRP2 LRP4 HHIPL1 LRP1B

1.19e-1046607IPR011042
DomainTIL

FCGBP VWF ZAN TECTA MUC6

2.25e-1012605PF01826
DomainC8

FCGBP VWF ZAN TECTA MUC6

2.25e-1012605PF08742
DomainUnchr_dom_Cys-rich

FCGBP VWF ZAN TECTA MUC6

3.64e-1013605IPR014853
DomainC8

FCGBP VWF ZAN TECTA MUC6

3.64e-1013605SM00832
DomainLdl_recept_b

NID2 VLDLR LRP2 LRP4 LRP1B

5.65e-1014605PF00058
DomainLDLRB

NID2 VLDLR LRP2 LRP4 LRP1B

5.65e-1014605PS51120
DomainLY

NID2 VLDLR LRP2 LRP4 LRP1B

8.45e-1015605SM00135
DomainLDLR_classB_rpt

NID2 VLDLR LRP2 LRP4 LRP1B

8.45e-1015605IPR000033
DomainVWD

FCGBP VWF ZAN TECTA MUC6

1.23e-0916605SM00216
DomainVWF_type-D

FCGBP VWF ZAN TECTA MUC6

1.23e-0916605IPR001846
DomainVWFD

FCGBP VWF ZAN TECTA MUC6

1.23e-0916605PS51233
DomainVWD

FCGBP VWF ZAN TECTA MUC6

1.23e-0916605PF00094
DomainVWF_dom

FCGBP VWF ZAN JAG1 TECTA MUC6

4.08e-0942606IPR001007
DomainTILa

FCGBP ZAN TECTA

3.15e-083603PF12714
DomainTILa_dom

FCGBP ZAN TECTA

3.15e-083603IPR025615
DomainEGF_3

NID2 SCUBE1 STAB2 STAB1

4.67e-0812604PF12947
DomainEGF_dom

NID2 SCUBE1 STAB2 STAB1

4.67e-0812604IPR024731
DomainVWC

FCGBP VWF ZAN JAG1 TECTA

1.34e-0738605SM00214
Domain-

NID2 STAB2 STAB1

5.11e-06116032.40.155.10
DomainGFP-like

NID2 STAB2 STAB1

5.11e-0611603IPR023413
DomainLaminin_EGF

CRELD1 STAB2 USH2A STAB1

6.55e-0638604IPR002049
DomainMAM_1

TMPRSS15 ZAN MAMDC4

1.71e-0516603PS00740
DomainCUB

SCUBE1 TMPRSS15 LRP3 MFRP

1.83e-0549604PF00431
DomainCUB

SCUBE1 TMPRSS15 LRP3 MFRP

1.98e-0550604SM00042
DomainMAM

TMPRSS15 ZAN MAMDC4

2.08e-0517603SM00137
Domain-

SCUBE1 TMPRSS15 LRP3 MFRP

2.32e-05526042.60.120.290
DomainMAM

TMPRSS15 ZAN MAMDC4

2.49e-0518603PF00629
DomainMAM_dom

TMPRSS15 ZAN MAMDC4

2.49e-0518603IPR000998
DomainMAM_2

TMPRSS15 ZAN MAMDC4

2.49e-0518603PS50060
DomainCUB

SCUBE1 TMPRSS15 LRP3 MFRP

2.50e-0553604PS01180
DomainCUB_dom

SCUBE1 TMPRSS15 LRP3 MFRP

3.35e-0557604IPR000859
DomainSRCR

TMPRSS15 TMPRSS3 HHIPL1

4.02e-0521603PF00530
DomainFAS1

STAB2 STAB1

6.06e-054602SM00554
DomainFAS1_domain

STAB2 STAB1

6.06e-054602IPR000782
Domain-

STAB2 STAB1

6.06e-0546022.30.180.10
DomainFAS1

STAB2 STAB1

6.06e-054602PS50213
DomainFasciclin

STAB2 STAB1

6.06e-054602PF02469
DomainSR

TMPRSS15 TMPRSS3 HHIPL1

6.89e-0525603SM00202
Domain-

TMPRSS15 TMPRSS3 HHIPL1

6.89e-05256033.10.250.10
DomainSRCR_1

TMPRSS15 TMPRSS3 HHIPL1

7.77e-0526603PS00420
DomainSRCR_2

TMPRSS15 TMPRSS3 HHIPL1

7.77e-0526603PS50287
DomainSRCR-like_dom

TMPRSS15 TMPRSS3 HHIPL1

7.77e-0526603IPR017448
DomainSRCR

TMPRSS15 TMPRSS3 HHIPL1

8.73e-0527603IPR001190
DomainhEGF

EYS FBN2 JAG1

9.75e-0528603PF12661
DomainNIDO_dom

NID2 TECTA

1.01e-045602IPR003886
DomainNIDO

NID2 TECTA

1.01e-045602SM00539
DomainNIDO

NID2 TECTA

1.01e-045602PF06119
DomainNIDO

NID2 TECTA

1.01e-045602PS51220
DomainYD

NID2 TENM4

1.01e-045602IPR006530
DomainEGF_LAM_2

STAB2 USH2A STAB1

1.20e-0430603PS50027
DomainEGF_LAM_1

STAB2 USH2A STAB1

1.20e-0430603PS01248
DomainPeptidase_S8_Asp-AS

PCSK1 PCSK2

1.51e-046602IPR023827
DomainLaminin_EGF

CRELD1 USH2A STAB1

1.92e-0435603PF00053
DomainEGF_Lam

STAB2 USH2A STAB1

1.92e-0435603SM00180
DomainPrprotnconvertsP

PCSK1 PCSK2

2.11e-047602IPR002884
DomainP_proprotein

PCSK1 PCSK2

2.11e-047602PF01483
DomainS8_pro-domain

PCSK1 PCSK2

2.11e-047602IPR032815
Domain-

PCSK1 PCSK2

2.11e-0476023.30.70.850
DomainS8_pro-domain

PCSK1 PCSK2

2.11e-047602PF16470
DomainSRCR_2

TMPRSS15 TMPRSS3

2.11e-047602PF15494
DomainVWFC_2

VWF ZAN TECTA

2.45e-0438603PS50184
DomainTRYPSIN_HIS

TMPRSS15 PRSS56 TMPRSS3 PRSS42P

3.36e-04103604IPR018114
DomainPeptidase_S8_His-AS

PCSK1 PCSK2

3.60e-049602IPR022398
DomainPeptidase_S8_Ser-AS

PCSK1 PCSK2

3.60e-049602IPR023828
DomainTRYPSIN_SER

TMPRSS15 PRSS56 TMPRSS3 PRSS42P

3.74e-04106604PS00135
DomainTRYPSIN_HIS

TMPRSS15 PRSS56 TMPRSS3 PRSS42P

3.88e-04107604PS00134
DomainPeptidase_S8_subtilisin-rel

PCSK1 PCSK2

4.49e-0410602IPR015500
DomainSUBTILASE_ASP

PCSK1 PCSK2

4.49e-0410602PS00136
DomainSUBTILASE_HIS

PCSK1 PCSK2

4.49e-0410602PS00137
DomainSUBTILASE_SER

PCSK1 PCSK2

4.49e-0410602PS00138
PathwayWP_FATTY_ACIDS_AND_LIPOPROTEINS_TRANSPORT_IN_HEPATOCYTES

VLDLR TMPRSS15 STAB2 TMPRSS3 LRP2 LRP3 LRP4 HHIPL1 LRP1B

2.15e-06381449M48063
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

NID2 SCUBE1 FBN2 VWF TNC LRP4 TNXB MUSK

3.49e-06300448M610
PathwayREACTOME_ECM_PROTEOGLYCANS

TNC LRP4 TNXB MUSK

8.99e-0576444M27219
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

NID2 SCUBE1 FBN2 VWF TNC TNXB

1.40e-04258446MM14572
PathwayWP_GLP1_FROM_INTESTINE_AND_PANCREAS_AND_ROLE_IN_GLUCOSE_HOMEOSTASIS

PCSK1 PCSK2

1.42e-046442M48303
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

CRELD1 NID2 FBN2 VWF TNC GPC4 TNXB

2.23e-0817560728071719
Pubmed

MESD is essential for apical localization of megalin/LRP2 in the visceral endoderm.

VLDLR LRP2 LRP4 LRP1B

4.68e-082160421337463
Pubmed

Interaction of the apolipoprotein E receptors low density lipoprotein receptor-related protein and sorLA/LR11.

LRP2 LRP3 LRP4

4.87e-08560319047013
Pubmed

Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.

CRELD1 NID2 FBN2 VWF TNC TNXB

1.29e-0713560628675934
Pubmed

Microfibril-associated glycoprotein-2 interacts with fibrillin-1 and fibrillin-2 suggesting a role for MAGP-2 in elastic fiber assembly.

FBN2 VWF JAG1

4.07e-07960312122015
Pubmed

Extracellular matrix protein composition dynamically changes during murine forelimb development.

NID2 FBN2 TNC

7.97e-071160338303699
Pubmed

LRP2 mediates folate uptake in the developing neural tube.

LRP2 LRP4 LRP1B

7.97e-071160324639464
Pubmed

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.

VLDLR GPR37L1 LRP2 LRP1B MUSK

8.99e-0710160523382219
Pubmed

Normal development and fertility of knockout mice lacking the tumor suppressor gene LRP1b suggest functional compensation by LRP1.

VLDLR LRP2 LRP1B

1.75e-061460315082773
Pubmed

The proprotein convertase PC2 is involved in the maturation of prosomatostatin to somatostatin-14 but not in the somatostatin deficit in Alzheimer's disease.

PCSK1 PCSK2

2.93e-06260214614908
Pubmed

Pathogenic variants of MFRP and PRSS56 genes are major causes of nanophthalmos in Japanese patients.

PRSS56 MFRP

2.93e-06260237501562
Pubmed

Abnormal expression and processing of the proprotein convertases PC1 and PC2 in human colorectal liver metastases.

PCSK1 PCSK2

2.93e-06260216293189
Pubmed

The tenascin gene family in axon growth and guidance.

TNC TNXB

2.93e-0626029321695
Pubmed

FEEL-1 and FEEL-2 are endocytic receptors for advanced glycation end products.

STAB2 STAB1

2.93e-06260212473645
Pubmed

Targeted high-resolution quadrupole-Orbitrap mass spectrometry analyses reveal a significant reduction of tachykinin and opioid neuropeptides level in PC1 and PC2 mutant mouse spinal cords.

PCSK1 PCSK2

2.93e-06260228476408
Pubmed

Identifying Stabilin-1 and Stabilin-2 Double Knockouts in Reproduction and Placentation: A Descriptive Study.

STAB2 STAB1

2.93e-06260233008099
Pubmed

Novel mutations in MFRP and PRSS56 are associated with posterior microphthalmos.

PRSS56 MFRP

2.93e-06260232118495
Pubmed

Developmental expression of the prohormone convertases PC1 and PC2 in mouse pancreatic islets.

PCSK1 PCSK2

2.93e-0626027925129
Pubmed

Exploring the transcriptomic network of multi-ligand scavenger receptor Stabilin-1- and Stabilin-2-deficient liver sinusoidal endothelial cells.

STAB2 STAB1

2.93e-06260233130055
Pubmed

Tachykinins Processing is Significantly Impaired in PC1 and PC2 Mutant Mouse Spinal Cord S9 Fractions.

PCSK1 PCSK2

2.93e-06260226373413
Pubmed

Decreased hypothalamic prohormone convertase expression in huntington disease patients.

PCSK1 PCSK2

2.93e-06260224226266
Pubmed

Endocrinomic profile of neurointermediate lobe pituitary prohormone processing in PC1/3- and PC2-Null mice using SELDI-TOF mass spectrometry.

PCSK1 PCSK2

2.93e-06260215956344
Pubmed

Biosynthesis of proTRH-derived peptides in prohormone convertase 1 and 2 knockout mice.

PCSK1 PCSK2

2.93e-06260222421509
Pubmed

cDNA sequence of two distinct pituitary proteins homologous to Kex2 and furin gene products: tissue-specific mRNAs encoding candidates for pro-hormone processing proteinases.

PCSK1 PCSK2

2.93e-0626022264933
Pubmed

Tenascin-X expression in tumor cells and fibroblasts: glucocorticoids as negative regulators in fibroblasts.

TNC TNXB

2.93e-0626028856503
Pubmed

The majority of autosomal recessive nanophthalmos and posterior microphthalmia can be attributed to biallelic sequence and structural variants in MFRP and PRSS56.

PRSS56 MFRP

2.93e-06260231992737
Pubmed

Neuronal LRP4 regulates synapse formation in the developing CNS.

LRP4 MUSK

2.93e-06260229061639
Pubmed

Immunohistochemical expressions of prohormone convertase (PC)1/3 and PC2 in carcinoids of various organs.

PCSK1 PCSK2

2.93e-06260210530621
Pubmed

Analysis of peptides in prohormone convertase 1/3 null mouse brain using quantitative peptidomics.

PCSK1 PCSK2

2.93e-06260220412386
Pubmed

Mechanism for phosphatidylserine-dependent erythrophagocytosis in mouse liver.

STAB2 STAB1

2.93e-06260221427291
Pubmed

Diagnostic and clinical classification of autoimmune myasthenia gravis.

LRP4 MUSK

2.93e-06260224530233
Pubmed

Identification of a cDNA encoding a second putative prohormone convertase related to PC2 in AtT20 cells and islets of Langerhans.

PCSK1 PCSK2

2.93e-0626021988934
Pubmed

Deficiency of liver sinusoidal scavenger receptors stabilin-1 and -2 in mice causes glomerulofibrotic nephropathy via impaired hepatic clearance of noxious blood factors.

STAB2 STAB1

2.93e-06260221293057
Pubmed

Comparative biosynthesis, covalent post-translational modifications and efficiency of prosegment cleavage of the prohormone convertases PC1 and PC2: glycosylation, sulphation and identification of the intracellular site of prosegment cleavage of PC1 and PC2.

PCSK1 PCSK2

2.93e-0626028397508
Pubmed

Revisiting Proinsulin Processing: Evidence That Human β-Cells Process Proinsulin With Prohormone Convertase (PC) 1/3 but Not PC2.

PCSK1 PCSK2

2.93e-06260232291281
Pubmed

Stabilin-1 and stabilin-2 are both directed into the early endocytic pathway in hepatic sinusoidal endothelium via interactions with clathrin/AP-2, independent of ligand binding.

STAB2 STAB1

2.93e-06260215572036
Pubmed

Phenotypical and biochemical characterization of murine psoriasiform and fibrotic skin disease models in Stabilin-deficient mice.

STAB2 STAB1

2.93e-06260238946049
Pubmed

Cloning and primary sequence of a mouse candidate prohormone convertase PC1 homologous to PC2, Furin, and Kex2: distinct chromosomal localization and messenger RNA distribution in brain and pituitary compared to PC2.

PCSK1 PCSK2

2.93e-0626022017186
Pubmed

A survey of the mouse hindbrain in the fed and fasted states using single-nucleus RNA sequencing.

PCSK1 PCSK2

2.93e-06260233962048
Pubmed

The role of agrin, Lrp4 and MuSK during dendritic arborization and synaptogenesis in cultured embryonic CNS neurons.

LRP4 MUSK

2.93e-06260230385274
Pubmed

Stabilin-1 and -2 constitute a novel family of fasciclin-like hyaluronan receptor homologues.

STAB2 STAB1

2.93e-06260211829752
Pubmed

Invasion of melanoma in double knockout mice lacking tenascin-X and tenascin-C.

TNC TNXB

2.93e-06260212359049
Pubmed

Comparative tissue distribution of the processing enzymes "prohormone thiol protease," and prohormone convertases 1 and 2, in human PTHrP-producing cell lines and mammalian neuroendocrine tissues.

PCSK1 PCSK2

2.93e-06260211720250
Pubmed

Biometric and molecular characterization of clinically diagnosed posterior microphthalmos.

PRSS56 MFRP

2.93e-06260223127749
Pubmed

FEEL-1, a novel scavenger receptor with in vitro bacteria-binding and angiogenesis-modulating activities.

STAB2 STAB1

2.93e-06260212077138
Pubmed

Microarray-based identification of tenascin C and tenascin XB, genes possibly involved in tumorigenesis associated with neurofibromatosis type 1.

TNC TNXB

2.93e-06260217202312
Pubmed

Differences in pH optima and calcium requirements for maturation of the prohormone convertases PC2 and PC3 indicates different intracellular locations for these events.

PCSK1 PCSK2

2.93e-0626027836407
Pubmed

Fibrillin-2 and Tenascin-C bridge the age gap in lung epithelial regeneration.

FBN2 TNC

2.93e-06260228662401
Pubmed

Gene profiling of postnatal Mfrprd6 mutant eyes reveals differential accumulation of Prss56, visual cycle and phototransduction mRNAs.

PRSS56 MFRP

2.93e-06260225357075
Pubmed

The change in tenascin expression in mouse uterus during early pregnancy.

TNC TNXB

2.93e-0626029013311
Pubmed

Association of Differentially Altered Liver Fibrosis with Deposition of TGFBi in Stabilin-Deficient Mice.

STAB2 STAB1

2.93e-06260237446152
Pubmed

cDNA sequence of two distinct pituitary proteins homologous to Kex2 and furin gene products: tissue-specific mRNAs encoding candidates for pro-hormone processing proteinases.

PCSK1 PCSK2

2.93e-0626022169760
Pubmed

Distribution of tenascin-C and -X, and soft X-ray analysis of the mandibular symphysis during mandible formation in the human fetus.

TNC TNXB

2.93e-06260215455729
Pubmed

Tenascin variants: ligands and expression.

TNC TNXB

2.93e-0626027509489
Pubmed

The effects of tenascin C knockdown on trabecular meshwork outflow resistance.

TNC TNXB

2.93e-06260223882691
Pubmed

Scavenging Endothelium of Pancreatic Islets: Differential Expression of Stabilin-1 and Stabilin-2 in Mice and Humans.

STAB2 STAB1

2.93e-06260227977633
Pubmed

MuSK IgG4 autoantibodies cause myasthenia gravis by inhibiting binding between MuSK and Lrp4.

LRP4 MUSK

2.93e-06260224297891
Pubmed

Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

FCGBP TNC AFM ADGRF5 C9 TNXB

5.50e-0625760616335952
Pubmed

UBE2S interacting with TRIM21 mediates the K11-linked ubiquitination of LPP to promote the lymphatic metastasis of bladder cancer.

RANBP2 LPP HERC2

6.35e-062160337422473
Pubmed

Genome-wide association study in Chinese identifies novel loci for blood pressure and hypertension.

JAG1 TNXB CASZ1

6.35e-062160325249183
Pubmed

Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.

FBN2 TENM4 LRP2 MUC6

7.13e-067160433541421
Pubmed

Expression of tenascin in developing and adult mouse lymphoid organs.

TNC TNXB

8.77e-0636027687262
Pubmed

Highly oxidized albumin is cleared by liver sinusoidal endothelial cells via the receptors stabilin-1 and -2.

STAB2 STAB1

8.77e-06360237926735
Pubmed

Disruption of proprotein convertase 1/3 (PC1/3) expression in mice causes innate immune defects and uncontrolled cytokine secretion.

PCSK1 PCSK2

8.77e-06360222396549
Pubmed

The tenascin gene family.

TNC TNXB

8.77e-0636027530141
Pubmed

Altered processing of the neurotensin/neuromedin N precursor in PC2 knock down mice: a biochemical and immunohistochemical study.

PCSK1 PCSK2

8.77e-06360212358783
Pubmed

Prohormone convertase 1/3 is essential for processing of the glucose-dependent insulinotropic polypeptide precursor.

PCSK1 PCSK2

8.77e-06360216476726
Pubmed

Tenascin-C, tenascin-R and tenascin-X: a family of talented proteins in search of functions.

TNC TNXB

8.77e-0636027694605
Pubmed

Differential processing of proenkephalin by prohormone convertases 1(3) and 2 and furin.

PCSK1 PCSK2

8.77e-0636028262946
Pubmed

MuSK myasthenia gravis IgG4 disrupts the interaction of LRP4 with MuSK but both IgG4 and IgG1-3 can disperse preformed agrin-independent AChR clusters.

LRP4 MUSK

8.77e-06360224244707
Pubmed

Detection of Clinically Relevant Genetic Variants in Chinese Patients With Nanophthalmos by Trio-Based Whole-Genome Sequencing Study.

PRSS56 MFRP

8.77e-06360231266062
Pubmed

Stabilin receptors clear LPS and control systemic inflammation.

STAB2 STAB1

8.77e-06360234816100
Pubmed

Agrin binds to the N-terminal region of Lrp4 protein and stimulates association between Lrp4 and the first immunoglobulin-like domain in muscle-specific kinase (MuSK).

LRP4 MUSK

8.77e-06360221969364
Pubmed

Chromosomal assignments of the genes for neuroendocrine convertase PC1 (NEC1) to human 5q15-21, neuroendocrine convertase PC2 (NEC2) to human 20p11.1-11.2, and furin (mouse 7[D1-E2] region).

PCSK1 PCSK2

8.77e-0636021765368
Pubmed

Prohormone convertases 1/3 and 2 together orchestrate the site-specific cleavages of progastrin to release gastrin-34 and gastrin-17.

PCSK1 PCSK2

8.77e-06360218554181
Pubmed

The endothelial cell receptor stabilin-2 regulates VWF-FVIII complex half-life and immunogenicity.

STAB2 VWF

8.77e-06360230124466
Pubmed

Processing of mouse proglucagon by recombinant prohormone convertase 1 and immunopurified prohormone convertase 2 in vitro.

PCSK1 PCSK2

8.77e-0636027730317
Pubmed

PC1/3, PC2 and PC5/6A are targeted to dense core secretory granules by a common mechanism.

PCSK1 PCSK2

8.77e-06360217645548
Pubmed

Tenascins and osteopontin in biological response in cornea.

TNC TNXB

8.77e-06360237209968
Pubmed

On the tissue-specific processing of procholecystokinin in the brain and gut--a short review.

PCSK1 PCSK2

8.77e-06360215075450
Pubmed

The dynamic expression of tenascin-C and tenascin-X during early heart development in the mouse.

TNC TNXB

8.77e-06360212823230
Pubmed

The cell-specific pattern of cholecystokinin peptides in endocrine cells versus neurons is governed by the expression of prohormone convertases 1/3, 2, and 5/6.

PCSK1 PCSK2

8.77e-06360218096669
Pubmed

Receptor tyrosine kinase specific for the skeletal muscle lineage: expression in embryonic muscle, at the neuromuscular junction, and after injury.

TNC MUSK

8.77e-0636027546737
Pubmed

Expression of PCSK1 (PC1/3), PCSK2 (PC2) and PCSK3 (furin) in mouse small intestine.

PCSK1 PCSK2

8.77e-06360218706454
Pubmed

Subtilisin-like proprotein convertase expression, localization, and activity in the human retina and optic nerve head.

PCSK1 PCSK2

8.77e-06360219339735
Pubmed

A switch from prohormone convertase (PC)-2 to PC1/3 expression in transplanted alpha-cells is accompanied by differential processing of proglucagon and improved glucose homeostasis in mice.

PCSK1 PCSK2

8.77e-06360217698597
Pubmed

Biological processing of the cocaine and amphetamine-regulated transcript precursors by prohormone convertases, PC2 and PC1/3.

PCSK1 PCSK2

8.77e-06360212584191
Pubmed

Novel TMEM98, MFRP, PRSS56 variants in a large United States high hyperopia and nanophthalmos cohort.

PRSS56 MFRP

8.77e-06360233203948
Pubmed

An islet amyloid peptide is derived from an 89-amino acid precursor by proteolytic processing.

PCSK1 PCSK2

8.77e-0636023053705
Pubmed

Chromosomal localization of human genes for the LDL receptor family member glycoprotein 330 (LRP2) and its associated protein RAP (LRPAP1).

LRP2 LRP3

8.77e-0636027959795
Pubmed

Role of beta-cell prohormone convertase (PC)1/3 in processing of pro-islet amyloid polypeptide.

PCSK1 PCSK2

8.77e-06360214693708
Pubmed

Comprehensive proteomic characterization of stem cell-derived extracellular matrices.

NID2 FBN2 TNC TNXB

1.53e-058660428327460
Pubmed

Proprotein and prohormone convertases: a family of subtilases generating diverse bioactive polypeptides.

PCSK1 PCSK2

1.75e-05460210701998
Pubmed

The collagen ColQ binds to LRP4 and regulates the activation of the Muscle-Specific Kinase-LRP4 receptor complex by agrin at the neuromuscular junction.

LRP4 MUSK

1.75e-05460237356721
Pubmed

On the processing of proghrelin to ghrelin.

PCSK1 PCSK2

1.75e-05460217050541
Pubmed

Synapse-specific Lrp4 mRNA enrichment requires Lrp4/MuSK signaling, muscle activity and Wnt non-canonical pathway.

LRP4 MUSK

1.75e-05460234090516
Pubmed

Production of n-octanoyl-modified ghrelin in cultured cells requires prohormone processing protease and ghrelin O-acyltransferase, as well as n-octanoic acid.

PCSK1 PCSK2

1.75e-05460219628676
Pubmed

The VWF/LRP4/αVβ3-axis represents a novel pathway regulating proliferation of human vascular smooth muscle cells.

VWF LRP4

1.75e-05460233576766
Pubmed

Targeting of Scavenger Receptors Stabilin-1 and Stabilin-2 Ameliorates Atherosclerosis by a Plasma Proteome Switch Mediating Monocyte/Macrophage Suppression.

STAB2 STAB1

1.75e-05460236325910
Pubmed

Deficiency for scavenger receptors Stabilin-1 and Stabilin-2 leads to age-dependent renal and hepatic depositions of fasciclin domain proteins TGFBI and Periostin in mice.

STAB2 STAB1

1.75e-05460237357460
InteractionZNF224 interactions

FBN2 LRP2 LRP4 LRP1B

3.32e-0720604int:ZNF224
InteractionNTN5 interactions

FBN2 LRP2 LRP4 LRP1B

7.21e-0724604int:NTN5
InteractionFEZF1 interactions

LRP2 LRP4 HERC2 LRP1B

1.38e-0628604int:FEZF1
InteractionIGFL3 interactions

VLDLR FBN2 LRP2 LRP4 LRP1B

2.90e-0675605int:IGFL3
InteractionZNF408 interactions

CRELD1 VLDLR FBN2 LRP2 LRP4 LRP1B

4.55e-06145606int:ZNF408
InteractionZFP41 interactions

FBN2 LRP2 LRP4 LRP1B

2.49e-0557604int:ZFP41
InteractionANKRD36B interactions

VLDLR LRP2 LRP4 LRP1B

3.06e-0560604int:ANKRD36B
InteractionST14 interactions

VLDLR FBN2 STC2 GPC4 GXYLT1 ADAM30

3.45e-05207606int:ST14
InteractionPMCH interactions

PCSK1 PCSK2 HERC2

6.21e-0526603int:PMCH
GeneFamilyLow density lipoprotein receptors

VLDLR LRP2 LRP3 LRP4 LRP1B

4.55e-1113395634
GeneFamilyProteases, serine

TMPRSS15 PRSS56 TMPRSS3 PRSS42P

1.00e-0563394738
GeneFamilyProprotein convertase subtilisin/kexin family

PCSK1 PCSK2

1.62e-049392973
GeneFamilyFibronectin type III domain containing

TNC OBSCN USH2A TNXB

3.82e-04160394555
GeneFamilyFibrinogen C domain containing

TNC TNXB

1.32e-0325392554
GeneFamilyADAM metallopeptidase domain containing|CD molecules

ADAM23 ADAM30

1.54e-032739247
GeneFamilyC2-set domain containing|Immunoglobulin like domain containing|Scavenger receptors

STAB2 STAB1

1.54e-03273921253
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

OBSCN ADGRF5 MUSK

5.01e-03161393593
CoexpressionNABA_ECM_GLYCOPROTEINS

CRELD1 NID2 EYS FBN2 VWF TNC TECTA USH2A TNXB

6.47e-10196609M3008
CoexpressionNABA_MATRISOME

CRELD1 NID2 EYS SCUBE1 TMPRSS15 FBN2 VWF ADAM23 TNC GPC4 ADAM30 TECTA USH2A TNXB MUC6

7.16e-0910266015M5889
CoexpressionNABA_CORE_MATRISOME

CRELD1 NID2 EYS FBN2 VWF TNC TECTA USH2A TNXB

1.25e-08275609M5884
CoexpressionNABA_MATRISOME

CRELD1 NID2 SCUBE1 TMPRSS15 FBN2 VWF ADAM23 TNC GPC4 ADAM30 TECTA MFRP TNXB MUC6

4.71e-0810086014MM17056
CoexpressionNABA_ECM_GLYCOPROTEINS

CRELD1 NID2 FBN2 VWF TNC TECTA TNXB

2.72e-07191607MM17059
CoexpressionNABA_CORE_MATRISOME

CRELD1 NID2 FBN2 VWF TNC TECTA TNXB

2.76e-06270607MM17057
CoexpressionPILON_KLF1_TARGETS_UP

MKRN4P NID2 STAB2 FBN2 VWF AFM LPP HERC4

3.12e-05541608MM1061
CoexpressionSIMBULAN_UV_RESPONSE_NORMAL_DN

CCNF PIP4K2B MN1

5.92e-0533603M16114
CoexpressionHALLMARK_PANCREAS_BETA_CELLS

PCSK1 PCSK2 ELP4

1.06e-0440603M5957
CoexpressionTRAVAGLINI_LUNG_PERICYTE_CELL

GPC4 OBSCN PERP ADGRF5

1.37e-04114604M41678
CoexpressionPILON_KLF1_TARGETS_UP

NID2 STAB2 FBN2 VWF AFM LPP HERC4

1.47e-04503607M2226
CoexpressionAtlaskidney_P3_CapMes_Crym_top-relative-expression-ranked_200

FBN2 TENM4 ADAM23 TNC JAG1 LRP4

5.44e-06166576gudmap_kidney_P3_CapMes_Crym_200
CoexpressionAtlaskidney_P0_JuxtaGlom_Ren1_top-relative-expression-ranked_500

CD93 PCSK2 VLDLR JAG1 LPP GPC4 LRP2 ADGRF5

2.79e-05456578gudmap_kidney_P0_JuxtaGlom_Ren1_500
CoexpressionAtlaskidney_P3_CapMes_Crym_k-means-cluster#4_top-relative-expression-ranked_200

FBN2 TENM4 JAG1 LRP4

2.80e-0565574gudmap_kidney_P3_CapMes_Crym_k4_200
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_1000

SCUBE1 FBN2 TENM4 STC2 TNC JAG1 RXFP2 GPC4 GXYLT1 TGS1

3.34e-057685710gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_1000
CoexpressionAtlasDevelopingKidney_e15.5_Endothelial cells_emap-29977_k-means-cluster#3_top-relative-expression-ranked_200

CD93 STAB2 ADGRF5 STAB1

6.03e-0579574DevelopingKidney_e15.5_Endothelial cells_emap-29977_k3_200
CoexpressionAtlaskidney_P4_CapMesRenVes_Crym_k-means-cluster#3_top-relative-expression-ranked_500

NID2 FBN2 TENM4 JAG1 LRP4

8.05e-05165575gudmap_kidney_P4_CapMesRenVes_Crym_k3_500
CoexpressionAtlasDevelopingKidney_e15.5_Endothelial cells_emap-29965_k-means-cluster#4_top-relative-expression-ranked_200

CD93 STAB2 ADGRF5 STAB1

8.41e-0586574gudmap_developingKidney_e15.5_Endothelial cells_200_k4
CoexpressionAtlaskidney_P4_CapMesRenVes_Crym_top-relative-expression-ranked_500

NID2 VLDLR FBN2 TENM4 JAG1 LRP2 LRP4

9.09e-05398577gudmap_kidney_P4_CapMesRenVes_Crym_500
CoexpressionAtlasDevelopingKidney_e15.5_early proxim tubul_emap-28005_k-means-cluster#4_top-relative-expression-ranked_1000

VLDLR AFM GPC4 PERP LRP2

1.01e-04173575gudmap_developingKidney_e15.5_early proxim tubul_1000_k4
CoexpressionAtlasStromal Cells, LEC.MLN, gp38+ CD31+, Lymph Node, avg-4

STAB2 TNC ADGRF5 STAB1

1.05e-0491574GSM777059_100
CoexpressionAtlasStromal Cells, LEC.SLN, gp38+ CD31+, Lymph Node, avg-4

STAB2 TNC ADGRF5 STAB1

1.29e-0496574GSM777063_100
CoexpressionAtlaskidney_P0_JuxtaGlom_Ren1_top-relative-expression-ranked_1000

CD93 PCSK2 VLDLR ADAM23 AFM JAG1 LPP GPC4 LRP2 ADGRF5

1.31e-049055710gudmap_kidney_P0_JuxtaGlom_Ren1_1000
CoexpressionAtlasJC_hmvEC_top-relative-expression-ranked_100

CD93 VWF ADGRF5 STAB1

1.45e-0499574JC_hmvEC_100
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_reference_CardioEndothel_top-relative-expression-ranked_100

CD93 VWF ADGRF5 STAB1

1.45e-0499574PCBC_ctl_CardioEndothel_100
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_reference_PulmonMicrovasc_top-relative-expression-ranked_100

CD93 VWF ADGRF5 STAB1

1.45e-0499574PCBC_ctl_PulmonMicrovasc_100
CoexpressionAtlasStromal Cells, LEC.MLN, gp38+ CD31+, Lymph Node, avg-4

CD93 NID2 STAB2 TNC JAG1 ADGRF5 STAB1

1.67e-04439577GSM777059_500
CoexpressionAtlasDevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_k-means-cluster#1_top-relative-expression-ranked_100

VLDLR AFM

1.96e-048572gudmap_developingKidney_e15.5_ureter tip_flank cortic collct_100_k1
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_1000

SCUBE1 FBN2 TENM4 STC2 ADAM23 JAG1 RXFP2 GPC4 GXYLT1

2.01e-04773579gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_1000
CoexpressionAtlaskidney_P4_CapMesRenVes_Crym_top-relative-expression-ranked_1000

NID2 VLDLR FBN2 TENM4 STC2 TNC JAG1 LRP2 LRP4

2.21e-04783579gudmap_kidney_P4_CapMesRenVes_Crym_1000
CoexpressionAtlasEndoderm Differentiated Cells_vs_Pluripotent Stem Cells-Confounder_removed-fold2.0_adjp0.05

CRELD1 VLDLR FBN2 VWF TENM4 TNC PERP C9

2.24e-04615578PCBC_ratio_DE_vs_SC_cfr-2X-p05
CoexpressionAtlasDevelopingKidney_e15.5_Endothelial cells_emap-29977_k-means-cluster#3_top-relative-expression-ranked_100

STAB2 ADGRF5 STAB1

2.56e-0446573DevelopingKidney_e15.5_Endothelial cells_emap-29977_k3_100
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#1_top-relative-expression-ranked_1000

SCUBE1 FBN2 TENM4 TNC GXYLT1 TGS1

2.81e-04337576gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k1_1000
CoexpressionAtlasDevelopingKidney_e15.5_Endothelial cells_emap-29965_k-means-cluster#4_top-relative-expression-ranked_500

CD93 STAB2 VWF ADGRF5 STAB1

2.89e-04217575gudmap_developingKidney_e15.5_Endothelial cells_500_k4
CoexpressionAtlasgeo_heart_top-relative-expression-ranked_500_k-means-cluster#1

VWF ADGRF5 STAB1

3.10e-0449573geo_heart_500_K1
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_1000

SCUBE1 FBN2 TENM4 STC2 TNC GPC4 GXYLT1 ADGRF5 TGS1

3.31e-04827579gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_1000
CoexpressionAtlaskidney_P3_CapMes_Crym_top-relative-expression-ranked_500

FBN2 TENM4 ADAM23 TNC JAG1 LRP4

4.61e-04370576gudmap_kidney_P3_CapMes_Crym_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#3_top-relative-expression-ranked_1000

TENM4 ADAM23 TNC PIP4K2B MN1

4.86e-04243575gudmap_developingLowerUrinaryTract_e14.5_ urethra_1000_k3
CoexpressionAtlasdev gonad_e11.5_M_ReproVasc_Flk_k-means-cluster#3_top-relative-expression-ranked_100

CD93 ADGRF5

6.31e-0414572gudmap_dev gonad_e11.5_M_ReproVasc_Flk_k3_100
CoexpressionAtlasDevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_k-means-cluster#1_top-relative-expression-ranked_200

VLDLR AFM

6.31e-0414572gudmap_developingKidney_e15.5_ureter tip_flank cortic collct_200_k1
CoexpressionAtlaskidney_P3_CapMes_Crym_k-means-cluster#2_top-relative-expression-ranked_500

FBN2 TENM4 JAG1 LRP4

6.72e-04148574gudmap_kidney_P3_CapMes_Crym_k2_500
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMPRSS15 STAB2 FBN2 TENM4 ZAN OBSCN LRP2 USH2A LRP1B

3.25e-121846092cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMPRSS15 STAB2 FBN2 TENM4 ZAN OBSCN LRP2 USH2A LRP1B

3.25e-12184609ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMPRSS15 STAB2 FBN2 TENM4 ZAN OBSCN LRP2 USH2A LRP1B

3.25e-121846092b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NID2 VLDLR TENM4 STC2 TNC JAG1 MN1

9.11e-091986079541d68a1a6247dbd7161a62644eea6527c2c8ff
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN2 RXFP2 LRP2 TECTA USH2A LRP1B

7.86e-08160606c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN2 RXFP2 LRP2 TECTA USH2A LRP1B

7.86e-0816060625c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellCOVID-19-kidney-Mito-rich_EC|kidney / Disease (COVID-19 only), tissue and cell type

CD93 VWF STC2 ADGRF5 MN1 TNXB

1.74e-071836063c4153479fc4ab2d073d92cee120480015555914
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCUBE1 STAB2 ADAM23 ADGRF5 TNXB STAB1

2.38e-071936062483bb7f398e4fa0ef09c8bd584ed25703853f03
ToppCellCOVID-19-kidney-PLVAP+EC|kidney / Disease (COVID-19 only), tissue and cell type

CD93 SCUBE1 VWF STC2 ADGRF5 STAB1

2.53e-07195606a436483fec137584611f86b7a498a4dc2aa19cd3
ToppCellCOVID-19-kidney-VWF+PLVAP+VCAM1+EC|kidney / Disease (COVID-19 only), tissue and cell type

CD93 VWF ADGRF5 MN1 TNXB STAB1

2.61e-07196606ac2c4a325efa8497a755cd31fb6a9d94d8e3bf42
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CD93 SCUBE1 VWF ADGRF5 TNXB STAB1

2.61e-0719660695c5b8fd4ebfae1f42de9b1475c1161d4a80e515
ToppCellASK454-Endothelial-Endothelium|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

CD93 VWF STC2 ADGRF5 TNXB CASZ1

2.61e-071966062b777a2026b56839112fd179f2db482c49f4594a
ToppCellLPS_only-Mesenchymal_myocytic-Myofibroblastic|LPS_only / Treatment groups by lineage, cell group, cell type

TNC LPP GPC4 LRP3 LRP4 TNXB

2.93e-0720060602cae2c296a13ad4cbb53bca7a86d64629d67d66
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB2 FBN2 ADAM23 ADGRF5 STAB1

2.13e-061556058fdda4e3657ac56188ae88ed3caf145f4d9d1567
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PCSK1 ZAN TECTA USH2A LRP1B

2.65e-06162605bf886e22ff2a20353499004b53f25fb9e6574896
ToppCelldroplet-Liver-Npc-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD93 STAB2 ADAM23 ADGRF5 STAB1

3.55e-06172605a6fb1bde8d942c7b5caaf7bd14de0b7ce32fda55
ToppCellfacs-Heart-RA-24m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD93 VWF PERP ADGRF5 STAB1

3.75e-0617460542dfb6f42b72e40e203b3ef341117bccf3553d54
ToppCellfacs-Heart-RA-24m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD93 VWF PERP ADGRF5 STAB1

3.75e-06174605f04edf2ca6788875c9918611e416fb739924382e
ToppCellfacs-Marrow-B-cells-24m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK2 LRP2 USH2A LRP1B FCAMR

3.86e-06175605887e75fc90e59a6394d62f3c048a9cfdf6707725
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK2 LRP2 USH2A LRP1B FCAMR

3.97e-06176605c6484334187f64cd00cd35e77d8ae436556b4260
ToppCelldroplet-Liver-Npc-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD93 STAB2 ADAM23 ADGRF5 STAB1

3.97e-061766053494ffa8555e6edf4b1250e10434bae9b73ec845
ToppCelldroplet-Liver-Npc-18m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD93 STAB2 ADAM23 ADGRF5 STAB1

3.97e-06176605d43f6b7828b98e1dab7b726a5f99499d65a7db80
ToppCellEndothelial|World / shred by cell class for turbinate

CD93 VWF STC2 ADGRF5 TNXB

4.31e-06179605052b2681974be00efb8503fa4e2c85d91d5ebd06
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCNF CD93 SCUBE1 VWF TNXB

4.43e-0618060540d4838a0ccb10d5e49266bc8a0037d27b75ccc2
ToppCellPCW_05-06-Endothelial-Endothelial_mature-endo_arterial_(9)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

CD93 EYS VWF ADGRF5 STAB1

4.43e-061806055861b44acfb8fe92c281c8355bf19c059b3dcd64
ToppCelldroplet-Mammary_Gland-nan-18m-Endothelial-nan|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD93 STAB2 VWF ADGRF5 STAB1

4.55e-061816052e15c46e8260bb04d8264478c19a707221996026
ToppCellCOVID-19-Heart-Fib_+_EC_+_Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

NID2 VWF TENM4 TNC TNXB

4.68e-06182605fbd5e332df73bf7141c822fa67b76367dc962017
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TENM4 TNC GPC4 LRP4 TNXB

4.80e-0618360512daaea821e49bc94a01e2496331e92a80d27339
ToppCellPND07-28-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_C|PND07-28-samps / Age Group, Lineage, Cell class and subclass

FBN2 TENM4 TNC LPP GPC4

5.06e-06185605427176ad9ab8d9511200fb0a132cfd1e835fe35c
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD93 VWF JAG1 ADGRF5 MN1

5.06e-06185605f98af3146ec2f44c30d31a662fb9c4fa3ca4f706
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TENM4 TNC GPC4 LRP4 TNXB

5.06e-061856053b2dfc8f4c87be516265dbecfc251276034d0efd
ToppCellPCW_05-06-Endothelial-Endothelial_mature-lymphatic|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

CD93 STAB2 VWF ADGRF5 STAB1

5.20e-0618660586b218a400f9c64f92b050f00b49f09647b17437
ToppCelldroplet-Lung-3m-Endothelial-arterial_endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD93 VWF JAG1 ADGRF5 STAB1

5.20e-06186605b80aaeebc03a318052076d2f02c123f5ddc5e73a
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CD93 TENM4 USH2A LRP1B STAB1

5.20e-0618660523b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCelldroplet-Lung-3m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD93 VWF JAG1 ADGRF5 STAB1

5.20e-061866058a8ed1502542d4895cba3fd5d534256206578716
ToppCellPCW_05-06-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

CD93 STAB2 VWF ADGRF5 STAB1

5.20e-06186605f51c76b1c3c6c49e0ebc9a913d8413e0b6a04d80
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial-GRIA2+_arterial_endo|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CD93 EYS VWF JAG1 ADGRF5

5.47e-06188605366a2d59b9c81d8a7659749f9c07efa46b49a39a
ToppCelldroplet-Kidney-nan-21m-Endothelial-kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD93 JAG1 OBSCN ADGRF5 MN1

5.62e-061896052ce330d8078833c05775c481e73770f9ee4a5c88
ToppCelldroplet-Kidney-nan-21m-Endothelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD93 JAG1 OBSCN ADGRF5 MN1

5.62e-06189605473c87036e04a058b4a5138438b7ba7e1e766799
ToppCell3'-Distal_airway-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CD93 VWF STC2 ADAM23 JAG1

5.62e-06189605e002dbb2138a6264be23f3b8148275a0cef351ef
ToppCellPND01-Endothelial-Endothelial_blood-vessel-Macrovascular_EC|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD93 VWF JAG1 ADGRF5 CASZ1

5.62e-061896051e1afa66b32ae752c0a42b02b80f10205464569c
ToppCelldroplet-Lung-3m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD93 VWF JAG1 ADGRF5 STAB1

5.62e-061896052e43428f1ef9683c6f8c9897d46aa7d34bf9047f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CD93 VWF JAG1 ADGRF5 MN1

5.76e-06190605bf9bc57a605c7e3979bc4f7260e6fb92c3eb8690
ToppCellControl-Endothelial-VE_Capillary_B|Endothelial / Disease state, Lineage and Cell class

CD93 VWF STC2 ADGRF5 CASZ1

5.76e-061906057f3f419fffe02934b6f27b697f7a6401072491ed
ToppCellfacs-Lung-3m-Endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD93 VWF ADGRF5 CASZ1 STAB1

5.76e-06190605d55b3ad4d1ec172b042bc08127506c354f87f69d
ToppCell21-Trachea-Endothelial|Trachea / Age, Tissue, Lineage and Cell class

CD93 STAB2 VWF ADGRF5 STAB1

5.76e-06190605bce09634acbc2cfd53666328e8aed8bf8835f845
ToppCelldroplet-Lung-21m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NID2 STAB2 STC2 TNC STAB1

5.76e-06190605f50b9814a1beac67dc042a8c27dfd085ceeda3a6
ToppCelldroplet-Lung-21m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NID2 STAB2 STC2 TNC STAB1

5.76e-06190605a22a510b4a257eb0eaf09c7ae7978d3d2f07a58c
ToppCelldroplet-Lung-21m-Endothelial-lymphatic_endothelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NID2 STAB2 STC2 TNC STAB1

5.76e-0619060557c136bf6d7feafb4a220877bed0cc8fdf314db2
ToppCell21-Trachea-Endothelial-Endothelial|Trachea / Age, Tissue, Lineage and Cell class

CD93 STAB2 VWF ADGRF5 STAB1

5.76e-0619060508437396a98ca9526f69c3a74bbf2929f3c68b8e
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD93 STAB2 ADAM23 ADGRF5 STAB1

5.91e-061916051924af7d8b0a0b892e480a9fd6d874941b0c0b5d
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD93 STAB2 ADAM23 ADGRF5 STAB1

5.91e-0619160588f91e57a1409bdeb91e9bf47510a6fb998a1bf5
ToppCellfacs-Liver-Non-hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD93 STAB2 ADAM23 ADGRF5 STAB1

6.06e-061926052bfac6b3956265205ca47d06888851ed68b65999
ToppCelldroplet-Pancreas-Exocrine-18m-Endothelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD93 NID2 ADGRF5 TNXB STAB1

6.06e-06192605a42aed9e563f5f4af029b8804c104f11ad227a8f
ToppCellCOVID-19-Heart-Fib_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

NID2 VWF TENM4 TNC TNXB

6.06e-0619260560b1312e84f6d6448365a952469c506c00b5fe93
ToppCelldroplet-Liver-HEPATOCYTES-1m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD93 STAB2 ADAM23 ADGRF5 STAB1

6.06e-061926055890076929598e88fe9d59a4e4e858b446746ce9
ToppCellfacs-Liver-Non-hepatocytes-24m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD93 STAB2 ADAM23 ADGRF5 STAB1

6.06e-06192605d525f7f088a53110912600a7c9f6d33b9270d534
ToppCelldroplet-Liver-HEPATOCYTES-1m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD93 STAB2 ADAM23 ADGRF5 STAB1

6.22e-061936054a8c97ff2dffc5c06351d1cb107e21e58250aa55
ToppCelldroplet-Liver-HEPATOCYTES-1m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD93 STAB2 ADAM23 ADGRF5 STAB1

6.22e-06193605d5f6d6e2c36d4e80af4d39cdfc0b18df295a587b
ToppCelldroplet-Lung-3m-Endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD93 VWF ADGRF5 CASZ1 STAB1

6.22e-0619360595c9c63bddfed1a84393ccd3578cfe65bc0c1c05
ToppCellfacs-Liver-Non-hepatocytes-3m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD93 STAB2 ADAM23 ADGRF5 STAB1

6.22e-061936058084fa0ce61f1f4a728423b6b81df04eaa5af5b6
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CD93 VWF JAG1 ADGRF5 MN1

6.22e-061936050b328f725f6feba263783eaca60c142e80df90f3
ToppCellfacs-Liver-Non-hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD93 STAB2 ADAM23 ADGRF5 STAB1

6.38e-06194605c8b9551b93a5aed62154b487db90130604a6125c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CD93 VWF JAG1 ADGRF5 MN1

6.38e-06194605b0c15e7e4bcf30856fb628dedd7ba82df33489f5
ToppCelldroplet-Liver-LIVER-NPC-1m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD93 STAB2 ADAM23 ADGRF5 STAB1

6.54e-06195605f55ab1018a6cde7d517b53e6ce44c3f7bde485c4
ToppCelldroplet-Liver-LIVER-NPC-1m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD93 STAB2 ADAM23 ADGRF5 STAB1

6.54e-06195605ea1b00805391dca8be0883b635768b296369919a
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD93 STAB2 ADAM23 ADGRF5 STAB1

6.54e-0619560512ba6d95e42d06b1991b011043c0e3370a7b4131
ToppCelldroplet-Liver-LIVER-NPC-1m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD93 STAB2 ADAM23 ADGRF5 STAB1

6.54e-06195605126f46dd15dddcf5701144718bb8ba1ce84b2d1d
ToppCelldroplet-Liver-LIVER-NPC-1m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD93 STAB2 ADAM23 ADGRF5 STAB1

6.54e-0619560585df110f753f58ab017018c54ee454edb4428e29
ToppCellbackground-Endothelial_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

CD93 STAB2 VWF ADGRF5 STAB1

6.54e-06195605c7d60dabfc7cb310e002cab10003dadfcc34fe33
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CD93 VWF JAG1 ADGRF5 MN1

6.54e-0619560577e47d2e8b3eb7f7c9620369ccaf87581f923bdb
ToppCellTracheal-10x5prime-Endothelial-Endothelia_vascular-VE_capillary|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CD93 VWF STC2 ADGRF5 STAB1

6.70e-06196605f0b106078212be1d0938f545707a004a1e830857
ToppCellASK454-Endothelial|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

CD93 VWF STC2 TNXB CASZ1

6.70e-0619660514dd6956ef420b660be0baf52a66960e57d75d16
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD93 STAB2 ADAM23 ADGRF5 STAB1

6.70e-0619660581900dcc9451ff6606ec940c16b559d73247590e
ToppCelldroplet-Liver-LIVER-NPC-1m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD93 STAB2 ADAM23 ADGRF5 STAB1

6.70e-061966050dfa2dc1ec527d40005614c00ed0e5f3a566c2e2
ToppCelldroplet-Liver-LIVER-NPC|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD93 STAB2 ADAM23 ADGRF5 STAB1

6.70e-06196605a3513c91afdc2d363e1c57071ae2399f9b7e6263
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD93 STAB2 ADAM23 ADGRF5 STAB1

6.87e-06197605deefb492b5f0e6014144bd465c4a6ae4206e8739
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD93 STAB2 ADAM23 ADGRF5 STAB1

6.87e-06197605d584d0334ea97e3fa8c4cd869f5eeea2c7a1ed04
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CD93 VWF ADGRF5 MN1 TNXB

6.87e-06197605cd509e49bbdbf991cc5913960ff3ef275ad40628
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD93 STAB2 ADAM23 ADGRF5 STAB1

6.87e-06197605a6aaa6faea348291023f0bc4b0f83fbc67d91da6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CD93 VWF ADGRF5 MN1 TNXB

6.87e-061976050f467ef58f0c4dcc00b34b7b9639e03fb3ebe780
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD93 STAB2 ADAM23 ADGRF5 STAB1

6.87e-06197605412091994196a06c2779b4c2cfed84be889a5f8d
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FBN2 TENM4 TNC LPP GPC4

7.04e-061986050993d6895c0e4f360998ce35abea4ec3dd13e048
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FBN2 TENM4 TNC LPP GPC4

7.04e-06198605a699b365d3b6149f13f02b2e2ae9b6fdce761848
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary-EC_general_capillary_L.2.0.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CD93 VWF STC2 JAG1 ADGRF5

7.04e-0619860540c2171e79f578c9116d872c189f953dc61d052d
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TENM4 TNC JAG1 OBSCN PERP

7.04e-061986055374b0e98d669f36a0571d3c006c7bd5e3c8e87f
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD93 STAB2 ADAM23 ADGRF5 STAB1

7.04e-06198605f0f1816a0ed3ae8207442602f5cbe4de0382e4b3
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CD93 SCUBE1 VWF TNXB STAB1

7.04e-06198605259fbcc0f2ac281a3e4d693de45b986fe5e24841
ToppCellnormal_Lung-Fibroblasts-Smooth_muscle_cells|Fibroblasts / Location, Cell class and cell subclass

SCUBE1 TNC LPP GPC4 PERP

7.22e-06199605d65847ceb68a560798df3f73e6f838e7c3e38a1c
ToppCellkidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CD93 VWF JAG1 ADGRF5 TNXB

7.22e-06199605a3ec743b978ba8fdf1677b4971b5731f50ddd30f
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CD93 VWF ADGRF5 TNXB STAB1

7.22e-06199605da5a88749d859d535daa030d0974485906cc0ba7
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CD93 VWF ADGRF5 TNXB STAB1

7.22e-06199605f35e9c05d0a0339ff691b38564da7aad8e9218aa
ToppCellParenchymal-NucSeq-Stromal-Peri/Epineurial_-NAF_epineurial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NID2 VLDLR FBN2 TENM4 TNXB

7.22e-061996056f5ef959b51eccf1ffc2e5ddf0d83c62ca2257b2
ToppCell(02)_MMP9/10+|World / shred by cell type by condition

STC2 TNC JAG1 GPC4 MN1

7.22e-061996053f78eddeaa67d3b767aa38de765632166b09a4f0
ToppCellParenchymal-NucSeq-Stromal-Peri/Epineurial_|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NID2 VLDLR FBN2 TENM4 TNXB

7.22e-061996051aa99d21bf61b86df4a966dc47634044430aa39f
ToppCellParenchymal-10x5prime-Endothelial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CD93 VWF STC2 ADGRF5 TNXB

7.39e-062006050e648e9eb96c83a94505d07323785a7a40997eb0
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CD93 VWF ADGRF5 TNXB STAB1

7.39e-06200605b1be27d134a8633e3e7862c6a0d7be2001d387f0
ToppCellControl_saline-Mesenchymal_myocytic-Myofibroblastic|Control_saline / Treatment groups by lineage, cell group, cell type

TNC LPP GPC4 LRP4 TNXB

7.39e-062006059d5b3c2dcfa55d50acc2ce2c319d51aa525d4cd1
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CD93 VWF JAG1 ADGRF5 TNXB

7.39e-0620060593e13937ec74418a697c37d56f57509fb2154780
ToppCellTracheal-10x5prime-Endothelial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CD93 VWF STC2 ADGRF5 STAB1

7.39e-0620060571ba0e48ca4ded077f2b96a0cf4f2331f2e25d15
Drugmonatepil

LRP2 LRP3 LRP4 LRP1B

9.85e-0729604CID000060810
Drugvitamin E

VLDLR EYS VWF AFM LRP2 LRP3 LRP4 LRP1B MUSK

2.18e-06441609CID000002116
Drugezetimibe

PCSK1 PCSK2 LRP2 LRP3 LRP4 LRP1B

2.46e-06147606CID000150311
DrugInsulin recombinant

PCSK1 PCSK2 LRP2

3.76e-0612603DB00030
DrugInsulin, porcine

PCSK1 PCSK2 LRP2

4.88e-0613603DB00071
Drugpyrachlostrobin

NID2 SCUBE1 TNC LPP GPC4 PERP LRP2 LRP4 REST MFRP STAB1

7.61e-068116011ctd:C513428
DrugAC1L9DEQ

JAG1 LPP

2.05e-053602CID000442786
DrugRgd Peptide

PCSK2 FBN2 VWF TNC TNXB TGS1

3.92e-05239606CID000104802
Drug3-ethylpyridine

TNC TNXB

4.08e-054602CID000010823
DrugAC1L1EPA

FBN2 JAG1

4.08e-054602CID000028140
Diseasefactor VIII measurement, venous thromboembolism

STAB2 VWF LRP4

4.57e-0534603EFO_0004286, EFO_0004630
Diseasehearing impairment

TMPRSS3 TECTA USH2A MN1

4.84e-0598604C1384666
Diseasetenascin measurement

TNC TNXB

1.81e-0410602EFO_0008296
Diseasecataract

JAG1 HERC2 LRP1B CASZ1

1.98e-04141604MONDO_0005129
DiseaseMicrophthalmos

PRSS56 MFRP

2.21e-0411602C0026010
Diseaseglaucoma

LPP HERC2 LRP1B ELP4

2.77e-04154604MONDO_0005041
Diseasephosphatidylcholine 40:7 measurement

ADAM23 MUSK

3.13e-0413602EFO_0021477
DiseaseProteinuria

VWF LRP2

4.20e-0415602HP_0000093
DiseaseNonsyndromic genetic hearing loss

TMPRSS3 REST TECTA

5.06e-0476603cv:C5680182
Diseaseintraocular pressure measurement

FBN2 LPP LRP4 HERC2 MFRP TNXB

5.82e-04509606EFO_0004695
DiseaseChild Behaviour Checklist assessment

PCSK2 TENM4

6.09e-0418602EFO_0005661
DiseaseNonsyndromic Deafness

TNC TMPRSS3 TECTA

6.09e-0481603C3711374
DiseaseHodgkins lymphoma

FCGBP LPP STAB1

6.31e-0482603EFO_0000183
Diseasepolycystic kidney disease (biomarker_via_orthology)

TNC C9

6.80e-0419602DOID:0080322 (biomarker_via_orthology)
Diseasefactor VIII measurement, Ischemic stroke

STAB2 VWF

6.80e-0419602EFO_0004630, HP_0002140
Diseaseage-related macular degeneration

REST HERC2 TNXB

8.02e-0489603EFO_0001365
Diseaseoptic disc size measurement

PRSS56 LRP2 LRP1B ELP4

8.14e-04205604EFO_0004832
Diseaseeye color

EYS AFM HERC2

8.28e-0490603EFO_0003949
Diseaseplatelet component distribution width

VWF ATP23 LPP ADGRF5 TNXB MUSK TGS1

8.31e-04755607EFO_0007984
Diseaseosteoarthritis, hip

TNC LPP HERC2

8.83e-0492603EFO_1000786
Diseasevenous thromboembolism, tissue plasminogen activator measurement

VWF LRP4

1.00e-0323602EFO_0004286, EFO_0004791
Diseaseeye colour measurement

CD93 LRP2 HERC2 USH2A

1.02e-03218604EFO_0009764
DiseaseMyasthenic Syndromes, Congenital

LRP4 MUSK

1.09e-0324602C0751882
DiseaseVitiligo

LPP HERC2 MUSK

1.16e-03101603EFO_0004208
Diseasecorpus collosum mid-posterior volume measurement

VLDLR JAG1

1.18e-0325602EFO_0010300
Diseaseprimary aldosteronism

RXFP2 CASZ1

1.28e-0326602MONDO_0001422
DiseaseL lactate dehydrogenase measurement

TENM4 STAB1

1.28e-0326602EFO_0004808
Diseasebirth weight

VLDLR TENM4 STC2 JAG1 USH2A

1.31e-03399605EFO_0004344
Diseasemonocyte count

VLDLR STAB2 JAG1 LPP ADGRF5 REST MN1 CASZ1 TGS1

1.32e-031320609EFO_0005091
Diseasedocosapentaenoic acid measurement

TNXB MUSK

1.38e-0327602EFO_0006809
Diseaseretinitis pigmentosa (implicated_via_orthology)

EYS USH2A

1.38e-0327602DOID:10584 (implicated_via_orthology)
Diseasefactor VIII measurement, von Willebrand factor measurement

STAB2 VWF

1.38e-0327602EFO_0004629, EFO_0004630
DiseaseMalignant neoplasm of breast

NID2 VWF STC2 JAG1 OBSCN HERC2 TECTA MAMDC4

1.43e-031074608C0006142
Diseasememory performance

EYS SCUBE1 LPP TMPRSS3 STAB1

1.46e-03409605EFO_0004874
DiseaseBilateral Wilms Tumor

GPC4 REST

1.59e-0329602C2930471
DiseaseAutosomal dominant nonsyndromic hearing loss

REST TECTA

1.59e-0329602cv:C5779548
Diseasefactor VIII measurement, coronary artery disease

STAB2 VWF HHIPL1

1.60e-03113603EFO_0001645, EFO_0004630
DiseaseJT interval

LPP OBSCN MUSK CASZ1

1.64e-03248604EFO_0007885
Diseasefactor XI measurement, venous thromboembolism

VWF LRP4

1.71e-0330602EFO_0004286, EFO_0004694
DiseaseIschemic stroke, von Willebrand factor measurement

STAB2 VWF

1.71e-0330602EFO_0004629, HP_0002140
Diseasevon Willebrand factor measurement, coronary artery disease

STAB2 VWF HHIPL1

1.81e-03118603EFO_0001645, EFO_0004629
Diseasesleep quality

FBN2 TENM4 LRP1B

1.81e-03118603EFO_0005272
Diseasemean arterial pressure, unipolar depression

PCNX3 CASZ1

1.94e-0332602EFO_0003761, EFO_0006340

Protein segments in the cluster

PeptideGeneStartEntry
CAGGEDEQACGTTDF

MAMDC4

481

Q6UXC1
EANCCDSAVDGTYNG

AKAP2

61

Q9Y2D5
GNGYVEAGEECDCGF

ADAM23

506

O75077
ATEDCGTADCQFYGQ

CASZ1

591

Q86V15
DVSSNYDGCCEGDVV

AFM

261

P43652
CEEGYVLAGEDGTQC

CD93

411

Q9NPY3
AYDGSGACGGSDACD

MKRN4P

66

Q13434
FCGVCSDTDEDNGNG

RANBP2

2736

P49792
DSVCDGFANCADGSD

MFRP

276

Q9BY79
FSCEDCNGNVSGGFD

ATP23

86

Q9Y6H3
GCVCAEGLYENADGQ

MUC6

806

Q6W4X9
GEVNGSCCDYLVGEE

REST

56

Q13127
CGADQFCVNTEGSYE

CRELD1

256

Q96HD1
NAYSEFECGNGECID

LRP1B

2511

Q9NZR2
GDGSDESPQCGYRQC

LRP1B

2831

Q9NZR2
GYRQCGTEEFSCADG

LRP1B

2841

Q9NZR2
NVGDCDGTACGYNTC

EYS

2891

Q5T1H1
DGTACGYNTCRNGGE

EYS

2896

Q5T1H1
QYSDFGCCDEGRDAE

HHIPL1

41

Q96JK4
EGSGSGCEYQQCPSE

GPC4

496

O75487
DDCGGGYSESIAEIC

HERC2

4476

O95714
CAGYEEGGIDSCQGD

TMPRSS15

956

P98073
GAGCNSGGNVDDSDC

PCNX3

1826

Q9H6A9
CSQEGGGSGSYEEGC

PERP

51

Q96FX8
DDGTVYTCGCNDLGQ

HERC4

51

Q5GLZ8
CIYGSNCQEAEEGGI

GXYLT1

346

Q4G148
DCGGLLSEGDNQGCY

LPP

571

Q93052
NTVDECGDGSDEGNC

LRP3

186

O75074
GQEDCQDGSDEHGCL

LRP3

476

O75074
DNDCGDGSDEKNCNS

LRP2

1131

P98164
QACQADTGEYSCEAG

OBSCN

1411

Q5VST9
GYQGDGRNCVDENEC

NID2

791

Q14112
GNECDLAEYCDGNSS

ADAM30

461

Q9UKF2
DDIGCYLCGIGSENN

FCAMR

146

Q8WWV6
CCSGYEGDQESEGEK

CCNF

611

P41002
EGCQCDSGFLYNGQA

FCGBP

3966

Q9Y6R7
CEECGGASEASAANG

GPR37L1

436

O60883
GDDICCAENGGNSHS

ELP4

266

Q96EB1
GGCDTQCTNSEGSYE

FBN2

1251

P35556
GSCDQGCVNTKGSYE

SCUBE1

371

Q8IWY4
DAEDDCGNDFQCSTG

C9

96

P02748
CAGYLAGGVDSCQGD

PRSS56

271

P0CW18
EATCNNGGTCYDEGD

JAG1

711

P78504
GAQNGDSELGSCCSE

MN1

1191

Q10571
SNDLECCGGEEGVVY

USH2A

3301

O75445
ECENDGVGGNLLCSY

PIP4K2B

306

P78356
CGNGADEENCGDTSG

RXFP2

71

Q8WXD0
SGCYVEEGDGDNVTC

ADGRF5

971

Q8IZF2
GSGEVCAVEDGYQGC

TECTA

691

O75443
CAGYLTGGVDSCQGD

TMPRSS3

386

P57727
TYGLCGICDENGAND

VWF

2081

P04275
GDVGCGVFECFENNS

STC2

61

O76061
ENGVCVCNAGYSGED

TNXB

446

P22105
INGTCYCEEGFTGED

TNC

326

P24821
DSCQGDSGGRLACEY

PRSS42P

261

Q7Z5A4
ESVDNCPSNCYGNGD

TENM4

561

Q6N022
KNDANCDCFSGDDGY

TENM4

1516

Q6N022
RAGNSCECSLGYEGD

STAB1

2071

Q9NY15
GFGGTACETCADDNL

STAB2

141

Q8WWQ8
GDQATEEEEGGYSCG

TGS1

56

Q96RS0
QGATFTCECEVGYGG

ZAN

2726

Q9Y493
FVCNGQDDCSDGSDE

VLDLR

171

P98155
EEGYCSQGCTNSEGA

LRP4

401

O75096
DSDDGIYCCTANNGV

MUSK

91

O15146
GRQGDNCDCDGYTDS

PCSK1

311

P29120
WASGDGGSYDDCNCD

PCSK2

306

P16519