Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessanterograde neuronal dense core vesicle transport

MAP2 KIF1B

5.70e-058302GO:1990048
GeneOntologyBiologicalProcessdense core granule cytoskeletal transport

MAP2 KIF1B

1.34e-0412302GO:0099519
GeneOntologyBiologicalProcessdense core granule transport

MAP2 KIF1B

1.84e-0414302GO:1901950
Domain-

OSBPL8 AKAP13 PTPN13 RASA3 KIF1B

2.16e-043912752.30.29.30
DomainPH

OSBPL8 AKAP13 RASA3 KIF1B

3.10e-04229274PF00169
DomainPH_dom-like

OSBPL8 AKAP13 PTPN13 RASA3 KIF1B

3.22e-04426275IPR011993
DomainPH

OSBPL8 AKAP13 RASA3 KIF1B

6.44e-04278274SM00233
DomainPH_DOMAIN

OSBPL8 AKAP13 RASA3 KIF1B

6.52e-04279274PS50003
DomainPH_domain

OSBPL8 AKAP13 RASA3 KIF1B

6.61e-04280274IPR001849
DomainTYR_PHOSPHATASE_1

PTPN13 DUSP29

6.83e-0386272PS00383
DomainTYR_PHOSPHATASE_2

PTPN13 DUSP29

6.98e-0387272PS50056
DomainTYR_PHOSPHATASE_dom

PTPN13 DUSP29

6.98e-0387272IPR000387
Domain-

PTPN13 DUSP29

7.78e-03922723.90.190.10
DomainProt-tyrosine_phosphatase-like

PTPN13 DUSP29

8.96e-0399272IPR029021
PathwayREACTOME_ERBB2_REGULATES_CELL_MOTILITY

DIAPH1 NRG3

1.63e-0413212MM15320
PathwayREACTOME_ERBB2_REGULATES_CELL_MOTILITY

DIAPH1 NRG3

2.19e-0415212M27608
Pubmed

Mutational analysis of FLASH and PTPN13 genes in colorectal carcinomas.

CASP8AP2 PTPN13

7.69e-07231218038312
Pubmed

Facilitation of dendritic mRNA transport by CPEB.

MAP2 KIF1B

4.61e-06431212629046
Pubmed

Single nucleotide polymorphism of TAG-1 influences IVIg responsiveness of Japanese patients with CIDP.

NRG3 KIF1B

2.15e-05831219776380
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

WRNIP1 DIAPH1 OSBPL8 AKAP13 FAM120A TUT7

4.03e-0573331634672954
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

OSBPL8 USP31 AKAP13 PTPN13 MAP2 KIF1B

9.81e-0586131636931259
Pubmed

CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI.

DIAPH1 AKAP13 PTPN13

1.10e-0410431331240132
Pubmed

Large-scale concatenation cDNA sequencing.

DIAPH1 FOXJ2 TRAPPC3 FAM120A HERC1

1.37e-045683159110174
Pubmed

A "double adaptor" method for improved shotgun library construction.

DIAPH1 FOXJ2 TRAPPC3 FAM120A HERC1

1.43e-045743158619474
Pubmed

The Rho-GTPase cdc42 regulates neural progenitor fate at the apical surface.

MAP2 F2RL2

2.10e-042431216892058
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

WRNIP1 OSBPL8 USP31 TRAPPC3 FAM120A MAP2 KIF1B

2.17e-04143131737142655
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

OSBPL8 USP31 CASP8AP2 AKAP13 PTPN13 FAM120A MAP2

2.74e-04148731733957083
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

AKAP13 PTPN13 FAM120A NRG3 MAP2 RASA3 KIF1B

2.77e-04148931728611215
Pubmed

LncRNAs-directed PTEN enzymatic switch governs epithelial-mesenchymal transition.

AKAP13 CCDC168 PTPN13

4.51e-0416831330631154
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

OSBPL8 USP31 PTPN13 RASA3

5.14e-0442131436976175
Pubmed

WD40-repeat 47, a microtubule-associated protein, is essential for brain development and autophagy.

HERC1 MAP2

5.87e-044031229078390
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

OSBPL8 AKAP13 RASA3 KIF1B

1.22e-04206234682
GeneFamilyZinc fingers MYND-type|A-kinase anchoring proteins

AKAP13 MAP2

6.15e-0429232396
GeneFamilyEndogenous ligands|Minor histocompatibility antigens

AKAP13 TRIM42

1.90e-0351232870
GeneFamilyOlfactory receptors, family 5

OR5AK3P OR5AK2

8.84e-03112232152
CoexpressionGSE3920_UNTREATED_VS_IFNA_TREATED_FIBROBLAST_UP

USP31 AKAP13 C1QTNF3 TRIM42 TUT7

1.07e-06168295M6704
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

OSBPL8 HERC1 NRG3 MAP2

9.12e-061983040ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCellLPS_only-Endothelial-Endothelial-FOXM1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAD1 RGS22 CENPI

9.89e-051343034d8f7ddad02fe76a614771e115ebb8e04623ba85
ToppCellPND01-03-samps-Mesenchymal-Pericyte|PND01-03-samps / Age Group, Lineage, Cell class and subclass

NOSTRIN DUSP29 MAP2

1.44e-04152303fc9472bc19f997103da535b035105f01429cb08e
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_vein-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NOSTRIN NRG3 C13orf42

1.86e-04166303f7926ee266dcbf10df375cd921f1db5a2fa604f8
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CASP8AP2 NOSTRIN NRG3

2.10e-04173303f193c63cc536d891c9d23043765e320252bb6e65
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DIAPH1 CASP8AP2 TUT7

2.29e-0417830301dafd19de04eff459253eaa9a35debf8f3deedf
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_vein-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NOSTRIN NRG3 MAP2

2.48e-04183303c1297d8eddfc7132e84ceef14f01b6281f9d0f6a
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

AKAP13 NRG3 RASA3

2.52e-04184303d2bf0135eb56bb410997dccea39c5ede88a0617f
ToppCellPCW_05-06-Endothelial-Endothelial_mature-endo_venous_(13)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

NOSTRIN NRG3 F2RL2

2.64e-0418730303de3c2df31bca0dc4e3718bada708d8fe8b69b9
ToppCellRV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

DIAPH1 AKAP13 DUSP29

2.72e-041893030a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCellLPS_only-Endothelial-Endothelial-Alv_Gen_Intermediate|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

USP31 NOSTRIN MAP2

2.72e-04189303e82211b9dc7540e7a183be2cbcfae39fdf503949
ToppCellRV-15._Ventricular_Cardiomyocyte_III|RV / Chamber and Cluster_Paper

DIAPH1 AKAP13 DUSP29

2.77e-0419030393c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCell(1)_T_cells-(1)_T_CD4_fh|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)

OSBPL8 AKAP13 PTPN13

2.77e-04190303120ca702600373c208a3d032fede0a040736e5cf
ToppCellRA-09._Endothelium_I|World / Chamber and Cluster_Paper

NOSTRIN NRG3 MAP2

2.81e-04191303c8a0c2af119bc34a8f694a7d30642f28002c84b9
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

AKAP13 MAP2 RASA3

2.85e-041923038b86db2ebe0199fee0e9800566a619a24bfdeed5
ToppCellRA-09._Endothelium_I|RA / Chamber and Cluster_Paper

NOSTRIN NRG3 MAP2

2.85e-041923038a1b1c3e83a68ad74f8f4eb00455c9e41aa57cfc
ToppCellPCW_13-14-Endothelial-Endothelial_immature-endo_immature4_(5)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

USP31 NOSTRIN NRG3

2.90e-0419330301c71aa48875b5ad6c50cc810a72862e72f26ad0
ToppCellPCW_13-14-Endothelial-Endothelial_mature-endo_venous_(13)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

NOSTRIN NRG3 C13orf42

2.90e-0419330384d1c1b7d3a1cb80f175527e3c89a2c3da7657f7
ToppCellPCW_13-14-Endothelial-Endothelial_mature-endo_capillary_(2)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

USP31 NOSTRIN NRG3

2.94e-041943033c31ac44e8cf4eca3ba7b8bfc05ad3e96a970956
ToppCellPCW_10-12-Endothelial-Endothelial_immature-endo_immature4_(5)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

USP31 NOSTRIN NRG3

2.94e-0419430353a5e8863d79a052dff0758f389be5ac3883c721
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM120A HERC1 KIF1B

2.99e-041953037796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellPCW_05-06-Endothelial-Endothelial_mature|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

NOSTRIN NRG3 F2RL2

2.99e-0419530354fde2cfa51ab3a2d48d2426494ca6f0ce77f725
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM120A HERC1 KIF1B

2.99e-041953033e519cffa6144a62b06124642a14c9ff39b76554
ToppCellControl-Lymphoid-T|Lymphoid / Disease state, Lineage and Cell class

OSBPL8 AKAP13 PTPN13

2.99e-041953036687e579582d7a239bee80846de0cf827a6f6a62
ToppCellPCW_10-12-Endothelial-Endothelial_immature|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

USP31 NOSTRIN NRG3

3.03e-04196303c65b8c7ea34a21897c390e6fb42ee8ca41e9c976
ToppCellPCW_13-14-Endothelial-Endothelial_immature|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

USP31 NOSTRIN NRG3

3.03e-041963039ed96085f0acce07bf2f8d4cc212cc50e613be0c
ToppCellPCW_10-12-Endothelial|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

USP31 NOSTRIN NRG3

3.03e-041963032c60dcf9132ee156f25b349e2ac5313709def4f6
ToppCellPCW_13-14-Endothelial|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

USP31 NOSTRIN NRG3

3.03e-041963037286de29a34e13834cd6347c67a1443897fa4ade
ToppCellFetal_29-31_weeks-Endothelial|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

USP31 NOSTRIN NRG3

3.03e-041963033981f6c7487598f4f7ce4650ac0ac5bd41481d66
ToppCellbackground-Endothelial_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

NOSTRIN HERC1 NRG3

3.03e-04196303e6fb0bfab1779ec64a8c35d01519eaafbf62e977
ToppCellPCW_10-12-Endothelial-Endothelial_immature-endo_immature1_(0)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

USP31 NOSTRIN NRG3

3.03e-0419630329ed8b1c4cd730db8632fde6eece404f1883a86d
ToppCellPCW_13-14-Endothelial-Endothelial_immature-endo_immature1_(0)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

USP31 NOSTRIN NRG3

3.08e-041973034e9221cb02122aed2981c3c9157e847a3710e323
ToppCellPCW_13-14-Endothelial-Endothelial_cycling-endo_proliferating3_(3)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

USP31 NOSTRIN NRG3

3.08e-04197303aedc1e3ed6b558bf2f7649919f43049f8348ab85
ToppCellPCW_13-14-Endothelial-Endothelial_cycling|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

USP31 NOSTRIN NRG3

3.12e-041983038fb624407abb9cb711d8d8a8665014cf6e39559a
ToppCellwk_20-22-Endothelial-Blood_vessel_endothelial-Venous_endo|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

NOSTRIN NRG3 MAP2

3.17e-0419930370e05d7c0c68c28754ce0e72434b205aed6287ae
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating-Cycling_Progenitors|1_mon / Sample Type, Dataset, Time_group, and Cell type.

WRNIP1 PTPN13 FAM120A

3.17e-04199303358c4b3037f59378db8916a2fbe9ed4830cf1449
ToppCellNeuronal|World / cells hierarchy compared to all cells using T-Statistic

HERC1 NRG3 MAP2

3.22e-0420030348d801219bc771d6c7e151dc88ca4c179988de85
Diseaseunipolar depression, smoking behaviour measurement

OR5AK3P OR5AK2

5.99e-064302EFO_0003761, EFO_0005671
Diseaseeye measurement

AKAP13 HERC1

3.45e-0427302EFO_0004731
Diseasechronic kidney disease, diabetic nephropathy

PTPN13 NRG3

6.16e-0436302EFO_0000401, EFO_0003884
Diseaseunipolar depression

USP31 CASP8AP2 OR5AK3P FAM120A OR5AK2 RASA3

1.18e-031206306EFO_0003761
Diseaseinterstitial lung disease

AKAP13 NRG3

2.12e-0367302EFO_0004244
Diseasemultiple sclerosis

USP31 AKAP13 TRIM42 KIF1B

2.94e-03594304MONDO_0005301
Diseaseplatelet-to-lymphocyte ratio

NOSTRIN RASA3 KIF1B

5.86e-03363303EFO_0008446
Diseasepneumonia, COVID-19

MAP2 RGS22

5.90e-03113302EFO_0003106, MONDO_0100096

Protein segments in the cluster

PeptideGeneStartEntry
SRTFSYIKNKMSSSK

AKAP13

1746

Q12802
ESLKKYKSTSSMDTS

C13orf42

51

A0A1B0GVH6
SESYGLSKMASKVTQ

ADAD1

41

Q96M93
TSKAGMSQKESSKSA

DIAPH1

131

O60610
KSSKFKSNSDSDYKG

CASP8AP2

301

Q9UKL3
SKSKSASFKESYMAT

RASA3

526

Q14644
NGKSYSLKASSTMAK

NRG3

401

P56975
NTMSKTSLGQSMSKY

KIF1B

1236

O60333
TLSKESKLYGMKDSA

KIAA1109

3906

Q2LD37
EKYLAMKTKSKSTSS

HERC1

3041

Q15751
MKTKSKSTSSERYKG

HERC1

3046

Q15751
GFTSNLYSSKKDDKM

LINC00474

6

Q9P2X8
LKSKSGESKSSAMSS

FAM120A

1031

Q9NZB2
RNLYKSMLEKSSSSS

FOXJ2

256

Q9P0K8
LKMSSTAGRKKSFST

OR5AK3P

226

Q8NH89
KNATMGYLTSSLSTK

F2RL2

81

O00254
SMSKSKSESKLYNGS

OSBPL8

91

Q9BZF1
MGMSSTKGKYKAFST

OR7D4

226

Q8NG98
LKMSSSAGRKKSFST

OR5AK2

226

Q8NH90
SMYSYEMKGKSDTSS

C1QTNF3

191

Q9BXJ4
MTSGEVKTSLKNAYS

DUSP29

1

Q68J44
LSATEYAKSTTSKSM

CCDC168

2206

Q8NDH2
SSYTKECGKKEMSLS

CENPI

316

Q92674
KKSSYMQDSAIDSSS

PTPN13

1201

Q12923
MLKTYSSTSSFSDAK

NOSTRIN

326

Q8IVI9
EGSKSMNSVKYSSLV

PIGB

211

Q92521
SSSMLSFSNTDKKAK

TRIM42

536

Q8IWZ5
LTNFKASSSTMSLKK

RGS22

1241

Q8NE09
SKKMSSELFTLTYGA

TRAPPC3

11

O43617
KSGMSKYFETSALKE

MAP2

566

P11137
SSRKMFCKKSGQSYS

WRNIP1

456

Q96S55
EKSSKKLSSSMQTSA

USP31

1331

Q70CQ4
LSSKYMTQGKASAKR

TUT7

1476

Q5VYS8