Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncalcium ion binding

NOTCH2NLA HMCN1 DLK2 NOTCH2NLC NOTCH2 NOTCH3 FBN1 PROS1

1.63e-06749248GO:0005509
GeneOntologyMolecularFunctionNotch binding

NOTCH2NLA DLK2

4.77e-0427242GO:0005112
GeneOntologyBiologicalProcessNotch signaling pathway

NOTCH2NLA DLK2 NOTCH2NLC NOTCH2 NOTCH3

3.79e-06210245GO:0007219
GeneOntologyBiologicalProcessglomerulus vasculature morphogenesis

NOTCH2 NOTCH3

1.94e-056242GO:0072103
GeneOntologyBiologicalProcessglomerular capillary formation

NOTCH2 NOTCH3

1.94e-056242GO:0072104
GeneOntologyBiologicalProcessrenal system vasculature morphogenesis

NOTCH2 NOTCH3

2.72e-057242GO:0061438
GeneOntologyBiologicalProcesskidney vasculature morphogenesis

NOTCH2 NOTCH3

2.72e-057242GO:0061439
GeneOntologyBiologicalProcessglomerulus morphogenesis

NOTCH2 NOTCH3

7.09e-0511242GO:0072102
GeneOntologyBiologicalProcessregulation of osteoclast development

NOTCH2 FBN1

1.00e-0413242GO:2001204
GeneOntologyBiologicalProcessactivation of protein kinase activity

CHRNA3 NOTCH2 FBN1

1.90e-0497243GO:0032147
GeneOntologyBiologicalProcessosteoclast development

NOTCH2 FBN1

2.96e-0422242GO:0036035
GeneOntologyBiologicalProcessbone cell development

NOTCH2 FBN1

2.96e-0422242GO:0098751
GeneOntologyBiologicalProcessregulation of Notch signaling pathway

NOTCH2NLA DLK2 NOTCH2NLC

3.06e-04114243GO:0008593
GeneOntologyBiologicalProcessglomerulus vasculature development

NOTCH2 NOTCH3

5.53e-0430242GO:0072012
GeneOntologyBiologicalProcesskidney vasculature development

NOTCH2 NOTCH3

5.91e-0431242GO:0061440
GeneOntologyBiologicalProcessrenal system vasculature development

NOTCH2 NOTCH3

5.91e-0431242GO:0061437
GeneOntologyBiologicalProcessregulation of protein kinase activity

CHRNA3 NOTCH2 MAP3K13 FBN1 SPRY4

5.98e-04611245GO:0045859
GeneOntologyBiologicalProcesspositive regulation of protein kinase activity

CHRNA3 NOTCH2 MAP3K13 FBN1

6.62e-04350244GO:0045860
GeneOntologyBiologicalProcesskidney development

WNT7B NOTCH2 NOTCH3 FBN1

8.31e-04372244GO:0001822
GeneOntologyBiologicalProcessrenal system development

WNT7B NOTCH2 NOTCH3 FBN1

9.54e-04386244GO:0072001
GeneOntologyBiologicalProcessregulation of kinase activity

CHRNA3 NOTCH2 MAP3K13 FBN1 SPRY4

1.01e-03686245GO:0043549
GeneOntologyBiologicalProcessnephron development

WNT7B NOTCH2 NOTCH3

1.05e-03174243GO:0072006
GeneOntologyBiologicalProcesspositive regulation of kinase activity

CHRNA3 NOTCH2 MAP3K13 FBN1

1.14e-03405244GO:0033674
GeneOntologyBiologicalProcesspositive regulation of protein phosphorylation

FAM20A CHRNA3 NOTCH2 MAP3K13 FBN1

1.28e-03724245GO:0001934
GeneOntologyBiologicalProcesscell morphogenesis involved in neuron differentiation

CHRNA3 WNT7B NOTCH2 NOTCH3 MAP3K13

1.48e-03748245GO:0048667
GeneOntologyBiologicalProcessregulation of protein phosphorylation

FAM20A CHRNA3 NOTCH2 MAP3K13 FBN1 SPRY4

1.55e-031133246GO:0001932
GeneOntologyBiologicalProcesspositive regulation of Notch signaling pathway

NOTCH2NLA NOTCH2NLC

1.72e-0353242GO:0045747
GeneOntologyBiologicalProcesspositive regulation of phosphorylation

FAM20A CHRNA3 NOTCH2 MAP3K13 FBN1

1.78e-03780245GO:0042327
GeneOntologyBiologicalProcessneuron projection morphogenesis

CHRNA3 WNT7B NOTCH2 NOTCH3 MAP3K13

2.01e-03802245GO:0048812
GeneOntologyBiologicalProcessregulation of transferase activity

CHRNA3 NOTCH2 MAP3K13 FBN1 SPRY4

2.10e-03810245GO:0051338
GeneOntologyBiologicalProcessregulation of MAPK cascade

GRM4 WNT7B NOTCH2 MAP3K13 SPRY4

2.16e-03815245GO:0043408
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

CHRNA3 WNT7B NOTCH2 NOTCH3 MAP3K13

2.21e-03819245GO:0120039
GeneOntologyBiologicalProcessforebrain development

NOTCH2NLA NOTCH2NLC WNT7B NOTCH3

2.28e-03489244GO:0030900
GeneOntologyBiologicalProcesspositive regulation of miRNA transcription

NOTCH2 NOTCH3

2.28e-0361242GO:1902895
GeneOntologyBiologicalProcessregulation of Ras protein signal transduction

NOTCH2 SPRY4

2.28e-0361242GO:0046578
GeneOntologyBiologicalProcesspositive regulation of transferase activity

CHRNA3 NOTCH2 MAP3K13 FBN1

2.29e-03490244GO:0051347
GeneOntologyBiologicalProcesscell projection morphogenesis

CHRNA3 WNT7B NOTCH2 NOTCH3 MAP3K13

2.29e-03826245GO:0048858
GeneOntologyBiologicalProcessregulation of phosphorylation

FAM20A CHRNA3 NOTCH2 MAP3K13 FBN1 SPRY4

2.32e-031226246GO:0042325
MousePhenocalcified artery

FAM20A FBN1

7.61e-0511172MP:0006133
MousePhenodecreased bone trabecula number

NOTCH2 NOTCH3 FBN1

7.78e-0570173MP:0010869
MousePhenodecreased trabecular bone connectivity density

NOTCH2 NOTCH3

1.65e-0416172MP:0010933
MousePhenolethality during fetal growth through weaning, incomplete penetrance

FAM20A CHRNA3 WNT7B NOTCH2 POGZ SPRY4 LPP

2.02e-041124177MP:0011112
MousePhenodecreased bone volume

NOTCH2 NOTCH3 FBN1

2.25e-04100173MP:0010876
MousePhenoabnormal thrombosis

NOTCH3 FBN1 PROS1

2.67e-04106173MP:0005048
MousePhenoshort tibia

FAM20A NOTCH2 FBN1 SPRY4

2.81e-04274174MP:0002764
MousePhenoabnormal trabecular bone connectivity density

NOTCH2 NOTCH3

4.80e-0427172MP:0010931
MousePhenoabnormal bone trabecula morphology

NOTCH2 NOTCH3 FBN1

5.31e-04134173MP:0010867
MousePhenoincreased bone ossification

NOTCH2 NOTCH3

6.76e-0432172MP:0020039
MousePhenoaneurysm

NOTCH2 FBN1

8.09e-0435172MP:0003279
MousePhenoabnormal urinary bladder physiology

CHRNA3 FBN1

9.04e-0437172MP:0010386
MousePhenoabnormal tibia morphology

FAM20A NOTCH2 FBN1 SPRY4

9.19e-04375174MP:0000558
MousePhenoincreased osteoblast cell number

NOTCH2 NOTCH3

9.54e-0438172MP:0004988
MousePhenoabnormal hindlimb zeugopod morphology

FAM20A NOTCH2 FBN1 SPRY4

9.75e-04381174MP:0003857
MousePhenoabnormal blood vessel morphology

FAM20A WNT7B NOTCH2 NOTCH3 FBN1 LPP PROS1

1.06e-031472177MP:0001614
MousePhenoabnormal bone volume

NOTCH2 NOTCH3 FBN1

1.11e-03173173MP:0010874
MousePhenoabnormal bone remodeling

NOTCH2 NOTCH3 FBN1

1.21e-03178173MP:0002998
MousePhenodecreased length of long bones

FAM20A NOTCH2 FBN1 SPRY4

1.27e-03409174MP:0004686
MousePhenoprenatal lethality, incomplete penetrance

KMT2C NOTCH2 POGZ FBN1 PROS1

1.55e-03747175MP:0011101
MousePhenolung hemorrhage

WNT7B FBN1

1.78e-0352172MP:0001182
MousePhenodecreased trabecular bone volume

NOTCH2 NOTCH3

2.36e-0360172MP:0010879
MousePhenoabnormal timing of postnatal eyelid opening

KMT2C CHRNA3

2.44e-0361172MP:0004874
DomainEGF_Ca-bd_CS

NOTCH2NLA HMCN1 DLK2 NOTCH2NLC NOTCH2 NOTCH3 FBN1 PROS1

2.71e-1397248IPR018097
DomainEGF_CA

NOTCH2NLA HMCN1 DLK2 NOTCH2NLC NOTCH2 NOTCH3 FBN1 PROS1

3.20e-1399248PS01187
DomainASX_HYDROXYL

NOTCH2NLA HMCN1 DLK2 NOTCH2NLC NOTCH2 NOTCH3 FBN1 PROS1

3.48e-13100248PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

NOTCH2NLA HMCN1 DLK2 NOTCH2NLC NOTCH2 NOTCH3 FBN1 PROS1

5.61e-13106248IPR000152
DomainEGF_CA

NOTCH2NLA HMCN1 DLK2 NOTCH2NLC NOTCH2 NOTCH3 FBN1 PROS1

1.77e-12122248SM00179
DomainEGF-like_Ca-bd_dom

NOTCH2NLA HMCN1 DLK2 NOTCH2NLC NOTCH2 NOTCH3 FBN1 PROS1

2.02e-12124248IPR001881
DomainEGF_CA

NOTCH2NLA HMCN1 NOTCH2NLC NOTCH2 NOTCH3 FBN1 PROS1

1.11e-1186247PF07645
DomainEGF

NOTCH2NLA HMCN1 DLK2 NOTCH2NLC NOTCH2 NOTCH3 PROS1

1.69e-10126247PF00008
DomainEGF_3

NOTCH2NLA HMCN1 DLK2 NOTCH2NLC NOTCH2 NOTCH3 FBN1 PROS1

3.45e-10235248PS50026
DomainEGF

NOTCH2NLA HMCN1 DLK2 NOTCH2NLC NOTCH2 NOTCH3 FBN1 PROS1

3.45e-10235248SM00181
DomainEGF-like_dom

NOTCH2NLA HMCN1 DLK2 NOTCH2NLC NOTCH2 NOTCH3 FBN1 PROS1

5.46e-10249248IPR000742
DomainEGF_1

NOTCH2NLA HMCN1 DLK2 NOTCH2NLC NOTCH2 NOTCH3 FBN1 PROS1

6.59e-10255248PS00022
DomainEGF-like_CS

NOTCH2NLA HMCN1 DLK2 NOTCH2NLC NOTCH2 NOTCH3 FBN1 PROS1

7.92e-10261248IPR013032
DomainEGF_2

NOTCH2NLA HMCN1 DLK2 NOTCH2NLC NOTCH2 NOTCH3 FBN1 PROS1

8.93e-10265248PS01186
DomainGrowth_fac_rcpt_

HMCN1 NOTCH2 NOTCH3 FBN1 PROS1

1.43e-06156245IPR009030
DomainDUF3454

NOTCH2 NOTCH3

4.74e-063242PF11936
DomainDUF3454_notch

NOTCH2 NOTCH3

4.74e-063242IPR024600
DomainDUF3454

NOTCH2 NOTCH3

4.74e-063242SM01334
DomainhEGF

DLK2 NOTCH2 NOTCH3

5.98e-0628243PF12661
DomainNOD

NOTCH2 NOTCH3

9.48e-064242PF06816
DomainNotch

NOTCH2 NOTCH3

9.48e-064242IPR008297
DomainNODP

NOTCH2 NOTCH3

9.48e-064242PF07684
DomainNotch_NODP_dom

NOTCH2 NOTCH3

9.48e-064242IPR011656
DomainNotch_NOD_dom

NOTCH2 NOTCH3

9.48e-064242IPR010660
DomainNOD

NOTCH2 NOTCH3

9.48e-064242SM01338
DomainNODP

NOTCH2 NOTCH3

9.48e-064242SM01339
DomainLNR

NOTCH2 NOTCH3

1.58e-055242PS50258
DomainNotch_dom

NOTCH2 NOTCH3

3.31e-057242IPR000800
DomainNotch

NOTCH2 NOTCH3

3.31e-057242PF00066
DomainNL

NOTCH2 NOTCH3

3.31e-057242SM00004
DomaincEGF

HMCN1 FBN1

5.05e-0426242IPR026823
DomaincEGF

HMCN1 FBN1

5.05e-0426242PF12662
DomainEGF_extracell

DLK2 NOTCH3

2.68e-0360242IPR013111
DomainEGF_2

DLK2 NOTCH3

2.68e-0360242PF07974
DomainLIM

CRIP1 LPP

3.52e-0369242PF00412
Domain-

CRIP1 LPP

3.62e-03702422.10.110.10
DomainLIM_DOMAIN_2

CRIP1 LPP

3.73e-0371242PS50023
DomainZnf_LIM

CRIP1 LPP

3.73e-0371242IPR001781
DomainLIM_DOMAIN_1

CRIP1 LPP

3.73e-0371242PS00478
DomainLIM

CRIP1 LPP

3.73e-0371242SM00132
Domainzf-C2H2

RLF ZNF709 POGZ ZFP64

1.11e-02693244PF00096
DomainZINC_FINGER_C2H2_2

RLF ZNF709 POGZ ZFP64

1.61e-02775244PS50157
DomainZINC_FINGER_C2H2_1

RLF ZNF709 POGZ ZFP64

1.63e-02777244PS00028
PathwayWP_CANONICAL_AND_NONCANONICAL_NOTCH_SIGNALING

DLK2 NOTCH2 NOTCH3

3.45e-0627163M39545
PathwayREACTOME_DEFECTIVE_LFNG_CAUSES_SCDO3

NOTCH2 NOTCH3

1.21e-055162M27411
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_THE_ENDOPLASMIC_RETICULUM

NOTCH2 NOTCH3

1.81e-056162M27068
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_PROTEOLYTIC_ACTIVATION

NOTCH2 NOTCH3

6.60e-0511162M47865
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00380

NOTCH2 NOTCH3

7.92e-0512162M47532
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00381

NOTCH2 NOTCH3

7.92e-0512162M47533
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_SIGNALING_PATHWAY

NOTCH2 NOTCH3

9.35e-0513162M47423
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00382

NOTCH2 NOTCH3

9.35e-0513162M47534
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI

NOTCH2 NOTCH3

1.83e-0418162M614
PathwayWP_OSTEOBLAST_DIFFERENTIATION_AND_RELATED_DISEASES

WNT7B NOTCH2 NOTCH3

2.96e-04118163M39852
PathwayKEGG_DORSO_VENTRAL_AXIS_FORMATION

NOTCH2 NOTCH3

3.29e-0424162M11190
PathwayREACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY

NOTCH2 NOTCH3

4.49e-0428162M6177
PathwayWP_BREAST_CANCER_PATHWAY

WNT7B NOTCH2 NOTCH3

6.45e-04154163M39739
PathwayWP_OSX_AND_MIRNAS_IN_TOOTH_DEVELOPMENT

NOTCH2 NOTCH3

6.63e-0434162M39390
PathwayWP_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_IN_COLORECTAL_CANCER

WNT7B NOTCH2 NOTCH3

7.34e-04161163M39770
PathwayWP_NOTCH_SIGNALING_WP268

NOTCH2 NOTCH3

1.16e-0345162M39571
PathwayWP_NOTCH_SIGNALING_PATHWAY

NOTCH2 NOTCH3

1.21e-0346162MM15971
PathwayKEGG_NOTCH_SIGNALING_PATHWAY

NOTCH2 NOTCH3

1.27e-0347162M7946
PathwayPID_NOTCH_PATHWAY

NOTCH2 NOTCH3

1.99e-0359162M17
PathwayWP_NOTCH_SIGNALING_WP61

NOTCH2 NOTCH3

2.13e-0361162M39540
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

NOTCH2 NOTCH3

2.63e-0368162M27303
PathwayWP_DELTANOTCH_SIGNALING_PATHWAY

NOTCH2 NOTCH3

3.80e-0382162MM15922
PathwayWP_NEURAL_CREST_DIFFERENTIATION

NOTCH2 NOTCH3

5.28e-0397162MM15926
PathwayWP_NEURAL_CREST_DIFFERENTIATION

NOTCH2 NOTCH3

5.71e-03101162M39448
Pubmed

Evolution of Human Brain Size-Associated NOTCH2NL Genes Proceeds toward Reduced Protein Levels.

NOTCH2NLA NOTCH2NLC NOTCH2

1.15e-09424332330268
Pubmed

Human-Specific NOTCH2NL Genes Affect Notch Signaling and Cortical Neurogenesis.

NOTCH2NLA NOTCH2NLC NOTCH2

2.88e-09524329856954
Pubmed

Effects of Notch2 and Notch3 on Cell Proliferation and Apoptosis of Trophoblast Cell Lines.

NOTCH2 NOTCH3

4.56e-07224226640406
Pubmed

Clinical impact of KMT2C and SPRY4 expression levels in intensively treated younger adult acute myeloid leukemia patients.

KMT2C SPRY4

4.56e-07224228940816
Pubmed

Expression of notch family proteins in placentas from patients with early-onset severe preeclampsia.

NOTCH2 NOTCH3

4.56e-07224224336671
Pubmed

Notch2 and Notch3 function together to regulate vascular smooth muscle development.

NOTCH2 NOTCH3

4.56e-07224222615991
Pubmed

NOTCH Single Nucleotide Polymorphisms in the Predisposition of Breast and Colorectal Cancers in Saudi Patients.

NOTCH2 NOTCH3

4.56e-07224234257585
Pubmed

Enhanced Notch3 signaling contributes to pulmonary emphysema in a Murine Model of Marfan syndrome.

NOTCH3 FBN1

4.56e-07224232616814
Pubmed

Genetic spectrum and clinical features of adult leukoencephalopathies in a Chinese cohort.

NOTCH2NLC NOTCH3

4.56e-07224237237429
Pubmed

Notch signaling in stomach epithelial stem cell homeostasis.

DLK2 NOTCH2 NOTCH3

1.04e-062924321402740
Pubmed

Overlapping but distinct roles for NOTCH receptors in human cardiovascular disease.

NOTCH2 NOTCH3

1.37e-06324229767458
Pubmed

The human NOTCH1, 2, and 3 genes are located at chromosome positions 9q34, 1p13-p11, and 19p13.2-p13.1 in regions of neoplasia-associated translocation.

NOTCH2 NOTCH3

1.37e-0632427698746
Pubmed

T-cell acute lymphoblastic leukemia in infants has distinct genetic and epigenetic features compared to childhood cases.

NOTCH2 NOTCH3

1.37e-06324227717083
Pubmed

Differential Regulation of NOTCH2 and NOTCH3 Contribute to Their Unique Functions in Vascular Smooth Muscle Cells.

NOTCH2 NOTCH3

1.37e-06324225957400
Pubmed

Expression of Notch 1, 2 and 3 is regulated by epithelial-mesenchymal interactions and retinoic acid in the developing mouse tooth and associated with determination of ameloblast cell fate.

NOTCH2 NOTCH3

1.37e-0632427615640
Pubmed

The novel Notch homologue mouse Notch 3 lacks specific epidermal growth factor-repeats and is expressed in proliferating neuroepithelium.

NOTCH2 NOTCH3

1.37e-0632427918097
Pubmed

Complementary and combinatorial patterns of Notch gene family expression during early mouse development.

NOTCH2 NOTCH3

1.37e-0632428645602
Pubmed

Expression of Notch1 to -4 and their ligands in renal cell carcinoma: a tissue microarray study.

NOTCH2 NOTCH3

1.37e-06324221471519
Pubmed

Effect of notch1,2,3 genes silicing on NF-κB signaling pathway of macrophages in patients with atherosclerosis.

NOTCH2 NOTCH3

1.37e-06324227697639
Pubmed

Notch signalling is linked to epidermal cell differentiation level in basal cell carcinoma, psoriasis and wound healing.

NOTCH2 NOTCH3

2.74e-06424211978185
Pubmed

Conservation of the biochemical mechanisms of signal transduction among mammalian Notch family members.

NOTCH2 NOTCH3

2.74e-06424211459941
Pubmed

Prognostic roles of mRNA expression of notch receptors in non-small cell lung cancer.

NOTCH2 NOTCH3

2.74e-06424228061457
Pubmed

The 4 Notch receptors play distinct and antagonistic roles in the proliferation and hepatocytic differentiation of liver progenitors.

NOTCH2 NOTCH3

2.74e-06424224145721
Pubmed

A switch in Notch gene expression parallels stem cell to endothelial transition in infantile hemangioma.

NOTCH2 NOTCH3

2.74e-06424220069356
Pubmed

Expression and clinical significance of Notch receptors in human renal cell carcinoma.

NOTCH2 NOTCH3

2.74e-06424219404845
Pubmed

Notch signaling pathway regulates the growth and the expression of inflammatory cytokines in mouse basophils.

NOTCH2 NOTCH3

2.74e-06424228669409
Pubmed

Evolution and cell-type specificity of human-specific genes preferentially expressed in progenitors of fetal neocortex.

NOTCH2NLA NOTCH2NLC

2.74e-06424229561261
Pubmed

Mouse jagged1 physically interacts with notch2 and other notch receptors. Assessment by quantitative methods.

NOTCH2 NOTCH3

2.74e-06424210551863
Pubmed

A deficiency of lunatic fringe is associated with cystic dilation of the rete testis.

NOTCH2 NOTCH3

2.74e-06424218801836
Pubmed

Evolutionary analysis of vertebrate Notch genes.

NOTCH2 NOTCH3

2.74e-06424211466531
Pubmed

Abnormal expression pattern of Notch receptors, ligands, and downstream effectors in the dorsolateral prefrontal cortex and amygdala of suicidal victims.

NOTCH2 NOTCH3

2.74e-06424224151014
Pubmed

Mutational analysis of NOTCH1, 2, 3 and 4 genes in common solid cancers and acute leukemias.

NOTCH2 NOTCH3

2.74e-06424218184405
Pubmed

Notch2 is required for maintaining sustentacular cell function in the adult mouse main olfactory epithelium.

NOTCH2 NOTCH3

2.74e-06424218155189
Pubmed

Characterization and developmental expression of the amphioxus homolog of Notch (AmphiNotch): evolutionary conservation of multiple expression domains in amphioxus and vertebrates.

NOTCH2 NOTCH3

2.74e-06424211401408
Pubmed

Notch Signaling Participates in TGF-β-Induced SOST Expression Under Intermittent Compressive Stress.

NOTCH2 NOTCH3

2.74e-06424227966788
Pubmed

MicroRNA miR145 regulates TGFBR2 expression and matrix synthesis in vascular smooth muscle cells.

NOTCH2 NOTCH3

2.74e-06424225323858
Pubmed

Notch signaling in the mammalian central nervous system: insights from mouse mutants.

NOTCH2 NOTCH3

2.74e-06424215917835
Pubmed

Novel MIR143-NOTCH fusions in benign and malignant glomus tumors.

NOTCH2 NOTCH3

2.74e-06424223999936
Pubmed

TNFα drives pulmonary arterial hypertension by suppressing the BMP type-II receptor and altering NOTCH signalling.

NOTCH2 NOTCH3

2.74e-06424228084316
Pubmed

Notch as a mediator of cell fate determination in hematopoiesis: evidence and speculation.

NOTCH2 NOTCH3

2.74e-06424210194420
Pubmed

NOTCH1 regulates osteoclastogenesis directly in osteoclast precursors and indirectly via osteoblast lineage cells.

NOTCH2 NOTCH3

2.74e-06424218156632
Pubmed

Notch pathway activity identifies cells with cancer stem cell-like properties and correlates with worse survival in lung adenocarcinoma.

NOTCH2 NOTCH3

2.74e-06424223444212
Pubmed

Functional conservation of mouse Notch receptor family members.

NOTCH2 NOTCH3

2.74e-0642428898100
Pubmed

Deregulated expression of Notch receptors in human hepatocellular carcinoma.

NOTCH2 NOTCH3

2.74e-06424217920003
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

NOTCH2NLA RLF KMT2C WNT7B NOTCH2 NOTCH3 ZFP64 LPP

4.41e-06148924828611215
Pubmed

Expression patterns of Notch receptors and their ligands Jagged and Delta in human placenta.

NOTCH2 NOTCH3

4.56e-06524221726900
Pubmed

Notch signaling in bulge stem cells is not required for selection of hair follicle fate.

NOTCH2 NOTCH3

4.56e-06524219211676
Pubmed

Notch expression in developing olfactory neuroepithelium.

NOTCH2 NOTCH3

4.56e-06524215076712
Pubmed

Human-Specific NOTCH2NL Genes Expand Cortical Neurogenesis through Delta/Notch Regulation.

NOTCH2NLA NOTCH2NLC

4.56e-06524229856955
Pubmed

A novel non-canonical Notch signaling regulates expression of synaptic vesicle proteins in excitatory neurons.

NOTCH2 NOTCH3

4.56e-06524227040987
Pubmed

Analysis of coding-polymorphisms in NOTCH-related genes reveals NUMBL poly-glutamine repeat to be associated with schizophrenia in Brazilian and Danish subjects.

NOTCH2 NOTCH3

4.56e-06524216899352
Pubmed

Notch and MAML-1 complexation do not detectably alter the DNA binding specificity of the transcription factor CSL.

NOTCH2 NOTCH3

4.56e-06524221124806
Pubmed

Chimeric analysis of Notch2 function: a role for Notch2 in the development of the roof plate of the mouse brain.

NOTCH2 NOTCH3

4.56e-06524212242712
Pubmed

Functional redundancy of the Notch gene family during mouse embryogenesis: analysis of Notch gene expression in Notch3-deficient mice.

NOTCH2 NOTCH3

4.56e-06524215882997
Pubmed

Assignment of the murine Notch2 and Notch3 genes to chromosomes 3 and 17.

NOTCH2 NOTCH3

4.56e-0652429570965
Pubmed

The liver-enriched lnc-LFAR1 promotes liver fibrosis by activating TGFβ and Notch pathways.

NOTCH2 NOTCH3

4.56e-06524228747678
Pubmed

Functional diversity of notch family genes in fetal lung development.

NOTCH2 NOTCH3

4.56e-06524215064243
Pubmed

A novel tumour-suppressor function for the Notch pathway in myeloid leukaemia.

NOTCH2 NOTCH3

4.56e-06524221562564
Pubmed

Intraovarian regulation of gonadotropin-dependent folliculogenesis depends on notch receptor signaling pathways not involving Delta-like ligand 4 (Dll4).

NOTCH2 NOTCH3

4.56e-06524223675950
Pubmed

MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors.

NOTCH2 NOTCH3

4.56e-06524211101851
Pubmed

RBP-L, a transcription factor related to RBP-Jkappa.

NOTCH2 NOTCH3

6.83e-0662429111338
Pubmed

Expression of Deltex1 during mouse embryogenesis: comparison with Notch1, 2 and 3 expression.

NOTCH2 NOTCH3

6.83e-06624211731257
Pubmed

Notch signaling is a critical regulator of allogeneic CD4+ T-cell responses mediating graft-versus-host disease.

NOTCH2 NOTCH3

6.83e-06624220870902
Pubmed

The intracellular domains of Notch1 and Notch2 are functionally equivalent during development and carcinogenesis.

NOTCH2 NOTCH3

6.83e-06624226062937
Pubmed

Aberrant expression of Notch signaling molecules in patients with immune thrombocytopenic purpura.

NOTCH2 NOTCH3

6.83e-06624219603167
Pubmed

ALDH maintains the stemness of lung adenoma stem cells by suppressing the Notch/CDK2/CCNE pathway.

NOTCH2 NOTCH3

6.83e-06624224671051
Pubmed

Interaction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways.

NOTCH2 NOTCH3

6.83e-06624218299578
Pubmed

Characterization of Notch receptor expression in the developing mammalian heart and liver.

NOTCH2 NOTCH3

6.83e-06624212244553
Pubmed

Profiling immunohistochemical expression of NOTCH1-3, JAGGED1, cMET, and phospho-MAPK in 100 carcinomas of unknown primary.

NOTCH2 NOTCH3

6.83e-06624222526456
Pubmed

Mouse Serrate-1 (Jagged-1): expression in the developing tooth is regulated by epithelial-mesenchymal interactions and fibroblast growth factor-4.

NOTCH2 NOTCH3

6.83e-0662429108364
Pubmed

Delta-notch signaling in odontogenesis: correlation with cytodifferentiation and evidence for feedback regulation.

NOTCH2 NOTCH3

6.83e-0662429882480
Pubmed

Cloning and functional characterization of the murine mastermind-like 1 (Maml1) gene.

NOTCH2 NOTCH3

6.83e-06624215019995
Pubmed

Epidermal growth factor-like domain 7 (EGFL7) modulates Notch signalling and affects neural stem cell renewal.

NOTCH2 NOTCH3

6.83e-06624219503073
Pubmed

Notch controls the magnitude of T helper cell responses by promoting cellular longevity.

NOTCH2 NOTCH3

6.83e-06624222615412
Pubmed

Epidermal Notch1 loss promotes skin tumorigenesis by impacting the stromal microenvironment.

NOTCH2 NOTCH3

6.83e-06624219573812
Pubmed

Notch lineages and activity in intestinal stem cells determined by a new set of knock-in mice.

NOTCH2 NOTCH3

6.83e-06624221991352
Pubmed

Niclosamide inhibits colon cancer progression through downregulation of the Notch pathway and upregulation of the tumor suppressor miR-200 family.

NOTCH2 NOTCH3

6.83e-06624227460529
Pubmed

Murine notch homologs (N1-4) undergo presenilin-dependent proteolysis.

NOTCH2 NOTCH3

9.56e-06724211518718
Pubmed

Differentiation of CD11c+ CX3CR1+ cells in the small intestine requires Notch signaling.

NOTCH2 NOTCH3

9.56e-06724224711412
Pubmed

Expression pattern of notch1, 2 and 3 and Jagged1 and 2 in lymphoid and stromal thymus components: distinct ligand-receptor interactions in intrathymic T cell development.

NOTCH2 NOTCH3

9.56e-06724210383933
Pubmed

Human ligands of the Notch receptor.

NOTCH2 NOTCH3

9.56e-06724210079256
Pubmed

Loss of Notch2 and Notch3 in vascular smooth muscle causes patent ductus arteriosus.

NOTCH2 NOTCH3

9.56e-06724226453897
Pubmed

Notch1 and 2 cooperate in limb ectoderm to receive an early Jagged2 signal regulating interdigital apoptosis.

NOTCH2 NOTCH3

9.56e-06724216169548
Pubmed

The distribution of Notch receptors and their ligands during articular cartilage development.

NOTCH2 NOTCH3

9.56e-06724212846471
Pubmed

P4 down-regulates Jagged2 and Notch1 expression during primordial folliculogenesis.

NOTCH2 NOTCH3

1.27e-05824222652674
Pubmed

Notch1 and Jagged1 expression by the developing pulmonary vasculature.

NOTCH2 NOTCH3

1.27e-05824212242716
Pubmed

Expression of Hairy/Enhancer of Split genes, Hes1 and Hes5, during murine nephron morphogenesis.

NOTCH2 NOTCH3

1.27e-05824215465493
Pubmed

Distinct expression patterns of notch family receptors and ligands during development of the mammalian inner ear.

NOTCH2 NOTCH3

1.27e-0582429858718
Pubmed

Cranial neural crest ablation of Jagged1 recapitulates the craniofacial phenotype of Alagille syndrome patients.

NOTCH2 NOTCH3

1.27e-05824222156581
Pubmed

Notch/Delta expression in the developing mouse lung.

NOTCH2 NOTCH3

1.27e-05824211044610
Pubmed

Dynamic expression patterns of the pudgy/spondylocostal dysostosis gene Dll3 in the developing nervous system.

NOTCH2 NOTCH3

1.64e-05924211118901
Pubmed

Notch-deficient skin induces a lethal systemic B-lymphoproliferative disorder by secreting TSLP, a sentinel for epidermal integrity.

NOTCH2 NOTCH3

1.64e-05924218507503
Pubmed

Notch1 signals through Jagged2 to regulate apoptosis in the apical ectodermal ridge of the developing limb bud.

NOTCH2 NOTCH3

1.64e-05924216245338
Pubmed

Identification of a family of mastermind-like transcriptional coactivators for mammalian notch receptors.

NOTCH2 NOTCH3

1.64e-05924212370315
Pubmed

Asparaginyl hydroxylation of the Notch ankyrin repeat domain by factor inhibiting hypoxia-inducible factor.

NOTCH2 NOTCH3

1.64e-05924217573339
Pubmed

Spatiotemporal expression of Notch receptors and ligands in developing mouse placenta.

NOTCH2 NOTCH3

2.05e-051024223665443
Pubmed

Intratumoural heterogeneity generated by Notch signalling promotes small-cell lung cancer.

NOTCH2 NOTCH3

2.05e-051024228489825
Pubmed

gamma-secretase functions through Notch signaling to maintain skin appendages but is not required for their patterning or initial morphogenesis.

NOTCH2 NOTCH3

2.05e-051024215525534
Pubmed

Dynamics of Notch pathway expression during mouse testis post-natal development and along the spermatogenic cycle.

NOTCH2 NOTCH3

2.05e-051024224015274
Pubmed

Notch4 signaling limits regulatory T-cell-mediated tissue repair and promotes severe lung inflammation in viral infections.

NOTCH2 NOTCH3

2.05e-051024233915108
InteractionNTN5 interactions

NOTCH2 NOTCH3 FBN1

2.25e-0624223int:NTN5
InteractionZNF408 interactions

NOTCH2NLA NOTCH2 NOTCH3 FBN1

1.70e-05145224int:ZNF408
InteractionZFP41 interactions

NOTCH2 NOTCH3 FBN1

3.18e-0557223int:ZFP41
InteractionZNF672 interactions

NOTCH2NLA NOTCH2

7.46e-0512222int:ZNF672
InteractionZNF709 interactions

ZNF709 NOTCH2

8.81e-0513222int:ZNF709
InteractionIGSF5 interactions

NOTCH2 NOTCH3

1.03e-0414222int:IGSF5
InteractionLTBP1 interactions

NOTCH2 NOTCH3 FBN1

1.33e-0492223int:LTBP1
InteractionZNF32 interactions

NOTCH2NLA NOTCH2

1.35e-0416222int:ZNF32
InteractionMAML2 interactions

NOTCH2 NOTCH3

1.53e-0417222int:MAML2
InteractionMAML3 interactions

NOTCH2 NOTCH3

2.14e-0420222int:MAML3
InteractionNOTCH4 interactions

NOTCH2 NOTCH3

2.36e-0421222int:NOTCH4
InteractionNOTCH3 interactions

DLK2 NOTCH2 NOTCH3

2.45e-04113223int:NOTCH3
InteractionCASR interactions

NOTCH2 NOTCH3

2.59e-0422222int:CASR
InteractionMYB interactions

RLF ZNF709 POGZ

3.95e-04133223int:MYB
InteractionLGALS1 interactions

SUSD2 CRIP1 NOTCH2 NOTCH3

4.18e-04332224int:LGALS1
InteractionZXDC interactions

NOTCH2 POGZ

4.54e-0429222int:ZXDC
CytobandEnsembl 112 genes in cytogenetic band chr1q21

NOTCH2NLA NOTCH2NLC POGZ

1.19e-03404243chr1q21
CytobandEnsembl 112 genes in cytogenetic band chr3q27

MAP3K13 LPP

2.04e-03128242chr3q27
GeneFamilyLIM domain containing

CRIP1 LPP

1.22e-03591621218
GeneFamilyAnkyrin repeat domain containing

NOTCH2 NOTCH3

1.89e-02242162403
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

RLF ZNF709 ZFP64

2.37e-0271816328
CoexpressionMURARO_PANCREAS_MESENCHYMAL_STROMAL_CELL

NOTCH2NLA HMCN1 SUSD2 NOTCH2 NOTCH3 FBN1 SPRY4

9.41e-07681227M39175
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HPERIC

CRIP1 NOTCH2 NOTCH3 FBN1 SPRY4 LPP

3.76e-05795226M39050
CoexpressionJONES_OVARY_NK_CELL

CRIP1 NOTCH3 FBN1

5.56e-0589223M48353
CoexpressionBOQUEST_STEM_CELL_UP

NOTCH2NLA CRIP1 NOTCH2 FBN1

6.10e-05261224M1834
CoexpressionFUKUSHIMA_TNFSF11_TARGETS

NOTCH2 NOTCH3

8.01e-0516222M2207
CoexpressionFUKUSHIMA_TNFSF11_TARGETS

NOTCH2 NOTCH3

8.01e-0516222MM1296
CoexpressionVART_KSHV_INFECTION_ANGIOGENIC_MARKERS_DN

WNT7B NOTCH2 NOTCH3

1.92e-04135223M5825
CoexpressionHU_FETAL_RETINA_FIBROBLAST

HMCN1 NOTCH2 NOTCH3 FBN1

2.72e-04385224M39264
CoexpressionHALLMARK_NOTCH_SIGNALING

NOTCH2 NOTCH3

3.29e-0432222M5903
CoexpressionHAY_BONE_MARROW_STROMAL

FAM20A CHRNA3 NOTCH3 FBN1 SPRY4

3.69e-04767225M39209
CoexpressionHE_LIM_SUN_FETAL_LUNG_C0_VASCULAR_SMC_2_CELL

HMCN1 CRIP1 NOTCH3

3.84e-04171223M45687
CoexpressionJONES_OVARY_PERICYTE

CRIP1 NOTCH3 FBN1

3.90e-04172223M48351
CoexpressionKATSANOU_ELAVL1_TARGETS_UP

HMCN1 SUSD2 NOTCH3

3.97e-04173223M2385
CoexpressionRUBENSTEIN_SKELETAL_MUSCLE_SMOOTH_MUSCLE_CELLS

CRIP1 NOTCH3 MAP3K13 LPP

4.70e-04445224M41746
CoexpressionKATSANOU_ELAVL1_TARGETS_UP

HMCN1 SUSD2 NOTCH3

5.06e-04188223MM1071
CoexpressionXIE_ST_HSC_S1PR3_OE_UP

HMCN1 SPRY4 PROS1

5.14e-04189223M41755
CoexpressionGSE29614_CTRL_VS_DAY3_TIV_FLU_VACCINE_PBMC_UP

HMCN1 GRM4 CRIP1

5.22e-04190223M4906
CoexpressionHE_LIM_SUN_FETAL_LUNG_C1_AT1_CELL

FAM20A SUSD2

5.67e-0442222M45688
CoexpressionNUYTTEN_NIPP1_TARGETS_DN

FAM20A CRIPT CRIP1 SPRY4 LPP

5.74e-04845225M18090
CoexpressionGSE37416_0H_VS_6H_F_TULARENSIS_LVS_NEUTROPHIL_DN

RLF MAP3K13 FBN1

5.88e-04198223M5346
CoexpressionGSE19941_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_NFKBP50_KO_MACROPHAGE_UP

FAM20A POGZ PROS1

5.97e-04199223M8119
CoexpressionGSE19941_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_NFKBP50_KO_MACROPHAGE_DN

FAM20A NOTCH2 PROS1

5.97e-04199223M8100
CoexpressionGSE39152_BRAIN_VS_SPLEEN_CD103_NEG_MEMORY_CD8_TCELL_DN

CRIPT ZFP64 LPP

6.06e-04200223M9071
CoexpressionGSE22886_IGM_MEMORY_BCELL_VS_BM_PLASMA_CELL_UP

NOTCH2NLA NOTCH2 POGZ

6.06e-04200223M4456
CoexpressionGSE17721_LPS_VS_POLYIC_12H_BMDC_UP

NOTCH3 ZFP64 LPP

6.06e-04200223M3814
CoexpressionGSE24210_CTRL_VS_IL35_TREATED_TCONV_CD4_TCELL_UP

CRIP1 NOTCH2 LPP

6.06e-04200223M7841
CoexpressionGSE24210_RESTING_TREG_VS_TCONV_UP

CRIP1 NOTCH2 LPP

6.06e-04200223M7839
CoexpressionPEREZ_TP53_AND_TP63_TARGETS

SUSD2 WNT7B NOTCH3

6.69e-04207223M14566
CoexpressionAtlaskidney_adult_Mesangium_Meis_top-relative-expression-ranked_1000

SUSD2 CRIP1 NOTCH3 FBN1 SPRY4 LPP PROS1

1.91e-05872227gudmap_kidney_adult_Mesangium_Meis_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_P1_bladder_B_emap-30374_k-means-cluster#1_top-relative-expression-ranked_500

SUSD2 CRIP1 FBN1 LPP

2.42e-05167224gudmap_developingLowerUrinaryTract_P1_bladder_B_500_k1
CoexpressionAtlaskidney_P0_JuxtaGlom_Ren1_top-relative-expression-ranked_500

CRIP1 NOTCH2 NOTCH3 FBN1 LPP

8.70e-05456225gudmap_kidney_P0_JuxtaGlom_Ren1_500
CoexpressionAtlasStromal Cells, St.31-38-44-.SLN, CD45- gp38- CD31- CD44-, Lymph Node, avg-2

SUSD2 NOTCH3 FBN1

9.02e-0585223GSM777067_100
ToppCellfacs-Skin-Skin_Anagen-18m-Epithelial-epidermal_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SUSD2 WNT7B NOTCH2 NOTCH3

1.77e-061732340f9c1d3298e59e6d22bb3306f0f445f490be8bbd
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SUSD2 CRIP1 NOTCH3 LPP

2.31e-0618523498547c1b1828b76da810ed86082182afaaacdb3f
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SUSD2 CRIP1 NOTCH3 LPP

2.31e-061852345f5df92b328be396941b5812d00454b5ff927d30
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CRIP1 NOTCH2 NOTCH3 SPRY4

2.56e-06190234106862ef44fcaa0971c3ba0147d13eb08015ca77
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FAM20A CRIP1 NOTCH3 FBN1

2.62e-061912349431ffd6b758f756609d9057de2023596e22b5d4
ToppCellfacs-Heart-LV-3m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SUSD2 NOTCH3 FBN1 LPP

2.62e-06191234b7a57691a4742070cee640e285c1f4d0da95baf1
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRIP1 NOTCH2 NOTCH3 LPP

2.67e-0619223443228bddca2f606ddcae9731f04c6b1502c4b85a
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRIP1 NOTCH2 NOTCH3 LPP

2.67e-06192234f5463c6bcc5c69ac562bec028f7a105c471f2fbe
ToppCellIPF-Epithelial-Club|Epithelial / Disease state, Lineage and Cell class

HMCN1 FAM20A SUSD2 LPP

2.67e-06192234356e7a820b744a0ac87352a8d0e6e8d9fa9ed7d2
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRIP1 NOTCH3 SPRY4 LPP

2.73e-0619323418e11d515147accef9aee26e934b358b445e18e2
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRIP1 NOTCH3 SPRY4 LPP

2.73e-061932347766f495f2f945802ef9a5b994cd00bb64d0dfe3
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CRIP1 NOTCH3 FBN1 LPP

2.73e-06193234800b0f5705fefcd3608e37801afae8a94474723e
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRIP1 NOTCH3 SPRY4 LPP

2.73e-06193234ce3e8cf30b7b4d5c7a8f3d64c21d81d2c3cab5c1
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRIP1 NOTCH2 NOTCH3 LPP

2.78e-061942343bff2e4eb16719ab7419b2f94c9c6e7302aa6629
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRIP1 NOTCH2 NOTCH3 LPP

2.78e-06194234fdaf61cbe7f77ff5358d150b38adb1fe3778e961
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CRIP1 NOTCH3 FBN1 LPP

2.84e-06195234c51b1bee79e77aa2ac444a4883ef533c0095eaad
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CRIP1 NOTCH3 FBN1 LPP

2.84e-0619523443d372373367b71243c6ea958aedccde4478618f
ToppCell3'-Child04-06-SmallIntestine-Mesenchymal-stromal_related|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HMCN1 FAM20A CHRNA3 FBN1

2.84e-061952341be9502577267ca2a04656a99d57e3e2f124d92e
ToppCell(2)_5-FU-(3)_LEPR+_perivascular_cells|(2)_5-FU / Stress and Cell class

SUSD2 CRIP1 NOTCH3 FBN1

2.90e-06196234cc0a172de71d9a1a882c9e78652dae70e007d012
ToppCellCOPD-Epithelial-Club|Epithelial / Disease state, Lineage and Cell class

FAM20A WNT7B NOTCH3 LPP

2.90e-06196234af96fb94886e9395f3e2cd0a293af29229d017fe
ToppCell10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-osteochondral_precursor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

FAM20A NOTCH3 FBN1 SPRY4

2.96e-06197234c165c6fd12dc649b39e920d8528e2eb65c61956b
ToppCellcellseq2-Mesenchymal-Myocytic-Myocytic_2-VSMC|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SUSD2 CRIP1 NOTCH3 LPP

3.14e-06200234fc802dd73f048881d9ddafd1b79ab3ca654510e2
ToppCellcellseq2-Mesenchymal-Myocytic-Myocytic_2|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SUSD2 CRIP1 NOTCH3 LPP

3.14e-06200234cffddb39960cd611428397c1ec4023192e8af5a7
ToppCellcellseq2-Mesenchymal|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SUSD2 CRIP1 NOTCH3 LPP

3.14e-062002346b558cce0d6047c7e85f428adff80c5ca3084ea4
ToppCellcellseq2-Mesenchymal-Myocytic|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SUSD2 CRIP1 NOTCH3 LPP

3.14e-06200234e60aebd20be8012fa2febf6585ed34ebd64ec9b3
ToppCellRV-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

SUSD2 NOTCH3 LPP

7.42e-0516023329c9b4770d0e73d59cffc7937b179484c76b6dcc
ToppCellfacs-Skin-Anagen-24m-Epithelial-bulge_keratinocyte|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMCN1 FAM20A CRIP1

8.42e-0516723378909f685ccd1321064eb0887caf9263e0e54879
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CRIP1 NOTCH2 NOTCH3

9.03e-051712334ede831aed364cb5271f49a8b09bb6d0452f9b35
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HMCN1 GRM4 NOTCH3

9.03e-05171233a4a2c5dc995589fbe3d4ca6ee1df888807e4ae34
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_4|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

SUSD2 WNT7B SPRY4

9.35e-05173233ef8d720b99470fe1953661f6e66bc0366266bdb6
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CRIP1 NOTCH3 LPP

9.35e-05173233901b8e6909c1f3849906fad9cee17b8f0bab050d
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NOTCH2NLA GRM4 LPP

9.35e-051732338ac2e9d39c0f76e674f8bd59d1da246bab4867c8
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CRIP1 NOTCH3 LPP

9.35e-05173233fc2602b2ce051cd4c33957d7e3d041ff8a529883
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CRIP1 NOTCH3 FBN1

9.51e-05174233778e0317c0c63fa4efd74114feb760975b819d92
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HMCN1 FBN1 LPP

9.67e-051752331799a7be623dc3bf53ba580a7c47d2619969d708
ToppCell3'-Adult-LymphNode-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SUSD2 CRIP1 NOTCH3

9.84e-0517623356e19240f4a7b617a986e3c0854b757394e78251
ToppCell3'-Adult-LymphNode-Mesenchymal-Pericytes|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SUSD2 CRIP1 NOTCH3

9.84e-05176233c88b46fe29ae7606c8880a6ff0ebb85c0dfda8bd
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-early_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMCN1 SPRY4 LPP

9.84e-0517623388ca2f83d8301633232735f39b0683efe49d0b86
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-early_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMCN1 SPRY4 LPP

9.84e-051762337292e014b8f697f0c2e9f47c48333de95cb44a69
ToppCellClub_cells-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

HMCN1 WNT7B NOTCH3

9.84e-0517623388c4ed0ab4a4ede8cad21385d799b723b5786cd9
ToppCelldroplet-Lung-nan-3m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM20A NOTCH3 SPRY4

1.00e-0417723365709bd546cb1ec6aa2ddd8b2adb46e174eb9a9a
ToppCellE12.5-Mesenchymal-myocytic_cell-vascular_associated_smooth_muscle_cell|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CRIP1 NOTCH3 FBN1

1.00e-041772335cdf413f82376a95467322b16d10b0d1e7557e2d
ToppCelldroplet-Lung-nan-3m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM20A NOTCH3 SPRY4

1.00e-041772338684d47a547e2a06496f15e8da0200ecddc431e0
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_G2M|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CRIP1 NOTCH3 FBN1

1.02e-041782339fc5688cf705a74398d24e10e0aab4758612e72b
ToppCelldroplet-Heart-nan-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SUSD2 NOTCH3 SPRY4

1.05e-0418023378fdcfb3fdbf36469cae78407cda5bd0996930d8
ToppCellE15.5-Mesenchymal-myocytic_cell-vascular_associated_smooth_muscle_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CRIP1 NOTCH3 FBN1

1.05e-0418023338035cf2c6fbc443ea10ca7e942572715ed572da
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SUSD2 CRIP1 NOTCH3

1.05e-041802334fb95ed39508bede5472dd36aeabe91b33631726
ToppCellfacs-Heart-RA-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SUSD2 NOTCH3 LPP

1.07e-04181233429df38438d5a7ff490c9ede34b69e2970c7ded2
ToppCellfacs-Heart-RA-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SUSD2 NOTCH3 LPP

1.07e-04181233395cf5aa2d89b05328ab516b8c89401020b6d830
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FAM20A CRIP1 NOTCH3

1.10e-04183233b4f29dd3994009bb5eb769d36d95886664e7f87d
ToppCellBasal|World / shred by cell class for mouse tongue

GRM4 DLK2 CRIP1

1.10e-04183233c6729a207526ff4aa48176207b9353176f631fea
ToppCellPND07-28-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_C|PND07-28-samps / Age Group, Lineage, Cell class and subclass

HMCN1 FBN1 LPP

1.14e-04185233427176ad9ab8d9511200fb0a132cfd1e835fe35c
ToppCellAT2_cells-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

FAM20A SUSD2 SPRY4

1.14e-041852333b3268e3f99121124e33086cac88479808d31630
ToppCellE17.5-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

HMCN1 FAM20A FBN1

1.14e-04185233c85bba1210f1d389add3e40be9b96abac40cf8c1
ToppCell(0)_MSCs-(00)_Lepr-MSC|World / Cell class and subclass of bone marrow stroma cells in homeostatis

SUSD2 NOTCH3 FBN1

1.16e-04186233f0d156167d7cc2cd8a76e5a364233e9f2170bc01
ToppCell(0)_MSCs|World / Cell class and subclass of bone marrow stroma cells in homeostatis

SUSD2 NOTCH3 FBN1

1.16e-04186233a832c1e0035bcd559722eccf262c145deb3494c7
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes-Immature_pericyte|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CRIP1 NOTCH3 SPRY4

1.18e-041872336820bfbe552ea5e62cfe699687b051a17d9fda61
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-Vascular_SMC_2|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

HMCN1 CRIP1 NOTCH3

1.18e-04187233406ff9327d3109fe1e251629c4c617b00a573dc2
ToppCell(2)_5-FU-(2)_LEPR+_perivascular_cells_and_VE-Cad+_vascular_cells_(mixed)|(2)_5-FU / Stress and Cell class

SUSD2 CRIP1 FBN1

1.18e-041872336bbf0f7fe203274dae8d582652f35cd3187c0065
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.1.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FAM20A SUSD2 SPRY4

1.18e-041872337c44cec1c26ca5907a495f2d7e633410e2e9728f
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

RLF KMT2C LPP

1.20e-04188233ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellCOPD-Stromal-SMC|Stromal / Disease state, Lineage and Cell class

CRIP1 NOTCH3 LPP

1.20e-041882339ffef4b01d0ddd6913c9ed6be79aeaaabd5e41ed
ToppCell11.5-Airway-Mesenchymal-Pericyte|Airway / Age, Tissue, Lineage and Cell class

HMCN1 CRIP1 NOTCH3

1.20e-04188233916971d8660fd20f616346953874e89d2cd13e88
ToppCell(2)_Fibroblasts-(20)_Fibro-1|World / Cell class and subclass of bone marrow stroma cells in homeostatis

HMCN1 CRIP1 FBN1

1.20e-04188233409a7b69d02e87084ca955e3fe6c77230dee8861
ToppCellP07-Mesenchymal-myocytic_cell-vascular_associated_smooth_muscle_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CRIP1 NOTCH3 LPP

1.20e-041882336ec22b79b19d57ea187f312907819dc2d01f3efe
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FAM20A SUSD2 SPRY4

1.21e-04189233da014519d6eb21bc2dc2ed65eafe638b42a068ed
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FAM20A SUSD2 SPRY4

1.21e-04189233e90ba6f6d7ba0698d04d84278aa035c28803733e
ToppCell5'-Adult-Appendix-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SUSD2 NOTCH3 LPP

1.21e-04189233b6bb4327b4560d07d2b728abcc5f144f428948a5
ToppCell5'-Adult-Appendix-Mesenchymal-Pericytes|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SUSD2 NOTCH3 LPP

1.21e-041892330daa8efac08dca9525d2b8d421952068cab4eb50
ToppCellE18.5-samps-Mesenchymal|E18.5-samps / Age Group, Lineage, Cell class and subclass

NOTCH2 FBN1 PROS1

1.21e-041892330c18d3de4720759cf802eefb4d0ddde2a9246a1a
ToppCellPND10|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HMCN1 FBN1 LPP

1.23e-04190233d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCellP07|World / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

HMCN1 CRIP1 FBN1

1.23e-0419023338a613a9bca0ba040c3ada00286d1ce6f83ab23a
ToppCell(1)_Control_(PBS)-(3)_LEPR+_perivascular_cells|World / Stress and Cell class

FAM20A NOTCH3 FBN1

1.23e-04190233ec0ab31266583a0966ac7615d5c0fabb7b7e66e8
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRIP1 NOTCH2 NOTCH3

1.25e-0419123396ff4cfbdcaec4b8568f9482d732dddd399121d3
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SUSD2 NOTCH3 LPP

1.25e-04191233cb75e6c36dbe2e091e407d691c063ec7c4fd5f90
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SUSD2 NOTCH3 LPP

1.25e-04191233b2cffea7860dd590b505ee0ebd51aa1978cb5e64
ToppCellfacs-Heart-LA-24m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SUSD2 NOTCH3 SPRY4

1.25e-041912339c5d88f0d3c834c2419ec3da74652175153ba9df
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SUSD2 CRIP1 NOTCH3

1.25e-04191233239c1e68eb1cbe3e137a99fbd6eeb8d64c919ffd
ToppCellfacs-Heart-LA-24m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SUSD2 NOTCH3 SPRY4

1.25e-04191233a7494191a92984e5f53610bbbedd6714e9169e1c
ToppCellIPF-Stromal-SMC|Stromal / Disease state, Lineage and Cell class

CRIP1 NOTCH3 LPP

1.27e-041922339b06c7336624ef21f8e5393725b56038a8028e57
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CRIP1 NOTCH3 SPRY4

1.27e-04192233430ef714bf2544d32f3fd96a55af010f79aa9be0
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRIP1 NOTCH2 NOTCH3

1.27e-0419223320fd69eb60b93d22d9be39de44b733db6d761dde
ToppCellP28-Mesenchymal-myocytic_cell-vascular_associated_smooth_muscle_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CRIP1 NOTCH3 LPP

1.27e-0419223387c7780cf72f4c204f2a5f6655309d47a23c08ae
ToppCell(0)_Normal/No_Treatment-(3)_LEPR+_perivascular_cells|(0)_Normal/No_Treatment / Stress and Cell class

SUSD2 NOTCH3 FBN1

1.27e-041922337a2ad0bdae647b88e799e62767605f2f3c5a426f
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CRIP1 NOTCH3 LPP

1.27e-0419223326d9207e72bbef5e0046de511e2c9ff752b726f3
ToppCellP15-Mesenchymal-myocytic_cell-vascular_associated_smooth_muscle_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CRIP1 NOTCH3 LPP

1.27e-04192233a476895b7b252c388d6346eacbc72f0115b1443e
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2|Adult / Lineage, Cell type, age group and donor

FAM20A MAP3K13 SPRY4

1.29e-04193233738f4f0a9ddde2432b429ab46838e353b1790589
ToppCellPND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CRIP1 NOTCH3 LPP

1.29e-041932339a2c1711dec9dd8c8313bcf25bb888ac8e86c3f3
ToppCell5'-Adult-Distal_Rectal-Mesenchymal-Pericytes|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SUSD2 NOTCH3 LPP

1.29e-041932337631bf3362b4fa061ffeab4879ab12c4708dc4c0
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Vascular_SMC_2|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

HMCN1 CRIP1 NOTCH3

1.29e-04193233360079cbaa18b74e4a48c5de40844faca076e1a6
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FAM20A CRIP1 NOTCH3

1.29e-04193233323d1f3f4fbeb93ba857fc135d8aa0b897f98ac5
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

HMCN1 NOTCH3 FBN1

1.29e-041932335de87fc94a6e58899ef4124cf4887ed3ff96163a
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CRIP1 NOTCH3 LPP

1.29e-0419323388916d9a7d831eb52848599917c04238f8f9812b
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CRIP1 NOTCH3 LPP

1.29e-041932337fc3ab7261c88c1df71744bf5b17e8e46c4300e0
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CRIP1 NOTCH3 SPRY4

1.29e-041932337386fadc13a437f3b0c99b5d116cd3c5f893529c
ToppCell5'-Adult-Distal_Rectal-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SUSD2 NOTCH3 LPP

1.29e-041932338d15c63f2ae48d0a00d7ef5fdafa917ab8ad0571
ToppCellPND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CRIP1 NOTCH3 LPP

1.29e-041932337c7aa5e2124830d0fa1df11b6413ec6cf780aad0
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SUSD2 NOTCH3 LPP

1.31e-04194233bf34737ae2dc218f890fbb9201c308b324415749
ToppCellPND28-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CRIP1 NOTCH3 LPP

1.31e-04194233aaecde88bd54134a938e76cdf059c1c2653e4e77
ToppCellP28-Mesenchymal-myocytic_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CRIP1 NOTCH3 LPP

1.31e-0419423383e45441c74b7f50b6725876b583229280179dc2
Druggamma-secretase inhibitor I

NOTCH2 NOTCH3

5.34e-064222CID011754711
DrugvgBE

NOTCH2 NOTCH3

1.33e-056222CID000193461
DrugMW167

NOTCH2 NOTCH3

1.87e-057222CID010312597
Drug2-nitroisocitrate

CHRNA3 NOTCH2 NOTCH3

2.85e-0562223CID000166578
DrugKaempferol [520-18-3]; Down 200; 14uM; PC3; HT_HG-U133A

NOTCH2 POGZ NOTCH3 LPP

3.25e-051932245839_DN
DrugPNU-0230031 [267429-39-0]; Up 200; 10uM; PC3; HT_HG-U133A

CHRNA3 ZFP64 MAP3K13 LPP

3.45e-051962244288_UP
DrugLorglumide sodium salt [97964-56-2]; Up 200; 8.4uM; PC3; HT_HG-U133A

GRM4 DLK2 CHRNA3 MAP3K13

3.52e-051972244658_UP
DrugTropicamide [1508-75-4]; Up 200; 14uM; PC3; HT_HG-U133A

DLK2 CHRNA3 ZFP64 MAP3K13

3.59e-051982243722_UP
Drugcyclobutylene AP5

GRM4 LPP

4.88e-0511222CID000126582
Druglead stearate

NOTCH2 NOTCH3 LPP

7.09e-0584223CID000061258
DiseaseLeukemia, Myelocytic, Acute

KMT2C NOTCH2 SPRY4 LPP

7.69e-06173224C0023467
Diseasecentral nervous system cancer (implicated_via_orthology)

NOTCH2 NOTCH3

1.11e-057222DOID:3620 (implicated_via_orthology)
Diseaseadenocarcinoma (implicated_via_orthology)

NOTCH2 NOTCH3

1.11e-057222DOID:299 (implicated_via_orthology)
DiseaseSquamous cell carcinoma of esophagus

KMT2C NOTCH2 NOTCH3

4.76e-0595223C0279626
DiseaseAcute Myeloid Leukemia, M1

KMT2C SPRY4 LPP

1.08e-04125223C0026998
DiseaseAcute Myeloid Leukemia (AML-M2)

KMT2C SPRY4 LPP

1.08e-04125223C1879321
DiseasePolyarthritis, Juvenile, Rheumatoid Factor Positive

FAM20A LPP PROS1

1.24e-04131223C4704862
DiseasePolyarthritis, Juvenile, Rheumatoid Factor Negative

FAM20A LPP PROS1

1.24e-04131223C4552091
DiseaseJuvenile arthritis

FAM20A LPP PROS1

1.24e-04131223C3495559
DiseaseJuvenile psoriatic arthritis

FAM20A LPP PROS1

1.24e-04131223C3714758
DiseaseJuvenile-Onset Still Disease

FAM20A LPP PROS1

1.35e-04135223C0087031
Diseasebrain cancer (implicated_via_orthology)

NOTCH2 NOTCH3

1.71e-0426222DOID:1319 (implicated_via_orthology)
Diseasecolorectal cancer (implicated_via_orthology)

NOTCH2 NOTCH3

2.28e-0430222DOID:9256 (implicated_via_orthology)
Diseaseintestinal cancer (implicated_via_orthology)

NOTCH2 NOTCH3

2.60e-0432222DOID:10155 (implicated_via_orthology)
Diseasealcohol use disorder (implicated_via_orthology)

CHRNA3 NOTCH2 NOTCH3

3.99e-04195223DOID:1574 (implicated_via_orthology)
DiseaseBreast adenocarcinoma

NOTCH2 MAP3K13

4.28e-0441222C0858252
DiseaseNeoplasm of uncertain or unknown behavior of breast

NOTCH2 MAP3K13

4.28e-0441222C0496956
Diseaselung adenocarcinoma (is_implicated_in)

KMT2C CHRNA3

6.11e-0449222DOID:3910 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
CKEGYPCQDGMCGYC

CHRNA3

391

P32297
MPCCWHCEPCTGYQY

GRM4

536

Q14833
HEGKPYCNHPCYAAM

CRIP1

46

P50238
MCVTYHNGTGYCKCP

NOTCH2NLA

1

Q7Z3S9
YTCICNPGYMGAICS

NOTCH2

591

Q04721
GYTCHCVLPYTGKNC

NOTCH2

816

Q04721
KCTQMYHYPCAAGAG

KMT2C

301

Q8NEZ4
FYCACPMGKTGLLCH

NOTCH3

336

Q9UM47
TGKAYHPHCFTCVMC

LPP

491

Q93052
MCVTYHNGTGYCKCP

NOTCH2NLC

1

P0DPK4
PCSHSCHNAMGTYYC

HMCN1

5116

Q96RW7
CHNAMGTYYCSCPKG

HMCN1

5121

Q96RW7
APCYCIIMEYCAHGQ

MAP3K13

226

O43283
SCHNTLGSYKCMCPA

FBN1

2621

P35555
HYCQGCAYKKGICAM

CRIPT

71

Q9P021
QCMYDGGGEYHCVCL

DLK2

106

Q6UY11
VDTNGGCPYAYCRMH

ERVFC1

101

P60507
YGCDMEQGSVCTYHP

SUSD2

331

Q9UGT4
YGTCMCLVQGIFYHC

SPRY4

196

Q9C004
YMCKTEYAVCGNPHL

FAM20A

321

Q96MK3
RGHMCYCCPEMVEYQ

POGZ

391

Q7Z3K3
MCAQLCVNYPGGYTC

PROS1

251

P07225
TMCCGRGYNTHQYTK

WNT7B

306

P56706
HCGPQPYMCVSIDCY

RLF

736

Q13129
PYECSVCGKDYMCHS

ZNF709

101

Q8N972
CCYPGCQFKTAYGMK

ZFP64

146

Q9NTW7