Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionphosphatidylinositol phosphate 4-phosphatase activity

INPP5F SACM1L SYNJ2 FIG4

4.31e-07101374GO:0034596
GeneOntologyMolecularFunctionphosphatidylinositol-4-phosphate phosphatase activity

INPP5F SACM1L FIG4

1.26e-0641373GO:0043812
GeneOntologyMolecularFunctionphosphatidylinositol monophosphate phosphatase activity

INPP5F SACM1L SYNJ2 FIG4

2.73e-06151374GO:0052744
GeneOntologyMolecularFunctionphosphatidylinositol phosphate phosphatase activity

INPP5F SACM1L SYNJ2 FIG4

5.06e-05301374GO:0052866
GeneOntologyMolecularFunctionphosphatidylinositol phosphate 5-phosphatase activity

INPP5F SYNJ2 FIG4

8.59e-05131373GO:0034595
GeneOntologyMolecularFunctionphosphatidylinositol-3-phosphate phosphatase activity

SACM1L SYNJ2 FIG4

1.09e-04141373GO:0004438
GeneOntologyMolecularFunctionphosphatidylinositol-3,5-bisphosphate phosphatase activity

SACM1L SYNJ2 FIG4

1.66e-04161373GO:0106018
GeneOntologyMolecularFunctionphosphatidylinositol-3,5-bisphosphate 5-phosphatase activity

SYNJ2 FIG4

6.88e-0461372GO:0043813
GeneOntologyMolecularFunctioncullin family protein binding

KLHL3 RNF7 DCUN1D3

7.32e-04261373GO:0097602
GeneOntologyMolecularFunctionphosphatidylinositol bisphosphate phosphatase activity

SACM1L SYNJ2 FIG4

8.19e-04271373GO:0034593
GeneOntologyBiologicalProcesspost-translational protein modification

CYLD USP34 TRIML1 ABCA2 CAND1 RNF152 LRSAM1 UBR4 LRRK2 USP24 USP9Y TRIM52 CUL5 KLHL3 RNF7 RNF38 DCUN1D3 TRIM49B CRBN PINK1

2.53e-05107413620GO:0043687
GeneOntologyBiologicalProcessprotein modification by small protein conjugation or removal

CYLD USP34 TRIML1 CAND1 RNF152 LRSAM1 UBR4 LRRK2 USP24 USP9Y TRIM52 CUL5 KLHL3 RNF7 RNF38 DCUN1D3 TRIM49B CRBN PINK1

3.54e-05100913619GO:0070647
GeneOntologyBiologicalProcessnegative regulation of vacuolar transport

LRRK2 VPS35

4.32e-0521362GO:1903336
GeneOntologyBiologicalProcessnegative regulation of late endosome to lysosome transport

LRRK2 VPS35

4.32e-0521362GO:1902823
GeneOntologyBiologicalProcessphosphatidylinositol dephosphorylation

INPP5F SACM1L SYNJ2 FIG4

4.34e-05301364GO:0046856
DomainARM-type_fold

USP34 CAND1 ZBTB7C UBR4 LRRK2 INTS1 USP24 FHOD3 USP9Y ARMCX1 NCDN RYR3 FOCAD NOM1 VPS35 PPP6R2 STAG3 GPRASP2

5.11e-1133913618IPR016024
DomainSyja_N

INPP5F SACM1L SYNJ2 FIG4

1.34e-0851364PF02383
DomainSAC

INPP5F SACM1L SYNJ2 FIG4

1.34e-0851364PS50275
DomainSAC_dom

INPP5F SACM1L SYNJ2 FIG4

1.34e-0851364IPR002013
DomainNACHT

NLRP7 NLRP14 CIITA NLRP4

2.14e-05231364PS50837
DomainNACHT_NTPase

NLRP7 NLRP14 CIITA NLRP4

2.14e-05231364IPR007111
DomainAnkyrin_rpt

RAPH1 PPP1R12B POTEG LRRK2 POTEB2 TNNI3K POTEJ POTEH POTEB PPP1R16A

2.24e-0526213610IPR002110
DomainEIF3C_N_dom

EIF3CL EIF3C

5.26e-0521362IPR008905
DomaineIF-3c_N

EIF3CL EIF3C

5.26e-0521362PF05470
DomainEIF3C

EIF3CL EIF3C

5.26e-0521362IPR027516
DomainAnkyrin_rpt-contain_dom

PPP1R12B POTEG LRRK2 POTEB2 TNNI3K POTEJ POTEH POTEB PPP1R16A

1.03e-042541369IPR020683
DomainARM-like

SETX CAND1 LRRK2 FHOD3 USP9Y ARMCX1 PPP6R2 STAG3 GPRASP2

1.63e-042701369IPR011989
DomainANK

PPP1R12B POTEG POTEB2 TNNI3K POTEJ POTEH POTEB PPP1R16A

5.11e-042511368SM00248
DomainDAPIN

NLRP7 NLRP14 NLRP4

5.26e-04221363PS50824
DomainPYRIN

NLRP7 NLRP14 NLRP4

5.26e-04221363SM01289
DomainPYRIN

NLRP7 NLRP14 NLRP4

5.26e-04221363PF02758
DomainDAPIN

NLRP7 NLRP14 NLRP4

5.26e-04221363IPR004020
DomainANK_REPEAT

PPP1R12B POTEG POTEB2 TNNI3K POTEJ POTEH POTEB PPP1R16A

5.38e-042531368PS50088
DomainANK_REP_REGION

PPP1R12B POTEG POTEB2 TNNI3K POTEJ POTEH POTEB PPP1R16A

5.52e-042541368PS50297
Domain-

DSP DST

7.75e-04613623.90.1290.10
DomainPlectin

DSP DST

1.08e-0371362PF00681
DomainPlectin_repeat

DSP DST

1.08e-0371362IPR001101
DomainPLEC

DSP DST

1.08e-0371362SM00250
DomainUSP_CS

CYLD USP34 USP24 USP9Y

1.37e-03661364IPR018200
DomainAnk

PPP1R12B POTEG TNNI3K POTEJ POTEH POTEB PPP1R16A

1.42e-032281367PF00023
DomainUSP_1

CYLD USP34 USP24 USP9Y

1.70e-03701364PS00972
DomainUCH

CYLD USP34 USP24 USP9Y

1.79e-03711364PF00443
DomainUSP_2

CYLD USP34 USP24 USP9Y

1.79e-03711364PS00973
DomainCopine

CPNE8 CPNE9

1.83e-0391362PF07002
DomainCopine

CPNE8 CPNE9

1.83e-0391362IPR010734
DomainUSP_3

CYLD USP34 USP24 USP9Y

1.89e-03721364PS50235
DomainUSP_dom

CYLD USP34 USP24 USP9Y

1.89e-03721364IPR028889
DomainPeptidase_C19_UCH

CYLD USP34 USP24 USP9Y

1.89e-03721364IPR001394
Domain-

PPP1R12B POTEG LRRK2 POTEB2 POTEJ POTEH PPP1R16A

2.29e-0324813671.25.40.20
DomainARM-rpt_dom

ARMCX1 GPRASP2

2.77e-03111362IPR006911
DomainArm_2

ARMCX1 GPRASP2

2.77e-03111362PF04826
DomainABC_A

ABCA2 ABCA7

3.31e-03121362IPR026082
DomainSPRY

TRIML1 DDX1 RYR3 TRIM49B

3.75e-03871364SM00449
Domain-

NLRP7 TNFRSF11B NLRP14 NLRP4

4.76e-039313641.10.533.10
DomainAnk_2

PPP1R12B POTEG POTEB2 POTEJ POTEH PPP1R16A

4.94e-032151366PF12796
DomainSPRY

TRIML1 DDX1 RYR3 TRIM49B

4.95e-03941364PF00622
DomainSPRY_dom

TRIML1 DDX1 RYR3 TRIM49B

4.95e-03941364IPR003877
DomainEF-hand_1

NOX5 CAPN1 LCP1 RYR3 DST

5.12e-031521365PF00036
DomainB30.2/SPRY

TRIML1 DDX1 RYR3 TRIM49B

5.14e-03951364IPR001870
DomainB302_SPRY

TRIML1 DDX1 RYR3 TRIM49B

5.14e-03951364PS50188
DomainConA-like_dom

TRIML1 DDX1 RYR3 THBS2 PTPRK TRIM49B

5.40e-032191366IPR013320
DomainPINT

EIF3CL EIF3C

5.91e-03161362SM00088
DomainDEATH-like_dom

NLRP7 TNFRSF11B NLRP14 NLRP4

5.94e-03991364IPR011029
DomainEFh

EFCAB6 NOX5 CAPN1 LCP1 DST

6.02e-031581365SM00054
DomainZF_RING_2

TRIML1 RNF152 LRSAM1 TRIM52 RNF7 RNF38 TRIM49B

6.23e-032981367PS50089
DomainPCI_dom

EIF3CL EIF3C

6.66e-03171362IPR000717
DomainPCI

EIF3CL EIF3C

6.66e-03171362PF01399
DomainEF_HAND_2

EFCAB6 NOX5 CAPN1 LCP1 RYR3 DST

6.95e-032311366PS50222
DomainRING

TRIML1 RNF152 LRSAM1 TRIM52 RNF7 RNF38 TRIM49B

7.05e-033051367SM00184
DomainEF_hand_dom

EFCAB6 NOX5 CAPN1 LCP1 RYR3 DST

7.10e-032321366IPR002048
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

PLEKHB2 CYLD USP34 PDE2A ABCA2 CAND1 DSP LRSAM1 UBR4 USP9Y AKAP8L TRIM52 RYR3 FOCAD FBN1 DST APPL2 PTPRK SACS ARHGEF10 RNF38 EXOC1 EIF3C GPRASP2 PINK1

4.51e-1112851382535914814
Pubmed

Two novel transcripts encoding two Ankyrin repeat containing proteins have preponderant expression during the mouse spermatogenesis.

POTEG POTEB2 POTEH POTEB

3.54e-096138417171436
Pubmed

POTE, a highly homologous gene family located on numerous chromosomes and expressed in prostate, ovary, testis, placenta, and prostate cancer.

POTEB2 POTEJ POTEH POTEB

1.64e-088138412475935
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

KNTC1 USP34 PDE3A CAND1 PSMA1 LRSAM1 CAPN1 UBR4 USP24 DDI2 VPS36 NCDN NPLOC4 DDX1 EIF3CL SPDL1 CUL5 APPL2 ARHGEF10 VPS35 EIF3C

3.10e-0714551382122863883
Pubmed

Characterization of the mammalian family of DCN-type NEDD8 E3 ligases.

CAND1 CUL5 RNF7 DCUN1D3

6.95e-0718138426906416
Pubmed

Five POTE paralogs and their splice variants are expressed in human prostate and encode proteins of different lengths.

POTEG POTEH POTEB

2.11e-067138315276201
Pubmed

The Vertebrate Genome Annotation browser 10 years on.

POTEG POTEB2 TTC34 KCNMA1 POTEJ POTEH POTEB

4.23e-06163138724316575
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

KNTC1 NLRP7 RAPH1 DSP PCDHGA11 PPP1R12B UBR4 CCDC150 VPS36 LCP1 TERF2 AKAP8L DDX1 BPTF DST SACS VPS35 KRT40 POTEJ

4.52e-0614421381935575683
Pubmed

Interaction of TAGLN and USP1 promotes ZEB1 ubiquitination degradation in UV-induced skin photoaging.

USP34 USP24 USP9Y

5.05e-069138337149635
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

USP34 RAPH1 DSP UBR4 USP24 INPP5F AKAP8L SPDL1 DST GPRASP2

7.12e-064181381034709266
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

USP34 IFT140 ABCA2 SETX CAND1 INPP5F NPLOC4 TUBGCP6 DST SYNJ2 CARNS1

9.20e-065291381114621295
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

SETX AKAP8L NCDN NPLOC4 DDX1 SACM1L CUL5 DST NOM1 PRKCI PPP6R2 CMTR2

1.18e-056501381238777146
Pubmed

Rab40c regulates focal adhesions and PP6 activity by controlling ANKRD28 ubiquitylation.

CUL5 RNF7 PPP6R2

1.31e-0512138335512830
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

CAND1 DSP PSMA1 CAPN1 LRRK2 VPS36 LCP1 SLC44A4 VPS13D GK2 APPL2 VPS35 ATP6V0A4 GSTCD PRKCI

1.34e-0510161381519056867
Pubmed

Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

IFT140 ABCA2 VPS13D DST SYNJ2 CARNS1

1.39e-05130138612421765
Pubmed

Temporal and spatial mouse brain expression of cereblon, an ionic channel regulator involved in human intelligence.

KCNMA1 CRBN

1.56e-052138220131966
Pubmed

Epigenetic Regulation of Phosphodiesterases 2A and 3A Underlies Compromised β-Adrenergic Signaling in an iPSC Model of Dilated Cardiomyopathy.

PDE2A PDE3A

1.56e-052138226095046
Pubmed

Distribution of PINK1 and LRRK2 in rat and mouse brain.

LRRK2 PINK1

1.56e-052138216771836
Pubmed

Kinase signaling dysfunction in Parkinson's disease: a reverse genetic approach in Drosophila.

LRRK2 PINK1

1.56e-052138222486164
Pubmed

EIF3C Promotes Lung Cancer Tumorigenesis by Regulating the APP/HSPA1A/LMNB1 Axis.

EIF3CL EIF3C

1.56e-052138236157221
Pubmed

ADAMTSL6β protein rescues fibrillin-1 microfibril disorder in a Marfan syndrome mouse model through the promotion of fibrillin-1 assembly.

THSD4 FBN1

1.56e-052138221880733
Pubmed

LRRK2 Expression Is Deregulated in Fibroblasts and Neurons from Parkinson Patients with Mutations in PINK1.

LRRK2 PINK1

1.56e-052138227975167
Pubmed

An siRNA library screen identifies CYLD and USP34 as deubiquitinases that regulate GPCR-p38 MAPK signaling and distinct inflammatory responses.

CYLD USP34

1.56e-052138237865315
Pubmed

Dopaminergic neurodegeneration induced by Parkinson's disease-linked G2019S LRRK2 is dependent on kinase and GTPase activity.

LRRK2 VPS35

1.56e-052138232631998
Pubmed

Identification and characterization of a sac domain-containing phosphoinositide 5-phosphatase.

INPP5F FIG4

1.56e-052138211274189
Pubmed

Comparative Analysis of cul5 and rbx2 Expression in the Developing and Adult Murine Brain and Their Essentiality During Mouse Embryogenesis.

CUL5 RNF7

1.56e-052138230269386
Pubmed

VPS35 and retromer dysfunction in Parkinson's disease.

LRRK2 VPS35

1.56e-052138238368930
Pubmed

Differential regulation of human platelet responses by cGMP inhibited and stimulated cAMP phosphodiesterases.

PDE2A PDE3A

1.56e-052138212038792
Pubmed

Pharmacological rescue of mitochondrial deficits in iPSC-derived neural cells from patients with familial Parkinson's disease.

LRRK2 PINK1

1.56e-052138222764206
Pubmed

Dysregulation of large-conductance Ca2+-activated K+ channel expression in nonsyndromal mental retardation due to a cereblon p.R419X mutation.

KCNMA1 CRBN

1.56e-052138218414909
Pubmed

Intrinsic flexibility of NLRP pyrin domains is a key factor in their conformational dynamics, fold stability, and dimerization.

NLRP14 NLRP4

1.56e-052138225403012
Pubmed

ADAMTSL-6 is a novel extracellular matrix protein that binds to fibrillin-1 and promotes fibrillin-1 fibril formation.

THSD4 FBN1

1.56e-052138219940141
Pubmed

What lysosomes actually tell us about Parkinson's disease?

LRRK2 VPS35

1.56e-052138226947123
Pubmed

The genetics of NOD-like receptors in Crohn's disease.

NLRP7 NLRP14 NLRP4

2.15e-0514138320403135
Pubmed

NALPs: a novel protein family involved in inflammation.

NLRP7 NLRP14 NLRP4

2.15e-0514138312563287
Pubmed

Rab40-Cullin5 complex regulates EPLIN and actin cytoskeleton dynamics during cell migration.

CUL5 RNF7 DST

3.30e-0516138333999101
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

CYLD DOCK4 SETX RAPH1 DSP INPP5F DDX1 VPS13D DST AKAP9 ARHGEF10 SYNJ2 PRKCI

4.12e-058611381336931259
Pubmed

USP45 and Spindly are part of the same complex implicated in cell migration.

USP34 CPNE8 CAND1 CPNE9 SPDL1 VPS13D EIF3C

4.50e-05235138730258100
Pubmed

Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.

USP34 CAND1 DSP UBR4 INTS1 DST VPS35 EXOC1

4.63e-05322138826514267
Pubmed

The mouse germ-cell-specific leucine-rich repeat protein NALP14: a member of the NACHT nucleoside triphosphatase family.

NLRP14 NLRP4

4.68e-053138215590904
Pubmed

A comparative study of LRRK2, PINK1 and genetically undefined familial Parkinson's disease.

LRRK2 PINK1

4.68e-053138219726410
Pubmed

Differential regulation of endothelial cell permeability by cGMP via phosphodiesterases 2 and 3.

PDE2A PDE3A

4.68e-053138217704206
Pubmed

Interferon-γ resets muscle cell fate by stimulating the sequential recruitment of JARID2 and PRC2 to promoters to repress myogenesis.

JARID2 CIITA

4.68e-053138224327761
Pubmed

Iloprost- and isoproterenol-induced increases in cAMP are regulated by different phosphodiesterases in erythrocytes of both rabbits and humans.

PDE2A PDE3A

4.68e-053138219252089
Pubmed

RAB7L1 interacts with LRRK2 to modify intraneuronal protein sorting and Parkinson's disease risk.

LRRK2 VPS35

4.68e-053138223395371
Pubmed

Single molecule array measures of LRRK2 kinase activity in serum link Parkinson's disease severity to peripheral inflammation.

LRRK2 VPS35

4.68e-053138238862989
Pubmed

The Parkinson's disease VPS35[D620N] mutation enhances LRRK2-mediated Rab protein phosphorylation in mouse and human.

LRRK2 VPS35

4.68e-053138229743203
Pubmed

Relationship of DDX1 and NAG gene amplification/overexpression to the prognosis of patients with MYCN-amplified neuroblastoma.

DDX1 NBAS

4.68e-053138217028906
Pubmed

Biochemical characterization of copine: a ubiquitous Ca2+-dependent, phospholipid-binding protein.

CPNE8 CPNE9

4.68e-053138211123945
Pubmed

Protein kinase Ciota promotes nicotine-induced migration and invasion of cancer cells via phosphorylation of micro- and m-calpains.

CAPN1 PRKCI

4.68e-053138216361262
Pubmed

Endogenous Rab29 does not impact basal or stimulated LRRK2 pathway activity.

LRRK2 VPS35

4.68e-053138233135724
Pubmed

Cellular requirements for bovine immunodeficiency virus Vif-mediated inactivation of bovine APOBEC3 proteins.

CUL5 RNF7

4.68e-053138225142583
Pubmed

Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

DOCK4 USP34 DST AKAP9 SACS

5.34e-0510113859872452
Pubmed

The glomuvenous malformation protein Glomulin binds Rbx1 and regulates cullin RING ligase-mediated turnover of Fbw7.

CAND1 CUL5 RNF7

5.65e-0519138322405651
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

KNTC1 USP34 CPNE8 CAND1 PSMA1 UBR4 AKAP8L NPLOC4 DDX1 SACM1L CUL5 NBAS DST NOM1 VPS35 EXOC1 EIF3C

5.95e-0514401381730833792
Pubmed

Systematic analysis of dimeric E3-RING interactions reveals increased combinatorial complexity in human ubiquitination networks.

TRIML1 LRSAM1 TRIM52 RNF7 RNF38

6.42e-05105138522493164
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

CYLD KNTC1 TEAD1 INPP5F AKAP8L DST AKAP9 PRKCI PPP6R2

7.72e-05446138924255178
Pubmed

TIF1γ inhibits lung adenocarcinoma EMT and metastasis by interacting with the TAF15/TBP complex.

CAND1 DSP DDX1 EIF3CL BPTF VPS35

8.37e-05179138636261009
Pubmed

Coupled monoubiquitylation of the co-E3 ligase DCNL1 by Ariadne-RBR E3 ubiquitin ligases promotes cullin-RING ligase complex remodeling.

CAND1 CUL5 RNF7

8.91e-0522138330587576
Pubmed

Usp12 stabilizes the T-cell receptor complex at the cell surface during signaling.

CYLD USP34 USP24

8.91e-0522138326811477
Pubmed

Global landscape of HIV-human protein complexes.

DSP PSMA1 CAPN1 UBR4 AKAP8L CUL5 RNF7 AKAP9 EIF3C

9.28e-05457138922190034
Pubmed

LRRK2 gene in Parkinson disease: mutation analysis and case control association study.

LRRK2 PINK1

9.33e-054138216157901
Pubmed

A small molecule inhibitor of the UBE2F-CRL5 axis induces apoptosis and radiosensitization in lung cancer.

CUL5 RNF7

9.33e-054138236253371
Pubmed

Leucine-Rich Repeat Kinase 2 interacts with Parkin, DJ-1 and PINK-1 in a Drosophila melanogaster model of Parkinson's disease.

LRRK2 PINK1

9.33e-054138219692353
Pubmed

Analysis of Parkinson disease patients from Portugal for mutations in SNCA, PRKN, PINK1 and LRRK2.

LRRK2 PINK1

9.33e-054138218211709
Pubmed

SAG/RBX2 is a novel substrate of NEDD4-1 E3 ubiquitin ligase and mediates NEDD4-1 induced chemosensitization.

CUL5 RNF7

9.33e-054138225216516
Pubmed

Analysis of LRRK2, SNCA, Parkin, PINK1, and DJ-1 in Zambian patients with Parkinson's disease.

LRRK2 PINK1

9.33e-054138222445250
Pubmed

DCUN1D3 activates SCFSKP2 ubiquitin E3 ligase activity and cell cycle progression under UV damage.

CAND1 DCUN1D3

9.33e-054138227542266
Pubmed

Structural imaging in the presymptomatic stage of genetically determined parkinsonism.

LRRK2 PINK1

9.33e-054138220483373
Pubmed

Interaction between the Ret finger protein and the Int-6 gene product and co-localisation into nuclear bodies.

EIF3CL EIF3C

9.33e-054138210504338
Pubmed

Systematic review and UK-based study of PARK2 (parkin), PINK1, PARK7 (DJ-1) and LRRK2 in early-onset Parkinson's disease.

LRRK2 PINK1

9.33e-054138222956510
Pubmed

The SAC domain-containing protein gene family in Arabidopsis.

INPP5F SYNJ2

9.33e-054138212805586
Pubmed

Bilateral subthalamic stimulation in Parkin and PINK1 parkinsonism.

LRRK2 PINK1

9.33e-054138218378882
Pubmed

Expression status of candidate genes in mesothelioma tissues and cell lines.

DSP THBS2

9.33e-054138225771974
Pubmed

Autosomal dominant Parkinson's disease: Incidence of mutations in LRRK2, SNCA, VPS35 and GBA genes in Brazil.

LRRK2 VPS35

9.33e-054138227777137
Pubmed

Screening PARK genes for mutations in early-onset Parkinson's disease patients from Queensland, Australia.

LRRK2 PINK1

9.33e-054138218486522
Pubmed

Identification and characterization of TSAP, a novel gene specifically expressed in testis during spermatogenesis.

POTEH POTEB

9.33e-054138217342726
Pubmed

Familial Parkinsonism and early onset Parkinson's disease in a Brazilian movement disorders clinic: phenotypic characterization and frequency of SNCA, PRKN, PINK1, and LRRK2 mutations.

LRRK2 PINK1

9.33e-054138219205068
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

SETX CAND1 INTS1 TERF2 ARMCX1 HELB JARID2 BPTF NOM1

1.13e-04469138927634302
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

CYLD DOCK4 KNTC1 USP34 SETX DSP LRSAM1 DDX1 POTEJ PPP6R2

1.26e-045881381038580884
Pubmed

An Interaction Landscape of Ubiquitin Signaling.

CYLD UBR4 USP24 DDI2 VPS36 NPLOC4 CUL5 DST PRKCI

1.36e-04481138928190767
Pubmed

SAG/ROC2/RBX2 is a HIF-1 target gene that promotes HIF-1 alpha ubiquitination and degradation.

CUL5 RNF7

1.55e-045138217828303
Pubmed

Analysis of PARK genes in a Korean cohort of early-onset Parkinson disease.

LRRK2 PINK1

1.55e-045138218704525
Pubmed

Unaltered striatal dopamine release levels in young Parkin knockout, Pink1 knockout, DJ-1 knockout and LRRK2 R1441G transgenic mice.

LRRK2 PINK1

1.55e-045138224733019
Pubmed

Relative contribution of simple mutations vs. copy number variations in five Parkinson disease genes in the Belgian population.

LRRK2 PINK1

1.55e-045138219405094
Pubmed

Genotypic and phenotypic characteristics of Dutch patients with early onset Parkinson's disease.

LRRK2 PINK1

1.55e-045138218973254
Pubmed

Methods to Study the Unique SOCS Box Domain of the Rab40 Small GTPase Subfamily.

CUL5 RNF7

1.55e-045138234453716
Pubmed

p97/VCP promotes degradation of CRBN substrate glutamine synthetase and neosubstrates.

NPLOC4 CRBN

1.55e-045138228320958
Pubmed

Genetic etiology of Parkinson disease associated with mutations in the SNCA, PARK2, PINK1, PARK7, and LRRK2 genes: a mutation update.

LRRK2 PINK1

1.55e-045138220506312
Pubmed

Cullin-5 neddylation-mediated NOXA degradation is enhanced by PRDX1 oligomers in colorectal cancer.

CUL5 RNF7

1.55e-045138233712558
Pubmed

Structural analysis of the RZZ complex reveals common ancestry with multisubunit vesicle tethering machinery.

KNTC1 NBAS

1.55e-045138220462495
Pubmed

Effect of five genetic variants associated with lung function on the risk of chronic obstructive lung disease, and their joint effects on lung function.

THSD4 GSTCD

1.55e-045138221965014
Pubmed

Genetic loci influencing natural variations in femoral bone morphometry in mice.

EIF3CL FBN1 EIF3C

1.67e-0427138311518254
Pubmed

Parkinson Disease Overview

LRRK2 VPS35 PINK1

1.67e-0427138320301402
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

LRSAM1 VPS36 USP9Y LCP1 AKAP8L RYR3 VPS13D SLC4A1AP VPS35

1.74e-04497138936774506
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

PDE2A CAND1 DSP PPP1R12B NCDN DDX1 EIF3CL SACM1L CUL5 DST APPL2 SACS VPS35 EXOC1 EIF3C PPP6R2

1.85e-0414311381637142655
Pubmed

The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.

USP34 UBR4 ARMCX1 AKAP8L JARID2 BPTF AKAP9 CRBN

1.93e-04396138826687479
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

KNTC1 INCENP PPP1R12B TERF2 AKAP8L NCDN EIF3CL TUBGCP6 NBAS FANCB SYNJ2 PRKCI EIF3C CRBN

2.11e-0411551381420360068
Pubmed

Structure and dynamics of the ASB9 CUL-RING E3 Ligase.

CUL5 RNF7

2.32e-046138232513959
Pubmed

Inhibition of a NEDD8 Cascade Restores Restriction of HIV by APOBEC3G.

CUL5 RNF7

2.32e-046138223300442
GeneFamilyAnkyrin repeat domain containing|POTE ankyrin domain containing

POTEG POTEB2 POTEJ POTEH POTEB

6.11e-09131015685
GeneFamilyNLR family

NLRP7 NLRP14 CIITA NLRP4

1.06e-05251014666
GeneFamilyPhosphoinositide phosphatases

INPP5F SACM1L SYNJ2 FIG4

2.93e-053210141079
GeneFamilyParkinson disease associated genes

LRRK2 VPS35 PINK1

8.99e-05161013672
GeneFamilyUbiquitin specific peptidases

CYLD USP34 USP24 USP9Y

2.70e-04561014366
GeneFamilyPyrin domain containing|Pyrin and HIN domain family

NLRP7 NLRP14 NLRP4

3.56e-04251013994
GeneFamilyAnkyrin repeat domain containing

PPP1R12B POTEG POTEB2 POTEJ POTEH POTEB PPP1R16A

4.17e-042421017403
GeneFamilyEF-hand domain containing|Plakins

DSP DST

8.46e-0481012939
GeneFamilyCopines

CPNE8 CPNE9

1.08e-0391012829
GeneFamilyEF-hand domain containing

EFCAB6 NOX5 CAPN1 LCP1 RYR3 DST

1.44e-032191016863
GeneFamilyATP binding cassette subfamily A

ABCA2 ABCA7

2.69e-03141012805
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

PPP1R12B AKAP9 SACS NOM1 PPP1R16A

3.47e-031811015694
GeneFamilyRing finger proteins

TRIML1 RNF152 TRIM52 RNF7 RNF38 TRIM49B

4.45e-03275101658
GeneFamilyPhosphodiesterases

PDE2A PDE3A

7.87e-03241012681
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

DOCK4 USP34 SETX CAND1 USP24 TEAD1 INPP5F JARID2 BPTF NBAS THBS2 DST AKAP9 PTPRK SACS ARHGEF10 SYNJ2 PRKCI

4.91e-0785613618M4500
CoexpressionFOROUTAN_PRODRANK_TGFB_EMT_UP

DOCK4 FHOD3 SPDL1 JARID2 FBN1 PTPRK SACS KCNMA1

5.77e-061851368M42503
CoexpressionFOROUTAN_TGFB_EMT_UP

DOCK4 FHOD3 SPDL1 JARID2 FBN1 PTPRK SACS KCNMA1

7.58e-061921368M42501
CoexpressionGSE7460_FOXP3_MUT_VS_WT_ACT_WITH_TGFB_TCONV_DN

DOCK4 AMPD1 RAMP1 AKAP8L APPL2 ARHGEF10 CARNS1 PINK1

1.02e-052001368M5705
CoexpressionGSE15330_HSC_VS_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_UP

CYLD AMPD1 CAND1 RAMP1 USP24 APPL2 CARNS1

2.26e-051621367M7005
CoexpressionFOROUTAN_INTEGRATED_TGFB_EMT_UP

DOCK4 FHOD3 FBN1 PTPRK SACS KCNMA1

3.93e-051201366M42505
CoexpressionBUSSLINGER_GASTRIC_X_CELLS

PDE2A DSP TEAD1 DST AKAP9 APPL2 KCNMA1

6.46e-051911367M40019
CoexpressionGSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_MDC_DN

USP24 SACM1L BPTF CIITA RNF38 PRKCI PLK3

7.60e-051961367M5008
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_TTD_DN

DOCK4 TEAD1 DST ARHGEF10 SYNJ2

7.76e-05841365M13008
CoexpressionIKEDA_MIR133_TARGETS_UP

CYLD RAPH1 SACM1L AKAP9

8.01e-05441364M2377
CoexpressionGSE10239_NAIVE_VS_DAY4.5_EFF_CD8_TCELL_UP

AMPD1 PDE2A RAMP1 TEC AKAP8L APPL2 KCNMA1

8.36e-051991367M3071
CoexpressionGSE14769_40MIN_VS_360MIN_LPS_BMDM_UP

PLEKHB2 LRSAM1 TEC SACM1L CRYGD PRKCI DHTKD1

8.63e-052001367M3514
CoexpressionGSE5679_CTRL_VS_PPARG_LIGAND_ROSIGLITAZONE_TREATED_DC_DN

ZNF862 INPP5F RFX3 AKAP8L RYR3 CARNS1 PINK1

8.63e-052001367M6554
CoexpressionIKEDA_MIR133_TARGETS_UP

CYLD RAPH1 SACM1L AKAP9

8.76e-05451364MM929
CoexpressionWANG_LMO4_TARGETS_DN

PLEKHB2 PDE3A UBR4 RNF7 AKAP9 PTPRK SLC4A1AP GSTCD EXOC1

1.16e-043611369M12674
CoexpressionAtlasDevelopingLowerUrinaryTract_P1_bladder_J_emap-30374_k-means-cluster#2_top-relative-expression-ranked_500

PDK4 PPP1R12B FHOD3 TEAD1 RYR3 THBS2 KCNMA1

4.63e-061051347gudmap_developingLowerUrinaryTract_P1_bladder_J_500_k2
ToppCell3'_v3-bone_marrow-Myeloid_Mac-Erythrophagocytic_macrophages|bone_marrow / Manually curated celltypes from each tissue

OTOA CPNE9 PDK4 LRSAM1 KLHL3 TCAIM CIITA KCNMA1

9.57e-081801388daf69a548ed7c6f285a6adcff00f99aa22f9d6a5
ToppCellLPS-antiTNF-Epithelial_airway-Mes-Epi-like|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

STARD4 INCENP SLC44A4 NCDN RYR3 ZNF77 GPRASP2

8.16e-0716413874307b002fb41ddfc7ab8a6bca66a60942c250052
ToppCellLPS-antiTNF-Epithelial_airway-Mes-Epi-like-Airway|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

STARD4 INCENP SLC44A4 NCDN RYR3 ZNF77 GPRASP2

8.16e-0716413871d84aa5b925f502ee9c5fa39714490f613a58028
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TICRR IFT140 PDE2A PDE3A HYAL1 KLHL3 TCAIM

1.12e-0617213878a6a2b4c6654bc976e60a02d0e7303a9071ed55f
ToppCellNS-moderate-d_16-33-Epithelial-Ionocyte|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

RNF152 PPP1R12B FHOD3 TNFRSF11B DST CSPG5 ATP6V0A4

1.52e-0618013878af8b4af2dc72223ac71fc027e0d4280c5dd81f8
ToppCell5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte-Ionocyte_L.0.7.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RNF152 DSP PPP1R12B FHOD3 DST CSPG5 ATP6V0A4

1.58e-06181138740df0afcb6848202da54670e84f22d7c3a515d01
ToppCell5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RNF152 DSP PPP1R12B FHOD3 DST CSPG5 ATP6V0A4

1.58e-0618113872b53a65ca5616a7b9f64232c3e0b7212d1e2f063
ToppCell5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RNF152 DSP PPP1R12B FHOD3 DST CSPG5 ATP6V0A4

1.58e-0618113876aef84616e8d2faf54b7e9e6cd02f33c3066dabc
ToppCell5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RNF152 DSP PPP1R12B FHOD3 DST CSPG5 ATP6V0A4

1.58e-06181138740d3829ae4aaf81e8616c3499ff8933137fc1cc4
ToppCellcritical-Epithelial-Ionocyte|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

RNF152 PPP1R12B TNFRSF11B DST CSPG5 ATP6V0A4 KCNMA1

1.76e-06184138758d36577eff814d46d72f031f3533d71549e3d6e
ToppCellCOVID-19-Heart-CM_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

THSD4 PDE3A RAMP1 PDK4 PPP1R12B FHOD3 KBTBD12

1.83e-061851387549eeb521c3985bff396ea0f202db21822efa51f
ToppCellCOVID-19-Heart-CM_1|Heart / Disease (COVID-19 only), tissue and cell type

THSD4 PDE3A RAMP1 PDK4 PPP1R12B FHOD3 KBTBD12

2.59e-061951387f1ef50331eda8f1239dba6ea970df4eaccf032f1
ToppCellCOVID-19-Heart-CM_2|Heart / Disease (COVID-19 only), tissue and cell type

THSD4 PDE3A RAMP1 PDK4 PPP1R12B FHOD3 DST

2.59e-06195138775fc81bddb246dca3b437fb60827b1d4fe416405
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_cycling|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KNTC1 TICRR INCENP CCDC150 SPDL1 FANCB APOLD1

2.68e-06196138773f951f7712e0aa3323676b9a4b7944d21d347c4
ToppCellsevere-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CYLD USP34 PCDHGA11 USP24 RFX3 HELB AKAP9

2.77e-06197138757ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell(00)_Basal-(2)_GFP_FOXI1|(00)_Basal / shred by cell type by condition

SETX PPP1R12B BPTF METTL5 AKAP9 SYNJ2 PRKCI

2.96e-06199138719674e1eaeb51e4196d847cb62aa437c852951d3
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar-Dividing_AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KNTC1 TICRR INCENP CCDC150 FANCB APOLD1 CSPG5

2.96e-0619913871d5a3366474c17e3df0ba5cf11b586655529e9bd
ToppCellNS-critical-d_16-33-Epithelial-Ionocyte|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

RNF152 PPP1R12B DST CSPG5 ATP6V0A4 KCNMA1

1.42e-0516813866a233045638cb83dab64789b996b7598c325001e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KNTC1 TICRR INCENP LCP1 FANCB APOLD1

1.73e-0517413867b318796728001c17b4043d2b033330c7be40c78
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

THSD4 CPNE9 ZBTB7C LRRK2 RYR3 PTPRK

1.73e-051741386ae363ce736fc8af439f3ad594d7bc2e344db80d4
ToppCellNS-moderate-d_0-4-Epithelial-Ionocyte|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

RNF152 PPP1R12B FHOD3 DST CSPG5 KCNMA1

1.79e-051751386a1e0a15c69211d6db2edeb101476f0f6e08b90c8
ToppCellNS-moderate-d_07-13-Epithelial-Ionocyte|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

RNF152 PPP1R12B DST CSPG5 ATP6V0A4 KCNMA1

1.90e-05177138699500aed584f793aaf308f8afbf5d1c6a9b4ee55
ToppCellNS-critical-LOC-Epithelial-Ionocyte|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

RNF152 DSP PPP1R12B DST CSPG5 ATP6V0A4

2.03e-05179138665a96bee7bc28f5bfc20f0fd92bcc0ab2eb5e06c
ToppCellNS-critical-d_07-13-Epithelial-Ionocyte|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

RNF152 PPP1R12B TNFRSF11B DST CSPG5 KCNMA1

2.30e-051831386ba43bca2b45be1008eebd3f033cecb061fb3a966
ToppCelldroplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CPNE9 ZBTB7C TEAD1 KLHL3 FBN1 DST

2.37e-051841386f506d0ee48f39d6f59f19554217dfdf0987cc405
ToppCelldroplet-Lung-30m-Endothelial-arterial_endothelial|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CPNE9 ZBTB7C TEAD1 KLHL3 FBN1 DST

2.37e-0518413868bcb1c4bc8ffef74338cdade926a94711de93c64
ToppCellControl-T_cells-Cycling_NK/T_cells|Control / group, cell type (main and fine annotations)

KNTC1 TICRR INCENP CCDC150 FANCB APOLD1

2.44e-0518513869766216b41ee62bbac4caa25cb98ec5627a24075
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A LRRK2 ARMCX1 TUBGCP6 SYNJ2 EXOC1

2.44e-051851386bdd2e6cb20294b39a9d856004bf57ba69cf877e2
ToppCellnormal_Lymph_Node-B_lymphocytes-GC_B_cells_in_the_LZ|B_lymphocytes / Location, Cell class and cell subclass

RAMP1 LCP1 TERF2 KCNMA1 NLRP4 STAG3

2.59e-051871386457eb3791a8c5458d81833e0701ac5a9bfdee2bf
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KNTC1 TICRR INCENP CCDC150 FANCB APOLD1

2.59e-0518713869351fa87b69a951af85b10bf91fe9b1cce8c0517
ToppCellmoderate-Epithelial-Ionocyte|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

RNF152 PPP1R12B TNFRSF11B DST CSPG5 ATP6V0A4

2.59e-0518713863e3fe2d5712a0ac477cddefe56705d4b8d8f7eac
ToppCell-Unknown-Endothelial-Myofibroblast| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

THSD4 LRRK2 USP24 TCAIM KCNMA1 RNF38

2.67e-0518813866468fa95ad0395395301115286f2d8c0df5d3882
ToppCell-Unknown-Endothelial| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

THSD4 LRRK2 USP24 TCAIM KCNMA1 RNF38

2.67e-0518813867a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell-Unknown| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

THSD4 LRRK2 USP24 TCAIM KCNMA1 RNF38

2.67e-0518813869cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCellCOPD-Stromal-SMC|Stromal / Disease state, Lineage and Cell class

PDE3A RNF152 RAMP1 PDK4 APOLD1 CARNS1

2.67e-0518813869ffef4b01d0ddd6913c9ed6be79aeaaabd5e41ed
ToppCellRV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

THSD4 PDE3A PDK4 PPP1R12B FHOD3 KBTBD12

2.75e-0518913865e80c47f63980904c4c1ff02c201b67b456a0974
ToppCellmoderate-Epithelial-Ionocyte|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

PPP1R12B TNFRSF11B DST CSPG5 ATP6V0A4 KCNMA1

2.75e-0518913866011b747e27d61d222380a7bffdd921a68e9b657
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3A RAMP1 PPP1R12B THBS2 DST KCNMA1

2.84e-0519013862e88e366d377d74deb53a4ea870973ce5c6532e8
ToppCellcritical-Epithelial-Ionocyte|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

RNF152 PPP1R12B TNFRSF11B DST CSPG5 KCNMA1

2.84e-05190138605a2c3549b68f49081723bf35db14974274419d5
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3A RAMP1 PPP1R12B THBS2 DST KCNMA1

2.84e-0519013860028f886c789ba238c031eae5d96acaed4af8c25
ToppCelldroplet-Lung-1m-Hematologic-myeloid-alveolar_macrophage|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PLEKHB2 RAMP1 CLEC6A CAPN1 LCP1 DST

2.84e-051901386da58227565ad6a690828dd8554dd3670222f8582
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 PDE3A RAMP1 THBS2 FBN1 KCNMA1

2.84e-05190138670c86dd454afb21d4a85db56c5f369d4b342bc97
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

THSD4 PDE3A CPNE9 ZBTB7C LRRK2 PTPRK

2.84e-0519013861bbbf0ce222e51f9fd2daca0c18d3965fd4efd31
ToppCellRV-06._Ventricular_Cardiomyocyte_II|RV / Chamber and Cluster_Paper

THSD4 PDE3A PDK4 PPP1R12B FHOD3 DST

2.84e-051901386fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCellPSB-critical-LOC-Epithelial-Ionocyte|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

RNF152 DST CSPG5 ATP6V0A4 KCNMA1 TEC

2.92e-0519113868f4637e801554e2343b974fe7794f01dd2151418
ToppCellLV-06._Ventricular_Cardiomyocyte_II|LV / Chamber and Cluster_Paper

THSD4 PDE3A PDK4 PPP1R12B FHOD3 DST

2.92e-05191138625f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

THSD4 PDE3A RAMP1 ZBTB7C PPP1R12B KCNMA1

2.92e-05191138608042952431ca1a6fd7dfc13f36eb28643979598
ToppCellhuman_hepatoblastoma-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

DSP JARID2 BPTF AKAP9 PTPRK SYNJ2

3.01e-051921386916fbec1c7ab7969bda711886ac88e877e30c280
ToppCellCOVID-19-Heart-CM_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

THSD4 PDE3A RAMP1 PDK4 PPP1R12B FHOD3

3.10e-051931386dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

USP34 CAND1 DDI2 BPTF AKAP9 PTPRK

3.10e-051931386abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellhuman_hepatoblastoma|World / Sample and Cell Type and Tumor Cluster (all cells)

DSP RFX3 JARID2 BPTF AKAP9 SYNJ2

3.10e-051931386e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCellCOPD-Myeloid-Macrophage|World / Disease state, Lineage and Cell class

DOCK4 PDK4 LRRK2 JARID2 CIITA KCNMA1

3.19e-0519413867d682408e9a6239a4e47befc9376e760cc3d133a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3A RAMP1 PPP1R12B THBS2 FBN1 KCNMA1

3.19e-051941386ebb038f94f49f5c655578d1b018676e10c6b7e3c
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

USP34 USP24 USP9Y HELB BPTF AKAP9

3.67e-051991386f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellCOPD-Myeloid-Macrophage|Myeloid / Disease state, Lineage and Cell class

DOCK4 RAPH1 PDK4 JARID2 CIITA KCNMA1

3.67e-0519913861cf1b2d6debf9e3389f1829dcaa2857e9533a080
ToppCellCOPD-Myeloid-Macrophage|COPD / Disease state, Lineage and Cell class

DOCK4 RAPH1 PDK4 JARID2 CIITA KCNMA1

3.67e-0519913864b9c53fb4f44190d2f6ad4d52b13be01ebe4955e
ToppCell(07)_Ionocytes|World / shred by cell type by condition

PLEKHB2 PDK4 PPP1R12B CSPG5 ATP6V0A4 KCNMA1

3.67e-0519913868194777d367405a7840787e977854b5c07e3bd6b
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

THSD4 USP34 PPP1R12B FOCAD NBAS KCNMA1

3.67e-05199138694b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellControl_saline-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|Control_saline / Treatment groups by lineage, cell group, cell type

THSD4 PPP1R12B FHOD3 FBN1 CSPG5 KCNMA1

3.78e-052001386c5e051f1aac8dda376c342a9932785a23450e073
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated|COVID-19_Mild / Disease, condition lineage and cell class

SETX USP24 USP9Y LCP1 EIF3CL EIF3C

3.78e-0520013862281debd86e5d92e8fe0397aec9ef670800f7471
ToppCellRV-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

THSD4 PDE3A PDK4 PPP1R12B FHOD3

3.92e-0512213851cb1dd03b2aaedbe04f3ed907568c3b7f54767b3
ToppCellfacs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l28|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

THSD4 CPNE8 KLHL3 ATP6V0A4 KCNMA1

8.35e-051431385b4ed3855652fdf32f97cb7c18cab4f4f4c24d5c7
ToppCell390C-Fibroblasts-Fibroblast-G-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

INCENP FANCB DST CCL28 TEC

1.11e-041521385ebce79e106bf1d84241f8dd3496ff1771f9666be
ToppCell390C-Fibroblasts-Fibroblast-G|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

INCENP FANCB DST CCL28 TEC

1.11e-0415213854a749d1b6d35fd55a8c42d7bd04b6ff5b11ce781
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Monocytic-Nonclassical_Monocyte|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

OTOA ZBTB7C LRSAM1 VPS36 KCNMA1

1.22e-04155138596c48d835725eac1bc7926f4cddecb67c29b7d7c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_low-phase|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TICRR RAMP1 CCL28 APOLD1 NLRP4

1.33e-041581385d72d6527dc50207ddbada262460d3c4bac249a19
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L4|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CPNE8 CPNE9 LRRK2 FHOD3 PTPRK

1.54e-0416313851e8ab00ecc2d2ba35aa6745c0ed38663e26312e8
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLEKHB2 KNTC1 FANCB CCL28 KBTBD12

1.54e-0416313858dc0128eeede933537e3bcc5d6ec0322711552f3
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L4-L4_IT_VISp_Rspo1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CPNE8 CPNE9 LRRK2 FHOD3 PTPRK

1.54e-041631385431221a41d396b09170476179590eaf8a55266d8
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLEKHB2 KNTC1 FANCB CCL28 KBTBD12

1.54e-041631385fd243ca223079033be480a24817a399f281fa4d4
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Degenerative_Cortical_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RNF152 DSP TAS2R1 ATP6V0A4 KBTBD12

1.59e-04164138583141be8dfed85511ea6afda7c76ff4b6b5ef021
ToppCellNS-control-d_0-4-Epithelial-Ionocyte|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DOCK4 PPP1R12B TNFRSF11B CSPG5 KCNMA1

1.68e-0416613856d9fb239f69ba519844f593c00d515e1aac4ff50
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

THSD4 HYAL1 TEAD1 PTPRK GSTCD

1.68e-04166138589e2b8453180983533faccb4275867861876d7ee
ToppCellP15-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

DSP PPP1R12B ABCA7 TUBGCP6 CMTR2

1.73e-0416713855c3d0763f73628c71c71f9883556bb4f1639f3cc
ToppCelldroplet-Heart-nan-24m-Mesenchymal-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTC34 ABCA7 SPDL1 APOLD1 PLK3

1.73e-041671385a35ace2c722936d2a3e1f0826e5b6ec6b1340d2b
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

THSD4 PDE3A ZBTB7C THBS2 NLRP4

1.93e-0417113854ede831aed364cb5271f49a8b09bb6d0452f9b35
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Microglia/Mac|metastatic_Lymph_Node / Location, Cell class and cell subclass

KNTC1 PDK4 ZNF862 ABCA7 KLHL3

1.98e-041721385f673a2e697b46e7cfa4186cb3fb2b98e3c83703e
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel-D122|Adult / Lineage, Cell type, age group and donor

PDE2A RNF152 DSP KLHL3 FBN1

2.04e-041731385dba09ba9748871e38a16449d500ae4d7b405c42f
ToppCellfacs-Marrow-KLS-3m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KNTC1 PPP1R12B NCDN NBAS SLC4A1AP

2.04e-0417313858bffd512a4e561e23cc04478e2ca6fd5d3771fe4
ToppCellfacs-Marrow-KLS-3m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KNTC1 PPP1R12B NCDN NBAS SLC4A1AP

2.04e-0417313853e3c61468e703330788a10d850ef41a85680f86d
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PDE3A RAMP1 PPP1R12B SACS KCNMA1

2.04e-041731385cb6389536195443633adb06e5f1b7483530773d1
ToppCellfacs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l28|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AMPD1 RNF152 TUBGCP6 ATP6V0A4 GSTCD

2.15e-041751385aa168aeb9ad71aa6c0c28a0657c9eb92a0b28183
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KNTC1 TICRR INCENP FANCB APOLD1

2.15e-041751385876cea684faf42ff3eb4623ad6d7a1fb1276ee02
ToppCellCOVID-19-Heart-CM_3|COVID-19 / Disease (COVID-19 only), tissue and cell type

PDE3A RAMP1 PDK4 FHOD3 KBTBD12

2.20e-0417613859df7a124ebafb0087da0cda133a394275d7bed81
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

THSD4 CPNE9 ZBTB7C LRRK2 PTPRK

2.20e-04176138540993c41c1017b53039a337174fc56632b278609
ToppCell368C-Epithelial_cells-Epithelial-B_(AT2)-|368C / Donor, Lineage, Cell class and subclass (all cells)

DSP LRRK2 CCL28 ATP6V0A4 TEC

2.26e-041771385ac8f774596068e66c0a9ea8a318be0ce5f5df834
ToppCell368C-Epithelial_cells-Epithelial-B_(AT2)|368C / Donor, Lineage, Cell class and subclass (all cells)

DSP LRRK2 CCL28 ATP6V0A4 TEC

2.26e-041771385d9c4a93b0e04a13bf39992dd1c1ec8df2c5f89fe
ToppCelldroplet-Lung-LUNG-30m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE3A CPNE9 ZBTB7C KLHL3 DST

2.38e-041791385a09647750eba9d93c5efc1db3b555fefb5eec7b5
ToppCellCOVID-19-Heart-VSMC|Heart / Disease (COVID-19 only), tissue and cell type

PDE3A RNF152 ZBTB7C PDK4 KCNMA1

2.38e-041791385a69ad6912b5c10bb9f9d800f724c792341e9bab1
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L3_RORB_CARTPT|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

THSD4 ZBTB7C TEC RFX3 PTPRK

2.45e-0418013855e78b29fa1cbdcf502fee3577e5b45766b90d1dc
ToppCellLPS-IL1RA-Endothelial-Endothelial-FOXM1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KNTC1 TICRR INCENP CCDC150 SPDL1

2.45e-041801385334e2b1f6eb7d4ece20b1c7b02107863f913237f
ToppCellControl-Fibroblasts-Airway_smooth_muscle|Control / group, cell type (main and fine annotations)

THSD4 PDE3A RAMP1 THBS2 KCNMA1

2.45e-041801385d0de12749ef0f51f0931c6e7b9b99966bdbc3ec1
ToppCellCOVID-19-Heart-CM_+_EC_+_Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

PDE3A RAMP1 PDK4 FHOD3 KBTBD12

2.51e-041811385719eb532453ab7cd7893726885bc75d74a10b21e
ToppCellPericytes-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

PDE3A RAMP1 THBS2 FBN1 CARNS1

2.51e-041811385ff445a8e56522e57e27405184d123cf905caf8cc
ToppCellRV|World / Chamber and Cluster_Paper

THSD4 PDK4 FHOD3 AKAP9 KBTBD12

2.51e-041811385bbe1e6e59d8889bd37d6e8303116cbdcafca7236
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RAMP1 PPP1R12B FHOD3 DST KCNMA1

2.51e-041811385beb2771820956be8b190c0088ae3c4efdb53c897
ToppCellCOVID-19-Heart-CM_3|Heart / Disease (COVID-19 only), tissue and cell type

THSD4 PDE3A PDK4 FHOD3 TNFRSF11B

2.57e-041821385287fcc3897ae08841f6f85ae6c9cef16f75b1dd1
ToppCellcellseq-Epithelial-Epithelial_Neuro-Secretory-Ionocyte|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

RNF152 PPP1R12B CSPG5 ATP6V0A4 KCNMA1

2.57e-0418213856e7dac78dc030f74e546b9f6db07556e9bb13ac2
ToppCellcellseq-Epithelial-Epithelial_Neuro-Secretory-Ionocyte-Ionocyte|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

RNF152 PPP1R12B CSPG5 ATP6V0A4 KCNMA1

2.57e-041821385cd972d30519db706477c6b0c901165b81b74abed
ToppCellCOVID-19-Heart-CM_4|COVID-19 / Disease (COVID-19 only), tissue and cell type

PDE3A RAMP1 PDK4 FHOD3 KBTBD12

2.64e-0418313852902b6e8aa9a6f62bc1a792c971ab7f651a8e676
DiseaseCharcot-Marie-Tooth Disease

SETX LRSAM1 FIG4

1.79e-05121303C0007959
Diseasetyrosine-protein kinase TEC measurement

TEC TEC

1.15e-0441302EFO_0020830
DiseaseParkinson disease

LRRK2 VPS35 PINK1

1.21e-04221303cv:C0030567
Diseaseearly-onset Parkinson's disease (implicated_via_orthology)

SYNJ2 PINK1

2.86e-0461302DOID:0060894 (implicated_via_orthology)
DiseaseHereditary Motor and Sensory Neuropathy Type I

LRSAM1 FIG4

5.30e-0481302C0751036
DiseaseRoussy-Levy Syndrome (disorder)

LRSAM1 FIG4

5.30e-0481302C0205713
DiseaseCharcot-Marie-Tooth Disease, Type Ib

LRSAM1 FIG4

5.30e-0481302C0270912
DiseaseCharcot-Marie-Tooth Disease, Type Ia (disorder)

LRSAM1 FIG4

5.30e-0481302C0270911
Diseasemosquito bite reaction itch intensity measurement, mosquito bite reaction size measurement

EFCAB6 SLC44A4 FOCAD TNNI3K PTPRK EXOC1 PINK1

6.47e-043281307EFO_0008377, EFO_0008378
Disease1-ribosyl-imidazoleacetate measurement

CARNS1 DHTKD1

6.80e-0491302EFO_0800034
DiseaseNephroblastoma

DDX1 NBAS

8.47e-04101302Orphanet_654
Diseaseaortic valve stenosis (is_marker_for)

TNFRSF11B JARID2

1.03e-03111302DOID:1712 (is_marker_for)
DiseaseHereditary Motor and Sensory-Neuropathy Type II

LRSAM1 FIG4

1.46e-03131302C0270914
DiseaseDrug habituation

THSD4 FHOD3 DDX1 APPL2

1.70e-031151304C0013170
DiseaseDrug abuse

THSD4 FHOD3 DDX1 APPL2

1.70e-031151304C0013146
DiseasePrescription Drug Abuse

THSD4 FHOD3 DDX1 APPL2

1.70e-031151304C4316881
DiseaseSubstance-Related Disorders

THSD4 FHOD3 DDX1 APPL2

1.70e-031151304C0236969
DiseaseDrug Use Disorders

THSD4 FHOD3 DDX1 APPL2

1.70e-031151304C0013222
DiseaseDrug Dependence

THSD4 FHOD3 DDX1 APPL2

1.70e-031151304C1510472
DiseaseSubstance Dependence

THSD4 FHOD3 DDX1 APPL2

1.70e-031151304C0038580
DiseaseSubstance Use Disorders

THSD4 FHOD3 DDX1 APPL2

1.70e-031151304C0038586
DiseaseOrganic Mental Disorders, Substance-Induced

THSD4 FHOD3 DDX1 APPL2

1.70e-031151304C0029231
DiseaseSubstance abuse problem

THSD4 FHOD3 DDX1 APPL2

1.76e-031161304C0740858
Diseasequinate measurement

NOX5 LRRK2

1.95e-03151302EFO_0021167
Diseaseretinal layer thickness measurement

NPLOC4 NBAS CRBN

2.38e-03601303EFO_0600002
DiseaseAmyotrophic lateral sclerosis

SETX FIG4

2.51e-03171302cv:C0002736
Diseaseprogression free survival, ovarian carcinoma

FHOD3 NBAS

2.81e-03181302EFO_0001075, EFO_0004920
Diseasecystathionine measurement

TEC TEC

3.14e-03191302EFO_0010474
Diseaseosteoporosis (implicated_via_orthology)

TNFRSF11B CIITA

3.14e-03191302DOID:11476 (implicated_via_orthology)
Diseasepulse pressure measurement

THSD4 USP34 PDE3A RAPH1 DDI2 FHOD3 TEC LCP1 TERF2 THBS2 FBN1 CMTR2 TRIM49B TEC

3.37e-03139213014EFO_0005763
Diseasesusceptibility to chronic sinus infection measurement

CAND1 CIITA NLRP4

3.40e-03681303EFO_0008419
Diseaselymphocyte count, response to vaccine

NBAS KCNMA1

4.20e-03221302EFO_0004587, EFO_0004645

Protein segments in the cluster

PeptideGeneStartEntry
IECLMSDQECVKRNR

AKAP9

2331

Q99996
KVIECFNVESRILCM

ARHGEF10

946

O15013
VNMCRIQRADGDCDL

CCL28

46

Q9NRJ3
NSVEALMECCVNALV

CUL5

256

Q93034
RCESIITDFQVMCVA

CSPG5

411

O95196
DTINCDQFSRLLCDM

CIITA

71

P33076
QLETISENIRLFECM

CMTR2

371

Q8IYT2
QRLRCELDIMNKCTS

CRBN

306

Q96SW2
EQEAQMVQAAFRCCL

CARNS1

651

A5YM72
TCDMCEVARNSVLQC

AMPD1

676

P23109
DFDNFVCCLVRLETM

CAPN1

671

P07384
CRIERFLQMCDSAEE

DHTKD1

711

Q96HY7
CAALVSQEQCTLMAE

BPTF

271

Q12830
ILEEGMERFCNDLCV

DCUN1D3

106

Q8IWE4
EECEALCSRLAIMVN

ABCA7

1986

Q8IZY2
DRMVERIQFVCSLCK

AKAP8L

381

Q9ULX6
AICRVQVMDACLRCQ

RNF7

51

Q9UBF6
LRELCLTQFQVDMEA

RAMP1

36

O60894
MADRNKEVLLEECFC

RAPH1

376

Q70E73
KRFCQCEQRSLEQLM

ITPKC

431

Q96DU7
LCETVSSCFLNMELL

PCDHGA11

96

Q9Y5H2
AVQCQEDECVLMLLE

POTEB2

176

H3BUK9
CLNFDCSFIAVLMLR

NOX5

276

Q96PH1
VAVVQDAFECSRMLC

PDK4

201

Q16654
ATCQDQMREILSCLE

APOLD1

156

Q96LR9
RCFQMLNSLECVEIL

OTOA

166

Q7RTW8
TLDLNRVLDEMRCQC

KRT40

251

Q6A162
RVLDEMRCQCETVLA

KRT40

256

Q6A162
CNEVRDMCSFDNEQL

PRKCI

51

P41743
DLRAVNINLCDMCVI

KCNMA1

911

Q12791
MELGIQECTRCEQSL

NCDN

341

Q9UBB6
CFQTREILDAMNRDC

GK3P

401

Q14409
LLELCDQKLMEFLCN

INCENP

11

Q9NQS7
TNLQRLMSSAEECCR

INTS1

2086

Q8N201
QASECVVCLEREAQM

LRSAM1

671

Q6UWE0
VVCLEREAQMIFLNC

LRSAM1

676

Q6UWE0
RCQNVAEDMDIQLCA

DST

2616

Q03001
RQCCFNMLTELVNVL

CAND1

451

Q86VP6
MDQAIIFCRTKIDCD

DDX1

506

Q92499
CSREMLNLLCSNALF

LIPF

246

P07098
CMLQQAERLGCRQFV

LCP1

336

P13796
MLFLANLECETLCQA

PINK1

556

Q9BXM7
LEDIEIFALFISCMC

PDE2A

681

O00408
NDRLLVCQMCIKLAD

PDE3A

936

Q14432
QVSNQCMALVRDECL

NPLOC4

386

Q8TAT6
ACDQNNSIMVECLLL

LRRK2

716

Q5S007
AVELSRQCQMDDCGI

KNTC1

1161

P50748
REECLCHSMIQETLQ

TUBGCP6

166

Q96RT7
LSEQCCEYISEMLLR

NLRP4

791

Q96MN2
ARLLCNFMRQECLDS

PSMA1

81

P25786
LMAIALECIYTCERN

NBAS

991

A2RRP1
IALVATNLICDMRFC

OR10T2

156

Q8NGX3
SKFCCTVLLQIMERE

FANCB

591

Q8NB91
EFELTNIDMVQCDVC

METTL5

96

Q9NRN9
NIDMVQCDVCLLSNR

METTL5

101

Q9NRN9
CLDCINELMDILFAN

EIF3C

401

Q99613
KCLDCINELMDILFA

EIF3CL

401

B5ME19
QMIEFTEDCSCLQDR

CRYGD

101

P07320
NCEFLVNRMCRLESL

CCDC150

96

Q8NCX0
QNEEEFRCCIQELLM

DOCK4

726

Q8N1I0
CFQTREILEAMNRDC

GK2

401

Q14410
NEMNCCRTLRELEIQ

EFCAB6

151

Q5THR3
CVDCLDRTNTAQFMV

FIG4

486

Q92562
DRLFCVDIDECSIMN

FBN1

1191

P35555
QTMCLDINECERDAC

FBN1

1886

P35555
IQELLQNCSDCLMRA

DSP

71

P15924
QNCSDCLMRAELIVQ

DSP

76

P15924
EELSNCRDIATMQLC

CPNE9

141

Q8IYJ1
CRDIATMQLCANKLD

CPNE9

146

Q8IYJ1
LQDNLCQMERRCKAS

FHOD3

1161

Q2V2M9
EECEALCTRLAIMVN

ABCA2

2246

Q9BZC7
LIQDLDNCSVMAVDC

APPL2

321

Q8NEU8
AASLLQLMDVRQNCC

KLHL3

126

Q9UH77
QLMDVRQNCCDFLQS

KLHL3

131

Q9UH77
MCVDTLFLCFLEDLE

SLC44A4

661

Q53GD3
IEACTNAADALLQCM

EXOC1

301

Q9NV70
LEDQAQMAVEFKCRC

HYAL1

406

Q12794
SQACAERCNIMRLVD

DDI2

261

Q5TDH0
CQNMELFAVLCIETS

CYLD

856

Q9NQC7
RSNCMDCLDRTNVIQ

SACM1L

386

Q9NTJ5
EGIFRVNCMDCLDRT

INPP5F

451

Q9Y2H2
VNCMDCLDRTNVVQA

INPP5F

456

Q9Y2H2
NCRNICNITTLDEEM

SACS

3751

Q9NZJ4
QCMCLVDLDRARAAE

GSTCD

591

Q8NEC7
ESRRELLEQIADCCM

IFT140

1186

Q96RY7
EELNCCRDAVLMQFC

CPNE8

151

Q86YQ8
AFCQCESLLQLMTDL

HELB

276

Q8NG08
LLMKSLDALENCCFD

FOCAD

1116

Q5VW36
DFLCRQQCMEELVSL

PPP6R2

46

O75170
MDCDVINRIFRICNL

PTPRK

1306

Q15262
FCDINILAMFCNENR

PANX2

341

Q96RD6
CELDLACFFRLINEM

JARID2

651

Q92833
RNTMLLCDADCVDII

KBTBD12

236

Q3ZCT8
MSELRLCCDLLVQQV

PLEKHA8P1

1

O95397
SIQMVDCCKRLLEQS

TCAIM

446

Q8N3R3
TLCVVCMCDFESRQL

RNF38

461

Q9H0F5
MDCINIRTGQECRDT

PLEKHB2

51

Q96CS7
METLSQDSLLECQIC

RNF152

1

Q8N8N0
TLRMNCLDCLDRTNT

SYNJ2

381

O15056
FSRDVLLSMCQDVCE

TEC

461

P42680
VCQCDDNMVQRLETD

RFX3

541

P48380
AVQCQEDECVLMLLE

POTEB

176

A0A0A6YYL3
NLNMIETFICQVCEE

GPRASP2

671

Q96D09
AVQCQEDECALMLLE

POTEJ

176

P0CG39
CCIDDFREMVQQLLE

PPP1R16A

111

Q96I34
RMLESLSCECEAIKQ

SPDL1

71

Q96EA4
ELCVEALCRMEQANC

SETX

131

Q7Z333
QMLSLENCRLTEASC

NLRP7

821

Q8WX94
EREIIHVLMDCCLQE

NOM1

686

Q5C9Z4
VCDDTMVCRLDSAVQ

ARMCX1

291

Q9P291
DVICETRRNSICEMN

CLEC6A

191

Q6EIG7
IMCSANCAILLFINE

TAS2R1

76

Q9NYW7
LARLCSQMEARQKEC

TMEM95

31

Q3KNT9
MQTLQEEAVCAICLD

TRIM52

11

Q96A61
VESALCALRNCIAFM

PLK3

431

Q9H4B4
MNNLLCCALVFLDIS

TNFRSF11B

1

O00300
DVMLETCRNLASLDC

ZNF77

31

Q15935
VRECQLQVFLRLEMC

TICRR

716

Q7Z2Z1
ECCMAILLSQIVFIE

VPS36

56

Q86VN1
SSLRDRMVAFCELCQ

STAG3

771

Q9UJ98
RMVAFCELCQSCLSD

STAG3

776

Q9UJ98
RCVDILELCEQEDLM

RYR3

1541

Q15413
VNCRDALAQEYLMEC

VPS35

251

Q96QK1
CREAASLVEDLTQMC

ZSCAN1

106

Q8NBB4
NFCENLALIMCERTH

ZNF322

51

Q6U7Q0
RQLAQEQFFLMCTRC

USP9Y

1331

O00507
IMNEEQTALFCSACR

ZNF862

151

O60290
LMENLREELTCFICL

TRIML1

6

Q8N9V2
RSEEMCLSQLFLQVE

ATP6V0A4

6

Q9HBG4
ARMLEIQCIVNVCLE

ZBTB7C

111

A1YPR0
SQCMEYFDLRCQLLD

USP24

1506

Q9UPU5
LDILENFEENCCVMR

STARD4

86

Q96DR4
ANSDIFLCEILRSMC

TRIM49B

296

A6NDI0
MCENCADLVEVLNEI

USP34

1

Q70CQ2
CERSCEELGNMVQEL

THBS2

266

P35442
VTNRDTQETLLCMAC

TEAD1

391

P28347
EVRCLSDDMTLSNLC

THSD4

936

Q6ZMP0
ACNEQQRTTMILLCE

UBR4

2221

Q5T4S7
SDVDMFCREVSILCQ

TNNI3K

501

Q59H18
TKAVQCREDECALML

POTEG

211

Q6S5H5
VQCQEDECALMLLEH

POTEH

251

Q6S545
TARMFLLRGQCCLEE

TTC34

511

A8MYJ7
MQCLSRIEEGENLDC

TERF2

146

Q15554
CLLDCVVVDLQDMDI

VPS13D

2151

Q5THJ4
LQDLELMGCVLTNAC

NLRP14

931

Q86W24
AMIQCSLEACRILDT

SLC4A1AP

426

Q9BWU0
CSILAEALCDMDIRN

PPP1R12B

266

O60237