Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	retrograde trans-synaptic signaling by trans-synaptic protein complex	NLGN1 TENM2 CADM1	2.10e-06	5	124	3	GO:0098942
GeneOntologyBiologicalProcess	trans-synaptic signaling by trans-synaptic complex	NLGN1 TENM2 CADM1	3.38e-05	11	124	3	GO:0099545
GeneOntologyBiologicalProcess	heart development	COL3A1 EPHB4 TMEM67 SIN3B NRAP HCN4 DNAAF4 NTRK3 CEP290 JPH2 PDCD4 NPHP3 PKD2 FHL2 HECTD1	4.99e-05	757	124	15	GO:0007507
MousePheno	decreased susceptibility to autoimmune diabetes	HLA-H PDCD4 IFNGR2 CD86 MERTK	1.90e-05	45	103	5	MP:0004804
Domain	Ig_I-set	FCRL2 NTRK2 NTRK3 OBSCN CNTN6 CADM1 PTPRK SIGLEC6 IL1RL1 MERTK SDK1	7.82e-08	190	128	11	IPR013098
Domain	I-set	FCRL2 NTRK2 NTRK3 OBSCN CNTN6 CADM1 PTPRK SIGLEC6 IL1RL1 MERTK SDK1	7.82e-08	190	128	11	PF07679
Domain	Ig-like_fold	EPHB4 FCRL2 NTRK2 NTRK3 OBSCN HLA-H CNTN6 IFNAR1 IFNGR2 HHLA2 CADM1 PTPRK CD86 SIGLEC6 ASTN2 IL1RL1 MERTK SDK1	1.55e-06	706	128	18	IPR013783
Domain	-	EPHB4 FCRL2 NTRK2 NTRK3 OBSCN CNTN6 IFNAR1 IFNGR2 HHLA2 CADM1 PTPRK CD86 SIGLEC6 ASTN2 IL1RL1 MERTK SDK1	2.88e-06	663	128	17	2.60.40.10
Domain	FN3	EPHB4 OBSCN CNTN6 IFNAR1 IFNGR2 PTPRK ASTN2 MERTK SDK1	5.23e-06	185	128	9	SM00060
Domain	IG	FCRL2 NTRK2 NTRK3 OBSCN CNTN6 HHLA2 CADM1 PTPRK CD86 SIGLEC6 IL1RL1 MERTK SDK1	6.53e-06	421	128	13	SM00409
Domain	Ig_sub	FCRL2 NTRK2 NTRK3 OBSCN CNTN6 HHLA2 CADM1 PTPRK CD86 SIGLEC6 IL1RL1 MERTK SDK1	6.53e-06	421	128	13	IPR003599
Domain	IG_LIKE	FCRL2 NTRK2 NTRK3 OBSCN HLA-H CNTN6 HHLA2 CADM1 PTPRK CD86 SIGLEC6 IL1RL1 MERTK SDK1	7.04e-06	491	128	14	PS50835
Domain	Ig-like_dom	FCRL2 NTRK2 NTRK3 OBSCN HLA-H CNTN6 HHLA2 CADM1 PTPRK CD86 SIGLEC6 IL1RL1 MERTK SDK1	9.25e-06	503	128	14	IPR007110
Domain	FN3	EPHB4 OBSCN CNTN6 IFNAR1 IFNGR2 PTPRK ASTN2 MERTK SDK1	9.44e-06	199	128	9	PS50853
Domain	FN3_dom	EPHB4 OBSCN CNTN6 IFNAR1 IFNGR2 PTPRK ASTN2 MERTK SDK1	1.40e-05	209	128	9	IPR003961
Domain	Carboxylesterase_B_CS	CEL NLGN1 NLGN2	8.55e-05	13	128	3	IPR019819
Domain	CARBOXYLESTERASE_B_2	CEL NLGN1 NLGN2	1.08e-04	14	128	3	PS00941
Domain	COesterase	CEL NLGN1 NLGN2	1.08e-04	14	128	3	PF00135
Domain	CarbesteraseB	CEL NLGN1 NLGN2	1.08e-04	14	128	3	IPR002018
Domain	fn3	EPHB4 OBSCN CNTN6 IFNGR2 PTPRK MERTK SDK1	1.27e-04	162	128	7	PF00041
Domain	Rhs_assc_core	TENM2 TENM3	1.39e-04	3	128	2	IPR022385
Domain	TPKR_C2	NTRK2 NTRK3	1.39e-04	3	128	2	PF16920
Domain	Tyr_kinase_NGF_rcpt	NTRK2 NTRK3	1.39e-04	3	128	2	IPR020777
Domain	NTRK_C2	NTRK2 NTRK3	1.39e-04	3	128	2	IPR031635
Domain	von_Ebner_gland	OBP2B OBP2A	1.39e-04	3	128	2	IPR002450
Domain	LIPOCALIN	OBP2B OBP2A LCN15	1.99e-04	17	128	3	PS00213
Domain	IGc2	FCRL2 NTRK2 OBSCN CNTN6 CADM1 SIGLEC6 IL1RL1 SDK1	2.18e-04	235	128	8	SM00408
Domain	Ig_sub2	FCRL2 NTRK2 OBSCN CNTN6 CADM1 SIGLEC6 IL1RL1 SDK1	2.18e-04	235	128	8	IPR003598
Domain	Lipocalin	OBP2B OBP2A LCN15	2.38e-04	18	128	3	IPR002345
Domain	TPR	TTC39B SH3TC2 DNAAF4 NPHP3 TTC21B FKBP5	2.63e-04	129	128	6	SM00028
Domain	Tox-GHH_dom	TENM2 TENM3	2.77e-04	4	128	2	IPR028916
Domain	Junctophilin	JPH2 JPH1	2.77e-04	4	128	2	IPR017191
Domain	Tox-GHH	TENM2 TENM3	2.77e-04	4	128	2	PF15636
Domain	Ten_N	TENM2 TENM3	2.77e-04	4	128	2	IPR009471
Domain	Ten_N	TENM2 TENM3	2.77e-04	4	128	2	PF06484
Domain	TENEURIN_N	TENM2 TENM3	2.77e-04	4	128	2	PS51361
Domain	TPR_repeat	TTC39B SH3TC2 DNAAF4 NPHP3 TTC21B FKBP5	3.10e-04	133	128	6	IPR019734
Domain	Tyr_kinase_cat_dom	EPHB4 NTRK2 NTRK3 MAP3K9 MERTK	3.48e-04	88	128	5	IPR020635
Domain	TyrKc	EPHB4 NTRK2 NTRK3 MAP3K9 MERTK	3.48e-04	88	128	5	SM00219
Domain	YD	TENM2 TENM3	4.60e-04	5	128	2	IPR006530
Domain	Nlgn	NLGN1 NLGN2	4.60e-04	5	128	2	IPR000460
Domain	PROTEIN_KINASE_TYR	EPHB4 NTRK2 NTRK3 OBSCN MERTK	5.44e-04	97	128	5	PS00109
Domain	Tyr_kinase_AS	EPHB4 NTRK2 NTRK3 OBSCN MERTK	5.44e-04	97	128	5	IPR008266
Domain	TPR_REGION	TTC39B SH3TC2 DNAAF4 NPHP3 TTC21B FKBP5	9.69e-04	165	128	6	PS50293
Domain	TPR	TTC39B SH3TC2 DNAAF4 NPHP3 TTC21B FKBP5	9.69e-04	165	128	6	PS50005
Domain	TPR-like_helical_dom	TTC39B SH3TC2 SAMD9 DNAAF4 NPHP3 TTC21B FKBP5	1.13e-03	233	128	7	IPR011990
Domain	HP	VILL SVIL	1.27e-03	8	128	2	PS51089
Domain	-	VILL SVIL	1.27e-03	8	128	2	1.10.950.10
Domain	Villin/Gelsolin	VILL SVIL	1.27e-03	8	128	2	IPR007122
Domain	VHP	VILL SVIL	1.27e-03	8	128	2	SM00153
Domain	VHP	VILL SVIL	1.27e-03	8	128	2	PF02209
Domain	Villin_headpiece	VILL SVIL	1.27e-03	8	128	2	IPR003128
Domain	GEL	VILL SVIL	1.27e-03	8	128	2	SM00262
Domain	Lipocln_cytosolic_FA-bd_dom	OBP2B OBP2A LCN15	1.61e-03	34	128	3	IPR000566
Domain	Lipocalin	OBP2B OBP2A LCN15	1.61e-03	34	128	3	PF00061
Domain	Ptc/Disp	NPC1L1 DISP3	1.63e-03	9	128	2	IPR003392
Domain	Patched	NPC1L1 DISP3	1.63e-03	9	128	2	PF02460
Domain	-	OBP2B OBP2A LCN15	1.75e-03	35	128	3	2.40.128.20
Domain	ig	FCRL2 NTRK3 OBSCN PTPRK SIGLEC6 MERTK	1.99e-03	190	128	6	PF00047
Domain	Immunoglobulin	FCRL2 NTRK3 OBSCN PTPRK SIGLEC6 MERTK	1.99e-03	190	128	6	IPR013151
Domain	Interfer-bind	IFNAR1 IFNGR2	2.02e-03	10	128	2	PF09294
Domain	Interferon/interleukin_rcp_dom	IFNAR1 IFNGR2	2.02e-03	10	128	2	IPR015373
Domain	Calycin-like	OBP2B OBP2A LCN15	2.06e-03	37	128	3	IPR011038
Domain	Calycin	OBP2B OBP2A LCN15	2.06e-03	37	128	3	IPR012674
Domain	-	TENM2 EGF TENM3	2.40e-03	39	128	3	2.120.10.30
Domain	Tyr_kinase_rcpt_2_CS	NTRK2 NTRK3	2.46e-03	11	128	2	IPR002011
Domain	Ig_V-set	FCRL2 OBSCN HHLA2 CADM1 CD86 SIGLEC6	2.51e-03	199	128	6	IPR013106
Domain	Ser-Thr/Tyr_kinase_cat_dom	EPHB4 NTRK2 NTRK3 MAP3K9 MERTK	2.62e-03	138	128	5	IPR001245
Domain	RECEPTOR_TYR_KIN_II	NTRK2 NTRK3	2.94e-03	12	128	2	PS00239
Domain	Tissue_fac	IFNAR1 IFNGR2	2.94e-03	12	128	2	PF01108
Domain	Tissue_factor	IFNAR1 IFNGR2	2.94e-03	12	128	2	IPR001187
Domain	-	TTC39B SH3TC2 DNAAF4 NPHP3 TTC21B FKBP5	3.05e-03	207	128	6	1.25.40.10
Domain	TPR_1	SH3TC2 DNAAF4 NPHP3 FKBP5	3.41e-03	90	128	4	IPR001440
Domain	TPR_1	SH3TC2 DNAAF4 NPHP3 FKBP5	3.41e-03	90	128	4	PF00515
Domain	SSD	NPC1L1 DISP3	3.46e-03	13	128	2	IPR000731
Domain	SSD	NPC1L1 DISP3	3.46e-03	13	128	2	PS50156
Domain	NHL	TENM2 TENM3	3.46e-03	13	128	2	PS51125
Domain	TPR-contain_dom	SH3TC2 DNAAF4 NPHP3 TTC21B FKBP5	3.75e-03	150	128	5	IPR013026
Domain	6-blade_b-propeller_TolB-like	TENM2 EGF TENM3	3.85e-03	46	128	3	IPR011042
Domain	Gelsolin	VILL SVIL	4.02e-03	14	128	2	PF00626
Domain	Gelsolin-like_dom	VILL SVIL	4.02e-03	14	128	2	IPR007123
Domain	MORN	JPH2 JPH1	4.02e-03	14	128	2	SM00698
Domain	MORN	JPH2 JPH1	4.62e-03	15	128	2	IPR003409
Domain	MORN	JPH2 JPH1	4.62e-03	15	128	2	PF02493
Domain	TPR_8	TTC39B TTC21B FKBP5	5.74e-03	53	128	3	PF13181
Domain	CarboxyPept-like_regulatory	TENM2 TENM3	5.93e-03	17	128	2	IPR008969
Pubmed	A dual-strategy expression screen for candidate connectivity labels in the developing thalamus.	NTRK2 NTRK3 TENM2 CNTN6 CADM1 TENM3 ASTN2 SDK1	1.89e-09	91	129	8	28558017
Pubmed	Synaptic Adhesion Molecules Regulate the Integration of New Granule Neurons in the Postnatal Mouse Hippocampus and their Impact on Spatial Memory.	NLGN1 CADM1 NLGN2	4.99e-08	3	129	3	27473321
Pubmed	Mutation analysis of 18 nephronophthisis associated ciliopathy disease genes using a DNA pooling and next generation sequencing strategy.	TMEM67 CEP290 NPHP3 TTC21B	5.31e-07	18	129	4	21068128
Pubmed	Nephronophthisis-Related Ciliopathies	TMEM67 CEP290 NPHP3 TTC21B	1.03e-06	21	129	4	27336129
Pubmed	Congenital Hepatic Fibrosis Overview ─ RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY	TMEM67 CEP290 NPHP3 PKD2 TTC21B	1.47e-06	52	129	5	20301743
Pubmed	DSCAM Deficiency Leads to Premature Spine Maturation and Autism-like Behaviors.	NLGN1 CNTN6 CADM1 NLGN2	2.53e-06	26	129	4	34848499
Pubmed	Meta-analysis identifies six new susceptibility loci for atrial fibrillation.	HCN4 PMVK KCNN3	1.07e-05	12	129	3	22544366
Pubmed	Functional proteomics mapping of a human signaling pathway.	SUMF2 DOCK8 PPP1R3B CADM1 KLF10 TENM3 UBE3A ABTB1 MERTK FHL2 SDK1	1.36e-05	591	129	11	15231748
Pubmed	Chondroitin sulfate proteoglycans down-regulate spine formation in cortical neurons by targeting tropomyosin-related kinase B (TrkB) protein.	NTRK2 PTPA	1.37e-05	2	129	2	22389491
Pubmed	Abnormal development of pacinian corpuscles in double trkB;trkC knockout mice.	NTRK2 NTRK3	1.37e-05	2	129	2	17101216
Pubmed	Mapping of the tyrosine kinase receptors trkA (NTRK1), trkB (NTRK2) and trkC(NTRK3) to human chromosomes 1q22, 9q22 and 15q25 by fluorescence in situ hybridization.	NTRK2 NTRK3	1.37e-05	2	129	2	9195161
Pubmed	The TrkB-positive dopaminergic neurons are less sensitive to MPTP insult in the substantia nigra of adult C57/BL mice.	NTRK2 NTRK3	1.37e-05	2	129	2	21562748
Pubmed	MicroRNA-29s suppressed both soluble ST2 release and IFNAR1 expression in human bronchial epithelial cells.	IFNAR1 IL1RL1	1.37e-05	2	129	2	33583067
Pubmed	TRPC4 knockdown suppresses epidermal growth factor-induced store-operated channel activation and growth in human corneal epithelial cells.	TRPC4 EGF	1.37e-05	2	129	2	16033767
Pubmed	ER reorganization is remarkably induced in COS-7 cells accumulating transmembrane protein receptors not competent for export from the endoplasmic reticulum.	CHRNA4 FZD4	1.37e-05	2	129	2	25086772
Pubmed	Deficiency of triad formation in developing skeletal muscle cells lacking junctophilin type 1.	JPH2 JPH1	1.37e-05	2	129	2	12135771
Pubmed	A novel human odorant-binding protein gene family resulting from genomic duplicons at 9q34: differential expression in the oral and genital spheres.	OBP2B OBP2A	1.37e-05	2	129	2	10607840
Pubmed	A versatile single-plasmid system for tissue-specific and inducible control of gene expression in transgenic mice.	JPH2 JPH1	1.37e-05	2	129	2	21518849
Pubmed	TrkB but not trkC receptors are necessary for postnatal maintenance of hippocampal spines.	NTRK2 NTRK3	1.37e-05	2	129	2	17442456
Pubmed	Deficiency of triad junction and contraction in mutant skeletal muscle lacking junctophilin type 1.	JPH2 JPH1	1.37e-05	2	129	2	11535622
Pubmed	Selective activation and down-regulation of Trk receptors by neurotrophins in human neurons co-expressing TrkB and TrkC.	NTRK2 NTRK3	1.37e-05	2	129	2	35536742
Pubmed	Haploinsufficiency in trkB and/or trkC neurotrophin receptors causes structural alterations in the aged hippocampus and amygdala.	NTRK2 NTRK3	1.37e-05	2	129	2	14622193
Pubmed	Neuroligin-2 deletion selectively decreases inhibitory synaptic transmission originating from fast-spiking but not from somatostatin-positive interneurons.	NLGN1 NLGN2	1.37e-05	2	129	2	19889999
Pubmed	A novel nonsense mutation in CEP290 induces exon skipping and leads to a relatively mild retinal phenotype.	CEP290 MERTK	1.37e-05	2	129	2	20130272
Pubmed	Severe sensory deficits but normal CNS development in newborn mice lacking TrkB and TrkC tyrosine protein kinase receptors.	NTRK2 NTRK3	1.37e-05	2	129	2	9421165
Pubmed	Neuroligin expressed in nonneuronal cells triggers presynaptic development in contacting axons.	NLGN1 NLGN2	1.37e-05	2	129	2	10892652
Pubmed	The combined effects of trkB and trkC mutations on the innervation of the inner ear.	NTRK2 NTRK3	1.37e-05	2	129	2	9881298
Pubmed	Discovery and characterization of targetable NTRK point mutations in hematologic neoplasms.	NTRK2 NTRK3	1.37e-05	2	129	2	32315394
Pubmed	UBE3A-mediated PTPA ubiquitination and degradation regulate PP2A activity and dendritic spine morphology.	PTPA UBE3A	1.37e-05	2	129	2	31160454
Pubmed	Evidence of an odorant-binding protein in the human olfactory mucus: location, structural characterization, and odorant-binding properties.	OBP2B OBP2A	1.37e-05	2	129	2	12044155
Pubmed	Lack of TrkB and TrkC signaling alters the synaptogenesis and maturation of mossy fiber terminals in the hippocampus.	NTRK2 NTRK3	1.37e-05	2	129	2	15726425
Pubmed	Hypothalamic-pituitary-adrenal system, neurotrophic factors and clozapine response: association with FKBP5 and NTRK2 genes.	NTRK2 FKBP5	1.37e-05	2	129	2	25751398
Pubmed	High Dimensional Single-Cell Analysis Reveals iNKT Cell Developmental Trajectories and Effector Fate Decision.	IFNAR1 FHL2	1.37e-05	2	129	2	32905761
Pubmed	NLGN1 and NLGN2 in the prefrontal cortex: their role in memory consolidation and strengthening.	NLGN1 NLGN2	1.37e-05	2	129	2	29278843
Pubmed	Tropomyosin receptor kinases B and C are tumor progressive and metastatic marker in colorectal carcinoma.	NTRK2 NTRK3	1.37e-05	2	129	2	23332094
Pubmed	Conditional deletion of TrkC does not modify limbic epileptogenesis.	NTRK2 NTRK3	1.37e-05	2	129	2	22980123
Pubmed	Phosphatidylinositol 4,5-bisphosphate activates Slo3 currents and its hydrolysis underlies the epidermal growth factor-induced current inhibition.	KCNU1 EGF	1.37e-05	2	129	2	20392696
Pubmed	Distinct requirements for TrkB and TrkC signaling in target innervation by sensory neurons.	NTRK2 NTRK3	1.37e-05	2	129	2	11877382
Pubmed	Frequent mutations in the neurotrophic tyrosine receptor kinase gene family in large cell neuroendocrine carcinoma of the lung.	NTRK2 NTRK3	1.37e-05	2	129	2	18293376
Pubmed	A digenic human immunodeficiency characterized by IFNAR1 and IFNGR2 mutations.	IFNAR1 IFNGR2	1.37e-05	2	129	2	29106381
Pubmed	Developing inner ear sensory neurons require TrkB and TrkC receptors for innervation of their peripheral targets.	NTRK2 NTRK3	1.37e-05	2	129	2	7588071
Pubmed	Junctophilin damage contributes to early strength deficits and EC coupling failure after eccentric contractions.	JPH2 JPH1	1.37e-05	2	129	2	19940065
Pubmed	USP15 promotes the apoptosis of degenerative nucleus pulposus cells by suppressing the PI3K/AKT signalling pathway.	USP15 FKBP5	1.37e-05	2	129	2	33135363
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SIN3B SH3TC2 CEP290 NPHP3 TTC21B DISP3 DIP2C ASTN2 NLGN2 HECTD1	1.63e-05	493	129	10	15368895
Pubmed	Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.	NTRK2 NTRK3 NLGN1 CNTN6 EGF UBE3A ASTN2 NLGN2	1.73e-05	300	129	8	19086053
Pubmed	Developmental waves of mechanosensitivity acquisition in sensory neuron subtypes during embryonic development.	NTRK2 NTRK3 TRPC4 PKD2	2.19e-05	44	129	4	19322198
Pubmed	Global genetic analysis in mice unveils central role for cilia in congenital heart disease.	EPHB4 TMEM67 DNAAF4 CEP290 HECTD1	3.69e-05	100	129	5	25807483
Pubmed	Developmental expression and subcellular distribution of synaptotagmin 11 in rat hippocampus.	NLGN1 NLGN2	4.09e-05	3	129	2	22960622
Pubmed	Possible pheromone-carrier function of two lipocalin proteins in the vomeronasal organ.	OBP2B OBP2A	4.09e-05	3	129	2	7813422
Pubmed	EGF-mediated migration signaling activated by N-acetylglucosaminyltransferase-V via receptor protein tyrosine phosphatase kappa.	EGF PTPRK	4.09e-05	3	129	2	19236842
Pubmed	Survival of inner ear sensory neurons in trk mutant mice.	NTRK2 NTRK3	4.09e-05	3	129	2	9232598
Pubmed	Unique versus Redundant Functions of Neuroligin Genes in Shaping Excitatory and Inhibitory Synapse Properties.	NLGN1 NLGN2	4.09e-05	3	129	2	28607166
Pubmed	Gangliosides activate Trk receptors by inducing the release of neurotrophins.	NTRK2 NTRK3	4.09e-05	3	129	2	12388556
Pubmed	Ca2+-dependent proteolysis of junctophilin-1 and junctophilin-2 in skeletal and cardiac muscle.	JPH2 JPH1	4.09e-05	3	129	2	23148318
Pubmed	Physical interaction of junctophilin and the CaV1.1 C terminus is crucial for skeletal muscle contraction.	JPH2 JPH1	4.09e-05	3	129	2	29632175
Pubmed	The Effects of IGF-1 on Trk Expressing DRG Neurons with HIV-gp120- Induced Neurotoxicity.	NTRK2 NTRK3	4.09e-05	3	129	2	26652865
Pubmed	Zika Virus Infection in Mice Causes Panuveitis with Shedding of Virus in Tears.	IFNAR1 MERTK	4.09e-05	3	129	2	27612415
Pubmed	The development of myelinated nociceptors is dependent upon trks in the trigeminal ganglion.	NTRK2 NTRK3	4.09e-05	3	129	2	15530548
Pubmed	Dok5 is substrate of TrkB and TrkC receptors and involved in neurotrophin induced MAPK activation.	NTRK2 NTRK3	4.09e-05	3	129	2	16647839
Pubmed	TrkB and TrkC agonist antibodies improve function, electrophysiologic and pathologic features in Trembler J mice.	NTRK2 NTRK3	4.09e-05	3	129	2	20553714
Pubmed	Developmental dependency of Merkel endings on trks in the palate.	NTRK2 NTRK3	4.09e-05	3	129	2	11295244
Pubmed	Dysregulated TRK signalling is a therapeutic target in CYLD defective tumours.	NTRK2 NTRK3	4.09e-05	3	129	2	21552290
Pubmed	TrkB and TrkC neurotrophin receptors cooperate in promoting survival of hippocampal and cerebellar granule neurons.	NTRK2 NTRK3	4.09e-05	3	129	2	8918886
Pubmed	Trk receptor expression and inhibition in neuroblastomas.	NTRK2 NTRK3	4.09e-05	3	129	2	19417027
Pubmed	Synaptic Neurexin Complexes: A Molecular Code for the Logic of Neural Circuits.	NLGN1 NLGN2	4.09e-05	3	129	2	29100073
Pubmed	Adipose-derived lipocalin 14 alleviates hyperglycaemia by suppressing both adipocyte glycerol efflux and hepatic gluconeogenesis in mice.	OBP2B OBP2A	4.09e-05	3	129	2	26592241
Pubmed	Prognostic value of tropomyosin-related kinases A, B, and C in gastric cancer.	NTRK2 NTRK3	4.09e-05	3	129	2	26459250
Pubmed	The Trk tyrosine kinase inhibitor K252a regulates growth of lung adenocarcinomas.	NTRK2 NTRK3	4.09e-05	3	129	2	16862449
Pubmed	NeuroD regulates neuronal migration.	NTRK2 NTRK3	4.09e-05	3	129	2	23652629
Pubmed	Human trks: molecular cloning, tissue distribution, and expression of extracellular domain immunoadhesins.	NTRK2 NTRK3	4.09e-05	3	129	2	7823156
Pubmed	Neuroligins Sculpt Cerebellar Purkinje-Cell Circuits by Differential Control of Distinct Classes of Synapses.	NLGN1 NLGN2	4.09e-05	3	129	2	26291161
Pubmed	ESMO recommendations on the standard methods to detect NTRK fusions in daily practice and clinical research.	NTRK2 NTRK3	4.09e-05	3	129	2	31268127
Pubmed	Neuroligin-3 is a neuronal adhesion protein at GABAergic and glutamatergic synapses.	NLGN1 NLGN2	4.09e-05	3	129	2	17897391
Pubmed	RIZ2 at the crossroad of the EGF/EGFR signaling in colorectal cancer.	PRDM2 EGF	4.09e-05	3	129	2	37853459
Pubmed	Neuroligins determine synapse maturation and function.	NLGN1 NLGN2	4.09e-05	3	129	2	16982420
Pubmed	NTRK fusion analysis reveals enrichment in Middle Eastern BRAF wild-type PTC.	NTRK2 NTRK3	4.09e-05	3	129	2	33524004
Pubmed	Transcriptional programming mediated by the histone demethylase KDM5C regulates dendritic cell population heterogeneity and function.	KDM5C IFNAR1	4.09e-05	3	129	2	39052479
Pubmed	Characterization of human junctophilin subtype genes.	JPH2 JPH1	4.09e-05	3	129	2	10891348
Pubmed	Junctophilins: a novel family of junctional membrane complex proteins.	JPH2 JPH1	4.09e-05	3	129	2	10949023
Pubmed	Dimerization of the Trk receptors in the plasma membrane: effects of their cognate ligands.	NTRK2 NTRK3	4.09e-05	3	129	2	30366959
Pubmed	Distinct roles of neuroligin-1 and SynCAM1 in synapse formation and function in primary hippocampal neuronal cultures.	NLGN1 CADM1	4.09e-05	3	129	2	22542674
Pubmed	TRK Fusions Are Enriched in Cancers with Uncommon Histologies and the Absence of Canonical Driver Mutations.	NTRK2 NTRK3	4.09e-05	3	129	2	31871300
Pubmed	Prospective Evaluation of Kidney Disease in Joubert Syndrome.	TMEM67 CEP290	4.09e-05	3	129	2	29146704
Pubmed	Developmental dependency of Meissner corpuscles on trkB but not trkA or trkC.	NTRK2 NTRK3	4.09e-05	3	129	2	10674466
Pubmed	Conditional ablation of neuroligin-1 in CA1 pyramidal neurons blocks LTP by a cell-autonomous NMDA receptor-independent mechanism.	NLGN1 NLGN2	4.09e-05	3	129	2	27217145
Pubmed	Expression of mRNAs for neurotrophic factors (NGF, BDNF, NT-3, and GDNF) and their receptors (p75NGFR, trkA, trkB, and trkC) in the adult human peripheral nervous system and nonneural tissues.	NTRK2 NTRK3	4.09e-05	3	129	2	8895847
Pubmed	Gene expression of TRK neurotrophin receptors in advanced neuroblastomas in Singapore--a pilot study.	NTRK2 NTRK3	4.09e-05	3	129	2	21728718
Pubmed	Neurotrophin actions during the development of the peripheral nervous system.	NTRK2 NTRK3	4.09e-05	3	129	2	10383116
Pubmed	Junctophilin 1 and 2 proteins interact with the L-type Ca2+ channel dihydropyridine receptors (DHPRs) in skeletal muscle.	JPH2 JPH1	4.09e-05	3	129	2	22020936
Pubmed	Pan-Trk Immunohistochemistry Is an Efficient and Reliable Screen for the Detection of NTRK Fusions.	NTRK2 NTRK3	4.09e-05	3	129	2	28719467
Pubmed	DNA methylation-dependent regulation of TrkA, TrkB, and TrkC genes in human hepatocellular carcinoma.	NTRK2 NTRK3	4.09e-05	3	129	2	21295543
Pubmed	The alarmin interleukin-33 promotes the expansion and preserves the stemness of Tcf-1+ CD8+ T cells in chronic viral infection.	IFNAR1 IL1RL1	4.09e-05	3	129	2	36809763
Pubmed	Hypomorphic mutations in syndromic encephalocele genes are associated with Bardet-Biedl syndrome.	TMEM67 CEP290	4.09e-05	3	129	2	18327255
Pubmed	A chemical-genetic approach to studying neurotrophin signaling.	NTRK2 NTRK3	4.09e-05	3	129	2	15820690
Pubmed	Junctophilins 1, 2, and 3 all support voltage-induced Ca2+ release despite considerable divergence.	JPH2 JPH1	4.09e-05	3	129	2	35089322
Pubmed	Highly increased maspin expression corresponds with up-regulation of miR-21 in endometrial cancer: a preliminary report.	PDCD4 SERPINB5	4.09e-05	3	129	2	21330826
Pubmed	Crystal Structures of Neurotrophin Receptors Kinase Domain.	NTRK2 NTRK3	4.09e-05	3	129	2	28215291
Pubmed	Differential effects of combined trk receptor mutations on dorsal root ganglion and inner ear sensory neurons.	NTRK2 NTRK3	4.09e-05	3	129	2	8575307
Pubmed	Activity-dependent validation of excitatory versus inhibitory synapses by neuroligin-1 versus neuroligin-2.	NLGN1 NLGN2	4.09e-05	3	129	2	17582332
Pubmed	The trk family of tyrosine protein kinase receptors.	NTRK2 NTRK3	4.09e-05	3	129	2	1751544
Cytoband	Xp11.22-p11.21	TRO KDM5C	4.68e-05	4	129	2	Xp11.22-p11.21
Cytoband	Ensembl 112 genes in cytogenetic band chr9q34	CEL OBP2B OBP2A PTPA LCN15 FIBCD1	3.30e-04	325	129	6	chr9q34
Cytoband	9q34	OBP2B OBP2A PTPA	4.84e-04	54	129	3	9q34
Cytoband	7q21.2	SAMD9 PEX1	8.03e-04	15	129	2	7q21.2
GeneFamily	Fibronectin type III domain containing	EPHB4 OBSCN CNTN6 IFNGR2 PTPRK ASTN2 MERTK SDK1	1.32e-06	160	90	8	555
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	NTRK2 NTRK3 OBSCN CNTN6 SIGLEC6 IL1RL1 MERTK SDK1	1.39e-06	161	90	8	593
GeneFamily	Tetratricopeptide repeat domain containing\|Bardet-Biedl syndrome associated\|BBSome	TTC39B SH3TC2 DNAAF4 NPHP3 TTC21B FKBP5	2.34e-05	115	90	6	769
GeneFamily	Immunoglobulin like domain containing	FCRL2 CADM1 PTPRK CD86 IL1RL1 MERTK SDK1	5.01e-05	193	90	7	594
GeneFamily	Lipocalins	OBP2B OBP2A LCN15	1.09e-04	19	90	3	631
GeneFamily	Interferon receptors	IFNAR1 IFNGR2	2.43e-04	5	90	2	599
GeneFamily	Potassium calcium-activated channels	KCNU1 KCNN3	3.63e-04	6	90	2	255
GeneFamily	Gelsolin/villins	VILL SVIL	6.73e-04	8	90	2	950
GeneFamily	Receptor Tyrosine Kinases\|CD molecules	NTRK2 NTRK3 MERTK	1.03e-03	40	90	3	321
GeneFamily	Cyclophilin peptidylprolyl isomerases	PPWD1 PTPA	3.97e-03	19	90	2	909
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HGABA	NTRK3 STK32B ENC1 PEX1 GRID1 NLGN1 REV3L TENM2 CHRNA4 PRDM2 JPH1 CADM1 PTPRK CADPS MAP3K9 KCNN3 HYDIN PDE11A	7.38e-06	1106	128	18	M39071
ToppCell	COVID-19-Heart-CM_1\|Heart / Disease (COVID-19 only), tissue and cell type	NRAP OBSCN JPH2 NLGN1 LMOD2 TENM2 CADM1 CADPS SVIL FHL2	2.92e-10	195	129	10	f1ef50331eda8f1239dba6ea970df4eaccf032f1
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	NRAP OBSCN NLGN1 LMOD2 TENM2 JPH1 SVIL DIP2C FHL2	4.47e-09	189	129	9	0a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCell	COVID-19-Heart-CM_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	NRAP OBSCN JPH2 LMOD2 TENM2 CADPS SVIL FHL2	7.00e-08	185	129	8	549eeb521c3985bff396ea0f202db21822efa51f
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|RV / Chamber and Cluster_Paper	NRAP OBSCN LMOD2 TENM2 JPH1 SVIL DIP2C FHL2	8.60e-08	190	129	8	93c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCell	COVID-19-Heart-CM_+_EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	NRAP OBSCN JPH2 LMOD2 TENM2 CADM1 SVIL FHL2	9.70e-08	193	129	8	dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCell	RA-03._Atrial_Cardiomyocyte\|RA / Chamber and Cluster_Paper	NRAP OBSCN JPH2 TENM2 CADPS SVIL ASTN2 FHL2	1.01e-07	194	129	8	c3535f7cc0076653c72db582047cff053c322397
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL3A1 MATN2 NTRK3 TRPC4 JPH2 CADPS SVIL FHL2	1.09e-07	196	129	8	1522958a92e0126326a9f0d9fb1c5b5c50b001ea
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL3A1 MATN2 NTRK3 TRPC4 JPH2 CADPS SVIL FHL2	1.09e-07	196	129	8	1c8294014713684b50885e638668f2ce75f357f0
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TMEM67 DNAH3 DNAAF4 CEP290 HHLA2 KCNN3 VWA3B HYDIN	1.14e-07	197	129	8	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	COVID-19-Heart-CM_3\|COVID-19 / Disease (COVID-19 only), tissue and cell type	NRAP OBSCN JPH2 LMOD2 TENM2 JPH1 FHL2	8.32e-07	176	129	7	9df7a124ebafb0087da0cda133a394275d7bed81
ToppCell	COVID-19-Heart-CM_3\|Heart / Disease (COVID-19 only), tissue and cell type	NRAP OBSCN LMOD2 TENM2 JPH1 CADM1 SVIL	1.04e-06	182	129	7	287fcc3897ae08841f6f85ae6c9cef16f75b1dd1
ToppCell	COVID-19-Heart-CM_4\|COVID-19 / Disease (COVID-19 only), tissue and cell type	NRAP LMOD2 TENM2 JPH1 EGF CADPS FHL2	1.08e-06	183	129	7	2902b6e8aa9a6f62bc1a792c971ab7f651a8e676
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|LV / Chamber and Cluster_Paper	NRAP OBSCN NLGN1 LMOD2 TENM2 SVIL FHL2	1.12e-06	184	129	7	ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCell	COVID-19-Heart-CM_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	NRAP OBSCN JPH2 LMOD2 TENM2 CADPS FHL2	1.12e-06	184	129	7	e737f0f14c49b07bbb04a165083ac32210bc5690
ToppCell	NS-moderate-d_16-33-Epithelial-Ciliated\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TMEM67 DNAH3 NWD1 HHLA2 VWA3B HYDIN FBXO15	1.16e-06	185	129	7	5e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	NRAP OBSCN NLGN1 LMOD2 TENM2 CADM1 FHL2	1.16e-06	185	129	7	6baccb26f999145e51b91d94315bf8d4655bef31
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NTRK2 STK32B CADM1 EGF KCNN3 ASTN2 FKBP5	1.20e-06	186	129	7	1850583d23903d08226aeb0edb3e07b0994330e4
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NTRK2 STK32B CADM1 EGF KCNN3 ASTN2 FKBP5	1.20e-06	186	129	7	4dafc215c42e7949f932a3627359c107943b5d6b
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DENND4A PPP1R3B NLGN1 DIP2C ASTN2 FHL2 HYDIN	1.20e-06	186	129	7	f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DENND4A PPP1R3B NLGN1 DIP2C ASTN2 FHL2 HYDIN	1.25e-06	187	129	7	c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL3A1 MATN2 NTRK3 TRPC4 GRID1 TENM3 FHL2	1.65e-06	195	129	7	edd4cd8402af81737b2074f9dce71cc6ab09be7e
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GRID1 HHLA2 EGF ASTN2 NLGN2 SDK1	1.75e-06	125	129	6	b162a5bfbb8ac5e65e13578fef9de442a9e4fd8b
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_ciliated\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DNAH3 NWD1 HHLA2 TEX26 VWA3B HYDIN FBXO15	1.89e-06	199	129	7	2498237b9e895ca4826a3378d9d40989968df72b
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_ciliated-Ciliated\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DNAH3 NWD1 HHLA2 TEX26 VWA3B HYDIN FBXO15	1.89e-06	199	129	7	542ec45c931b40738df1f3777b00c83be33a514a
ToppCell	LPS_IL1RA-Epithelial_airway-airway_epithelial-Ciliated\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	DNAH3 NWD1 HCN4 DNAAF4 TEX26 VWA3B HYDIN	1.95e-06	200	129	7	4992dbf0514d674017315dbd20d91dfec0c608e9
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NWD1 TRPC4 EGF TENM3 CLEC4G IL1RL1	5.86e-06	154	129	6	5ed64bbf603290e6dc34f81d145982690b89dd0d
ToppCell	critical-Myeloid-Mast_cell\|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	TRO CADM1 CADPS SIGLEC6 IL1RL1 ATP1A4	8.70e-06	165	129	6	34a1cc6ccd46c059354e8fbde1ac69f202695a4e
ToppCell	PND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	OBSCN NLGN1 AASDH LMOD2 TENM2 FHL2	9.01e-06	166	129	6	390cf5e56b72fcaf3b8520930bd35a3e3e173711
ToppCell	PND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	OBSCN NLGN1 AASDH LMOD2 TENM2 FHL2	9.01e-06	166	129	6	9a341dc7b756252caeaac1e934384911c880a634
ToppCell	NS-critical-d_07-13-Myeloid-Mast_cell\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TRO CADM1 CADPS SIGLEC6 IL1RL1 ATP1A4	9.32e-06	167	129	6	8a14fd980d8ebe8ef0216221f619d31aaa27ff15
ToppCell	COVID-19-Heart-CM_+_Macrophage\|COVID-19 / Disease (COVID-19 only), tissue and cell type	NRAP OBSCN JPH2 LMOD2 TENM2 FHL2	1.03e-05	170	129	6	3f15242a1d3e4e9871d9170b2ef05842fb609c29
ToppCell	COVID-19-Heart-CM_+_Macrophage\|Heart / Disease (COVID-19 only), tissue and cell type	NRAP OBSCN TENM2 CD86 MERTK FHL2	1.03e-05	170	129	6	4232fe937909f93d3736988c707b8f95ce993398
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL3A1 NTRK2 MATN2 NTRK3 FZD4 TENM3	1.30e-05	177	129	6	30f82b04e48940bfcaf2c22677efe6d57ae3f1a7
ToppCell	RV-03._Atrial_Cardiomyocyte\|RV / Chamber and Cluster_Paper	TRPC4 OBSCN GCM1 SVIL FHL2	1.38e-05	105	129	5	49e16b11f16e83a7d17d162c14bce991201bcc2a
ToppCell	COVID-19-Heart-VSMC\|Heart / Disease (COVID-19 only), tissue and cell type	NTRK2 NTRK3 TRPC4 GRID1 SDK1 PACSIN2	1.38e-05	179	129	6	a69ad6912b5c10bb9f9d800f724c792341e9bab1
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL3A1 TMEM67 OBSCN GRID1 SVIL SDK1	1.38e-05	179	129	6	a1ea8daa0fe8900f5a04b555c77fe8ebdaa3908d
ToppCell	Control-Fibroblasts-Airway_smooth_muscle\|Control / group, cell type (main and fine annotations)	COL3A1 NTRK2 NTRK3 JPH2 NLGN1 SVIL	1.43e-05	180	129	6	d0de12749ef0f51f0931c6e7b9b99966bdbc3ec1
ToppCell	COVID-19-Heart-CM_+_EC_+_Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	NRAP OBSCN JPH2 LMOD2 TENM2 FHL2	1.47e-05	181	129	6	719eb532453ab7cd7893726885bc75d74a10b21e
ToppCell	facs-Heart-LA-3m-Mesenchymal-atrial_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRAP OBP2A OBSCN LMOD2 DISP3 FHL2	1.57e-05	183	129	6	905e1e9be0f15be184447df04b134a6aa8279074
ToppCell	facs-Heart-LA-3m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRAP OBP2A OBSCN LMOD2 DISP3 FHL2	1.57e-05	183	129	6	92eed783347a372b850de3189e72525082390014
ToppCell	E18.5-samps-Mesenchymal-Myofibroblast\|E18.5-samps / Age Group, Lineage, Cell class and subclass	TMEM67 ENC1 NLGN1 JPH1 NLGN2 FHL2	1.57e-05	183	129	6	de08f9ea02b7244d5a8788064631d10f06565337
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OBSCN GRID1 DISP3 ATP1A4 SDK1 HYDIN	1.62e-05	184	129	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OBSCN GRID1 DISP3 ATP1A4 SDK1 HYDIN	1.62e-05	184	129	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OBSCN GRID1 DISP3 ATP1A4 SDK1 HYDIN	1.62e-05	184	129	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NTRK2 STK32B CADM1 EGF KCNN3 ASTN2	1.67e-05	185	129	6	03f64a7132b13a01ba47187e0e15c13ac88f7cb2
ToppCell	Fetal_29-31_weeks-Epithelial-ciliated_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DNAH3 NWD1 HHLA2 TEX26 VWA3B FBXO15	1.67e-05	185	129	6	3e39a3cb534dfe2301930f3e2f7e8cefb522c158
ToppCell	NS-moderate-d_07-13-Epithelial-Ciliated\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DNAH3 NWD1 DNAAF4 TEX26 VWA3B HYDIN	1.72e-05	186	129	6	85787ff207f109ec7e3c0f729ba9bda739c2fdc9
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NTRK2 STK32B CADM1 EGF MERTK FKBP5	1.77e-05	187	129	6	b93cf4dfe8ffb89348ee7bccc9f284189f7240a2
ToppCell	tumor_Lung-Epithelial_cells-tS3\|Epithelial_cells / Location, Cell class and cell subclass	TMEM67 NWD1 DNAAF4 KCNN3 VWA3B HYDIN	1.77e-05	187	129	6	3cea677279e71fdb9879530dea10a5e6393beacd
ToppCell	Children_(3_yrs)-Mesenchymal-pericyte_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NTRK3 TRPC4 OBSCN JPH2 GRID1 FKBP5	1.77e-05	187	129	6	86250acf088ec0c4800a0dfa031b0d4f7e52c342
ToppCell	21-Trachea-Epithelial-Intermediate_ciliated\|Trachea / Age, Tissue, Lineage and Cell class	NWD1 HHLA2 TEX26 VWA3B HYDIN FBXO15	1.77e-05	187	129	6	1a2178a195d078d1963947b327c6d0d4f2f48341
ToppCell	LA-13._Vascular_Smooth_Muscle\|LA / Chamber and Cluster_Paper	NTRK3 TRPC4 SVIL PKD2 SDK1 PACSIN2	1.83e-05	188	129	6	34e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PPP1R3B NLGN1 DIP2C ASTN2 FHL2 HYDIN	1.83e-05	188	129	6	af740fa78542438fdff627ea1f74f4eee43316be
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL3A1 DOCK8 NTRK3 TRPC4 JPH2 GRID1	1.88e-05	189	129	6	fac5c291a9a87418bb0878c3d624829bdbf1f428
ToppCell	COVID-19-lung-Ciliated\|lung / Disease (COVID-19 only), tissue and cell type	DNAH3 NWD1 HHLA2 VWA3B HYDIN FBXO15	1.88e-05	189	129	6	27329c4661aebabd19fac7fe5dca263fe99d76f3
ToppCell	COVID-19-Heart\|COVID-19 / Disease (COVID-19 only), tissue and cell type	NRAP OBSCN JPH2 LMOD2 TENM2 FHL2	1.94e-05	190	129	6	918ad5037881212008f9f69d5df5da91fd01422c
ToppCell	Nasal_Brush-Epithelial-Ciliated_2\|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	TMEM67 DNAH3 DNAAF4 TEX26 VWA3B HYDIN	1.94e-05	190	129	6	9ce7df056bfb24d70db4c3c4a2c57d89115de877
ToppCell	Nasal_Brush-Epithelial-Ciliated_2\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	TMEM67 DNAH3 DNAAF4 TEX26 VWA3B HYDIN	1.94e-05	190	129	6	833481ace2800354712e2ce709d5cdfd0aed3d42
ToppCell	COVID-19-Heart-CM_4\|Heart / Disease (COVID-19 only), tissue and cell type	NRAP TENM2 JPH1 CADM1 EGF CADPS	1.94e-05	190	129	6	3729648a17093b438398b82e32bbccc3af7b8c5d
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL3A1 NTRK3 TRPC4 JPH2 GRID1 TENM3	1.94e-05	190	129	6	70c86dd454afb21d4a85db56c5f369d4b342bc97
ToppCell	E15.5-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	COL3A1 NTRK2 MATN2 NTRK3 TENM2 TENM3	2.00e-05	191	129	6	053b3664f509baa107feaf90730f80ebf9ac8f14
ToppCell	LA-03._Atrial_Cardiomyocyte\|LA / Chamber and Cluster_Paper	NRAP OBSCN JPH2 TENM2 CADPS SVIL	2.00e-05	191	129	6	5d1b674eb7703830b7ce8bbeac3363cabd0e6ae9
ToppCell	nucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	TMEM67 DNAH3 NWD1 HHLA2 VWA3B HYDIN	2.00e-05	191	129	6	e417bf491f8b8d7838a61f7f4f6b1740ba97aa3f
ToppCell	nucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	TMEM67 DNAH3 NWD1 HHLA2 VWA3B HYDIN	2.00e-05	191	129	6	9d31c8424d35bdc0c27188b68bfd0f731af3600b
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-MUC16+_ciliated\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	DNAH3 NWD1 HHLA2 TEX26 VWA3B HYDIN	2.00e-05	191	129	6	e81cd65dbf0ef1c2ab7088f73ce605d456dd3a7a
ToppCell	nucseq-Epithelial-Epithelial_Airway\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	TMEM67 DNAH3 NWD1 HHLA2 VWA3B HYDIN	2.00e-05	191	129	6	1c528f72c9ef3ef3a850b05e4a9715190832270c
ToppCell	Bronchial_Biopsy-Epithelial-Ciliated_1\|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X	TMEM67 DNAH3 DNAAF4 VWA3B HYDIN FBXO15	2.06e-05	192	129	6	be592e661367affced9ebe80849b466e6adb3a34
ToppCell	LV-04._Ventricular_Cardiomyocyte_I\|LV / Chamber and Cluster_Paper	NRAP OBSCN NLGN1 TENM2 SVIL FHL2	2.06e-05	192	129	6	ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	NLGN1 PTPRK SVIL DIP2C SDK1 FKBP5	2.06e-05	192	129	6	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	NS-moderate-d_0-4\|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TMEM67 DNAH3 NWD1 VWA3B SDK1 HYDIN	2.12e-05	193	129	6	ea345d34440b25f65358a53dc72831998d1c3620
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-MUC16+_ciliated\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	DNAH3 NWD1 TEX26 VWA3B HYDIN FBXO15	2.18e-05	194	129	6	756082a0f5953b52229bb60d40b84701cb6cb23d
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TMEM67 DNAH3 DNAAF4 HHLA2 TEX26 HYDIN	2.18e-05	194	129	6	3cd90d01ed5a5ce65aad8284dab2537ec16e3d7c
ToppCell	NS-critical-d_07-13-Epithelial-Ciliated\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TMEM67 DNAH3 NWD1 DNAAF4 VWA3B HYDIN	2.18e-05	194	129	6	1ae8a10e508e672e6677f0e3c986ac30d05adeb3
ToppCell	RA-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	NRAP NTRK2 OBSCN CADPS SVIL ASTN2	2.18e-05	194	129	6	89812fb164065041357bb37a3c2d87028ec3de4e
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TMEM67 DNAH3 NWD1 DNAAF4 VWA3B HYDIN	2.24e-05	195	129	6	649fd2336e963f6a150d182a53ad5dd838ca80b1
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL3A1 MATN2 TRPC4 GRID1 TENM3 FHL2	2.24e-05	195	129	6	49c99553629cdd83ee56a2e508d5bc8d34b8507b
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-Ciliated\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	DNAH3 HHLA2 TEX26 VWA3B HYDIN FBXO15	2.24e-05	195	129	6	cfcf554b436083179dea1d6fd6e3a800ea2430fe
ToppCell	COVID-19-Heart-CM_2\|Heart / Disease (COVID-19 only), tissue and cell type	NRAP OBSCN LMOD2 TENM2 SVIL FHL2	2.24e-05	195	129	6	75fc81bddb246dca3b437fb60827b1d4fe416405
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL3A1 MATN2 TRPC4 GRID1 TENM3 FHL2	2.24e-05	195	129	6	dd281a249854800f737dc22e0f375f66dfb5cf5f
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TMEM67 DNAH3 DNAAF4 HHLA2 TEX26 HYDIN	2.24e-05	195	129	6	db4270c135c392ed443670981656e3cd5b95939d
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TMEM67 DNAH3 NWD1 DNAAF4 VWA3B HYDIN	2.24e-05	195	129	6	129ad5f4253ecb1a8477cc38773e6e91ea9570b0
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TMEM67 DNAH3 NWD1 DNAAF4 VWA3B HYDIN	2.24e-05	195	129	6	3e70ee987d66d450062d5df3d7c733ccc7344470
ToppCell	moderate-Epithelial-Ciliated\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	TMEM67 DNAH3 NWD1 DNAAF4 VWA3B HYDIN	2.24e-05	195	129	6	3486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCell	moderate-Epithelial-Ciliated\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	TMEM67 DNAH3 NWD1 DNAAF4 VWA3B HYDIN	2.24e-05	195	129	6	e80f5cdf0b18066b3e6c2f5452e58f101c67932c
ToppCell	COVID-19-kidney-Fibroblast-2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	COL3A1 TRPC4 REV3L TENM3 FHL2 SDK1	2.24e-05	195	129	6	3d62ce1c696f47d4d7eb0c5bb0eec2c24b122bb2
ToppCell	critical-Epithelial-Ciliated\|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	TMEM67 DNAH3 NWD1 DNAAF4 VWA3B HYDIN	2.31e-05	196	129	6	27b855c6e1ae44f16db998cf0e81bd686b9cee7e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL3A1 MATN2 TRPC4 GRID1 TENM3 FHL2	2.31e-05	196	129	6	fa445f4240c521cf04eb2e2f79a5c55fda31209a
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL3A1 MATN2 TRPC4 GRID1 TENM3 FHL2	2.31e-05	196	129	6	802f61e78a9a1030a86c4a980c398a73cd4d1574
ToppCell	5'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NTRK2 MATN2 NTRK3 CNTN6 CADM1 TENM3	2.31e-05	196	129	6	e6adcfe1a00d4910e0b92848f8a80224e0d6db12
ToppCell	wk_08-11-Mesenchymal-Fibroblast-Adventitial_fibro\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	COL3A1 NTRK2 MATN2 NTRK3 FZD4 SVIL	2.31e-05	196	129	6	eed9fe83ffc1f79493b70778962a671dd9f481e0
ToppCell	IPF-Epithelial\|IPF / Disease state, Lineage and Cell class	TMEM67 DNAH3 PTPRK VWA3B SDK1 HYDIN	2.31e-05	196	129	6	87d9881cfec461a5d89b688a83749b618c519485
ToppCell	Tracheal-NucSeq-Epithelial-Epi_submucosal-gland-Myoepithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NTRK2 MATN2 NTRK3 JPH2 FHL2 CYB5R2	2.38e-05	197	129	6	f0475ad9c09c6da418dba17d3d3c1aaa2ef9ab4e
ToppCell	PSB-critical-LOC-Epithelial-Ciliated\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TMEM67 DNAH3 DNAAF4 VWA3B HYDIN FBXO15	2.38e-05	197	129	6	6865f4831eb23794fb88a8649d48d497bbae3f44
ToppCell	NS-moderate-d_0-4-Epithelial-Ciliated\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TMEM67 DNAH3 NWD1 DNAAF4 VWA3B HYDIN	2.38e-05	197	129	6	71fea4aa6ce96c7693fa94792d08770622873850
ToppCell	11.5-Airway-Mesenchymal-Mesenchyme_SERPINF1-high\|Airway / Age, Tissue, Lineage and Cell class	COL3A1 NTRK2 MATN2 NTRK3 TENM3 SVIL	2.38e-05	197	129	6	9a053a32ff9c3a85ef9a3382453acd619cc48546
ToppCell	critical-Epithelial-Ciliated\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	TMEM67 DNAH3 NWD1 DNAAF4 VWA3B HYDIN	2.44e-05	198	129	6	ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL3A1 MATN2 TENM3 PTPRK SVIL KCNN3	2.44e-05	198	129	6	12cd9f0bbad8dce5199ebfed1c4a8080710ca055
ToppCell	LPS_anti-TNF-Epithelial_airway-airway_epithelial-Ciliated\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	DNAH3 NWD1 HCN4 DNAAF4 VWA3B HYDIN	2.51e-05	199	129	6	15f7814b7074170eee7ccacaa670b1d128fc68bb
ToppCell	Bronchial-10x5prime-Stromal-Pericyte-Muscle_pericyte_pulmonary\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	TRPC4 OBSCN JPH2 GRID1 CADM1 FIBCD1	2.59e-05	200	129	6	12326cc6f0af24bacba9493dc79e7c7347db2f41
ToppCell	distal-3-Hematologic-Platelet/Megakaryocyte\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	DNAH3 NWD1 CFAP92 MTTP HYDIN FBXO15	2.59e-05	200	129	6	f5f5a8b0e4d802d95dc42646dd5e7d7daaad72b4
Disease	cystic kidney disease (implicated_via_orthology)	EPHB4 TMEM67 CEP290 TTC21B	6.12e-08	10	124	4	DOID:2975 (implicated_via_orthology)
Disease	Meckel-Gruber syndrome	TMEM67 CEP290 NPHP3	8.51e-06	10	124	3	cv:C0265215
Disease	Autistic Disorder	KDM5C NTRK2 NLGN1 CHRNA4 CADM1 EGF UBE3A ASTN2	1.53e-05	261	124	8	C0004352
Disease	Bardet-Biedl syndrome 14	TMEM67 CEP290	1.75e-05	2	124	2	cv:C2673874
Disease	BARDET-BIEDL SYNDROME 14 (disorder)	TMEM67 CEP290	1.75e-05	2	124	2	C2673874
Disease	BARDET-BIEDL SYNDROME 14	TMEM67 CEP290	1.75e-05	2	124	2	615991
Disease	Bardet-Biedl syndrome 14 (is_implicated_in)	TMEM67 CEP290	1.75e-05	2	124	2	DOID:0110136 (is_implicated_in)
Disease	Nephronophthisis	TMEM67 NPHP3 TTC21B	2.01e-05	13	124	3	C0687120
Disease	smoking status measurement	SAMD9 NRAP TRPC4 STK32B GRID1 NLGN1 REV3L TENM2 CHRNA4 HHLA2 PTPRK XRN1 FHL2 USP15 SDK1 PDE11A	2.96e-05	1160	124	16	EFO_0006527
Disease	Disorder of eye	TMEM67 CEP290 FZD4 NPHP3 TTC21B MTTP MERTK	3.31e-05	212	124	7	C0015397
Disease	Bipolar Disorder	NTRK2 GRID1 NLGN1 RFX4 CNTN6 FZD4 PTPA KCNN3 ASTN2 FKBP5	3.50e-05	477	124	10	C0005586
Disease	Urinary incontinence	PMVK KCNN3	5.24e-05	3	124	2	HP_0000020
Disease	Meckel syndrome type 1	TMEM67 CEP290 NPHP3	5.64e-05	18	124	3	C3714506
Disease	Familial aplasia of the vermis	TMEM67 CEP290 TTC21B	7.84e-05	20	124	3	cv:C0431399
Disease	Ciliopathies	TMEM67 CEP290 NPHP3 PKD2 TTC21B	1.04e-04	110	124	5	C4277690
Disease	attention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement	NRAP NTRK3 TRPC4 NLGN1 REV3L TENM2 HHLA2 KCNU1 PTPRK FHL2 SDK1 PDE11A	1.46e-04	801	124	12	EFO_0003888, EFO_0007052, MONDO_0002491
Disease	odorant-binding protein 2b measurement	OBP2B OBP2A	1.74e-04	5	124	2	EFO_0801859
Disease	Child Development Disorders, Specific	DOCK8 NTRK2 CHRNA4	2.44e-04	29	124	3	C0085997
Disease	Child Development Deviations	DOCK8 NTRK2 CHRNA4	2.44e-04	29	124	3	C0085996
Disease	PR interval	SUMF2 HCN4 OBSCN RFX4 CNTN6 SERPINB5 CSHL1 ASTN2 FHL2	2.53e-04	495	124	9	EFO_0004462
Disease	nephronophthisis (is_implicated_in)	TMEM67 NPHP3	2.60e-04	6	124	2	DOID:12712 (is_implicated_in)
Disease	Developmental Disabilities	DOCK8 NTRK2 CHRNA4	2.71e-04	30	124	3	C0008073
Disease	smoking behaviour measurement	REV3L TENM2 CHRNA4 ASTN2 FHL2 SDK1	3.62e-04	222	124	6	EFO_0005671
Disease	hepatitis C virus infection, cirrhosis of liver	MERTK FKBP5	3.63e-04	7	124	2	EFO_0001422, EFO_0003047
Disease	adiponectin measurement	COL3A1 RFX4 EGF PTPRK VWA3B	3.89e-04	146	124	5	EFO_0004502
Disease	autism spectrum disorder (implicated_via_orthology)	KDM5C TRPC4 NLGN1 UBE3A NLGN2	4.67e-04	152	124	5	DOID:0060041 (implicated_via_orthology)
Disease	NEPHRONOPHTHISIS 2	NPHP3 TTC21B	4.82e-04	8	124	2	C1865872
Disease	type 1 diabetes mellitus (implicated_via_orthology)	DOCK8 IFNGR2 CSHL1	5.93e-04	39	124	3	DOID:9744 (implicated_via_orthology)
Disease	Malignant neoplasm of breast	EPHB4 TRPC4 OBSCN LDHAL6B UBLCP1 PDCD4 CNTN6 SERPINB5 CADM1 EGF DIP2C ASTN2 FHL2	6.01e-04	1074	124	13	C0006142
Disease	Nephronophthisis	TMEM67 NPHP3	6.19e-04	9	124	2	cv:C0687120
Disease	pyoderma gangrenosum	SERPINB5 USP15	6.19e-04	9	124	2	EFO_0006835
Disease	bile salt-activated lipase measurement	CEL OBP2B	6.19e-04	9	124	2	EFO_0801425
Disease	Unipolar Depression	NTRK2 NTRK3 CADM1 EGF FKBP5 PDE11A	8.13e-04	259	124	6	C0041696
Disease	Gastric Adenocarcinoma	EPHB4 NTRK3 MAP3K9	9.04e-04	45	124	3	C0278701
Disease	Alcoholic Intoxication, Chronic	NTRK2 RFX4 CHRNA4 CNTN6 EGF FKBP5	9.69e-04	268	124	6	C0001973
Disease	Renal dysplasia and retinal aplasia (disorder)	CEP290 NPHP3	1.12e-03	12	124	2	C0403553
Disease	peak expiratory flow	STK32B GRID1 FAM227B CHRNA4 PTPRK SVIL XRN1 ASTN2	1.24e-03	498	124	8	EFO_0009718
Disease	Schizophrenia	COL3A1 NTRK2 NTRK3 GRID1 NLGN1 LMOD2 CHRNA4 PI4KA KCNN3 ASTN2 NLGN2	1.27e-03	883	124	11	C0036341
Disease	Bardet-Biedl Syndrome	TMEM67 CEP290	1.33e-03	13	124	2	C0752166
Disease	platelet component distribution width	COL3A1 EPHB4 SH3TC2 SCN11A DOCK8 ERI1 EGF SVIL USP15 PACSIN2	1.35e-03	755	124	10	EFO_0007984
Disease	alcohol use disorder (implicated_via_orthology)	PPP1R3B KDM5C CHRNA4 KCNU1 ATP1A4	1.43e-03	195	124	5	DOID:1574 (implicated_via_orthology)
Disease	Familial thoracic aortic aneurysm and aortic dissection	COL3A1 HCN4 PKD2	1.46e-03	53	124	3	C4707243
Disease	Polydactyly	TMEM67 CEP290 NPHP3 TTC21B	1.53e-03	117	124	4	C0152427
Disease	aspartate aminotransferase measurement	CEL OBP2B PPP1R3B NTRK2 OBSCN FAM227B ERI1 NPHP3 CADM1 ASTN2 MERTK	1.53e-03	904	124	11	EFO_0004736
Disease	Metastatic melanoma	EPHB4 STK32B MAP3K9	1.54e-03	54	124	3	C0278883
Disease	autosomal dominant polycystic kidney disease (implicated_via_orthology)	NPHP3 PKD2	1.54e-03	14	124	2	DOID:898 (implicated_via_orthology)
Disease	CD209 antigen measurement	OBP2B CLEC4G	1.54e-03	14	124	2	EFO_0008077
Disease	Meckel-Gruber syndrome	TMEM67 CEP290	1.77e-03	15	124	2	C0265215
Disease	adverse effect, response to xenobiotic stimulus	NLGN1 ASTN2 VWA3B	1.98e-03	59	124	3	EFO_0009658, GO_0009410
Disease	celiac disease	STK32B PTPRK MTTP HYDIN	2.00e-03	126	124	4	EFO_0001060
Disease	Alpha ketoglutarate measurement	SAMD9 TENM3	2.02e-03	16	124	2	EFO_0010457
Disease	MAJOR AFFECTIVE DISORDER 2	FZD4 PTPA	2.29e-03	17	124	2	C1839839
Disease	major depressive disorder (is_implicated_in)	NTRK2 FKBP5	2.29e-03	17	124	2	DOID:1470 (is_implicated_in)
Disease	bipolar disorder, sex interaction measurement	TTC39B FHL2	2.56e-03	18	124	2	EFO_0008343, MONDO_0004985
Disease	Bardet-Biedl syndrome	TMEM67 CEP290	2.56e-03	18	124	2	cv:C0752166
Disease	blood lead measurement	NTRK3 CADPS FHL2	2.73e-03	66	124	3	EFO_0007040
Disease	hydrocephalus (implicated_via_orthology)	TMEM67 HYDIN	2.86e-03	19	124	2	DOID:10908 (implicated_via_orthology)
Disease	Vertigo	TTC39B PRDM2 CADPS SVIL	2.86e-03	139	124	4	HP_0002321
Disease	palmitoylcarnitine measurement	ASTN2 ATP1A4	3.49e-03	21	124	2	EFO_0021044
Disease	Major Depressive Disorder	NTRK2 NTRK3 EGF FKBP5 PDE11A	3.70e-03	243	124	5	C1269683
Disease	hip bone mineral density, fat body mass	GRID1 NMT1	3.83e-03	22	124	2	EFO_0005409, EFO_0007702
Disease	Leber Congenital Amaurosis	CEP290 MERTK	3.83e-03	22	124	2	C0339527
Disease	migraine disorder	SCN11A REV3L KLF10 SVIL DIP2C ASTN2	4.07e-03	357	124	6	MONDO_0005277
Disease	Carcinoma of lung	NTRK2 NTRK3	4.18e-03	23	124	2	C0684249
Disease	idiopathic pulmonary fibrosis (is_marker_for)	NTRK2 IL1RL1	4.18e-03	23	124	2	DOID:0050156 (is_marker_for)

Protein segments in the cluster

Peptide	Gene	Start	Entry
WYKTAMTLDETSVSA	TTC21B	346	Q7Z4L5
EIFKWKSMISETSSY	FAM227B	101	Q96M60
TKYKYSLLTDGSWDM	ERI1	221	Q8IV48
TMKFGSWTYDKAKID	CHRNA4	176	P43681
VQWISMAFESTTYKG	DISP3	1116	Q9P2K9
EFISSWGMEAYITKE	CSHL1	56	Q14406
KYWMFTTEDAVKSSA	AASDH	846	Q4L235
YEKSLKMDDSSTIQW	CFAP92	286	Q9ULG3
KYMGRTSFDSDSWTL	CD86	81	P42081
SKAMIAYWTNFAKTG	CEL	481	P19835
GTKEAFKSALMSSYW	ASTN2	1021	O75129
DLQARKWKFEMSYTS	NWD1	1416	Q149M9
AEKASKWYSRFTMYT	DENND4A	1331	Q7Z401
KWYSRFTMYTTSSKD	DENND4A	1336	Q7Z401
YSCVMTGSWDKTLKF	RAE1	141	P78406
WKYSSGFVTADMIKE	CYB5R2	221	Q6BCY4
YDVMYSKKGAAWVSE	RFX4	141	Q33E94
YQGFDTDTWKEMLKF	HACL1	486	Q9UJ83
MWRKKSSDRKGGSYS	HLA-H	331	P01893
ETVLSSWMAKFDAIY	CADPS	231	Q9ULU8
SWLEMEYGLSEKESK	FKBP5	296	Q13451
TSKDWGKMVSLFYGI	OR2B3	266	O76000
TTTETYMGEWKNDKR	JPH2	286	Q9BR39
DLATLKKYWDNGMTS	HDX	446	Q7Z353
SEWASKAKANGITMY	MATN2	776	O00339
FWSEETKSRFTEYSM	LTV1	231	Q96GA3
AKTMEEASKRSYQFW	NMT1	106	P30419
KFTSASDAWSYGIVM	EPHB4	796	P54760
YGMADKVDVKTWKST	MGAT2	301	Q10469
AMNISETRYKESWSK	NRAP	1021	Q86VF7
SIMYRKFTTESDVWS	NTRK3	741	Q16288
VYTSKSDVWAFGVTM	MERTK	776	Q12866
AGKTWTSRCLMKFYA	MYO19	136	Q96H55
TTTETYMGEWKNDKR	JPH1	276	Q9HDC5
TGTFSREALMAYWEK	LMOD2	61	Q6P5Q4
KDSVMWALDGLSFTY	IFNAR1	151	P17181
WKSSTITVDQMKRGY	PDCD4	391	Q53EL6
ETELSWGLYSKDSMF	KCNN3	301	Q9UGI6
WGLYSKDSMFSLALK	KCNN3	306	Q9UGI6
TAYEIIKMKGYTSWA	LDHAL6B	286	Q9BYZ2
ISGAMEFSLWYRESK	MTTP	761	P55157
SFKESMEKSSYSDWL	PDE11A	456	Q9HCR9
WKFTESSKDGMTRVY	FMO4	41	P31512
LSWMIKEEAYFESTS	INTS2	456	Q9H0H0
FKVTWSRMKSGTFSV	HHLA2	256	Q9UM44
WTAMFSDKKYLTASQ	PI4KA	1411	P42356
YTTFISGSAMKWEDL	KCNU1	386	A8MYU2
EKFSGLWYVVSMASD	LCN15	31	Q6UWW0
SAVVMTYWTNFAKTG	NLGN1	576	Q8N2Q7
TGTWYVKAMVVDKDF	OBP2A	26	Q9NY56
KYLKSWFMVDFISSI	HCN4	336	Q9Y3Q4
WAVASSFGNMIYKEK	PANK3	266	Q9H999
TEVMWYKDGKKLSFS	OBSCN	1471	Q5VST9
LGSYSSWSRVMVDSK	NPC1L1	651	Q9UHC9
TGTWYVKAMVVDKDF	OBP2B	26	Q9NPH6
YGTVEKAWMAFMSEA	PACSIN2	76	Q9UNF0
LKGKSEVEEWSDMYT	CADM1	186	Q9BY67
YSRSAKEFTDIWMAV	FZD4	211	Q9ULV1
LKMVAKQWYDFDRSS	HECTD1	1036	Q9ULT8
ILMYSTAAKFSKQSW	IL1RL1	11	Q01638
DYKRPSWTKEEISSM	HYDIN	621	Q4G0P3
STGMVRETVFKYAWF	DOCK8	971	Q8NF50
RKFGIVDSYWKSLMS	DNAH3	1111	Q8TD57
AMSLFGDRIFYSTWK	EGF	251	P01133
ADSKSWKSIVVTRMY	CEP290	2261	O15078
MSFLSVQDKEAGYWK	FBXO15	141	Q8NCQ5
KSSKWDFEEEMTYLG	GCM1	406	Q9NP62
TYGKLWTRSMKVAYS	DIP2C	351	Q9Y2E4
LYWTDDSKESMIGKI	CNTN6	841	Q9UQ52
GTRKMEYKGSSWHET	FHL2	111	Q14192
QFKYTDSKWFTADIM	IFNGR2	66	P38484
YKKEAAMWETLSVTG	DNAAF4	76	Q8WXU2
LTSWGELMKSKYSDI	GAMT	171	Q14353
TGWQYSLKFSEMKIR	FIBCD1	441	Q8N539
YSETFGKDMRKLATW	GRID1	401	Q9ULK0
SMYSWNKTAEKSDFE	KLF10	26	Q13118
TGEWSKTVFEYRTRK	COL3A1	1421	P02461
YQWTKVGDVTAKRMS	ENC1	516	O14682
VNVGTWKSRSTMEKY	DCLRE1A	1016	Q6PJP8
TFSWYREATGTSMGK	FCRL2	236	Q96LA5
FKWMRDDSELTTYSS	SDK1	136	Q7Z5N4
SAVVMTYWTNFAKTG	NLGN2	531	Q8NFZ4
WTMIGSIFSFQSEKK	PEX1	246	O43933
IRASMFSKGSDVWSY	MAP3K9	321	P80192
KVTIKYMWDSQSGRF	MRTO4	201	Q9UKD2
DEYKMSKEWTASSAF	PRDM2	801	Q13029
KIRMTFDTWKSYTDF	PPP1R3B	161	Q86XI6
KEVEYRMTSGSWTET	PTPRK	326	Q15262
EVGMSLTSEWFAKYL	TMEM67	216	Q5HYA8
KKYRTEAEMFGWSFV	SUMF2	81	Q8NBJ7
KPITYMSWDSSTSKE	SLC6A16	636	Q9GZN6
GSSTTKDDYKQWSSM	SAXO1	336	Q8IYX7
YVVKWKFMVSTAVGS	SVIL	1781	O95425
SYWQFVGKDKSAMAT	NPHP3	906	Q7Z494
WGTEKFEDKMGTYST	SAMD9	951	Q5K651
KAVVSSDKSGMIEYW	PPWD1	236	Q96BP3
FRLKSKWMKYGYTSS	SIGLEC6	121	O43699
GSWTDDYCMSKFKNT	SIN3B	431	O75182
GSTSMDLFEAWKKEY	SHPRH	1321	Q149N8
ITFKTMEEIWKFSTY	SH3TC2	111	Q8TF17
IVSRMFADGKVWSYS	TENM2	1921	Q9NT68
YFVGKWMKKFSESET	SERPINB5	166	P36952
STYKEAFRKDMIRWG	PMVK	66	Q15126
RSAYFANMLDTKWKG	ABTB1	136	Q969K4
MWVTSADFKEYGTSV	ACTRT1	356	Q8TDG2
GKTFTKSSDTWFMLA	ATP1A4	416	Q13733
MDTTRYSKWGGSSEE	CLEC4G	1	Q6UXB4
MYRKFTTESDVWSLG	NTRK2	726	Q16620
DIGMFTYDESTKLFW	UBE3A	586	Q05086
MYVWNGFSIVSKRKD	TTC39B	541	Q5VTQ0
KKWGARVVYGDTDSM	REV3L	2771	O60673
FWGLRSYHETSKMKV	TRO	606	Q12816
VDETAFYWKKMPSRT	TIGD1	186	Q96MW7
GKKLTFEYRVSEMWN	PTPA	61	Q15257
YVTFLSKKSSRWPSM	RNF222	66	A6NCQ9
KKVGSEWMYSSAAEQ	XRN1	971	Q8IZH2
SYAELIKQMWSGKFS	USP15	341	Q9Y4E8
DGKTWSYTYLEKSMV	TENM3	1856	Q9P273
KTLSSMEDFWKFTEG	PKD2	271	Q13563
FGKSKEEFYSMATWR	VILL	831	O15195
WGKFSEFYSKKNTIM	UBLCP1	236	Q8WVY7
FKGWMDIIYAAVDST	SCN11A	1256	Q9UI33
KVERVHYSSTWCKGM	STK32B	241	Q9NY57
WDSYATTMRTAFTPK	TEX26	26	Q8N6G2
VESYKQRMDWLTSKS	VWA3B	116	Q502W6
AGEKSVFLWSMRSYT	WSB2	216	Q9NYS7
WDIRTGKVMRSYKAT	WDR25	361	Q64LD2
YWFETKMSALKQSTS	ZNF485	86	Q8NCK3
ERFYQMTGEAWKLSS	UBXN8	116	O00124
KFARTKLWMSYFEEG	TRPC4	636	Q9UBN4
SRWMEKELGLYKSDT	KDM5C	1116	P41229