Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	CCP	SNED1 CSMD2 CR1L CSMD3	2.70e-05	54	60	4	SM00032
Domain	SUSHI	SNED1 CSMD2 CR1L CSMD3	3.12e-05	56	60	4	PS50923
Domain	Sushi_SCR_CCP_dom	SNED1 CSMD2 CR1L CSMD3	3.35e-05	57	60	4	IPR000436
Domain	NIDO_dom	SNED1 NID2	1.01e-04	5	60	2	IPR003886
Domain	NIDO	SNED1 NID2	1.01e-04	5	60	2	SM00539
Domain	NIDO	SNED1 NID2	1.01e-04	5	60	2	PF06119
Domain	NIDO	SNED1 NID2	1.01e-04	5	60	2	PS51220
Domain	EGF	SNED1 NID2 UMODL1 LAMA2 LAMC2 NOTCH1	1.06e-04	235	60	6	SM00181
Domain	EGF-like_dom	SNED1 NID2 UMODL1 LAMA2 LAMC2 NOTCH1	1.45e-04	249	60	6	IPR000742
Domain	EGF-like_CS	SNED1 NID2 UMODL1 LAMA2 LAMC2 NOTCH1	1.87e-04	261	60	6	IPR013032
Domain	EGF_2	SNED1 NID2 UMODL1 LAMA2 LAMC2 NOTCH1	2.03e-04	265	60	6	PS01186
Domain	EGF_Ca-bd_CS	SNED1 NID2 UMODL1 NOTCH1	2.67e-04	97	60	4	IPR018097
Domain	LAMININ_IVA	LAMA2 LAMC2	2.81e-04	8	60	2	PS51115
Domain	Laminin_B	LAMA2 LAMC2	2.81e-04	8	60	2	PF00052
Domain	LamB	LAMA2 LAMC2	2.81e-04	8	60	2	SM00281
Domain	Laminin_IV	LAMA2 LAMC2	2.81e-04	8	60	2	IPR000034
Domain	EGF_CA	SNED1 NID2 UMODL1 NOTCH1	2.88e-04	99	60	4	PS01187
Domain	ASX_HYDROXYL	SNED1 NID2 UMODL1 NOTCH1	3.00e-04	100	60	4	PS00010
Domain	EGF-type_Asp/Asn_hydroxyl_site	SNED1 NID2 UMODL1 NOTCH1	3.74e-04	106	60	4	IPR000152
Domain	Sushi	CSMD2 CR1L CSMD3	6.23e-04	52	60	3	PF00084
Domain	EGF_CA	SNED1 NID2 UMODL1 NOTCH1	6.37e-04	122	60	4	SM00179
Domain	EGF-like_Ca-bd_dom	SNED1 NID2 UMODL1 NOTCH1	6.77e-04	124	60	4	IPR001881
Domain	TY	NID2 TG	1.34e-03	17	60	2	SM00211
Domain	-	NID2 TG	1.34e-03	17	60	2	4.10.800.10
Domain	THYROGLOBULIN_1_2	NID2 TG	1.34e-03	17	60	2	PS51162
Domain	Thyroglobulin_1	NID2 TG	1.34e-03	17	60	2	IPR000716
Domain	Thyroglobulin_1	NID2 TG	1.34e-03	17	60	2	PF00086
Domain	THYROGLOBULIN_1_1	NID2 TG	1.34e-03	17	60	2	PS00484
Domain	EGF_1	SNED1 UMODL1 LAMA2 LAMC2 NOTCH1	1.35e-03	255	60	5	PS00022
Domain	Growth_fac_rcpt_	NID2 UMODL1 LAMC2 NOTCH1	1.59e-03	156	60	4	IPR009030
Domain	EGF_CA	NID2 UMODL1 NOTCH1	2.67e-03	86	60	3	PF07645
Domain	Ephrin_rec_like	TNFRSF4 TG	2.90e-03	25	60	2	SM01411
Domain	Tyr-kin_ephrin_A/B_rcpt-like	TNFRSF4 TG	2.90e-03	25	60	2	IPR011641
Domain	FN3	SNED1 FLNC NEO1 UMODL1	2.95e-03	185	60	4	SM00060
Domain	Bromodomain_CS	ATAD2B BRWD1	3.14e-03	26	60	2	IPR018359
Domain	hEGF	SNED1 NOTCH1	3.64e-03	28	60	2	PF12661
Domain	EGF_LAM_2	LAMA2 LAMC2	4.17e-03	30	60	2	PS50027
Domain	EGF_LAM_1	LAMA2 LAMC2	4.17e-03	30	60	2	PS01248
Domain	FN3_dom	SNED1 FLNC NEO1 UMODL1	4.56e-03	209	60	4	IPR003961
Domain	Ig_E-set	TGM2 FLNC ARRB1	4.56e-03	104	60	3	IPR014756
Domain	CNMP_BINDING_1	KCNH6 PNPLA6	4.73e-03	32	60	2	PS00888
Domain	CNMP_BINDING_2	KCNH6 PNPLA6	4.73e-03	32	60	2	PS00889
Domain	cNMP	KCNH6 PNPLA6	5.33e-03	34	60	2	SM00100
Domain	cNMP_binding	KCNH6 PNPLA6	5.33e-03	34	60	2	PF00027
Domain	cNMP-bd_dom	KCNH6 PNPLA6	5.64e-03	35	60	2	IPR000595
Domain	CNMP_BINDING_3	KCNH6 PNPLA6	5.64e-03	35	60	2	PS50042
Domain	Laminin_EGF	LAMA2 LAMC2	5.64e-03	35	60	2	PF00053
Domain	EGF_Lam	LAMA2 LAMC2	5.64e-03	35	60	2	SM00180
Domain	Ion_trans_dom	CACNA1B KCNH6 KCNU1	5.89e-03	114	60	3	IPR005821
Domain	Ion_trans	CACNA1B KCNH6 KCNU1	5.89e-03	114	60	3	PF00520
Domain	BROMODOMAIN_1	ATAD2B BRWD1	6.29e-03	37	60	2	PS00633
Pathway	REACTOME_MET_ACTIVATES_PTK2_SIGNALING	LAMA2 LAMC2 PTK2	1.24e-04	30	46	3	M27772
Pathway	REACTOME_LAMININ_INTERACTIONS	NID2 LAMA2 LAMC2	1.24e-04	30	46	3	M27216
Pathway	KEGG_SMALL_CELL_LUNG_CANCER	LAMA2 LAMC2 AKT2 PTK2	1.58e-04	84	46	4	M3228
Pathway	WP_ALPHA_6_BETA_4_SIGNALING	LAMA2 LAMC2 PTK2	1.66e-04	33	46	3	M39503
Pathway	WP_SMALL_CELL_LUNG_CANCER	LAMA2 LAMC2 AKT2 PTK2	2.65e-04	96	46	4	M39834
Pathway	REACTOME_MET_PROMOTES_CELL_MOTILITY	LAMA2 LAMC2 PTK2	3.18e-04	41	46	3	M27778
Pubmed	Basement membrane composition in the early mouse embryo day 7.	NID2 LAMA2 LAMC2	2.30e-06	15	61	3	15895400
Pubmed	Focal adhesion kinase is a component of antiviral RIG-I-like receptor signaling.	MAVS PTK2	3.03e-06	2	61	2	22341464
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	TGM2 NEO1 IGF2R MAVS GPATCH11 RNF149 NUCKS1 UNK AKT2	5.09e-06	733	61	9	34672954
Pubmed	The ARE-dependent mRNA-destabilizing activity of BRF1 is regulated by protein kinase B.	BRF1 AKT2	9.07e-06	3	61	2	15538381
Pubmed	Identification of two new members of the CSMD gene family.	CSMD2 CSMD3	9.07e-06	3	61	2	12906867
Pubmed	Downregulation of Notch1 inhibits the invasion of human hepatocellular carcinoma HepG2 and MHCC97H cells through the regulation of PTEN and FAK.	NOTCH1 PTK2	9.07e-06	3	61	2	25110169
Pubmed	CircPTK2 accelerates tumorigenesis of colorectal cancer by upregulating AKT2 expression via miR-506-3p.	AKT2 PTK2	9.07e-06	3	61	2	36156852
Pubmed	Laminin isoforms in development and disease.	LAMA2 LAMC2	9.07e-06	3	61	2	17426950
Pubmed	Focal adhesion kinase in netrin-1 signaling.	NEO1 PTK2	1.81e-05	4	61	2	15494733
Pubmed	SchA-p85-FAK complex dictates isoform-specific activation of Akt2 and subsequent PCBP1-mediated post-transcriptional regulation of TGFβ-mediated epithelial to mesenchymal transition in human lung cancer cell line A549.	AKT2 PTK2	1.81e-05	4	61	2	24819169
Pubmed	Laminin α2-mediated focal adhesion kinase activation triggers Alport glomerular pathogenesis.	LAMA2 PTK2	1.81e-05	4	61	2	24915008
Pubmed	Role of receptor for hyaluronic acid-mediated motility (RHAMM) in low molecular weight hyaluronan (LMWHA)-mediated fibrosarcoma cell adhesion.	HMMR PTK2	1.81e-05	4	61	2	21914806
Pubmed	β-Arrestin1 and Signal-transducing Adaptor Molecule 1 (STAM1) Cooperate to Promote Focal Adhesion Kinase Autophosphorylation and Chemotaxis via the Chemokine Receptor CXCR4.	ARRB1 PTK2	1.81e-05	4	61	2	27789711
Pubmed	ARRB1-Promoted NOTCH1 Degradation Is Suppressed by OncomiR miR-223 in T-cell Acute Lymphoblastic Leukemia.	ARRB1 NOTCH1	1.81e-05	4	61	2	31822496
Pubmed	Binding of the G domains of laminin alpha1 and alpha2 chains and perlecan to heparin, sulfatides, alpha-dystroglycan and several extracellular matrix proteins.	NID2 LAMA2	1.81e-05	4	61	2	10022829
Pubmed	Basement membrane assembly of the integrin α8β1 ligand nephronectin requires Fraser syndrome-associated proteins.	NID2 LAMA2 LAMC2	1.82e-05	29	61	3	22613833
Pubmed	Differential effects of extracellular ATP on chloride transport in cortical collecting duct cells.	CLCA4 SCNN1G	3.02e-05	5	61	2	22647633
Pubmed	Short arm region of laminin-5 gamma2 chain: structure, mechanism of processing and binding to heparin and proteins.	NID2 LAMC2	3.02e-05	5	61	2	11733994
Pubmed	Genetic variants at 1q32.1, 10q11.2 and 19q13.41 are associated with prostate-specific antigen for prostate cancer screening in two Korean population-based cohort studies.	KLK15 NUCKS1	4.52e-05	6	61	2	25434496
Pubmed	Α-arrestin 1 (ARRDC1) and β-arrestins cooperate to mediate Notch degradation in mammals.	ARRB1 NOTCH1	4.52e-05	6	61	2	23886940
Pubmed	Mice carrying a complete deletion of the talin2 coding sequence are viable and fertile.	LAMA2 PTK2	4.52e-05	6	61	2	22925892
Pubmed	A synaptic nidogen: developmental regulation and role of nidogen-2 at the neuromuscular junction.	NID2 LAMA2	4.52e-05	6	61	2	18817539
Pubmed	Contribution of the PI3K/MMPs/Ln-5γ2 and EphA2/FAK/Paxillin signaling pathways to tumor growth and vasculogenic mimicry of gallbladder carcinomas.	LAMC2 PTK2	4.52e-05	6	61	2	23588386
Pubmed	Mechanistic role of transglutaminase-2 in focal adhesions.	TGM2 PTK2	4.52e-05	6	61	2	30120307
Pubmed	Frequent provirus insertional mutagenesis of Notch1 in thymomas of MMTVD/myc transgenic mice suggests a collaboration of c-myc and Notch1 for oncogenesis.	CACNA1B NOTCH1	4.52e-05	6	61	2	8756350
Pubmed	Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly.	LAMA2 LAMC2 TG	4.84e-05	40	61	3	27068110
Pubmed	Cloning and expression analysis of the mouse stroma marker Snep encoding a novel nidogen domain protein.	SNED1 NID2	6.32e-05	7	61	2	15162516
Pubmed	Neogenin regulates skeletal myofiber size and focal adhesion kinase and extracellular signal-regulated kinase activities in vivo and in vitro.	NEO1 PTK2	8.42e-05	8	61	2	19812254
Pubmed	Mouse histamine N-methyltransferase: cDNA cloning, expression, gene cloning and chromosomal localization.	CACNA1B NOTCH1	8.42e-05	8	61	2	11475331
Pubmed	Cloning and expression analyses of mouse dystroglycan gene: specific expression in maternal decidua at the peri-implantation stage.	LAMA2 LAMC2	8.42e-05	8	61	2	8872465
Pubmed	L-serine deficiency caused by genetic Phgdh deletion leads to robust induction of 4E-BP1 and subsequent repression of translation initiation in the developing central nervous system.	DDIT3 NOTCH1	8.42e-05	8	61	2	23350942
Pubmed	Mouse kalinin B1 (laminin beta 3 chain): cloning and tissue distribution.	LAMC2 CR1L	8.42e-05	8	61	2	7898049
Pubmed	Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.	NID2 TGM2 LAMA2 LAMC2	9.54e-05	135	61	4	28675934
Pubmed	Selective inhibition of prostaglandin E2 receptors EP2 and EP4 inhibits adhesion of human endometriotic epithelial and stromal cells through suppression of integrin-mediated mechanisms.	ARRB1 PTK2	1.35e-04	10	61	2	23242524
Pubmed	Trophoblast-specific expression and function of the integrin alpha 7 subunit in the peri-implantation mouse embryo.	LAMA2 LAMC2	1.35e-04	10	61	2	11784026
Pubmed	Distribution of the ten known laminin chains in the pathways and targets of developing sensory axons.	LAMA2 LAMC2	1.35e-04	10	61	2	9034910
Pubmed	Large-scale screen for genes controlling mammalian embryogenesis, using high-throughput gene expression analysis in mouse embryos.	NID2 FLNC WNT7A NOTCH1	1.51e-04	152	61	4	11044609
Pubmed	Mutations in LAMB1 cause cobblestone brain malformation without muscular or ocular abnormalities.	LAMA2 LAMC2	1.65e-04	11	61	2	23472759
Pubmed	Hydrocephalus in mouse B3glct mutants is likely caused by defects in multiple B3GLCT substrates in ependymal cells and subcommissural organ.	ADAMTS20 DDIT3	1.65e-04	11	61	2	33909046
Pubmed	Basement membrane deposition of nidogen 1 but not nidogen 2 requires the nidogen binding module of the laminin gamma1 chain.	NID2 LAMC2	1.65e-04	11	61	2	21084308
Pubmed	Regional differences in the expression of laminin isoforms during mouse neural tube development.	LAMA2 LAMC2	1.65e-04	11	61	2	21524702
Pubmed	A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.	ILF3 IGF2R CENPF GPATCH11 NUCKS1 HMMR	1.79e-04	472	61	6	38943005
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	CACNA1B ILF3 NUCKS1 UNK LMTK3 PTK2	1.85e-04	475	61	6	31040226
Pubmed	Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins.	LMTK3 CSMD2 CSMD3	1.89e-04	63	61	3	11572484
Pubmed	Wnt5a Deficiency Leads to Anomalies in Ureteric Tree Development, Tubular Epithelial Cell Organization and Basement Membrane Integrity Pointing to a Role in Kidney Collecting Duct Patterning.	LAMA2 LAMC2	1.97e-04	12	61	2	26794322
Pubmed	Functionally distinct PI 3-kinase pathways regulate myelination in the peripheral nervous system.	LAMA2 AKT2	1.97e-04	12	61	2	24687281
Pubmed	Distribution and function of laminins in the neuromuscular system of developing, adult, and mutant mice.	LAMA2 LAMC2	1.97e-04	12	61	2	9396756
Pubmed	Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.	NID2 LAMA2 ADAMTS20	1.98e-04	64	61	3	22261194
Pubmed	Rescue of deficits by Brwd1 copy number restoration in the Ts65Dn mouse model of Down syndrome.	ACTL6B BRWD1	2.72e-04	14	61	2	36289231
Pubmed	ADAR1 interaction with Z-RNA promotes editing of endogenous double-stranded RNA and prevents MDA5-dependent immune activation.	MAVS DDIT3	2.72e-04	14	61	2	34380029
Pubmed	Chemokine coreceptor signaling in HIV-1 infection and pathogenesis.	AKT2 PTK2	2.72e-04	14	61	2	20041213
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	KLK15 KCNH6 TGM2 ILF3 KAT6A AKT2 PTK2	2.85e-04	730	61	7	34857952
Pubmed	Laminin alpha5 chain is required for intestinal smooth muscle development.	LAMA2 LAMC2	3.13e-04	15	61	2	12921739
Pubmed	Localization of basement membrane-associated protein isoforms during development of the ocular surface of mouse eye.	LAMA2 LAMC2	3.13e-04	15	61	2	9264260
Pubmed	Extracellular Matrix Disorganization Caused by ADAMTS16 Deficiency Leads to Bicuspid Aortic Valve With Raphe Formation.	NOTCH1 PTK2	3.13e-04	15	61	2	38018454
Pubmed	A high-resolution molecular atlas of the fetal mouse lower urogenital tract.	ILF3 WNT7A PTK2	3.17e-04	75	61	3	21905163
Pubmed	Differentiation of the ductal epithelium and smooth muscle in the prostate gland are regulated by the Notch/PTEN-dependent mechanism.	AKT2 NOTCH1	3.57e-04	16	61	2	21624358
Pubmed	Laminin alpha5 is necessary for submandibular gland epithelial morphogenesis and influences FGFR expression through beta1 integrin signaling.	LAMA2 LAMC2	3.57e-04	16	61	2	17601529
Pubmed	Genomic analysis of mouse retinal development.	ILF3 WNT7A NUCKS1 UNK GBA2 DDIT3 NOTCH1 PTK2	3.61e-04	1006	61	8	15226823
Pubmed	Transcriptome-based systematic identification of extracellular matrix proteins.	NID2 LAMA2 LAMC2	3.69e-04	79	61	3	18757743
Pubmed	Laminin α1 is essential for mouse cerebellar development.	LAMA2 PTK2	4.05e-04	17	61	2	21983115
Pubmed	A genome-wide meta-analysis of association studies of Cloninger's Temperament Scales.	CSMD3 TG	4.05e-04	17	61	2	22832960
Pubmed	A direct functional link between the multi-PDZ domain protein GRIP1 and the Fraser syndrome protein Fras1.	LAMA2 LAMC2	4.55e-04	18	61	2	14730302
Pubmed	Amplification of extracellular matrix and oncogenes in tat-transfected human salivary gland cell lines with expression of laminin, fibronectin, collagens I, III, IV, c-myc and p53.	LAMA2 LAMC2	4.55e-04	18	61	2	11311202
Pubmed	Laminin and integrin expression in the ventral ectodermal ridge of the mouse embryo: implications for regulation of BMP signalling.	LAMA2 LAMC2	5.63e-04	20	61	2	22911573
Pubmed	High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men.	ARRB1 IGF2R WNT7A AKT2 NOTCH1	5.66e-04	383	61	5	19453261
Pubmed	Feedback regulation of apical progenitor fate by immature neurons through Wnt7-Celsr3-Fzd3 signalling.	WNT7A NOTCH1	6.22e-04	21	61	2	26939553
Pubmed	Putative complement control protein CSMD3 dysfunction impairs synaptogenesis and induces neurodevelopmental disorders.	LAMA2 CSMD3	6.83e-04	22	61	2	35245678
Pubmed	TUBB1 mutations cause thyroid dysgenesis associated with abnormal platelet physiology.	DDIT3 TG	6.83e-04	22	61	2	30446499
Pubmed	Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	INTU MAVS ATAD2B	8.01e-04	103	61	3	10574462
Pubmed	Endothelial cell-derived GABA signaling modulates neuronal migration and postnatal behavior.	WNT7A NOTCH1	8.15e-04	24	61	2	29086765
Pubmed	HBO1 is required for H3K14 acetylation and normal transcriptional activity during embryonic development.	KAT6A NOTCH1	8.15e-04	24	61	2	21149574
Pubmed	A protein interaction landscape of breast cancer.	TGM2 ILF3 IGF2R PNPLA6 LAMC2 AKT2	8.50e-04	634	61	6	34591612
Pubmed	Effect of N-(3-phenyl-2-propenyl)-1-deoxynojirimycin on the lectin binding to HIV-1 glycoproteins.	GBA2 ALG13	8.84e-04	25	61	2	2283726
Pubmed	Genes and microRNAs associated with mouse cleft palate: A systematic review and bioinformatics analysis.	IGF2R ADAMTS20	8.84e-04	25	61	2	29475039
Pubmed	Atrx deficiency induces telomere dysfunction, endocrine defects, and reduced life span.	IGF2R TG	8.84e-04	25	61	2	23563309
Pubmed	Site-specific N-glycosylation and oligosaccharide structures of recombinant HIV-1 gp120 derived from a baculovirus expression system.	GBA2 ALG13	9.57e-04	26	61	2	8218172
Pubmed	Cannabinoid inhibits HIV-1 Tat-stimulated adhesion of human monocyte-like cells to extracellular matrix proteins.	LAMA2 LAMC2	9.57e-04	26	61	2	24742657
Pubmed	Large-scale phosphomimetic screening identifies phospho-modulated motif-based protein interactions.	IGF2R MAVS PTK2	9.69e-04	110	61	3	37219487
Pubmed	HIV-1 Tat protein down-regulates CREB transcription factor expression in PC12 neuronal cells through a phosphatidylinositol 3-kinase/AKT/cyclic nucleoside phosphodiesterase pathway.	PDE3B AKT2	1.03e-03	27	61	2	11156964
Pubmed	Novel interactors and a role for supervillin in early cytokinesis.	CENPF HMMR	1.11e-03	28	61	2	20309963
Pubmed	A comprehensive proteomics-based interaction screen that links DYRK1A to RNF169 and to the DNA damage response.	SNED1 TGM2 CENPF	1.19e-03	118	61	3	30979931
Pubmed	SMRT-mediated repression of an H3K27 demethylase in progression from neural stem cell to neuron.	WNT7A NOTCH1	1.19e-03	29	61	2	17928865
Pubmed	Integrin linked kinase (ILK) is required for lens epithelial cell survival, proliferation and differentiation.	AKT2 PTK2	1.28e-03	30	61	2	24472646
Pubmed	Mutation of LRP1 in cardiac neural crest cells causes congenital heart defects by perturbing outflow lengthening.	NOTCH1 PTK2	1.36e-03	31	61	2	32546759
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	TCP11 UNK AKT2 ATP11A GBA2 LRRC71 MTSS2 ALG13	1.42e-03	1242	61	8	30973865
Pubmed	Differential gene expression profiling of the molar tooth germ in peroxisome proliferator-activated receptor-alpha (PPAR-alpha) knockout mouse and in wild-type mouse: molar tooth phenotype of PPAR-alpha knockout mouse.	CACNA1B LAMC2	1.45e-03	32	61	2	19320717
Pubmed	Substrate trapping proteomics reveals targets of the βTrCP2/FBXW11 ubiquitin ligase.	FLNC ILF3 MTSS2	1.50e-03	128	61	3	25332235
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	TGM2 ILF3 PNPLA6 DSG3 CENPF LAMC2 HMMR METAP2	1.53e-03	1257	61	8	36526897
Pubmed	APC haploinsufficiency coupled with p53 loss sufficiently induces mucinous cystic neoplasms and invasive pancreatic carcinoma in mice.	AKT2 NOTCH1	1.64e-03	34	61	2	26411367
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	FLNC ILF3 UNK HMMR METAP2 PTK2	1.67e-03	724	61	6	36232890
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	SNED1 CSMD2 CR1L CSMD3	9.09e-06	57	42	4	1179
GeneFamily	Laminin subunits	LAMA2 LAMC2	3.43e-04	12	42	2	626
Coexpression	GSE22886_CD8_VS_CD4_NAIVE_TCELL_DN	ILF3 WNT7A AKT2 ATP11A PTK2 MTSS2	6.39e-06	196	61	6	M4404
Coexpression	MOREIRA_RESPONSE_TO_TSA_DN	WNT7A METAP2 NOTCH1	9.55e-06	18	61	3	M3506
ToppCell	COVID-19-kidney-Technical/muscle_(Mes)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CACNA1B KCNU1 ADAMTS20 CSMD2 CSMD3	1.85e-06	148	61	5	d6ac5972267254651dfbe16bb4e9a62228093cc7
ToppCell	NS-moderate-d_07-13-Epithelial-FOXN4+\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	INTU CFAP54 CENPF CEP152 LRRC71	2.47e-06	157	61	5	410c9d74a2085179cfb39853cb6d330fa98c9c1b
ToppCell	ASK440-Epithelial-Transformed_epithelium\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	NID2 INTU FEZ1 LAMA2 C16orf46	3.85e-06	172	61	5	df3800bcd9777d02900eba0cfc26ab73de8a1d95
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-1\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NID2 FLNC KCNU1 FEZ1 AKT2	4.08e-06	174	61	5	1d157f7a919c8246e83d8060d2a0017c6c781ef3
ToppCell	ASK440-Epithelial-Transformed_epithelium\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	NID2 FLNC FEZ1 LAMA2 C16orf46	4.56e-06	178	61	5	86f1741636ed3e85bb4a65f84949b718fc38c290
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_low-phase\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TGM2 CENPF WNT7A LAMC2 HMMR	4.94e-06	181	61	5	e0c46e2d52c97893e5894a51d2699e8a8a11eefc
ToppCell	mild-Myeloid-Neutrophils_1\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	PDE3B IGF2R RNF149 DDIT3 NOTCH1	5.35e-06	184	61	5	1a0e8b20b3ac8416d05c2d5934ab4ac80be4cce5
ToppCell	control-Myeloid-Neutrophils_1\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	PDE3B IGF2R RNF149 DDIT3 NOTCH1	6.42e-06	191	61	5	db1b3cd07d7d190155b2d14e82e1d124975fbd0b
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SNED1 TGM2 PDE3B LAMA2 CSMD3	6.92e-06	194	61	5	011e14d9ed1393275f892060e7708ffadcd0767f
ToppCell	Endothelial-Endothelial-H_(cycle)\|Endothelial / shred on cell class and cell subclass (v4)	CLCA4 CENPF NUCKS1 HMMR	3.86e-05	138	61	4	a1f41a5a9da40adcc343722baef78c603599c3f0
ToppCell	E18.5-samps-Epithelial-Alveolar_epithelial-AT1_-_meso\|E18.5-samps / Age Group, Lineage, Cell class and subclass	SCNN1G LAMC2 LMTK3 TNFRSF4	4.32e-05	142	61	4	77fd145c1c500d580f70ac4e54c3fd879ecf0ab3
ToppCell	LPS-IL1RA-Myeloid-Monocytes,_Macrophages-Erythroid\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CENPF ACTL6B CR1L PRDM14	4.56e-05	144	61	4	7c471e332f87d60f4dbed01f3e66bf39995218d0
ToppCell	E16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-matrix_-_immature_3\|E16.5-samps / Age Group, Lineage, Cell class and subclass	NEO1 IGF2R TCP11 HMMR	5.21e-05	149	61	4	651494e84be03dc7b061ebdfa91756a1c507b9b4
ToppCell	facs-Large_Intestine-Distal-3m-Epithelial-epithelial_cell_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLCA4 FEZ1 CENPF NOTCH1	6.07e-05	155	61	4	0e24e767a3895d31d34cabeaca0354aadae34e44
ToppCell	facs-Large_Intestine-Distal-3m-Epithelial-Lgr5-_amplifying_undifferentiated_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLCA4 FEZ1 CENPF NOTCH1	6.07e-05	155	61	4	f3489a548a2c0cc2d9117ff85865c6089ea0835d
ToppCell	Adult-Mesenchymal-myofibroblast_cell-D175\|Adult / Lineage, Cell type, age group and donor	NID2 FEZ1 LAMA2 CSMD2	7.03e-05	161	61	4	048b7dc00746987a24bf870d4d278c4183eb04a2
ToppCell	P15-Mesenchymal-developing_mesenchymal_cell-mesenchymal_mature_unknown_2\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	TGM2 KCNU1 FEZ1 AKT2	7.38e-05	163	61	4	e393e5ff885a42b2b44e430d3d5a58f5e50eb732
ToppCell	E18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PDE3B CENPF NUCKS1 HMMR	7.73e-05	165	61	4	1dcd6b8aa192baeaa1f7bb334843edab6049b96f
ToppCell	normal_Pleural_Fluid-Myeloid_cells-mo-Mac\|Myeloid_cells / Location, Cell class and cell subclass	FEZ1 CENPF LAMC2 HMMR	7.92e-05	166	61	4	d16af6570806ed2880bd0efb5298932fd2a89cf5
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CENPF NUCKS1 HMMR TNFRSF4	7.92e-05	166	61	4	a41a20cef053c67da2d435e3e132ce28f1661c03
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1B KCNU1 CSMD2 CSMD3	8.10e-05	167	61	4	3edb0570e583bb527165bcd8a4c25a042054043b
ToppCell	PND10-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CENPF RNF149 HMMR TG	8.10e-05	167	61	4	a90f905ef38437752e2b0b71bd0322a184de1861
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CENPF TCP11 CEP152 HMMR	8.29e-05	168	61	4	a7eb28e15b591997f1aee09501cb20ae18beca08
ToppCell	normal_Lung-Fibroblasts-Pericytes\|Fibroblasts / Location, Cell class and cell subclass	IGF2R SCNN1G PTK2 MTSS2	8.68e-05	170	61	4	d69c0ea4cb6b204f19d0a5d2164afb42184779ac
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CENPF HMMR TNFRSF4 TG	9.08e-05	172	61	4	282017db72d0537ac82aecc69393ccde9590be60
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-epithelial_cell_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLCA4 CENPF CEP152 NOTCH1	9.29e-05	173	61	4	a5172dee859bf6c2eed46c48bd64dfef0ff9f28f
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-Lgr5-_amplifying_undifferentiated_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLCA4 CENPF CEP152 NOTCH1	9.29e-05	173	61	4	639b5b0b33ce5aa0bc26363c059717012ddc14c0
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_G2M\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IGF2R CENPF HMMR CSMD3	9.71e-05	175	61	4	fa16c6ba08dc0cc22e8cf049db0577811d080df6
ToppCell	(01)_Cycling_Basal_(homeostasis)\|World / shred by cell type and Timepoint	CENPF NUCKS1 HMMR NOTCH1	1.01e-04	177	61	4	05c57578142a6662f18b294d5cc11e6efd6b0f8e
ToppCell	NS-moderate-d_0-4-Lymphoid-NKT-proliferating\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CENPF SCNN1G CEP152 HMMR	1.01e-04	177	61	4	174c54acfe19e2bb31418d69e228032ba724cbb6
ToppCell	facs-Lung-EPCAM-3m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNC BRF1 FEZ1 LAMA2	1.04e-04	178	61	4	27497dbfcf9bb4dd0bf7caa0bd78c7e85f5c18ee
ToppCell	facs-Lung-EPCAM-3m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNC BRF1 FEZ1 LAMA2	1.04e-04	178	61	4	d348a9550db940d204706529759dc51e30506b5f
ToppCell	droplet-Kidney-nan-3m-Mesenchymal-podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NID2 FEZ1 LAMA2 MTSS2	1.11e-04	181	61	4	0b1e7335648823b1d83bdfa878ccd44efe7bba9a
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCP11 SCNN1G ADAMTS20 LAMC2	1.11e-04	181	61	4	7af469f5bcb9b1ab3f35b2758bf2afb87e8eba57
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNC TCP11 STPG2 LRRC71	1.18e-04	184	61	4	264e14aa1859cfc0ed5fb40e97ea189aed9ef4a5
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNC TCP11 STPG2 LRRC71	1.18e-04	184	61	4	d7eccbd21c480d907fdc8eff2bf5ae22ae452221
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Lgr5+_undifferentiated_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLCA4 ILF3 HMMR NOTCH1	1.18e-04	184	61	4	e7b9c69fc77040c5191ad8089697051e2589c30e
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Epithelial-neuroepithelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNC TCP11 STPG2 LRRC71	1.18e-04	184	61	4	22010cfe0428ebfa40952cc1a1a12ad3d25b35c9
ToppCell	PBMC-Mild-cDC_9\|Mild / Compartment, Disease Groups and Clusters	CACNA1B CENPF HMMR CR1L	1.18e-04	184	61	4	2e0c9a2c40c892a2d435eafb31f1f838de9baf15
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TGM2 CENPF WNT7A HMMR	1.20e-04	185	61	4	4d0f3d86fab02c80093e62cb0c79c586c13c5412
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PDE3B CENPF CEP152 HMMR	1.25e-04	187	61	4	057569c9437219ecc396aa6e673b1178a2273837
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	WNT7A SCNN1G LAMC2 ATP11A	1.28e-04	188	61	4	e9cef856a96a97afac5ecafe2ee91eff0d731e01
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like_Prolif-E\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	KCNU1 CENPF CEP152 CSMD3	1.28e-04	188	61	4	0476d7ee3e0ce78c3c5b111e9ade01098f9ea7ec
ToppCell	(2)_Fibroblasts-(20)_Fibro-1\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	SNED1 FLNC FEZ1 LAMA2	1.28e-04	188	61	4	409a7b69d02e87084ca955e3fe6c77230dee8861
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-intestinal_crypt_stem_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLCA4 ILF3 HMMR NOTCH1	1.33e-04	190	61	4	52c59001a079c76249abbaa3141e9e661b83d9a0
ToppCell	(02)_Cycling_Basal_(regeneration)\|World / shred by cell type and Timepoint	CENPF NUCKS1 HMMR NOTCH1	1.33e-04	190	61	4	53f017a11ca5ebe9025558e12cedc409cab2e5aa
ToppCell	Mild-T/NK_proliferative\|World / Disease group and Cell class	CENPF TCP11 CEP152 HMMR	1.36e-04	191	61	4	9dba5526fd5ea8065ad305feb2ee562335f887c6
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like-ILC3\|lymph-node_spleen / Manually curated celltypes from each tissue	TGM2 NEO1 MTSS2 TNFRSF4	1.39e-04	192	61	4	e16035b3328f9b1b2e28d234c62ba88387540550
ToppCell	Healthy_donor-CD4+_Tcm\|World / disease group, cell group and cell class (v2)	SNED1 PDE3B WNT7A TNFRSF4	1.39e-04	192	61	4	1603903454ba6bf65c8e13ede620e0b1e8fbd7ec
ToppCell	NS-critical-d_0-4-Epithelial-Basal\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CLCA4 BRF1 NUCKS1 LMTK3	1.41e-04	193	61	4	1affb4c2e21712bde0d36ab736411fe36642cc6d
ToppCell	droplet-Heart-HEART-1m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNC IGF2R TCP11 NOTCH1	1.41e-04	193	61	4	d0a5f212f8e8a13dbbe3e41df92548ef82eef70b
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	NID2 FLNC NEO1 CSMD3	1.41e-04	193	61	4	cd45118ced91b10baed3b1068d4673ec99824b86
ToppCell	Macrophages-SSc-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	TGM2 PNPLA6 RNF149 NOTCH1	1.41e-04	193	61	4	642f8f20e5a35a4b5d1fc8d3f1e3b9b83a37a654
ToppCell	(3)_Chondrocytes-(33)_Chondro-prol/rest\|(3)_Chondrocytes / Cell class and subclass of bone marrow stroma cells in homeostatis	NID2 CENPF NUCKS1 HMMR	1.44e-04	194	61	4	4a207630d72059345b10010f5cfd3b1462458324
ToppCell	E15.5-Mesenchymal-developing_mesenchymal_cell\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	IGF2R CENPF NUCKS1 HMMR	1.44e-04	194	61	4	d840c1949c328779426c9172e02da09e968f0567
ToppCell	COVID-19-T_cells-Cycling_NK/T_cells\|COVID-19 / group, cell type (main and fine annotations)	CENPF CEP152 HMMR CR1L	1.47e-04	195	61	4	764ed100c28d9bc93ee5ecabc5291c8f184d78da
ToppCell	BLOOD--(1)_Activated_T_cells\| / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	CENPF HMMR NOTCH1 TNFRSF4	1.47e-04	195	61	4	45515d5da8a8c8242eb70a1bea24fe44eca5407b
ToppCell	Epithelial-Epithelial-A_(AT1)\|Epithelial / shred on cell class and cell subclass (v4)	TGM2 WNT7A SCNN1G LAMC2	1.50e-04	196	61	4	41b21a18125cc95bc8adde3369e4abd029cf137d
ToppCell	droplet-Heart-nan-18m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INTU ARRB1 IGF2R NOTCH1	1.50e-04	196	61	4	e386526332138e636aef2542c11316347a45689c
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CLCA4 DSG3 CENPF LAMC2	1.53e-04	197	61	4	fb272c9c60ee3d980e528044dc567b4925a23da6
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CLCA4 DSG3 CENPF HMMR	1.53e-04	197	61	4	1d4ccca2ff46fccb3ac052b5148cb7f94231d65a
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CLCA4 DSG3 CENPF LAMC2	1.53e-04	197	61	4	61c0d78b29dc4ad8a84172cbfcdab03f31351d0e
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CLCA4 DSG3 CENPF LAMC2	1.53e-04	197	61	4	dcabea5c50c133c9a4e294e447462d0393174ea7
ToppCell	Parenchymal-10x5prime-Epithelial-Epi_airway_basal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CLCA4 DSG3 SCNN1G LAMC2	1.53e-04	197	61	4	de772bd2b4cda843777ac879b1087e6444199dfb
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_ciliated-Deuterosomal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CFAP54 CENPF HMMR LRRC71	1.53e-04	197	61	4	6e4a411ef823ce9e16f420e185e21fa19d13af34
ToppCell	Biopsy_IPF-Epithelial-AT1\|Biopsy_IPF / Sample group, Lineage and Cell type	WNT7A SCNN1G LAMC2 ATP11A	1.56e-04	198	61	4	75bdecbe111fededf6082b11de18b84ca308ef6d
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_1-AT1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	NID2 WNT7A SCNN1G LAMC2	1.56e-04	198	61	4	5a85c286f79cde5811d2595a3397c6fb7685adee
ToppCell	cycling_basal_cell\|World / shred by cell class for bronchial biopsy	CENPF NUCKS1 HMMR NOTCH1	1.56e-04	198	61	4	d5306121a75c5eb37d62c353799a98e6ba5ab63f
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SNED1 NID2 TGM2 CSMD3	1.56e-04	198	61	4	09be07ebfc3e49c3858e9b74605b69cf4fc28b56
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1-AT1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	NID2 WNT7A SCNN1G LAMC2	1.56e-04	198	61	4	1282db321e27499d310339d6383974614e295a20
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CLCA4 DSG3 CENPF LAMC2	1.56e-04	198	61	4	e06d41a7254a09e037ec404be2d8c352d5cbd7f4
ToppCell	Control_saline-Epithelial_alveolar-AT_1-Differentiating_AT1\|Control_saline / Treatment groups by lineage, cell group, cell type	NID2 SCNN1G LAMC2 ATP11A	1.56e-04	198	61	4	85f424cd9bb3117c9e322031024aabb87696ce47
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-Basal_2-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CLCA4 WNT7A LAMC2 CSMD3	1.56e-04	198	61	4	a54ae5275a510b49d7629f0908817a0c5f05020e
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-Basal_2\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	CLCA4 WNT7A LAMC2 CSMD3	1.56e-04	198	61	4	34997e3896d0893fbe51bfb0d4660ccaca1c975e
ToppCell	Parenchyma_Control_(B.)-Epithelial-TX-Basal_2\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	CLCA4 WNT7A LAMC2 CSMD3	1.56e-04	198	61	4	686eda427b075e788de38149eae82faf19bd5704
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_basal-Dividing_Basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DSG3 CENPF LAMC2 HMMR	1.56e-04	198	61	4	f088badb90c6c2d916195f5649eda102119c9ac6
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_basal-Suprabasal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CLCA4 DSG3 SCNN1G NOTCH1	1.56e-04	198	61	4	19d8ff3a4f911b13ecc34844202925475ad4d2ab
ToppCell	Non-neuronal-Dividing-IPC-IPC-div1-28\|World / Primary Cells by Cluster	CENPF NUCKS1 CEP152 HMMR	1.59e-04	199	61	4	787688b68ae5d8768c0a24673ae07ab07616764a
ToppCell	Non-neuronal-Dividing-IPC-IPC-div1\|World / Primary Cells by Cluster	CENPF NUCKS1 CEP152 HMMR	1.59e-04	199	61	4	72823f26ecabcae1b514b7629cfce010c97b929a
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	NID2 SCNN1G LAMC2 ATP11A	1.59e-04	199	61	4	d43c605a4ff221cf78d91678c15d2ad20f831c7f
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar-AT_1\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	NID2 SCNN1G LAMC2 ATP11A	1.59e-04	199	61	4	1c70e7d6bd25980e1b92aa1cac3f3c95d9651b4b
ToppCell	Megakaryocytic-erythropoietic-Erythro-cells-Polychromatic_Erythroblast\|Erythro-cells / Lineage, cell class and subclass	CENPF NUCKS1 HMMR METAP2	1.59e-04	199	61	4	304681a6510c05203aab360ed72bfe929d8e4ac3
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_basal-Dividing_Basal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CLCA4 CENPF HMMR LMTK3	1.59e-04	199	61	4	fe22833e69928a1478df265e1c356c463611dedd
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	NID2 SCNN1G LAMC2 ATP11A	1.62e-04	200	61	4	ddfb1f006365bf16203ee49f20200f68220cc288
ToppCell	(5)_Plasma-(5)_Plasmablast\|(5)_Plasma / Spleen cell shreds - cell class (v1) and cell subclass (v1)	CENPF NUCKS1 HMMR NOTCH1	1.62e-04	200	61	4	bba54e9acc7514e123de083a4eb49e7bcdb3dac3
ToppCell	Parenchymal-10x3prime_v2-Epithelial-Epi_alveolar-AT1\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	WNT7A SCNN1G LAMC2 ATP11A	1.62e-04	200	61	4	3d51aebf626dd4656ab4aac8a20d761b8062c42d
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	NID2 SCNN1G LAMC2 ATP11A	1.62e-04	200	61	4	8683445ad5b70748c4a1f12eb77d47623085147e
ToppCell	3'-GW_trimst-2-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CENPF NUCKS1 CEP152 HMMR	1.62e-04	200	61	4	63f9481059be608ddc9fe9c7a8f8503fce9755dd
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CENPF NUCKS1 CEP152 HMMR	1.62e-04	200	61	4	38665128b54f4a81b53c961427aed67bf4e2510b
ToppCell	Bronchial-10x5prime-Epithelial-Epi_airway_basal-Suprabasal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CLCA4 DSG3 LAMC2 LMTK3	1.62e-04	200	61	4	ce969c958a31145bbfe315a9a865d7900ecc9549
ToppCell	Tracheal-10x3prime_v2-Epithelial-Epi_airway_basal-Suprabasal\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	CLCA4 SCNN1G LMTK3 NOTCH1	1.62e-04	200	61	4	d536180a308abc5703d5c8bb33dfe57dc4cc6577
ToppCell	Sigmoid-T_cell-Tfh\|T_cell / Region, Cell class and subclass	SNED1 CFAP54 NOTCH1 PTK2	1.62e-04	200	61	4	dd7dcf25520f065bf0d33d589f3c176f63875dc9
ToppCell	Cerebellum-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Sln_(Unipolar_brush_cell)-\|Cerebellum / BrainAtlas - Mouse McCarroll V32	KCNH6 TCP11 LAMC2	2.73e-04	92	61	3	a5b89f971b904b8e280fe66996a7f8efd92c2132
ToppCell	Cerebellum-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Sln_(Unipolar_brush_cell)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	KCNH6 TCP11 LAMC2	2.73e-04	92	61	3	b867cd7923585b13beaf086c40781bab2d7b7434
ToppCell	LPS_only-Epithelial_alveolar-AT_2-Differentiating_AT1\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LAMC2 ATP11A ACTL6B	7.01e-04	127	61	3	5b0adbcafad31a6759c9bdce2f7f9591a8edc450
ToppCell	droplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FEZ1 HMMR NOTCH1	7.67e-04	131	61	3	419a0a83b38eaea890d065c3f252ef83c2d37b5b
ToppCell	Endothelial-H_(cycle)\|World / shred on cell class and cell subclass (v4)	CENPF NUCKS1 HMMR	8.02e-04	133	61	3	8e3005114761feee028c496cc739e607b35d7831
ToppCell	MS-CD4-CD4_Treg\|MS / Condition, Cell_class and T cell subcluster	KCNH6 TNFRSF4 C16orf46	9.49e-04	141	61	3	df257dd4dcc45c1ace57340798e150a6e932531d
ToppCell	PBMC-Control-Myeloid-Neutrophil-Neutrophil-Neu_1\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FLNC IGF2R CR1L	9.69e-04	142	61	3	191a13bba143ecdfc2bfd797c3ac191481388298
ToppCell	PND01-03-samps-Mesenchymal-Myofibroblast-myofibroblast_-_immature_2\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	KCNH6 BRF1 UMODL1	9.89e-04	143	61	3	abe6ec0f6956b87f394d537926eb2427fcfad93f
Drug	AC1L1G5B	INTU KAT6A DDIT3 PTK2	6.54e-06	46	60	4	CID000003531
Drug	4-toluenesulfonyl fluoride	PNPLA6 LAMC2	6.83e-06	2	60	2	ctd:C003614
Disease	Malignant neoplasm of breast	KLK15 NID2 TGM2 CENPF RNF149 LAMA2 AKT2 HMMR DDIT3 NOTCH1	4.86e-05	1074	59	10	C0006142
Disease	brain measurement, neuroimaging measurement	NEO1 ADAMTS20 LAMC2 GBA2 METAP2 PTK2 TG	1.11e-04	550	59	7	EFO_0004346, EFO_0004464
Disease	Cystic Fibrosis	CLCA4 SCNN1G	2.14e-04	11	59	2	C0010674
Disease	neuroimaging measurement	NEO1 WNT7A LAMA2 NUCKS1 ADAMTS20 METAP2 PTK2 STPG2 TG	2.56e-04	1069	59	9	EFO_0004346
Disease	cortical surface area measurement	INTU NEO1 WNT7A ATAD2B LAMA2 ADAMTS20 ACTL6B METAP2 STPG2 TG	3.06e-04	1345	59	10	EFO_0010736
Disease	cortical thickness	INTU NEO1 UMODL1 WNT7A LAMA2 NUCKS1 ADAMTS20 STPG2 TG	3.45e-04	1113	59	9	EFO_0004840
Disease	Colorectal Carcinoma	TGM2 FLNC BRF1 ZNF155 SCNN1G CSMD3 DDIT3	4.88e-04	702	59	7	C0009402
Disease	ischemia (implicated_via_orthology)	SCNN1G AKT2	5.24e-04	17	59	2	DOID:326 (implicated_via_orthology)
Disease	Glioblastoma	TGM2 NOTCH1 PTK2	5.39e-04	79	59	3	C0017636
Disease	Mammary Carcinoma, Human	TGM2 CENPF AKT2 HMMR DDIT3 NOTCH1	6.25e-04	525	59	6	C4704874
Disease	Mammary Neoplasms, Human	TGM2 CENPF AKT2 HMMR DDIT3 NOTCH1	6.25e-04	525	59	6	C1257931
Disease	alcohol use disorder (implicated_via_orthology)	KCNU1 AKT2 ACTL6B NOTCH1	6.34e-04	195	59	4	DOID:1574 (implicated_via_orthology)
Disease	Mammary Neoplasms	TGM2 CENPF AKT2 HMMR DDIT3 NOTCH1	6.38e-04	527	59	6	C1458155
Disease	Giant Cell Glioblastoma	TGM2 NOTCH1 PTK2	6.45e-04	84	59	3	C0334588
Disease	Breast Carcinoma	TGM2 CENPF AKT2 HMMR DDIT3 NOTCH1	7.10e-04	538	59	6	C0678222
Disease	osteoarthritis, hip, osteoarthritis, knee, total joint arthroplasty	TCP11 BRWD1	8.05e-04	21	59	2	EFO_0004616, EFO_0010726, EFO_1000786
Disease	Seckel syndrome	CENPF CEP152	8.85e-04	22	59	2	C0265202
Disease	lung small cell carcinoma (is_implicated_in)	LAMC2 PTK2	1.44e-03	28	59	2	DOID:5409 (is_implicated_in)
Disease	Glioblastoma Multiforme	TGM2 NOTCH1 PTK2	1.44e-03	111	59	3	C1621958
Disease	lifestyle measurement, alcohol consumption measurement	INTU CFAP54 CSMD2	1.60e-03	115	59	3	EFO_0007878, EFO_0010724
Disease	colorectal cancer (implicated_via_orthology)	BRF1 NOTCH1	1.65e-03	30	59	2	DOID:9256 (implicated_via_orthology)
Disease	Epileptic encephalopathy	ACTL6B ALG13	1.65e-03	30	59	2	C0543888
Disease	Polydactyly	PNPLA6 CENPF WNT7A	1.68e-03	117	59	3	C0152427
Disease	heart conduction disease (implicated_via_orthology)	KCNH6 KCNU1	1.88e-03	32	59	2	DOID:10273 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
YSERPCEGDSPGNET	UMODL1	936	Q5DID0
GEDPMDYKCGSPSDS	AKT2	116	P31751
PIEDKGEFSVPSCYG	CFAP54	1701	Q96N23
DEGGSGYSPPSKCEQ	CEP152	126	O94986
PEGYNKGTEETKSPE	ALG13	431	Q9NP73
YSCDPSGSDLPQDTK	ALG13	966	Q9NP73
STTPKCGHYPEESED	CFAP97	236	Q9P2B7
GYTLSDGEPLECEPN	CSMD2	896	Q7Z408
YKEIEKESCGDPGTP	CSMD3	656	Q7Z407
GYAGEDCPKADFPTT	ACTL6B	26	O94805
NSTDAEPVGDFPCGK	CACNA1B	256	Q00975
PGPEDTGKACGVDYE	ARRB1	131	P49407
GQSASYCDAASKPPE	ADAMTS20	1336	P59510
FTEETEPTYTCPDGK	C16orf46	21	Q6P387
DADEDYGRDSGPPTK	NUCKS1	21	Q9H1E3
QPPSKDSGYGIESCG	DSG3	871	P32926
TTDEPTEPGKYPCGE	FAM47C	171	Q5HY64
IEPPTSYVSDGCADG	PNPLA6	1301	Q8IY17
PSGYTGPACSQDVDE	NOTCH1	401	P46531
KGQECEYPPTQDGRT	METAP2	131	P50579
PCHGPEENEYKSEGT	MAVS	451	Q7Z434
CSNALEYNPDKDPGD	ATAD2B	1031	Q9ULI0
AQTPSYGDLDDCSPK	KCNH6	896	Q9H252
EGEDCSGEYTPPAEE	LMTK3	76	Q96Q04
GDVPCDNTTKPGVYT	KLK15	226	Q9H2R5
CYSVNGDADSEGPPE	MTSS2	496	Q765P7
GFYPCSEIEDPAEKG	PDE3B	406	Q13370
KDGSCTVEYIPFTPG	FLNC	1401	Q14315
GEEEPKSPEEYQCSG	LRRC71	46	Q8N4P6
TGPPSYAKDDEVICT	LAMA2	186	P24043
EDPEEKPQCFYGSSP	FEZ1	21	Q99689
DPVGSCSSYEDKTIP	KCNU1	126	A8MYU2
GSPGPDCVYVDQVKT	INTU	616	Q9ULD6
GCAPSPGAYDVKTLE	HMMR	16	O75330
VKEDSDPTPGNPCYD	NID2	751	Q14112
TSSAPQEQYGECGEK	KAT6A	891	Q92794
YEDKEDLSSNCPGPT	GPATCH11	266	Q8N954
YEPPGEDKTQGSSEC	CENPF	1731	P49454
PQVYCPEETGGTKDV	GBA2	26	Q9HCG7
GEPSIYCTSKDDQVG	CR1L	201	Q2VPA4
PDGSGIYDPCEKEAT	ILF3	286	Q12906
QYACEGKPPDPDSEG	BRWD1	1991	Q9NSI6
PDTGDCYSGDENPDI	LAMC2	426	Q13753
GTYVSPPGNEEEESK	DDIT3	36	P35638
SEPYSQCTEDGSDVP	SCNN1G	366	P51170
SYVNGDRCPPETDDG	IGF2R	1886	P11717
GKQPSGPSEESAEGY	PRDM14	386	Q9GZV8
PEEGISYLTDKGCNP	PTK2	276	Q05397
CVVESGGPPKYSDEV	NEO1	221	Q92859
GYTGEDCAKELFPPT	SNED1	896	Q8TER0
PGRDEPYTKQFTECG	CLCA4	111	Q14CN2
PDGGKSCVYISSSPD	ATP11A	496	P98196
ALDPTPQEKSEGTYC	TGM2	356	P21980
KYPGDSEGRSCKPET	TCP11	11	Q8WWU5
ESEPQCDPSFKGDAG	RNF149	366	Q8NC42
SVQKEACATPGPADY	STPG2	296	Q8N412
EEECDPPSYTAGQRK	BRF1	286	Q92994
AGTQPLDSYKPGVDC	TNFRSF4	111	P43489
IEKSPNYCEEDPVTG	WNT7A	271	O00755
DQPRDYSGENPSKCE	ZNF155	501	Q12901
TKYDEATGLCPEGDE	UNK	91	Q9C0B0
KCPEGSYSQDEECIP	TG	1461	P01266