Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	microtubule-based movement	ADCY10 DRC7 CACNA1E KIFBP CFAP54 MAK SYNE2 BBS2 RABGEF1 DNAH8	1.63e-05	493	78	10	GO:0007018
GeneOntologyBiologicalProcess	microtubule-based process	ADCY10 DRC7 TBC1D32 CACNA1E KIFBP CFAP54 MAK SYNE2 PRKAA2 CLTC DYRK1A BBS2 RABGEF1 DNAH8	3.79e-05	1058	78	14	GO:0007017
Domain	TPR-like_helical_dom	ADCY10 KIFBP CFAP54 CLTC STIP1 PRKDC ANAPC7 IFIT3	5.75e-06	233	78	8	IPR011990
Domain	-	ADCY10 KIFBP CFAP54 CLTC STIP1 ANAPC7 IFIT3	2.52e-05	207	78	7	1.25.40.10
Domain	Ser/Thr_kinase_SIK1/2	SIK2 SIK1	5.15e-05	3	78	2	IPR017090
Domain	ARM-type_fold	DOCK3 PDS5B IPO7 CLTC PDS5A PRKDC XPOT	5.34e-04	339	78	7	IPR016024
Domain	TPR_2	STIP1 ANAPC7 IFIT3	1.19e-03	50	78	3	PF07719
Domain	TPR_2	STIP1 ANAPC7 IFIT3	1.19e-03	50	78	3	IPR013105
Domain	TPR_8	STIP1 ANAPC7 IFIT3	1.41e-03	53	78	3	PF13181
Domain	IBN_N	IPO7 XPOT	1.75e-03	15	78	2	PF03810
Domain	Kinase-like_dom	MAK BTK PRKAA2 DYRK1A SIK2 SIK1 PRKDC RIOK2	1.89e-03	542	78	8	IPR011009
Domain	IBN_N	IPO7 XPOT	1.99e-03	16	78	2	SM00913
Domain	Disintegrin_CS	ADAM19 ADAM28	1.99e-03	16	78	2	IPR018358
Domain	Importin-beta_N	IPO7 XPOT	2.25e-03	17	78	2	IPR001494
Domain	-	PDS5B IPO7 PDS5A PRKDC XPOT	2.37e-03	222	78	5	1.25.10.10
Domain	ADAM_CR	ADAM19 ADAM28	2.52e-03	18	78	2	PF08516
Domain	Ca/CaM-dep_Ca-dep_prot_Kinase	PRKAA2 SIK2 SIK1	3.01e-03	69	78	3	IPR020636
Domain	-	ADAM19 ADAM28	3.12e-03	20	78	2	4.10.70.10
Domain	HEAT_REPEAT	PDS5B PDS5A PRKDC	3.14e-03	70	78	3	PS50077
Domain	-	PMS1 LONP2	3.43e-03	21	78	2	3.30.230.10
Domain	Disintegrin	ADAM19 ADAM28	3.43e-03	21	78	2	PF00200
Domain	DISIN	ADAM19 ADAM28	3.43e-03	21	78	2	SM00050
Domain	-	MYCBP2 LAMA2 SUCO	3.53e-03	73	78	3	2.60.120.260
Domain	TPR-contain_dom	STIP1 PRKDC ANAPC7 IFIT3	3.60e-03	150	78	4	IPR013026
Domain	Ribosomal_S5_D2-typ_fold_subgr	PMS1 LONP2	3.77e-03	22	78	2	IPR014721
Domain	Prot_kinase_dom	MAK BTK PRKAA2 DYRK1A SIK2 SIK1 RIOK2	4.31e-03	489	78	7	IPR000719
Domain	PROTEIN_KINASE_DOM	MAK BTK PRKAA2 DYRK1A SIK2 SIK1 RIOK2	4.50e-03	493	78	7	PS50011
Domain	TPR_REGION	STIP1 PRKDC ANAPC7 IFIT3	5.04e-03	165	78	4	PS50293
Domain	TPR	STIP1 PRKDC ANAPC7 IFIT3	5.04e-03	165	78	4	PS50005
Domain	Protein_kinase_ATP_BS	MAK BTK PRKAA2 DYRK1A SIK2 SIK1	5.05e-03	379	78	6	IPR017441
Domain	ARM-like	PDS5B IPO7 PDS5A PRKDC XPOT	5.45e-03	270	78	5	IPR011989
Domain	ACR	ADAM19 ADAM28	5.65e-03	27	78	2	SM00608
Domain	ADAM_Cys-rich	ADAM19 ADAM28	5.65e-03	27	78	2	IPR006586
Domain	Galactose-bd-like	MYCBP2 LAMA2 SUCO	7.15e-03	94	78	3	IPR008979
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	PDS5B KIFBP CYFIP1 IPO7 ABCE1 VPS13C PRKAA2 SMC6 CLTC SUPT16H PDS5A STIP1 SMARCAD1 PRKDC ANAPC7 XPOT	9.06e-08	1425	78	16	30948266
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	CYFIP1 HAGHL ABCE1 BTK PRKAA2 SUPT16H SCAPER DYRK1A SIK2 SAV1 SIK1 RIOK2 ANAPC7	1.14e-07	910	78	13	36736316
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	TBC1D32 KIFBP MAK CYFIP1 MYCBP2 LONP2 SMC6 SUPT16H DYRK1A SAV1 BBS2 RABGEF1 ANAPC7 TRAPPC1 ARID3B	2.11e-07	1321	78	15	27173435
Pubmed	The LKB1-salt-inducible kinase pathway functions as a key gluconeogenic suppressor in the liver.	PRKAA2 SIK2 SIK1	3.77e-07	7	78	3	25088745
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	ADK PDS5B IPO7 ABCE1 SMC6 SUPT16H PDS5A SMARCAD1 PRKDC MED13L ANAPC7 TFAP2A MAGEC2	3.89e-07	1014	78	13	32416067
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	PMS1 KIFBP IPO7 MYCBP2 SYNE2 CLTC SUPT16H SIK2 BBS2 SMPD4 STIP1 SMARCAD1 MMAB SUCO NOL8	9.39e-07	1487	78	15	33957083
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	TPM2 SF3B4 CYFIP1 IPO7 MYCBP2 SYNE2 CLTC PDS5A STIP1 SMARCAD1 PRKDC MMAB RIOK2 XPOT	1.03e-06	1297	78	14	33545068
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	PMS1 PDS5B IPO7 SMC6 SUPT16H PDS5A SMARCAD1 ANAPC7 TFAP2A ARID3B	1.07e-06	608	78	10	36089195
Pubmed	Scc1 sumoylation by Mms21 promotes sister chromatid recombination through counteracting Wapl.	PDS5B SMC6 PDS5A	1.29e-06	10	78	3	22751501
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	PMS1 PDS5B SF3B4 CYFIP1 SMC6 CLTC SUPT16H PDS5A PRKDC TFAP2A NOL8 ARID3B	1.39e-06	954	78	12	36373674
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	TPM2 IPO7 MYCBP2 SYNE2 CLTC SUPT16H LAMA2 RABGEF1 STIP1	1.76e-06	497	78	9	23414517
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	PDS5B KIFBP CYFIP1 ABCE1 CLTC SUPT16H PDS5A SMARCAD1 PRKDC DNAH8	3.95e-06	704	78	10	29955894
Pubmed	Limited role of antibody in clearance of Streptococcus pneumoniae in a murine model of colonization.	BTK PRKDC	4.97e-06	2	78	2	15385481
Pubmed	PDS5A and PDS5B differentially affect gene expression without altering cohesin localization across the genome.	PDS5B PDS5A	4.97e-06	2	78	2	35986423
Pubmed	PDS5 proteins are required for proper cohesin dynamics and participate in replication fork protection.	PDS5B PDS5A	4.97e-06	2	78	2	31757807
Pubmed	LKB1 tumor suppressor and salt-inducible kinases negatively regulate human T-cell leukemia virus type 1 transcription.	SIK2 SIK1	4.97e-06	2	78	2	23577667
Pubmed	PDS5A and PDS5B in Cohesin Function and Human Disease.	PDS5B PDS5A	4.97e-06	2	78	2	34070827
Pubmed	Expression of Mls determinants in mice exhibiting the severe combined immunodeficiency (scid) mutation or X-linked immunodeficiency (xid) defect.	BTK PRKDC	4.97e-06	2	78	2	1506683
Pubmed	Antagonistic modulation of SIK1 and SIK2 isoforms in high blood pressure and cardiac hypertrophy triggered by high-salt intake.	SIK2 SIK1	4.97e-06	2	78	2	33688765
Pubmed	Loss of the conserved PKA sites of SIK1 and SIK2 increases sleep need.	SIK2 SIK1	4.97e-06	2	78	2	32457359
Pubmed	Activation of AMP-activated protein kinase α2 by nicotine instigates formation of abdominal aortic aneurysms in mice in vivo.	PRKAA2 TFAP2A	4.97e-06	2	78	2	22561688
Pubmed	Ability of spleen, peritoneal cavity, and lymph node B cells to reconstitute serum immunoglobulin in SCID mice.	BTK PRKDC	4.97e-06	2	78	2	8707345
Pubmed	Double mutations in klotho and osteoprotegerin gene loci rescued osteopetrotic phenotype.	KL TNFRSF11B	4.97e-06	2	78	2	12446599
Pubmed	Novel mutations in TPM2 and PIEZO2 are responsible for distal arthrogryposis (DA) 2B and mild DA in two Chinese families.	TPM2 PIEZO2	4.97e-06	2	78	2	30285720
Pubmed	Recognition sites for clathrin-associated proteins AP-2 and AP-3 on clathrin triskelia.	CLTC TFAP2A	4.97e-06	2	78	2	1587861
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	DOCK3 SF3B4 ADAM19 MYCBP2 MICAL2 CLTC DYRK1A SMARCAD1 PRKDC MED13L TERF1 TRAPPC1 XPOT	5.32e-06	1285	78	13	35914814
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	PDS5B IPO7 MYCBP2 ABCE1 CLTC PDS5A PRKDC MED13L ANAPC7 TFAP2A XPOT ARID3B	6.16e-06	1103	78	12	34189442
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	PMS1 SF3B4 IPO7 VPS13C JRK SYNE2 SMC6 BBS2 SMPD4 ANAPC7	7.21e-06	754	78	10	35906200
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	PDS5B CYFIP1 IPO7 MYCBP2 ABCE1 MICAL2 CLTC SUPT16H PDS5A SMARCAD1 PRKDC RIOK2 XPOT	9.25e-06	1353	78	13	29467282
Pubmed	Expression analysis of the entire MMP and TIMP gene families during mouse tissue development.	ADAM19 TIMP1 ADAM28	1.02e-05	19	78	3	15063736
Pubmed	DDX39B facilitates the malignant progression of hepatocellular carcinoma via activation of SREBP1-mediated de novo lipid synthesis.	IPO7 CLTC SUPT16H PRKDC	1.26e-05	63	78	4	37052853
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	SF3B4 CYFIP1 IPO7 CLTC SUPT16H PDS5A STIP1 PRKDC XPOT	1.32e-05	638	78	9	33239621
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	PDS5B SF3B4 CYFIP1 IPO7 MICAL2 SMC6 CLTC DYRK1A SMPD4 PDS5A PRKDC XPOT	1.47e-05	1203	78	12	29180619
Pubmed	Inhibition of SIK2 and SIK3 during differentiation enhances the anti-inflammatory phenotype of macrophages.	SIK2 SIK1	1.49e-05	3	78	2	27920213
Pubmed	Salt-inducible kinase 3 deficiency exacerbates lipopolysaccharide-induced endotoxin shock accompanied by increased levels of pro-inflammatory molecules in mice.	SIK2 SIK1	1.49e-05	3	78	2	25619259
Pubmed	Pds5B is required for cohesion establishment and Aurora B accumulation at centromeres.	PDS5B PDS5A	1.49e-05	3	78	2	24141881
Pubmed	DNA-PK Promotes the Mitochondrial, Metabolic, and Physical Decline that Occurs During Aging.	PRKAA2 PRKDC	1.49e-05	3	78	2	28467930
Pubmed	Effect of clathrin heavy chain- and alpha-adaptin-specific small inhibitory RNAs on endocytic accessory proteins and receptor trafficking in HeLa cells.	CLTC TFAP2A	1.49e-05	3	78	2	12960147
Pubmed	Salt-inducible kinase-1 represses cAMP response element-binding protein activity both in the nucleus and in the cytoplasm.	SIK2 SIK1	1.49e-05	3	78	2	15511237
Pubmed	The inositol polyphosphate 5-phosphatase Ocrl associates with endosomes that are partially coated with clathrin.	CLTC TFAP2A	1.49e-05	3	78	2	15353600
Pubmed	Pravastatin activates activator protein 2 alpha to augment the angiotensin II-induced abdominal aortic aneurysms.	PRKAA2 TFAP2A	1.49e-05	3	78	2	28179583
Pubmed	Pds5 Regulates Sister-Chromatid Cohesion and Chromosome Bi-orientation through a Conserved Protein Interaction Module.	PDS5B PDS5A	1.49e-05	3	78	2	28343969
Pubmed	Bruton's tyrosine kinase inhibition effectively protects against human IgE-mediated anaphylaxis.	BTK PRKDC	1.49e-05	3	78	2	32484802
Pubmed	Salt-Inducible Kinase 1 Terminates cAMP Signaling by an Evolutionarily Conserved Negative-Feedback Loop in β-Cells.	SIK2 SIK1	1.49e-05	3	78	2	25918234
Pubmed	Huntingtin interacting protein 1 Is a clathrin coat binding protein required for differentiation of late spermatogenic progenitors.	CLTC TFAP2A	1.49e-05	3	78	2	11604514
Pubmed	Salt-inducible Kinases Are Critical Determinants of Female Fertility.	SIK2 SIK1	1.49e-05	3	78	2	32343771
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	SF3B4 CYFIP1 IPO7 LONP2 SYNE2 CLTC SUPT16H PDS5A STIP1 SMARCAD1 PRKDC RIOK2 XPOT	1.49e-05	1415	78	13	28515276
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	PDS5B IPO7 MYCBP2 ABCE1 SYNE2 CLTC PDS5A PRKDC XPOT	1.58e-05	653	78	9	22586326
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	TPM2 KIFBP IPO7 SYNE2 CLTC SUPT16H SMPD4 PDS5A STIP1 PRKDC IFIT3 TRAPPC1 XPOT	1.79e-05	1440	78	13	30833792
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	TPM2 TBC1D32 KIFBP DYRK1A SMPD4 PDS5A SMARCAD1 ANAPC7 TFAP2A ARID3B	2.17e-05	857	78	10	25609649
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	PMS1 SF3B4 IPO7 MYCBP2 SYNE2 CLTC SUPT16H SMPD4 STIP1 TFAP2A XPOT	2.19e-05	1049	78	11	27880917
Pubmed	Myosin VI isoform localized to clathrin-coated vesicles with a role in clathrin-mediated endocytosis.	CLTC TFAP2A	2.97e-05	4	78	2	11447109
Pubmed	Mutant GNAS drives pancreatic tumourigenesis by inducing PKA-mediated SIK suppression and reprogramming lipid metabolism.	SIK2 SIK1	2.97e-05	4	78	2	29941929
Pubmed	Eps15 mediates vesicle trafficking from the trans-Golgi network via an interaction with the clathrin adaptor AP-1.	CLTC TFAP2A	2.97e-05	4	78	2	18524853
Pubmed	Pre-B-cell leukemias in Btk/Slp65-deficient mice arise independently of ongoing V(D)J recombination activity.	BTK PRKDC	2.97e-05	4	78	2	21030983
Pubmed	B1 B lymphocytes play a critical role in host protection against lymphatic filarial parasites.	BTK PRKDC	2.97e-05	4	78	2	10684864
Pubmed	Strain-dependent leakiness of mice with severe combined immune deficiency.	BTK PRKDC	2.97e-05	4	78	2	8473734
Pubmed	Regulation of vascular calcification by osteoclast regulatory factors RANKL and osteoprotegerin.	KL TNFRSF11B	2.97e-05	4	78	2	15564564
Pubmed	Importance of autophosphorylation at Ser186 in the A-loop of salt inducible kinase 1 for its sustained kinase activity.	SIK2 SIK1	2.97e-05	4	78	2	18348280
Pubmed	Topologically associating domains and chromatin loops depend on cohesin and are regulated by CTCF, WAPL, and PDS5 proteins.	PDS5B PDS5A	2.97e-05	4	78	2	29217591
Pubmed	Use of differential display analysis to assess the effect of human cytomegalovirus infection on the accumulation of cellular RNAs: induction of interferon-responsive RNAs.	RSAD2 IFIT3	2.97e-05	4	78	2	9391139
Pubmed	Silencing the constitutive active transcription factor CREB by the LKB1-SIK signaling cascade.	SIK2 SIK1	2.97e-05	4	78	2	16817901
Pubmed	Dyrk1A binds to multiple endocytic proteins required for formation of clathrin-coated vesicles.	CLTC DYRK1A	2.97e-05	4	78	2	19722700
Pubmed	The LKB1-SIK Pathway Controls Dendrite Self-Avoidance in Purkinje Cells.	SIK2 SIK1	2.97e-05	4	78	2	30208308
Pubmed	Adipose-specific expression, phosphorylation of Ser794 in insulin receptor substrate-1, and activation in diabetic animals of salt-inducible kinase-2.	SIK2 SIK1	2.97e-05	4	78	2	12624099
Pubmed	Sympathetic inputs regulate adaptive thermogenesis in brown adipose tissue through cAMP-Salt inducible kinase axis.	SIK2 SIK1	2.97e-05	4	78	2	30030465
Pubmed	PDS5 proteins regulate the length of axial elements and telomere integrity during male mouse meiosis.	PDS5B PDS5A	2.97e-05	4	78	2	32285610
Pubmed	Effect of immunodeficiency on diabetogenesis in genetically diabetic (db/db) mice.	BTK PRKDC	2.97e-05	4	78	2	3553324
Pubmed	Serum levels of the osteoprotegerin, receptor activator of nuclear factor kappa-B ligand, metalloproteinase-1 (MMP-1) and tissue inhibitors of MMP-1 levels are increased in men 6 months after acute myocardial infarction.	TIMP1 TNFRSF11B	2.97e-05	4	78	2	18298349
Pubmed	Elevated serum receptor activator of NFkappaB ligand (RANKL), osteoprotegerin (OPG), matrix metalloproteinase (MMP)3, and ProMMP1 in patients with juvenile idiopathic arthritis.	TIMP1 TNFRSF11B	2.97e-05	4	78	2	17703334
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	KIFBP IPO7 SYNE2 DYRK1A STIP1 PRKDC ARID3B	3.20e-05	398	78	7	35016035
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	PDS5B CYFIP1 IPO7 CLTC PDS5A ANAPC7 XPOT ARID3B	3.75e-05	560	78	8	35241646
Pubmed	Cellular substrates and pro-apoptotic function of the human HtrA4 protease.	ADK SF3B4 IPO7 CLTC DYRK1A	4.52e-05	173	78	5	31470122
Pubmed	STK11 is required for the normal program of ciliated cell differentiation in airways.	PRKAA2 SIK2 SIK1	4.66e-05	31	78	3	31636950
Pubmed	CCT3 acts upstream of YAP and TFCP2 as a potential target and tumour biomarker in liver cancer.	TPM2 IPO7 CLTC STIP1 PRKDC ARID3B	4.77e-05	288	78	6	31501420
Pubmed	RioK1, a new interactor of protein arginine methyltransferase 5 (PRMT5), competes with pICln for binding and modulates PRMT5 complex composition and substrate specificity.	SF3B4 IPO7 CLTC SUPT16H PRKDC IFIT3 XPOT	4.85e-05	425	78	7	21081503
Pubmed	Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication.	PRKDC TERF1	4.94e-05	5	78	2	19596237
Pubmed	The resolution of relapsing fever borreliosis requires IgM and is concurrent with expansion of B1b lymphocytes.	BTK PRKDC	4.94e-05	5	78	2	12646649
Pubmed	Phosphorylation of CRTC3 by the salt-inducible kinases controls the interconversion of classically activated and regulatory macrophages.	SIK2 SIK1	4.94e-05	5	78	2	23033494
Pubmed	Deficiency of insulin-like growth factor 1 reduces sensitivity to aging-associated cardiomyocyte dysfunction.	KL PRKAA2	4.94e-05	5	78	2	18729805
Pubmed	A parathyroid hormone/salt-inducible kinase signaling axis controls renal vitamin D activation and organismal calcium homeostasis.	SIK2 SIK1	4.94e-05	5	78	2	36862513
Pubmed	ARH is a modular adaptor protein that interacts with the LDL receptor, clathrin, and AP-2.	CLTC TFAP2A	4.94e-05	5	78	2	12221107
Pubmed	Salt inducible kinases 2 and 3 are required for thymic T cell development.	SIK2 SIK1	4.94e-05	5	78	2	34732767
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	PDS5B MYCBP2 SMC6 SUPT16H SCAPER PRKDC TERF1 NOL8 ARID3B	5.10e-05	759	78	9	35915203
Pubmed	Scanning the human proteome for calmodulin-binding proteins.	DOCK3 MYCBP2 SYNE2 SCAPER	5.63e-05	92	78	4	15840729
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	CACNA1E KIFBP CYFIP1 MYCBP2 SYNE2 CLTC SUPT16H DYRK1A RABGEF1 STIP1	5.80e-05	963	78	10	28671696
Pubmed	14-3-3 proteins mediate inhibitory effects of cAMP on salt-inducible kinases (SIKs).	SIK2 SIK1	7.40e-05	6	78	2	29211348
Pubmed	Salt-inducible kinases are required for the IL-33-dependent secretion of cytokines and chemokines in mast cells.	SIK2 SIK1	7.40e-05	6	78	2	33600797
Pubmed	Dual targeting of salt inducible kinases and CSF1R uncouples bone formation and bone resorption.	SIK2 SIK1	7.40e-05	6	78	2	34160349
Pubmed	SIK inhibition in human myeloid cells modulates TLR and IL-1R signaling and induces an anti-inflammatory phenotype.	SIK2 SIK1	7.40e-05	6	78	2	26590148
Pubmed	Isolation and characterization of novel presenilin binding protein.	DOCK3 KCNIP3	7.40e-05	6	78	2	10854253
Pubmed	Sororin, a substrate of the anaphase-promoting complex, is required for sister chromatid cohesion in vertebrates.	PDS5B PDS5A	7.40e-05	6	78	2	15837422
Pubmed	Nasopharyngeal Exposure to Streptococcus pneumoniae Induces Extended Age-Dependent Protection against Pulmonary Infection Mediated by Antibodies and CD138+ Cells.	BTK PRKDC	7.40e-05	6	78	2	29661828
Pubmed	Phosphoinositide 3-kinase regulates beta2-adrenergic receptor endocytosis by AP-2 recruitment to the receptor/beta-arrestin complex.	CLTC TFAP2A	7.40e-05	6	78	2	12163475
Pubmed	Genomic analysis of mouse retinal development.	FANCC TPM2 MAK SMC6 SUPT16H BBS2 RABGEF1 PRKDC RIOK2 TRAPPC1	8.32e-05	1006	78	10	15226823
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	TBC1D32 CYFIP1 IPO7 ABCE1 SYNE2 ARHGAP45 TFAP2A ARID3B	9.31e-05	638	78	8	31182584
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	PDS5B IPO7 MYCBP2 SYNE2 CLTC SUPT16H STIP1 PRKDC MMAB ANAPC7	9.63e-05	1024	78	10	24711643
Pubmed	DNA-dependent protein kinase regulates lysosomal AMP-dependent protein kinase activation and autophagy.	PRKAA2 PRKDC	1.04e-04	7	78	2	31983282
Pubmed	Functional contribution of Pds5 to cohesin-mediated cohesion in human cells and Xenopus egg extracts.	PDS5B PDS5A	1.04e-04	7	78	2	15855230
Pubmed	Dosage effects of cohesin regulatory factor PDS5 on mammalian development: implications for cohesinopathies.	PDS5B PDS5A	1.04e-04	7	78	2	19412548
Interaction	CIAO1 interactions	RSAD2 MYCBP2 ABCE1 MICAL2 VPS13C CLTC SUPT16H SMPD4	1.60e-05	289	78	8	int:CIAO1
Interaction	H3C3 interactions	PMS1 PDS5B IPO7 SMC6 SUPT16H PDS5A SMARCAD1 ANAPC7 TFAP2A ARID3B	2.06e-05	495	78	10	int:H3C3
Interaction	ADAM23 interactions	ADAM19 DYRK1A ADAM28	3.01e-05	16	78	3	int:ADAM23
Interaction	ANAPC2 interactions	ABCE1 DYRK1A SMPD4 STIP1 SMARCAD1 PRKDC ANAPC7	3.41e-05	234	78	7	int:ANAPC2
Cytoband	6p24	MAK TFAP2A	1.71e-05	4	78	2	6p24
Cytoband	1q24	ADCY10 SUCO	5.31e-04	20	78	2	1q24
Cytoband	15q24	SCAPER ARID3B	5.86e-04	21	78	2	15q24
Cytoband	12q24.11	FAM216A ANAPC7	1.45e-03	33	78	2	12q24.11
Cytoband	16q21	DRC7 BBS2	2.69e-03	45	78	2	16q21
Cytoband	2q21.1	SMPD4 KCNIP3	4.43e-03	58	78	2	2q21.1
GeneFamily	Tetratricopeptide repeat domain containing\|Bardet-Biedl syndrome associated\|BBSome	KIFBP STIP1 ANAPC7 IFIT3	1.44e-04	115	42	4	769
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	ADAM19 ADAM28	1.78e-03	27	42	2	47
Coexpression	RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP	PMS1 ADK MICAL2 SMC6 SUPT16H STIP1 RIOK2 TFAP2A IFIT3 MAGEC2 NOL8 XPOT	1.41e-06	721	78	12	M10237
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	PMS1 PDS5B IPO7 MYCBP2 ABCE1 MICAL2 SYNE2 DYRK1A PDS5A MED13L TERF1 SUCO	8.18e-06	856	78	12	M4500
Coexpression	ABRAMSON_INTERACT_WITH_AIRE	IPO7 SUPT16H PRKDC XPOT	9.00e-06	44	78	4	M2536
Coexpression	GSE411_100MIN_VS_400MIN_IL6_STIM_MACROPHAGE_DN	ADK IPO7 ABCE1 RIOK2 NOL8 XPOT	2.98e-05	200	78	6	M5998
Coexpression	TRAVAGLINI_LUNG_B_CELL	ADK ADAM19 MYCBP2 SMC6 ADAM28	1.01e-04	155	78	5	M41680
Coexpression	FIRESTEIN_PROLIFERATION	ADK MAK BTK SIK1 PRKDC	1.39e-04	166	78	5	M5354
Coexpression	HAMAI_APOPTOSIS_VIA_TRAIL_UP	PDS5B PIEZO2 MYCBP2 VPS13C SYNE2 SMC6 SMARCAD1 RIOK2 SUCO	1.43e-04	656	78	9	M18979
Coexpression	GSE25677_MPL_VS_R848_STIM_BCELL_UP	CACNA1E CYFIP1 MYCBP2 PRKDC SUCO	1.74e-04	174	78	5	M8186
Coexpression	KOINUMA_TARGETS_OF_SMAD2_OR_SMAD3	ADK ADAM19 VPS13C SYNE2 CLTC SAV1 SMPD4 SDR16C5 TFAP2A ARID3B	1.96e-04	843	78	10	M2356
Coexpression	HOEBEKE_LYMPHOID_STEM_CELL_UP	BTK MED13L ARHGAP45 ADAM28	2.04e-04	97	78	4	M14698
Coexpression	DIAZ_CHRONIC_MYELOGENOUS_LEUKEMIA_UP	PMS1 ADK SF3B4 IPO7 TIMP1 ABCE1 BTK SUPT16H DYRK1A SAV1 PRKDC TERF1 XPOT	2.32e-04	1399	78	13	M535
Coexpression	SCHLOSSER_SERUM_RESPONSE_DN	FANCC ADK PDS5B RSAD2 ADAM19 MYCBP2 DYRK1A TERF1 TFAP2A	2.44e-04	705	78	9	M1410
Coexpression	GSE37416_CTRL_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_UP	VPS13C JRK SYNE2 ANAPC7 IFIT3	3.01e-04	196	78	5	M5337
Coexpression	GSE10325_LUPUS_CD4_TCELL_VS_LUPUS_BCELL_DN	ADK BTK SMC6 SIK1 ADAM28	3.01e-04	196	78	5	M3085
Coexpression	GSE3982_CTRL_VS_PMA_STIM_EOSINOPHIL_UP	KL CYFIP1 PRKAA2 PRKDC IFIT3	3.09e-04	197	78	5	M5363
Coexpression	CAO_BLOOD_FLUMIST_AGE_05_14YO_CORRELATED_WITH_H3N2_VN_TITER_7DY_POSITIVE	RSAD2 IFIT3	3.10e-04	9	78	2	M41098
Coexpression	GSE12845_NAIVE_VS_DARKZONE_GC_TONSIL_BCELL_UP	TIMP1 MYCBP2 VPS13C JRK MED13L	3.16e-04	198	78	5	M3200
Coexpression	GSE22935_WT_VS_MYD88_KO_MACROPHAGE_48H_MBOVIS_BCG_STIM_UP	TPM2 AOX1 DYRK1A LAMA2 TNFRSF11B	3.23e-04	199	78	5	M7766
Coexpression	GSE40685_TREG_VS_FOXP3_KO_TREG_PRECURSOR_UP	DPYS RSAD2 VPS13C SIK1 IFIT3	3.23e-04	199	78	5	M9306
Coexpression	GSE24574_BCL6_HIGH_VS_LOW_TFH_CD4_TCELL_UP	TPM2 SYNE2 SIK1 TERF1 ARHGAP45	3.23e-04	199	78	5	M8324
Coexpression	GSE15330_HSC_VS_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_IKAROS_KO_DN	ADAM19 LONP2 VPS13C SUCO TRAPPC1	3.23e-04	199	78	5	M7017
Coexpression	BORCZUK_MALIGNANT_MESOTHELIOMA_UP	KIFBP IPO7 STIP1 PRKDC TERF1 XPOT	3.28e-04	310	78	6	M10236
Coexpression	GSE22886_NAIVE_CD4_TCELL_VS_12H_ACT_TH2_DN	KIFBP SF3B4 CYFIP1 MICAL2 CLTC	3.31e-04	200	78	5	M4527
Coexpression	GSE23114_WT_VS_SLE2C1_MOUSE_SPLEEN_B1A_BCELL_UP	RSAD2 ADAM19 IPO7 ABCE1 TERF1	3.31e-04	200	78	5	M8290
Coexpression	GSE14699_NAIVE_VS_DELETIONAL_TOLERANCE_CD8_TCELL_DN	RSAD2 ADAM19 DNAH8 IFIT3 ARID3B	3.31e-04	200	78	5	M2936
Coexpression	GSE23505_UNTREATED_VS_4DAY_IL6_IL1_TGFB_TREATED_CD4_TCELL_DN	TBC1D32 RSAD2 MYCBP2 HAGHL ARHGAP45	3.31e-04	200	78	5	M7868
Coexpression	GSE27786_LIN_NEG_VS_ERYTHROBLAST_DN	GSTA5 SYNE2 PRKAA2 LAMA2 TNFRSF11B	3.31e-04	200	78	5	M4793
Coexpression	GSE22432_PDC_VS_TGFB1_TREATEDCOMMON_DC_PROGENITOR_DN	BTK SMC6 BBS2 DNAH8 IFIT3	3.31e-04	200	78	5	M7833
Coexpression	GSE19888_ADENOSINE_A3R_INH_PRETREAT_AND_ACT_BY_A3R_VS_TCELL_MEMBRANES_ACT_MAST_CELL_UP	RSAD2 TIMP1 BTK CCDC160 IFIT3	3.31e-04	200	78	5	M7320
Coexpression	GSE23568_CTRL_VS_ID3_TRANSDUCED_CD8_TCELL_UP	MYCBP2 RGS11 STIP1 ARHGAP45 ARID3B	3.31e-04	200	78	5	M8514
Coexpression	GSE46606_IRF4MID_VS_WT_CD40L_IL2_IL5_DAY3_STIMULATED_BCELL_UP	FANCC DOCK3 TCP11 STIP1 MED13L	3.31e-04	200	78	5	M9856
Coexpression	GSE17721_POLYIC_VS_CPG_2H_BMDC_DN	TCP11 SMPD4 STIP1 SUCO TNFRSF11B	3.31e-04	200	78	5	M3939
Coexpression	GSE2128_C57BL6_VS_NOD_CD4CD8_DP_THYMOCYTE_DN	RSAD2 SAV1 SUCO DNAH8 XPOT	3.31e-04	200	78	5	M6184
Coexpression	GSE2770_IL4_ACT_VS_ACT_CD4_TCELL_48H_DN	TBC1D32 RSAD2 CYFIP1 SMPD4 SUCO	3.31e-04	200	78	5	M6042
Coexpression	GSE20715_0H_VS_24H_OZONE_TLR4_KO_LUNG_DN	TIMP1 DYRK1A LAMA2 FAM216A RIOK2	3.31e-04	200	78	5	M4375
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500_k-means-cluster#3	SYNE2 SMC6 SUPT16H PDS5A STIP1 PRKDC NOL8	6.24e-06	192	77	7	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500_K3
CoexpressionAtlas	dev gonad_e13.5_M_GermCell_Oct_top-relative-expression-ranked_500	PMS1 DOCK3 SCAPER MCMDC2 PRKDC TERF1 NOL8 XPOT ARID3B	1.31e-05	396	77	9	gudmap_dev gonad_e13.5_M_GermCell_Oct_500
CoexpressionAtlas	dev gonad_e12.5_F_GermCellOvary_Oct_top-relative-expression-ranked_1000	PMS1 DOCK3 ADAM19 SUPT16H SCAPER STIP1 PRKDC TERF1 DNAH8 NOL8 XPOT ARID3B	3.80e-05	822	77	12	gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_1000
CoexpressionAtlas	dev gonad_e13.5_M_GermCell_Oct_k-means-cluster#1_top-relative-expression-ranked_500	DOCK3 SCAPER MCMDC2 PRKDC	1.16e-04	69	77	4	gudmap_dev gonad_e13.5_M_GermCell_Oct_k1_500
CoexpressionAtlas	FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#3	IPO7 VPS13C SMC6 SUPT16H PDS5A STIP1 SMARCAD1 PRKDC NOL8	1.29e-04	532	77	9	Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_2500_K3
CoexpressionAtlas	dev gonad_e13.5_M_GermCell_Oct_top-relative-expression-ranked_1000	PMS1 DOCK3 TBC1D32 SCAPER MCMDC2 STIP1 PRKDC TERF1 NOL8 XPOT ARID3B	1.56e-04	810	77	11	gudmap_dev gonad_e13.5_M_GermCell_Oct_1000
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	ADK MAK BTK SMC6 SAV1 ADAM28	6.05e-07	173	78	6	d56e337eae727a29cd53cfd628e1b3c0a98e1f51
ToppCell	B_cells-ISG-high_B_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	RSAD2 ADAM19 BTK SMC6 DNAH8 IFIT3	8.40e-07	183	78	6	dc2b00e920efa1dcc2a6265cd1024e3249c9974f
ToppCell	normal-na-Lymphocytic_B-B_naive-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	ADK ADAM19 BTK SMC6 SAV1 ADAM28	9.83e-07	188	78	6	ec72ba73b10c6f2ff39699b6b46b90a3e95a4c24
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ADK ADAM19 BTK SMC6 SAV1 ADAM28	1.05e-06	190	78	6	112706d64ee73b55dcf76f33ca064ab1fc6ce87f
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_B\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ADK ADAM19 BTK SMC6 SAV1 ADAM28	1.08e-06	191	78	6	a831e30f37aff329d83fac9bdb84f783075d5df6
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_B-B_cell\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ADK ADAM19 BTK SMC6 SAV1 ADAM28	1.08e-06	191	78	6	2453064c39b359088d43d52792bf829f83442c82
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_B-B_cell-B_c03-CD27-AIM2\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ADAM19 BTK SMC6 SDR16C5 DNAH8 ADAM28	1.11e-06	192	78	6	e33579a20ca86dcaf02c97273681ba5eee7561b8
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.4.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TPM2 PIEZO2 TIMP1 LAMA2 FAM216A TNFRSF11B	1.15e-06	193	78	6	5bee7abc550ddaa28cbb3b9ecaf6b924ab175de0
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_B-B_cell-B_c03-CD27-AIM2\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ADAM19 BTK SMC6 SDR16C5 DNAH8 ADAM28	1.15e-06	193	78	6	de0213f2105b814f38ffbfd004ea7603230eed68
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_B-B_mem-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ADK ADAM19 SMC6 SDR16C5 DNAH8 ADAM28	1.22e-06	195	78	6	51e6cfecd66a874673d0b79a295489a358bddfd5
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	RSAD2 MYCBP2 VPS13C SYNE2 MED13L IFIT3	1.41e-06	200	78	6	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	COVID-19\|World / Disease, condition lineage and cell class	RSAD2 MYCBP2 VPS13C SYNE2 MED13L IFIT3	1.41e-06	200	78	6	7dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_2-Mgp\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	PIEZO2 TIMP1 AOX1 MYZAP TNFRSF11B	2.64e-06	124	78	5	b0ed84522180f8cea541461faf7882c57abf8cd4
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_2\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	PIEZO2 TIMP1 AOX1 MYZAP TNFRSF11B	2.64e-06	124	78	5	231862f849d8ab73c6a44c782d33ef2f07661baf
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	ADK MAK SMC6 SAV1 ADAM28	1.00e-05	163	78	5	6bed27d2f67a430a847da5eb47878d14b4949c45
ToppCell	normal_Lung-Fibroblasts-Mesothelial_cells\|normal_Lung / Location, Cell class and cell subclass	TPM2 DPYS TIMP1 AOX1 TNFRSF11B	1.45e-05	176	78	5	f31d7234053085a82cf9d55aeedd1e04d34789c3
ToppCell	356C-Lymphocytic-NK_cells-NK_cell_A2\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	ADAM19 BTK AOX1 SAV1 FAM216A	1.45e-05	176	78	5	052b54c4337ca728974a106b6dbd3b72dd28eb23
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RSAD2 ERICH3 SYNE2 ARHGAP45 IFIT3	1.49e-05	177	78	5	d3e6c768b88b7906f3c7fdd00ba20842212c14b1
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RSAD2 ERICH3 SYNE2 ARHGAP45 IFIT3	1.49e-05	177	78	5	f8f101c772c043636bedd6b2ec81409b1d2599bf
ToppCell	facs-Trachea-3m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell-ciliated_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DRC7 CFAP54 MAK ERICH3 CCDC160	1.49e-05	177	78	5	3cfde67b93f3986312f5e74e42504214d966e7dc
ToppCell	facs-Trachea-3m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DRC7 CFAP54 MAK ERICH3 CCDC160	1.49e-05	177	78	5	12a52a12a87a31e501ced611f46a90d172ca7e35
ToppCell	COVID-19_Mild-Lymphoid_T/NK-NK_activated\|COVID-19_Mild / Disease group, lineage and cell class	RSAD2 ERICH3 SYNE2 ARHGAP45 IFIT3	1.49e-05	177	78	5	6978a22fef40c8b455342373abe7593f5ede0fa4
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	RSAD2 ERICH3 SYNE2 ARHGAP45 IFIT3	1.49e-05	177	78	5	936ab2b180a052387124f68d0c7f41c0b164e748
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	RSAD2 ERICH3 SYNE2 ARHGAP45 IFIT3	1.49e-05	177	78	5	d5aeda113afaa2425874394610344570c9078478
ToppCell	PBMC-Severe-Lymphocyte-B-B_cell-B_memory-B_memory-3\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ADK HAGHL SDR16C5 DNAH8 ADAM28	1.84e-05	185	78	5	91c9a3ea1afd97d35bd05648875d29b35fe09128
ToppCell	PBMC-Convalescent-Lymphocyte-B-B_cell-B_memory-B_memory-3\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	BTK SAV1 SDR16C5 DNAH8 ADAM28	1.84e-05	185	78	5	05e6eb78ead81268c1656e7ffe34f9cb7329b908
ToppCell	CV-Moderate-7\|Moderate / Virus stimulation, Condition and Cluster	ADAM19 MYCBP2 VPS13C CLTC PRKDC	1.84e-05	185	78	5	a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCell	droplet-Fat-SCAT-30m-Epithelial\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIEZO2 IPO7 RGS11 TFAP2A ADAM28	1.94e-05	187	78	5	5fada3c5a58c1890029ccbfff2608b33f8cd2df7
ToppCell	droplet-Fat-SCAT-30m-Epithelial-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIEZO2 IPO7 RGS11 TFAP2A ADAM28	1.94e-05	187	78	5	766e808138fc2cd623c2e6d57fcb5c7378da0e03
ToppCell	droplet-Fat-SCAT-30m-Epithelial-epithelial_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIEZO2 IPO7 RGS11 TFAP2A ADAM28	1.94e-05	187	78	5	f49d06600060deeb2fc1b1da5b93496535f20104
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ADK ADAM19 BTK SAV1 ADAM28	1.94e-05	187	78	5	d01926be1c8846a25fb6706e26b56b808b69f8f0
ToppCell	Multiple_Sclerosis-Lymphocyte-B-B_memory\|Multiple_Sclerosis / Disease, Lineage and Cell Type	ADK BTK SMC6 SDR16C5 ADAM28	1.99e-05	188	78	5	8da631b2c75441b7309f03e7d4c14f15f2367be6
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	VPS13C SYNE2 DYRK1A MED13L SUCO	1.99e-05	188	78	5	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	(1)_B_cell\|World / immune cells in Peripheral Blood (logTPM normalization)	ADK ADAM19 BTK SAV1 ADAM28	1.99e-05	188	78	5	642a334f2d5b6dc9df4a9fa0558833bd37bd3c58
ToppCell	(10)_B_cell\|World / immune cells in Peripheral Blood (logTPM normalization)	ADK ADAM19 BTK SAV1 ADAM28	1.99e-05	188	78	5	fa1346902021c3a6557555ada0fd37b29cf9d5ec
ToppCell	PBMC-Convalescent-Lymphocyte-B-B_cell-B_memory\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	BTK SAV1 SDR16C5 DNAH8 ADAM28	1.99e-05	188	78	5	b6ae707b033a17c75ca81f9194631ead1b63d170
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ADAM19 BTK SMC6 DNAH8 ADAM28	2.04e-05	189	78	5	2b53dae0e6e85b7139f8a9872fbebb3705b2f1bf
ToppCell	Multiple_Sclerosis-Lymphocyte-B\|Multiple_Sclerosis / Disease, Lineage and Cell Type	ADK ADAM19 BTK SMC6 ADAM28	2.04e-05	189	78	5	864f666b1e8557a689320075036920e3ac589b8b
ToppCell	remission-B_memory\|remission / disease stage, cell group and cell class	BTK SAV1 SDR16C5 DNAH8 ADAM28	2.04e-05	189	78	5	a7b434a5d2cc7c3952cb8f16d11219b691c6c2b6
ToppCell	Healthy_donor-B_memory\|Healthy_donor / disease group, cell group and cell class (v2)	ADK ADAM19 SDR16C5 DNAH8 ADAM28	2.10e-05	190	78	5	46104a521f00d399315deca86699cb261b2795d6
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TPM2 ADAM19 MICAL2 AOX1 LAMA2	2.10e-05	190	78	5	562ee3b025c29edf07b8b344323edb49d82f1c7e
ToppCell	remission-B_memory\|World / disease stage, cell group and cell class	BTK SAV1 SDR16C5 DNAH8 ADAM28	2.10e-05	190	78	5	c3f55f752e47b5a71e111367cdbed4a39ab5cb21
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TPM2 ADAM19 MICAL2 AOX1 LAMA2	2.10e-05	190	78	5	f5fb989afabb49d64d91324570cd8c80a4b9e67d
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_B-B_naive\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ADK ADAM19 BTK SMC6 ADAM28	2.10e-05	190	78	5	e63945fa1dcd58bee129f1dd0c23b64a76241554
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_B-B_naive-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ADK ADAM19 BTK SMC6 ADAM28	2.10e-05	190	78	5	fa65bc5a178ae0c80a9bd4b282e4539493128a64
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_B\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ADK ADAM19 BTK SMC6 ADAM28	2.15e-05	191	78	5	8dda37ebf74b587129795f61541cc511ec97a314
ToppCell	COVID-19_Convalescent-Lymphoid_B-B_memory\|COVID-19_Convalescent / Disease group, lineage and cell class	BTK SAV1 SDR16C5 DNAH8 ADAM28	2.15e-05	191	78	5	4a853cd2434b0f5b18e1f853c37515845046c88b
ToppCell	facs-Lung-3m-Epithelial-airway_epithelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DRC7 MAK ERICH3 TCP11 ADAM28	2.15e-05	191	78	5	6a8fc9dc1a4c7115862e8f20204fa2f95e50e22f
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_B-B_mem\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ADK SMC6 SDR16C5 DNAH8 ADAM28	2.20e-05	192	78	5	75ce635d669ff77d1fd54e10467f21d5e5d67b08
ToppCell	healthy_donor-Lymphocytic-B_cell\|healthy_donor / Disease condition, Lineage, Cell class and subclass	ADAM19 BTK SMC6 SAV1 ADAM28	2.20e-05	192	78	5	7d9e5772b6e531b50ed4e4d6304ef11235f27f37
ToppCell	(100)_CD19+_Naive_B_cell\|World / immune cells in Peripheral Blood (logTPM normalization)	ADK ADAM19 BTK SAV1 ADAM28	2.20e-05	192	78	5	ae7e6ed7b6cc1dd45bc0547783515beecad7792a
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_B-B_mem-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ADK SMC6 SDR16C5 DNAH8 ADAM28	2.20e-05	192	78	5	80a71ab3434076803466ccac0df73468889c7dd3
ToppCell	healthy_donor-Lymphocytic-B_cell-\|healthy_donor / Disease condition, Lineage, Cell class and subclass	ADAM19 BTK SMC6 SAV1 ADAM28	2.20e-05	192	78	5	975312f9d6cede4d4f5b737e481e5c73accc8c50
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_intermediate\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ADAM19 SMC6 SIK1 DNAH8 ADAM28	2.26e-05	193	78	5	7cc10e8b51091869d46e462f3214999e7b5348b1
ToppCell	normal-na-Lymphocytic_B-B_cell-female\|normal / PBMC cell types (v2) per disease, treatment status, and sex	ADK ADAM19 BTK SMC6 ADAM28	2.26e-05	193	78	5	4fbf559771c367a6f5a03e0a5ef33366c118ddbf
ToppCell	normal-na-Lymphocytic_B-B_cell\|normal / PBMC cell types (v2) per disease, treatment status, and sex	ADK ADAM19 BTK SMC6 ADAM28	2.26e-05	193	78	5	2fd1cc050c775360cd53872fd405cf78288d7c4d
ToppCell	normal-na-Lymphocytic_B\|normal / PBMC cell types (v2) per disease, treatment status, and sex	ADK ADAM19 BTK SMC6 ADAM28	2.26e-05	193	78	5	5fe436b8da06c537b61d18aba8a24b0c8b1895bb
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_B\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ADAM19 BTK SMC6 SAV1 ADAM28	2.26e-05	193	78	5	6e6c5ae39ea880ba809019a7d39f50e4e02007ed
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_B-B_cell\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ADAM19 BTK SMC6 SAV1 ADAM28	2.26e-05	193	78	5	c04ac5884be4245b75d211046f04d76ae0cfb998
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ADAM19 BTK SMC6 SAV1 ADAM28	2.26e-05	193	78	5	749faa5c592ee354733f5a7363a4277ef3462b93
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_intermediate\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	ADAM19 SMC6 SIK1 DNAH8 ADAM28	2.32e-05	194	78	5	2b61023a602d336ed0de174e9141046173db34e6
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-lymphocytic-B_lymphocytic-B_cell\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ADAM19 MYCBP2 VPS13C SMC6 ADAM28	2.32e-05	194	78	5	ff661419b697aef51a53fdeac8d37d870d65f491
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibro-meso-mesothelial_cell-Mesothelium\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TPM2 DPYS TIMP1 AOX1 TNFRSF11B	2.32e-05	194	78	5	c578cf7c6b4d6f31f87dde8845de5b3891f16822
ToppCell	COVID-19_Mild-Lymphoid_B-B_intermediate\|COVID-19_Mild / Disease group, lineage and cell class	ADAM19 SMC6 SIK1 DNAH8 ADAM28	2.32e-05	194	78	5	bf6f72a489c62cbf1a679552d8c5eaaaa0b99d33
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_B-B_naive-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ADK ADAM19 BTK SMC6 ADAM28	2.32e-05	194	78	5	83554ba6a789750a39af58537fd7044ce20d3f02
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_B-B_naive\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ADK ADAM19 BTK SMC6 ADAM28	2.32e-05	194	78	5	56286db641cfb270e52f33989b8bf7b14d45010a
ToppCell	PBMC-Control-Lymphocyte-B\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	ADAM19 BTK SMC6 SAV1 ADAM28	2.32e-05	194	78	5	39121c7d537ac103f6959271d814fd327be7114f
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_intermediate-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ADAM19 SMC6 SIK1 DNAH8 ADAM28	2.32e-05	194	78	5	f2486b19ac52a48d19f80b38a5536bee3dad745b
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibro-meso\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TPM2 DPYS TIMP1 AOX1 TNFRSF11B	2.32e-05	194	78	5	f4286ae7bb8350c42d50727ee8688b80129714f6
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibro-meso-mesothelial_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TPM2 DPYS TIMP1 AOX1 TNFRSF11B	2.32e-05	194	78	5	79baee8b35b7707bbeb07c73b5e17b68bcd7bbc2
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibro-meso\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TPM2 DPYS TIMP1 AOX1 TNFRSF11B	2.32e-05	194	78	5	f6e348f1f35c526cad6c349f1fdd0bd92d18aa3c
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_B-B_mem\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ADK SMC6 SDR16C5 DNAH8 ADAM28	2.32e-05	194	78	5	40c7f9bd69a8e843b81972e25a67f591021415dd
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibro-meso-mesothelial_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TPM2 DPYS TIMP1 AOX1 TNFRSF11B	2.32e-05	194	78	5	87461bd6d7f702c0a0f5e0c8ace3049125a51f9a
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibro-meso-mesothelial_cell-Mesothelium-Mesothelium_L.2.6.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TPM2 DPYS TIMP1 AOX1 TNFRSF11B	2.32e-05	194	78	5	421344cc4b601d9745fa72d0af3124dab11d1d27
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibro-meso-mesothelial_cell-Mesothelium\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TPM2 DPYS TIMP1 AOX1 TNFRSF11B	2.32e-05	194	78	5	ce599ed0dc181aea0584e426636de5098f34ebe6
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ADAM19 MYCBP2 VPS13C MCMDC2 SMARCAD1	2.37e-05	195	78	5	4b9663509cc5e3f409f6d0d37640cb301a827d98
ToppCell	3'-Adult-LargeIntestine-Hematopoietic-B_cells\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADAM19 HAGHL BTK ARHGAP45 ADAM28	2.37e-05	195	78	5	daacbccf2a6a5ce1f0e3d1743a475076b4411c56
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_B\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ADK ADAM19 BTK SMC6 ADAM28	2.37e-05	195	78	5	9355dd84350f98cb33466acdfd90a39c50c9e39f
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-SMC_COL-D\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TPM2 TIMP1 MICAL2 AOX1 LAMA2	2.37e-05	195	78	5	78cfde21dde4b877fc76c8b0d5ddaabe44b912d7
ToppCell	control-Lymphocytic-B_cells_1\|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	ADAM19 BTK SMC6 SAV1 ADAM28	2.37e-05	195	78	5	ff7956624b36df34e55295b295a71585accf07bd
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYCBP2 VPS13C CLTC SCAPER RGS11	2.37e-05	195	78	5	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	ASK428-Epithelial-Transformed_epithelium\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	TPM2 DPYS TIMP1 RABGEF1 TNFRSF11B	2.37e-05	195	78	5	c750602c765a51075ba6ede78e3ba80b62374481
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYCBP2 VPS13C CLTC SCAPER RGS11	2.37e-05	195	78	5	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ADAM19 MYCBP2 VPS13C MCMDC2 SMARCAD1	2.43e-05	196	78	5	c9fb81a0578db6d278b8582d7b3add6c407e6dcf
ToppCell	saliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ADAM19 SMC6 MCMDC2 DNAH8 ADAM28	2.43e-05	196	78	5	0175b097ad1338a07afebe3b5c7fd0bb0bb950f7
ToppCell	3'-Adult-LargeIntestine-Hematopoietic-B_cells-Memory_B\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADAM19 HAGHL BTK ARHGAP45 ADAM28	2.43e-05	196	78	5	c7363794fb731848e4343b3a4e4f800f9c81999a
ToppCell	mild_COVID-19_(asymptomatic)\|World / disease group, cell group and cell class (v2)	DPYS RSAD2 MED13L MYZAP IFIT3	2.43e-05	196	78	5	8cb3dcb3e5732f4bb060c87ca339b8997a1a8cd4
ToppCell	mild-Lymphocytic-B_cells_1\|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	ADAM19 BTK SMC6 SAV1 ADAM28	2.43e-05	196	78	5	1988088dd7e1ba947339fd1331beed482955e607
ToppCell	COVID-19_Mild-Classical_Monocyte-cMono_4\|Classical_Monocyte / Disease condition and Cell class	RSAD2 TIMP1 MED13L ARHGAP45 IFIT3	2.49e-05	197	78	5	e666f6580e9a20b5e550f02125706db17eec8510
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-B\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CFAP54 ADAM19 BTK DNAH8 ADAM28	2.49e-05	197	78	5	0f489d26e4013d1b5a90559856ed2de32a0bb772
ToppCell	severe-B_memory\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ADK HAGHL SMC6 DNAH8 ADAM28	2.55e-05	198	78	5	88649dc642193bda5e8eff3f79c832807d5e200a
ToppCell	control-B_naive\|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ADK ADAM19 BTK SAV1 ADAM28	2.55e-05	198	78	5	c012b8fbfa8bbc5014217f47acf9177470d8a65a
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-B-B_intermediate\|COVID-19_Mild / Disease, condition lineage and cell class	ADAM19 SMC6 SIK1 DNAH8 ADAM28	2.61e-05	199	78	5	1c6a08d01f6c1a2a4b6587d3a4522efbd03275e1
ToppCell	COVID-19-COVID-19_Convalescent-Lymphocyte-B-B_memory\|COVID-19_Convalescent / Disease, condition lineage and cell class	BTK SAV1 SDR16C5 DNAH8 ADAM28	2.61e-05	199	78	5	5bbda86486910d053ca51b9caee487d78f6462cb
ToppCell	MS-Multiple_Sclerosis-Lymphocyte-B-B_memory\|Multiple_Sclerosis / Disease, condition lineage and cell class	ADK BTK SMC6 SDR16C5 ADAM28	2.61e-05	199	78	5	ae2979c0d2711580863d3b751f6ff1e3abdfd90e
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Mesothelial-1\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	TPM2 DPYS TIMP1 AOX1 TNFRSF11B	2.68e-05	200	78	5	c800f20adedf4ca736c740510889e92d8bf0ba44
ToppCell	VE\|World / Condition, Cell_class and T cell subcluster	RSAD2 MYCBP2 VPS13C SYNE2 IFIT3	2.68e-05	200	78	5	8ae7cb81de3ffac5acdf3466d4b516d80cac95d3
ToppCell	MS-Multiple_Sclerosis-Lymphocyte-B\|Multiple_Sclerosis / Disease, condition lineage and cell class	ADK ADAM19 BTK SMC6 ADAM28	2.68e-05	200	78	5	082b3be49fa9d65ed8351d4e80680583f8735207
ToppCell	mild-B_intermediate\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ADAM19 SMC6 SIK1 DNAH8 ADAM28	2.68e-05	200	78	5	fe815824e9e4be3f3db73610e3814a7fd533da65
ToppCell	Parenchyma_COVID-19-Stromal-TX-Mesothelial-1\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	TPM2 DPYS TIMP1 AOX1 TNFRSF11B	2.68e-05	200	78	5	bf50e30d5cafb71c567e89580f62084d2f894170
Disease	Bardet-Biedl syndrome (implicated_via_orthology)	TBC1D32 SCAPER BBS2	2.78e-06	11	77	3	DOID:1935 (implicated_via_orthology)
Disease	Congenital muscular dystrophy (disorder)	SYNE2 LAMA2	1.00e-04	6	77	2	C0699743
Disease	ARTHROGRYPOSIS, DISTAL, TYPE 2B	TPM2 PIEZO2	1.00e-04	6	77	2	C1834523
Disease	Distal arthrogryposis	TPM2 PIEZO2	2.39e-04	9	77	2	cv:C0265213
Disease	substance abuse, antisocial behaviour measurement	SCAPER MYZAP	2.39e-04	9	77	2	EFO_0007052, MONDO_0002491
Disease	meningitis	CACNA1E SCAPER	3.64e-04	11	77	2	MONDO_0021108
Disease	ceramide measurement	ADAM19 MICAL2 SYNE2 BBS2 ARHGAP45	3.81e-04	235	77	5	EFO_0010222
Disease	Mental Retardation, Psychosocial	ADK KIFBP SCAPER MED13L	4.89e-04	139	77	4	C0025363
Disease	Profound Mental Retardation	ADK KIFBP SCAPER MED13L	4.89e-04	139	77	4	C0020796
Disease	Mental deficiency	ADK KIFBP SCAPER MED13L	4.89e-04	139	77	4	C0917816
Disease	Hypercalcemia	KL TNFRSF11B	5.15e-04	13	77	2	C0020437
Disease	Milk-Alkali Syndrome	KL TNFRSF11B	5.15e-04	13	77	2	C0026141
Disease	N-acetylmethionine measurement	DOCK3 MICAL2	6.90e-04	15	77	2	EFO_0021427
Disease	eosinophil percentage of leukocytes	DOCK3 KIFBP ADAM19 DYRK1A SIK2 PRKDC ARHGAP45 TNFRSF11B	7.28e-04	746	77	8	EFO_0007991
Disease	syndromic intellectual disability (implicated_via_orthology)	DYRK1A ANAPC7	7.88e-04	16	77	2	DOID:0050888 (implicated_via_orthology)
Disease	autism spectrum disorder (is_implicated_in)	CYFIP1 DYRK1A	7.88e-04	16	77	2	DOID:0060041 (is_implicated_in)
Disease	plasma beta-amyloid 1-40 measurement	SAV1 PDS5A	8.91e-04	17	77	2	EFO_0005659
Disease	Intellectual Disability	ADK CACNA1E KIFBP SUPT16H SCAPER MED13L	1.12e-03	447	77	6	C3714756
Disease	Prostatic Neoplasms	PMS1 AOX1 PDS5A SMARCAD1 PRKDC ADAM28 NOL8	1.14e-03	616	77	7	C0033578
Disease	Malignant neoplasm of prostate	PMS1 AOX1 PDS5A SMARCAD1 PRKDC ADAM28 NOL8	1.14e-03	616	77	7	C0376358
Disease	temporal lobe epilepsy (is_marker_for)	ADK CYFIP1	1.24e-03	20	77	2	DOID:3328 (is_marker_for)
Disease	mean platelet volume	PDS5B ADAM19 TIMP1 SYNE2 DYRK1A SAV1 STIP1 MMAB ARHGAP45	1.34e-03	1020	77	9	EFO_0004584
Disease	lung adenocarcinoma (is_marker_for)	ABCE1 BTK ADAM28	1.45e-03	85	77	3	DOID:3910 (is_marker_for)
Disease	Down syndrome (is_marker_for)	TIMP1 DYRK1A	1.50e-03	22	77	2	DOID:14250 (is_marker_for)
Disease	Retinitis Pigmentosa	MAK SCAPER BBS2	2.58e-03	104	77	3	C0035334

Protein segments in the cluster

Peptide	Gene	Start	Entry
IMAKQILDLYMLYKL	ARID3B	241	Q8IVW6
EYKLNMMKRDHQKYI	ERICH3	51	Q5RHP9
YDLAVMIINYGKKML	CFAP54	1221	Q96N23
QFYKESLMKVMPYVD	ADK	221	P55263
AMIALNTVVLMMKYY	CACNA1E	1486	Q15878
TQESKEYKEMMHYLK	TBC1D32	101	Q96NH3
EYKEMMHYLKNIMIA	TBC1D32	106	Q96NH3
VFEMANYVNMLYKKL	ADAM28	231	Q9UKQ2
LKKVVALYDYMPMNA	BTK	216	Q06187
MKREDLNSMKYVELY	ADAM19	201	Q9H013
KPYDIMAEVYRAMKQ	PRKAA2	411	P54646
YLTEALKAMDKMYLS	TFAP2A	401	P05549
LLELMNKHDTEMKYY	DYRK1A	206	Q13627
KEINYFMYTMKKFLI	ADCY10	491	Q96PN6
VIEMGLLKMDNAYKF	AOX1	886	Q06278
KEAMMGLAQIYKKYA	PDS5B	406	Q9NTI5
EAILQEKMYLYMPKL	SDR16C5	256	Q8N3Y7
KEAMMGLAQLYKKYC	PDS5A	416	Q29RF7
KIMDQIEKYIMTRLY	RABGEF1	206	Q9UJ41
DAQLHIYMLMKKDSY	RGS11	391	O94810
MKVKVIPVLEDNYMY	HAGHL	1	Q6PII5
LYGKDMKERALIDMY	GSTA5	81	Q7RTV2
YKMAECYTMLKQDKD	ANAPC7	106	Q9UJX3
KEASMMEYVLYSLDL	CYFIP1	656	Q7L576
LLYAKNMAKYMKDLI	ARHGAP45	286	Q92619
NMAKYMKDLISYLEK	ARHGAP45	291	Q92619
YKYAVQLVEMLDMSV	LONP2	151	Q86WA8
MKDEQVFYIQYLKSM	MED13L	1736	Q71F56
EMLMIVIKYKDYFPV	MAGEC2	166	Q9UBF1
MSNLKMKEAALIYLD	MCMDC2	1	Q4G0Z9
FMAYKDLYMVTDLEL	DPYS	161	Q14117
DTKYLEMIYSMCKKV	IPO7	711	O95373
MLIEKAKDFYEQMQL	JRK	111	O75564
MLLCRYLNEEYKKKM	DNAH8	1081	Q96JB1
YKMLYGLENMTQELK	LAMA2	1606	P24043
KLPEVSKEMYYNIAM	NOL8	981	Q76FK4
SKEMYYNIAMDLKEI	NOL8	986	Q76FK4
PMMKLVYKLQAEDYK	SMPD4	131	Q9NXE4
TANEEEVKKMCMYKY	ABCE1	336	P61221
DMKTMKSRYMELYDL	BBS2	636	Q9BXC9
KILDKYGDMRVMMAY	DOCK3	1061	Q8IZD9
FQEFLRKMYEALKEM	FANCC	41	Q00597
MIEALKQYAMDYSNK	IFIT3	306	O14879
EEMKSYYELEMAKIR	CCDC160	261	A6NGH7
PMEHTKKLLYQYEAM	DRC7	661	Q8IY82
YMKENLYQLMKDRNK	MAK	81	P20794
MYYLKKFIMETLKAI	KL	431	Q9UEF7
SIAKIYNANYLKMLM	FAM216A	116	Q8WUB2
YITKEEMLAIMKSIY	KCNIP3	181	Q9Y2W7
KEVLMMLDNYVRDFK	SCAPER	131	Q9BY12
IKAVDAPVMAMKYYT	PMS1	61	P54277
YYDMMDLKVAIADRL	KIFBP	481	Q96EK5
DKLSMVMYLSKFYEL	MICAL2	606	O94851
YAAMKEGNQEKIYMK	MMAB	226	Q96EY8
MKDYTKAMDVYQKAL	STIP1	441	P31948
YYTAEKLKEMSQLML	SMARCAD1	791	Q9H4L7
KMKDSYLILDEYMRF	RSAD2	296	Q8WXG1
ENIMEKLRIKYSEMY	SYNE2	3636	Q8WXH0
IIKLYQVMETKDMLY	SIK1B	86	A0A0B4J2F2
IIKLYQVMETKDMLY	SIK1	86	P57059
KLYQVMETKSMLYLV	SIK2	81	Q9H0K1
METKSMLYLVTEYAK	SIK2	86	Q9H0K1
KEARYIAITMMKVYE	MYCBP2	2366	O75592
DMVIVYKDYSKKVTM	SUPT16H	856	Q9Y5B9
AYEYSRKMMMKQLEA	SLC25A2	286	Q9BXI2
MPYFIQVMKEYLTKV	CLTC	1596	Q00610
MQKLKLIRMCPYYEE	CNBD1	311	Q8NA66
YEIKMTKMYKGFQAL	TIMP1	61	P01033
DLDTYQGMLKLLFMK	SAV1	331	Q9H4B6
KIGMNCDYYMEEKVL	TCP11	61	Q8WWU5
KEEEYKLMYGMLFSI	TRAPPC1	31	Q9Y5R8
TMYKLYQKLFLEMIG	TNFRSF11B	376	O00300
EGKIVMYKIIYMVLF	PIEZO2	701	Q9H5I5
LEQMKEDYSYIMETK	SMC6	216	Q96SB8
YDMTAKAYLKKISMQ	VPS13C	1466	Q709C8
MMEKIKSYVNYVLSE	TERF1	236	P54274
LDEQMYAKYVKMFIK	SUCO	411	Q9UBS9
LSAMKEFAYMKALYE	RIOK2	156	Q9BVS4
QITKKMGYYKILDVM	PRKDC	1866	P78527
VNKKNIEKMYERMYA	PRKDC	3601	P78527
MLAVMKKLTYDEEYN	XPOT	376	O43592
LEDEVYAQKMKYKAI	TPM2	256	P07951
DADYAIKIMNMIKLY	SF3B4	66	Q15427
EVMREMTKKLYSQYE	MYZAP	236	P0CAP1