Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ferroxidase activity	FTH1 FTMT	1.15e-04	6	56	2	GO:0004322
GeneOntologyMolecularFunction	oxidoreductase activity, acting on metal ions, oxygen as acceptor	FTH1 FTMT	1.15e-04	6	56	2	GO:0016724
GeneOntologyMolecularFunction	ferric iron binding	FTH1 FTMT	4.18e-04	11	56	2	GO:0008199
GeneOntologyCellularComponent	clathrin-coated pit	CLTCL1 ACKR3 SNX9 FCHO1	6.28e-05	80	56	4	GO:0005905
GeneOntologyCellularComponent	microtubule	EFHC1 KIF3B BCL2L11 NICN1 ASPM DYRK1A KIF3C KLC1	8.21e-05	533	56	8	GO:0005874
GeneOntologyCellularComponent	kinesin complex	KIF3B KIF3C KLC1	3.07e-04	49	56	3	GO:0005871
GeneOntologyCellularComponent	clathrin-coated vesicle	CLTCL1 HLA-DQB1 HLA-DRB4 SNX9 FCHO1	4.28e-04	237	56	5	GO:0030136
GeneOntologyCellularComponent	MHC class II protein complex	HLA-DQB1 HLA-DRB4	9.34e-04	17	56	2	GO:0042613
GeneOntologyCellularComponent	late endosome membrane	WDR91 HLA-DQB1 HLA-DRB4 LAMTOR3	1.35e-03	179	56	4	GO:0031902
GeneOntologyCellularComponent	lysosome	TINAGL1 HLA-DQB1 HLA-DRB4 FTH1 LAMTOR3 SMPD1 ITM2C TMBIM1	1.35e-03	811	56	8	GO:0005764
GeneOntologyCellularComponent	lytic vacuole	TINAGL1 HLA-DQB1 HLA-DRB4 FTH1 LAMTOR3 SMPD1 ITM2C TMBIM1	1.35e-03	811	56	8	GO:0000323
GeneOntologyCellularComponent	somatodendritic compartment	PTPN6 EFHC1 KIF3B SYNE1 SORCS2 DYRK1A KIF3C ITGA1 ARHGEF15 KLC1	1.41e-03	1228	56	10	GO:0036477
GeneOntologyCellularComponent	MHC protein complex	HLA-DQB1 HLA-DRB4	2.20e-03	26	56	2	GO:0042611
GeneOntologyCellularComponent	late endosome	WDR91 CLTCL1 HLA-DQB1 HLA-DRB4 LAMTOR3	2.37e-03	348	56	5	GO:0005770
GeneOntologyCellularComponent	clathrin-coated endocytic vesicle	CLTCL1 HLA-DQB1 HLA-DRB4	2.52e-03	101	56	3	GO:0045334
GeneOntologyCellularComponent	polymeric cytoskeletal fiber	EFHC1 KIF3B BCL2L11 NICN1 ASPM DYRK1A KIF3C KLC1	2.58e-03	899	56	8	GO:0099513
GeneOntologyCellularComponent	coated vesicle	CLTCL1 HLA-DQB1 HLA-DRB4 SNX9 FCHO1	2.74e-03	360	56	5	GO:0030135
GeneOntologyCellularComponent	vacuole	TINAGL1 HLA-DQB1 HLA-DRB4 FTH1 LAMTOR3 SMPD1 ITM2C TMBIM1	2.84e-03	913	56	8	GO:0005773
GeneOntologyCellularComponent	midbody	PTPN13 KIF3B SYNE1 ASPM	2.95e-03	222	56	4	GO:0030496
GeneOntologyCellularComponent	endosome	WDR91 CLTCL1 HLA-DQB1 ACKR3 HLA-DRB4 SORCS2 LAMTOR3 SMPD1 TMBIM1	3.61e-03	1167	56	9	GO:0005768
GeneOntologyCellularComponent	supramolecular fiber	EFHC1 KIF3B BCL2L11 SYNE1 NICN1 ASPM DYRK1A KIF3C KLC1	3.86e-03	1179	56	9	GO:0099512
GeneOntologyCellularComponent	lumenal side of endoplasmic reticulum membrane	HLA-DQB1 HLA-DRB4	3.96e-03	35	56	2	GO:0098553
GeneOntologyCellularComponent	supramolecular polymer	EFHC1 KIF3B BCL2L11 SYNE1 NICN1 ASPM DYRK1A KIF3C KLC1	4.04e-03	1187	56	9	GO:0099081
GeneOntologyCellularComponent	microtubule end	ASPM KIF3C	4.66e-03	38	56	2	GO:1990752
GeneOntologyCellularComponent	endosome membrane	WDR91 HLA-DQB1 HLA-DRB4 SORCS2 LAMTOR3 TMBIM1	5.33e-03	602	56	6	GO:0010008
GeneOntologyCellularComponent	secretory vesicle	PTPN6 SLC9A4 FTH1 RABAC1 LAMTOR3 SMPD1 KIF3C ITGA1 TMBIM1	5.54e-03	1246	56	9	GO:0099503
GeneOntologyCellularComponent	membrane protein complex	PTPN6 CLTCL1 KCNQ5 HLA-DQB1 SYNE1 HLA-DRB4 BEST4 LAMTOR3 ITGA1 ATP4A	5.95e-03	1498	56	10	GO:0098796
GeneOntologyCellularComponent	clathrin-coated vesicle membrane	CLTCL1 HLA-DQB1 HLA-DRB4	7.19e-03	147	56	3	GO:0030665
GeneOntologyCellularComponent	lumenal side of membrane	HLA-DQB1 HLA-DRB4	7.35e-03	48	56	2	GO:0098576
GeneOntologyCellularComponent	ciliary tip	KIF3B KIF3C	7.35e-03	48	56	2	GO:0097542
GeneOntologyCellularComponent	cytoplasmic vesicle membrane	WDR91 SLC9A4 CLTCL1 HLA-DQB1 HLA-DRB4 SORCS2 LAMTOR3 SNX9 TMBIM1	7.52e-03	1307	56	9	GO:0030659
GeneOntologyCellularComponent	dendrite	PTPN6 KIF3B SYNE1 SORCS2 DYRK1A KIF3C ARHGEF15	7.71e-03	858	56	7	GO:0030425
GeneOntologyCellularComponent	dendritic tree	PTPN6 KIF3B SYNE1 SORCS2 DYRK1A KIF3C ARHGEF15	7.81e-03	860	56	7	GO:0097447
GeneOntologyCellularComponent	lysosomal membrane	HLA-DQB1 HLA-DRB4 LAMTOR3 ITM2C TMBIM1	7.82e-03	462	56	5	GO:0005765
GeneOntologyCellularComponent	lytic vacuole membrane	HLA-DQB1 HLA-DRB4 LAMTOR3 ITM2C TMBIM1	7.82e-03	462	56	5	GO:0098852
GeneOntologyCellularComponent	vesicle membrane	WDR91 SLC9A4 CLTCL1 HLA-DQB1 HLA-DRB4 SORCS2 LAMTOR3 SNX9 TMBIM1	8.20e-03	1325	56	9	GO:0012506
Domain	ASH	ASPM HYDIN	8.51e-06	2	55	2	IPR031549
Domain	ASH	ASPM HYDIN	8.51e-06	2	55	2	PF15780
Domain	FERRITIN_1	FTH1 FTMT	5.09e-05	4	55	2	PS00540
Domain	Ferritin-like_diiron	FTH1 FTMT	5.09e-05	4	55	2	IPR009040
Domain	FERRITIN_2	FTH1 FTMT	5.09e-05	4	55	2	PS00204
Domain	Ferritin	FTH1 FTMT	5.09e-05	4	55	2	IPR001519
Domain	FERRITIN_LIKE	FTH1 FTMT	5.09e-05	4	55	2	PS50905
Domain	Ferritin	FTH1 FTMT	5.09e-05	4	55	2	PF00210
Domain	Ferritin_DPS_dom	FTH1 FTMT	5.09e-05	4	55	2	IPR008331
Domain	Ferritin_CS	FTH1 FTMT	5.09e-05	4	55	2	IPR014034
Domain	-	FTH1 FTMT	8.47e-05	5	55	2	1.20.1260.10
Domain	Ferritin-rel	FTH1 FTMT	1.27e-04	6	55	2	IPR012347
Domain	MHC_II_b_N	HLA-DQB1 HLA-DRB4	2.36e-04	8	55	2	PD000328
Domain	MHC_II_beta	HLA-DQB1 HLA-DRB4	3.02e-04	9	55	2	PF00969
Domain	MHC_II_b_N	HLA-DQB1 HLA-DRB4	3.02e-04	9	55	2	IPR000353
Domain	MHC_II_beta	HLA-DQB1 HLA-DRB4	3.02e-04	9	55	2	SM00921
Domain	MHC_II_a/b_N	HLA-DQB1 HLA-DRB4	7.57e-04	14	55	2	IPR014745
Domain	-	HLA-DQB1 HLA-DRB4	7.57e-04	14	55	2	3.10.320.10
Domain	Ferritin-like_SF	FTH1 FTMT	7.57e-04	14	55	2	IPR009078
Domain	PTPc	PTPN6 PTPN13	5.03e-03	36	55	2	SM00194
Domain	MHC_I/II-like_Ag-recog	HLA-DQB1 HLA-DRB4	5.59e-03	38	55	2	IPR011162
Domain	TYR_PHOSPHATASE_PTP	PTPN6 PTPN13	5.88e-03	39	55	2	PS50055
Domain	PTPase_domain	PTPN6 PTPN13	6.49e-03	41	55	2	IPR000242
Domain	Y_phosphatase	PTPN6 PTPN13	6.49e-03	41	55	2	PF00102
Domain	Kinesin_motor_CS	KIF3B KIF3C	6.49e-03	41	55	2	IPR019821
Domain	Kinesin-like_fam	KIF3B KIF3C	7.12e-03	43	55	2	IPR027640
Domain	KINESIN_MOTOR_1	KIF3B KIF3C	7.44e-03	44	55	2	PS00411
Domain	-	KIF3B KIF3C	7.44e-03	44	55	2	3.40.850.10
Domain	Kinesin_motor_dom	KIF3B KIF3C	7.44e-03	44	55	2	IPR001752
Domain	Kinesin	KIF3B KIF3C	7.44e-03	44	55	2	PF00225
Domain	KINESIN_MOTOR_2	KIF3B KIF3C	7.44e-03	44	55	2	PS50067
Domain	KISc	KIF3B KIF3C	7.44e-03	44	55	2	SM00129
Pathway	REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION	KIF3B HLA-DQB1 HLA-DRB4 KIF3C KLC1	6.63e-05	126	48	5	M705
Pathway	REACTOME_PD_1_SIGNALING	PTPN6 HLA-DQB1 HLA-DRB4	1.14e-04	28	48	3	M18810
Pubmed	Large-scale proteomics and phosphoproteomics of urinary exosomes.	PTPN6 PTPN13 KIF3B TM7SF3 FTH1 LAMTOR3 ITM2C RENBP ITGA1 SNX9 TMBIM1	5.60e-07	1016	56	11	19056867
Pubmed	Tissue-specific expression of ferritin H regulates cellular iron homoeostasis in vivo.	FTH1 FTMT	2.55e-06	2	56	2	16448386
Pubmed	Unique iron binding and oxidation properties of human mitochondrial ferritin: a comparative analysis with Human H-chain ferritin.	FTH1 FTMT	2.55e-06	2	56	2	15755449
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	DOCK5 EFHC1 PTPN13 KIF3B DYRK1A IPO13 MRPS35 KIF3C SNX9 KLC1 NUP205	7.04e-06	1321	56	11	27173435
Pubmed	Inhibition of SDF-1 receptors CXCR4 and CXCR7 attenuates acute pulmonary inflammation via the adenosine A2B-receptor on blood cells.	ADORA2B ACKR3	7.63e-06	3	56	2	28542132
Pubmed	Kinesin-2 KIF3AC and KIF3AB Can Drive Long-Range Transport along Microtubules.	KIF3B KIF3C	7.63e-06	3	56	2	26445448
Pubmed	Heterodimerization of Kinesin-2 KIF3AB Modulates Entry into the Processive Run.	KIF3B KIF3C	7.63e-06	3	56	2	27637334
Pubmed	Contribution of HLA class II genes, DRB401:01, DRB107:01, and DQB1*03:03:2 to clinical features of Vitiligo disease in Iranian population.	HLA-DQB1 HLA-DRB4	7.63e-06	3	56	2	34686989
Pubmed	Expression of KIF3C kinesin during neural development and in vitro neuronal differentiation.	KIF3B KIF3C	7.63e-06	3	56	2	11331403
Pubmed	Conditional deletion of ferritin H in mice induces loss of iron storage and liver damage.	FTH1 FTMT	7.63e-06	3	56	2	19492434
Pubmed	HLA class II allele and haplotype frequencies in iranian patients with acute myelogenous leukemia and control group.	HLA-DQB1 HLA-DRB4	7.63e-06	3	56	2	17237562
Pubmed	[Role of HLA-DR and HLA-DQ alleles in multibacillary leprosy and paucibacillary leprosy in the province of Chaco (Argentina)].	HLA-DQB1 HLA-DRB4	7.63e-06	3	56	2	18053473
Pubmed	Molecular diversity of HLA-DR4 haplotypes.	HLA-DQB1 HLA-DRB4	7.63e-06	3	56	2	3458223
Pubmed	cAMP signalling of Bordetella adenylate cyclase toxin through the SHP-1 phosphatase activates the BimEL-Bax pro-apoptotic cascade in phagocytes.	PTPN6 BCL2L11	7.63e-06	3	56	2	26334669
Pubmed	Kinesin-2 and photoreceptor cell death: requirement of motor subunits.	KIF3B KIF3C	7.63e-06	3	56	2	16337628
Pubmed	Association of HLA-DR and -DQ genes with narcolepsy in Koreans: comparison with two control groups, randomly selected subjects and DRB11501-DQB10602--positive subjects.	HLA-DQB1 HLA-DRB4	1.52e-05	4	56	2	17002906
Pubmed	Analysis of DR beta and DQ beta chain cDNA clones from a DR7 haplotype.	HLA-DQB1 HLA-DRB4	1.52e-05	4	56	2	3020127
Pubmed	HLA class II allele and haplotype frequencies in Iranian patients with leukemia.	HLA-DQB1 HLA-DRB4	1.52e-05	4	56	2	17893434
Pubmed	Fetal growth is increased by maternal type 1 diabetes and HLA DR4-related gene interactions.	HLA-DQB1 HLA-DRB4	1.52e-05	4	56	2	17310371
Pubmed	Two divergent routes of evolution gave rise to the DRw13 haplotypes.	HLA-DQB1 HLA-DRB4	1.52e-05	4	56	2	2212675
Pubmed	HLA class II alleles in systemic sclerosis patients with anti-RNA polymerase I/III antibody: associations with subunit reactivities.	HLA-DQB1 HLA-DRB4	1.52e-05	4	56	2	14677183
Pubmed	Human leukocyte antigen association in idiopathic thrombotic thrombocytopenic purpura: evidence for an immunogenetic link.	HLA-DQB1 HLA-DRB4	1.52e-05	4	56	2	19922436
Pubmed	A comparison of HLA-DR and -DQ allele and haplotype frequencies in Trinidadian populations of African, South Asian, and mixed ancestry.	HLA-DQB1 HLA-DRB4	2.54e-05	5	56	2	12392858
Pubmed	Association between psoriasis vulgaris and MHC-DRB, -DQB genes as a contribution to disease diagnosis.	HLA-DQB1 HLA-DRB4	2.54e-05	5	56	2	15908298
Pubmed	HLA-DQ8 and the HLA-DQ8-DR4 haplotype are positively associated with the hevein-specific IgE immune response in health care workers with latex allergy.	HLA-DQB1 HLA-DRB4	2.54e-05	5	56	2	12209103
Pubmed	Visual hallucinations and HLA class II antigens in cortical dementia.	HLA-DQB1 HLA-DRB4	2.54e-05	5	56	2	20606439
Pubmed	HLA-DR and DQB1 gene polymorphism in the North-western Colombian population.	HLA-DQB1 HLA-DRB4	2.54e-05	5	56	2	12144632
Pubmed	Nephropathy in type 1 diabetes is diminished in carriers of HLA-DRB1*04: the genetics of kidneys in diabetes (GoKinD) study.	HLA-DQB1 HLA-DRB4	2.54e-05	5	56	2	18039812
Pubmed	A comparison of molecular HLA-DR and DQ allele profiles forming DR51-, DR52-, and DR53-related haplotypes in five ethnic Thai populations from mainland southeast Asia.	HLA-DQB1 HLA-DRB4	3.80e-05	6	56	2	11082517
Pubmed	Association of immune responses to mycobacterium tuberculosis peptide antigens with host genetic factors.	HLA-DQB1 HLA-DRB4	3.80e-05	6	56	2	17153701
Pubmed	Genetic association of type 1 diabetes in an Azerbaijanian population: the HLA-DQ, -DRB1*04, the insulin gene, and CTLA4.	HLA-DQB1 HLA-DRB4	3.80e-05	6	56	2	16629714
Pubmed	HLA-B, -DRB1/3/4/5, and -DQB1 gene polymorphisms in human immunodeficiency virus-related Kaposi's sarcoma.	HLA-DQB1 HLA-DRB4	3.80e-05	6	56	2	15902698
Pubmed	The von Hippel-Lindau tumour suppressor interacts with microtubules through kinesin-2.	KIF3B KLC1	3.80e-05	6	56	2	17825299
Pubmed	HLA class II DNA typing in a large series of European patients with systemic lupus erythematosus: correlations with clinical and autoantibody subsets.	HLA-DQB1 HLA-DRB4	3.80e-05	6	56	2	11997714
Pubmed	HLA-DRB1*1101: a significant risk factor for sarcoidosis in blacks and whites.	HLA-DQB1 HLA-DRB4	3.80e-05	6	56	2	14508706
Pubmed	Anti-cofactor autoantibodies in systemic lupus erythematosus: prevalence, clinical and HLA class II associations.	HLA-DQB1 HLA-DRB4	5.32e-05	7	56	2	18569076
Pubmed	The impact of anti-HY responses on outcome in current and subsequent pregnancies of patients with recurrent pregnancy losses.	HLA-DQB1 HLA-DRB4	5.32e-05	7	56	2	20307907
Pubmed	Human leukocyte antigen class I and class II allele frequencies and HIV-1 infection associations in a Chinese cohort.	HLA-DQB1 HLA-DRB4	7.09e-05	8	56	2	17106278
Pubmed	Association of HY-restricting HLA class II alleles with pregnancy outcome in patients with recurrent miscarriage subsequent to a firstborn boy.	HLA-DQB1 HLA-DRB4	7.09e-05	8	56	2	19223392
Pubmed	Correlation between HLA and pityriasis rosea susceptibility in Brazilian blacks.	HLA-DQB1 HLA-DRB4	7.09e-05	8	56	2	16405603
Pubmed	HLA-A, B, Cw, DRB1, DRB3/4/5, DQB1 in German patients suffering from rapidly progressive periodontitis (RPP) and adult periodontitis (AP).	HLA-DQB1 HLA-DRB4	7.09e-05	8	56	2	12296785
Pubmed	The P4-type ATPase ATP11C is essential for B lymphopoiesis in adult bone marrow.	PTPN6 BCL2L11	9.10e-05	9	56	2	21423172
Pubmed	TIMP-2 mediated inhibition of angiogenesis: an MMP-independent mechanism.	PTPN6 ITGA1	9.10e-05	9	56	2	12887919
Pubmed	Roles of HLA-B, HLA-C and HLA-DPA1 incompatibilities in the outcome of unrelated stem-cell transplantation.	HLA-DQB1 HLA-DRB4	1.14e-04	10	56	2	12956878
Pubmed	Nesprin 1α2 is essential for mouse postnatal viability and nuclear positioning in skeletal muscle.	SYNE1 KLC1	1.14e-04	10	56	2	28533284
Pubmed	Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.	FAT4 SYNE1	1.39e-04	11	56	2	20351715
Pubmed	HIV-1 envelope protein is expressed on the surface of infected cells before its processing and presentation to class II-restricted T lymphocytes.	HLA-DQB1 HLA-DRB4	2.64e-04	15	56	2	8376762
Pubmed	Strategy for identifying dendritic cell-processed CD4+ T cell epitopes from the HIV gag p24 protein.	HLA-DQB1 HLA-DRB4	2.64e-04	15	56	2	22860026
Pubmed	Endocytosis of endogenously synthesized HIV-1 envelope protein. Mechanism and role in processing for association with class II MHC.	HLA-DQB1 HLA-DRB4	2.64e-04	15	56	2	7602119
Pubmed	The enhanced immune response to the HIV gp160/LAMP chimeric gene product targeted to the lysosome membrane protein trafficking pathway.	HLA-DQB1 HLA-DRB4	2.64e-04	15	56	2	9079699
Pubmed	AIDS and related syndromes as a viral-induced autoimmune disease of the immune system: an anti-MHC II disorder. Therapeutic implications.	HLA-DQB1 HLA-DRB4	2.64e-04	15	56	2	3489470
Pubmed	Efficient incorporation of HLA class II onto human immunodeficiency virus type 1 requires envelope glycoprotein packaging.	HLA-DQB1 HLA-DRB4	2.64e-04	15	56	2	10729169
Pubmed	Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA.	TINAGL1 KIF3B KCNQ5 TM7SF3	2.97e-04	198	56	4	27480124
Pubmed	Inhibition of CD4+ T cell function by the HIV envelope protein, gp120.	HLA-DQB1 HLA-DRB4	3.01e-04	16	56	2	2846691
Pubmed	Identification and structural analysis of residues in the V1 region of CD4 involved in interaction with human immunodeficiency virus envelope glycoprotein gp120 and class II major histocompatibility complex molecules.	HLA-DQB1 HLA-DRB4	3.01e-04	16	56	2	1978941
Pubmed	Identification of human CD4 residues affecting class II MHC versus HIV-1 gp120 binding.	HLA-DQB1 HLA-DRB4	3.01e-04	16	56	2	2543930
Pubmed	Human immunodeficiency virus type 1 Vpu protein interacts with CD74 and modulates major histocompatibility complex class II presentation.	HLA-DQB1 HLA-DRB4	3.01e-04	16	56	2	17959659
Pubmed	HIV-1 Nef promotes endocytosis of cell surface MHC class II molecules via a constitutive pathway.	HLA-DQB1 HLA-DRB4	3.83e-04	18	56	2	19620308
Pubmed	Reciprocal modulation of transcriptional activities between HIV-1 Tat and MHC class II transactivator CIITA.	HLA-DQB1 HLA-DRB4	3.83e-04	18	56	2	11118314
Pubmed	Tat competes with CIITA for the binding to P-TEFb and blocks the expression of MHC class II genes in HIV infection.	HLA-DQB1 HLA-DRB4	3.83e-04	18	56	2	10661406
Pubmed	A directed protein interaction network for investigating intracellular signal transduction.	FRZB MIPEP RABAC1 LAMTOR3 HACL1 SMPD1 HERC3 KLC1	4.16e-04	1124	56	8	21900206
Pubmed	The Role of Sorting Nexin 17 in Cardiac Development.	FAT4 FRZB	4.28e-04	19	56	2	34988124
Pubmed	HIV gp120 inhibits T cell activation by interfering with expression of costimulatory molecules CD40 ligand and CD80 (B71).	HLA-DQB1 HLA-DRB4	4.75e-04	20	56	2	7541827
Pubmed	The DNA sequence and analysis of human chromosome 6.	EFHC1 IL22RA2 KCNQ5 SYNE1 HLA-DRB4 SNX9	4.86e-04	622	56	6	14574404
Pubmed	HIV-1 Gag-virus-like particles induce natural killer cell immune responses via activation and maturation of dendritic cells.	HLA-DQB1 HLA-DRB4	5.24e-04	21	56	2	21778700
Pubmed	HIV-1 gp41 binding proteins and antibodies to gp41 could inhibit enhancement of human Raji cell MHC class I and II expression by gp41.	HLA-DQB1 HLA-DRB4	5.24e-04	21	56	2	8084338
Pubmed	Defining the membrane proteome of NK cells.	CLTCL1 KIF3B HLA-DQB1 RABAC1 ITGA1 LMBRD2 KLC1 NUP205	5.37e-04	1168	56	8	19946888
Pubmed	Role of HIV-1 Nef protein for virus replication in vitro.	HLA-DQB1 HLA-DRB4	6.30e-04	23	56	2	19770068
Pubmed	Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.	WDR91 CLTCL1 ZFP30 HACL1 SMPD1 FCHO1 KLC1	6.87e-04	925	56	7	28986522
Pubmed	Human immunodeficiency virus type-1 (HIV-1) Pr55gag virus-like particles are potent activators of human monocytes.	HLA-DQB1 HLA-DRB4	6.87e-04	24	56	2	18945465
Pubmed	Identification and classification of 16 new kinesin superfamily (KIF) proteins in mouse genome.	KIF3B KIF3C	7.46e-04	25	56	2	9275178
Pubmed	Screening the proteins that interact with calpain in a human heart cDNA library using a yeast two-hybrid system.	TINAGL1 SYNE1	7.46e-04	25	56	2	12358155
Pubmed	Adapters in lymphocyte signaling.	HLA-DQB1 HLA-DRB4	8.07e-04	26	56	2	11827988
Pubmed	Identification, partial characterization, and genetic mapping of kinesin-like protein genes in mouse.	KIF3B KIF3C	8.07e-04	26	56	2	9339368
Pubmed	Interactions of viral protein U (Vpu) with cellular factors.	HLA-DQB1 HLA-DRB4	8.71e-04	27	56	2	20012522
Pubmed	A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.	PTPN13 SYNE1 RABAC1 LMBRD2 SNX9 TMBIM1	1.03e-03	719	56	6	35337019
Pubmed	Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.	HLA-DQB1 ITGA1	1.08e-03	30	56	2	21946350
Pubmed	Inherited genetic variant predisposes to aggressive but not indolent prostate cancer.	FRZB SORCS2	1.08e-03	30	56	2	20080650
Pubmed	Polymorphisms in genes involved in neurodevelopment may be associated with altered brain morphology in schizophrenia: preliminary evidence.	ASPM SMPD1	1.08e-03	30	56	2	19054571
Pubmed	Misdirection of membrane trafficking by HIV-1 Vpu and Nef: Keys to viral virulence and persistence.	HLA-DQB1 HLA-DRB4	1.15e-03	31	56	2	21922073
Pubmed	The mechanism of phospholipase C-gamma1 regulation.	HLA-DQB1 HLA-DRB4	1.15e-03	31	56	2	11048639
Pubmed	Mitochondrial Raf1 Regulates Glutamine Catabolism.	PTPN13 MIPEP ASPM RENBP	1.21e-03	288	56	4	38496616
Pubmed	Immunoregulatory effects of HIV-1 Nef protein.	HLA-DQB1 HLA-DRB4	1.22e-03	32	56	2	19449444
Pubmed	Proteomic analysis and identification of cellular interactors of the giant ubiquitin ligase HERC2.	FTH1 ASPM ATP4A	1.48e-03	139	56	3	25476789
Pubmed	Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals.	ZFP30 SORCS2 ITM2C	1.58e-03	142	56	3	19851296
Pubmed	Association of genetic variants with hemorrhagic stroke in Japanese individuals.	ZFP30 SORCS2 ITM2C	1.61e-03	143	56	3	20198315
Interaction	FTMT interactions	DYRK1A FTMT	7.58e-06	2	56	2	int:FTMT
Cytoband	5p13.2	NADK2 LMBRD2	6.64e-04	31	56	2	5p13.2
Cytoband	7q33	WDR91 NUP205	1.16e-03	41	56	2	7q33
Cytoband	Ensembl 112 genes in cytogenetic band chr7q33	WDR91 NUP205	2.31e-03	58	56	2	chr7q33
Cytoband	Ensembl 112 genes in cytogenetic band chr2q37	IQCA1 ACKR3 ITM2C	2.69e-03	226	56	3	chr2q37
Cytoband	2q37.3	IQCA1 ACKR3	4.03e-03	77	56	2	2q37.3
Cytoband	Ensembl 112 genes in cytogenetic band chr12p11	TM7SF3 MRPS35	4.89e-03	85	56	2	chr12p11
GeneFamily	Protein tyrosine phosphatases, non-receptor type	PTPN6 PTPN13	6.11e-04	18	37	2	812
GeneFamily	C1-set domain containing	HLA-DQB1 HLA-DRB4	3.33e-03	42	37	2	591
GeneFamily	CD molecules\|I-set domain containing\|Immunoglobulin like domain containing\|Interleukin receptors\|TIR domain containing	IL22RA2 IL3RA	3.33e-03	42	37	2	602
GeneFamily	Histocompatibility complex\|C1-set domain containing	HLA-DQB1 HLA-DRB4	3.65e-03	44	37	2	588
GeneFamily	Kinesins\|Pleckstrin homology domain containing	KIF3B KIF3C	3.99e-03	46	37	2	622
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	ARHGEF19 ARHGEF15	8.05e-03	66	37	2	722
Coexpression	GSE19772_HCMV_INFL_VS_HCMV_INF_MONOCYTES_AND_PI3K_INHIBITION_DN	DOCK5 BCL2L11 TM7SF3 ITM2C SNX9 KLC1	4.33e-06	200	56	6	M7286
Coexpression	HE_LIM_SUN_FETAL_LUNG_C3_LYMPHATIC_ENDOTHELIAL_CELL	DOCK5 IQCA1 SYNE1 FRZB KIF3C ITGA1 PKHD1L1	1.66e-05	382	56	7	M45756
Coexpression	GSE34156_UNTREATED_VS_6H_NOD2_LIGAND_TREATED_MONOCYTE_UP	EFHC1 FTH1 LAMTOR3 ITGA1 TMBIM1	2.99e-05	168	56	5	M8665
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c04-COTL1\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	DOCK5 BCL2L11 SYNE1 RABAC1 ITM2C ITGA1	1.40e-07	193	55	6	778fcf8448e81fe18972d97ea8a30ab036d16fe5
ToppCell	COVID-19-Heart-Lymph_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DOCK5 ACKR3 KIF3C ITGA1 PKHD1L1	2.64e-06	177	55	5	326fde0734ef0d7272693966d346ca479b9d8147
ToppCell	droplet-Lung-LUNG-30m-Endothelial-Capillary_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TINAGL1 ACKR3 SYNE1 ITGA1 ARHGEF15	3.46e-06	187	55	5	52ffd4be374e329ac8d321063f061b826d252956
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TINAGL1 KCNQ5 SYNE1 FRZB ITGA1	3.46e-06	187	55	5	15d6e158562d7d85af3ceaf955439b379c8fce81
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TINAGL1 KCNQ5 SYNE1 FRZB ITGA1	3.46e-06	187	55	5	f62074b631fd45ad299c69d71b09267b04d656ee
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TINAGL1 KCNQ5 SYNE1 FRZB ITGA1	3.55e-06	188	55	5	32f22a4d8cb98fd8b8fa0fbf28ef9266d711d081
ToppCell	Children_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TINAGL1 FAT4 SYNE1 ITGA1 ARHGEF15	3.73e-06	190	55	5	0e9847d7f49b2236b8a191e1a7df37556351ba9e
ToppCell	droplet-Lung-LUNG-30m-Endothelial-endothelial_cell_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TINAGL1 ACKR3 SYNE1 ITGA1 ARHGEF15	3.73e-06	190	55	5	e64b191f928935484e2c993d7f8af0572a617a3a
ToppCell	3'_v3-blood-Myeloid_Monocytic-Nonclassical_monocytes\|blood / Manually curated celltypes from each tissue	HLA-DQB1 ACKR3 FTH1 MRPS35 IL3RA	3.83e-06	191	55	5	44a797b39254cbfa5c2bad8155436adfd3019bb0
ToppCell	Children_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TINAGL1 FAT4 SYNE1 ITGA1 ARHGEF15	3.83e-06	191	55	5	f229abf69a1217194f74b0502486907e07dba989
ToppCell	Control-Endothelial-VE_Capillary_B\|Control / Disease state, Lineage and Cell class	TINAGL1 FAT4 SYNE1 ITGA1 ARHGEF15	3.83e-06	191	55	5	322237793a1278bafb14e63cab688b353e352dcc
ToppCell	droplet-Pancreas-PANCREAS-30m-Endothelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TINAGL1 FAT4 ACKR3 ITGA1 ARHGEF15	3.93e-06	192	55	5	f4cd65e6c5b17bcabf45fe5b687246c72e7975f7
ToppCell	droplet-Pancreas-PANCREAS-30m-Endothelial-endothelial_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TINAGL1 FAT4 ACKR3 ITGA1 ARHGEF15	3.93e-06	192	55	5	bcd8876235be503186f119653b39476488c0fa15
ToppCell	ILEUM-inflamed-(7)_Endothelial_cell-(7)_Lymphatics\|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	DOCK5 EFHC1 ACKR3 KIF3C PKHD1L1	3.93e-06	192	55	5	d43caf42ec744e895137f31ef65a990e250669d2
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	DOCK5 BCL2L11 SYNE1 ITM2C ITGA1	4.13e-06	194	55	5	64535db0420e53e4d777d2333b5051e63e8a3373
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	DOCK5 BCL2L11 SYNE1 ITM2C ITGA1	4.13e-06	194	55	5	b0a7f5ca0c6f4f5764a8b35b5de80d82b828c66c
ToppCell	facs-Heart-LA-3m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TINAGL1 ACKR3 ITGA1 PKHD1L1 ARHGEF15	4.13e-06	194	55	5	33cc4f1d716cb71d54cdedbe9bbdc0d7b17c4777
ToppCell	367C-Myeloid-Macrophage\|367C / Donor, Lineage, Cell class and subclass (all cells)	PTPN6 HLA-DQB1 FTH1 RENBP IL3RA	4.24e-06	195	55	5	77cd831a5da5ab1751499db541f318faf925e527
ToppCell	Severe-CD8+_T_activated\|Severe / Disease group and Cell class	DOCK5 BCL2L11 HLA-DQB1 ITM2C ITGA1	4.45e-06	197	55	5	bb1e3e1d841c2c7141eb1099e7755860b168b6fc
ToppCell	Severe-CD8+_T_activated\|World / Disease group and Cell class	DOCK5 BCL2L11 HLA-DQB1 ITM2C ITGA1	4.57e-06	198	55	5	5ff98c9b6c8c6863767b76c7745f263568f86acc
ToppCell	Biopsy_Control_(H.)-Immune-Macrophages\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	PTPN6 HLA-DQB1 FTH1 RENBP IL3RA	4.79e-06	200	55	5	ad4c23e51bd34f5c515ce759a373ea431368a16e
ToppCell	COVID-19-kidney-Lymphatic_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DOCK5 ACKR3 ITGA1 PKHD1L1	3.37e-05	148	55	4	f777aa1674e898e2594b2b7c029d3d05dda04df9
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4/8-lo-Trm_Tgd\|lymph-node_spleen / Manually curated celltypes from each tissue	DOCK5 EFHC1 ITGA1 NUP205	4.03e-05	155	55	4	b0e456c4915076e1d38282e116a6eb3230ae80dc
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KCNQ5 SYNE1 PKHD1L1 ARHGEF15	4.45e-05	159	55	4	d3f81ba22160568ccaa6d2b04ebfd30630f9a6db
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	BCL2L11 HLA-DQB1 ITM2C SNX9	5.14e-05	165	55	4	83095377aedf960c05baa523869bdbd2b0a05f2d
ToppCell	COVID-19-kidney-Lymphatic_EC\|kidney / Disease (COVID-19 only), tissue and cell type	DOCK5 ACKR3 ITGA1 PKHD1L1	5.39e-05	167	55	4	97d0fea1f41c1c00e36d9b5c4c1f0dd85087056f
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KCNQ5 SYNE1 FRZB ITGA1	5.77e-05	170	55	4	876b84740e15399bfff2b9c7f0b80fd759bbdb3f
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KCNQ5 SYNE1 FRZB ITGA1	5.77e-05	170	55	4	1f8738acf439d893880db7e1fdc9b3615ca00c39
ToppCell	390C-Lymphocytic-ILC-ILC-2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	DOCK5 FGF11 ITM2C ITGA1	6.04e-05	172	55	4	84d16cd7f618c94888920680bdc9e7130d73fd75
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Mesenchymal\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FTH1 RABAC1 PKHD1L1 HYDIN	6.18e-05	173	55	4	66f37c1437705734b20601656fa4aa1d92ca30be
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Mesenchymal-nan\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FTH1 RABAC1 PKHD1L1 HYDIN	6.18e-05	173	55	4	649b08a409095592cccf31883be69c754411280d
ToppCell	normal_Lung-T/NK_cells-Exhausted_Tfh\|T/NK_cells / Location, Cell class and cell subclass	PTPN13 KCNQ5 KIF3C SNX9	6.32e-05	174	55	4	e324320b52c904496e26fcecfa179b3431729ec0
ToppCell	Adult-Endothelial-endothelial_cell_of_vein-D231\|Adult / Lineage, Cell type, age group and donor	TINAGL1 FAT4 PKHD1L1 ARHGEF15	6.32e-05	174	55	4	2dd647c4fdf99fd1f7b838efef01baf2cbc3446d
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TINAGL1 SYNE1 FRZB ITGA1	6.46e-05	175	55	4	1b4cefae400bf756d09ece32d3f5c0bd4c6ad73f
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TINAGL1 SYNE1 FRZB ITGA1	6.46e-05	175	55	4	12f5fd83c7710fc0c77406f765d9cbd133433b8b
ToppCell	droplet-Pancreas-Exocrine-18m-Endothelial-endothelial_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TINAGL1 ACKR3 ITGA1 ARHGEF15	6.60e-05	176	55	4	eb63eb2c301e785196ccadac74a2940b2c524c62
ToppCell	droplet-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell-pericyte\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TINAGL1 KCNQ5 FRZB ITGA1	6.60e-05	176	55	4	e2b59a904c5c8f9c88e1e63788e9b6485f22edd0
ToppCell	droplet-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TINAGL1 KCNQ5 FRZB ITGA1	6.60e-05	176	55	4	f931192e3cc65414e2245354f443473696cc7ce8
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-Pericytes-Immature_pericyte\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TINAGL1 CLTCL1 FRZB ITGA1	6.90e-05	178	55	4	e5e4742e35c3d90f82b830d77bdbdc45828c7deb
ToppCell	3'_v3-blood-Lymphocytic_B_plasma-Plasmablasts\|blood / Manually curated celltypes from each tissue	FRZB ASPM ITM2C PKHD1L1	7.05e-05	179	55	4	7d3bd1f9e126a4a9e0a84720a6cc0b3d235e65ee
ToppCell	10x5'-Lung-Lymphocytic_B_plasma-Plasmablasts\|Lung / Manually curated celltypes from each tissue	ASPM ITM2C LMBRD2 PKHD1L1	7.05e-05	179	55	4	3fa75eec3e86fd1797eaa33362257df7f9b2a0bf
ToppCell	COVID-19-Heart-Lymph_EC\|Heart / Disease (COVID-19 only), tissue and cell type	DOCK5 KIF3C ITGA1 PKHD1L1	7.05e-05	179	55	4	411620201a860716a8773b92f50f7b94ef34a586
ToppCell	droplet-Kidney-KIDNEY-30m-Lymphocytic-Epcam____thick_ascending_tube_S_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EFHC1 ASPM KIF3C ATP4A	7.05e-05	179	55	4	4166c4e1a8748a79ac6a11fd0b97c5344be2321b
ToppCell	P28-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	DOCK5 ARHGEF19 FRZB SORCS2	7.21e-05	180	55	4	1e819c5c87704ec6535dfeaae56561895e239d07
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_B-B_plasma-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	NADK2 ASPM ITM2C PKHD1L1	7.21e-05	180	55	4	8e96f8646c002768b272359af485dc0ab57e0ccd
ToppCell	Thalamus-Macroglia\|Thalamus / BrainAtlas - Mouse McCarroll V32	ARHGEF19 TM7SF3 HACL1 TMBIM1	7.36e-05	181	55	4	4f62b63854a4e9fea6e839f0340e78392c66fb0e
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TINAGL1 SYNE1 FRZB ITGA1	7.36e-05	181	55	4	a2058d658f07ab6f0a28d2622f3090b4cde6f763
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-mesothelial_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PTPN13 IQCA1 ASPM PKHD1L1	7.36e-05	181	55	4	65eaa9bc1022bcf0c5f0f92c07a2cbbf11f9b59c
ToppCell	RA-16._Neuronal\|World / Chamber and Cluster_Paper	DOCK5 PTPN13 FTH1 ITM2C	7.36e-05	181	55	4	7d22a43f887e0747f0cb87ba364ff27905ee6eec
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_CCL3+-Alveolar_macrophage_CCL3+_L.1.0.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HLA-DQB1 FTH1 RENBP IL3RA	7.36e-05	181	55	4	a8d4b2340d99734bf9379b467fb481c598b9b4fb
ToppCell	COVID-19-Endothelial_cells-Capillary_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	SYNE1 HERC3 ITGA1 ARHGEF15	7.36e-05	181	55	4	c5f9c92af1384d9089c65afdf41c6feb8345a3ae
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TINAGL1 SYNE1 FRZB ITGA1	7.36e-05	181	55	4	526e858a848470b6d2d5248788004d9735ed3add
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-mesothelial_cell-Mesothelium_(PRG4+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PTPN13 IQCA1 ASPM PKHD1L1	7.36e-05	181	55	4	eaac7d58117eddfff06b25521efc431c1351d592
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_proliferating-Lymphatic_EC_proliferating_L.2.5.4.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ACKR3 ASPM KIF3C PKHD1L1	7.52e-05	182	55	4	f703963b5d1e8c1f95d78807521048553b0792d8
ToppCell	tumor_Lung-Myeloid_cells-CD207+CD1a+_LCs\|tumor_Lung / Location, Cell class and cell subclass	DOCK5 PTPN6 IL22RA2 HLA-DQB1	7.52e-05	182	55	4	243779ba1009097f8fafa1a691e296ec3aeefc04
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Pericyte-A\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TINAGL1 ADORA2B FRZB ITGA1	7.52e-05	182	55	4	fc4a5bf784705efe7965ce43ac23c2a8e602e90a
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.4.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PTPN6 HLA-DQB1 ACKR3 FTH1	7.52e-05	182	55	4	84f4322ec3d12cb217009f9215af01ebfabc82b4
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_proliferating\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ACKR3 ASPM KIF3C PKHD1L1	7.52e-05	182	55	4	ebd177ad5eac51bf2db0657596618bdf1e5d46e1
ToppCell	facs-Lung-nan-3m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TINAGL1 FRZB TM7SF3 PKHD1L1	7.68e-05	183	55	4	12e876d6205af8aad74265c668b5e95b9e7487f3
ToppCell	facs-Pancreas-Exocrine-18m-Endothelial-endothelial_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TINAGL1 ACKR3 ITGA1 ARHGEF15	7.68e-05	183	55	4	c9d9d7dd629ce6787502103b158a07e8684a66f8
ToppCell	ILEUM-inflamed-(5)_IgA_plasma_cells\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	BCL2L11 RABAC1 ITM2C PKHD1L1	7.68e-05	183	55	4	a113558ca4220bac31f9336033dff82a618d9258
ToppCell	facs-Pancreas-Exocrine-18m-Endothelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TINAGL1 ACKR3 ITGA1 ARHGEF15	7.68e-05	183	55	4	c7ef8ee2b3fcfa69cea0fdcb2041674b832933db
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_CCL3+-Alveolar_macrophage_CCL3+_L.1.0.2.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HLA-DQB1 FTH1 RENBP IL3RA	7.68e-05	183	55	4	02deb595819fb864a934fd0fcaad684f1ca42964
ToppCell	facs-Pancreas-Exocrine-18m-Endothelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TINAGL1 ACKR3 ITGA1 ARHGEF15	7.68e-05	183	55	4	92eee4bdd84965ae0bd1ed1c7f26a3b83ad0cdac
ToppCell	facs-Pancreas-Endocrine-24m-Endothelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TINAGL1 ACKR3 ITGA1 ARHGEF15	8.01e-05	185	55	4	7f9121bbff3471982aa8706a599922c2d28e6e9b
ToppCell	facs-Pancreas-Endocrine-24m-Endothelial-endothelial_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TINAGL1 ACKR3 ITGA1 ARHGEF15	8.01e-05	185	55	4	8159e0aef2c8826e0deac6fdc90505ac0400ba2b
ToppCell	facs-Pancreas-Endocrine-24m-Endothelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TINAGL1 ACKR3 ITGA1 ARHGEF15	8.01e-05	185	55	4	8626fb015cfa20c847661b74ef51ca0dfd1025e0
ToppCell	10x5'-bone_marrow-Myeloid_Dendritic-Cycling_Dendritic\|bone_marrow / Manually curated celltypes from each tissue	TINAGL1 ASPM ITM2C IL3RA	8.01e-05	185	55	4	9d3168c7f0b1d739f78b368969cf5c77ce202b97
ToppCell	nucseq-Mesenchymal-Myocytic-Myocytic_2-VSMC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	TINAGL1 FRZB ITM2C ITGA1	8.18e-05	186	55	4	c7885fd6dc7dc8fffc96f0112c51a365cf8a8f80
ToppCell	COPD-Stromal-Pericyte\|World / Disease state, Lineage and Cell class	TINAGL1 FRZB ITM2C ITGA1	8.18e-05	186	55	4	8adfd2d1fda4e8aecc95192ea627bf7ed5214b8d
ToppCell	COVID-19-lung-Plasmablasts\|lung / Disease (COVID-19 only), tissue and cell type	KCNQ5 ASPM RABAC1 ITM2C	8.18e-05	186	55	4	81caf67da9fed09c77b7ddcab9b0b8e4fab2de97
ToppCell	droplet-Heart-nan-3m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TINAGL1 ITGA1 PKHD1L1 ARHGEF15	8.18e-05	186	55	4	0ae5fbe9f210cb25092394267e1d3d6ed05627b8
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TINAGL1 SYNE1 FRZB ITGA1	8.35e-05	187	55	4	d591a3c216997663ab77710fed0d230ffc37e41a
ToppCell	lymphoid-B_cell-Naive_B_cell\|World / Lineage, cell class and subclass	HLA-DQB1 ITM2C SNX9 PKHD1L1	8.35e-05	187	55	4	904ffd8cf4513e86fcd4c2b7faf24a34fbd2dce3
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TINAGL1 SYNE1 FRZB ITGA1	8.35e-05	187	55	4	d1dc8c9a2c2cd10c640257161a75e7730ec5bb41
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TINAGL1 SYNE1 FRZB ITGA1	8.35e-05	187	55	4	ac8e092b37e042975e2ee057d3f7c6821e58e8b5
ToppCell	normal_Lung-Myeloid_cells-pDCs\|Myeloid_cells / Location, Cell class and cell subclass	KCNQ5 ZFP30 ITM2C IL3RA	8.35e-05	187	55	4	a3592f056e1c2f82ba325fea2ecc4dd6c6347c81
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	DOCK5 BCL2L11 ITM2C ITGA1	8.35e-05	187	55	4	d17352f769c3c66601b65d060626eecff41b0482
ToppCell	normal_Lung-Myeloid_cells-pDCs\|normal_Lung / Location, Cell class and cell subclass	KCNQ5 ZFP30 ITM2C IL3RA	8.35e-05	187	55	4	d36751372fd40a46441f07735c9c3c5dcb503f24
ToppCell	lymphoid-B_cell\|World / Lineage, cell class and subclass	HLA-DQB1 ITM2C SNX9 PKHD1L1	8.35e-05	187	55	4	2abbc01fd7f5b4e52113699625287893c991f8da
ToppCell	droplet-Liver-LIVER_NPC-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TINAGL1 FAT4 ITGA1 ARHGEF15	8.52e-05	188	55	4	0aa8747c2931b0c91f6d78bb2db8fd8ede6dd559
ToppCell	11.5-Airway-Mesenchymal-Pericyte\|Airway / Age, Tissue, Lineage and Cell class	TINAGL1 KCNQ5 FRZB ITGA1	8.52e-05	188	55	4	916971d8660fd20f616346953874e89d2cd13e88
ToppCell	15-Distal-Mesenchymal-Pericyte\|Distal / Age, Tissue, Lineage and Cell class	TINAGL1 KCNQ5 FRZB ITGA1	8.52e-05	188	55	4	4963382e54aac06bf5047c7d725393db70667ee7
ToppCell	10x5'v1-week_12-13-Myeloid_neutrophil-granulo-eo/baso/mast-basophil\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	FTH1 RENBP IL3RA TMBIM1	8.52e-05	188	55	4	b4d695c373195d389e0a579e9589e87433286b24
ToppCell	background-B_cells\|background / Sample and Cell Type and Tumor Cluster (all cells)	KCNQ5 ITM2C IL3RA FCHO1	8.52e-05	188	55	4	9acb7a95e3095f15918a5d094107d1d565a42842
ToppCell	ASK428-Endothelial-Lymphatic\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	FAT4 KIF3C ITGA1 PKHD1L1	8.52e-05	188	55	4	c371bc340966cfe9205cbf4b62c6452f49f2559f
ToppCell	COVID-19-lung-Lymphatic_EC\|lung / Disease (COVID-19 only), tissue and cell type	DOCK5 ACKR3 KIF3C PKHD1L1	8.70e-05	189	55	4	c8db9aaf54ea3cc96c4a2f777c3389e0f31f67f3
ToppCell	368C-Myeloid-Macrophage\|368C / Donor, Lineage, Cell class and subclass (all cells)	PTPN6 HLA-DQB1 RENBP IL3RA	8.70e-05	189	55	4	e62355be0d136e2b7c739848022292e9c6af7392
ToppCell	COVID-19-Heart-EC_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TINAGL1 SYNE1 ITGA1 ARHGEF15	8.70e-05	189	55	4	fe49852ba15f948b384d6b4c258927c70b741357
ToppCell	droplet-Lung-LUNG-30m-Endothelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TINAGL1 ACKR3 ITGA1 ARHGEF15	8.70e-05	189	55	4	25db316f66cee53774bb2b286cc457b37353356c
ToppCell	ILEUM-inflamed-(5)_IgM_plasma_cells\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	BCL2L11 RABAC1 ITM2C PKHD1L1	8.70e-05	189	55	4	fa9387d120cde6416998234c6ebd0ef74deed768
ToppCell	COVID-19-lung-Plasmablasts\|COVID-19 / Disease (COVID-19 only), tissue and cell type	KCNQ5 ASPM RABAC1 ITM2C	8.70e-05	189	55	4	fdf6c945b352614885e646a5ef4bc576dee73895
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	EFHC1 KIF3B BEST4 HYDIN	8.70e-05	189	55	4	b4b93bd10b7e3cc16e54ff73beac230f519c010a
ToppCell	droplet-Pancreas-PANCREAS-30m-Endothelial-endothelial_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TINAGL1 ACKR3 ITGA1 ARHGEF15	8.88e-05	190	55	4	9d5242759546be0089981ef1877e4ed5f81face5
ToppCell	Nasal_Brush-Epithelial-Ciliated_2\|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	EFHC1 SYNE1 BEST4 HYDIN	8.88e-05	190	55	4	9ce7df056bfb24d70db4c3c4a2c57d89115de877
ToppCell	Nasal_Brush-Epithelial-Ciliated_2\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	EFHC1 SYNE1 BEST4 HYDIN	8.88e-05	190	55	4	833481ace2800354712e2ce709d5cdfd0aed3d42
ToppCell	facs-Pancreas-Exocrine-3m-Endothelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TINAGL1 ACKR3 ITGA1 ARHGEF15	8.88e-05	190	55	4	b7fc451e160e31dc898b122de844b501f587db67
ToppCell	Children_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TINAGL1 SYNE1 ITGA1 ARHGEF15	8.88e-05	190	55	4	0a351609a72fd638c84b2435782e312ee6a33aac
ToppCell	normal_Lymph_Node-B_lymphocytes-MALT_B_cells\|normal_Lymph_Node / Location, Cell class and cell subclass	FRZB RABAC1 ITM2C PKHD1L1	8.88e-05	190	55	4	1f907016980ccfbf089e354d91d931771e8a83e0
ToppCell	droplet-Marrow-nan-21m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADORA2B ITM2C ITGA1 IL3RA	8.88e-05	190	55	4	6c6d3259e23ec90c08756f500ae8a7aff8b8a5b3
Disease	alanine measurement	CLTCL1 NADK2 MIPEP ITGA1	2.05e-05	86	55	4	EFO_0009765
Disease	aspirin-induced respiratory disease (is_implicated_in)	HLA-DQB1 HLA-DRB4	1.86e-04	11	55	2	DOID:0080822 (is_implicated_in)
Disease	serum gamma-glutamyl transferase measurement	ARHGEF19 SLC9A4 DYRK1A ITGA1 SNX9 FCHO1 ARHGEF15 KLC1	2.76e-04	914	55	8	EFO_0004532
Disease	non-high density lipoprotein cholesterol measurement	HLA-DQB1 SORCS2 ITM2C ITGA1 HYDIN TMBIM1 ARHGEF15	3.46e-04	713	55	7	EFO_0005689
Disease	neutrophil count	EFHC1 BCL2L11 HLA-DQB1 ACKR3 MIPEP DYRK1A ITM2C FCHO1 HYDIN	9.59e-04	1382	55	9	EFO_0004833
Disease	Hodgkins lymphoma, multiple myeloma, non-Hodgkins lymphoma	BCL2L11 HLA-DQB1	1.25e-03	28	55	2	EFO_0000183, EFO_0001378, EFO_0005952
Disease	forced expiratory volume, response to bronchodilator	DOCK5 ACKR3 SYNE1 HERC3 NUP205	1.43e-03	445	55	5	EFO_0004314, GO_0097366
Disease	fear of minor pain measurement	DOCK5 IQCA1	1.53e-03	31	55	2	EFO_0008340

Protein segments in the cluster

Peptide	Gene	Start	Entry
QEQRYVYAQVARYCN	BEST4	56	Q8NFU0
NPIVYAYRNRDFRYT	ADORA2B	286	P29275
YYRIVARYENTLAAQ	SMPD1	441	P17405
YEVQQYYILTVRAED	FAT4	1906	Q6V0I7
AYYARRVFLNNYQAA	BCL2L11	161	O43521
VYVDYVRNQQYQEET	ARHGEF15	506	O94989
QRIYQYIQSRFYRSP	DYRK1A	316	Q13627
YVKYVQIFRNLENVY	IQCA1	46	Q86XH1
IQSNYRRYRQQTYFN	ASPM	2196	Q8IZT6
NYYTVFYHVQEQLPR	HACL1	376	Q9UJ83
YFYQEEFYIRRVHNL	NUP205	381	Q92621
AFRRVYLPYVTNQAY	ARHGEF19	461	Q8IW93
ASYYNVVLLRYQFSR	FCHO1	731	O14526
LRLFYQVAEYTFRQF	RENBP	346	P51606
RRNVAVYYVSYAVFV	TMBIM1	131	Q969X1
KTTRYEFEQQRYRYA	NADK2	76	Q4G0N4
RQEFVDAYVNYVFQI	HERC3	886	Q15034
VKYRRVQNYLYNVLE	KCNQ5	106	Q9NR82
NQQYLVRASYLEIYQ	KIF3C	136	O14782
EDYYELLYRVFIINN	IL22RA2	196	Q969J5
VYVYALNQTRFEYQM	ITGA1	526	P56199
SVYIYRYFFLAQLAR	ITM2C	76	Q9NQX7
ENYYVLYASALYRQR	FGF11	151	Q92914
INRQINLELYASYVY	FTH1	21	P02794
VRYVTRYIYNREEYA	HLA-DQB1	56	P01920
YDLYLNVANRRQQYE	IL3RA	136	P26951
IFRNEVTNEFLYYNV	HYDIN	4811	Q4G0P3
VKFINYTRQRTEYYC	HYDIN	4946	Q4G0P3
LVIYYLRQDDVQEAY	TTC26	291	A0AVF1
FYRYSRQLRYEVDQA	KLHL15	241	Q96M94
LNYYRANEVQQFRYS	DOCK5	1451	Q9H7D0
NPVLYSFINRNYRYE	ACKR3	311	P25106
LIRYIYNQEEYARYN	HLA-DRB4	56	P13762
IICYYNTYQVVQFNR	LAMTOR3	71	Q9UHA4
TEEQYRIRQVNIYYY	EFHC1	111	Q5JVL4
VYQQVYRPVYFQLVD	IPO13	381	O94829
QRLYQQYTCYTVFFI	ATP4A	921	P20648
NRQINLELYASYVYL	FTMT	81	Q8N4E7
EEVEYYYQRALEIYQ	KLC1	356	Q07866
QYIFCYQVILYVLTR	PTPN13	2456	Q12923
RQNYDYAVYLLTVLY	MRPS35	216	P82673
YDYNSVIRLYLEQQV	SNX9	561	Q9Y5X1
YVNNNDIYQVTPVYR	TINAGL1	331	Q9GZM7
IYSQCQRYYQVFQAA	SYNE1	4991	Q8NF91
TVFRIRVFNYYYLAS	LMBRD2	451	Q68DH5
KNYYTAFLSIRVRQY	NICN1	51	Q9BSH3
ANQTKYYVSYRRNEF	SORCS2	361	Q96PQ0
YQVRQRTLSYNKYNL	SLC9A4	601	Q6AI14
LYRNNLQRYIEIYVQ	CLTCL1	791	P53675
YQRNLYRDVILENYS	ZFP30	26	Q9Y2G7
EYFANDYRVVNQFAR	MIPEP	531	Q99797
TQKTYFRNNYNYVIR	FRZB	186	Q92765
QQYLVRASYLEIYQE	KIF3B	136	O15066
VGLYQYRNVYTEQQT	PKHD1L1	476	Q86WI1
RLVRNVEYYQSNYVF	RABAC1	66	Q9UI14
FVYLRQPYYATRVNA	PTPN6	206	P29350
LFRFYLVYTIQTNRN	WDR91	91	A4D1P6
QDSRWRLQYDVYQYF	TM7SF3	186	Q9NS93