Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionDNA photolyase activity

CRY2 CRY1

2.15e-052932GO:0003913
GeneOntologyMolecularFunctionDNA (6-4) photolyase activity

CRY2 CRY1

2.15e-052932GO:0003914
GeneOntologyMolecularFunctiondeoxyribodipyrimidine photo-lyase activity

CRY2 CRY1

2.15e-052932GO:0003904
GeneOntologyMolecularFunctionblue light photoreceptor activity

CRY2 CRY1

2.15e-052932GO:0009882
GeneOntologyMolecularFunctionferroxidase activity

CP HEPHL1

3.18e-046932GO:0004322
GeneOntologyMolecularFunctionoxidoreductase activity, acting on metal ions, oxygen as acceptor

CP HEPHL1

3.18e-046932GO:0016724
GeneOntologyMolecularFunctionTAP complex binding

HLA-E HLA-F

7.56e-049932GO:0062061
GeneOntologyMolecularFunctionCD8 receptor binding

HLA-E HLA-F

7.56e-049932GO:0042610
GeneOntologyMolecularFunctionTAP1 binding

HLA-E HLA-F

9.42e-0410932GO:0046978
GeneOntologyMolecularFunctionTAP2 binding

HLA-E HLA-F

9.42e-0410932GO:0046979
GeneOntologyMolecularFunctionTAP binding

HLA-E HLA-F

9.42e-0410932GO:0046977
GeneOntologyMolecularFunctionfrizzled binding

ZNRF3 WNT2B RNF43

9.84e-0442933GO:0005109
GeneOntologyMolecularFunctionFAD binding

CRY2 MICAL1 CRY1

1.13e-0344933GO:0071949
GeneOntologyMolecularFunctionbeta-2-microglobulin binding

HLA-E HLA-F

1.37e-0312932GO:0030881
GeneOntologyMolecularFunctionubiquitin-protein transferase activity

FBXO9 TRIM51 ZNRF3 TRIM49D1 RNF43 RNF133 TRIM48 TRIM51G

1.64e-03473938GO:0004842
GeneOntologyMolecularFunctionubiquitin protein ligase activity

TRIM51 ZNRF3 TRIM49D1 RNF43 RNF133 TRIM48 TRIM51G

1.77e-03372937GO:0061630
GeneOntologyMolecularFunction3'-5' DNA helicase activity

RECQL4 NAV2

2.47e-0316932GO:0043138
GeneOntologyMolecularFunctionubiquitin-like protein ligase activity

TRIM51 ZNRF3 TRIM49D1 RNF43 RNF133 TRIM48 TRIM51G

2.58e-03398937GO:0061659
GeneOntologyMolecularFunctionubiquitin-like protein transferase activity

FBXO9 TRIM51 ZNRF3 TRIM49D1 RNF43 RNF133 TRIM48 TRIM51G

2.68e-03512938GO:0019787
GeneOntologyMolecularFunctionnatural killer cell lectin-like receptor binding

HLA-E HLA-F

2.79e-0317932GO:0046703
GeneOntologyMolecularFunctionphotoreceptor activity

CRY2 CRY1

2.79e-0317932GO:0009881
GeneOntologyBiologicalProcessblue light signaling pathway

CRY2 CRY1

2.05e-052942GO:0009785
GeneOntologyBiologicalProcesscellular response to blue light

CRY2 CRY1

2.05e-052942GO:0071483
GeneOntologyBiologicalProcessWnt receptor catabolic process

ZNRF3 RNF43

2.05e-052942GO:0038018
GeneOntologyBiologicalProcessantigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway

HLA-E HLA-F

1.23e-044942GO:0002488
GeneOntologyBiologicalProcessantigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent

HLA-E HLA-F

1.23e-044942GO:0002489
GeneOntologyBiologicalProcessantigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent

HLA-E HLA-F

2.04e-045942GO:0002481
GeneOntologyBiologicalProcessantigen processing and presentation of exogenous peptide antigen via MHC class Ib

HLA-E HLA-F

2.04e-045942GO:0002477
GeneOntologyBiologicalProcessnegative regulation of corticosteroid hormone secretion

CRY2 CRY1

2.04e-045942GO:2000847
GeneOntologyBiologicalProcessnegative regulation of steroid hormone secretion

CRY2 CRY1

2.04e-045942GO:2000832
GeneOntologyBiologicalProcessnegative regulation of glucocorticoid secretion

CRY2 CRY1

2.04e-045942GO:2000850
GeneOntologyCellularComponentpostsynaptic specialization membrane

GPHN SORCS2 DGKI LRRC4B LRRC4C LRRC4

2.63e-04201926GO:0099634
GeneOntologyCellularComponentMHC class Ib protein complex

HLA-E HLA-F

3.97e-047922GO:0032398
GeneOntologyCellularComponentpostsynaptic density membrane

SORCS2 DGKI LRRC4B LRRC4C LRRC4

6.52e-04157925GO:0098839
GeneOntologyCellularComponentMHC class I protein complex

HLA-E HLA-F

8.43e-0410922GO:0042612
GeneOntologyCellularComponentpostsynaptic density

GPHN ABI3BP CAMK2G SORCS2 DGKI LRRC4B LRRC4C LRRC4

8.44e-04451928GO:0014069
GeneOntologyCellularComponentendosome lumen

NAPSA LGMN AP4M1

8.96e-0443923GO:0031904
GeneOntologyCellularComponentasymmetric synapse

GPHN ABI3BP CAMK2G SORCS2 DGKI LRRC4B LRRC4C LRRC4

1.21e-03477928GO:0032279
GeneOntologyCellularComponentMHC class I peptide loading complex

HLA-E HLA-F

1.68e-0314922GO:0042824
GeneOntologyCellularComponentpostsynaptic specialization

GPHN ABI3BP CAMK2G SORCS2 DGKI LRRC4B LRRC4C LRRC4

1.69e-03503928GO:0099572
MousePhenoabnormal macrophage nitric oxide production

HLA-E HLA-F CCR1

2.65e-0513653MP:0011074
DomainDNA_photolyase

CRY2 CRY1

2.51e-052942PF00875
DomainDNA_photolyase_N

CRY2 CRY1

2.51e-052942IPR006050
DomainFAD_binding_7

CRY2 CRY1

2.51e-052942PF03441
DomainCryptochr/Photolyase_FAD-bd

CRY2 CRY1

2.51e-052942IPR005101
DomainPHR_CRY_ALPHA_BETA

CRY2 CRY1

2.51e-052942PS51645
DomainMULTICOPPER_OXIDASE2

CP HEPHL1

7.49e-053942PS00080
DomainConA-like_dom

MEP1B TRIM16 TRIM51 SLIT1 TRIM49D1 ADGRG4 ADGRD1

1.19e-04219947IPR013320
DomainLRRNT

SLIT1 LRRC4B LRRC4C LRRC4

1.46e-0453944PF01462
DomainCu-oxidase_2

CP HEPHL1

1.49e-044942IPR011706
DomainCu-oxidase_2

CP HEPHL1

1.49e-044942PF07731
DomainCu_oxidase_CS

CP HEPHL1

2.48e-045942IPR033138
DomainCu-oxidase_3

CP HEPHL1

2.48e-045942IPR011707
DomainMULTICOPPER_OXIDASE1

CP HEPHL1

2.48e-045942PS00079
DomainCu-oxidase_3

CP HEPHL1

2.48e-045942PF07732
DomainMHC_I_a_C

HLA-E HLA-F

3.71e-046942IPR010579
DomainMHC_I_C

HLA-E HLA-F

3.71e-046942PF06623
DomainCu_oxidase_Cu_BS

CP HEPHL1

3.71e-046942IPR002355
DomainBBOX

TRIM16 TRIM51 TRIM49D1 TRIM48

4.05e-0469944SM00336
DomainButyrophylin

TRIM16 TRIM51 TRIM49D1 TRIM48

4.28e-0470944IPR003879
Domain-

TRIM16 TRIM51 TRIM49D1 TRIM48

4.52e-04719444.10.45.10
Domainzf-B_box

TRIM16 TRIM51 TRIM49D1 TRIM48

4.76e-0472944PF00643
DomainZF_BBOX

TRIM16 TRIM51 TRIM49D1 TRIM48

7.10e-0480944PS50119
DomainZnf_B-box

TRIM16 TRIM51 TRIM49D1 TRIM48

7.44e-0481944IPR000315
DomainCys-rich_flank_reg_C

SLIT1 LRRC4B LRRC4C LRRC4

1.10e-0390944IPR000483
DomainLRRCT

SLIT1 LRRC4B LRRC4C LRRC4

1.10e-0390944SM00082
DomainSPRY

TRIM16 TRIM51 TRIM49D1 TRIM48

1.30e-0394944PF00622
DomainSPRY_dom

TRIM16 TRIM51 TRIM49D1 TRIM48

1.30e-0394944IPR003877
DomainB30.2/SPRY

TRIM16 TRIM51 TRIM49D1 TRIM48

1.35e-0395944IPR001870
DomainB302_SPRY

TRIM16 TRIM51 TRIM49D1 TRIM48

1.35e-0395944PS50188
DomainLRRNT

SLIT1 LRRC4B LRRC4C LRRC4

1.51e-0398944IPR000372
DomainLRRNT

SLIT1 LRRC4B LRRC4C LRRC4

1.51e-0398944SM00013
DomainZnf_C3HC4_RING-type

TRIM51 ZNRF3 RNF43 RNF133 TRIM48

1.77e-03172945IPR018957
Domain-

CP HEPHL1

2.19e-03149422.60.40.420
Domainzf-RING_2

ZNRF3 RNF43 RNF133

2.28e-0352943PF13639
DomainIg_I-set

IGFN1 LRRC4B LRRC4C LRRC4 UNC5D

2.73e-03190945IPR013098
DomainI-set

IGFN1 LRRC4B LRRC4C LRRC4 UNC5D

2.73e-03190945PF07679
DomainZF_RING_2

TRIM51 ZNRF3 TRIM49D1 RNF43 RNF133 TRIM48

3.95e-03298946PS50089
DomainCH

MICAL1 NAV3 NAV2

4.30e-0365943SM00033
DomainRING

TRIM51 ZNRF3 TRIM49D1 RNF43 RNF133 TRIM48

4.42e-03305946SM00184
DomainF-box

FBXO9 FBXO46 FBXO34

4.69e-0367943PF00646
DomainMHC_I

HLA-E HLA-F

4.95e-0321942PF00129
DomainMHC_I_a_a1/a2

HLA-E HLA-F

4.95e-0321942IPR001039
Pubmed

NGL family PSD-95-interacting adhesion molecules regulate excitatory synapse formation.

LRRC4B LRRC4C LRRC4

4.40e-061296316980967
Pubmed

SCFFbxl3 controls the oscillation of the circadian clock by directing the degradation of cryptochrome proteins.

CRY2 FBXO9 CRY1

7.26e-061496317463251
Pubmed

E3 ligases RNF43 and ZNRF3 display differential specificity for endocytosis of Frizzled receptors.

ZNRF3 RNF43

7.54e-06296238969364
Pubmed

RNF43 and ZNRF3 are commonly altered in serrated pathway colorectal tumorigenesis.

ZNRF3 RNF43

7.54e-06296227661107
Pubmed

Delay in feedback repression by cryptochrome 1 is required for circadian clock function.

CRY2 CRY1

7.54e-06296221236481
Pubmed

CRY1, CRY2 and PRKCDBP genetic variants in metabolic syndrome.

CRY2 CRY1

7.54e-06296225391456
Pubmed

Loss of circadian rhythm and light-induced suppression of pineal melatonin levels in Cry1 and Cry2 double-deficient mice.

CRY2 CRY1

7.54e-06296220825493
Pubmed

The ratio of intracellular CRY proteins determines the clock period length.

CRY2 CRY1

7.54e-06296226966073
Pubmed

Cognitive dysfunction, elevated anxiety, and reduced cocaine response in circadian clock-deficient cryptochrome knockout mice.

CRY2 CRY1

7.54e-06296224187535
Pubmed

The circadian clock components CRY1 and CRY2 are necessary to sustain sex dimorphism in mouse liver metabolism.

CRY2 CRY1

7.54e-06296219211562
Pubmed

Clock Regulation of Metabolites Reveals Coupling between Transcription and Metabolism.

CRY2 CRY1

7.54e-06296228380384
Pubmed

The expression of clock genes cry1 and cry2 in human colorectal cancer and tumor adjacent tissues correlates differently dependent on tumor location.

CRY2 CRY1

7.54e-06296229940771
Pubmed

Mice deficient in cryptochrome 1 (cry1 (-/-)) exhibit resistance to obesity induced by a high-fat diet.

CRY2 CRY1

7.54e-06296224782829
Pubmed

Redox potential: differential roles in dCRY and mCRY1 functions.

CRY2 CRY1

7.54e-06296211818067
Pubmed

Circadian oscillation of nucleotide excision repair in mammalian brain.

CRY2 CRY1

7.54e-06296219164551
Pubmed

Differential regulation of mammalian period genes and circadian rhythmicity by cryptochromes 1 and 2.

CRY2 CRY1

7.54e-06296210518585
Pubmed

Circadian intraocular pressure rhythm is generated by clock genes.

CRY2 CRY1

7.54e-06296216936122
Pubmed

Mammalian Cry1 and Cry2 are essential for maintenance of circadian rhythms.

CRY2 CRY1

7.54e-06296210217146
Pubmed

Pleiotropic effects of cryptochromes 1 and 2 on free-running and light-entrained murine circadian rhythms.

CRY2 CRY1

7.54e-06296212696673
Pubmed

Analysis of autophosphorylating kinase activities of Arabidopsis and human cryptochromes.

CRY2 CRY1

7.54e-06296217073458
Pubmed

Mammalian cryptochromes impinge on cell cycle progression in a circadian clock-independent manner.

CRY2 CRY1

7.54e-06296222033214
Pubmed

Sleep deprivation effects on circadian clock gene expression in the cerebral cortex parallel electroencephalographic differences among mouse strains.

CRY2 CRY1

7.54e-06296218614689
Pubmed

Characterization of photolyase/blue-light receptor homologs in mouse and human cells.

CRY2 CRY1

7.54e-0629629801304
Pubmed

Synchronization of cellular clocks in the suprachiasmatic nucleus.

CRY2 CRY1

7.54e-06296214631044
Pubmed

Autonomic and cardiovascular responses to scent stimulation are altered in cry KO mice.

CRY2 CRY1

7.54e-06296217175102
Pubmed

Measurement of internal body time by blood metabolomics.

CRY2 CRY1

7.54e-06296219487679
Pubmed

Further characterization of the phenotype of mCry1/mCry2-deficient mice.

CRY2 CRY1

7.54e-06296211587085
Pubmed

Cancer, hear my battle CRY.

CRY2 CRY1

7.54e-06296232291799
Pubmed

Suppression of circadian clock protein cryptochrome 2 promotes osteoarthritis.

CRY2 CRY1

7.54e-06296232339698
Pubmed

Identification of zyklopen, a new member of the vertebrate multicopper ferroxidase family, and characterization in rodents and human cells.

CP HEPHL1

7.54e-06296220685892
Pubmed

Putative human blue-light photoreceptors hCRY1 and hCRY2 are flavoproteins.

CRY2 CRY1

7.54e-0629628909283
Pubmed

NGL-3 in the regulation of brain development, Akt/GSK3b signaling, long-term depression, and locomotive and cognitive behaviors.

LRRC4B LRRC4C

7.54e-06296231166939
Pubmed

CRY1 and CRY2 genetic variants in seasonality: A longitudinal and cross-sectional study.

CRY2 CRY1

7.54e-06296227267441
Pubmed

Vagal regulation of respiratory clocks in mice.

CRY2 CRY1

7.54e-06296217442820
Pubmed

Circadian rhythm of RNA N6-methyladenosine and the role of cryptochrome.

CRY2 CRY1

7.54e-06296226239657
Pubmed

Altered food-anticipatory activity rhythm in Cryptochrome-deficient mice.

CRY2 CRY1

7.54e-06296215893577
Pubmed

ZNRF3 and RNF43 cooperate to safeguard metabolic liver zonation and hepatocyte proliferation.

ZNRF3 RNF43

7.54e-06296234129813
Pubmed

Circadian behavioral rhythms in Cry1/Cry2 double-deficient mice induced by methamphetamine.

CRY2 CRY1

7.54e-06296218258761
Pubmed

RNF43/ZNRF3 loss predisposes to hepatocellular-carcinoma by impairing liver regeneration and altering the liver lipid metabolic ground-state.

ZNRF3 RNF43

7.54e-06296235039505
Pubmed

The Placental Ferroxidase Zyklopen Is Not Essential for Iron Transport to the Fetus in Mice.

CP HEPHL1

7.54e-06296234114013
Pubmed

Mammalian clock gene Cryptochrome regulates arthritis via proinflammatory cytokine TNF-alpha.

CRY2 CRY1

7.54e-06296220042581
Pubmed

Interval timing is intact in arrhythmic Cry1/Cry2-deficient mice.

CRY2 CRY1

7.54e-06296221775289
Pubmed

Control of skin cancer by the circadian rhythm.

CRY2 CRY1

7.54e-06296222025708
Pubmed

Circadian time-place learning in mice depends on Cry genes.

CRY2 CRY1

7.54e-06296218514517
Pubmed

Altered phase-relationship between peripheral oscillators and environmental time in Cry1 or Cry2 deficient mouse models for early and late chronotypes.

CRY2 CRY1

7.54e-06296224386234
Pubmed

Role of mouse cryptochrome blue-light photoreceptor in circadian photoresponses.

CRY2 CRY1

7.54e-0629629822380
Pubmed

The Potorous CPD photolyase rescues a cryptochrome-deficient mammalian circadian clock.

CRY2 CRY1

7.54e-06296221858120
Pubmed

Serine phosphorylation of mCRY1 and mCRY2 by mitogen-activated protein kinase.

CRY2 CRY1

7.54e-06296215298678
Pubmed

Structural differences in the FAD-binding pockets and lid loops of mammalian CRY1 and CRY2 for isoform-selective regulation.

CRY2 CRY1

7.54e-06296234172584
Pubmed

Cryptochrome-deficient mice lack circadian electrical activity in the suprachiasmatic nuclei.

CRY2 CRY1

7.54e-06296212121621
Pubmed

Expression of the blue-light receptor cryptochrome in the human retina.

CRY2 CRY1

7.54e-06296214507900
Pubmed

Light signalling in cryptochrome-deficient mice.

CRY2 CRY1

7.54e-06296214712914
Pubmed

Circadian clock-dependent and -independent rhythmic proteomes implement distinct diurnal functions in mouse liver.

CRY2 CRY1

7.54e-06296224344304
Pubmed

Postnatal constant light compensates Cryptochrome1 and 2 double deficiency for disruption of circadian behavioral rhythms in mice under constant dark.

CRY2 CRY1

7.54e-06296224278295
Pubmed

High-fat diet-induced hyperinsulinemia and tissue-specific insulin resistance in Cry-deficient mice.

CRY2 CRY1

7.54e-06296223531614
Pubmed

Cryptochrome, circadian cycle, cell cycle checkpoints, and cancer.

CRY2 CRY1

7.54e-06296216061665
Pubmed

Daily variation in the electrophysiological activity of mouse medial habenula neurones.

CRY2 CRY1

7.54e-06296224247982
Pubmed

HLA-E and HLA-F Are Overexpressed in Glioblastoma and HLA-E Increased After Exposure to Ionizing Radiation.

HLA-E HLA-F

7.54e-06296235181585
Pubmed

Deregulated expression of cryptochrome genes in human colorectal cancer.

CRY2 CRY1

7.54e-06296226768731
Pubmed

Network features of the mammalian circadian clock.

CRY2 CRY1

7.54e-06296219278294
Pubmed

Perspectives: neurobiology. The CRYs fo flies and mice.

CRY2 CRY1

7.54e-06296210636810
Pubmed

Photolyase/cryptochrome blue-light photoreceptors use photon energy to repair DNA and reset the circadian clock.

CRY2 CRY1

7.54e-06296212483519
Pubmed

Circadian clock cryptochrome proteins regulate autoimmunity.

CRY2 CRY1

7.54e-06296229109286
Pubmed

Reduced light response of neuronal firing activity in the suprachiasmatic nucleus and optic nerve of cryptochrome-deficient mice.

CRY2 CRY1

7.54e-06296222216107
Pubmed

HLA-F complex without peptide binds to MHC class I protein in the open conformer form.

HLA-E HLA-F

7.54e-06296220483783
Pubmed

Deregulated expression of cry1 and cry2 in human gliomas.

CRY2 CRY1

7.54e-06296223317246
Pubmed

Circadian clock protein cryptochrome regulates the expression of proinflammatory cytokines.

CRY2 CRY1

7.54e-06296222778400
Pubmed

Knockout-Rescue Embryonic Stem Cell-Derived Mouse Reveals Circadian-Period Control by Quality and Quantity of CRY1.

CRY2 CRY1

7.54e-06296228017587
Pubmed

A role for cryptochromes in sleep regulation.

CRY2 CRY1

7.54e-06296212495442
Pubmed

Restoring the Molecular Clockwork within the Suprachiasmatic Hypothalamus of an Otherwise Clockless Mouse Enables Circadian Phasing and Stabilization of Sleep-Wake Cycles and Reverses Memory Deficits.

CRY2 CRY1

7.54e-06296234446572
Pubmed

Human leukocyte antigen (HLA)-E and HLA-F expression in gastric cancer.

HLA-E HLA-F

7.54e-06296225862890
Pubmed

Clock gene defect disrupts light-dependency of autonomic nerve activity.

CRY2 CRY1

7.54e-06296217964540
Pubmed

Time of feeding and the intrinsic circadian clock drive rhythms in hepatic gene expression.

CRY2 CRY1

7.54e-06296219940241
Pubmed

Nuclear Proteomics Uncovers Diurnal Regulatory Landscapes in Mouse Liver.

CRY2 CRY1

7.54e-06296227818260
Pubmed

The involvement of Cry1 and Cry2 genes in the regulation of the circadian body temperature rhythm in mice.

CRY2 CRY1

7.54e-06296215331384
Pubmed

Cryptochromes are critical for the development of coherent circadian rhythms in the mouse suprachiasmatic nucleus.

CRY2 CRY1

7.54e-06296223575670
Pubmed

Identification of a genomic reservoir for new TRIM genes in primate genomes.

TRIM51 TRIM49D1 TRIM51G

1.91e-051996322144910
Pubmed

Identification of the Ped gene at the molecular level: the Q9 MHC class I transgene converts the Ped slow to the Ped fast phenotype.

HLA-E HLA-F

2.26e-0539627819451
Pubmed

Circadian clock disruption improves the efficacy of chemotherapy through p73-mediated apoptosis.

CRY2 CRY1

2.26e-05396221628572
Pubmed

The majority of H2-M3 is retained intracellularly in a peptide-receptive state and traffics to the cell surface in the presence of N-formylated peptides.

HLA-E HLA-F

2.26e-05396210430630
Pubmed

Novel mRNA species from a Q-subregion class-I gene of the murine major histocompatibility complex.

HLA-E HLA-F

2.26e-0539623443307
Pubmed

Regulation of apoptosis by the circadian clock through NF-kappaB signaling.

CRY2 CRY1

2.26e-05396221690409
Pubmed

Reduced alpha-adrenoceptor responsiveness and enhanced baroreflex sensitivity in Cry-deficient mice lacking a biological clock.

CRY2 CRY1

2.26e-05396215860530
Pubmed

Characterization of a new subfamily of class I genes in the H-2 complex of the mouse.

HLA-E HLA-F

2.26e-0539623378834
Pubmed

Qa-1-Restricted CD8+ T Cells Can Compensate for the Absence of Conventional T Cells during Viral Infection.

HLA-E HLA-F

2.26e-05396230970256
Pubmed

Molecular clocks in mouse skin.

CRY2 CRY1

2.26e-05396219037239
Pubmed

Further evidence for the role of cryptochromes in retinohypothalamic photoreception/phototransduction.

CRY2 CRY1

2.26e-05396215010208
Pubmed

Circadian clock molecules CLOCK and CRYs modulate fibrinolytic activity by regulating the PAI-1 gene expression.

CRY2 CRY1

2.26e-05396216970803
Pubmed

Protein expression and peptide binding suggest unique and interacting functional roles for HLA-E, F, and G in maternal-placental immune recognition.

HLA-E HLA-F

2.26e-05396212874228
Pubmed

Cell-autonomous clock of astrocytes drives circadian behavior in mammals.

CRY2 CRY1

2.26e-05396230630934
Pubmed

HLA-E, HLA-F, and HLA-G polymorphism: genomic sequence defines haplotype structure and variation spanning the nonclassical class I genes.

HLA-E HLA-F

2.26e-05396216570139
Pubmed

Role of the Ped gene and apoptosis genes in control of preimplantation development.

HLA-E HLA-F

2.26e-0539629604770
Pubmed

Evolution and molecular interactions of major histocompatibility complex (MHC)-G, -E and -F genes.

HLA-E HLA-F

2.26e-05396235925520
Pubmed

Quantitative analyses of cryptochrome-mBMAL1 interactions: mechanistic insights into the transcriptional regulation of the mammalian circadian clock.

CRY2 CRY1

2.26e-05396221521686
Pubmed

Loss of cryptochrome reduces cancer risk in p53 mutant mice.

CRY2 CRY1

2.26e-05396219188586
Pubmed

CRY1-CBS binding regulates circadian clock function and metabolism.

CRY2 CRY1

2.26e-05396232383312
Pubmed

Iron promotes oxidative cell death caused by bisretinoids of retina.

ABCA4 CP

2.26e-05396229686088
Pubmed

Circadian and Feeding Rhythms Orchestrate the Diurnal Liver Acetylome.

CRY2 CRY1

2.26e-05396228813682
Pubmed

Reduced expression of the murine HLA-G homolog Qa-2 is associated with malignancy, epithelial-mesenchymal transition and stemness in breast cancer cells.

HLA-E HLA-F

2.26e-05396228740236
Pubmed

A circadian clock regulates efflux by the blood-brain barrier in mice and human cells.

CRY2 CRY1

2.26e-05396233504784
GeneFamilyRing finger proteins|Tripartite motif containing|ARF GTPase family

TRIM16 TRIM51 TRIM49D1 TRIM48 TRIM51G

1.99e-059563559
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

IGFN1 LRRC4B LRRC4C LRRC4 UNC5D

2.44e-04161635593
GeneFamilyCyclins|F-boxes other

FBXO9 FBXO46 FBXO34

3.37e-0439633560
GeneFamilyRing finger proteins

TRIM51 ZNRF3 TRIM49D1 RNF43 RNF133 TRIM48

3.85e-0427563658
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HGF IGFN1 ABI3BP NAV3 NAV2 CP ADGRD1

2.22e-071959673c3703f092b6fc1b7333426fb5e2823bfb74bb57
ToppCelldroplet-Lung-nan-18m-Myeloid-Basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGF FBXO9 SLC41A3 CCR1 RNF43 CHST13

1.80e-06169966f2e20049a17eee533d49bd5f24a51962d123d132
ToppCelldroplet-Lung-nan-18m-Myeloid-basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGF FBXO9 SLC41A3 CCR1 RNF43 CHST13

1.80e-061699664c6892551e9dec94fc62b3beab1e6d424639a1e9
ToppCelldroplet-Lung-nan-21m-Myeloid-Basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGF FBXO9 SLC41A3 CCR1 RNF43 CHST13

1.99e-061729661b133be191252e7053faeacf9547730c3ae28d21
ToppCelldroplet-Lung-nan-21m-Myeloid-basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGF FBXO9 SLC41A3 CCR1 RNF43 CHST13

1.99e-06172966b3c53fd7e50f36de6a8585ae21d04e17932f262c
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MELTF IGFN1 ABCA4 NAV3 LRRC4C UNC5D

2.95e-061849662cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MELTF IGFN1 ABCA4 NAV3 LRRC4C UNC5D

2.95e-06184966ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MELTF IGFN1 ABCA4 NAV3 LRRC4C UNC5D

2.95e-061849662b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IGFN1 ABI3BP NAV3 NAV2 CP ADGRD1

3.99e-06194966c49f72441b3557e2c3a9c4239e68c0cf0652814b
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW08-Stem_cells-Neuroepithelial_cell|GW08 / Sample Type, Dataset, Time_group, and Cell type.

C5orf34 PTAR1 GREB1 TOP2A EVI5L FANCA

4.76e-062009664e077aa7faddcebdfc54667f8b3990704441005b
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

HGF ABI3BP NAV3 NAV2 ADGRG4 ADGRD1

4.76e-062009663dd022e974fec7013ba18f333da63f58fbf2dd7c
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW08-Stem_cells|GW08 / Sample Type, Dataset, Time_group, and Cell type.

C5orf34 PTAR1 GREB1 TOP2A EVI5L FANCA

4.76e-06200966d17ba4239e1fd702a3d757687110f0f2c6f91ef7
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_VISp_Agmat|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

IGFN1 STARD8 ABI3BP UNC5D ITPKA

2.23e-0515696509e0702400570089d9012dcf94dfb4827c97e49d
ToppCellfacs-Marrow-T_cells-18m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGF SLC41A3 CCR1 RNF43 CHST13

3.00e-05166965c22b0f3bf990d94b615a3aacee5de548da2db628
ToppCellfacs-Marrow-T_cells-18m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGF SLC41A3 CCR1 RNF43 CHST13

3.00e-051669650975fc165bcc7e85f053d9d0244fffe407c23571
ToppCelldroplet-Lung-18m-Hematologic-myeloid-Basophil/Mast_cell-basophil_l26|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HGF FBXO9 SLC41A3 RNF43 CHST13

3.18e-051689650e99ecd94ab8e5372e30433d7d0aa76b4d54257a
ToppCelldroplet-Lung-18m-Hematologic-myeloid-Basophil/Mast_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HGF FBXO9 SLC41A3 RNF43 CHST13

3.18e-0516896534722e14f28313f2e4644b3c1861ef12958cee9f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

C5orf34 GOLGA6L2 RECQL4 TOP2A FANCA

3.76e-0517496584da9faff088d05233183b425385beb054c92d1b
ToppCelldroplet-Lung-21m-Hematologic-myeloid-Basophil/Mast_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HGF FBXO9 SLC41A3 CCR1 CHST13

3.76e-0517496531f7127faabcb1092bb9827db625f57cf7d8240e
ToppCelldroplet-Lung-21m-Hematologic-myeloid-Basophil/Mast_cell-basophil_l26|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HGF FBXO9 SLC41A3 CCR1 CHST13

3.76e-051749658a8e98e62c2859c004b44dbce6974c9639ebeac6
ToppCellfacs-Marrow-KLS-24m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NOP16 WDR18 LRRC4B EMC8 TOP2A

3.86e-05175965f60167473be62d0ef86ce3614e63c0d1377e45b9
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IGFN1 ABI3BP NAV3 ADGRG4 ADGRD1

3.86e-05175965795a6564d5a75ffd35d39f5274b9e8d28708bbc8
ToppCellASK452-Epithelial-Secretory|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

FBXO9 NTS TMPRSS4 CP LRRC4

3.97e-05176965dd334c8a8a31dc26b2d558df0ef6bed6dc1a6610
ToppCellfacs-Marrow-T-cells-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGF SLC41A3 CCR1 RNF43 CHST13

4.19e-0517896541745a589567ca5ea6d06331f4c8da03595b5f5c
ToppCellfacs-Marrow-T-cells-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGF SLC41A3 CCR1 RNF43 CHST13

4.19e-05178965eb940dd64c973f68bcaad6069d3bd56383329db5
ToppCellRSV-Healthy-0|RSV / Virus stimulation, Condition and Cluster

C5orf34 ZSWIM3 HLA-F CPLANE1 CHN1

4.41e-05180965974044056e2f7e909cb11c6f6ca89e58bf95f7e5
ToppCellRSV-Healthy-0|Healthy / Virus stimulation, Condition and Cluster

C5orf34 ZSWIM3 HLA-F CPLANE1 CHN1

4.41e-05180965703a1d0f9536af94d56757eb01221878d7b7fe61
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA4 ZNRF3 TMPRSS4 LRRC4C UNC5D

4.77e-0518396592fbd83a9d13ee91065cbd479fb298f1fd564568
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-AT2_Progenitor|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NAPSA SORCS2 NAV2 CP RNF43

4.90e-051849657cc5796557379c3d1db078c1aeda40659c6e401c
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-Plasma_cell-B_c05-MZB1-XBP1|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

LGMN USO1 LRRC4 TOP2A EVI5L

4.90e-05184965af6522586d012e91241f3e06c60f9d1881e95646
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NAPSA ZNRF3 NAV2 CP RNF43

4.90e-05184965ab2f06906fc7a9931dfa0864ef506832b07fb93e
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NAPSA ZNRF3 NAV2 CP RNF43

5.16e-05186965e83718fabb057100835d3357df407f283d23fe16
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZNRF3 SORCS2 NAV2 CP RNF43

5.29e-0518796558d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MELTF ABCA4 ZNRF3 TMPRSS4 UNC5D

5.29e-05187965c41a2c81dd2ceef303f39f699032aa7d6ea67cf0
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NAPSA ZNRF3 NAV2 CP RNF43

5.43e-051889654bdf8d49af0e9da349b16e3f012e1b0eec04cc4f
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D175|Adult / Lineage, Cell type, age group and donor

ABI3BP NAV3 GREB1 ADGRG4 ADGRD1

5.70e-051909657dcca3469f3a3b70db0420cb94f7765f39492f06
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MELTF ABCA4 ABI3BP ZNRF3 TMPRSS4

5.70e-0519096559bbbd2c8d4b7ce46c54ca8022b1557e7e5eee2a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IGFN1 ABI3BP NAV3 ADGRG4 ADGRD1

5.85e-051919652c51850f5c559d665b8a27a12b75af9ed58dffe1
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-ciliated_cell-Epi-Ciliated|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

NAPSA SLC41A3 CIBAR2 CP CFAP46

5.99e-05192965a22952b885c8a7704a4a9602fa03e4f2c786bf75
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-ciliated_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

NAPSA SLC41A3 CIBAR2 CP CFAP46

5.99e-05192965dcf2d0c2e8868104c4dba410456207f0d947029a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IGFN1 ABI3BP NAV3 NAV2 ADGRD1

6.14e-0519396509a9ab029f01234459a88e3e994fe90ef4cbb8c6
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature4_(1)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CRY2 HLA-E DENND5A FBXO34 CRY1

6.14e-05193965dbf0fe496254320c894568c31e5f9ce63707d1b5
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HGF ABI3BP NAV3 GREB1 ADGRG4

6.45e-05195965f54bc4454270ff06e85596f98199372b50d0179f
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Basal_3|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

IGFN1 NTS TMPRSS4 DGKI CP

6.77e-051979654f8f23b1ef2eae9d300bd2c1a5cb7ef0163858a1
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ABI3BP NAV3 NAV2 CHN1 ADGRG4

6.77e-051979650dd71e399f253787fa546a7e90c5373180b89ffd
ToppCellParenchyma_Control_(B.)-Epithelial-TX-Basal_3|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

IGFN1 NTS TMPRSS4 DGKI CP

6.77e-051979652cff37f9d33951840a8f52ccbba6ca1a4bbe3ad9
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_only / Treatment groups by lineage, cell group, cell type

NAPSA ABCA4 SORCS2 CP RNF43

6.77e-051979656b6504c47c309bac4f790e2f372d454bbdea49e8
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Basal_3-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGFN1 NTS TMPRSS4 DGKI CP

6.77e-051979650f37afad46b94c748a149d9ee681472d7a3e6937
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NTS TMPRSS4 CP CPLANE1 CFAP46

6.93e-05198965d0ecace1fad24ce50b0935036fabb07e6c9e372d
ToppCellLPS_only-Epithelial_airway-airway_epithelial-Airway-Club|LPS_only / Treatment groups by lineage, cell group, cell type

NAV2 TMPRSS4 CIBAR2 CP HEPHL1

7.10e-05199965165ac94b2d56072ad43358b5127d77555221e2d8
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

NAPSA NAV2 CP RNF43 FBXO34

7.10e-05199965121de4e02585de3a3010398387c523bacf8ce546
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW08-Stem_cells|GW08 / Sample Type, Dataset, Time_group, and Cell type.

C5orf34 PTAR1 GREB1 EVI5L FANCA

7.27e-05200965691b3edf7d8449556e8bf611662eb85772959f0f
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

NAPSA ABCA4 NAV2 CP RNF43

7.27e-05200965ddfb1f006365bf16203ee49f20200f68220cc288
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW08-Stem_cells-Stem_cells|GW08 / Sample Type, Dataset, Time_group, and Cell type.

C5orf34 PTAR1 GREB1 EVI5L FANCA

7.27e-0520096536a110aa91a791fdf1142e7869e8aa0d342402d0
ToppCellControl_saline-Mesenchymal_myocytic-Pericyte-Pericyte_2|Control_saline / Treatment groups by lineage, cell group, cell type

HGF SULT1C2 CARD11 CHN1 ADGRD1

7.27e-05200965bc8949eb34482aca166c4602ff6ab876cb4c2c3c
ToppCellASK452-Epithelial-Secretory|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

FBXO9 NTS TMPRSS4 CP

1.91e-0413296449ba24e24b3127b5257a88a0ee0246c9843c580a
ToppCellPBMC-Control-Hematopoietic-Platelet-Platelet-plt_5|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ABI3BP SLIT1 LRRC4B LRRC4C

2.14e-0413696427a41463e6f16deb5b1d4f17fefded9959038c07
ToppCellPBMC-Control-Hematopoietic-Platelet-Platelet-plt_5|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ABI3BP SLIT1 LRRC4B LRRC4C

2.14e-0413696488b5c839d0446c6d6b7e81fc4d48f5e7e96eea11
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7.Syt6-Nefm_(Layer_6a)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

WNT2B HEPHL1 RNF133

2.28e-0455963b0d37faccc8d04433ee0e76cbce2410530c4c8a1
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7.Syt6-Nefm_(Layer_6a)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

WNT2B HEPHL1 RNF133

2.28e-0455963c3ebea1420b68638ed465a8cd8efba860650b795
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TNFRSF25 RECQL4 PTAR1 UNC5D

2.39e-0414096411e441c3435ad8911ab401ca7d4ae1d3e5fa6eac
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TNFRSF25 RECQL4 PTAR1 UNC5D

2.39e-0414096494444b92acfad64d811ebb1545dc1dab64473795
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_ALM_Macc1_Lrg1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

HJV IGFN1 STARD8 ITPKA

2.52e-04142964d08e1880425d285c4433014fe0242ac7ff7734af
ToppCellClub_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

ABCA4 NTS TMPRSS4 CP

3.03e-0414996481c813588bb5efb7b31141a75d387210dcb76094
ToppCellPND10-Immune-Immune_Myeloid-Granulocytic|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HGF SLC41A3 CCR1 CHST13

3.03e-04149964c9334f319a0c943268e54b6f0c9446736172c3a9
ToppCellPND07-28-samps-Mesenchymal-Pericyte-pericyte_F|PND07-28-samps / Age Group, Lineage, Cell class and subclass

MICAL1 SULT1C2 NTS LRRC4C

3.11e-041509642d0d6dc07dcfe28e3d7694c52d15d17dae2fd47b
ToppCellPND07-28-samps-Mesenchymal-Pericyte|PND07-28-samps / Age Group, Lineage, Cell class and subclass

MICAL1 SULT1C2 NTS LRRC4C

3.11e-041509645b111ec11a642d63fafa7e1422e36f81a2776531
ToppCellClub_cells-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

MELTF ZSWIM3 NTS CP

3.35e-0415396477030b0e033f3635b1bbe7552a28c074ea7bb106
ToppCellfacs-Marrow-T_cells-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FECH NAV3 DGKI RNF43

3.61e-041569645caefdc6cc86f2ac52abe8c8da821db14f476915
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RECQL4 TOP2A ITPKA FANCA

3.61e-04156964955547dfeb1b1ad4957b4338701055726b22619f
ToppCellfacs-Marrow-T_cells-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FECH NAV3 DGKI RNF43

3.61e-04156964758f57dc10fc5cad200bf5b310c10ec9b1405f23
ToppCelldroplet-Fat-Mat-18m-Epithelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEP1B SULT1C2 TMPRSS4 CIBAR2

3.61e-04156964cfd7f56f3155db677684827607e9008e975dbe70
ToppCelldroplet-Fat-Mat-18m-Epithelial-epithelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEP1B SULT1C2 TMPRSS4 CIBAR2

3.61e-041569640d79b4172896574b00faf00e87254f68d76f5512
ToppCelldroplet-Fat-Mat-18m-Epithelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEP1B SULT1C2 TMPRSS4 CIBAR2

3.61e-04156964f09150aacb6121f913648ed3918f9cd4f22c61f2
ToppCellPND28-Immune-Immune_Myeloid-Granulocytic-Basophil|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PIGQ SLC41A3 RNF43 CHST13

3.69e-041579648c42af7aa1f1b6f4fe2f8d00a8b4a800f121e804
ToppCellfacs-Marrow-T-cells-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGF SLC41A3 CCR1 CHST13

3.69e-04157964ed9c9feefc06c9536c03bedbc3397a2ee492a78e
ToppCellPND28-Immune-Immune_Myeloid-Granulocytic|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PIGQ SLC41A3 RNF43 CHST13

3.69e-04157964ee1be3c756b72fceac6b4ccb416dd4bd031a2193
ToppCellfacs-Marrow-T-cells-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGF SLC41A3 CCR1 CHST13

3.69e-04157964fddcb24776b9f86e000208bae54541b15b2adefd
ToppCellPND28-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PIGQ SLC41A3 RNF43 CHST13

3.69e-04157964008f938a338f43c3251dcac574f1b4f689926c71
ToppCell367C-Lymphocytic-CD4_T-cell-Treg_cell_3|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

GPHN NAPSA CP CHN1

3.69e-041579646a0aa66964eecbbc232abf1d2e6c8422e4ce69d0
ToppCellfacs-Heart-RV-24m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYC1 DGKI RSPH6A CFAP46

3.78e-041589642ef43d14ee65d004dc62c12ff209bbe12e4db681
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage_4|368C / Donor, Lineage, Cell class and subclass (all cells)

LGMN CCR1 IHH CHST13

3.78e-04158964f9cfb110342be3c91aba9914805332f22ba89101
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

B3GNT6 NTS TMPRSS4 CP

3.87e-0415996460b1f4dce2ce0911160fda17f137c064da31e2eb
ToppCellfacs-Heart-RV-24m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RECQL4 DGKI RSPH6A IHH

3.97e-0416096441d6c811c445c0ba9b6a2deb10a3b6b793172582
ToppCellfacs-Heart-RV-24m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RECQL4 DGKI RSPH6A IHH

3.97e-04160964c1d03c0ac9c12615a06499209fcdf18e9b6f1fba
ToppCell(1)_Control_(PBS)-(4)_COL2.3+_osteoblasts|(1)_Control_(PBS) / Stress and Cell class

TRIM16 NAPSA CHN1 TOP2A

3.97e-041609648450466fc2465c56798df2b520edd23c2c2e941c
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L2/3_IT|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

IGFN1 STARD8 ABI3BP ITPKA

4.06e-04161964e3327c296d48e821004e61a573abb75624a6f040
ToppCell367C-Lymphocytic-CD4_T-cell-Treg_cell_3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

GPHN NAPSA CP CHN1

4.06e-0416196422fea192cd5f6d3544533d8b10e1d74dfedf0f05
ToppCelldroplet-Heart-nan-24m-Hematologic-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA FECH CARD11 FANCA

4.06e-041619647e60001637ef0f6fc67ef8a36ab80ebb25b0b0ab
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Epcam____brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEP1B NAPSA CP IHH

4.16e-04162964de0fde4310a56dc96bfc134c44d104993526d9bc
ToppCelldroplet-Heart-nan-18m-Hematologic-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FECH CARD11 TOP2A FANCA

4.16e-041629647f425a3983325a5a3ea33f812b15aa010cc55de0
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Pleural_Mac|Myeloid_cells / Location, Cell class and cell subclass

LGMN NTS CCR1 LRRC4B

4.36e-04164964362c16ed7fb37bf16601fd5e059d3f3e2ed692b4
ToppCellPND14-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HGF CCR1 RNF43 CHST13

4.36e-04164964f4de9f18134a06f3d7fcf5b50b8e21c1506e2083
ToppCellPND14-Immune-Immune_Myeloid-Granulocytic-Basophil|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HGF CCR1 RNF43 CHST13

4.36e-04164964dc22b1fef49c1557a0b63c536eaba574dfcab715
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LGMN RECQL4 CCR1 TOP2A

4.56e-04166964bb8135119dc37fdbba476599a56d368f422688dc
ToppCelldroplet-Kidney-nan-18m-Epithelial-Epcam____brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEP1B NAPSA CP IHH

4.66e-04167964ed7e785dcd25777f64e0c2596ada4f5a5ea17121
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA4 ABI3BP SORCS2 CIBAR2

4.66e-041679642184c2760b6142e62124a2454a552723e20d4f61
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RECQL4 NAV2 TOP2A FANCA

4.66e-04167964bc132b51dec4e8f1cd2b2cd89f83641976e09292
ToppCelldroplet-Kidney-nan-3m-Epithelial-Epcam____brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEP1B NAPSA SORCS2 WDR18

4.66e-0416796440d102e01ccbc7262d00fafd59ca5234909009cb
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEP1B NAPSA CP IHH

4.77e-04168964b14fd50232887b6dca1f39014d43c6f66e5c3b5c
Diseasegraft-versus-host disease (implicated_via_orthology)

HLA-E HLA-F

2.04e-047932DOID:0081267 (implicated_via_orthology)
Diseaseautism spectrum disorder (is_marker_for)

SLC25A12 IHH

2.04e-047932DOID:0060041 (is_marker_for)
DiseaseX-linked infantile spasms

PIGQ CAMK2G

2.72e-048932C4552072
Diseaseretinal degeneration (is_implicated_in)

HGF ABCA4

3.49e-049932DOID:8466 (is_implicated_in)
DiseaseHereditary hemochromatosis

HJV CP

6.35e-0412932C0392514
DiseaseHemochromatosis

HJV CP

6.35e-0412932C0018995
DiseaseSeasonal Affective Disorder

CRY2 CRY1

1.15e-0316932C0085159
Disease5-oxoproline measurement

CYC1 LRRC4C

1.15e-0316932EFO_0010988
DiseaseAdrenocortical carcinoma

ZNRF3 TOP2A

1.45e-0318932C0206686
Diseaseaxial length measurement

MELTF ZNRF3 LRRC4C

1.87e-0377933EFO_0005318
DiseaseHepatitis, Chronic

HGF CP

2.18e-0322932C0019189
DiseaseChronic active hepatitis

HGF CP

2.18e-0322932C0520463
DiseaseCryptogenic Chronic Hepatitis

HGF CP

2.18e-0322932C0524611
DiseaseChronic Persistent Hepatitis

HGF CP

2.18e-0322932C0149519
Diseasepallidum volume change measurement, age at assessment

SLIT1 SORCS2

2.81e-0325932EFO_0008007, EFO_0021494
Diseaseblood tin measurement

ABI3BP SLIT1

2.81e-0325932EFO_0021530

Protein segments in the cluster

PeptideGeneStartEntry
IPHHFRAIVWQLLCS

EVI5L

116

Q96CN4
EHPHANHGRFSLCEW

CIBAR2

266

Q6ZTR7
HFHLDHCGALPWFLQ

CPSF3

71

Q9UKF6
WLRNANPLYSHHECH

ABCA4

41

P78363
SFIQIPHEAFHRHAW

ADGRD1

406

Q6QNK2
RHHLASFQWHTICLI

ADGRG4

111

Q8IZF6
HWVPACHSFNRAIHK

FBXO34

686

Q9NWN3
QWLHHRHFPLEDVVF

CFAP46

1226

Q8IYW2
CTFLRWASEPEHDHR

CYC1

271

P08574
CGNANPHKWVRHLSH

AP4M1

431

O00189
PSWEHILFTCCHNRH

NT5C

156

Q8TCD5
HFHTCRVQGAWPLLD

HJV

181

Q6ZVN8
AHHPISDHEATLRCW

HLA-F

211

P30511
PEYHRCILTWHHQEP

GPHN

671

Q9NQX3
RTPGIWLLHCHVTDH

CP

1031

P00450
THHPISDHEATLRCW

HLA-E

211

P13747
HCVPISAHHRWNFDD

DRG1

266

Q9Y295
PHTLFVLIHDHAHWD

GREB1

761

Q4ZG55
DVSLCRWHPKPYHHD

FBXO46

541

Q6PJ61
LHWFPYCRSHVLSHA

OR51B6

161

Q9H340
LELHHNFRWVLCANH

NAV3

2166

Q8IVL0
LHHLCWGPLRMFNEH

PI4KA

1211

P42356
YLVELHLHHNPWNCD

LRRC4

291

Q9HBW1
RHNVLHLWPFTIHDL

MICAL1

121

Q8TDZ2
LHHSWHFAGELQRAL

GOLGA6L2

171

Q8N9W4
IHLHHNPWNCNCDIL

LRRC4C

296

Q9HCJ2
ICQRWDHQTPHRHKF

HGF

231

P14210
LFVHDHCHRAGVWLI

ITPKA

401

P23677
QLHKICHSRAFQHWE

NTS

106

P30990
WIHHLARHAVACFLT

CRY2

371

Q49AN0
RSLPYHVHWAQQDCH

CPLANE1

226

Q9H799
HTCSLHFPHESLREW

CCR1

181

P32246
RFNKLIWIHHSCHIT

FBXO9

396

Q9UK97
PRWCFLDDRSQEHLH

DGKI

826

O75912
IHWRCEEPSAHHNSI

CASC2

36

Q6XLA1
RQDFHQWAIHEHFLP

FANCA

951

O15360
GWIHHLARHAVACFL

CRY1

351

Q16526
LVCLGARDHLLHHWI

DENND5A

1221

Q6IQ26
FPTLRHHDLHSWHAE

DGCR2

241

P98153
ELFADHPGTWLLHCH

HEPHL1

1036

Q6MZM0
HPGTWLLHCHVSDHI

HEPHL1

1041

Q6MZM0
CPSAAWHFRHRLLHP

IGFN1

336

Q86VF2
HHENRWRCRDPHHDY

EMC8

146

O43402
RWPTHHLLIQCFADH

FECH

226

P22830
HNFKVHTFRGPHWCE

CHN1

206

P15882
HLHLLDWLAARCPHA

B3GNT6

201

Q6ZMB0
VPHLHRWNFCDSLLQ

C5orf34

306

Q96MH7
SLIHHQWVLTAAHCL

PRSS46P

71

E5RG02
NLSETRCPHHIWHIR

MEP1B

421

Q16820
RCPHHIWHIRNFTQF

MEP1B

426

Q16820
RHEWLCARVDPFTDH

CARD11

811

Q9BXL7
HRRDGKWLNVHYHCS

CAMK2G

536

Q13555
VADHHLAQLAFWPLR

IHH

351

Q14623
HRLERVHLNHNPWHC

LRRC4B

301

Q9NT99
NCCFEHRHHEWLLGP

HGH1

226

Q9BTY7
WVHHTQHILPQGRCT

RSPH6A

541

Q9H0K4
ETPHFTCKGHRHWVL

NLE1

146

Q9NVX2
WLSNCPIAVTHFLHN

USO1

501

O60763
HFFHKNCIDPWILPH

RNF133

276

Q8WVZ7
EHRYHRHCPAEWAAE

TRIM48

136

Q8IWZ4
QRLLLSPLHHADDWH

RHBDD1

66

Q8TEB9
YPGHETLWCHRRHIF

PTAR1

306

Q7Z6K3
TEWRQCHLARVPAHA

MELTF

266

P08582
ETLLCYLELHPHHWL

RECQL4

921

O94761
PHHWLELLATTYTHC

RECQL4

931

O94761
ARLAALHHWHCLPWD

PIGQ

626

Q9BRB3
HNFRWVLCANHTEPV

NAV2

2271

Q8IVL1
PPDCHLHLHLRWADN

SORCS2

496

Q96PQ0
LHEFHRNCVDPWLHQ

RNF43

291

Q68DV7
RLTWHQALDPDNHCI

SLC41A3

431

Q96GZ6
HVWSHHALPITDLHC

WDR18

166

Q9BV38
APRIECSHIRHAWDH

NOP16

31

Q9Y3C1
FRHPQWTHRGDCLVH

STARD8

206

Q92502
GQTIIHHHIPFNWDC

SLC25A12

116

O75746
HHHIPFNWDCEFIRL

SLC25A12

121

O75746
EPFNEHWERAHALCH

CHST13

241

Q8NET6
HWERAHALCHPCRLR

CHST13

246

Q8NET6
FHSHLPELHIFQPEW

ZNF321P

91

Q8N8H1
FVWPSLFHLHERTHT

ZNF823

201

P16415
RVWNHIVHLEDHLFC

UGT1A10

206

Q9HAW8
IPNARQFAEWICHLH

MTREX

286

P42285
HRNHIHCPIEWAAEE

TRIM51

121

Q9BSJ1
CQRAIIQHRHPFIEW

SULT1C2

71

O00338
DPHWVLTAAHCFRKH

TMPRSS4

236

Q9NRS4
PHCADVSSEHWNIHL

UNC5D

621

Q6UXZ4
LVCPQDTFLAWENHH

TNFRSF25

71

Q93038
YWVPDHEILHCHNCR

ZFYVE1

711

Q9HBF4
FIHHNWPSLLRHRFL

TOP2A

556

P11388
HRNHRHCPTEWAAEE

TRIM51G

121

A0A3B3IT33
WYHLPCRHILALLHT

ZSWIM3

556

Q96MP5
HRYHRHCPAEWAAEE

TRIM49D1

121

C9J1S8
HRKCVDPWLLQHHTC

ZNRF3

316

Q9ULT6
HNWRYCPAHHSPLSA

TRIM16

126

O95361
LWIHCLQRLFFENHP

PLEKHG2

401

Q9H7P9
FLINPHHDWTLPSHC

ABI3BP

136

Q7Z7G0
HHDWTLPSHCPNDRF

ABI3BP

141

Q7Z7G0
RLHSNHLFCDCHLAW

SLIT1

211

O75093
AFRPSAHLIQHWRIH

ZNF850

261

A8MQ14
FRHHRWNCTTLDRDH

WNT2B

111

Q93097
WHHQCPKCTRVFRHL

ZBTB26

271

Q9HCK0
EALLHFRTHCFNWHS

LGMN

381

Q99538
SRRCHFFSVPCWLHH

NAPSA

106

O96009