Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	axonemal dynein complex assembly	TTC12 DRC1 CFAP57 DNAI3	1.19e-05	41	71	4	GO:0070286
GeneOntologyBiologicalProcess	cilium movement	INPP5B TTC29 TTC12 DRC1 CFAP57 DNAI3 DNAH9	3.20e-05	261	71	7	GO:0003341
GeneOntologyBiologicalProcess	intracellular protein transport	BMP4 AP1B1 AP2B1 COG7 TGFBRAP1 SLC35D3 BAG3 ERP29 CDK1 CAMK1 SNX5	4.23e-05	740	71	11	GO:0006886
GeneOntologyBiologicalProcess	cilium movement involved in cell motility	INPP5B TTC12 DRC1 CFAP57 DNAI3 DNAH9	8.56e-05	210	71	6	GO:0060294
GeneOntologyBiologicalProcess	lymphoid progenitor cell differentiation	BMP4 LIG4 FNIP1	9.60e-05	26	71	3	GO:0002320
GeneOntologyBiologicalProcess	cilium-dependent cell motility	INPP5B TTC12 DRC1 CFAP57 DNAI3 DNAH9	9.74e-05	215	71	6	GO:0060285
GeneOntologyBiologicalProcess	cilium or flagellum-dependent cell motility	INPP5B TTC12 DRC1 CFAP57 DNAI3 DNAH9	9.74e-05	215	71	6	GO:0001539
GeneOntologyBiologicalProcess	intracellular transport	TRAPPC11 BMP4 AP1B1 AP2B1 COG7 TGFBRAP1 SLC35D3 BAG3 ERP29 CDK1 CAMK1 ATP9A RUFY1 SNX5 NUP205	1.44e-04	1496	71	15	GO:0046907
GeneOntologyBiologicalProcess	cardiac jelly development	BMP2 BMP4	1.74e-04	6	71	2	GO:1905072
GeneOntologyBiologicalProcess	positive regulation of protein binding	BMP2 BMP4 MARK3 PLXND1	2.11e-04	85	71	4	GO:0032092
GeneOntologyBiologicalProcess	positive regulation of odontoblast differentiation	BMP2 BMP4	2.43e-04	7	71	2	GO:1901331
GeneOntologyBiologicalProcess	microtubule-based movement	INPP5B TTC29 TTC12 BAG3 DRC1 CFAP57 DNAI3 DNAH9	2.86e-04	493	71	8	GO:0007018
GeneOntologyBiologicalProcess	heart induction	BMP2 BMP4	3.23e-04	8	71	2	GO:0003129
GeneOntologyBiologicalProcess	positive regulation of neuroepithelial cell differentiation	BMP2 BMP4	3.23e-04	8	71	2	GO:1902913
GeneOntologyBiologicalProcess	regulation of intracellular protein transport	BMP4 SLC35D3 BAG3 CDK1 CAMK1	4.12e-04	182	71	5	GO:0033157
GeneOntologyBiologicalProcess	regulation of heart morphogenesis	BMP2 BMP4	4.14e-04	9	71	2	GO:2000826
GeneOntologyBiologicalProcess	ameloblast differentiation	BMP2 BMP4	4.14e-04	9	71	2	GO:0036305
GeneOntologyBiologicalProcess	regulation of binding	GTPBP4 BMP2 BMP4 MARK3 CAMK1 PLXND1 DOT1L	4.22e-04	396	71	7	GO:0051098
GeneOntologyCellularComponent	early endosome	AP1B1 TGFBRAP1 INPP5B SLC35D3 ATP9A ECPAS RUFY1 DAGLA SNX5	3.53e-05	481	71	9	GO:0005769
GeneOntologyCellularComponent	axonemal dynein complex	DRC1 DNAI3 DNAH9	8.18e-05	25	71	3	GO:0005858
GeneOntologyCellularComponent	early endosome membrane	INPP5B SLC35D3 ATP9A RUFY1 DAGLA SNX5	8.39e-05	212	71	6	GO:0031901
GeneOntologyCellularComponent	vesicle tethering complex	COG2 TRAPPC11 COG7 TGFBRAP1	1.06e-04	72	71	4	GO:0099023
GeneOntologyCellularComponent	Golgi transport complex	COG2 COG7	5.03e-04	10	71	2	GO:0017119
GeneOntologyCellularComponent	trans-Golgi network membrane	COG2 AP1B1 COG7 ATP9A	5.76e-04	112	71	4	GO:0032588
GeneOntologyCellularComponent	dynein complex	DRC1 DNAI3 DNAH9	8.23e-04	54	71	3	GO:0030286
Domain	-	AP1B1 AP2B1	1.31e-05	2	68	2	2.60.40.1150
Domain	Clathrin_b-adaptin_app_Ig-like	AP1B1 AP2B1	1.31e-05	2	68	2	IPR013037
Domain	AP_complex_bsu_1_2_4	AP1B1 AP2B1	3.91e-05	3	68	2	IPR016342
Domain	B2-adapt-app_C	AP1B1 AP2B1	3.91e-05	3	68	2	PF09066
Domain	B-adaptin_app_sub_C	AP1B1 AP2B1	7.80e-05	4	68	2	IPR015151
Domain	B2-adapt-app_C	AP1B1 AP2B1	7.80e-05	4	68	2	SM01020
Domain	AP_beta	AP1B1 AP2B1	1.30e-04	5	68	2	IPR026739
Domain	Beta2_adaptin/TBP_C_dom	AP1B1 AP2B1	1.94e-04	6	68	2	IPR012295
Domain	-	AP1B1 AP2B1	1.94e-04	6	68	2	3.30.310.10
Domain	Coatomer/calthrin_app_sub_C	AP1B1 AP2B1	3.61e-04	8	68	2	IPR009028
Domain	Clathrin_a/b/g-adaptin_app_Ig	AP1B1 AP2B1	4.63e-04	9	68	2	IPR008152
Domain	Alpha_adaptinC2	AP1B1 AP2B1	4.63e-04	9	68	2	PF02883
Domain	Alpha_adaptinC2	AP1B1 AP2B1	4.63e-04	9	68	2	SM00809
Domain	MAC_perforin	BRINP1 C8A	5.77e-04	10	68	2	IPR001862
Domain	WW	BAG3 PLEKHA7 UTRN	6.67e-04	47	68	3	PF00397
Domain	MACPF	BRINP1 C8A	7.03e-04	11	68	2	PF01823
Domain	WW	BAG3 PLEKHA7 UTRN	7.10e-04	48	68	3	SM00456
Domain	MACPF	BRINP1 C8A	8.42e-04	12	68	2	SM00457
Domain	MACPF	BRINP1 C8A	8.42e-04	12	68	2	IPR020864
Domain	Coatomer/clathrin_app_Ig-like	AP1B1 AP2B1	8.42e-04	12	68	2	IPR013041
Domain	WW_DOMAIN_2	BAG3 PLEKHA7 UTRN	8.48e-04	51	68	3	PS50020
Domain	WW_DOMAIN_1	BAG3 PLEKHA7 UTRN	8.48e-04	51	68	3	PS01159
Domain	WW_dom	BAG3 PLEKHA7 UTRN	8.98e-04	52	68	3	IPR001202
Domain	-	AP1B1 AP2B1 TTC12 RICTOR ECPAS	1.29e-03	222	68	5	1.25.10.10
Domain	Clathrin/coatomer_adapt-like_N	AP1B1 AP2B1	1.33e-03	15	68	2	IPR002553
Domain	Adaptin_N	AP1B1 AP2B1	1.33e-03	15	68	2	PF01602
Domain	ARM-like	AP1B1 AP2B1 TTC12 RICTOR ECPAS	3.02e-03	270	68	5	IPR011989
Pathway	KEGG_MEDICUS_PATHOGEN_HIV_VPR_TO_WEE1_CELL_CYCLE_G2M	CCNB3 CDK1	1.22e-04	5	50	2	M49022
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PTCH1_TO_HEDGEHOG_SIGNALING_PATHWAY	BMP2 BMP4 WNT8A	1.44e-04	29	50	3	M47372
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_SMO_TO_HEDGEHOG_SIGNALING_PATHWAY	BMP2 BMP4 WNT8A	1.44e-04	29	50	3	M47377
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	PLEKHG1 AP1B1 MARK3 RICTOR ECPAS PLEKHA7 UTRN SNX5	4.01e-06	446	72	8	24255178
Pubmed	Divergent and Compensatory Effects of BMP2 and BMP4 on the VSMC Phenotype and BMP4's Role in Thoracic Aortic Aneurysm Development.	BMP2 BMP4	4.23e-06	2	72	2	38727271
Pubmed	Cross-talk between fibroblast growth factor and bone morphogenetic proteins regulates gap junction-mediated intercellular communication in lens cells.	BMP2 BMP4	4.23e-06	2	72	2	18400943
Pubmed	Phenotype characterization and sequence analysis of BMP2 and BMP4 variants in two Mexican families with oligodontia.	BMP2 BMP4	4.23e-06	2	72	2	23079991
Pubmed	Epithelial Bone Morphogenic Protein 2 and 4 Are Indispensable for Tooth Development.	BMP2 BMP4	4.23e-06	2	72	2	34483952
Pubmed	Rare variants in BMP2 and BMP4 found in otosclerosis patients reduce Smad signaling.	BMP2 BMP4	4.23e-06	2	72	2	24492129
Pubmed	Polymorphisms in BMP2/BMP4, with estimates of mean lung dose, predict radiation pneumonitis among patients receiving definitive radiotherapy for non-small cell lung cancer.	BMP2 BMP4	4.23e-06	2	72	2	28574846
Pubmed	BMP2/BMP4 colorectal cancer susceptibility loci in northern and southern European populations.	BMP2 BMP4	4.23e-06	2	72	2	23161572
Pubmed	Bone morphogenetic proteins 2 and 4 are selectively expressed by late outgrowth endothelial progenitor cells and promote neoangiogenesis.	BMP2 BMP4	4.23e-06	2	72	2	18818419
Pubmed	BMP2 and BMP4 variations and risk of non-syndromic cleft lip and palate.	BMP2 BMP4	4.23e-06	2	72	2	27591802
Pubmed	Histone deacetylases control neurogenesis in embryonic brain by inhibition of BMP2/4 signaling.	BMP2 BMP4	4.23e-06	2	72	2	18628975
Pubmed	Bone morphogenetic protein 4 inhibits insulin secretion from rodent beta cells through regulation of calbindin1 expression and reduced voltage-dependent calcium currents.	BMP4 CALB1	4.23e-06	2	72	2	25828920
Pubmed	Abrogation of epithelial BMP2 and BMP4 causes Amelogenesis Imperfecta by reducing MMP20 and KLK4 expression.	BMP2 BMP4	4.23e-06	2	72	2	27146352
Pubmed	Inhibition of BMP2 and BMP4 Represses Barrett's Esophagus While Enhancing the Regeneration of Squamous Epithelium in Preclinical Models.	BMP2 BMP4	4.23e-06	2	72	2	36706916
Pubmed	Titanium With Nanotopography Induces Osteoblast Differentiation by Regulating Endogenous Bone Morphogenetic Protein Expression and Signaling Pathway.	BMP2 BMP4	4.23e-06	2	72	2	26681207
Pubmed	Association of bone morphogenetic proteins with otosclerosis.	BMP2 BMP4	4.23e-06	2	72	2	18021008
Pubmed	Cloning of rat type I receptor cDNA for bone morphogenetic protein-2 and bone morphogenetic protein-4, and the localization compared with that of the ligands.	BMP2 BMP4	4.23e-06	2	72	2	8896987
Pubmed	Hypertrophy is induced during the in vitro chondrogenic differentiation of human mesenchymal stem cells by bone morphogenetic protein-2 and bone morphogenetic protein-4 gene transfer.	BMP2 BMP4	4.23e-06	2	72	2	19799789
Pubmed	BMP-2 induced Dspp transcription is mediated by Dlx3/Osx signaling pathway in odontoblasts.	BMP2 BMP4	4.23e-06	2	72	2	28883412
Pubmed	Mutation of the TRPM3 cation channel underlies progressive cataract development and lens calcification associated with pro-fibrotic and immune cell responses.	TYR TRPM3	4.23e-06	2	72	2	33484482
Pubmed	Bone morphogenetic protein signaling is involved in human mesenchymal stem cell survival in serum-free medium.	BMP2 BMP4	4.23e-06	2	72	2	19473100
Pubmed	BMP-2 vs. BMP-4 expression and activity in glucocorticoid-arrested MC3T3-E1 osteoblasts: Smad signaling, not alkaline phosphatase activity, predicts rescue of mineralization.	BMP2 BMP4	4.23e-06	2	72	2	19021035
Pubmed	Lack of effect of bone morphogenetic protein 2 and 4 gene polymorphisms on bone density in postmenopausal Turkish women.	BMP2 BMP4	4.23e-06	2	72	2	21128211
Pubmed	Genetic variation in bone morphogenetic proteins family members (BMPs 2 and 4) and hypertension risk in middle-aged men: The TAMRISK study.	BMP2 BMP4	4.23e-06	2	72	2	29390526
Pubmed	Bone morphogenetic protein-2 antagonizes bone morphogenetic protein-4 induced cardiomyocyte hypertrophy and apoptosis.	BMP2 BMP4	4.23e-06	2	72	2	24648278
Pubmed	Bmp2 and Bmp4 exert opposing effects in hypoxic pulmonary hypertension.	BMP2 BMP4	4.23e-06	2	72	2	20042692
Pubmed	The daf-4 gene encodes a bone morphogenetic protein receptor controlling C. elegans dauer larva development.	BMP2 BMP4	4.23e-06	2	72	2	8413626
Pubmed	Heparan sulfate acts as a bone morphogenetic protein coreceptor by facilitating ligand-induced receptor hetero-oligomerization.	BMP2 BMP4	4.23e-06	2	72	2	20861306
Pubmed	Bone morphogenetic protein-2 and -4 expression during murine orofacial development.	BMP2 BMP4	4.23e-06	2	72	2	8651889
Pubmed	Establishment of Immortalized BMP2/4 Double Knock-Out Osteoblastic Cells Is Essential for Study of Osteoblast Growth, Differentiation, and Osteogenesis.	BMP2 BMP4	4.23e-06	2	72	2	26595646
Pubmed	Bmp2 and Bmp4 accelerate alveolar bone development.	BMP2 BMP4	4.23e-06	2	72	2	25491151
Pubmed	SARS-CoV-2 uses Spike glycoprotein to control the host's anaerobic metabolism by inhibiting LDHB.	CLPP HK1 AP2B1 BAG3 ERP29 PSMD12 CDK1 ECPAS NUP205	4.53e-06	607	72	9	39147351
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	GTPBP4 AP1B1 AP2B1 COG7 PSMD12 CDK1 ECPAS WDR26 NUP205	6.77e-06	638	72	9	33239621
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	HK1 AP1B1 AP2B1 COG7 BAG3 PSMD12 CDK1 ECPAS RUFY1 WDR26 SNX5 SPDL1 NUP205	8.09e-06	1455	72	13	22863883
Pubmed	Chromosomal localization of seven members of the murine TGF-beta superfamily suggests close linkage to several morphogenetic mutant loci.	TYR BMP2 BMP4	1.10e-05	21	72	3	1970330
Pubmed	A Cataract-Causing Mutation in the TRPM3 Cation Channel Disrupts Calcium Dynamics in the Lens.	TYR TRPM3	1.27e-05	3	72	2	38334649
Pubmed	Serum Levels of Bone Morphogenetic Proteins 2 and 4 in Patients with Acute Myocardial Infarction.	BMP2 BMP4	1.27e-05	3	72	2	32992577
Pubmed	The Spemann organizer signal noggin binds and inactivates bone morphogenetic protein 4.	BMP2 BMP4	1.27e-05	3	72	2	8752214
Pubmed	Thrombospondin-1 (TSP-1), a new bone morphogenetic protein-2 and -4 (BMP-2/4) antagonist identified in pituitary cells.	BMP2 BMP4	1.27e-05	3	72	2	28747434
Pubmed	BMP signaling is required for adult skeletal homeostasis and mediates bone anabolic action of parathyroid hormone.	BMP2 BMP4	1.27e-05	3	72	2	27567726
Pubmed	Bone morphogenetic protein (BMP)-7 but not BMP-2 and BMP-4 improves maintenance of primitive peripheral blood-derived hematopoietic progenitor cells (HPC) cultured in serum-free medium supplemented with early acting cytokines.	BMP2 BMP4	1.27e-05	3	72	2	18029192
Pubmed	Bone Morphogenetic Protein 2 Coordinates Early Tooth Mineralization.	BMP2 BMP4	1.27e-05	3	72	2	29489425
Pubmed	Peroxisome proliferator-activated receptor activity is involved in the osteoblastic differentiation regulated by bone morphogenetic proteins and tumor necrosis factor-α.	BMP2 BMP4	1.27e-05	3	72	2	21888945
Pubmed	Single-nucleotide polymorphisms and haplotypes of bone morphogenetic protein genes and peripheral bone mineral density in young Korean men and women.	BMP2 BMP4	1.27e-05	3	72	2	16604289
Pubmed	Gremlin1 preferentially binds to bone morphogenetic protein-2 (BMP-2) and BMP-4 over BMP-7.	BMP2 BMP4	1.27e-05	3	72	2	25378054
Pubmed	Cooperation of endoderm-derived BMP2 and extraembryonic ectoderm-derived BMP4 in primordial germ cell generation in the mouse.	BMP2 BMP4	1.27e-05	3	72	2	11401407
Pubmed	Evidence for involvement of activin A and bone morphogenetic protein 4 in mammalian mesoderm and hematopoietic development.	BMP2 BMP4	1.27e-05	3	72	2	7799920
Pubmed	Noggin is a negative regulator of neuronal differentiation in developing neocortex.	BMP2 BMP4	1.27e-05	3	72	2	10657699
Pubmed	CDK1-Mediated Phosphorylation of BAG3 Promotes Mitotic Cell Shape Remodeling and the Molecular Assembly of Mitotic p62 Bodies.	BAG3 CDK1	1.27e-05	3	72	2	34685619
Pubmed	Apoptosis induction and reduced proliferation in human osteoblasts by rhBMP-2, -4 and -7.	BMP2 BMP4	1.27e-05	3	72	2	19240369
Pubmed	Multiple common susceptibility variants near BMP pathway loci GREM1, BMP4, and BMP2 explain part of the missing heritability of colorectal cancer.	BMP2 BMP4	1.27e-05	3	72	2	21655089
Pubmed	Regulation of bone morphogenetic protein signalling in human pulmonary vascular development.	BMP2 BMP4	1.27e-05	3	72	2	17992660
Pubmed	Protein related to DAN and cerberus is a bone morphogenetic protein antagonist that participates in ovarian paracrine regulation.	BMP2 BMP4	1.27e-05	3	72	2	15039429
Pubmed	Expression of bioactive bone morphogenetic proteins in the subacromial bursa of patients with chronic degeneration of the rotator cuff.	BMP2 BMP4	1.27e-05	3	72	2	16719933
Pubmed	Overlapping and differential localization of Bmp-2, Bmp-4, Msx-2 and apoptosis in the endocardial cushion and adjacent tissues of the developing mouse heart.	BMP2 BMP4	1.27e-05	3	72	2	11512673
Pubmed	Dynamics and cellular localization of Bmp2, Bmp4, and Noggin transcription in the postnatal mouse skeleton.	BMP2 BMP4	1.27e-05	3	72	2	25043193
Pubmed	BMP-2 and -4 produced by vascular smooth muscle cells from atherosclerotic lesions induce monocyte chemotaxis through direct BMPRII activation.	BMP2 BMP4	1.27e-05	3	72	2	24814649
Pubmed	Genetic variants in bone morphogenetic proteins signaling pathway might be involved in palatal rugae phenotype in humans.	BMP2 BMP4	1.27e-05	3	72	2	34135450
Pubmed	Agrin binds BMP2, BMP4 and TGFbeta1.	BMP2 BMP4	1.27e-05	3	72	2	20505824
Pubmed	Bone morphogenetic protein 1 prodomain specifically binds and regulates signaling by bone morphogenetic proteins 2 and 4.	BMP2 BMP4	1.27e-05	3	72	2	17255107
Pubmed	Type II collagen accumulation in overlying dermo-epidermal junction of pilomatricoma is mediated by bone morphogenetic protein 2 and 4.	BMP2 BMP4	1.27e-05	3	72	2	15102076
Pubmed	Conditional deletion of BMP7 from the limb skeleton does not affect bone formation or fracture repair.	BMP2 BMP4	1.27e-05	3	72	2	19780203
Pubmed	Investigation of the association of BMP gene variants with nephropathy in Type 1 diabetes mellitus.	BMP2 BMP4	1.27e-05	3	72	2	20546278
Pubmed	Evaluation of the Genetic Association and mRNA Expression of the COL1A1, BMP2, and BMP4 Genes in the Development of Otosclerosis.	BMP2 BMP4	1.27e-05	3	72	2	32379989
Pubmed	Bmp signaling in molar cusp formation.	BMP2 BMP4	1.27e-05	3	72	2	30980961
Pubmed	Primitive CML cell expansion relies on abnormal levels of BMPs provided by the niche and on BMPRIb overexpression.	BMP2 BMP4	1.27e-05	3	72	2	24100446
Pubmed	Bone morphogenetic proteins and secreted frizzled related protein 2 maintain the quiescence of adult mammalian retinal stem cells.	BMP2 BMP4	1.27e-05	3	72	2	23843349
Pubmed	Association of bone morphogenetic proteins with spinal fusion in ankylosing spondylitis.	BMP2 BMP4	1.27e-05	3	72	2	20682677
Pubmed	Direct BMP2/4 signaling through BMP receptor IA regulates fetal thymocyte progenitor homeostasis and differentiation to CD4+CD8+ double-positive cell.	BMP2 BMP4	1.27e-05	3	72	2	24240189
Pubmed	Using EC and ES cell culture to study early development: recent observations on Indian hedgehog and Bmps.	BMP2 BMP4	1.27e-05	3	72	2	9853822
Pubmed	Bone morphogenetic protein antagonist gremlin 1 is widely expressed by cancer-associated stromal cells and can promote tumor cell proliferation.	BMP2 BMP4	1.27e-05	3	72	2	17003113
Pubmed	The multifaceted effects of agmatine on functional recovery after spinal cord injury through Modulations of BMP-2/4/7 expressions in neurons and glial cells.	BMP2 BMP4	1.27e-05	3	72	2	23349763
Pubmed	Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.	PLEKHG1 PSMD12 CDK1 DOT1L PLEKHA7 SNX5	1.40e-05	251	72	6	29778605
Pubmed	Dual role for Islet-1 in promoting striatonigral and repressing striatopallidal genetic programs to specify striatonigral cell identity.	CALB1 SLC35D3 PLXND1	1.46e-05	23	72	3	24351932
Pubmed	Shh signaling within the dental epithelium is necessary for cell proliferation, growth and polarization.	BMP2 BMP4 CALB1	1.67e-05	24	72	3	12403705
Pubmed	Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.	CLPP PLEKHG1 INPP5B BAG3 PSMD12 ECPAS PLEKHA7 UTRN ARID3B NUP205	1.87e-05	916	72	10	32203420
Pubmed	Multiple developmental programs are altered by loss of Zic1 and Zic4 to cause Dandy-Walker malformation cerebellar pathogenesis.	BMP2 BMP4 CALB1	1.89e-05	25	72	3	21307096
Pubmed	Ubiquitin-assisted phase separation of dishevelled-2 promotes Wnt signalling.	AP1B1 AP2B1 MARK3 BAG3 CDK1	2.18e-05	161	72	5	36398662
Pubmed	Novel regulators of bone formation: molecular clones and activities.	BMP2 BMP4	2.53e-05	4	72	2	3201241
Pubmed	Repulsive guidance molecule (RGMa), a DRAGON homologue, is a bone morphogenetic protein co-receptor.	BMP2 BMP4	2.53e-05	4	72	2	15975920
Pubmed	Skeletal abnormalities in doubly heterozygous Bmp4 and Bmp7 mice.	BMP2 BMP4	2.53e-05	4	72	2	9664686
Pubmed	Role of activation of PIP5Kgamma661 by AP-2 complex in synaptic vesicle endocytosis.	AP1B1 AP2B1	2.53e-05	4	72	2	17290217
Pubmed	A new function of BMP4: dual role for BMP4 in regulation of Sonic hedgehog expression in the mouse tooth germ.	BMP2 BMP4	2.53e-05	4	72	2	10704389
Pubmed	BMPs: time to murder and create?	BMP2 BMP4	2.53e-05	4	72	2	10204532
Pubmed	Immunohistochemical localization of bone morphogenetic proteins (BMPs) 2, 4, 6, and 7 during induced heterotopic bone formation.	BMP2 BMP4	2.53e-05	4	72	2	17262821
Pubmed	BMP signaling in the human fetal ovary is developmentally regulated and promotes primordial germ cell apoptosis.	BMP2 BMP4	2.53e-05	4	72	2	20506112
Pubmed	Alteration in the expression of bone morphogenetic protein-2,3,4,5 mRNA during pathogenesis of cleft palate in BALB/c mice.	BMP2 BMP4	2.53e-05	4	72	2	10716617
Pubmed	Antagonistic effects of bone morphogenetic protein-4 and -7 on renal mesangial cell proliferation induced by aldosterone through MAPK activation.	BMP2 BMP4	2.53e-05	4	72	2	17244894
Pubmed	Immunoexpression of BMP-2 and BMP-4 and their receptors, BMPR-IA and BMPR-II, in ameloblastomas and adenomatoid odontogenic tumors.	BMP2 BMP4	2.53e-05	4	72	2	27780042
Pubmed	Pleiotrophin expression during odontogenesis.	BMP2 BMP4	2.53e-05	4	72	2	22382872
Pubmed	Changes in homeobox-containing gene expression during ectopic bone formation induced by bone morphogenetic protein.	BMP2 BMP4	2.53e-05	4	72	2	7911662
Pubmed	A heart-hand syndrome gene: Tfap2b plays a critical role in the development and remodeling of mouse ductus arteriosus and limb patterning.	BMP2 BMP4	2.53e-05	4	72	2	21829553
Pubmed	Identification of a novel vertebrate cyclin: cyclin B3 shares properties with both A- and B-type cyclins.	CCNB3 CDK1	2.53e-05	4	72	2	8313904
Pubmed	Comparative analysis of neural crest cell death, migration, and function during vertebrate embryogenesis.	BMP2 BMP4	2.53e-05	4	72	2	14699574
Pubmed	Shh, Bmp-2, Bmp-4 and Fgf-8 are associated with initiation and patterning of mouse tongue papillae.	BMP2 BMP4	2.53e-05	4	72	2	10330496
Pubmed	Rescue of cleft palate in Msx1-deficient mice by transgenic Bmp4 reveals a network of BMP and Shh signaling in the regulation of mammalian palatogenesis.	BMP2 BMP4	2.53e-05	4	72	2	12163415
Pubmed	Endogenous Wnt/beta-catenin signaling is required for cardiac differentiation in human embryonic stem cells.	BMP4 WNT8A	2.53e-05	4	72	2	20559569
Pubmed	BMPER, a novel endothelial cell precursor-derived protein, antagonizes bone morphogenetic protein signaling and endothelial cell differentiation.	BMP2 BMP4	2.53e-05	4	72	2	12897139
Pubmed	Activation of BMP-Smad1/5/8 signaling promotes survival of retinal ganglion cells after damage in vivo.	BMP2 BMP4	2.53e-05	4	72	2	22701694
Pubmed	Cyclic dermal BMP signalling regulates stem cell activation during hair regeneration.	BMP2 BMP4	2.53e-05	4	72	2	18202659
Interaction	ARF6 interactions	HK1 AP1B1 AP2B1 MARK3 INPP5B ITGA6 RICTOR CDK1 ECPAS PLEKHA7 SNX5	5.06e-06	584	70	11	int:ARF6
Cytoband	5q23.3	SLC27A6 FNIP1	2.18e-04	14	72	2	5q23.3
Cytoband	11q23.2	TTC12 NXPE1	3.65e-04	18	72	2	11q23.2
Cytoband	1p22.3	DNAI3 SPATA1	5.49e-04	22	72	2	1p22.3
GeneFamily	Components of oligomeric golgi complex	COG2 COG7	2.08e-04	8	50	2	493
GeneFamily	Bone morphogenetic proteins\|Astacins	BMP2 BMP4	4.06e-04	11	50	2	455
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-3m-Mesenchymal\|3m / Sample Type, Dataset, Time_group, and Cell type.	TYR BMP4 C6orf118 TRPM3 TTC29 DRC1 CCDC160 DNAI3	1.24e-09	200	72	8	ce012d738cbec1afdd6af0e10e94b2b6c17b036e
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-3m-Mesenchymal-Cilia-bearing_cell\|3m / Sample Type, Dataset, Time_group, and Cell type.	BMP4 C6orf118 TRPM3 TTC29 DRC1 CCDC160 DNAI3 DNAH9	1.24e-09	200	72	8	0d14a950172a56b11fdebee8f4e13b0c10e0d592
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-3m-Mesenchymal-BMP_responsible_cell\|3m / Sample Type, Dataset, Time_group, and Cell type.	TYR BMP4 C6orf118 CALB1 TRPM3 DRC1 CCDC160 DNAI3	1.24e-09	200	72	8	a4b52466b6426a835655b5fe7487e15aea816e14
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-10\|TCGA-Brain / Sample_Type by Project: Shred V9	TTC29 TTC12 DRC1 CFAP57 DNAI3 PLEKHA7 DNAH9	1.21e-08	171	72	7	74be8d3bf6b99e2d734635a8b1a7c41e8c596959
ToppCell	NS-critical-d_16-33-Epithelial-Ciliated\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	C6orf118 TTC29 DRC1 ANKRD18A CFAP57 DNAI3 DNAH9	2.16e-08	186	72	7	76033438426d8f9c72cd6691a7baf92104c9f03d
ToppCell	Bronchus_Control_(B.)-Epithelial-TX-Ciliated\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	C6orf118 TTC29 DRC1 ANKRD18A CFAP57 DNAI3 DNAH9	3.56e-08	200	72	7	6a2ccc71a0cbe04a542c379b28b5006de53981c3
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Mesenchymal-BMP_responsible_cell\|6m / Sample Type, Dataset, Time_group, and Cell type.	TYR BMP4 C6orf118 TRPM3 DRC1 CCDC160 DNAI3	3.56e-08	200	72	7	5fb90118d3abc28d72bc483e68317255090a04c7
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Mesenchymal-Cilia-bearing_cell\|6m / Sample Type, Dataset, Time_group, and Cell type.	TYR C6orf118 TRPM3 TTC29 DRC1 DNAI3 DNAH9	3.56e-08	200	72	7	177f9ad8dd8635394c575a2b30140184df0bd51e
ToppCell	wk_08-11-Epithelial-Proximal_epithelial-Deuterosomal\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	3.63e-07	172	72	6	08ad76412c9cc3504141797b44b88478ced87476
ToppCell	Fetal_29-31_weeks-Epithelial-ciliated_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	C6orf118 TTC29 CCDC175 DRC1 DNAI3 DNAH9	4.43e-07	178	72	6	de5d50d7ca9ee9eb62f50c88a0c6d47f0694b2e6
ToppCell	TCGA-Endometrium-Primary_Tumor-Endometrial_Adenocarcinoma-Endometrioid-4\|TCGA-Endometrium / Sample_Type by Project: Shred V9	C6orf118 TTC29 CCDC160 CFAP57 DNAI3 DNAH9	4.89e-07	181	72	6	51d91b923920463245e95d65c6a5197e21d34d73
ToppCell	Fetal_29-31_weeks-Epithelial-ciliated_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	4.89e-07	181	72	6	dfce05bd472f67e6e2bb60ebd6fd34f0a9aeeca6
ToppCell	Adult-Epithelial-ciliated_cell-D122\|Adult / Lineage, Cell type, age group and donor	TYR C6orf118 TTC29 DRC1 CFAP57 DNAH9	5.05e-07	182	72	6	7ded554a4b441e6496db673ba206c0d76ccad7d9
ToppCell	NS-moderate-d_16-33-Epithelial-Ciliated\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	5.56e-07	185	72	6	5e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCell	Adult-Epithelial-ciliated_cell-D175\|Adult / Lineage, Cell type, age group and donor	C6orf118 TTC29 CCDC175 DRC1 CFAP57 DNAH9	5.56e-07	185	72	6	30f4980dee6cd5959655f8d74049f3bfb5312611
ToppCell	droplet-Lung-nan-18m-Epithelial-Ciliated_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTC29 SLC35D3 DRC1 CFAP57 DNAI3 DNAH9	5.74e-07	186	72	6	740fd06bcd3b24e6ff2ecf8080f378afc3e95084
ToppCell	NS-moderate-d_07-13-Epithelial-Ciliated\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	5.74e-07	186	72	6	85787ff207f109ec7e3c0f729ba9bda739c2fdc9
ToppCell	18-Distal-Epithelial-Multiciliated_precursor\|Distal / Age, Tissue, Lineage and Cell class	C6orf118 DRC1 CDK1 CFAP57 DNAI3 DNAH9	5.74e-07	186	72	6	58ab1360a1730655a5939295ba05997ac4a2d14e
ToppCell	droplet-Lung-nan-18m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTC29 SLC35D3 DRC1 CFAP57 DNAI3 DNAH9	5.74e-07	186	72	6	5ab43a298d23238b34e898d11decf0ad81d1b14e
ToppCell	18-Distal-Epithelial-Multiciliated_cell\|Distal / Age, Tissue, Lineage and Cell class	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	5.92e-07	187	72	6	8d7fa6b2950898e7f283401808378ba2a41b9651
ToppCell	Ciliated_cells-B-IPF_03\|World / lung cells shred on cell class, cell subclass, sample id	C6orf118 TTC29 ANKRD18A CFAP57 DNAI3 DNAH9	5.92e-07	187	72	6	6fa38dbccca36bc7a4fef46de74c6688f599f421
ToppCell	Fetal_29-31_weeks-Epithelial-ciliated_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	5.92e-07	187	72	6	9e10ed56090d82589bc457788282f664b70ace4b
ToppCell	tumor_Lung-Epithelial_cells-tS3\|tumor_Lung / Location, Cell class and cell subclass	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	6.11e-07	188	72	6	26326b4e298e33f9ba393fc632238aa8c54b1ea3
ToppCell	Epithelial-ciliated_cell\|World / Lineage, Cell type, age group and donor	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	6.11e-07	188	72	6	61a459f3fe57e5728efc72637ff2edc2d343492b
ToppCell	Adult-Epithelial-ciliated_cell-D231\|Adult / Lineage, Cell type, age group and donor	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	6.11e-07	188	72	6	34b11f72ca73153d02edcd09b38983ad1a504659
ToppCell	Children_(3_yrs)-Epithelial-ciliated_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	6.30e-07	189	72	6	68a3cf7763d6f9b95d6d6524eff7a16042703f1d
ToppCell	cellseq2-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	6.30e-07	189	72	6	a3cd4c2da4feb9bdcd8957f3e344d095da1367b8
ToppCell	COVID-19-lung-Ciliated\|lung / Disease (COVID-19 only), tissue and cell type	C6orf118 TTC29 CCDC175 DRC1 CFAP57 DNAH9	6.30e-07	189	72	6	27329c4661aebabd19fac7fe5dca263fe99d76f3
ToppCell	cellseq2-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	6.30e-07	189	72	6	93b1026bb1ba759e5704561c9a5de14a30c08894
ToppCell	Nasal_Brush-Epithelial-Ciliated_2\|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	6.50e-07	190	72	6	9ce7df056bfb24d70db4c3c4a2c57d89115de877
ToppCell	facs-Lung-nan-3m-Epithelial-Ciliated_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM3 TTC29 DRC1 CFAP57 DNAI3 DNAH9	6.50e-07	190	72	6	e243b5fbb17b9ec3cc90bbe970c1d30b0fd1c2e1
ToppCell	Nasal_Brush-Epithelial-Ciliated_2\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	6.50e-07	190	72	6	833481ace2800354712e2ce709d5cdfd0aed3d42
ToppCell	cellseq2-Epithelial-Epithelial_Airway\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	6.50e-07	190	72	6	17829f4de31b3d9e4d71ba4817d18842aa699773
ToppCell	facs-Lung-nan-3m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM3 TTC29 DRC1 CFAP57 DNAI3 DNAH9	6.50e-07	190	72	6	fe844559b95832845d2e8d3ab4b57e3d558bc372
ToppCell	356C-Epithelial_cells-Epithelial-F_(Ciliated)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	6.70e-07	191	72	6	8a5a2188b13ef4bbfd626a42565566708a751c1b
ToppCell	356C-Epithelial_cells-Epithelial-F_(Ciliated)\|356C / Donor, Lineage, Cell class and subclass (all cells)	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	6.70e-07	191	72	6	e314dd8f1a841cab847ae3703bedfe1bc623ac61
ToppCell	nucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	6.70e-07	191	72	6	e417bf491f8b8d7838a61f7f4f6b1740ba97aa3f
ToppCell	nucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	6.70e-07	191	72	6	9d31c8424d35bdc0c27188b68bfd0f731af3600b
ToppCell	nucseq-Epithelial-Epithelial_Airway\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	6.70e-07	191	72	6	1c528f72c9ef3ef3a850b05e4a9715190832270c
ToppCell	LAM-Epithelial-AirwayEpi\|LAM / Condition, Lineage and Cell class	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	6.90e-07	192	72	6	7404fc65be3b7bd09447725b43fa31819004dfee
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	C6orf118 TTC29 DRC1 ANKRD18A CCDC160 DNAI3	6.90e-07	192	72	6	1b6cac8156e608061e1405e36e18d185b6fa8f6f
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	7.12e-07	193	72	6	e1b76102f812c433195d1e8811fdd3293a7bc22e
ToppCell	wk_15-18-Epithelial-Proximal_epithelial\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	7.34e-07	194	72	6	b0477583301dc6d9767b667bd2f8f94fbfaa6f81
ToppCell	cellseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	7.56e-07	195	72	6	d8bf15aa7cdbc5f29b58e1e6cff76c257f0ea12e
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-Ciliated\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	7.56e-07	195	72	6	cfcf554b436083179dea1d6fd6e3a800ea2430fe
ToppCell	NS-critical-LOC-Epithelial-Ciliated\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	7.56e-07	195	72	6	34e37cff4849696ca4ba5dd8fd2cf98fed8bc912
ToppCell	moderate-Epithelial-Ciliated\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	7.56e-07	195	72	6	3486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	7.56e-07	195	72	6	e22ca35bea06aa95ff2cc771632969f5e7229ffc
ToppCell	moderate-Epithelial-Ciliated\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	7.56e-07	195	72	6	e80f5cdf0b18066b3e6c2f5452e58f101c67932c
ToppCell	cellseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	7.56e-07	195	72	6	e7f069f557a59ee7b502ff82ad4c9f47fa619ba8
ToppCell	critical-Epithelial-Ciliated\|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	7.79e-07	196	72	6	27b855c6e1ae44f16db998cf0e81bd686b9cee7e
ToppCell	BAL-Severe-Epithelial-Epithelial-Ciliated\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	7.79e-07	196	72	6	686a5a0ddb00929842c1c98445c59edfcc9a8a04
ToppCell	BAL-Severe-Epithelial-Epithelial-Ciliated-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	7.79e-07	196	72	6	67aefc480714e4b8c9ae53c036efdc07ec6f94af
ToppCell	BAL-Severe-Epithelial-Epithelial-Ciliated\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	7.79e-07	196	72	6	ca56311edc6788e032e7635fa69b1e07035202b5
ToppCell	Severe_COVID-19-Epithelial-Ciliated\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	7.79e-07	196	72	6	1cdef976a754c90d18b6149d367bd64e6e99b0a9
ToppCell	NS-control-d_0-4-Epithelial-Ciliated\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	7.79e-07	196	72	6	d46ab80554dd3c1cc81e1938ea2acfd5e85c6d2a
ToppCell	BAL-Severe-Epithelial-Epithelial-Ciliated-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	7.79e-07	196	72	6	69f5081e06d84ec1d9695762df801a9d0df1984b
ToppCell	PSB-critical-LOC-Epithelial-Ciliated\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	8.02e-07	197	72	6	6865f4831eb23794fb88a8649d48d497bbae3f44
ToppCell	NS-moderate-d_0-4-Epithelial-Ciliated\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	8.02e-07	197	72	6	71fea4aa6ce96c7693fa94792d08770622873850
ToppCell	proximal-Epithelial-Proximal_Ciliated-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	8.26e-07	198	72	6	69acfdd525c05483f496e54f36762fcbc5521bd4
ToppCell	wk_20-22-Epithelial-Proximal_epithelial\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	8.26e-07	198	72	6	16c54b884500066ade05a406915f9569ca8abdfc
ToppCell	critical-Epithelial-Ciliated\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	8.26e-07	198	72	6	ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCell	proximal-3-Epithelial-Proximal_Ciliated\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	8.26e-07	198	72	6	090e2895f1fb37473d5212b2bed31c15b0745dc4
ToppCell	proximal-Epithelial-Proximal_Ciliated\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	8.26e-07	198	72	6	594b46e811f112d98879b59fdd0cfb068fc07f94
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-Ciliated\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	8.51e-07	199	72	6	b974b495cabbcc3934936cec846c0e2442a70ac3
ToppCell	medial-Epithelial-Ciliated-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	8.51e-07	199	72	6	526002f16bbf61cf086278d45a401cc0b0b757a8
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-1m-Mesenchymal-Cilia-bearing_cell\|1m / Sample Type, Dataset, Time_group, and Cell type.	C6orf118 TRPM3 TTC29 DRC1 DNAI3 DNAH9	8.51e-07	199	72	6	fd91fdc76decd5876d5e914d68134282aba9c4c8
ToppCell	distal-Epithelial-Ciliated-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	8.51e-07	199	72	6	2de1fe124737a6cca4b3805ab3056f9d9d7c16c7
ToppCell	medial-Epithelial-Ciliated\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	8.51e-07	199	72	6	a2daa42b100c422dc8c04fb7d2ebf54293eef574
ToppCell	distal-Epithelial-Ciliated\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	8.51e-07	199	72	6	18ca031cfe702afb9bf94e03c0f3680c38e7599e
ToppCell	medial-2-Epithelial-Ciliated\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	8.51e-07	199	72	6	c02f04a5aa79ee0cf427f6e94b93ceab38ebbcd7
ToppCell	proximal-Epithelial-Ciliated\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	8.51e-07	199	72	6	9700f06e51ddca85e482b4f9bd4a79bfcd3cfb76
ToppCell	proximal-3-Epithelial-Ciliated\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	8.51e-07	199	72	6	1188afad6fd5f01f9aeba225f611f38b237dd2c9
ToppCell	distal-3-Epithelial-Ciliated\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	8.51e-07	199	72	6	7e5f29f4ec1fea92f2c0064eea151d2d474ef904
ToppCell	distal-Epithelial-Ciliated-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	8.51e-07	199	72	6	6ce0df4a6f4d9353919e26ffab97c9ec89911da6
ToppCell	proximal-Epithelial-Ciliated-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	8.51e-07	199	72	6	2e8ace105c4e2405baa06d953e52888b54e2d055
ToppCell	distal-2-Epithelial-Ciliated\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	8.51e-07	199	72	6	97b66b82c76c7bc1fcd7da7b94dd2aa2d4d70a60
ToppCell	Biopsy_Control_(H.)-Epithelial-Ciliated\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	8.76e-07	200	72	6	9ae434c78e08adf95da49c85616e3ca72d1227bf
ToppCell	Bronchial-10x5prime-Epithelial-Epi_airway_ciliated\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	8.76e-07	200	72	6	52aef65f01b06cd98056f17977efe525aee6eb6f
ToppCell	Bronchial-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	8.76e-07	200	72	6	55c148238d5c80c1faa3428a917ae8075be2c145
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_ciliated\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	8.76e-07	200	72	6	31d75c26055177d656df1fbb10b764cebd61e122
ToppCell	Biopsy_Other_PF-Epithelial-Ciliated\|Biopsy_Other_PF / Sample group, Lineage and Cell type	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	8.76e-07	200	72	6	721371698bce8890853fb6b6b01a2c20293b39e9
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_ciliated-Ciliated\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	C6orf118 TTC29 CCDC175 DRC1 CFAP57 DNAH9	8.76e-07	200	72	6	926a7ea94b5908aebf103893ea83ce9d25285b65
ToppCell	Parenchymal-10x5prime-Epithelial-Epi_airway_ciliated\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	8.76e-07	200	72	6	85c98da55f7cd4ffdf9d309b56c8cc5d43f3c04c
ToppCell	Biopsy_Control_(H.)-Epithelial-Differentiating_Ciliated\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	C6orf118 DRC1 CDK1 CFAP57 DNAI3 DNAH9	8.76e-07	200	72	6	a552a99f5e4fa00dfb7775e5a3e1f62f1530d104
ToppCell	Biopsy_IPF-Epithelial-Ciliated\|Biopsy_IPF / Sample group, Lineage and Cell type	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	8.76e-07	200	72	6	bb8c99156e547a8eb6599b6b6bc3c66bf77af7f8
ToppCell	Parenchymal-10x3prime_v2-Epithelial-Epi_airway_ciliated\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	8.76e-07	200	72	6	5abd6d81e1cc354484ae693fcd708d78926e75b5
ToppCell	Tracheal-10x3prime_v2-Epithelial-Epi_airway_ciliated\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	8.76e-07	200	72	6	7cb3e3bd9e851ccb096e0a3471819471d85ebace
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	8.76e-07	200	72	6	e1dce91c6c531bb212002a14705e496d77ad3490
ToppCell	Parenchymal-10x3prime_v2-Epithelial-Epi_airway_ciliated-Ciliated\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	8.76e-07	200	72	6	9c9d2b0276c7b0709c2eeeb0673a2f58106fb14e
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial-Ciliated\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	8.76e-07	200	72	6	f1a49bc818054fb0734d3b84725ee6487b034567
ToppCell	Parenchyma_COVID-19-Epithelial-TX-Ciliated\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	8.76e-07	200	72	6	d7ae09189cf0b7e2f7e7fc6b0921975b75aa7d62
ToppCell	Parenchymal-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	8.76e-07	200	72	6	12bc7d95c4166d12487081a76d210b7abe5991b0
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-Ciliated\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	8.76e-07	200	72	6	ddd39b754bfaa98249d497dfb7e97ec58617a11a
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_ciliated\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	C6orf118 TTC29 CCDC175 DRC1 CFAP57 DNAH9	8.76e-07	200	72	6	06ce6e03498ba38ef6a06eaf2731e3b2eeda59eb
ToppCell	Parenchyma_Control_(B.)-Epithelial-TX-Ciliated\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	8.76e-07	200	72	6	a521cf837cadf280505ff9d7e641a205af7d6513
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-Ciliated-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	8.76e-07	200	72	6	918b576fd9491d23c2bb9d663fa5fb3505cb1c7e
ToppCell	Tracheal-10x3prime_v2-Epithelial-Epi_airway_ciliated-Ciliated\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	8.76e-07	200	72	6	8441e289377215a6877640946fe3f6de1f456502
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial-Ciliated-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	C6orf118 TTC29 DRC1 CFAP57 DNAI3 DNAH9	8.76e-07	200	72	6	cf59110547cc66b5f4a2999735336b0309ba9b0d
ToppCell	Ciliated_cells-B-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	C6orf118 SLC35D3 CCDC175 DNAI3 DNAH9	6.95e-06	164	72	5	fd30c55d0d75ef8b9396435d836187168095152b
Drug	mantATP	CLPP TGFBRAP1 GSTCD DNAH9	3.99e-06	35	70	4	CID000123756
Drug	2-allylcyclohexen-1-ol	TYR GSTCD	9.32e-06	2	70	2	CID012755878
Disease	otosclerosis (is_implicated_in)	BMP2 BMP4	7.80e-05	6	68	2	DOID:12185 (is_implicated_in)
Disease	Marfan syndrome (implicated_via_orthology)	BMP2 BMP4	2.33e-04	10	68	2	DOID:14323 (implicated_via_orthology)
Disease	tooth agenesis (is_implicated_in)	BMP2 BMP4	2.33e-04	10	68	2	DOID:0050591 (is_implicated_in)
Disease	Global developmental delay	BMP4 HK1 AP1B1 TRPM3	2.57e-04	133	68	4	C0557874
Disease	juvenile polyposis syndrome (implicated_via_orthology)	BMP2 BMP4	4.02e-04	13	68	2	DOID:0050787 (implicated_via_orthology)
Disease	Kartagener syndrome (implicated_via_orthology)	AP1B1 DRC1	4.68e-04	14	68	2	DOID:0050144 (implicated_via_orthology)
Disease	mitochondrial heteroplasmy measurement	BMP2 SNX5 NUP205	5.50e-04	69	68	3	EFO_0600008
Disease	lateral occipital cortex volume measurement	BRINP1 UTRN	6.96e-04	17	68	2	EFO_0010311
Disease	macula measurement	TYR FAT1 C6orf118 PLEKHA7	9.64e-04	189	68	4	EFO_0008375
Disease	cortical thickness	PLEKHG1 BMP2 BMP4 SLC27A6 MARK3 PLXND1 CFAP57 PLEKHA7 RUFY1	9.99e-04	1113	68	9	EFO_0004840
Disease	eye color	TYR HK1 NUP205	1.19e-03	90	68	3	EFO_0003949
Disease	Immunologic Deficiency Syndromes	C8A MYSM1	1.28e-03	23	68	2	C0021051
Disease	prostate carcinoma (is_marker_for)	BMP2 BMP4	1.28e-03	23	68	2	DOID:10286 (is_marker_for)
Disease	gamma-linolenic acid measurement	DOT1L DAGLA	1.40e-03	24	68	2	EFO_0007762
Disease	lung small cell carcinoma (is_implicated_in)	FAT1 RICTOR	1.90e-03	28	68	2	DOID:5409 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
ILDLYMLYKLVTEKG	ARID3B	246	Q8IVW6
KLLLNEDDYLIKAVY	EPC2	161	Q52LR7
AEYASLMEILYTLKE	COG7	541	P83436
ERNKELMKEYNYLKE	ANKRD18A	591	Q8IVF6
DNLELKKLVYLYLMN	AP2B1	61	P63010
YEYILVIDKAKMESL	C8A	351	P07357
LDFQDLELKYLLQKM	BRINP1	481	O60477
LELKYLLQKMDSRLY	BRINP1	486	O60477
LILLKYMYSDEIDLE	BTBD6	191	Q96KE9
NMELSEKYKLDKESY	ERP29	101	P30040
DLMNILYDKDHYKLA	GTPBP4	81	Q9BZE4
DNLELKKLVYLYLMN	AP1B1	61	Q10567
LKLAMENYVLIDYDT	DOT1L	51	Q8TEK3
AELKMDYESYLELEK	DNAI3	856	Q8IWG1
MLYLDENEKVVLKNY	BMP2	371	P12643
ISMLYLDEYDKVVLK	BMP4	381	P12644
TLYLAVKLVDLYLMK	CCNB3	1181	Q8WWL7
LLKALYTYESKMAFL	NUP205	1546	Q92621
DYLETKLYEMEILAA	FAT1	211	Q14517
ILQKLNMKSYEEYKL	MSS51	61	Q4VC12
EYQLRLKDMNYSEKI	CFAP57	716	Q96MR6
INEYKEDPKLLSMAY	ECPAS	406	Q5VYK3
LEYYTSIMKELLVDL	PLXND1	1456	Q9Y4D7
DLYDYMNSLKELLKI	LACTB2	176	Q53H82
IAYHLLKDYDMALKL	NAA16	156	Q6N069
EVAMLYPELYKDLLK	ATP9A	901	O75110
LEEYSKLNYLDILMR	ITGA6	1001	P23229
EENTEKLKLKYYNLM	PSMD12	216	O00232
KIDKYLYAMRLSDET	HK1	21	P19367
MKALSYASLDKEDLL	RICTOR	1381	Q6R327
LEYLNNRMKKVEDYE	DRC1	256	Q96MC2
NLLYYSLDEDSKIMI	CAMK1	146	Q14012
TMKELYDLGLKLAKY	LIG4	511	P49917
LLEIESMELNKLYYL	CCDC175	91	P0C221
LQELYFKSKMLSEYL	FNIP1	1111	Q8TF40
TKLAEYTDLMLKLFD	CALB1	141	P05937
NVLLKEEMKSYYELE	CCDC160	256	A6NGH7
DLLKKVKDEYELYMA	C6orf118	286	Q5T5N4
NLMYLKQILYLLEKF	DDX12P	456	Q92771
KMKYDEITATYLLLG	MARK3	351	P27448
KYLDLKNSQEMLRYK	DAGLA	276	Q9Y4D2
KKLIEEKDFQMLYAY	INPP5B	541	P32019
QKYEDMLSLLEKYET	DNAH9	646	Q9NYC9
MLSLLEKYETRLYED	DNAH9	651	Q9NYC9
RDDLELYYKLLKTAM	COG2	46	Q14746
LYYKLLKTAMVELIN	COG2	51	Q14746
YLMIEEYLTKELLAL	BAG3	451	O95817
MKAIKKSLTEEEYLY	GSTCD	1	Q8NEC7
SYKLLSIEEMLIYKD	FPGT	571	O14772
YIHYLIMKDIFKDLN	NXPE1	496	Q8N323
YAVYNEDKLMAKTLL	POTEA	171	Q6S8J7
MSLSKGLLEEKYRYL	UTRN	2961	P46939
YMKKDYLIENEELPS	SLC35D3	401	Q5M8T2
LYLALMQKKLADYLK	RUFY1	211	Q96T51
YLQLKKDLEYLDLKM	PLEKHA7	656	Q6IQ23
YYTDLLQMKLDNLNK	SPDL1	366	Q96EA4
DLELYYKKLLMQLEA	SPATA1	366	Q5VX52
YIKDYMKSINEKLEE	TPT1P8	91	Q9HAU6
LYLIFEFLSMDLKKY	CDK1	76	P06493
EEIMKLKKQLYNIYA	CLPP	196	Q16740
ILKKSYEAALLPLYM	THEMIS	416	Q8N1K5
ARSENLIYTYDKMKL	TGFBRAP1	791	Q8WUH2
AKDYTKALKLLDYVM	TRAPPC11	466	Q7Z392
SYKQDEQLAMKLLTY	TRPM3	736	Q9HCF6
NDSMKEELLKYRSLY	SOGA1	171	O94964
KQPLLMEKEDYHSLY	TYR	511	P14679
DEDLKLTELLRYYML	SNX5	286	Q9Y5X3
TYRLLSDKMLENKEY	TTC29	236	Q8NA56
RAQAYMKLEDYEKAL	TTC12	146	Q9H892
YDNISYEDLKLMVAK	PLEKHG1	661	Q9ULL1
DYLKAKYDQALKIEM	WNT8A	206	Q9H1J5
MKFLLLQQKYLEYLE	WDR26	211	Q9H7D7
LYFMDNLKKSYVLLT	SLC27A6	591	Q9Y2P4
YDQMYNDLLRKDKEL	SSU72	61	Q9NP77
GYSYLLLKELQMKDS	TRAV1-2	86	A0A0B4J238
EKMLLEEEYYLSKKS	MYSM1	66	Q5VVJ2