Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionolfactory receptor activity

OR5B3 OR2AK2 OR8U1 OR6N2 OR2AP1 OR5B2 OR5B17 OR1J4 OR1L1 OR6N1 OR8U8 OR2L2 OR6C1 OR6C75 OR52E8 OR1A1 OR6C6

1.03e-0743116417GO:0004984
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

OR5B3 OR2AK2 OR8U1 OR6N2 OR2AP1 OR5B2 OR5B17 GRID1 GRIN2B CHRM1 IL18R1 OR1J4 CHRM5 OR1L1 OR6N1 OR8U8 OR2L2 MET PTPRB PTPRK OR6C1 OR6C75 OR52E8 OR1A1 ROS1 OR6C6 PLXNA2

1.53e-05135316427GO:0004888
GeneOntologyMolecularFunctionglucan 1,4-alpha-glucosidase activity

MGAM MGAM2

6.70e-0521642GO:0004339
GeneOntologyMolecularFunctionG protein-coupled receptor activity

OR5B3 OR2AK2 OR8U1 OR6N2 OR2AP1 OR5B2 OR5B17 CHRM1 OR1J4 CHRM5 OR1L1 OR6N1 OR8U8 OR2L2 OR6C1 OR6C75 OR52E8 OR1A1 OR6C6

1.23e-0488416419GO:0004930
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH7 DNAH1 DNAH6

4.05e-04181643GO:0008569
GeneOntologyMolecularFunctionaminopeptidase activity

TPP2 XPNPEP2 DPP8 ERAP2

4.22e-04431644GO:0004177
GeneOntologyMolecularFunctioncytoskeletal motor activity

CENPE MYO7A DNAH7 DNAH1 MYO3B DNAH6

4.32e-041181646GO:0003774
GeneOntologyMolecularFunctionodorant binding

OR5B3 OR8U1 OR6N2 OR5B2 OR5B17 OR8U8

6.39e-041271646GO:0005549
GeneOntologyMolecularFunctionalpha-1,4-glucosidase activity

MGAM MGAM2

6.60e-0451642GO:0004558
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception of smell

OR5B3 OR2AK2 OR8U1 OR6N2 OR2AP1 OR5B2 OR5B17 OR1J4 OR1L1 OR6N1 OR8U8 OR2L2 OR6C1 OR6C75 OR52E8 OR1A1 OR6C6

6.71e-0843216417GO:0050911
GeneOntologyBiologicalProcesssensory perception of smell

OR5B3 OR2AK2 OR8U1 OR6N2 OR2AP1 OR5B2 OR5B17 OR1J4 OR1L1 OR6N1 OR8U8 OR2L2 OR6C1 OR6C75 OR52E8 OR1A1 OR6C6

1.92e-0746516417GO:0007608
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception

OR5B3 OR2AK2 OR8U1 OR6N2 OR2AP1 OR5B2 OR5B17 GRIN2B OR1J4 OR1L1 OR6N1 OR8U8 OR2L2 OR6C1 OR6C75 OR52E8 OR1A1 SCN10A OR6C6

2.03e-0758216419GO:0050906
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception

OR5B3 OR2AK2 OR8U1 OR6N2 OR2AP1 OR5B2 OR5B17 OR1J4 OR1L1 OR6N1 OR8U8 OR2L2 OR6C1 OR6C75 OR52E8 OR1A1 OR6C6

3.46e-0748516417GO:0050907
GeneOntologyBiologicalProcessdetection of chemical stimulus

OR5B3 OR2AK2 OR8U1 OR6N2 OR2AP1 OR5B2 OR5B17 OR1J4 OR1L1 OR6N1 OR8U8 OR2L2 OR6C1 OR6C75 OR52E8 OR1A1 OR6C6

1.01e-0652416417GO:0009593
GeneOntologyBiologicalProcessdetection of stimulus

OR5B3 OR2AK2 OR8U1 OR6N2 PDE6B OR2AP1 OR5B2 OR5B17 GRIN2B OR1J4 OR1L1 OR6N1 OR8U8 OR2L2 OR6C1 OR6C75 OR52E8 OR1A1 SCN10A OR6C6

1.26e-0672216420GO:0051606
GeneOntologyBiologicalProcesssensory perception of chemical stimulus

OR5B3 OR2AK2 OR8U1 OR6N2 OR2AP1 OR5B2 OR5B17 OR1J4 OR1L1 OR6N1 OR8U8 OR2L2 OR6C1 OR6C75 OR52E8 OR1A1 OR6C6

1.81e-0654716417GO:0007606
GeneOntologyBiologicalProcesssensory perception

OR5B3 OR2AK2 OR8U1 OR6N2 PDE6B MYO7A OR2AP1 OR5B2 OR5B17 GRIN2B OR1J4 OR1L1 OR6N1 OR8U8 OR2L2 OR6C1 OR6C75 MYO3B OR52E8 OR1A1 SCN10A MME OR6C6

1.39e-05107216423GO:0007600
GeneOntologyCellularComponentaxonemal dynein complex

DNAH7 DNAH1 DNAI4 DNAH6

4.36e-05251674GO:0005858
GeneOntologyCellularComponentinner dynein arm

DNAH7 DNAH1 DNAH6

5.77e-05101673GO:0036156
DomainOlfact_rcpt

OR5B3 OR2AK2 OR8U1 OR6N2 OR2AP1 OR5B2 OR5B17 OR1J4 OR1L1 OR6N1 OR8U8 OR2L2 OR6C1 OR6C75 OR52E8 OR1A1 OR6C6

6.41e-0839316317IPR000725
DomainGPCR_Rhodpsn_7TM

OR5B3 OR2AK2 OR8U1 OR6N2 OR2AP1 OR5B2 OR5B17 CHRM1 OR1J4 CHRM5 OR1L1 OR6N1 OR8U8 OR2L2 OR6C1 OR6C75 OR52E8 OR1A1 OR6C6

6.38e-0667016319IPR017452
Domain7tm_1

OR5B3 OR2AK2 OR8U1 OR6N2 OR2AP1 OR5B2 OR5B17 CHRM1 OR1J4 CHRM5 OR1L1 OR6N1 OR8U8 OR2L2 OR6C1 OR6C75 OR52E8 OR1A1 OR6C6

7.40e-0667716319PF00001
DomainG_PROTEIN_RECEP_F1_1

OR5B3 OR2AK2 OR8U1 OR6N2 OR2AP1 OR5B2 OR5B17 CHRM1 OR1J4 CHRM5 OR1L1 OR6N1 OR8U8 OR2L2 OR6C1 OR6C75 OR52E8 OR1A1 OR6C6

8.73e-0668516319PS00237
DomainG_PROTEIN_RECEP_F1_2

OR5B3 OR2AK2 OR8U1 OR6N2 OR2AP1 OR5B2 OR5B17 CHRM1 OR1J4 CHRM5 OR1L1 OR6N1 OR8U8 OR2L2 OR6C1 OR6C75 OR52E8 OR1A1 OR6C6

9.88e-0669116319PS50262
DomainGPCR_Rhodpsn

OR5B3 OR2AK2 OR8U1 OR6N2 OR2AP1 OR5B2 OR5B17 CHRM1 OR1J4 CHRM5 OR1L1 OR6N1 OR8U8 OR2L2 OR6C1 OR6C75 OR52E8 OR1A1 OR6C6

1.01e-0569216319IPR000276
DomainPAS_9

KCNH7 KCNH6 PASK

7.49e-05101633PF13426
Domain-

ATR GPS1 NAPG SRP68 TTC19 LRPPRC SEL1L2 ZC3H7B ANAPC7

8.71e-0520716391.25.40.10
DomainPAS

KCNH7 SIM2 KCNH6 PASK

2.11e-04341634PS50112
DomainPAS

KCNH7 SIM2 KCNH6 PASK

2.11e-04341634IPR000014
DomainTPR-like_helical_dom

ATR GPS1 NAPG SRP68 TTC19 LRPPRC SEL1L2 ZC3H7B ANAPC7

2.13e-042331639IPR011990
DomainDynein_heavy_chain_D4_dom

DNAH7 DNAH1 DNAH6

2.21e-04141633IPR024317
DomainDynein_HC_stalk

DNAH7 DNAH1 DNAH6

2.21e-04141633IPR024743
DomainDynein_heavy_dom-2

DNAH7 DNAH1 DNAH6

2.21e-04141633IPR013602
DomainDHC_N2

DNAH7 DNAH1 DNAH6

2.21e-04141633PF08393
DomainMT

DNAH7 DNAH1 DNAH6

2.21e-04141633PF12777
DomainAAA_8

DNAH7 DNAH1 DNAH6

2.21e-04141633PF12780
DomainK_chnl_volt-dep_ERG

KCNH7 KCNH6

2.26e-0431632IPR003967
DomainDHC_fam

DNAH7 DNAH1 DNAH6

2.75e-04151633IPR026983
DomainDynein_heavy

DNAH7 DNAH1 DNAH6

2.75e-04151633PF03028
DomainDynein_heavy_dom

DNAH7 DNAH1 DNAH6

2.75e-04151633IPR004273
DomainGal_mutarotase_N

MGAM MGAM2

4.49e-0441632IPR031727
DomainNtCtMGAM_N

MGAM MGAM2

4.49e-0441632PF16863
DomainKIND_dom

FRMPD2 KNDC1

7.44e-0451632IPR011019
DomainKIND

FRMPD2 KNDC1

7.44e-0451632SM00750
DomainMusac_Ach_rcpt

CHRM1 CHRM5

7.44e-0451632IPR000995
DomainCreatin/AminoP/Spt16_NTD

XPNPEP2 SUPT16H

7.44e-0451632IPR029149
Domain-

XPNPEP2 SUPT16H

7.44e-04516323.40.350.10
DomainKIND

FRMPD2 KNDC1

7.44e-0451632PS51377
DomainKinase-like_dom

ATR SPEG MET PASK CSNK1D CSNK1E MYO3B KNDC1 ROS1 DCLK2 EIF2AK1 DNM2 CDK4

9.60e-0454216313IPR011009
DomainDUF3669_Znf

ZNF783 ZNF398

1.11e-0361632IPR022137
DomainDUF3669

ZNF783 ZNF398

1.11e-0361632PF12417
DomainGlyco_hydro_31_AS

MGAM MGAM2

1.11e-0361632IPR030458
DomainPAS-assoc_C

KCNH7 SIM2 KCNH6

1.15e-03241633IPR000700
DomainPAS

SIM2 KCNH6 PASK

1.30e-03251633PF00989
DomainPAS_fold

SIM2 KCNH6 PASK

1.30e-03251633IPR013767
DomainPAC

KCNH7 SIM2 KCNH6

1.46e-03261633IPR001610
DomainPAC

KCNH7 SIM2 KCNH6

1.46e-03261633PS50113
DomainPAC

KCNH7 SIM2 KCNH6

1.46e-03261633SM00086
DomainGlyco_hydro_31

MGAM MGAM2

1.54e-0371632IPR000322
DomainGlyco_hydro_31

MGAM MGAM2

1.54e-0371632PF01055
DomainGLYCOSYL_HYDROL_F31_1

MGAM MGAM2

1.54e-0371632PS00129
DomainProtein_kinase_ATP_BS

SPEG MET PASK CSNK1D CSNK1E MYO3B ROS1 DCLK2 EIF2AK1 CDK4

1.86e-0337916310IPR017441
DomainPH-BEACH_dom

WDFY4 LRBA

2.05e-0381632IPR023362
Domain-

WDFY4 LRBA

2.05e-03816322.30.29.40
DomainTrefoil

MGAM MGAM2

2.05e-0381632PF00088
DomainPH_BEACH

WDFY4 LRBA

2.05e-0381632PS51783
DomainFN3_dom

SPEG KIAA0319L PTPRB PTPRK TRIM9 LRFN5 ROS1

2.43e-032091637IPR003961
DomainPeptidase_S8_His-AS

TPP2 PCSK4

2.62e-0391632IPR022398
DomainPept_M24

XPNPEP2 SUPT16H

2.62e-0391632IPR000994
DomainPeptidase_S8_Ser-AS

TPP2 PCSK4

2.62e-0391632IPR023828
DomainBEACH

WDFY4 LRBA

2.62e-0391632PS50197
DomainBeach

WDFY4 LRBA

2.62e-0391632PF02138
Domain-

WDFY4 LRBA

2.62e-03916321.10.1540.10
DomainP_TREFOIL_2

MGAM MGAM2

2.62e-0391632PS51448
DomainBeach

WDFY4 LRBA

2.62e-0391632SM01026
DomainBEACH_dom

WDFY4 LRBA

2.62e-0391632IPR000409
DomainPeptidase_M24

XPNPEP2 SUPT16H

2.62e-0391632PF00557
Domain-

XPNPEP2 SUPT16H

2.62e-03916323.90.230.10
DomainPD

MGAM MGAM2

2.62e-0391632SM00018
DomainPAS

KCNH7 SIM2 PASK

2.69e-03321633SM00091
PathwayREACTOME_OLFACTORY_SIGNALING_PATHWAY

OR5B3 OR2AK2 OR8U1 OR6N2 OR2AP1 OR5B2 OR5B17 OR1J4 OR1L1 OR6N1 OR8U8 OR2L2 OR6C1 OR6C75 OR52E8 OR1A1 OR6C6

3.90e-0741713317M4072
PathwayREACTOME_SENSORY_PERCEPTION

OR5B3 OR2AK2 OR8U1 OR6N2 PDE6B MYO7A OR2AP1 OR5B2 OR5B17 OR1J4 OR1L1 OR6N1 OR8U8 OR2L2 GPC3 OR6C1 OR6C75 MYO3B OR52E8 OR1A1 OR6C6

5.05e-0763613321M41834
PathwayKEGG_OLFACTORY_TRANSDUCTION

OR5B3 OR2AK2 OR8U1 OR6N2 OR5B17 OR1J4 OR1L1 OR6N1 OR8U8 OR2L2 OR6C1 OR6C75 OR52E8 OR1A1 OR6C6

3.92e-0638913315M14091
Pubmed

Different evolutionary processes shaped the mouse and human olfactory receptor gene families.

OR5B3 OR2AK2 OR8U1 OR6N2 OR2AP1 OR5B2 OR1J4 OR6N1 OR2L2 OR6C1 OR6C75 OR52E8 OR1A1 OR6C6

1.35e-093401681411875048
Pubmed

The olfactory receptor gene superfamily of the mouse.

OR5B3 OR2AK2 OR8U1 OR6N2 OR2AP1 OR5B2 OR1J4 OR6N1 OR2L2 OR6C1 OR6C75 OR52E8 OR1A1 OR6C6

1.35e-093401681411802173
Pubmed

A unified nomenclature for vertebrate olfactory receptors.

OR5B3 OR2AK2 OR8U1 OR6N2 OR2AP1 OR5B2 OR1J4 OR6N1 OR2L2 OR6C1 OR6C75 OR52E8 OR1A1 OR6C6

1.51e-093431681432295537
Pubmed

Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.

OR5B3 OR2AK2 OR8U1 OR6N2 OR2AP1 OR5B2 OR1J4 OR6N1 OR2L2 OR6C1 OR6C75 OR52E8 OR1A1 OR6C6

1.69e-093461681414611657
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

GAPVD1 TBC1D15 TCAF1 HS6ST2 PIGS GPS1 SRP68 CPT1A LRPPRC NAA35 KIDINS220 PTPRK USO1 EIF2S1 EIF4A1 ABCD3 TMED9 TMX3 FUT8 MUL1 CDK4

6.57e-099421682131073040
Pubmed

CRISPR-mediated gene targeting of CK1δ/ε leads to enhanced understanding of their role in endocytosis via phosphoregulation of GAPVD1.

GAPVD1 CSNK1D CSNK1E

1.11e-073168332321936
Pubmed

Primary Ciliary Dyskinesia Associated Disease-Causing Variants in CCDC39 and CCDC40 Cause Axonemal Absence of Inner Dynein Arm Heavy Chains DNAH1, DNAH6, and DNAH7.

DNAH7 DNAH1 DNAH6

1.10e-065168339056782
Pubmed

Proteomic analysis of SET-binding proteins.

TCP1 EIF2S1 CSNK1E DNM2 CDK4

1.61e-0641168517309103
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

CUL3 TPP2 FAM120B TCP1 MYO7A RPS15 SRP68 GRIN2B LRPPRC KIDINS220 AP2A2 SACS USO1 TRIM9 CSNK1D EIF2S1 ABCD3 KNDC1 TMED9 DCLK2 DNAH6 DNM2

1.71e-0614311682237142655
Pubmed

The ATG5 interactome links clathrin-mediated vesicular trafficking with the autophagosome assembly machinery.

GAPVD1 ACADS TCP1 ANKHD1 AP2A2 SACS LTN1 SUPT16H DNM2

1.97e-06230168935449600
Pubmed

SPOP-mediated ubiquitination and degradation of PDK1 suppresses AKT kinase activity and oncogenic functions.

CUL3 CSNK1D CSNK1E

3.82e-067168334353330
Pubmed

Large-scale concatenation cDNA sequencing.

CUL3 NAPG ZNF783 PASK LRPPRC SLITRK2 EIF4A1 EDEM2 MIEF1 FUT8 BAIAP3 ANAPC7 CDK4

4.34e-06568168139110174
Pubmed

A "double adaptor" method for improved shotgun library construction.

CUL3 NAPG ZNF783 PASK LRPPRC SLITRK2 EIF4A1 EDEM2 MIEF1 FUT8 BAIAP3 ANAPC7 CDK4

4.86e-06574168138619474
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

GAPVD1 TBC1D15 GPS1 RPS15 CPT1A ANKHD1 PASK LRPPRC KIDINS220 PTPRK CSNK1D CSNK1E LTN1 RIMOC1 ABCD3 TMX3 FUT8

5.50e-069741681728675297
Pubmed

Hypertonicity-responsive ubiquitin ligase RNF183 promotes Na, K-ATPase lysosomal degradation through ubiquitination of its β1 subunit.

GAPVD1 TBC1D15 TCP1 PIGS SRP68 ANKHD1 KIDINS220 USO1 EIF4A1 ABCD3 LRBA

1.29e-054491681131732153
Pubmed

IKK-Mediated Regulation of the COP9 Signalosome via Phosphorylation of CSN5.

GAPVD1 TBC1D15 TCAF1 GPS1 SRP68 OSBP USO1 LRBA

1.30e-05221168831950832
Pubmed

The human olfactory receptor gene family.

OR5B3 OR2AK2 OR6N2 OR2AP1 OR5B2 OR5B17 OR1J4 OR1L1 OR6N1 OR2L2 OR52E8 OR1A1

1.40e-055411681214983052
Pubmed

Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition.

CUL3 SIM2 PASK KCNG1 CSNK1E MYO3B DCLK2 EIF2AK1 ZC3H7B CDK4

1.46e-053721681022939624
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

GAPVD1 CENPE TCP1 MYO7A OR5B2 UGT1A9 SLC26A9 SRP68 FRY TRIM9 KCNG1 MYO3B ABCD3 ADIPOR2

1.50e-057361681429676528
Pubmed

Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.

PIK3AP1 ARMC9 PRSS23 DTNBP1 ANKHD1 ZDHHC4 USO1 SULF1 MIEF1 EIF2AK1 TMX3 ZC3H7B BAIAP3 MUL1

1.84e-057501681411230166
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

CUL3 GAPVD1 MYO7A PIGS GPS1 SRP68 DPP8 DTNBP1 USP21 EFHC2 LRPPRC AP2A2 SUPT16H ABCD3 EIF2AK1 METTL25 ANAPC7 DNM2 CDK4

2.31e-0513211681927173435
Pubmed

Heme-regulated inhibitor kinase-mediated phosphorylation of eukaryotic translation initiation factor 2 inhibits translation, induces stress granule formation, and mediates survival upon arsenite exposure.

EIF2S1 EIF2AK1

2.32e-052168215684421
Pubmed

Genetic heterogeneity and consanguinity lead to a "double hit": homozygous mutations of MYO7A and PDE6B in a patient with retinitis pigmentosa.

PDE6B MYO7A

2.32e-052168223882135
Pubmed

CK1δ and CK1ε are components of human 40S subunit precursors required for cytoplasmic 40S maturation.

CSNK1D CSNK1E

2.32e-052168224424021
Pubmed

The presence of m1 to m5 receptors in human sclera: evidence of the sclera as a potential site of action for muscarinic receptor antagonists.

CHRM1 CHRM5

2.32e-052168216877267
Pubmed

Autophosphorylation of heme-regulated eukaryotic initiation factor 2α kinase and the role of the modification in catalysis.

EIF2S1 EIF2AK1

2.32e-052168221223507
Pubmed

Regulation of casein kinase I epsilon and casein kinase I delta by an in vivo futile phosphorylation cycle.

CSNK1D CSNK1E

2.32e-05216829632646
Pubmed

Analysis of CD8+ T cell-mediated anti-viral responses in mice with targeted deletions of the M1 or M5 muscarinic cholinergic receptors.

CHRM1 CHRM5

2.32e-052168217286988
Pubmed

The eag family of K+ channels in Drosophila and mammals.

KCNH7 KCNH6

2.32e-052168210414305
Pubmed

Diminished antigen-specific IgG1 and interleukin-6 production and acetylcholinesterase expression in combined M1 and M5 muscarinic acetylcholine receptor knockout mice.

CHRM1 CHRM5

2.32e-052168217586055
Pubmed

Loss of histone lysine methyltransferase EZH2 confers resistance to tyrosine kinase inhibitors in non-small cell lung cancer.

EZH2 MET

2.32e-052168232920200
Pubmed

Oligomerization-induced differential dephosphorylation of c-Met receptor tyrosine kinase.

MET PTPRB

2.32e-052168216101282
Pubmed

Crizotinib in c-MET- or ROS1-positive NSCLC: results of the AcSé phase II trial.

MET ROS1

2.32e-052168231584608
Pubmed

Casein kinase I delta/epsilon phosphorylates topoisomerase IIalpha at serine-1106 and modulates DNA cleavage activity.

CSNK1D CSNK1E

2.32e-052168219043076
Pubmed

MET Oncogene Controls Invasive Growth by Coupling with NMDA Receptor.

GRIN2B MET

2.32e-052168236139568
Pubmed

EZH2-mediated upregulation of ROS1 oncogene promotes oral cancer metastasis.

EZH2 ROS1

2.32e-052168228759046
Pubmed

EZH2/hSULF1 axis mediates receptor tyrosine kinase signaling to shape cartilage tumor progression.

EZH2 SULF1

2.32e-052168236622753
Pubmed

Effects of altered expression and activity levels of CK1δ and ɛ on tumor growth and survival of colorectal cancer patients.

CSNK1D CSNK1E

2.32e-052168225404202
Pubmed

Molecular and biochemical characterization of a novel oxysterol-binding protein (OSBP2) highly expressed in retina.

OSBP OSBP2

2.32e-052168211278871
Pubmed

ROS-1 re-arrangements and c-MET amplifications in adenocarcinoma lung: A tertiary care center study from North India.

MET ROS1

2.32e-052168231361233
Pubmed

USP21 promotes cell proliferation by maintaining the EZH2 level in diffuse large B-cell lymphoma.

EZH2 USP21

2.32e-052168233389794
Pubmed

TFE3-renal carcinoma in an adult patient: a case with strong expression of phosphorylated hepatocyte growth factor (HGFR)/Met.

TFE3 MET

2.32e-052168218930356
Pubmed

An evaluation of polymorphisms in casein kinase 1 delta and epsilon genes in major psychiatric disorders.

CSNK1D CSNK1E

2.32e-052168222981886
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

GAPVD1 TCP1 RPS15 SRP68 SIM2 THOC5 DNAH1 LRPPRC SMPDL3B AP2A2 ERAP2 USO1 CSNK1D EIF2S1 CSNK1E EIF4A1 ABCD3 DNM2

3.67e-0512471681827684187
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH7 DNAH1 DNAH6

3.88e-051416839373155
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

TPP2 TCP1 GPS1 ANKHD1 USO1 EIF2S1 EIF4A1 LTN1 SUPT16H ABCD3 LRBA ZC3H7B CDK4

4.13e-057041681329955894
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

CUL3 DPP8 LRP1B KCNH6 AP2A2 KCNG1 CSNK1D CSNK1E EIF4A1 PLA2G4F PCSK4 DNM2 CDK4

5.96e-057301681334857952
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

TPP2 TBC1D15 TCP1 PIGS SRP68 PIGG CPT1A ANKHD1 MET LRPPRC NAA35 KIDINS220 CSNK1D EIF4A1 RIMOC1 TMED9 TMX3 DNM2

6.08e-0512971681833545068
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

ATR ACADS PIGS NAPG TTYH3 ECHDC3 MET PASK USO1 TRIM9 LTN1 TMED9 LRBA FUT8 MUL1 GARRE1

6.10e-0510611681633845483
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

GAPVD1 TBC1D15 ATR TCP1 SRP68 ANKHD1 LRPPRC KIDINS220 AP2A2 USO1 EIF2S1 CSNK1E EIF4A1 SUPT16H ABCD3 TMED9 ANAPC7 MGAM2 CDK4

6.40e-0514251681930948266
Pubmed

A protein interaction landscape of breast cancer.

TPP2 GAPVD1 GPS1 SRP68 EZH2 THOC5 LRPPRC AP2A2 BRD9 SUPT16H DNM2 CDK4

6.50e-056341681234591612
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

GAPVD1 TBC1D15 TCP1 GPS1 SRP68 LRPPRC USO1 EIF2S1 SUPT16H ABCD3 LRBA DNM2

6.90e-056381681233239621
Pubmed

Dynamin-2 reduction rescues the skeletal myopathy of a SPEG-deficient mouse model.

SPEG DNM2

6.94e-053168235763354
Pubmed

Reactive Neutrophil Responses Dependent on the Receptor Tyrosine Kinase c-MET Limit Cancer Immunotherapy.

MET CDK4

6.94e-053168229045907
Pubmed

Phosphorylation of serine 51 in initiation factor 2 alpha (eIF2 alpha) promotes complex formation between eIF2 alpha(P) and eIF2B and causes inhibition in the guanine nucleotide exchange activity of eIF2B.

EIF2S1 EIF2AK1

6.94e-053168211041858
Pubmed

Centrosomal anchoring of the protein kinase CK1delta mediated by attachment to the large, coiled-coil scaffolding protein CG-NAP/AKAP450.

CSNK1D CSNK1E

6.94e-053168212270714
Pubmed

FISH patterns of ROS1, MET, and ALK with a correlation of ALK immunohistochemistry in lung cancer: a case for introducing ALK immunohistochemistry 'Equivocal' interpretation category in the Ventana anti-ALK (D5F3) CDx assay - A tertiary cancer center experience.

MET ROS1

6.94e-053168233402590
Pubmed

Identification of two gene variants associated with risk of advanced fibrosis in patients with chronic hepatitis C.

CPT1A POLG2

6.94e-053168216697732
Pubmed

Analysis of the status of EGFR, ROS1 and MET genes in non-small cell lung adenocarcinoma.

MET ROS1

6.94e-053168228952227
Pubmed

Combined c-Met/Trk Inhibition Overcomes Resistance to CDK4/6 Inhibitors in Glioblastoma.

MET CDK4

6.94e-053168229844123
Pubmed

Gene expression levels of Casein kinase 1 (CK1) isoforms are correlated to adiponectin levels in adipose tissue of morbid obese patients and site-specific phosphorylation mediated by CK1 influences multimerization of adiponectin.

CSNK1D CSNK1E

6.94e-053168225724478
Pubmed

A comparative study of structural and conformational properties of casein kinase-1 isoforms: insights from molecular dynamics and principal component analysis.

CSNK1D CSNK1E

6.94e-053168225665722
Pubmed

Interaction between very-KIND Ras guanine exchange factor and microtubule-associated protein 2, and its role in dendrite growth--structure and function of the second kinase noncatalytic C-lobe domain.

FRMPD2 KNDC1

6.94e-053168221385318
Pubmed

Casein kinase 1-epsilon or 1-delta required for Wnt-mediated intestinal stem cell maintenance.

CSNK1D CSNK1E

6.94e-053168228963394
Pubmed

HERG K(+) currents in human prolactin-secreting adenoma cells.

KCNH7 KCNH6

6.94e-053168212634931
Pubmed

Human Rad17 C-terminal tail is phosphorylated by concerted action of CK1δ/ε and CK2 to promote interaction with the 9-1-1 complex.

CSNK1D CSNK1E

6.94e-053168231353086
Pubmed

Sequence analysis of the cDNA for the human casein kinase I delta (CSNK1D) gene and its chromosomal localization.

CSNK1D CSNK1E

6.94e-05316828786104
Pubmed

M1 receptors mediate cholinergic modulation of excitability in neocortical pyramidal neurons.

CHRM1 CHRM5

6.94e-053168219657040
Pubmed

The expression pattern of Von Hippel-Lindau tumor suppressor protein, MET proto-oncogene, and TFE3 transcription factor oncoprotein in renal cell carcinoma in Upper Egypt.

TFE3 MET

6.94e-053168221299348
Pubmed

Human sulfatase 1 exerts anti-tumor activity by inhibiting the AKT/ CDK4 signaling pathway in melanoma.

SULF1 CDK4

6.94e-053168227806323
Pubmed

Role of M1, M3, and M5 muscarinic acetylcholine receptors in cholinergic dilation of small arteries studied with gene-targeted mice.

CHRM1 CHRM5

6.94e-053168221335473
Pubmed

The CDK4/6-EZH2 pathway is a potential therapeutic target for psoriasis.

EZH2 CDK4

6.94e-053168232701505
Pubmed

Targeting of the circadian clock via CK1δ/ε to improve glucose homeostasis in obesity.

CSNK1D CSNK1E

6.94e-053168227439882
Pubmed

Wnt5a promotes hippocampal postsynaptic development and GluN2B-induced expression via the eIF2α HRI kinase.

GRIN2B EIF2AK1

6.94e-053168233795747
Pubmed

Developmentally regulated expression of the mouse homologues of the potassium channel encoding genes m-erg1, m-erg2 and m-erg3.

KCNH7 KCNH6

6.94e-053168214643686
Pubmed

CKIepsilon/delta-dependent phosphorylation is a temperature-insensitive, period-determining process in the mammalian circadian clock.

CSNK1D CSNK1E

6.94e-053168219805222
Pubmed

The HRI branch of the integrated stress response selectively triggers mitophagy.

EIF2S1 EIF2AK1

6.94e-053168238340717
Pubmed

A MET-PTPRK kinase-phosphatase rheostat controls ZNRF3 and Wnt signaling.

MET PTPRK

6.94e-053168234590584
Pubmed

Loss of M5 muscarinic acetylcholine receptors leads to cerebrovascular and neuronal abnormalities and cognitive deficits in mice.

CHRM1 CHRM5

6.94e-053168216956767
Pubmed

Casein kinase 1 proteomics reveal prohibitin 2 function in molecular clock.

CSNK1D CSNK1E

6.94e-053168222384121
Pubmed

Muscarinic cholinergic receptor (M2) plays a crucial role in the development of myopia in mice.

CHRM1 CHRM5

6.94e-053168223649821
Pubmed

Expression levels of ROS1/ALK/c-MET and therapeutic efficacy of cetuximab plus chemotherapy in advanced biliary tract cancer.

MET ROS1

6.94e-053168227136744
Pubmed

M(3) muscarinic acetylcholine receptor plays a critical role in parasympathetic control of salivation in mice.

CHRM1 CHRM5

6.94e-053168215146045
Pubmed

Expression of the heparan sulfate 6-O-endosulfatases, Sulf1 and Sulf2, in the avian and mammalian inner ear suggests a role for sulfation during inner ear development.

MYO7A SULF1

6.94e-053168225370455
Pubmed

Potassium Ion Channel Protein (KCNH) Levels in Patients with Fibromyalgia Syndrome.

KCNH7 KCNH6

6.94e-053168235818223
Pubmed

Muscarinic acetylcholine receptor subtypes as agonist-dependent oncogenes.

CHRM1 CHRM5

6.94e-05316821905013
Pubmed

Heme-regulated eIF2α kinase in erythropoiesis and hemoglobinopathies.

EIF2S1 EIF2AK1

6.94e-053168231554636
Pubmed

Cholinergically stimulated gastric acid secretion is mediated by M(3) and M(5) but not M(1) muscarinic acetylcholine receptors in mice.

CHRM1 CHRM5

6.94e-053168215691866
Pubmed

Mapping of five subtype genes for muscarinic acetylcholine receptor to mouse chromosomes.

CHRM1 CHRM5 MET

7.16e-0517168310549128
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

ATR HS6ST2 PIGS GPS1 KIAA0319L PIGG PRSS23 CPT1A LRP1B MET PTPRK EDEM2 LTN1 RIMOC1 TMED9 TMX3 FUT8

7.75e-0512011681735696571
Pubmed

Large-scale structural analysis of the classical human protein tyrosine phosphatome.

GRIN2B MET PTPRB PTPRK

7.97e-0547168419167335
Pubmed

Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.

CUL3 TCP1 GPS1 RPS15 SRP68 ANKHD1 PASK LRPPRC AP2A2 CSNK1D EIF2S1 EIF4A1 SUPT16H ABCD3 TMED9 METTL17 ANAPC7 CDK4

8.76e-0513351681829229926
Pubmed

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.

TBC1D15 GPS1 THOC5 LRPPRC AP2A2 USO1 LTN1 ABCD3 TMX3 ANAPC7 DNM2

9.51e-055601681135241646
Pubmed

SERBP1 Promotes Stress Granule Clearance by Regulating 26S Proteasome Activity and G3BP1 Ubiquitination and Protects Male Germ Cells from Thermostimuli Damage.

TPP2 GAPVD1 TBC1D15 TCP1 GPS1 SRP68 LRPPRC AP2A2 USO1 EIF4A1 LRBA TMX3 ANAPC7 CDK4

1.00e-048781681437223481
Pubmed

A conserved acetylation switch enables pharmacological control of tubby-like protein stability.

CUL3 FAM120B GPS1 GPC3 AP2A2 CSNK1E ANAPC7

1.12e-04223168733187986
Pubmed

C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.

CUL3 TBC1D15 TCAF1 TCP1 RPS15 CPT1A LRPPRC CSNK1D EIF2S1 CSNK1E EIF4A1 ABCD3 TMED9 TMX3 ANAPC7 DNM2 CDK4

1.34e-0412571681737317656
Pubmed

PEX14 is required for microtubule-based peroxisome motility in human cells.

TCP1 LRPPRC ABCD3 DNM2

1.38e-0454168421525035
Pubmed

Ubiquitin-assisted phase separation of dishevelled-2 promotes Wnt signalling.

TCAF1 TCP1 AP2A2 CSNK1D CSNK1E ABCD3

1.38e-04161168636398662
Pubmed

Involvement of casein kinase 1 epsilon/delta (Csnk1e/d) in the pathogenesis of familial Parkinson's disease caused by CHCHD2.

CSNK1D CSNK1E

1.38e-044168237578019
Pubmed

miR-1 suppresses the growth of esophageal squamous cell carcinoma in vivo and in vitro through the downregulation of MET, cyclin D1 and CDK4 expression.

MET CDK4

1.38e-044168227247259
InteractionGPR17 interactions

TBC1D15 ATR ARMC9 TTYH3 PIGG ELOVL2 SACS USO1 LTN1 RIMOC1 LRBA ANAPC7 MUL1

3.26e-0728315613int:GPR17
Cytoband12q13.2

OR2AP1 OR6C1 OR6C75 OR6C6

5.10e-0555168412q13.2
GeneFamilyOlfactory receptors, family 6

OR6N2 OR6N1 OR6C1 OR6C75 OR6C6

2.09e-05511195153
GeneFamilyDyneins, axonemal

DNAH7 DNAH1 DNAH6

1.77e-04171193536
GeneFamilyCholinergic receptors muscarinic

CHRM1 CHRM5

4.24e-0451192180
GeneFamilyWD repeat domain containing|BEACH domain containing

WDFY4 LRBA

1.50e-03911921230
GeneFamilyOlfactory receptors, family 1

OR1J4 OR1L1 OR1A1

2.30e-03401193147
GeneFamilyPotassium voltage-gated channels

KCNH7 KCNH6 KCNG1

2.30e-03401193274
GeneFamilyOxysterol binding proteins|Pleckstrin homology domain containing

OSBP OSBP2

2.72e-03121192670
GeneFamilyFucosyltransferases|Blood group antigens

FUT5 FUT8

3.20e-03131192434
GeneFamilyFibronectin type III domain containing

PTPRB PTPRK TRIM9 LRFN5 ROS1

4.14e-031601195555
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MGAM GRID1 GRIN2B CHRM1 LRP1B DNAH1 SLITRK2 ROS1

4.67e-0718416682cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MGAM GRID1 GRIN2B CHRM1 LRP1B DNAH1 SLITRK2 ROS1

4.67e-071841668ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MGAM GRID1 GRIN2B CHRM1 LRP1B DNAH1 SLITRK2 ROS1

4.67e-0718416682b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell3'-Adult-SmallIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PRSS23 CHRM5 FRY SLC8A3 PTPRB MYO3B GARRE1

3.99e-061731667b57d14e2c2368304cb903562d06ce8228f53857c
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FRMPD2 DNAH7 EFHC2 KNDC1 DNAI4 DNAH6 BAIAP3

6.20e-0618516675e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

KCNH7 HS6ST2 SIM2 LRP1B ABCA9 MET MYO3B

6.65e-06187166777886f99c229610abd28c4c370d2c7d1536c9782
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SPEG LRP1B SACS LRFN5 GADL1 ELAVL2 DCLK2

9.04e-0619616679830fb3da7a60f65ad463e9054bb77c06b025e4d
DrugJosamycin [16846-24-5]; Down 200; 4.8uM; PC3; HT_HG-U133A

ZMYND11 SPEG KIAA0319L ZNF783 PASK PTPRB SMPDL3B ZNF84 ZC3H7B BAIAP3

1.73e-06197164104631_DN
Diseasepancreatic cancer (biomarker_via_orthology)

EZH2 MET CDK4

5.29e-0671593DOID:1793 (biomarker_via_orthology)
Diseasemelanoma

CUL3 MYO7A PRSS23 LRP1B MET PTPRK ROS1 CDK4

6.33e-052481598C0025202
DiseaseSchizophrenia

GPS1 GRID1 GRIN2B DTNBP1 CHRM1 IL18R1 CHRM5 KCNH6 MET EIF2S1 CSNK1E EDEM2 ELAVL2 FUT8 PLXNA2

9.15e-0588315915C0036341
Diseaseglioblastoma (is_implicated_in)

EZH2 PTPRB CDK4

2.86e-04241593DOID:3068 (is_implicated_in)
Diseasesyndromic X-linked intellectual disability Najm type (implicated_via_orthology)

CSNK1D CSNK1E

5.95e-0471592DOID:0060807 (implicated_via_orthology)
Diseaseheart conduction disease (implicated_via_orthology)

KCNH7 KCNH6 MME

6.79e-04321593DOID:10273 (implicated_via_orthology)
Diseaselong QT syndrome (implicated_via_orthology)

KCNH7 KCNH6

1.26e-03101592DOID:2843 (implicated_via_orthology)
Diseasehepatocellular carcinoma (is_marker_for)

EZH2 IL18R1 LRP1B MET PTPRB GPC3 ANXA10

1.28e-033011597DOID:684 (is_marker_for)
Diseaseglycerophosphorylcholine measurement

GRIN2B DCLK2

1.54e-03111592EFO_0020018
Diseasepsychological resilience measurement

SLC7A7 DCLK2

1.84e-03121592EFO_0009945
Diseaseouter ear morphology trait

MYO3B LRBA

1.84e-03121592EFO_0007664
Diseaseepilepsy (implicated_via_orthology)

KCNH7 GRIN2B LRP1B KCNH6 SCN10A

1.94e-031631595DOID:1826 (implicated_via_orthology)
DiseaseOsteosarcoma

EZH2 MET EIF2S1

2.09e-03471593C0029463
Diseasesurvival time, breast carcinoma

KCNH7 ECHDC3

2.16e-03131592EFO_0000305, EFO_0000714
Diseaseobsolete_red blood cell distribution width

CUL3 TPP2 PGS1 ATR ACADS ITGAD EZH2 EIF4A1 BRD9 ELAVL2 OSBP2 EIF2AK1 ZC3H7B GARRE1 ADIPOR2 DNM2

2.59e-03134715916EFO_0005192
DiseaseAlzheimer's disease (is_marker_for)

ATR GRIN2B SLC8A3 CSNK1D EIF2S1 CSNK1E

2.77e-032571596DOID:10652 (is_marker_for)
DiseaseAutosomal Recessive Centronuclear Myopathy

SPEG DNM2

2.89e-03151592C3645536
DiseaseAutistic Disorder

ZMYND11 GRIN2B WDFY4 MET PASK ASMT

2.99e-032611596C0004352
DiseaseIntellectual Disability

ZMYND11 ARMC9 GRIN2B FRY ADPRS SACS SUPT16H FUT8

3.03e-034471598C3714756
Diseaselysosomal storage disease (implicated_via_orthology)

SLC66A1 TFE3

3.29e-03161592DOID:3211 (implicated_via_orthology)
DiseaseR-6-hydroxywarfarin measurement

NAPG LRP1B ENTPD3 LRBA

3.42e-031141594EFO_0803327
DiseaseBenign neoplasm of stomach

ATR MET

3.72e-03171592C0153943
Diseaseresponse to radiation, Urinary retention

LRP1B DNM2

3.72e-03171592GO_0009314, HP_0000016
DiseaseNeoplasm of uncertain or unknown behavior of stomach

ATR MET

3.72e-03171592C0496905
DiseaseCarcinoma in situ of stomach

ATR MET

3.72e-03171592C0154060
Diseaseidiopathic dilated cardiomyopathy

MGAM TCAF1 FAM120B

4.20e-03601593EFO_0009094
DiseaseChronic myeloproliferative disorder

ATR CENPE

4.65e-03191592C1292778
Diseasedocosahexaenoic acid measurement

TDRD15 TMC4 CPT1A ELOVL2

5.02e-031271594EFO_0007761
Diseasecholangiocarcinoma (is_marker_for)

UGT1A9 MET OSBP2

5.03e-03641593DOID:4947 (is_marker_for)
Diseasetemporal lobe epilepsy (is_marker_for)

GRIN2B DTNBP1

5.14e-03201592DOID:3328 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
MFTLLLSNYYSRLEG

LINC00596

1

Q86U02
AEAYQSMYGRDLIGD

ANXA10

56

Q9UJ72
AGLDYLAYAIAMEEI

ACADS

91

P16219
LDYSYLLGLLEDMQA

BAIAP3

471

O94812
LKSDEMELLYSAYGD

BRD9

401

Q9H8M2
MDYLGASESEIVYLA

ABCA9

1191

Q8IUA7
EYVMSIDSLQLGYAE

CPT1A

486

P50416
MGSSEDQAYRLLNDY

ASMT

1

P46597
ETNLDAYDPYLIAMS

CCNQ

61

Q8N1B3
SYYTDMEEIGNLLSN

PIK3AP1

261

Q6ZUJ8
AEMLSYLETADYSIR

AP2A2

406

O94973
DLNTSDIMQVSLYGY

ENTPD3

236

O75355
GLLLTSMAYDRYVAI

OR2L2

111

Q8NH16
LMASLYITGAALYAA

ADIPOR2

316

Q86V24
GVTEFYLLAAMSYDR

OR6C1

106

Q96RD1
LAAGTMYDLCVLAIY

LRFN5

476

Q96NI6
LLESEDSYLMGVYIG

LTN1

931

O94822
YQEAMDQYSIALSLD

ANAPC7

491

Q9UJX3
ESLLLASMAYDRYVA

OR8U8

111

P0C7N1
SLGATECYLLTAMAY

OR6N1

106

Q8NGY5
DSLYYGDLILQMLSE

PTPRB

1821

P23467
EALLLGFMSYDRYVA

OR2AK2

126

Q8NG84
YMDLAYNSSLQLPDL

PASK

391

Q96RG2
SYMSNEVRYELESGL

IL18R1

446

Q13478
DMLGYDLYSSALADI

KIDINS220

436

Q9ULH0
SDAIYSALYDGTNMI

LRP1B

1446

Q9NZR2
LVYSDNGSVMSLYNI

HSFX4

296

A0A1B0GTS1
SSLYDAMVAAQIPYD

MGAM2

1216

Q2M2H8
LSLEELVNGMYRIYD

GPC3

301

P51654
LSAMQEGDYTYQLTV

KIAA0319L

561

Q8IZA0
LDRYSEYGAAVLMLL

KCNH7

541

Q9NS40
SYSLFALVMLGNTLY

SLC66A1

216

Q6ZP29
SIAEMGAYVSLLEYN

EIF2S1

26

P05198
LYYTSNALTADMADP

SMPDL3B

196

Q92485
LSDYTLEYSVALLMN

ARMC9

471

Q7Z3E5
SSLYDEMVAAQIPYD

MGAM

2156

O43451
AMSELISSIADYYGI

METTL25

161

Q8N6Q8
LYGNCIMQEDESYLL

GAPVD1

136

Q14C86
DRYSEYGAAVLFLLM

KCNH6

391

Q9H252
DGSAMVYNLANALRY

DCLK2

491

Q8N568
IGDIDNAMRTFLNYY

EDEM2

326

Q9BV94
QDLGTAYYLTSQAMV

ECHDC3

261

Q96DC8
AYYLTSQAMVDNLAL

ECHDC3

266

Q96DC8
RMFVISYYLGDDTIS

EFHC2

451

Q5JST6
EASMFRVLIGTYYDN

EZH2

436

Q15910
DMNLSESLLRGIYAY

EIF4A1

36

P60842
VGEETMADYLLYTLN

MTG1

231

Q9BT17
YTLLLYGTAEDMTAR

PCSK4

571

Q6UW60
SYQYDGMDISNLAVD

PLXNA2

766

O75051
ATVENYLLASMAYDR

OR5B2

106

Q96R09
ATVENYLLASMAYDR

OR5B3

106

Q8NH48
TGYFNLTQAYMDLVL

PGS1

386

Q32NB8
YYTDLEAFAMVTAGL

PDE6B

581

P35913
SLDLEQYAASYSGLM

GPS1

41

Q13098
DMEQYLSTGYLQIAE

DTNBP1

206

Q96EV8
LESLGYVLMYFNLGS

CSNK1D

196

P48730
IAVTMIALYATYDDG

MME

41

P08473
GMQYYLSSQDFDSLL

MUL1

216

Q969V5
VQLMLYTYLSTEFIG

LRBA

586

P50851
VGYFLYNLIDSMSDS

LRPPRC

581

P42704
DLDRGMLAYLYDSFQ

POLG2

341

Q9UHN1
MLAYLYDSFQLTENS

POLG2

346

Q9UHN1
GYLETMQSSLEQLYS

POLG2

416

Q9UHN1
MTLLPGDNSDYDYSA

KCNG1

1

Q9UIX4
LRDMYLSGSLYDDLQ

MIEF1

181

Q9NQG6
GATEFYLLAAMSYDR

OR2AP1

106

Q8NGE2
MGALSTERLQYYTQE

PLA2G4F

431

Q68DD2
LAYLYSSADQSSLME

DNM2

696

P50570
LVYSDNGSVMSLYNI

HSFX3

296

A0A1B0GWH4
ENMYYFSELALTLNA

OSBP

691

P22059
ENMYYFSELALTLNE

OSBP2

796

Q969R2
DNFLLTSMAYDRYVA

OR1J4

111

Q8NGS1
DSYLLAAMAIDRYVA

OR1L1

161

Q8NH94
NVDMRDSYLGYSTEL

ITGAD

396

Q13349
SLGASECYLLTAMAY

OR6N2

106

Q8NGY6
SDLANVDPMYQYSLE

DNAH1

3461

Q9P2D7
LLMELTRAYLAYADN

ATR

1396

Q13535
SYLELINLYLSMLSE

DNAH6

2666

Q9C0G6
EYDAKSDMYSLGVVL

EIF2AK1

506

Q9BQI3
YNLGITLLSAYMLAE

ELOVL2

71

Q9NXB9
LADFGLARIYSYQMA

CDK4

156

P11802
NLEELTYFGLAYMKS

FRMPD2

376

Q68DX3
DYALIAIGRYSMTIE

FBXL17

606

Q9UF56
GLSFEELYRNAYTMV

CUL3

51

Q13618
YLAMSGENRENTLFY

DPP8

101

Q6V1X1
LDLFQATLDYGMYSR

DPP8

136

Q6V1X1
ATLDYGMYSREEELL

DPP8

141

Q6V1X1
SDLYSLGLVSSYMDN

GARRE1

786

O15063
SLADLANIEPMYQYS

DNAH7

3216

Q8WXX0
DLIIGTFSMNLYTTY

CHRM1

71

P11229
EALYYTDDTAMARAL

ADPRS

71

Q9NX46
LLYADLDVFSSTYMQ

BRF2

141

Q9HAW0
NYDEAAMAIASLNGY

ELAVL2

326

Q12926
DLYDSYNAMELVSLS

DNAI4

321

Q5VTH9
NYLLEQYELSMSSAE

ERAP2

806

Q6P179
VMFYDSEYDIRGLQS

GRID1

166

Q9ULK0
RIEGLNFLDMELYSY

HS6ST2

476

Q96MM7
LGLMAYLYSSDAFLE

KNDC1

1256

Q76NI1
DYYSLVARFMTEALN

GADL1

126

Q6ZQY3
YADITLNMVTYLAEL

FRY

2216

Q5TBA9
DTSYLIAMLGCNDIY

SACS

4116

Q9NZJ4
QELSYTEGLSLVYMA

METTL17

146

Q9H7H0
YMEIYNETITDLLCG

CENPE

131

Q02224
QAESYLVYNIMSSGE

FAM120B

586

Q96EK7
GVTEFYLLAAMSYDR

OR6C75

106

A6NL08
LVYDYGCTSIVMLNE

PTPRK

1261

Q15262
ATVENYLLSSMAYDR

OR5B17

106

Q8NGF7
SVSVLLNYMYNAALE

KBTBD12

81

Q3ZCT8
ALGNTDSYILAAMAY

OR1A1

106

Q9P1Q5
DSYILAAMAYDRAVA

OR1A1

111

Q9P1Q5
YYFLAMLDSIDLGLS

OR52E8

66

Q6IFG1
GNFSVDSQILYYAML

PIGS

266

Q96S52
ESLLLASMAYDRYVA

OR8U1

111

Q8NH10
ALDGYFNLTMSYRSD

FUT5

161

Q11128
RSIMTDLYYLSQTDG

FUT8

161

Q9BYC5
INMALVVDTYYDDQL

MET

116

P08581
GISIYFNDNSLESYM

USO1

546

O60763
NGYALAQVMDTDIYV

SLC26A9

501

Q7LBE3
DVISLMLQAGYAEYF

TDRD15

651

B5MCY1
SLGVYCIDAYNETMT

TCAF1

121

Q9Y4C2
LYTQAILDMTYFEEN

RIMOC1

66

A6NDU8
DSSLVQYALLAEMGY

SEL1L2

496

Q5TEA6
QYALLAEMGYEVAQS

SEL1L2

501

Q5TEA6
GNANDIGMDYDYALL

PRSS23

236

O95084
SMFDGLQSLQYLYLE

SLITRK2

441

Q9H156
LDMSLYDSCYQIVGL

SIM2

196

Q14190
INLLTAEESANEYYM

SHOC1

296

Q5VXU9
LAYAAYLTAEMASLS

SLC9A5

286

Q14940
EAALSIYLENYATSM

TCP1

416

P17987
IYLENYATSMGSREQ

TCP1

421

P17987
YFSSSLYQALADMLE

HRC

681

P23327
ELSMEELLQQYAGAY

SRCAP

441

Q6ZRS2
NISMSVEGDYTYLRI

SUPT16H

556

Q9Y5B9
GVTEFYLLAAMSYDR

OR6C6

106

A6NF89
AQAYTAYLSGMLRFE

SRP68

186

Q9UHB9
SELLEDYYQSGRMLL

ABCD3

351

P28288
DLIIGIFSMNLYTTY

CHRM5

76

P08912
CSAGYYELAQVLLAM

ANKHD1

246

Q8IWZ3
DETMVIGNYRTQLYD

TMED9

56

Q9BVK6
YLAMDGFLLYELGDT

TMX3

231

Q96JJ7
TYRGVDLDQLLDMSY

RPS15

16

P62841
TYTYDLMANLAFIRG

TTC19

136

Q6DKK2
ASSEGYVLFYQLMQE

USP21

546

Q9UK80
IQYLLSGFELELYSM

NAA35

501

Q5VZE5
LESSYNDEMLSYLPG

TFE3

271

P19532
DVATYMVQLLQGLDY

SPEG

3061

Q15772
YMDNDYAKLGLSLVV

NAPG

261

Q99747
MILLSSGSLAFEDYY

SCN10A

1161

Q9Y5Y9
LMAYTVALANSYGRL

TMC4

666

Q7Z404
YESLISMDYAINQPD

ZNF398

176

Q8TD17
VMSDLYQETYIDDLG

ZDHHC4

221

Q9NPG8
YYTVLDMRDILASDA

SLC7A7

281

Q9UM01
FGTAEMLNYSVNIYD

TPP2

236

P29144
MLNYSVNIYDDGNLL

TPP2

241

P29144
DISNFEYLMYLNTAA

WDFY4

2546

Q6ZS81
SEISQNALMYYSGRL

ROS1

881

P08922
YDFDLGYVQGMSDLL

TBC1D15

446

Q8TC07
QVRSIYSLLMGSYND

UGT1A9

101

O60656
VMLENYSSLVSLGYE

ZNF84

36

P51523
GVSDYDYLDLDKMSL

TRIM9

56

Q9C026
AQRALYGEVMLENYA

ZNF621

31

Q6ZSS3
YGEVMLENYANVASL

ZNF621

36

Q6ZSS3
YGADSEQADIARMLY

ZMYND11

231

Q15326
LSSDEMYLLDSGGQY

XPNPEP2

441

O43895
DAGLAGDTNLYYMAL

THOC5

541

Q13769
LSLSAQVAQYDIYSM

PIGG

421

Q5H8A4
MVEEYSVLSGDILQY

TTYH3

281

Q9C0H2
LYNMLVETGELENTY

SULF1

296

Q8IWU6
EAMAFASYYSLDNLV

TKTL1

136

P51854
DYLSAISELNYMTQI

PPIP5K1

871

Q6PFW1
VMRGNYETLVSLDYA

ZNF783

171

Q6ZMS7
DLYVDVMLENYSNLV

ZNF283

96

Q8N7M2
LVQYMEGLNVADYAA

ZC3H7B

56

Q9UGR2
LESLGYVLMYFNLGS

CSNK1E

196

P49674
DLDQLVEMANYYALS

SLC8A3

331

P57103
QRLDEAMISYILYGA

MYO3B

126

Q8WXR4
LASQQYFVDYGSEMI

MYO7A

1391

Q13402
LDAFIYDAAVLNYMA

GRIN2B

726

Q13224